Hub : Genes

Vti1a

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose alternative polyA XM_039090089.1 0.03 0.02 1.8e-03 0.03 0.01 0.02 0.02 5.4e-04 2.1e-02 2.1e-03 1.2e-03
2 Adipose alternative polyA XM_039090089.1 0.02 0.02 4.8e-03 0.02 0.01 0.01 0.02 1.8e-03 5.0e-02 7.4e-03 4.4e-03
3 LHb intron excision ratio chr1_254426339_254430839 0.14 0.11 6.9e-03 0.1 0.04 0.12 0.07 2.2e-03 5.2e-02 7.2e-04 1.1e-02
4 Liver mRNA stability Vti1a 0.03 0.02 3.4e-04 0.02 0.02 0.02 0.02 1.7e-03 1.3e-03 1.3e-03 2.0e-03
5 BLA gene expression Vti1a 0.08 0.06 1.3e-03 0.03 0.04 0.03 0.02 9.2e-03 3.4e-03 1.1e-02 2.0e-02
6 NAcc gene expression Vti1a 0.04 0.04 4.7e-04 0.04 0.03 0.03 0.03 6.1e-05 2.9e-04 4.5e-04 1.2e-04
7 BLA mRNA stability Vti1a 0.1 0.07 8.6e-05 0.06 0.06 0.03 0.06 2.5e-04 3.3e-04 1.6e-02 2.5e-04
8 PL gene expression Vti1a 0.09 0.05 8.3e-09 0.06 0.07 0.06 0.07 2.5e-07 1.6e-08 1.1e-07 7.5e-08
9 NAcc mRNA stability Vti1a 0.03 0.03 3.8e-03 0.02 0.01 0.01 -0 1.4e-03 1.3e-02 9.4e-03 4.1e-01
10 OFC mRNA stability Vti1a 0.22 0.16 4.2e-03 0.12 0.04 0.09 0.08 7.3e-04 4.5e-02 4.6e-03 5.3e-03
11 Liver intron excision ratio chr1_254535612_254536577 0.03 0.02 4.4e-03 0.02 0.01 0.02 0 3.9e-03 4.6e-02 2.2e-03 8.3e-02
12 PL mRNA stability Vti1a 0.09 0.06 3.0e-07 0.04 0.06 0.06 0.06 1.6e-05 1.4e-07 1.2e-07 2.0e-07
13 Brain gene expression Vti1a 0.07 0.05 3.8e-05 0.04 0.06 0.05 0.05 2.7e-04 6.2e-06 3.2e-05 3.9e-05
14 Brain mRNA stability Vti1a 0.15 0.08 4.1e-12 0.13 0.14 0.14 0.14 2.1e-12 1.1e-12 1.0e-12 1.3e-12
15 IL gene expression Vti1a 0.23 0.16 4.1e-03 0.08 0.09 0.09 0.08 5.2e-03 4.2e-03 3.7e-03 5.7e-03

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15
Bone: apparent density0.71.24.92.22.22.0-1.10.5-0.6-0.40.2-0.3-0.20.20.5-0.60.8-0.6
Area under the delay curve0.50.51.11.11.11.1-0.3-0.20.40.7-0.40.40.20.70.9-0.91.10.4
BMI with tail4.213.525.34.54.53.8-5.04.7-4.7-4.14.0-3.4-2.9-3.1-2.52.2-1.7-1.6
BMI without tail1.02.24.91.91.91.6-2.22.0-2.2-1.51.6-0.8-0.4-1.0-0.60.5-0.2-1.2
Body weight5.623.344.16.26.24.5-6.66.0-5.8-5.05.2-4.6-4.2-4.2-3.33.0-2.2-2.5
Weight adjusted by age2.83.26.61.21.20.4-2.12.6-2.1-2.52.4-2.0-1.4-2.0-1.61.7-1.3-0.4
Bone surface0.40.72.11.31.31.4-0.80.6-0.9-0.50.4-0.5-0.6-0.2-0.10.1-0.1-1.5
Bone volume1.32.36.92.62.62.2-1.91.5-1.5-1.41.0-1.2-1.3-0.6-0.30.20.0-1.1
Breakpoint value in progressive ratio session0.91.02.10.50.50.80.5-0.70.81.1-1.00.80.81.31.4-1.41.40.8
Number of licking bursts0.60.72.81.11.11.7-0.0-0.30.10.8-0.60.50.30.90.9-1.01.10.2
Context. condit. distance diff. score0.60.72.7-1.0-1.0-1.70.10.3-0.3-0.30.50.20.2-0.7-0.90.9-0.8-1.4
Locomotion velocity, session 12.22.33.8-0.9-0.90.81.8-1.91.51.8-1.91.31.51.71.4-1.51.31.9
Locomotion distance, session 10.10.10.3-0.4-0.40.20.3-0.1-0.2-0.20.00.10.1-0.3-0.50.4-0.4-0.5
Locomotion velocity, session 20.60.72.2-0.6-0.6-0.00.00.3-0.8-0.40.7-0.5-0.5-1.0-1.41.3-1.5-1.0
Locomotion distance, session 20.91.32.31.51.50.9-1.51.3-1.3-1.41.2-1.0-1.0-1.0-0.80.7-0.5-0.7
Locomotion velocity, session 30.20.21.2-0.0-0.0-0.2-0.20.4-0.5-0.30.50.1-0.1-0.6-0.70.7-0.4-1.1
Locomotion distance, session 31.31.42.8-0.3-0.3-1.6-0.91.1-1.3-1.41.3-0.6-0.3-1.5-1.71.6-1.1-1.4
Stereotopy head waving bouts, day 30.10.11.10.40.40.1-0.20.10.2-0.20.0-0.20.00.00.1-0.10.41.0
Stereotopy head waving duration, day 31.01.21.8-0.6-0.60.41.3-1.31.21.3-1.31.11.21.31.2-1.11.00.9
Locomotion velocity, session 70.10.10.40.30.30.3-0.10.0-0.3-0.1-0.00.20.40.1-0.0-0.10.1-0.6
Locomotion distance, session 70.20.31.70.10.1-0.4-0.30.3-0.5-0.60.4-0.1-0.1-0.5-0.70.6-0.6-1.3
Stereotopy head waving bouts, day 70.10.10.60.10.10.80.2-0.2-0.10.5-0.20.20.40.30.3-0.30.30.1
Stereotopy head waving duration, day 70.20.32.40.60.61.5-0.10.0-0.30.4-0.10.10.10.30.4-0.40.3-0.3
Locomotion velocity, session 80.20.20.8-0.7-0.70.20.9-0.70.40.5-0.50.60.10.2-0.10.1-0.1-0.2
Locomotion distance, session 80.40.62.4-0.4-0.4-0.8-0.20.5-0.7-0.80.7-0.0-0.1-0.9-1.11.0-0.9-1.5
Degree of sensitization distance1.41.42.6-0.1-0.11.21.2-1.51.21.5-1.51.00.71.61.5-1.51.00.6
Degree of sensitization stereotypy0.10.10.60.20.20.80.1-0.2-0.00.6-0.30.20.40.40.4-0.50.40.1
Conditioned locomotion0.10.10.20.30.3-0.5-0.10.10.1-0.40.2-0.3-0.4-0.2-0.20.3-0.10.0
Cocaine response after cond. corrected1.01.15.4-1.8-1.8-2.30.8-0.40.40.5-0.10.80.9-0.2-0.40.4-0.5-1.1
Cocaine response after cond. not corrected1.21.34.3-2.0-2.0-2.11.3-0.90.90.8-0.61.01.10.3-0.00.0-0.2-0.3
Cocaine response before conditioning0.80.93.0-0.1-0.10.70.9-1.21.10.9-1.20.60.41.11.0-1.10.91.7
Saline control response0.10.10.3-0.6-0.6-0.40.4-0.20.20.2-0.00.10.1-0.2-0.30.3-0.30.3
Bone: connectivity density0.10.21.20.20.20.50.3-0.40.10.4-0.40.60.60.30.3-0.30.2-1.1
Bone: cortical apparent density1.72.35.9-1.7-1.7-1.6-0.00.8-1.0-1.01.3-0.8-0.7-1.8-2.22.2-2.4-1.5
Bone: cortical area2.84.212.53.03.03.5-2.52.0-2.7-1.71.5-1.2-1.2-0.7-0.50.3-0.3-2.2
Bone: cortical porosity0.60.61.40.70.70.80.2-0.60.70.9-0.80.90.80.91.0-1.01.2-0.1
Bone: cortical porosity0.70.71.71.01.01.30.0-0.40.50.8-0.70.80.70.91.1-1.11.30.1
Bone: cortical thickness1.93.15.62.22.22.4-2.22.0-2.4-1.81.7-1.3-1.1-1.2-1.00.9-0.7-1.9
Bone: cortical thickness2.02.34.41.61.61.9-1.61.6-2.1-1.61.5-1.7-1.4-1.3-1.31.2-1.2-0.6
Bone: cortical tissue density1.72.25.6-1.8-1.8-1.70.10.7-0.9-0.91.2-0.7-0.7-1.7-2.12.1-2.4-1.4
Condit. Reinf. active minus inactive responses0.91.03.3-1.4-1.4-1.00.9-0.80.40.8-0.71.21.80.70.5-0.70.80.8
Condit. Reinf. active-inactive response ratio1.11.23.8-1.6-1.6-0.91.2-1.00.61.0-0.91.21.90.80.6-0.70.60.6
Condit. Reinf. active responses0.50.62.3-0.6-0.6-0.30.3-0.40.10.4-0.50.91.50.60.6-0.81.11.3
Condit. Reinf. inactive responses0.30.41.30.60.60.7-0.3-0.1-0.00.1-0.30.50.50.50.6-0.81.11.0
Incentive salience index mean1.51.94.4-1.9-1.9-1.31.4-1.20.81.1-1.11.52.11.00.7-1.00.91.4
Condit. Reinf. lever presses1.01.42.5-1.3-1.3-0.41.4-1.30.91.1-1.21.21.41.10.9-1.10.91.6
Condit. Reinf. active minus inactive responses4.25.210.7-1.3-1.3-0.12.0-2.21.32.7-2.53.23.32.92.6-2.82.60.0
Condit. Reinf. active-inactive response ratio3.94.18.4-1.9-1.9-0.72.0-2.11.12.4-2.22.82.92.41.9-2.21.8-0.1
Condit. Reinf. active responses2.63.67.0-0.3-0.30.91.3-1.70.92.1-2.12.62.52.52.4-2.62.5-0.0
Condit. Reinf. inactive responses0.40.51.60.90.91.3-0.1-0.20.30.5-0.50.50.30.71.0-0.91.1-0.0
Condit. Reinf. lever presses1.72.34.3-0.2-0.21.81.1-1.50.71.9-1.71.71.72.01.9-2.11.70.6
Condit. Reinf. lever reinforcers received2.73.87.0-0.5-0.50.81.4-1.81.12.2-2.12.72.62.62.5-2.62.50.1
Conditioned reinforcement - actives0.20.20.5-0.7-0.7-0.60.5-0.50.30.4-0.40.60.50.30.3-0.30.2-0.1
Conditioned reinforcement - inactives0.20.31.00.80.81.0-0.40.00.00.2-0.20.10.10.40.5-0.60.70.4
Conditioned locomotion0.20.21.20.50.51.10.1-0.40.30.3-0.4-0.5-1.10.20.2-0.1-0.10.2
Patch foraging indifference point 0 sec1.01.63.61.91.91.6-1.81.6-1.4-1.21.3-1.0-0.8-0.9-0.50.4-0.0-0.2
Patch foraging indifference point AUC1.51.84.61.71.71.3-0.2-0.61.20.7-1.00.30.21.21.8-1.61.92.1
Delay disc. indifference point, 0s delay0.70.82.81.71.71.6-1.00.7-0.6-0.40.6-0.6-0.9-0.3-0.10.20.0-0.4
Delay disc. indifference point, 16s delay0.90.91.70.40.40.80.5-0.91.11.3-1.00.80.71.11.3-1.31.30.4
Delay disc. indifference point, 2s delay0.20.20.70.80.80.5-0.50.3-0.2-0.20.3-0.4-0.8-0.3-0.10.2-0.1-0.3
Delay disc. indifference point, 24s delay1.71.63.11.41.41.70.2-0.81.01.4-1.10.70.51.41.7-1.71.81.1
Delay disc. indifference point, 4s delay0.40.40.9-0.2-0.2-0.20.3-0.50.60.7-0.61.00.70.70.8-0.80.9-0.0
Delay disc. indifference point, 8s delay0.90.93.31.81.81.6-0.90.30.00.3-0.0-0.1-0.10.50.9-0.81.10.6
Indifference point function ln k0.50.72.8-0.8-0.8-0.70.10.4-0.7-0.40.6-0.1-0.1-0.7-1.11.0-1.1-1.7
Indifference point function log k0.50.72.8-0.8-0.8-0.70.10.4-0.7-0.40.6-0.1-0.1-0.7-1.11.0-1.1-1.7
Patch foraging total patch changes 0 sec0.91.54.32.12.11.9-1.81.4-1.2-1.01.1-0.9-0.7-0.7-0.20.10.30.1
Patch foraging total patch changes 12 sec0.70.92.51.61.61.5-0.60.00.20.3-0.30.30.30.61.0-1.01.40.8
Patch foraging total patch changes 18 sec1.72.27.02.62.62.5-1.00.10.40.3-0.40.1-0.00.81.5-1.42.01.5
Patch foraging total patch changes 24 sec2.32.87.01.71.72.3-0.2-0.71.01.1-1.20.90.61.62.1-2.22.62.5
Patch foraging total patch changes 6 sec1.31.96.52.62.62.5-1.81.3-1.0-0.70.8-0.8-0.6-0.30.3-0.30.70.0
Patch foraging time to switch 0 sec0.50.72.7-1.6-1.6-0.80.9-0.60.20.8-0.30.80.70.0-0.30.2-0.5-1.3
Patch foraging water rate 0 sec0.50.82.71.61.61.0-1.10.9-0.6-1.10.7-0.9-0.5-0.5-0.30.30.10.8
Patch foraging water rate 12 sec0.30.41.61.31.30.5-0.90.6-0.2-0.60.4-0.5-0.3-0.10.2-0.10.50.5
Patch foraging water rate 18 sec0.60.92.40.80.8-0.0-1.11.2-1.1-1.61.1-1.0-0.6-0.9-1.00.8-0.60.0
Patch foraging water rate 24 sec1.11.64.12.02.01.2-1.81.4-1.4-1.31.2-1.0-0.9-0.8-0.70.6-0.2-0.6
Patch foraging water rate 6 sec1.11.62.41.41.41.3-1.31.2-1.3-1.31.2-1.5-1.6-1.2-1.31.3-0.9-0.2
Seeking ratio, delayed vs. immediate footshock0.10.20.70.70.70.80.0-0.10.10.2-0.1-0.1-0.40.10.2-0.00.1-0.8
Distance traveled before self-admin2.12.24.9-1.1-1.1-1.5-0.71.2-1.2-1.61.5-1.3-1.0-1.8-2.22.0-2.2-0.6
Distance traveled after self-admin3.43.86.40.70.70.2-1.72.1-2.0-2.02.3-2.4-2.1-2.4-2.52.4-2.5-0.9
Extensor digitorum longus weight0.20.93.21.81.80.6-1.41.0-0.4-1.20.7-0.8-0.9-0.5-0.00.00.50.6
Bone: elastic displacement0.10.20.9-0.1-0.1-0.00.1-0.30.20.4-0.30.60.90.40.4-0.50.5-0.1
Bone: elastic work1.51.93.50.90.90.9-1.61.6-1.9-1.61.6-1.3-1.1-1.5-1.51.4-1.4-1.1
Bone: endosteal estimation0.61.33.92.02.01.7-1.61.2-1.4-0.90.8-0.8-1.0-0.3-0.1-0.00.1-0.8
Bone: endosteal perimeter1.43.08.32.32.32.9-2.01.7-2.6-1.31.3-1.4-1.3-0.7-0.70.5-0.7-2.1
Epididymis fat weight5.312.327.15.25.24.3-5.04.2-4.0-3.83.3-3.2-2.8-2.3-1.41.1-0.5-0.2
Delta time in closed arm before/after self-admin0.80.81.7-0.9-0.9-1.3-0.40.7-0.6-1.00.8-0.9-0.6-0.9-1.01.0-1.00.9
Delta time in open arm before/after self-admin1.11.02.91.41.41.70.1-0.50.61.0-0.80.40.21.11.3-1.31.20.6
Diff in mean of infusions in LGA sessions2.62.85.5-2.3-2.3-1.92.0-1.71.41.6-1.52.12.21.41.1-1.10.9-0.5
Delay discount exponential model param0.60.61.3-1.1-1.1-1.10.30.2-0.4-0.70.4-0.4-0.2-0.7-1.01.0-1.1-0.5
Extinction: sum of active levers before priming1.01.01.90.80.80.90.5-1.01.21.1-1.20.70.41.21.2-1.41.40.6
Active lever presses in extinction session 60.40.41.81.21.21.3-0.50.2-0.10.0-0.0-0.5-0.60.20.4-0.30.30.8
Bone: final force1.11.85.91.81.82.4-1.51.3-1.9-1.31.0-1.2-1.1-0.6-0.70.4-0.5-0.7
Bone: final moment1.42.26.12.12.12.5-1.81.5-2.1-1.61.2-1.4-1.2-0.7-0.70.5-0.5-0.7
Food consumed during 24 hour testing period0.30.43.6-0.0-0.0-0.6-0.20.3-0.50.10.40.30.4-0.5-0.60.6-0.2-1.9
Glucose3.55.37.62.52.52.1-2.82.6-2.7-2.52.4-2.6-2.3-2.2-2.01.9-1.6-0.8
Heart weight0.81.14.00.30.30.0-1.21.5-2.0-1.41.3-0.20.4-1.0-1.10.8-0.8-1.3
Delay discount hyperbolic model param0.30.30.9-0.9-0.9-0.80.30.1-0.3-0.50.3-0.3-0.1-0.5-0.80.7-0.9-0.3
Intermittent access intake day 1-15 change0.50.51.91.41.41.2-1.00.7-0.4-0.30.4-0.30.10.20.1-0.30.70.5
Intermittent access intake escalation1.11.02.41.51.51.1-1.61.4-1.1-1.01.1-1.0-0.5-0.6-0.70.5-0.00.1
Intermittent access intake escalation 20.90.92.31.51.51.4-1.31.1-0.9-0.70.9-0.9-0.6-0.5-0.60.4-0.1-0.1
Intermitt. access day 1 inactive lever presses0.80.84.01.61.62.0-0.70.3-0.00.3-0.10.0-0.10.60.6-0.71.1-0.1
Intermitt. access day 15 inactive lever presses0.30.30.6-0.7-0.70.00.3-0.40.50.4-0.50.70.80.70.5-0.70.70.5
Intermitt. access escalation Index0.60.51.00.80.81.0-0.70.6-0.6-0.40.6-0.9-1.0-0.7-0.70.6-0.6-0.3
Intermittent access day 1 total infusions0.91.02.10.80.80.90.4-0.80.91.0-1.10.90.71.21.3-1.31.50.7
Intermittent access day 15 total infusions0.60.61.81.31.31.2-0.50.10.10.3-0.20.30.60.70.7-0.81.30.5
Intermittent access terminal intake (last 3 days)0.50.61.41.21.21.2-0.2-0.20.30.5-0.40.40.50.70.7-0.91.10.5
Intermittent access total infusions0.70.82.11.41.41.4-0.2-0.30.40.6-0.60.40.40.91.0-1.11.30.6
Intermittent access day 1 locomotion0.10.10.20.10.10.2-0.10.2-0.3-0.30.2-0.3-0.4-0.3-0.30.3-0.4-0.3
Intermittent access day 15 total locomotion0.60.62.51.61.61.4-0.90.7-0.4-0.50.4-0.6-0.3-0.10.0-0.10.40.5
Intermittent access total locomotion0.40.40.80.80.80.8-0.50.5-0.5-0.70.5-0.8-0.9-0.6-0.60.6-0.5-0.3
Intermittent access standard deviation1.81.95.22.22.22.3-0.3-0.40.80.8-0.90.30.21.31.5-1.61.91.2
Left kidney weight5.315.023.52.82.81.8-4.34.6-4.8-4.44.5-4.0-3.6-4.2-4.24.0-3.8-3.1
Right kidney weight4.713.122.93.03.02.2-4.24.4-4.8-3.94.2-3.3-3.0-3.8-3.73.4-3.0-3.5
Cocaine induced anxiety0.91.03.1-1.6-1.6-1.20.7-0.2-0.1-0.00.3-0.6-0.9-0.8-1.01.3-1.8-0.9
Post-drug Anxiety0.30.30.9-0.5-0.5-0.2-0.20.2-0.4-0.10.4-0.5-0.9-0.6-0.70.8-1.0-0.8
Baseline Anxiety2.02.28.32.92.92.8-1.70.9-0.6-0.30.3-0.5-0.50.30.6-0.81.30.8
Tail length0.10.20.60.40.4-0.0-0.30.1-0.20.3-0.10.60.70.40.5-0.50.7-0.8
Length with tail1.45.09.63.03.02.0-3.12.7-2.6-2.22.3-2.1-2.2-1.8-1.51.4-1.0-1.6
Length without tail4.59.716.23.73.72.7-4.03.7-3.4-3.33.3-3.3-3.4-2.8-2.42.3-1.8-1.6
Times rat made contact with spout1.01.23.51.91.91.0-1.41.2-0.9-1.01.0-0.9-0.8-0.9-0.60.6-0.1-0.6
Lifetime Intake0.80.92.21.31.31.3-0.2-0.40.60.7-0.70.50.41.01.1-1.21.50.7
Liver weight, left1.72.710.92.92.93.3-1.81.0-1.0-1.10.5-1.1-1.50.00.4-0.60.81.3
Liver weight, right5.49.019.74.44.44.2-3.83.2-3.0-3.12.6-3.0-3.2-2.0-1.51.3-0.9-0.4
Locomotor activity1.11.83.10.60.60.3-1.31.6-1.8-1.41.7-1.4-1.0-1.6-1.51.6-1.5-1.2
Locomotor testing distance2.44.06.10.60.60.3-1.82.3-2.5-2.12.4-2.1-1.8-2.4-2.42.4-2.5-1.9
Locomotor testing rearing1.01.52.70.40.40.5-1.21.5-1.6-1.21.5-1.3-1.1-1.4-1.41.3-1.6-1.2
Locomotion in novel chamber1.31.62.9-0.2-0.2-0.6-1.01.3-1.2-1.31.5-1.0-1.0-1.6-1.71.7-1.5-1.7
Locomotion in novel chamber post-restriction0.40.41.4-1.1-1.1-1.20.5-0.40.40.6-0.10.60.5-0.1-0.30.3-0.2-1.0
Fecal boli incidents, locomotor time 10.20.20.30.20.20.20.3-0.40.40.4-0.50.20.00.50.6-0.60.50.6
Change in fecal boli incidents, locomotor task0.30.31.2-1.1-1.1-0.90.5-0.20.20.2-0.20.50.80.20.2-0.10.10.2
Time >=10cm from walls, locomotor time 10.20.20.9-0.6-0.6-1.00.5-0.60.70.4-0.50.2-0.20.10.1-0.10.10.2
Bouts of movement, locomotor time 11.11.22.61.51.51.6-0.2-0.30.50.6-0.70.40.61.01.3-1.41.61.5
Total resting periods, locomotor time 11.01.12.61.51.51.6-0.3-0.20.30.4-0.50.30.60.91.1-1.21.41.6
Rest time, locomotor task time 10.20.20.40.70.70.4-0.40.6-0.5-0.40.5-0.5-0.1-0.4-0.30.3-0.30.1
Distance moved, locomotor task time 10.10.10.40.00.0-0.4-0.30.20.0-0.30.2-0.3-0.6-0.2-0.30.2-0.1-0.2
Vertical activity count, locomotor time 11.41.55.6-1.7-1.7-2.10.20.5-0.5-0.50.80.10.3-0.9-1.21.3-1.3-2.4
Time >=10cm from walls, locomotor time 20.20.20.70.70.70.4-0.50.3-0.0-0.40.2-0.6-0.80.10.3-0.20.30.8
Bouts of movement, locomotor time 20.50.51.0-0.8-0.8-0.61.0-1.00.70.9-0.80.90.90.70.5-0.50.4-0.1
Total resting periods, locomotor time 20.30.30.6-0.4-0.4-0.20.8-0.80.50.8-0.70.70.70.60.5-0.50.4-0.1
Rest time, locomotor task time 20.40.52.20.40.40.7-0.20.4-0.6-0.00.5-0.5-0.7-0.7-0.80.7-0.9-1.5
Distance moved, locomotor task time 20.50.61.7-0.1-0.1-0.50.2-0.40.90.3-0.70.60.70.91.1-1.11.31.3
Vertical activity count, locomotor time 20.10.10.20.20.2-0.4-0.20.30.0-0.40.2-0.10.30.10.3-0.00.2-0.3
Light reinforcement 10.61.02.2-1.3-1.3-0.61.5-1.31.01.0-1.11.21.01.00.7-0.80.60.0
Light reinforcement 20.50.61.6-1.0-1.0-0.41.3-1.10.71.0-0.90.90.50.70.3-0.30.1-0.6
Bone: marrow area0.71.44.12.02.01.7-1.61.2-1.4-0.90.8-0.8-1.0-0.3-0.1-0.00.1-0.8
Bone: maximum diameter2.54.616.03.63.64.0-2.61.9-2.4-1.51.2-1.3-1.7-0.3-0.1-0.10.1-1.9
Bone: maximum force1.01.75.81.51.52.4-1.41.2-2.1-1.21.0-0.9-0.8-0.6-0.80.5-0.7-1.3
Bone: maximum moment1.12.05.91.81.82.4-1.61.4-2.2-1.41.1-1.0-0.9-0.7-0.80.5-0.6-1.1
Mean time between licks in bursts0.50.82.2-0.4-0.4-0.30.6-0.70.60.9-0.81.31.51.00.9-1.11.20.2
Mean num. licks in bursts1.62.03.70.30.3-0.9-1.31.6-1.2-1.91.7-1.4-1.2-1.9-1.71.8-1.5-0.9
Cd content in liver2.83.05.1-2.2-2.2-2.22.1-1.81.81.8-1.72.01.91.51.3-1.30.9-0.1
Co content in liver0.60.61.1-0.0-0.0-0.8-0.50.6-0.3-1.00.8-1.0-1.0-1.0-1.01.0-0.90.8
Cu content in liver0.50.61.20.60.60.7-0.80.8-0.8-1.00.8-1.1-0.9-0.8-0.80.7-0.70.6
Fe content in liver0.10.10.60.30.3-0.8-0.40.20.30.10.20.10.0-0.10.1-0.00.3-0.1
K content in liver0.30.31.40.70.70.30.2-0.40.80.0-0.4-0.2-0.20.30.5-0.40.51.2
Mg content in liver0.70.71.40.90.91.00.3-0.70.80.4-0.80.30.30.91.1-1.11.20.9
Mn content in liver0.20.21.9-0.6-0.6-1.40.4-0.20.2-0.0-0.00.30.3-0.1-0.20.2-0.2-0.6
Na content in liver1.61.72.8-0.7-0.70.11.5-1.61.31.7-1.71.41.31.61.4-1.51.20.5
Rb content in liver2.02.54.6-0.7-0.7-1.11.4-1.72.11.6-1.81.71.61.71.9-1.81.91.2
Se content in liver0.60.71.4-0.5-0.50.41.2-1.20.71.1-1.11.00.70.90.7-0.70.4-0.6
Sr content in liver0.70.72.1-1.4-1.4-1.41.0-0.60.50.8-0.30.70.60.0-0.30.3-0.5-0.7
Zn content in liver0.60.73.3-1.5-1.5-1.80.9-0.40.60.3-0.10.40.6-0.3-0.50.6-0.6-0.1
Bone: minimum diameter1.01.94.82.02.02.2-1.91.6-2.0-1.01.1-0.9-0.8-0.4-0.30.1-0.2-1.6
Time in familiar zone, hab. session 10.70.71.6-1.2-1.2-1.20.20.3-0.3-0.20.5-0.4-0.3-0.7-1.01.0-1.3-1.2
Time in novel zone, hab. session 10.80.82.71.21.21.6-0.1-0.30.10.4-0.60.40.40.91.1-1.21.20.6
Total zone transitions, hab. session 11.11.52.71.31.30.4-1.61.5-1.5-1.61.4-1.3-1.0-1.2-1.11.0-0.8-0.5
Total locomotion distance, hab. session 10.10.10.30.60.60.4-0.1-0.1-0.1-0.1-0.20.10.10.20.2-0.30.3-0.1
Locomotion velocity, hab. session 10.00.10.20.40.4-0.1-0.1-0.10.1-0.1-0.20.20.20.10.2-0.30.40.1
Time in familiar zone, hab. session 20.60.71.81.11.10.6-0.70.30.10.1-0.2-0.30.10.71.1-1.11.31.4
Time in novel zone, hab. session 20.70.71.7-0.9-0.9-0.70.10.2-0.5-0.40.6-0.0-0.1-0.9-1.21.2-1.3-1.3
Total zone transitions, hab. session 21.01.32.81.01.0-0.2-1.71.6-1.5-1.51.4-1.1-0.6-1.3-1.00.9-0.6-0.4
Total locomotion distance, hab. session 20.60.81.71.01.00.1-1.31.2-1.1-1.11.0-0.7-0.5-0.9-0.70.5-0.3-0.4
Locomotion velocity, hab. session 20.40.61.10.90.90.2-1.11.0-1.0-1.00.9-0.7-0.5-0.8-0.60.5-0.4-0.4
Novel to familiar place preference ratio0.30.30.50.10.10.30.4-0.50.50.5-0.60.30.70.70.7-0.70.70.6
Novelty place preference0.20.20.40.30.30.60.2-0.40.40.5-0.50.20.50.60.7-0.70.60.5
Time in novel zone, NPP test0.40.40.80.50.50.70.1-0.30.30.5-0.60.20.70.80.9-0.90.90.6
Total zone transitions, NPP test0.81.22.91.71.71.0-1.61.3-1.2-1.21.0-1.1-0.9-0.8-0.50.30.10.5
Total locomotion distance, NPP test0.40.61.81.41.40.7-1.20.9-0.8-0.70.6-0.5-0.3-0.5-0.10.00.40.1
Locomotion velocity, NPP test0.40.51.21.11.10.6-1.00.9-0.8-0.70.7-0.5-0.6-0.7-0.50.4-0.1-0.3
Intraocular pressure0.40.61.51.11.10.4-1.20.8-0.7-0.50.30.20.40.20.7-0.71.10.6
Delta distance traveled before/after self-admin1.51.73.92.02.01.6-1.51.3-1.1-1.01.2-1.5-1.6-0.9-0.60.7-0.7-0.2
Delta ambulatory time before/after self-admin1.01.14.62.12.11.8-1.10.7-0.5-0.30.4-0.9-1.0-0.10.2-0.20.30.4
Parametrial fat weight2.54.915.23.93.93.7-3.02.1-1.8-1.91.4-1.8-1.4-0.40.2-0.30.71.4
Pavlov. Cond. lever latency0.20.20.60.80.8-0.6-0.70.40.3-0.00.1-0.30.10.10.4-0.30.60.4
Pavlov. Cond. magazine entry latency0.30.41.10.80.80.2-0.80.6-0.5-1.00.5-0.8-0.7-0.5-0.30.20.11.0
Pavlov. Cond. change in total contacts0.30.30.60.20.20.0-0.40.4-0.5-0.70.5-0.6-0.8-0.7-0.70.6-0.50.2
Pavlov. Cond. index score0.40.51.10.50.50.2-0.70.7-0.7-1.10.7-0.8-0.9-0.7-0.70.6-0.50.5
Pavlov. Cond. latency score0.30.40.90.40.40.3-0.60.6-0.6-0.90.6-0.7-0.9-0.7-0.60.5-0.50.4
Pavlov. Cond. lever contacts0.10.20.5-0.7-0.70.10.7-0.50.10.2-0.40.40.20.30.0-0.2-0.10.4
Pavlov. Cond. magazine entry number1.11.33.1-1.1-1.1-0.21.5-1.41.21.7-1.31.31.31.21.0-0.90.5-0.7
Pavlov. Cond. intertrial magazine entries0.00.00.1-0.1-0.1-0.1-0.30.2-0.4-0.20.20.20.2-0.1-0.10.1-0.1-0.3
Pavlov. Cond. lever-magazine prob. diff.0.30.30.80.50.50.3-0.50.5-0.5-0.90.5-0.7-0.8-0.5-0.40.3-0.20.8
Pavlov. Cond. response bias0.30.30.90.20.20.1-0.50.5-0.6-1.00.6-0.7-0.7-0.6-0.60.5-0.40.7
Pavlov. Cond. lever latency2.73.77.1-0.1-0.1-2.0-1.31.8-1.3-2.22.2-1.9-1.8-2.5-2.52.7-2.4-1.8
Pavlov. Cond. magazine entry latency0.70.85.01.51.52.2-0.90.4-0.4-0.20.0-0.1-0.20.20.5-0.60.80.7
Pavlov. Cond. change in total contacts1.52.14.60.40.41.30.6-1.10.81.5-1.51.71.51.82.0-2.12.20.7
Pavlov. Cond. index score1.21.56.01.01.02.40.1-0.70.20.9-1.01.00.91.41.5-1.71.70.8
Pavlov. Cond. latency score1.21.57.01.11.12.60.0-0.60.20.8-1.00.90.81.31.5-1.71.61.0
Pavlov. Cond. lever contacts1.11.53.10.20.21.80.6-1.00.51.3-1.31.31.21.61.5-1.71.60.8
Pavlov. Cond. magazine entry number0.70.84.6-1.5-1.5-2.20.7-0.20.40.10.1-0.1-0.1-0.3-0.60.7-1.0-0.6
Pavlov. Cond. intertrial magazine entries0.10.10.7-0.2-0.2-0.20.1-0.0-0.2-0.0-0.0-0.1-0.20.1-0.10.1-0.4-0.9
Pavlov. Cond. lever-magazine prob. diff.1.01.25.61.01.02.40.0-0.60.10.8-0.90.90.81.21.3-1.51.50.6
Pavlov. Cond. response bias1.01.33.50.60.61.90.3-0.70.21.0-1.11.31.11.41.5-1.71.60.6
Time in closed arm before self-admin0.20.20.8-0.4-0.40.0-0.10.4-0.5-0.30.5-0.10.1-0.4-0.40.5-0.7-0.9
Time in closed arm after self-admin0.80.94.3-2.1-2.1-1.70.40.0-0.1-0.20.20.30.6-0.3-0.30.4-0.50.5
Time in open arm before self-admin0.40.41.1-0.4-0.4-0.30.8-1.00.90.7-0.90.50.10.60.4-0.40.40.6
Time in open arm after self-admin1.92.13.31.31.31.50.9-1.51.51.6-1.71.00.51.71.8-1.81.80.9
Bone: periosteal estimation2.24.611.03.33.33.3-2.82.3-2.7-1.81.6-1.5-1.7-0.8-0.60.4-0.3-1.8
Bone: periosteal perimeter3.55.915.73.63.64.0-3.02.5-3.1-2.01.8-1.9-1.9-1.0-0.80.6-0.6-2.3
Bone: post-yield work0.60.91.6-0.2-0.20.90.8-0.90.30.9-1.10.91.11.31.1-1.21.10.8
Progressive ratio test 1 active lever presses0.10.10.40.30.30.4-0.0-0.00.10.2-0.20.40.60.40.4-0.50.60.2
Progressive ratio test 1 breakpoint0.40.51.0-0.0-0.00.10.5-0.60.70.7-0.70.91.00.80.9-0.90.90.3
Progressive ratio test 1 inactive lever presses0.50.61.40.70.70.90.2-0.50.60.8-0.70.70.41.00.9-1.01.20.1
Progressive ratio test 2 active lever presses0.40.41.31.11.11.1-0.60.4-0.2-0.10.10.00.60.30.3-0.50.70.5
Progressive ratio test 2 breakpoint0.40.51.51.21.21.2-0.50.2-0.10.1-0.10.20.70.50.6-0.70.90.6
Progressive ratio test 2 inactive lever presses0.60.72.60.80.81.6-0.1-0.30.20.7-0.60.60.61.01.0-1.11.20.5
Incentive Sensitization - Responses0.40.41.81.01.01.3-0.40.1-0.10.0-0.20.20.60.50.4-0.70.80.8
Incentive Sensitization - Breakpoint0.50.52.21.11.11.5-0.40.0-0.10.1-0.20.10.60.60.5-0.70.90.8
Sum of active levers in priming session hrs 5-60.60.61.4-0.1-0.10.11.0-1.21.01.2-1.10.60.10.90.8-0.70.60.2
Progressive ratio1.41.62.6-1.3-1.3-0.51.6-1.41.21.5-1.41.61.51.21.1-1.11.00.4
Food seeking constrained by brief footshock2.02.44.0-0.5-0.5-0.31.3-1.61.61.6-1.71.81.91.81.8-1.92.01.6
Seeking ratio, punishment vs. effort0.10.20.50.70.7-0.0-0.70.4-0.2-0.50.3-0.3-0.1-0.2-0.10.10.20.2
Retroperitoneal fat weight5.818.936.45.65.64.6-6.05.5-5.3-5.14.6-4.5-3.8-3.3-2.52.2-1.7-0.1
Reaction time number correct0.50.83.41.91.91.2-1.10.6-0.3-0.40.3-0.5-0.5-0.00.3-0.30.80.4
Reaction time mean minus median0.20.31.60.90.91.2-0.30.2-0.20.10.1-0.5-0.40.00.2-0.0-0.10.1
Reaction time mean minus median AUC0.60.81.61.01.01.3-0.90.9-0.9-0.80.9-1.2-1.0-0.8-0.70.8-0.9-0.2
Reaction time num false alarms0.10.20.90.10.10.50.2-0.20.10.2-0.30.30.60.40.5-0.50.51.0
Reaction time num false alarms AUC0.10.10.70.10.10.60.0-0.0-0.2-0.1-0.00.00.30.00.1-0.10.10.8
Reaction time trials correct on left0.50.83.41.91.91.2-1.10.6-0.3-0.40.3-0.5-0.5-0.00.3-0.30.80.4
Reaction time trials on left0.50.83.41.81.81.2-1.10.7-0.4-0.40.4-0.5-0.5-0.10.3-0.20.80.4
Reaction time mean0.30.41.10.10.10.3-0.20.5-0.6-0.40.6-0.8-0.6-0.7-0.80.8-1.1-0.5
Reaction time mean AUC0.10.10.7-0.3-0.3-0.00.20.0-0.2-0.10.2-0.4-0.2-0.3-0.50.5-0.8-0.3
Median of all reaction times0.50.72.0-0.1-0.10.1-0.30.6-0.8-0.70.8-1.0-0.9-1.0-1.21.2-1.4-0.7
Reaction time omissions0.00.10.30.00.00.5-0.10.2-0.6-0.10.1-0.10.10.0-0.10.0-0.3-0.0
Reaction time false alarm rate0.30.41.0-1.0-1.0-0.30.8-0.60.20.4-0.50.60.90.40.3-0.30.00.6
Reaction time premature initiation rate2.02.75.01.51.50.9-1.71.7-1.4-1.61.8-2.1-2.2-1.9-1.71.8-1.5-0.6
Reaction time premature initiations3.04.37.02.72.71.6-2.42.2-1.7-2.02.1-2.5-2.6-2.0-1.71.8-1.2-0.5
Std. dev. reaction times0.50.72.21.11.11.5-0.90.9-0.9-0.60.7-1.0-0.7-0.6-0.40.5-0.6-0.2
Reaction time trials completed0.50.83.41.81.81.2-1.10.7-0.4-0.40.4-0.5-0.5-0.10.3-0.20.80.4
Reaction time trials AUC0.50.83.51.91.91.1-1.10.7-0.3-0.40.4-0.5-0.4-0.10.3-0.30.80.3
Run reversals in cocaine runway, females1.71.63.01.11.10.7-1.31.3-1.2-1.41.4-1.6-1.7-1.4-1.31.3-1.3-0.4
Run reversals in cocaine runway, males1.61.52.7-1.6-1.6-1.21.5-1.41.21.1-1.31.21.21.10.9-1.00.61.0
Latency to leave start box in cocaine runway0.10.20.6-0.5-0.5-0.10.6-0.50.20.7-0.40.2-0.20.20.10.1-0.2-0.8
Latency to leave start box in cocaine runway, F0.40.41.2-1.1-1.1-0.80.4-0.1-0.20.20.2-0.1-0.4-0.4-0.50.7-1.0-1.0
Latency to leave start box in cocaine runway, M0.20.20.40.50.50.60.1-0.30.30.3-0.40.30.10.60.6-0.50.60.1
Std. dev. time between licks in bursts1.61.93.4-0.2-0.20.51.1-1.41.11.8-1.71.81.41.81.7-1.91.80.4
Total sessions with >9 infusions2.02.24.01.91.91.4-2.01.8-1.4-1.61.6-1.6-1.7-1.2-1.01.0-0.7-0.4
Short access day 1 total inactive lever presses0.60.62.41.51.51.6-1.00.6-0.5-0.10.4-0.6-0.80.00.1-0.10.2-0.1
Short access day 10 total inactive lever presses0.10.20.70.70.70.8-0.40.3-0.20.10.1-0.00.00.20.1-0.20.4-0.3
Short access day 1 total infusions0.30.30.90.90.90.7-0.80.5-0.2-0.20.3-0.6-0.8-0.1-0.1-0.00.10.1
Short access day 10 total infusions0.60.71.30.30.30.60.6-0.80.80.9-0.91.00.81.00.9-1.11.10.0
Short access total infusions0.50.51.50.80.80.9-0.0-0.40.70.6-0.60.50.30.80.9-1.01.20.5
Short access day 1 locomotion0.20.20.70.70.70.9-0.1-0.10.40.2-0.3-0.0-0.40.50.6-0.60.60.3
Short access day 10 total locomotion2.02.34.30.80.80.8-1.31.5-1.5-1.61.6-1.9-2.1-1.6-1.71.7-1.8-0.9
Short access total locomotion1.01.01.60.40.40.2-0.91.1-1.0-1.21.2-1.2-1.3-1.2-1.21.2-1.1-0.8
One hour access (0.3 mA shock)2.42.86.92.52.52.6-0.2-0.60.90.9-1.10.40.61.61.8-2.02.31.9
Compulsive drug intake0.80.81.40.70.70.90.5-1.00.81.0-1.10.80.41.11.1-1.21.20.8
One hour access (shock baseline)0.40.41.51.21.21.2-0.80.5-0.4-0.40.3-0.5-0.3-0.00.0-0.20.30.4
Social response proportion3.84.15.81.81.81.0-2.32.4-2.3-2.42.4-2.3-1.7-2.2-2.12.1-1.8-0.8
Social responses1.41.96.22.52.52.3-1.71.3-1.2-0.90.9-1.1-0.4-0.40.0-0.10.31.0
Social time1.41.93.41.51.51.0-1.61.6-1.4-1.61.5-1.8-1.4-1.3-1.11.2-1.10.2
Soleus weight4.513.320.14.24.22.7-4.54.2-3.8-4.23.9-3.8-4.3-3.6-3.03.0-2.3-1.5
Bone: stiffness0.60.94.90.50.51.9-0.40.5-1.6-0.40.4-0.1-0.3-0.2-0.60.4-0.7-2.2
Tibialis anterior weight0.20.82.50.10.1-0.80.4-0.71.20.6-0.80.60.80.81.1-1.01.41.6
Time to tail flick, vehicle, before self-admin1.01.03.41.81.81.8-1.20.8-0.4-0.60.6-1.0-1.0-0.3-0.00.10.20.4
Time to tail flick, vehicle, after self-admin0.80.91.81.11.11.2-0.80.7-0.7-0.70.7-1.0-1.4-0.9-0.80.9-0.7-1.2
Time to tail flick, test, before self-admin2.72.63.80.90.9-0.0-1.51.8-1.7-1.91.9-1.8-1.5-1.9-2.02.0-1.9-1.0
Time to tail flick, test, after self-admin0.70.72.41.21.21.6-1.10.9-1.0-0.40.7-0.7-0.8-0.4-0.10.2-0.1-0.1
Delta time to tail flick, vehicle, before/after SA0.10.11.0-0.3-0.3-0.30.3-0.1-0.10.2-0.00.20.1-0.1-0.20.2-0.2-1.0
Delta time to tail flick, test, before/after SA0.30.31.50.60.61.2-0.40.0-0.00.3-0.20.10.00.40.7-0.60.70.5
Tibia length1.95.39.41.81.82.0-2.42.4-3.1-2.42.4-2.4-2.5-2.2-2.32.0-2.3-2.2
Ambulatory time before self-admin2.62.75.7-0.7-0.7-0.9-1.11.7-1.7-1.81.9-1.6-1.3-2.1-2.32.2-2.4-0.8
Ambulatory time after self-admin4.34.87.71.51.51.2-2.02.2-2.1-2.02.4-2.8-2.8-2.5-2.52.5-2.6-1.3
Bone: tissue strength0.60.61.0-1.0-1.0-0.90.7-0.70.60.5-0.70.90.90.70.6-0.60.50.6
Total heroin consumption0.30.31.20.40.40.2-0.30.10.20.2-0.20.50.80.60.7-0.81.10.8
Bone: trabecular number0.30.41.21.01.01.1-0.1-0.30.10.4-0.50.40.50.70.8-0.80.9-0.1
Bone: trabecular spacing0.30.30.7-0.7-0.7-0.70.6-0.60.70.4-0.50.30.60.50.5-0.50.40.8
Bone: trabecular thickness2.63.111.53.23.23.4-2.01.4-1.5-1.10.9-1.2-1.6-0.40.0-0.10.2-0.7
Bone: trabecular tissue density0.50.71.70.00.01.0-0.20.5-1.1-0.40.6-0.8-1.1-0.7-0.90.9-1.3-1.3
Water consumed over 24 hours1.51.84.31.31.30.7-1.31.4-1.5-1.11.4-1.0-1.0-1.5-1.41.5-1.1-2.1
Number of responses in last shaping day0.20.21.0-0.3-0.3-1.0-0.40.50.1-0.60.5-0.4-0.4-0.5-0.20.4-0.20.2