Hub : Genes

Vti1a

vesicle transport through interaction with t-SNAREs 1A

chr1:264361538–264667171 (+)

Vti1a RatGTEx page

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 LHb intron excision ratio chr1_264431674_264436174 0.14 0.11 7.1e-03 0.07 0.04 0.1 0.08 8.0e-03 3.4e-02 2.5e-03 5.3e-03
2 Liver mRNA stability Vti1a 0.03 0.02 9.7e-04 0.02 0.02 0.01 0.02 3.0e-03 2.2e-03 8.4e-03 4.3e-03
3 Adipose alternative polyA XM_039090083.2 0.08 0.06 2.8e-04 0.03 0.02 0.02 0.03 9.4e-05 1.5e-03 9.2e-04 1.6e-04
4 IC alternative polyA XM_039090066.2 0.09 0.08 6.2e-03 0.06 0.04 0.04 0.04 1.3e-03 1.2e-02 1.1e-02 1.0e-02
5 Adipose alternative polyA XM_039090083.2 0.06 0.05 2.8e-03 0.03 0.02 0.02 0.03 5.3e-04 3.8e-03 3.3e-03 5.6e-04
6 IL gene expression Vti1a 0.28 0.19 2.4e-03 0.1 0.09 0.06 0.1 2.2e-03 3.8e-03 1.3e-02 2.8e-03
7 PL gene expression Vti1a 0.08 0.06 8.4e-08 0.08 0.07 0.04 0.07 7.1e-09 7.2e-08 3.3e-05 1.5e-08
8 BLA mRNA stability Vti1a 0.11 0.07 4.1e-05 0.08 0.07 0.04 0.08 4.3e-05 1.1e-04 4.5e-03 5.1e-05
9 pVTA gene expression Vti1a 0.05 0.04 1.4e-03 0.01 0.02 0.02 0.02 2.3e-02 6.1e-03 1.5e-02 1.3e-02
10 OFC mRNA stability Vti1a 0.21 0.16 5.9e-03 0.01 0.02 0.05 0.05 1.5e-01 8.8e-02 2.1e-02 3.1e-02
11 IC gene expression Vti1a 0.12 0.08 2.9e-04 0.07 0.05 0.08 0.07 9.2e-04 4.7e-03 4.0e-04 6.3e-04
12 NAcc gene expression Vti1a 0.04 0.03 5.2e-06 0.03 0.04 0.03 0.03 5.9e-06 2.9e-06 2.8e-05 6.2e-06
13 Brain gene expression Vti1a 0.06 0.04 2.0e-04 0.01 0.03 0.03 0.02 1.9e-02 9.4e-04 1.7e-03 5.4e-03
14 BLA gene expression Vti1a 0.07 0.06 3.9e-03 0.04 0.03 0.04 0.02 1.9e-03 9.0e-03 4.8e-03 2.8e-02
15 NAcc mRNA stability Vti1a 0.04 0.03 4.8e-05 0.02 0.03 0.03 0.03 1.9e-04 4.7e-05 3.5e-05 6.6e-05
16 PL mRNA stability Vti1a 0.08 0.05 2.1e-06 0.03 0.05 0.05 0.05 1.1e-04 2.2e-06 3.8e-06 2.4e-06
17 Brain mRNA stability Vti1a 0.14 0.07 1.8e-11 0.11 0.13 0.12 0.12 1.1e-10 6.7e-12 2.6e-11 1.7e-11
18 Liver intron excision ratio chr1_264540942_264541907 0.03 0.02 4.0e-03 0.02 0.01 0.02 0.02 4.1e-03 3.6e-02 2.6e-03 4.0e-03

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18
Bone: apparent density0.81.35.6-2.41.31.6-1.61.90.60.60.6-1.20.5-1.3-0.1-0.80.7-1.0-0.6-0.5-0.1
Area under the delay curve0.70.81.9-0.90.31.0-0.91.4-0.4-0.4-0.7-1.3-0.3-1.2-0.7-1.1-0.1-1.1-1.0-0.9-0.6
BMI with tail4.013.859.0-7.76.41.9-1.92.05.04.74.7-0.04.20.63.41.63.61.82.02.43.2
BMI without tail2.26.729.8-5.54.51.4-1.31.03.93.23.10.22.50.32.61.31.81.01.72.02.3
Body weight4.117.979.1-8.97.42.9-2.92.85.55.55.1-0.44.80.23.71.54.01.61.92.53.4
Weight adjusted by age2.33.58.5-2.92.9-0.10.1-0.22.72.52.50.91.81.02.21.51.21.51.71.92.0
Bone surface0.30.52.9-1.71.00.6-0.60.81.00.70.7-0.30.6-0.50.3-0.00.8-0.30.00.10.3
Bone volume1.11.99.3-3.12.21.4-1.41.61.61.61.6-0.71.4-0.70.7-0.01.5-0.20.10.30.7
Breakpoint value in progressive ratio session1.41.73.3-0.90.01.8-1.81.6-0.7-0.8-0.9-1.7-0.8-1.6-1.2-1.5-0.8-1.3-1.5-1.4-1.3
Number of licking bursts0.71.22.6-1.00.01.5-1.51.6-0.2-0.7-1.0-1.4-0.6-1.3-0.9-1.2-0.4-1.1-1.2-1.1-1.0
Context. condit. distance diff. score0.70.82.30.7-0.1-1.31.3-1.50.40.30.31.30.00.90.81.10.00.81.11.00.8
Locomotion velocity, session 12.02.13.91.5-2.00.3-0.30.4-1.6-2.0-1.8-1.0-2.0-1.1-1.7-1.4-1.6-1.4-1.4-1.5-1.6
Locomotion distance, session 10.20.31.00.6-0.5-1.01.0-1.00.2-0.10.10.7-0.30.50.30.5-0.10.30.50.40.3
Locomotion velocity, session 21.31.53.90.9-0.3-2.02.0-2.00.70.30.41.70.31.41.01.40.51.21.41.31.0
Locomotion distance, session 20.60.82.8-1.71.50.2-0.20.31.21.31.40.20.90.21.00.50.90.30.60.71.0
Locomotion velocity, session 30.20.30.70.00.2-0.50.5-0.80.50.30.30.7-0.00.40.60.70.20.40.70.70.6
Locomotion distance, session 31.81.93.0-0.20.8-1.41.4-1.61.31.51.51.60.81.51.61.60.21.41.71.61.6
Stereotopy head waving bouts, day 30.00.00.3-0.20.20.5-0.50.3-0.2-0.1-0.0-0.2-0.00.1-0.0-0.1-0.00.3-0.1-0.1-0.1
Stereotopy head waving duration, day 31.01.22.50.9-1.20.8-0.80.5-1.2-1.6-1.5-0.9-1.4-0.8-1.2-1.1-1.0-0.8-1.1-1.2-1.3
Locomotion velocity, session 70.00.10.2-0.40.10.3-0.30.20.20.20.1-0.1-0.1-0.4-0.0-0.10.1-0.4-0.1-0.1-0.1
Locomotion distance, session 70.30.30.80.20.0-0.90.9-0.80.40.50.60.70.20.50.50.70.30.30.70.60.6
Stereotopy head waving bouts, day 70.10.10.3-0.30.00.6-0.60.30.2-0.2-0.4-0.3-0.0-0.3-0.2-0.2-0.0-0.1-0.2-0.2-0.3
Stereotopy head waving duration, day 70.30.41.4-0.90.21.2-1.20.90.3-0.3-0.5-0.7-0.0-0.7-0.3-0.50.1-0.5-0.5-0.4-0.5
Locomotion velocity, session 80.40.52.31.5-1.2-0.80.8-1.1-0.5-0.8-0.60.6-0.70.4-0.20.2-0.30.20.10.0-0.2
Locomotion distance, session 80.60.81.90.30.1-1.31.3-1.40.70.50.71.20.10.80.91.10.40.61.11.00.9
Degree of sensitization distance1.71.82.70.7-1.30.9-0.91.1-1.3-1.6-1.6-1.3-1.1-1.5-1.6-1.5-0.5-1.6-1.6-1.5-1.6
Degree of sensitization stereotypy0.30.30.8-0.50.00.9-0.90.80.1-0.3-0.5-0.7-0.2-0.7-0.4-0.6-0.2-0.7-0.6-0.5-0.5
Conditioned locomotion0.10.10.40.40.1-0.20.2-0.60.10.40.30.40.30.50.30.40.30.60.40.30.3
Cocaine response after cond. corrected0.60.72.51.6-0.8-1.21.2-1.6-0.2-0.1-0.51.0-0.50.80.30.6-0.90.50.60.50.2
Cocaine response after cond. not corrected0.80.94.42.1-1.4-1.21.2-1.5-0.7-0.5-0.80.8-0.80.6-0.20.3-1.00.30.20.1-0.2
Cocaine response before conditioning0.50.61.20.7-1.10.4-0.40.5-1.1-0.9-0.8-0.7-0.6-0.5-1.1-0.9-0.1-0.5-1.0-1.0-1.1
Saline control response0.30.51.81.3-0.9-1.31.3-0.9-0.5-0.5-0.40.7-0.30.5-0.00.4-0.10.10.30.20.1
Bone: connectivity density0.10.10.4-0.2-0.2-0.10.10.3-0.0-0.3-0.3-0.2-0.3-0.6-0.2-0.20.1-0.6-0.2-0.2-0.2
Bone: cortical apparent density3.34.411.61.8-0.5-3.43.4-3.30.90.80.82.80.72.61.62.30.42.22.32.01.7
Bone: cortical area2.33.518.8-4.32.82.4-2.42.32.51.61.6-1.21.2-1.30.7-0.31.1-0.8-0.10.20.4
Bone: cortical porosity0.60.61.1-0.1-0.31.0-1.00.8-0.8-0.7-0.8-0.9-0.6-1.0-0.7-0.9-0.2-1.0-0.8-0.8-0.7
Bone: cortical porosity1.11.22.6-0.80.11.6-1.61.5-0.6-0.6-0.8-1.4-0.6-1.5-0.9-1.2-0.3-1.4-1.1-1.0-0.9
Bone: cortical thickness1.32.29.7-3.12.41.0-1.01.02.41.81.8-0.11.4-0.21.30.61.30.00.70.91.1
Bone: cortical thickness1.51.84.0-2.01.90.0-0.0-0.32.01.51.80.71.50.81.41.11.71.31.11.31.4
Bone: cortical tissue density3.24.411.72.0-0.6-3.43.4-3.30.80.70.72.80.62.61.52.30.32.22.22.01.6
Condit. Reinf. active minus inactive responses0.60.63.70.3-0.60.3-0.30.3-0.5-0.9-0.8-0.6-1.5-0.6-0.6-0.7-1.9-0.8-0.6-0.7-0.6
Condit. Reinf. active-inactive response ratio0.70.83.90.7-1.0-0.0-0.00.1-0.7-1.1-1.0-0.5-1.6-0.5-0.8-0.6-2.0-0.8-0.6-0.7-0.7
Condit. Reinf. active responses0.60.72.8-0.60.01.0-1.01.0-0.2-0.4-0.4-1.0-1.1-1.0-0.6-0.9-1.7-1.0-0.8-0.8-0.5
Condit. Reinf. inactive responses0.60.82.2-1.10.51.5-1.51.30.10.0-0.1-1.1-0.3-1.0-0.5-0.9-0.6-0.9-0.8-0.7-0.5
Incentive salience index mean0.91.15.20.9-1.20.1-0.10.2-0.9-1.2-1.1-0.7-1.8-0.7-1.0-0.9-2.3-1.0-0.8-0.9-0.9
Condit. Reinf. lever presses0.71.02.51.0-1.30.2-0.20.3-1.1-1.1-1.1-0.8-1.4-0.7-1.2-1.0-1.6-1.0-1.0-1.1-1.1
Condit. Reinf. active minus inactive responses5.16.510.9-0.2-1.52.6-2.62.5-1.3-2.2-2.7-2.8-2.9-3.0-2.5-2.7-3.3-3.2-2.7-2.6-2.7
Condit. Reinf. active-inactive response ratio3.74.29.30.4-1.61.6-1.61.6-1.2-2.1-2.5-2.0-2.6-2.2-2.1-2.1-3.1-2.5-2.0-2.1-2.2
Condit. Reinf. active responses4.36.09.9-1.1-0.82.9-2.92.9-0.9-1.7-2.1-2.9-2.3-3.1-2.3-2.7-2.6-3.2-2.6-2.5-2.5
Condit. Reinf. inactive responses0.91.12.7-1.10.21.6-1.61.6-0.2-0.2-0.4-1.4-0.5-1.5-0.8-1.2-0.5-1.4-1.1-1.0-0.9
Condit. Reinf. lever presses2.33.25.6-0.9-0.71.8-1.82.2-0.6-1.5-1.8-2.1-1.7-2.3-1.8-2.0-1.7-2.4-2.0-1.9-1.8
Condit. Reinf. lever reinforcers received4.15.79.7-0.9-0.92.7-2.72.8-0.9-1.7-2.0-2.8-2.3-3.0-2.3-2.6-2.7-3.1-2.5-2.5-2.4
Conditioned reinforcement - actives0.61.02.10.1-0.50.8-0.81.2-0.8-0.9-0.9-1.1-1.0-1.2-1.0-1.1-1.1-1.4-1.1-1.1-1.0
Conditioned reinforcement - inactives0.40.51.4-0.90.41.1-1.11.2-0.2-0.2-0.2-1.0-0.5-0.8-0.4-0.7-0.6-0.7-0.7-0.6-0.5
Conditioned locomotion0.30.31.3-0.10.2-0.80.9-0.00.40.40.40.51.00.60.40.51.20.50.40.50.5
Patch foraging indifference point 0 sec0.71.36.4-2.52.21.2-1.11.11.41.31.1-0.31.2-0.11.00.30.70.20.40.60.9
Patch foraging indifference point AUC1.31.94.7-0.6-0.12.0-2.02.2-1.2-0.7-0.7-1.9-0.4-1.6-1.4-1.70.0-1.4-1.7-1.6-1.3
Delay disc. indifference point, 0s delay0.40.42.4-1.51.10.6-0.60.60.60.50.6-0.20.7-0.20.50.11.00.20.20.30.4
Delay disc. indifference point, 16s delay1.01.11.8-0.1-0.41.1-1.01.2-0.9-0.9-1.2-1.3-0.8-1.2-1.1-1.3-0.4-1.3-1.3-1.2-1.1
Delay disc. indifference point, 2s delay0.00.00.3-0.20.2-0.20.2-0.00.10.00.10.10.40.10.10.10.50.20.10.10.2
Delay disc. indifference point, 24s delay2.02.34.4-0.6-0.21.8-1.82.1-1.1-1.0-1.5-2.1-0.8-1.7-1.5-1.9-0.4-1.6-1.9-1.7-1.5
Delay disc. indifference point, 4s delay0.40.41.0-0.1-0.10.6-0.60.8-0.4-0.6-0.6-0.7-0.7-0.9-0.5-0.7-0.6-1.0-0.6-0.6-0.5
Delay disc. indifference point, 8s delay1.11.24.5-2.11.11.5-1.41.9-0.00.1-0.2-1.60.1-1.4-0.5-1.10.2-1.0-1.0-0.9-0.5
Indifference point function ln k0.30.52.20.6-0.2-0.90.9-1.50.40.10.10.9-0.10.70.50.8-0.30.60.80.70.5
Indifference point function log k0.30.52.20.6-0.2-0.90.9-1.50.40.10.10.9-0.10.70.50.8-0.30.60.80.70.5
Patch foraging total patch changes 0 sec0.71.36.4-2.52.11.4-1.41.41.21.10.9-0.61.0-0.40.7-0.00.6-0.00.20.30.7
Patch foraging total patch changes 12 sec0.81.03.3-1.40.71.7-1.71.8-0.1-0.1-0.3-1.3-0.0-1.2-0.5-1.0-0.1-1.0-0.9-0.8-0.5
Patch foraging total patch changes 18 sec1.82.88.5-2.21.12.8-2.82.9-0.3-0.2-0.3-2.2-0.0-1.9-0.9-1.70.1-1.5-1.5-1.3-0.9
Patch foraging total patch changes 24 sec2.13.510.0-1.60.43.2-3.22.8-0.9-0.9-1.0-2.5-0.7-2.2-1.5-2.1-0.6-1.7-2.0-1.9-1.5
Patch foraging total patch changes 6 sec1.21.89.2-3.02.21.8-1.82.21.21.10.9-1.11.0-0.90.5-0.40.8-0.6-0.20.00.5
Patch foraging time to switch 0 sec0.20.41.31.1-0.7-1.11.1-0.90.0-0.4-0.40.8-0.40.50.20.5-0.4-0.00.50.40.3
Patch foraging water rate 0 sec0.10.31.2-1.10.90.6-0.60.40.30.60.7-0.30.5-0.00.2-0.10.50.5-0.00.10.2
Patch foraging water rate 12 sec0.10.31.5-1.20.90.8-0.80.70.10.30.5-0.60.2-0.40.1-0.30.30.0-0.2-0.10.1
Patch foraging water rate 18 sec0.40.71.8-1.11.1-0.30.3-0.40.81.21.30.50.90.60.90.70.80.90.70.80.9
Patch foraging water rate 24 sec0.71.05.1-2.31.70.8-0.70.31.11.21.0-0.20.90.10.80.31.00.90.40.50.7
Patch foraging water rate 6 sec0.81.12.3-0.80.9-0.90.9-0.81.10.91.01.01.31.11.11.11.51.41.01.11.0
Seeking ratio, delayed vs. immediate footshock0.00.00.20.4-0.2-0.10.1-0.10.0-0.2-0.30.30.10.20.10.20.50.00.10.1-0.0
Distance traveled before self-admin3.34.47.50.70.5-2.72.7-2.71.51.51.72.71.62.52.02.51.42.32.42.32.1
Distance traveled after self-admin3.03.75.2-0.41.2-1.91.9-1.71.61.81.92.12.12.12.02.22.32.12.12.12.1
Extensor digitorum longus weight0.20.61.9-1.41.31.2-1.21.10.60.80.8-0.50.7-0.50.4-0.20.7-0.3-0.10.10.4
Bone: elastic displacement0.10.20.6-0.30.10.4-0.40.4-0.0-0.1-0.3-0.4-0.5-0.6-0.2-0.4-0.6-0.8-0.3-0.3-0.2
Bone: elastic work1.62.04.0-1.61.8-0.70.7-0.72.01.81.71.11.41.01.71.41.31.11.51.61.7
Bone: endosteal estimation0.71.57.0-2.61.71.9-1.91.61.21.00.9-1.10.8-0.80.2-0.50.7-0.3-0.4-0.20.0
Bone: endosteal perimeter1.12.313.2-3.62.31.6-1.61.52.41.51.3-0.71.3-0.50.7-0.01.20.10.10.40.4
Epididymis fat weight3.110.657.4-7.65.34.5-4.54.13.33.12.9-2.52.1-2.11.2-0.91.6-0.8-0.40.10.9
Delta time in closed arm before/after self-admin1.21.21.9-0.00.6-1.21.2-0.80.91.31.41.21.01.41.11.20.61.31.21.11.2
Delta time in open arm before/after self-admin1.11.12.5-1.10.21.6-1.51.4-0.5-0.8-0.8-1.5-0.4-1.4-0.9-1.2-0.1-1.0-1.2-1.1-0.9
Diff in mean of infusions in LGA sessions0.60.82.71.5-1.3-0.20.1-0.5-0.8-0.9-0.9-0.1-1.5-0.4-0.7-0.4-1.6-0.7-0.4-0.6-0.7
Delay discount exponential model param0.70.82.20.9-0.3-1.11.0-1.50.40.40.71.30.31.20.71.10.11.11.00.90.7
Extinction: sum of active levers before priming2.02.23.30.3-1.01.5-1.51.4-1.6-1.4-1.5-1.7-1.2-1.7-1.7-1.8-0.8-1.5-1.8-1.8-1.7
Active lever presses in extinction session 60.20.20.7-0.80.40.6-0.60.60.10.20.1-0.40.4-0.2-0.1-0.30.40.0-0.3-0.2-0.1
Bone: final force0.61.05.2-2.31.50.9-0.90.81.81.11.3-0.21.0-0.20.60.21.00.20.30.40.5
Bone: final moment0.81.36.7-2.61.71.1-1.11.01.91.31.5-0.31.1-0.30.70.21.10.10.30.50.6
Food consumed during 24 hour testing period0.20.20.5-0.20.3-0.50.5-0.70.60.5-0.00.5-0.10.30.60.6-0.20.30.60.60.5
Glucose1.62.54.6-1.72.0-0.60.6-0.62.12.01.81.12.01.41.81.51.61.81.51.61.8
Heart weight0.81.26.8-2.61.90.9-0.90.91.71.41.3-0.20.4-0.20.90.3-0.4-0.00.50.60.8
Delay discount hyperbolic model param0.50.51.50.9-0.4-0.80.8-1.20.30.20.51.10.20.90.50.80.10.90.80.70.5
Intermittent access intake day 1-15 change0.30.74.1-2.01.51.3-1.30.00.70.70.7-0.50.5-0.30.5-0.00.30.70.10.20.3
Intermittent access intake escalation0.30.73.9-2.01.51.3-1.30.20.60.70.7-0.50.5-0.40.5-0.10.30.50.00.10.2
Intermittent access intake escalation 20.30.42.0-1.41.11.0-1.0-0.00.50.40.4-0.40.4-0.30.3-0.10.50.6-0.00.10.1
Intermitt. access day 1 inactive lever presses0.52.15.4-2.10.92.3-2.32.3-0.3-0.2-0.3-2.0-0.2-1.7-0.9-1.50.1-1.2-1.4-1.2-1.1
Intermitt. access day 15 inactive lever presses0.30.61.5-0.5-0.00.9-0.90.9-0.4-0.3-0.3-0.9-0.8-0.9-0.6-0.8-1.2-1.0-0.7-0.7-0.7
Intermitt. access escalation Index0.40.61.7-0.30.6-0.70.8-0.60.50.60.40.71.00.80.80.81.30.90.70.80.9
Intermittent access day 1 total infusions0.50.82.0-0.70.01.1-1.11.4-0.5-0.4-0.5-1.2-0.6-1.1-0.8-1.1-0.6-0.9-1.0-1.0-0.8
Intermittent access day 15 total infusions0.50.72.4-1.30.61.5-1.51.0-0.1-0.1-0.2-1.1-0.5-1.0-0.4-0.8-0.7-0.4-0.7-0.7-0.6
Intermittent access terminal intake (last 3 days)0.20.30.9-0.90.41.0-0.90.5-0.0-0.1-0.1-0.7-0.2-0.6-0.2-0.5-0.2-0.1-0.5-0.4-0.3
Intermittent access total infusions0.60.81.9-1.20.51.4-1.31.4-0.3-0.2-0.2-1.2-0.3-1.1-0.6-1.0-0.3-0.5-0.9-0.8-0.7
Intermittent access day 1 locomotion0.40.50.9-0.50.7-0.70.80.00.90.80.80.60.60.50.80.70.40.30.80.80.8
Intermittent access day 15 total locomotion0.40.84.3-2.11.60.7-0.70.71.01.00.9-0.30.9-0.30.60.11.00.20.20.40.5
Intermittent access total locomotion0.91.11.8-1.01.1-0.60.6-0.61.31.41.30.81.30.81.11.01.31.01.01.11.1
Intermittent access standard deviation0.40.92.6-1.20.51.6-1.61.4-0.2-0.1-0.1-1.3-0.3-1.0-0.6-1.0-0.4-0.5-0.9-0.8-0.7
Left kidney weight2.511.420.2-4.24.5-1.11.1-0.74.44.34.12.33.82.44.03.23.42.83.43.63.9
Right kidney weight2.712.225.3-5.05.0-0.40.4-0.54.84.64.32.13.62.24.23.13.02.83.43.63.9
Cocaine induced anxiety0.91.24.52.1-1.1-2.02.0-1.4-0.3-0.2-0.11.50.21.20.31.00.40.50.80.70.5
Post-drug Anxiety0.00.10.20.2-0.1-0.40.4-0.1-0.1-0.1-0.20.20.30.20.10.20.50.10.10.10.1
Baseline Anxiety1.51.75.4-1.90.82.3-2.31.6-0.2-0.3-0.5-1.9-0.3-1.5-0.8-1.4-0.3-0.7-1.3-1.2-1.0
Tail length0.10.41.3-1.21.00.9-1.00.70.70.60.2-0.30.0-0.60.40.0-0.2-0.60.20.20.2
Length with tail0.62.811.2-3.33.01.4-1.51.32.02.31.8-0.21.9-0.11.50.61.60.40.81.01.3
Length without tail1.75.424.2-4.94.02.4-2.52.52.42.72.4-1.02.7-0.51.40.12.70.30.30.71.3
LgA early post infusion interval0.10.20.50.7-0.60.2-0.2-0.0-0.6-0.4-0.5-0.2-0.3-0.1-0.5-0.3-0.4-0.0-0.4-0.4-0.5
LgA late post infusion interval1.62.03.10.9-1.21.4-1.41.2-1.8-1.4-1.5-1.5-1.0-1.3-1.7-1.6-0.8-1.1-1.7-1.7-1.7
LgA early loading1.73.15.60.5-1.11.7-1.71.6-1.6-1.5-1.5-2.0-1.9-2.0-1.9-2.0-2.0-2.4-1.9-2.0-1.8
LgA late loading0.10.20.6-0.70.70.0-0.0-0.30.80.50.60.2-0.00.20.60.4-0.60.20.50.50.6
LgA early average infusions1.41.73.50.9-1.20.8-0.80.9-1.3-1.4-1.2-1.1-1.7-1.3-1.4-1.3-1.9-1.7-1.3-1.4-1.3
LgA late average infusions0.40.52.6-1.61.30.4-0.40.41.30.70.90.00.30.00.80.4-0.00.10.50.60.7
LgA early timeout0.20.20.6-0.60.20.7-0.70.80.1-0.2-0.1-0.6-0.3-0.6-0.3-0.5-0.4-0.6-0.4-0.4-0.2
LgA late timeout1.62.13.9-1.51.5-0.70.7-0.92.01.61.81.21.31.31.71.51.01.71.61.61.6
LgA early titration0.60.81.30.2-0.60.9-0.90.9-0.7-0.9-1.0-1.0-0.9-1.1-1.0-1.1-0.7-1.1-1.0-1.1-1.0
LgA late titration0.50.73.5-1.91.50.6-0.60.21.50.81.10.10.50.20.90.40.20.50.60.70.8
LgA total infusion0.20.21.1-1.10.60.7-0.70.60.50.00.3-0.5-0.2-0.50.0-0.3-0.3-0.3-0.2-0.10.0
Times rat made contact with spout0.60.72.1-1.41.40.2-0.20.40.91.10.90.11.00.20.80.51.30.50.50.60.9
Lifetime Intake0.81.02.4-1.40.51.5-1.51.4-0.3-0.3-0.3-1.4-0.4-1.3-0.7-1.1-0.4-0.7-1.0-0.9-0.8
Liver weight, left1.72.815.5-3.92.71.7-1.71.72.31.61.6-0.81.6-0.40.90.01.70.20.20.50.9
Liver weight, right4.78.220.6-4.54.30.4-0.40.43.93.73.61.03.71.42.92.03.62.22.12.42.8
Locomotor activity1.32.03.5-1.21.5-0.50.5-0.91.91.61.51.31.51.31.61.51.71.51.51.61.5
Locomotor testing distance2.34.25.8-1.11.7-1.41.4-1.72.42.22.02.12.12.12.32.32.12.32.32.42.2
Locomotor testing rearing0.91.93.5-1.21.5-0.70.8-1.01.91.71.31.21.51.21.61.41.41.51.51.51.5
Locomotion in novel chamber2.43.14.7-0.10.9-2.12.1-1.51.61.71.42.21.61.81.92.11.41.52.12.12.0
Locomotion in novel chamber post-restriction0.30.52.51.6-1.0-1.10.8-1.1-0.5-0.2-0.60.6-0.50.4-0.10.3-0.40.40.20.1-0.0
Fecal boli incidents, locomotor time 10.10.20.40.0-0.40.5-0.50.4-0.5-0.3-0.6-0.5-0.2-0.6-0.5-0.5-0.2-0.4-0.5-0.5-0.5
Change in fecal boli incidents, locomotor task0.10.10.90.6-0.20.4-0.4-0.3-0.0-0.2-0.20.1-0.70.10.00.1-1.00.10.10.0-0.1
Time >=10cm from walls, locomotor time 10.30.31.61.3-1.0-0.50.5-0.5-0.8-0.6-0.50.3-0.10.1-0.4-0.00.0-0.0-0.1-0.2-0.2
Bouts of movement, locomotor time 11.82.15.0-1.80.52.2-2.22.1-0.5-0.2-0.5-1.9-0.5-1.8-1.1-1.6-0.6-1.3-1.5-1.4-1.1
Total resting periods, locomotor time 11.51.64.4-1.60.52.1-2.12.0-0.3-0.1-0.3-1.8-0.4-1.4-0.9-1.4-0.5-1.1-1.3-1.2-0.9
Rest time, locomotor task time 10.10.20.5-0.70.70.2-0.20.40.60.70.70.00.30.30.40.2-0.00.20.30.30.4
Distance moved, locomotor task time 10.10.10.60.10.0-0.50.5-0.4-0.1-0.00.10.20.40.10.10.10.8-0.00.10.10.1
Vertical activity count, locomotor time 10.51.33.51.0-0.2-1.91.9-1.90.50.30.41.50.11.01.01.30.20.71.31.20.9
Time >=10cm from walls, locomotor time 20.20.31.0-1.00.60.7-0.70.80.10.30.3-0.50.6-0.3-0.0-0.30.70.1-0.3-0.2-0.1
Bouts of movement, locomotor time 20.20.30.90.9-0.90.2-0.2-0.3-0.6-0.5-0.8-0.0-0.6-0.3-0.5-0.3-0.5-0.3-0.3-0.4-0.6
Total resting periods, locomotor time 20.10.20.40.5-0.70.4-0.4-0.1-0.4-0.4-0.7-0.2-0.5-0.3-0.4-0.3-0.4-0.3-0.3-0.4-0.5
Rest time, locomotor task time 20.40.51.00.10.2-1.01.0-0.90.60.40.40.90.70.70.70.80.70.50.80.80.8
Distance moved, locomotor task time 20.81.02.1-0.6-0.11.2-1.21.3-0.9-0.6-0.3-1.3-0.7-1.5-0.9-1.2-0.8-1.2-1.1-1.1-1.0
Vertical activity count, locomotor time 20.10.10.8-0.90.30.2-0.20.4-0.00.00.3-0.3-0.1-0.60.0-0.2-0.1-0.2-0.1-0.1-0.1
Light reinforcement 10.30.72.01.4-1.4-0.00.0-0.3-1.0-1.1-0.8-0.2-1.0-0.4-0.9-0.5-0.9-0.5-0.6-0.7-1.0
Light reinforcement 20.30.52.31.5-1.4-0.70.7-0.7-0.6-0.9-0.70.3-0.70.0-0.5-0.1-0.5-0.3-0.2-0.3-0.7
Bone: marrow area0.71.57.2-2.71.71.8-1.81.61.31.00.9-1.10.8-0.80.2-0.50.7-0.2-0.3-0.10.1
Bone: maximum diameter2.13.819.1-4.42.72.8-2.82.72.31.51.5-1.61.4-1.40.4-0.71.5-0.7-0.5-0.10.1
Bone: maximum force0.40.84.2-2.11.20.7-0.70.61.80.91.0-0.20.7-0.20.50.20.70.10.20.40.3
Bone: maximum moment0.50.95.3-2.31.41.0-1.00.91.81.01.1-0.40.7-0.30.60.10.6-0.10.20.30.4
Mean time between licks in bursts0.51.21.9-0.3-0.31.3-1.31.1-0.7-0.8-1.1-1.3-1.3-1.4-1.0-1.2-1.4-1.3-1.1-1.1-1.0
Mean num. licks in bursts1.82.83.8-0.31.3-1.51.5-1.51.31.82.01.81.61.81.91.91.51.81.91.91.9
Cd content in liver2.83.15.70.80.3-2.42.4-2.41.41.11.22.30.92.31.72.10.42.12.12.01.7
Co content in liver1.21.43.11.4-0.2-1.71.7-1.80.00.50.51.50.61.60.91.30.51.61.21.11.0
Cu content in liver0.10.10.30.2-0.1-0.50.5-0.60.20.00.10.50.30.50.30.40.40.50.40.40.3
Fe content in liver0.80.92.8-0.90.51.4-1.41.7-0.4-0.1-0.3-1.3-0.2-1.3-0.6-1.0-0.3-1.3-0.9-0.9-0.5
K content in liver0.20.21.00.8-0.7-0.30.3-0.1-1.0-0.5-0.5-0.1-0.2-0.2-0.5-0.30.2-0.3-0.4-0.4-0.3
Mg content in liver0.20.20.40.2-0.50.0-0.00.3-0.6-0.6-0.6-0.5-0.3-0.6-0.6-0.60.1-0.6-0.6-0.6-0.5
Mn content in liver0.10.10.20.4-0.3-0.40.4-0.4-0.1-0.2-0.10.3-0.10.20.10.20.00.20.20.10.0
Na content in liver1.31.32.71.1-1.60.1-0.10.3-1.2-1.5-1.7-0.8-1.4-1.0-1.3-1.1-1.2-1.3-1.1-1.2-1.3
Rb content in liver1.82.13.81.3-1.50.8-0.80.8-2.0-1.7-1.7-1.2-1.6-1.4-1.6-1.4-1.4-1.6-1.5-1.6-1.5
Se content in liver0.70.82.31.3-1.5-0.40.4-0.3-1.2-1.2-1.3-0.2-1.2-0.6-1.0-0.6-0.6-0.8-0.7-0.7-0.9
Sr content in liver1.11.02.91.5-1.0-1.71.7-1.7-0.4-0.4-0.51.1-0.41.00.20.8-0.20.90.70.50.2
Zn content in liver0.50.61.61.0-0.4-1.31.3-1.2-0.20.00.00.90.21.00.40.70.40.90.60.50.5
Bone: minimum diameter1.32.312.0-3.52.32.1-2.12.11.81.41.1-1.20.9-1.20.4-0.40.6-0.7-0.3-0.00.2
Time in familiar zone, hab. session 11.01.02.41.0-0.2-1.41.4-1.50.40.20.31.40.41.20.81.20.21.01.11.00.8
Time in novel zone, hab. session 11.41.43.4-1.40.21.8-1.81.8-0.2-0.4-0.4-1.6-0.5-1.6-1.0-1.4-0.2-1.4-1.3-1.2-1.0
Total zone transitions, hab. session 10.91.22.9-1.71.6-0.20.20.11.51.51.60.51.10.51.30.91.20.51.01.11.3
Total locomotion distance, hab. session 10.10.10.7-0.50.10.2-0.20.6-0.0-0.20.0-0.4-0.2-0.7-0.2-0.40.0-0.8-0.3-0.3-0.1
Locomotion velocity, hab. session 10.10.10.7-0.30.10.2-0.20.5-0.2-0.20.0-0.4-0.3-0.6-0.2-0.3-0.1-0.8-0.3-0.3-0.1
Time in familiar zone, hab. session 22.02.16.5-1.81.02.6-2.62.50.00.10.1-1.9-0.2-1.7-0.7-1.4-0.5-1.5-1.3-1.1-0.8
Time in novel zone, hab. session 21.61.64.21.0-0.4-2.02.0-2.00.50.30.31.70.41.51.01.40.41.41.31.21.0
Total zone transitions, hab. session 21.01.33.9-1.92.00.2-0.20.31.51.61.50.31.10.31.30.80.70.40.91.01.3
Total locomotion distance, hab. session 20.50.62.3-1.51.40.3-0.30.41.01.01.10.00.80.00.80.40.60.00.50.60.9
Locomotion velocity, hab. session 20.30.41.3-1.21.10.1-0.10.20.90.80.90.10.70.10.70.40.60.10.50.50.8
Novel to familiar place preference ratio0.30.30.5-0.0-0.30.4-0.40.6-0.4-0.5-0.5-0.7-0.5-0.6-0.6-0.7-0.4-0.5-0.7-0.6-0.6
Novelty place preference0.30.30.6-0.2-0.20.5-0.50.7-0.3-0.4-0.4-0.7-0.4-0.6-0.6-0.7-0.2-0.6-0.7-0.6-0.6
Time in novel zone, NPP test0.60.71.6-0.70.01.1-1.11.3-0.2-0.4-0.4-1.1-0.5-1.0-0.7-1.0-0.3-0.9-0.9-0.9-0.8
Total zone transitions, NPP test0.70.94.5-2.11.70.9-0.91.01.21.21.2-0.40.9-0.20.70.10.70.00.30.40.8
Total locomotion distance, NPP test0.40.62.9-1.71.30.9-0.91.10.80.60.7-0.60.4-0.50.4-0.20.3-0.5-0.10.00.4
Locomotion velocity, NPP test0.20.31.3-1.11.10.1-0.10.30.80.70.7-0.00.50.10.60.20.50.10.30.40.7
Intraocular pressure1.31.87.3-2.71.82.1-2.12.20.91.00.9-1.50.2-1.10.0-0.8-0.4-0.8-0.6-0.4-0.0
Delta distance traveled before/after self-admin0.50.51.8-1.31.10.5-0.50.60.60.80.8-0.11.00.10.40.11.30.40.10.30.4
Delta ambulatory time before/after self-admin0.60.72.3-1.50.91.3-1.31.40.00.30.2-1.00.5-0.7-0.3-0.70.9-0.3-0.7-0.5-0.3
Parametrial fat weight3.37.840.9-6.44.14.2-4.24.02.32.01.8-2.71.4-2.10.4-1.30.8-0.9-0.9-0.50.1
Pavlov. Cond. lever latency0.10.20.6-0.70.60.7-0.70.80.00.20.1-0.40.2-0.40.0-0.20.3-0.2-0.2-0.10.0
Pavlov. Cond. magazine entry latency0.10.20.7-0.70.70.4-0.40.40.20.70.8-0.20.5-0.00.3-0.00.30.10.10.10.3
Pavlov. Cond. change in total contacts0.30.30.4-0.00.3-0.70.7-0.70.40.50.70.70.50.70.60.60.50.60.60.60.6
Pavlov. Cond. index score0.30.41.0-0.50.6-0.30.2-0.30.50.91.00.40.80.60.60.50.60.60.60.60.7
Pavlov. Cond. latency score0.20.30.8-0.30.5-0.30.3-0.40.50.80.90.50.70.50.60.50.50.60.50.50.6
Pavlov. Cond. lever contacts0.10.20.60.8-0.8-0.60.5-0.5-0.3-0.4-0.30.2-0.40.2-0.3-0.0-0.60.0-0.0-0.1-0.3
Pavlov. Cond. magazine entry number0.91.22.91.3-1.50.1-0.00.1-1.1-1.6-1.7-0.5-1.3-0.8-1.2-0.8-1.0-1.0-0.9-1.0-1.2
Pavlov. Cond. intertrial magazine entries0.10.10.3-0.50.40.3-0.30.20.40.10.1-0.1-0.1-0.20.20.0-0.3-0.20.10.10.1
Pavlov. Cond. lever-magazine prob. diff.0.20.20.7-0.30.5-0.20.2-0.20.30.70.90.30.60.50.40.40.50.50.40.40.5
Pavlov. Cond. response bias0.10.10.4-0.10.2-0.40.4-0.40.20.50.60.40.30.50.40.40.10.50.40.40.4
Pavlov. Cond. lever latency3.04.16.80.60.9-2.02.0-2.51.11.71.92.51.82.52.12.41.82.62.32.32.1
Pavlov. Cond. magazine entry latency0.80.93.4-1.80.91.5-1.51.70.40.20.2-1.20.2-1.0-0.3-0.80.4-0.8-0.7-0.6-0.3
Pavlov. Cond. change in total contacts2.54.07.8-1.1-0.42.3-2.32.7-0.9-1.3-1.5-2.5-1.7-2.7-1.8-2.3-1.8-2.8-2.2-2.1-1.8
Pavlov. Cond. index score2.12.86.6-1.60.02.1-2.12.6-0.3-0.9-1.0-2.2-1.1-2.2-1.5-2.0-0.9-2.2-1.8-1.7-1.4
Pavlov. Cond. latency score2.02.66.4-1.70.22.1-2.12.5-0.2-0.7-0.8-2.2-0.9-2.1-1.4-1.9-0.7-2.0-1.8-1.6-1.3
Pavlov. Cond. lever contacts1.82.54.5-0.8-0.61.6-1.62.0-0.6-1.3-1.5-2.0-1.5-2.1-1.6-1.9-1.4-2.1-1.8-1.7-1.6
Pavlov. Cond. magazine entry number0.81.03.01.7-0.7-1.61.6-1.7-0.3-0.1-0.01.40.11.20.51.00.01.00.90.80.5
Pavlov. Cond. intertrial magazine entries0.00.10.2-0.20.10.0-0.0-0.30.50.30.30.30.30.20.20.30.30.30.30.30.0
Pavlov. Cond. lever-magazine prob. diff.1.72.25.6-1.60.11.8-1.82.4-0.1-0.7-0.8-2.0-0.9-2.0-1.3-1.7-0.7-1.9-1.6-1.5-1.2
Pavlov. Cond. response bias2.12.85.4-1.2-0.21.9-1.92.3-0.5-1.1-1.3-2.2-1.4-2.2-1.6-2.0-1.3-2.2-1.9-1.8-1.5
LgA PC1 addiction-like behavior0.20.40.8-0.60.6-0.60.6-0.50.90.60.70.50.60.50.70.60.60.50.70.70.8
Time in closed arm before self-admin0.10.10.30.3-0.2-0.30.3-0.5-0.0-0.5-0.40.2-0.5-0.10.10.2-0.6-0.30.20.20.1
Time in closed arm after self-admin0.30.30.80.8-0.3-0.90.9-0.70.2-0.00.20.8-0.30.60.40.6-0.70.20.60.50.5
Time in open arm before self-admin0.30.31.91.4-1.1-0.50.5-0.3-0.7-0.4-0.30.1-0.10.2-0.6-0.20.20.1-0.4-0.4-0.5
Time in open arm after self-admin1.21.32.2-0.2-0.51.4-1.41.3-1.1-0.9-1.0-1.5-0.4-1.3-1.3-1.40.1-0.9-1.5-1.4-1.3
Bone: periosteal estimation1.73.719.1-4.43.02.4-2.42.22.51.91.8-1.21.6-1.00.8-0.21.4-0.3-0.00.30.6
Bone: periosteal perimeter2.54.323.1-4.83.22.4-2.42.32.92.01.9-1.11.9-0.91.0-0.11.9-0.20.10.50.7
Bone: post-yield work1.11.62.4-0.2-0.71.5-1.51.4-0.8-1.3-1.2-1.6-1.2-1.2-1.4-1.5-1.2-1.1-1.5-1.5-1.5
Progressive ratio test 1 active lever presses1.21.42.9-1.30.41.6-1.51.7-0.5-0.5-0.5-1.7-0.8-1.7-0.9-1.4-1.0-1.5-1.2-1.2-0.9
Progressive ratio test 1 breakpoint1.21.52.9-1.20.31.6-1.51.6-0.6-0.5-0.5-1.7-0.9-1.7-0.9-1.4-1.1-1.5-1.3-1.2-0.9
Progressive ratio test 1 inactive lever presses1.62.34.9-1.10.02.2-2.21.8-0.9-0.8-0.9-2.1-1.0-1.8-1.4-1.8-1.1-1.2-1.8-1.7-1.5
Progressive ratio test 2 active lever presses0.91.03.7-1.91.01.8-1.81.20.00.30.2-1.3-0.2-1.2-0.3-0.9-0.2-0.3-0.8-0.7-0.5
Progressive ratio test 2 breakpoint0.91.03.9-2.01.11.8-1.81.20.10.40.2-1.3-0.1-1.1-0.3-0.9-0.1-0.2-0.7-0.6-0.4
Progressive ratio test 2 inactive lever presses0.81.33.6-1.60.61.9-1.91.5-0.3-0.2-0.3-1.6-0.4-1.4-0.8-1.3-0.3-0.7-1.2-1.1-0.9
ShA PR total presses1.11.31.80.9-1.10.6-0.60.7-1.2-1.2-1.2-1.0-1.3-1.1-1.3-1.2-1.3-1.3-1.2-1.3-1.2
Incentive Sensitization - Responses0.40.62.3-1.50.91.4-1.50.60.10.40.3-0.90.1-0.6-0.2-0.60.40.5-0.5-0.4-0.3
Incentive Sensitization - Breakpoint0.40.52.0-1.40.81.4-1.40.50.10.40.3-0.90.2-0.5-0.2-0.60.40.5-0.5-0.4-0.3
LgA PR total presses0.20.20.80.9-0.6-0.60.6-0.7-0.2-0.3-0.20.40.00.4-0.00.20.20.60.20.1-0.0
Sum of active levers in priming session hrs 5-60.60.61.01.0-1.00.4-0.40.2-1.0-0.8-0.9-0.6-0.6-0.5-1.0-0.8-0.2-0.4-0.9-0.9-1.0
Progressive ratio0.60.91.51.0-1.2-0.20.00.7-1.0-1.2-1.1-0.7-1.1-0.8-1.1-0.9-0.9-1.2-0.9-1.0-0.9
Food seeking constrained by brief footshock2.32.83.60.4-1.21.6-1.61.5-1.6-1.6-1.6-1.8-1.6-1.8-1.8-1.9-1.8-1.9-1.9-1.9-1.8
Seeking ratio, punishment vs. effort0.10.20.9-0.80.60.9-0.80.00.40.50.4-0.20.3-0.00.20.00.00.30.10.10.0
Retroperitoneal fat weight3.414.680.2-9.06.25.1-5.14.93.83.63.2-3.02.8-2.11.3-1.12.1-0.4-0.60.01.0
Reaction time number correct0.30.62.7-1.61.11.3-1.31.00.20.40.3-0.90.5-0.6-0.1-0.60.50.1-0.5-0.3-0.1
Reaction time mean minus median0.00.10.6-0.80.40.3-0.40.50.50.30.2-0.10.4-0.10.1-0.00.5-0.1-0.00.00.0
Reaction time mean minus median AUC0.30.71.4-0.90.9-0.20.1-0.41.21.00.90.61.10.70.90.81.10.90.80.90.8
Reaction time num false alarms0.10.10.4-0.2-0.10.4-0.40.6-0.2-0.00.0-0.5-0.3-0.4-0.3-0.4-0.6-0.3-0.4-0.4-0.3
Reaction time num false alarms AUC0.00.00.1-0.10.00.1-0.10.3-0.00.20.3-0.1-0.0-0.1-0.1-0.1-0.4-0.1-0.1-0.1-0.1
Reaction time trials correct on left0.30.62.7-1.61.11.3-1.31.00.20.40.3-0.90.5-0.6-0.1-0.60.50.1-0.5-0.3-0.1
Reaction time trials on left0.30.62.9-1.71.11.4-1.41.00.30.40.3-0.90.5-0.6-0.0-0.50.50.1-0.5-0.3-0.1
Reaction time mean0.50.91.40.00.3-1.21.2-0.91.00.80.71.10.81.10.91.10.81.01.01.00.9
Reaction time mean AUC0.30.51.30.5-0.2-1.11.1-0.90.60.30.41.00.40.90.60.80.40.70.80.70.6
Median of all reaction times1.01.52.80.30.2-1.61.7-1.41.10.90.91.50.91.51.11.40.91.41.31.31.2
Reaction time omissions0.10.10.5-0.70.20.4-0.40.60.40.20.0-0.4-0.2-0.4-0.1-0.2-0.4-0.5-0.2-0.2-0.2
Reaction time false alarm rate0.10.20.80.7-0.7-0.30.30.1-0.4-0.3-0.10.0-0.6-0.1-0.3-0.1-0.9-0.5-0.1-0.2-0.3
Reaction time premature initiation rate1.72.44.3-0.61.3-1.11.1-1.11.31.71.61.62.01.61.71.72.11.61.71.71.8
Reaction time premature initiations1.62.96.3-1.62.0-0.40.4-0.61.62.11.91.22.41.51.81.52.51.81.61.71.9
Std. dev. reaction times0.30.52.0-1.41.00.2-0.20.51.20.90.80.20.80.20.70.40.90.20.50.60.6
Reaction time trials completed0.30.62.9-1.71.11.4-1.41.00.30.40.3-0.90.5-0.6-0.0-0.50.50.1-0.5-0.3-0.1
Reaction time trials AUC0.40.73.1-1.71.21.4-1.41.00.30.40.3-1.00.4-0.6-0.0-0.60.50.0-0.5-0.3-0.0
Run reversals in cocaine runway, females1.31.32.6-1.21.3-1.10.9-0.11.21.31.40.91.60.81.21.11.60.61.11.21.3
Run reversals in cocaine runway, males0.90.91.71.2-1.30.0-0.00.2-1.1-1.0-1.0-0.6-1.1-0.6-1.1-0.9-1.2-0.9-0.9-1.0-1.0
Latency to leave start box in cocaine runway0.20.31.51.2-0.9-0.40.5-0.8-0.2-0.4-0.60.5-0.20.3-0.10.3-0.00.20.20.1-0.2
Latency to leave start box in cocaine runway, F0.40.52.01.4-0.9-0.80.9-1.3-0.1-0.3-0.50.9-0.20.70.10.6-0.00.50.50.40.1
Latency to leave start box in cocaine runway, M0.10.10.2-0.30.10.5-0.50.40.0-0.0-0.0-0.30.1-0.3-0.2-0.2-0.0-0.2-0.3-0.2-0.3
Std. dev. time between licks in bursts2.43.34.7-0.1-1.01.9-1.91.7-1.3-1.8-2.0-2.0-1.8-2.2-1.9-2.0-1.7-2.1-2.0-2.0-1.9
Total sessions with >9 infusions0.60.74.4-2.11.41.1-1.10.80.80.80.8-0.60.4-0.50.4-0.2-0.00.1-0.00.10.2
Short access day 1 total inactive lever presses0.60.82.3-1.40.71.5-1.51.2-0.3-0.1-0.1-1.20.3-0.9-0.5-0.90.6-0.5-0.9-0.7-0.7
Short access day 10 total inactive lever presses0.10.31.2-1.10.90.4-0.40.20.70.70.5-0.10.60.20.40.10.70.80.10.20.2
Short access day 1 total infusions0.10.20.9-1.00.50.6-0.50.30.10.10.1-0.60.3-0.5-0.1-0.40.2-0.1-0.3-0.3-0.1
Short access day 10 total infusions0.60.71.3-0.0-0.50.7-0.70.6-0.7-0.8-0.7-1.0-1.0-1.0-0.9-1.0-1.2-0.9-0.9-0.9-0.8
Short access total infusions0.40.51.0-0.90.31.0-1.00.8-0.2-0.3-0.2-1.0-0.4-0.9-0.5-0.8-0.6-0.5-0.8-0.7-0.5
ShA early post infusion interval0.60.61.00.8-0.90.3-0.30.4-1.0-1.0-1.0-0.5-0.9-0.6-0.8-0.7-0.9-0.6-0.7-0.8-0.9
ShA late post infusion interval0.10.10.5-0.30.30.0-0.0-0.00.30.50.30.10.50.20.20.20.70.50.10.20.1
ShA early loading1.81.83.20.1-0.61.4-1.41.7-1.0-1.0-0.9-1.6-1.3-1.5-1.3-1.5-1.6-1.8-1.5-1.5-1.2
ShA late loading0.50.71.31.1-1.20.0-0.00.3-1.1-1.1-1.0-0.5-0.9-0.5-0.9-0.7-0.9-0.8-0.8-0.8-0.9
Short access day 1 locomotion0.40.51.2-0.90.20.9-0.90.9-0.3-0.3-0.2-1.1-0.2-1.0-0.6-0.9-0.2-0.6-0.9-0.8-0.7
Short access day 10 total locomotion1.52.83.8-1.11.6-1.41.3-1.11.91.91.91.62.01.51.91.81.81.61.81.91.9
Short access total locomotion0.81.02.1-1.11.2-0.50.5-0.31.21.41.50.71.10.71.10.90.70.81.01.11.1
ShA early average infusions3.74.36.11.2-1.71.8-1.81.8-2.3-2.0-2.0-2.2-1.9-2.2-2.4-2.4-1.7-2.3-2.4-2.5-2.3
ShA late average infusions1.21.22.31.2-1.30.4-0.40.5-1.3-1.3-1.2-0.8-1.4-0.9-1.2-1.0-1.5-1.2-1.0-1.1-1.1
ShA early timeout2.92.94.10.7-1.31.7-1.71.5-1.7-1.6-1.4-1.9-1.7-1.8-1.9-2.0-1.7-1.7-2.0-2.0-1.9
ShA late timeout0.20.20.60.8-0.6-0.20.2-0.0-0.6-0.6-0.6-0.1-0.5-0.2-0.4-0.2-0.3-0.4-0.3-0.3-0.3
ShA early titration2.22.43.70.3-0.91.6-1.61.6-1.5-1.4-1.3-1.9-1.1-1.7-1.8-1.9-0.9-1.7-1.9-1.9-1.7
ShA late titration0.10.10.40.3-0.40.1-0.10.3-0.3-0.4-0.4-0.2-0.5-0.3-0.3-0.3-0.6-0.5-0.3-0.3-0.3
ShA total infusions0.91.21.60.9-1.00.7-0.70.8-1.2-1.2-1.1-1.0-1.2-1.0-1.2-1.1-1.2-1.3-1.1-1.2-1.2
One hour access (0.3 mA shock)4.85.510.5-1.4-0.33.2-3.22.7-1.7-1.6-1.6-3.2-1.4-2.9-2.3-2.9-0.9-2.3-2.8-2.7-2.4
Shock compulsivity1.01.84.0-1.92.00.0-0.0-0.51.72.01.90.71.40.91.51.11.21.41.21.31.4
Compulsive drug intake1.72.03.0-0.3-0.61.7-1.71.7-1.2-1.2-1.4-1.7-0.7-1.6-1.5-1.7-0.3-1.6-1.7-1.6-1.6
One hour access (shock baseline)0.10.20.9-1.00.50.8-0.70.40.00.20.2-0.7-0.1-0.5-0.2-0.5-0.0-0.2-0.4-0.3-0.2
Social response proportion3.54.05.5-1.92.3-1.01.0-1.12.32.42.31.62.21.92.32.02.22.42.02.12.2
Social responses1.31.78.9-3.02.01.9-1.91.71.11.10.9-1.10.9-0.70.3-0.50.9-0.0-0.3-0.10.2
Social time1.01.42.6-1.51.6-0.10.1-0.21.31.51.50.61.60.81.20.91.51.21.01.11.2
Soleus weight3.410.119.0-3.94.4-0.10.1-0.33.94.14.11.84.12.23.52.64.22.92.83.03.4
Bone: stiffness0.10.11.5-0.90.10.2-0.2-0.01.20.10.20.0-0.0-0.20.20.10.1-0.00.10.2-0.1
Tibialis anterior weight0.31.01.50.4-0.51.0-1.11.1-1.1-0.8-0.8-1.2-0.9-1.1-1.0-1.2-0.9-1.2-1.1-1.1-0.9
Time to tail flick, vehicle, before self-admin0.30.31.1-0.80.7-0.00.10.10.70.50.50.30.80.40.50.41.10.40.40.50.5
Time to tail flick, vehicle, after self-admin0.10.10.60.5-0.50.1-0.20.0-0.3-0.3-0.30.00.20.0-0.3-0.10.8-0.0-0.2-0.2-0.3
Time to tail flick, test, before self-admin1.71.72.4-0.20.8-1.21.3-1.41.21.31.41.51.11.51.41.51.01.61.51.51.4
Time to tail flick, test, after self-admin0.50.51.6-0.90.21.0-1.01.2-0.1-0.5-0.5-0.9-0.2-0.8-0.5-0.80.1-0.8-0.8-0.7-0.6
Delta time to tail flick, vehicle, before/after SA0.90.91.20.3-0.70.9-1.00.7-0.9-1.0-1.1-1.0-0.8-1.1-1.1-1.1-0.5-1.1-1.1-1.1-1.1
Delta time to tail flick, test, before/after SA0.50.51.3-0.4-0.10.8-0.81.1-0.4-0.6-0.6-0.9-0.4-0.8-0.6-0.8-0.2-0.9-0.8-0.7-0.6
Tibia length1.33.68.3-2.52.4-0.60.7-0.42.92.42.31.22.31.32.11.72.21.51.81.92.0
Ambulatory time before self-admin3.14.66.5-0.11.1-2.42.4-2.51.91.81.92.61.72.42.32.51.42.42.52.52.4
Ambulatory time after self-admin3.64.28.6-0.91.5-1.81.8-1.81.81.92.02.12.52.12.12.22.92.52.12.22.1
Bone: tissue strength0.30.31.40.6-0.60.3-0.30.2-0.7-0.3-0.5-0.4-0.8-0.5-0.6-0.5-1.2-0.7-0.5-0.5-0.6
Total heroin consumption0.91.04.7-2.21.31.6-1.71.40.40.40.3-1.2-0.1-1.0-0.1-0.7-0.4-0.6-0.6-0.4-0.3
Total infusions0.20.30.6-0.70.30.8-0.80.70.1-0.20.0-0.6-0.5-0.6-0.3-0.5-0.6-0.5-0.4-0.4-0.2
Bone: trabecular number0.50.82.2-1.10.31.2-1.21.5-0.1-0.2-0.3-1.2-0.4-1.3-0.6-1.0-0.1-1.2-0.9-0.8-0.7
Bone: trabecular spacing0.10.20.60.8-0.6-0.00.0-0.1-0.6-0.5-0.4-0.2-0.5-0.1-0.4-0.3-0.8-0.3-0.3-0.4-0.4
Bone: trabecular thickness1.92.410.9-3.32.22.1-2.12.31.31.21.2-1.21.4-1.10.3-0.51.7-0.7-0.4-0.10.2
Bone: trabecular tissue density0.30.41.00.2-0.2-1.01.0-1.00.80.00.10.80.40.70.50.70.50.70.60.60.4
Water consumed over 24 hours0.91.21.8-1.01.1-0.70.7-0.81.41.21.01.01.00.91.31.21.21.11.21.31.2
Number of responses in last shaping day0.10.21.0-0.20.20.3-0.30.4-0.20.10.1-0.4-0.3-0.5-0.1-0.3-1.0-0.8-0.2-0.2-0.1