Hub : Genes

LOC102550304

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 NAcc gene expression LOC102550304 0.18 0.08 0.0e+00 0.24 0.23 0.24 0.25 5.9e-28 6.0e-27 4.0e-28 7.8e-29
2 Brain gene expression LOC102550304 0.38 0.12 0.0e+00 0.49 0.46 0.5 0.5 1.9e-51 2.9e-47 1.1e-52 3.9e-53
3 Liver intron excision ratio chr3_131523495_131523877 0.04 0.03 5.7e-04 0.02 0.02 0.02 0.02 4.2e-03 4.3e-03 4.8e-03 3.8e-03
4 BLA gene expression LOC102550304 0.41 0.14 0.0e+00 0.33 0.26 0.33 0.34 1.5e-18 4.6e-14 3.1e-18 1.4e-18
5 LHb gene expression LOC102550304 0.35 0.16 2.6e-06 0.25 0.22 0.23 0.15 9.9e-07 7.5e-06 2.8e-06 2.2e-04
6 pVTA gene expression LOC102550304 0.35 0.12 0.0e+00 0.36 0.27 0.37 0.38 1.2e-16 2.8e-12 6.8e-17 2.4e-17
7 PL gene expression LOC102550304 0.45 0.12 0.0e+00 0.5 0.4 0.5 0.51 8.7e-64 1.9e-47 1.3e-63 3.1e-64
8 Liver intron excision ratio chr3_131523495_131524054 0.04 0.03 5.9e-04 0.02 0.02 0.02 0.02 3.7e-03 4.3e-03 3.6e-03 3.6e-03
9 Liver gene expression LOC102550304 0.51 0.14 0.0e+00 0.38 0.37 0.38 0.38 1.9e-44 2.7e-43 2.5e-44 9.7e-44
10 OFC gene expression LOC102550304 0.44 0.17 4.1e-08 0.34 0.34 0.35 0.36 7.6e-09 8.6e-09 2.9e-09 1.9e-09
11 IL gene expression LOC102550304 0.43 0.15 6.5e-09 0.28 0.32 0.3 0.32 1.9e-07 2.1e-08 5.1e-08 2.5e-08
12 Adipose gene expression LOC102550304 0.71 0.13 0.0e+00 0.41 0.44 0.44 0.43 7.2e-49 6.6e-53 2.9e-54 6.6e-52

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12
Bone: apparent density0.00.10.2-0.3-0.2-0.3-0.20.1-0.2-0.3-0.50.2-0.2-0.10.3
Area under the delay curve0.60.62.3-0.90.4-0.80.40.80.30.3-1.50.40.61.1-0.8
BMI with tail7.123.128.85.35.45.05.3-5.05.25.34.4-4.94.03.5-3.6
BMI without tail5.110.616.64.13.43.73.4-4.03.43.43.2-3.12.41.8-2.1
Body weight7.932.946.76.86.46.36.4-6.36.26.25.6-5.64.33.3-3.9
Weight adjusted by age0.10.10.30.30.50.20.40.10.2-0.10.10.3-0.3-0.60.4
Bone surface0.10.20.60.60.30.60.3-0.70.40.40.8-0.60.10.0-0.0
Bone volume0.00.10.20.3-0.00.3-0.0-0.3-0.0-0.00.3-0.0-0.4-0.40.4
Breakpoint value in progressive ratio session0.20.20.50.70.40.60.4-0.70.50.50.7-0.50.20.0-0.2
Number of licking bursts0.20.20.50.20.40.40.4-0.40.50.4-0.0-0.30.60.7-0.6
Context. condit. distance diff. score0.00.00.10.30.10.20.10.10.00.00.2-0.1-0.0-0.20.1
Locomotion velocity, session 11.51.62.2-1.2-1.4-1.3-1.40.9-1.4-1.4-1.11.5-1.1-1.51.0
Locomotion distance, session 13.74.76.2-2.4-2.5-2.5-2.42.3-2.3-2.3-2.02.3-1.7-1.71.4
Locomotion velocity, session 21.41.63.5-1.9-1.2-1.9-1.11.4-1.2-1.3-1.61.3-0.5-0.50.4
Locomotion distance, session 25.17.28.8-2.6-3.0-2.7-2.82.4-2.8-2.9-2.22.9-2.6-2.72.4
Locomotion velocity, session 32.73.24.6-2.1-2.1-2.0-2.11.6-2.1-1.9-1.91.7-1.3-1.11.1
Locomotion distance, session 30.91.01.9-1.4-1.2-1.2-1.10.7-1.2-1.1-1.20.8-0.4-0.30.5
Stereotopy head waving bouts, day 30.00.00.20.3-0.10.0-0.00.1-0.1-0.10.10.0-0.3-0.50.3
Stereotopy head waving duration, day 30.00.10.20.50.10.30.2-0.10.10.10.4-0.2-0.1-0.20.0
Locomotion velocity, session 71.11.21.8-1.0-1.2-1.1-1.21.1-1.2-1.2-0.71.1-1.1-1.41.0
Locomotion distance, session 70.30.41.7-0.1-0.6-0.4-0.60.6-0.7-0.60.20.5-0.8-1.30.7
Stereotopy head waving bouts, day 70.10.10.20.40.30.40.3-0.30.20.30.3-0.30.30.2-0.2
Stereotopy head waving duration, day 70.10.10.3-0.5-0.3-0.3-0.30.3-0.3-0.3-0.50.20.00.20.0
Locomotion velocity, session 81.41.72.7-1.0-1.4-1.3-1.31.3-1.3-1.3-1.01.3-1.3-1.61.1
Locomotion distance, session 82.63.84.7-1.8-2.1-1.9-2.02.1-2.0-2.1-1.42.0-2.0-2.21.8
Degree of sensitization distance0.40.41.31.10.60.70.6-0.30.50.51.1-0.2-0.2-0.80.2
Degree of sensitization stereotypy0.50.50.70.60.70.70.7-0.80.70.70.5-0.70.80.8-0.7
Conditioned locomotion0.60.71.7-0.4-0.8-0.5-0.80.3-0.8-0.8-0.60.9-1.2-1.21.3
Cocaine response after cond. corrected1.71.92.6-1.1-1.5-1.2-1.51.3-1.5-1.5-0.81.5-1.5-1.61.3
Cocaine response after cond. not corrected2.73.03.5-1.5-1.8-1.6-1.91.8-1.9-1.9-1.31.8-1.8-1.91.6
Cocaine response before conditioning0.10.10.4-0.5-0.3-0.4-0.20.5-0.2-0.4-0.60.2-0.2-0.10.2
Saline control response0.50.72.21.50.40.80.4-0.30.30.31.10.0-0.8-1.50.8
Bone: connectivity density0.20.30.6-0.8-0.5-0.7-0.50.5-0.5-0.5-0.60.4-0.5-0.20.6
Bone: cortical apparent density0.10.20.6-0.60.1-0.50.20.40.20.0-0.6-0.30.40.8-0.5
Bone: cortical area0.30.51.20.51.10.41.0-0.31.00.90.3-0.50.70.6-0.8
Bone: cortical porosity0.40.40.70.60.80.60.8-0.70.80.70.4-0.50.50.5-0.5
Bone: cortical porosity0.70.71.10.81.00.81.0-0.81.11.00.7-0.70.70.7-0.7
Bone: cortical thickness0.61.02.00.01.30.11.3-0.11.21.0-0.3-0.81.31.4-1.4
Bone: cortical thickness0.60.72.0-1.4-0.3-1.2-0.31.1-0.4-0.5-1.40.8-0.30.20.2
Bone: cortical tissue density0.10.10.4-0.50.1-0.40.20.40.10.0-0.5-0.30.30.7-0.4
Condit. Reinf. active minus inactive responses0.00.00.1-0.0-0.10.2-0.1-0.4-0.2-0.1-0.20.30.00.1-0.1
Condit. Reinf. active-inactive response ratio0.00.10.2-0.2-0.10.1-0.1-0.3-0.2-0.2-0.40.5-0.10.00.2
Condit. Reinf. active responses0.00.00.1-0.2-0.2-0.1-0.2-0.1-0.3-0.3-0.40.30.1-0.0-0.1
Condit. Reinf. inactive responses0.00.00.10.0-0.0-0.1-0.10.3-0.1-0.10.1-0.1-0.0-0.3-0.1
Incentive salience index mean0.20.20.7-0.7-0.3-0.5-0.20.0-0.3-0.3-0.80.40.30.5-0.3
Condit. Reinf. lever presses0.40.52.2-0.60.4-0.20.5-0.20.30.3-0.5-0.31.21.5-1.2
Condit. Reinf. active minus inactive responses0.70.82.11.40.81.20.8-1.10.80.81.4-1.00.3-0.3-0.3
Condit. Reinf. active-inactive response ratio1.01.02.01.40.91.30.8-1.30.90.91.4-1.10.60.2-0.5
Condit. Reinf. active responses0.60.81.31.00.90.90.9-0.90.90.90.9-1.10.80.6-0.7
Condit. Reinf. inactive responses0.20.31.0-0.10.5-0.00.5-0.20.50.5-0.2-0.60.71.0-0.7
Condit. Reinf. lever presses2.63.65.42.31.82.21.8-2.31.81.92.1-2.11.40.9-1.3
Condit. Reinf. lever reinforcers received0.71.01.71.21.01.11.0-1.01.01.11.1-1.30.90.6-0.8
Conditioned reinforcement - actives1.81.83.7-0.7-1.8-0.9-1.40.9-1.2-1.2-0.71.4-1.9-1.91.4
Conditioned reinforcement - inactives3.03.46.3-0.9-2.1-1.2-2.01.6-1.8-1.9-0.71.7-2.5-2.52.2
Conditioned locomotion0.60.81.9-1.0-1.4-0.8-1.40.8-0.8-0.7-0.90.8-0.7-0.40.2
Patch foraging indifference point 0 sec1.01.74.8-0.1-1.4-0.3-1.40.6-1.3-1.40.40.9-1.8-2.21.7
Patch foraging indifference point AUC0.50.51.2-1.0-0.7-0.9-0.90.7-0.6-0.6-1.10.8-0.2-0.10.1
Delay disc. indifference point, 0s delay1.01.12.10.41.30.61.4-0.51.21.20.0-0.91.31.4-1.5
Delay disc. indifference point, 16s delay1.01.03.4-1.5-0.7-1.4-0.81.2-0.7-0.7-1.91.1-0.30.20.1
Delay disc. indifference point, 2s delay1.61.83.30.61.50.71.6-0.91.61.60.2-1.01.61.8-1.8
Delay disc. indifference point, 24s delay2.92.87.4-2.2-1.3-2.2-1.42.0-1.4-1.4-2.71.8-0.8-0.10.7
Delay disc. indifference point, 4s delay1.11.12.10.41.50.41.5-0.41.41.3-0.2-0.71.21.3-1.2
Delay disc. indifference point, 8s delay0.91.03.8-1.4-0.3-1.4-0.41.4-0.5-0.5-2.01.1-0.20.30.1
Indifference point function ln k0.30.41.3-0.0-0.6-0.2-0.40.2-0.6-0.50.00.5-1.0-1.11.1
Indifference point function log k0.30.41.3-0.0-0.6-0.2-0.40.2-0.6-0.50.00.5-1.0-1.11.1
Patch foraging total patch changes 0 sec1.21.94.7-0.3-1.6-0.5-1.50.7-1.4-1.60.11.1-1.9-2.21.8
Patch foraging total patch changes 12 sec0.20.20.80.50.40.50.3-0.40.60.50.9-0.40.30.0-0.5
Patch foraging total patch changes 18 sec1.51.92.7-1.0-1.5-1.0-1.61.4-1.5-1.6-0.71.4-1.5-1.61.3
Patch foraging total patch changes 24 sec0.10.10.4-0.1-0.4-0.2-0.60.2-0.5-0.40.10.3-0.4-0.50.2
Patch foraging total patch changes 6 sec0.30.40.9-0.3-0.8-0.0-1.00.1-0.7-0.80.20.5-0.7-0.90.7
Patch foraging time to switch 0 sec2.13.25.51.62.31.72.1-1.22.11.91.8-1.81.81.5-1.6
Patch foraging water rate 0 sec2.23.65.1-1.9-2.3-2.0-2.11.5-2.1-2.0-2.01.9-1.7-1.31.5
Patch foraging water rate 12 sec2.53.86.5-2.5-2.2-2.4-2.02.2-2.0-1.9-2.31.8-1.3-0.71.0
Patch foraging water rate 18 sec8.611.615.2-3.5-3.4-3.9-3.23.7-3.5-3.5-3.53.5-3.1-2.83.1
Patch foraging water rate 24 sec3.85.36.0-2.1-2.4-2.2-2.42.1-2.5-2.4-2.12.4-2.3-2.22.4
Patch foraging water rate 6 sec4.26.28.5-2.5-2.7-2.8-2.62.4-2.7-2.5-2.92.6-2.0-1.62.1
Seeking ratio, delayed vs. immediate footshock0.20.20.60.50.70.60.7-0.80.30.20.5-0.40.3-0.10.1
Distance traveled before self-admin0.20.30.40.40.50.40.5-0.60.60.60.6-0.60.40.5-0.1
Distance traveled after self-admin0.20.21.1-0.40.0-0.00.2-0.20.00.0-0.3-0.20.71.0-0.6
Extensor digitorum longus weight0.10.30.90.90.60.70.6-0.70.50.50.6-0.50.1-0.1-0.1
Bone: elastic displacement0.40.50.90.40.70.30.7-0.60.80.70.5-0.90.80.7-0.9
Bone: elastic work3.24.15.61.82.41.82.3-1.92.32.11.5-2.02.01.8-2.1
Bone: endosteal estimation1.22.56.82.61.42.21.4-2.01.41.52.2-1.20.4-0.1-0.2
Bone: endosteal perimeter0.20.51.41.20.20.90.0-0.70.10.31.10.1-0.6-1.00.7
Epididymis fat weight5.713.217.34.04.14.14.2-4.23.83.93.7-3.72.92.1-2.5
Delta time in closed arm before/after self-admin0.30.30.8-0.4-0.5-0.4-0.70.6-0.8-0.9-0.40.5-0.4-0.50.5
Delta time in open arm before/after self-admin1.51.52.81.40.91.61.0-1.71.21.31.6-1.30.70.8-0.6
Diff in mean of infusions in LGA sessions0.10.10.4-0.6-0.2-0.4-0.30.3-0.2-0.2-0.40.10.20.5-0.2
Delay discount exponential model param0.60.62.71.0-0.21.0-0.2-0.9-0.2-0.11.6-0.5-0.5-1.00.7
Extinction: sum of active levers before priming0.30.30.7-0.1-0.5-0.3-0.60.2-0.6-0.6-0.10.5-0.7-0.80.8
Active lever presses in extinction session 60.50.51.91.20.40.80.4-0.70.60.61.4-0.5-0.2-0.80.1
Bone: final force0.71.22.11.11.40.91.4-1.01.31.30.5-0.91.00.9-1.0
Bone: final moment0.61.01.61.01.30.91.2-0.91.21.20.6-0.80.80.8-0.8
Food consumed during 24 hour testing period0.20.30.50.60.70.20.7-0.40.70.70.2-0.30.60.2-0.6
Glucose0.30.41.51.20.70.80.6-0.70.50.50.7-0.40.0-0.50.1
Heart weight2.13.04.92.11.62.01.9-1.91.91.92.2-1.60.90.7-1.4
Delay discount hyperbolic model param0.50.61.80.7-0.50.7-0.5-0.6-0.5-0.41.3-0.2-0.7-1.10.9
Intermittent access intake day 1-15 change0.40.41.80.9-0.00.80.3-0.40.40.41.3-0.4-0.3-0.90.0
Intermittent access intake escalation0.20.20.90.6-0.10.40.3-0.10.20.20.9-0.1-0.5-1.00.2
Intermittent access intake escalation 20.50.51.71.10.10.80.4-0.70.40.51.3-0.4-0.3-0.80.1
Intermitt. access day 1 inactive lever presses0.10.10.4-0.30.1-0.3-0.40.5-0.1-0.3-0.10.2-0.3-0.20.6
Intermitt. access day 15 inactive lever presses0.60.62.51.0-0.20.6-0.1-0.0-0.1-0.21.3-0.1-1.0-1.61.0
Intermitt. access escalation Index1.10.92.01.41.21.31.1-0.90.90.81.3-0.80.50.1-0.4
Intermittent access day 1 total infusions0.10.10.20.10.5-0.10.40.20.50.4-0.1-0.1-0.00.1-0.2
Intermittent access day 15 total infusions0.20.30.80.70.20.40.60.10.60.50.9-0.2-0.5-0.70.1
Intermittent access terminal intake (last 3 days)0.30.30.90.70.40.40.7-0.10.70.60.9-0.4-0.2-0.4-0.2
Intermittent access total infusions0.20.20.60.60.20.50.3-0.20.50.50.7-0.3-0.3-0.4-0.0
Intermittent access day 1 locomotion0.20.20.8-0.30.5-0.20.20.30.60.5-0.4-0.20.50.9-0.8
Intermittent access day 15 total locomotion0.00.00.10.3-0.10.3-0.20.00.20.20.4-0.1-0.2-0.1-0.2
Intermittent access total locomotion0.10.10.2-0.4-0.1-0.3-0.30.50.20.2-0.2-0.00.10.3-0.5
Intermittent access standard deviation0.50.51.4-0.2-0.9-0.4-0.60.6-0.7-0.6-0.10.7-1.1-1.20.8
Left kidney weight1.33.75.72.32.12.22.4-2.12.12.02.0-1.71.20.9-1.2
Right kidney weight1.23.35.52.41.92.22.1-1.81.91.92.2-1.71.00.7-1.1
Cocaine induced anxiety0.70.81.6-0.5-1.0-0.8-0.70.8-0.7-0.7-0.81.0-1.2-1.31.1
Post-drug Anxiety0.80.81.71.31.01.21.1-1.20.90.81.1-0.80.3-0.20.0
Baseline Anxiety2.52.74.21.91.92.01.7-2.01.51.41.9-1.71.30.8-0.9
Tail length0.30.82.61.60.51.20.5-1.40.50.61.3-0.4-0.0-0.70.1
Length with tail1.13.97.72.82.12.52.2-2.42.11.92.3-1.50.90.2-1.0
Length without tail1.22.64.51.72.01.72.1-1.21.91.81.6-1.41.10.8-1.2
Times rat made contact with spout2.83.35.02.11.92.01.9-2.11.91.92.2-1.71.40.8-1.2
Lifetime Intake0.10.10.50.5-0.30.4-0.1-0.10.20.20.7-0.2-0.6-0.60.2
Liver weight, left0.00.10.30.30.30.20.3-0.50.20.00.1-0.30.20.10.0
Liver weight, right0.00.10.3-0.00.50.00.4-0.20.30.2-0.2-0.00.30.2-0.1
Locomotor activity0.10.20.50.60.50.40.7-0.60.50.60.3-0.30.40.3-0.2
Locomotor testing distance0.10.20.3-0.2-0.5-0.5-0.40.3-0.4-0.3-0.60.4-0.3-0.30.5
Locomotor testing rearing0.10.10.30.50.10.50.0-0.50.20.20.4-0.30.30.1-0.3
Locomotion in novel chamber1.62.03.6-0.8-1.2-0.9-1.51.0-1.5-1.6-1.11.5-1.7-1.71.9
Locomotion in novel chamber post-restriction1.92.23.7-1.5-1.6-1.5-1.61.4-1.4-1.6-1.91.7-1.4-1.01.3
Fecal boli incidents, locomotor time 11.61.72.7-0.8-1.1-1.3-0.81.2-1.2-1.2-1.41.6-1.6-1.51.7
Change in fecal boli incidents, locomotor task0.10.00.3-0.3-0.20.1-0.5-0.1-0.2-0.20.2-0.10.10.1-0.0
Time >=10cm from walls, locomotor time 10.20.20.3-0.6-0.6-0.4-0.50.5-0.5-0.5-0.40.6-0.5-0.40.4
Bouts of movement, locomotor time 11.51.62.3-1.1-1.0-1.5-0.91.4-1.2-1.3-1.41.5-1.3-1.21.3
Total resting periods, locomotor time 12.32.63.3-1.3-1.4-1.7-1.31.7-1.6-1.7-1.51.8-1.7-1.61.7
Rest time, locomotor task time 10.60.71.2-0.5-0.7-0.6-0.80.5-0.9-1.0-0.40.9-1.0-1.11.1
Distance moved, locomotor task time 10.50.51.3-1.1-0.3-0.9-0.10.90.00.1-1.10.10.61.1-0.9
Vertical activity count, locomotor time 10.90.92.10.70.70.70.8-0.71.11.20.5-1.01.11.2-1.5
Time >=10cm from walls, locomotor time 21.41.52.21.41.31.51.2-1.31.31.31.4-1.20.90.6-1.0
Bouts of movement, locomotor time 20.30.41.10.41.10.21.0-0.40.80.7-0.0-0.30.60.4-0.4
Total resting periods, locomotor time 20.30.31.00.41.00.21.0-0.40.70.70.0-0.20.50.3-0.3
Rest time, locomotor task time 20.10.10.3-0.2-0.2-0.2-0.10.2-0.3-0.3-0.00.4-0.4-0.60.5
Distance moved, locomotor task time 20.40.51.2-1.0-0.7-1.0-0.80.8-0.6-0.5-1.10.4-0.10.3-0.1
Vertical activity count, locomotor time 20.20.20.8-0.00.20.10.0-0.40.30.4-0.2-0.40.60.8-0.9
Light reinforcement 10.30.52.10.2-0.7-0.4-0.60.6-0.5-0.5-0.10.8-1.1-1.50.8
Light reinforcement 20.81.03.6-0.1-0.8-0.4-0.80.6-0.7-0.9-0.31.1-1.5-1.91.4
Bone: marrow area1.12.56.72.61.42.21.3-2.01.31.52.3-1.10.3-0.2-0.1
Bone: maximum diameter0.50.92.31.51.01.20.9-1.00.90.91.4-0.60.2-0.3-0.1
Bone: maximum force0.40.71.51.01.20.81.1-0.81.11.00.4-0.60.50.5-0.6
Bone: maximum moment0.40.71.30.91.10.81.1-0.71.01.00.4-0.60.50.6-0.6
Mean time between licks in bursts0.30.40.8-0.7-0.6-0.6-0.60.7-0.6-0.6-0.90.7-0.5-0.20.5
Mean num. licks in bursts0.40.51.71.00.60.70.6-0.70.60.61.3-0.70.1-0.3-0.1
Cd content in liver1.01.11.60.81.01.11.0-1.11.01.00.9-1.21.21.2-1.0
Co content in liver0.30.41.2-1.1-0.3-0.9-0.30.8-0.4-0.6-0.90.40.10.1-0.2
Cu content in liver0.50.60.8-0.7-0.7-0.8-0.70.8-0.7-0.7-0.60.9-0.8-0.80.9
Fe content in liver0.30.40.91.00.80.80.7-0.60.70.60.6-0.50.40.3-0.3
K content in liver0.90.92.9-1.7-0.3-1.4-0.31.2-0.4-0.4-1.60.50.40.9-0.3
Mg content in liver0.20.20.9-0.70.2-0.30.20.30.20.1-0.6-0.10.61.0-0.5
Mn content in liver2.22.63.3-1.5-1.8-1.4-1.81.5-1.8-1.7-1.31.6-1.6-1.51.7
Na content in liver0.80.82.7-0.40.80.10.8-0.10.80.7-0.1-0.51.41.6-1.5
Rb content in liver0.20.31.1-0.20.60.00.6-0.10.60.4-0.4-0.50.71.0-0.6
Se content in liver0.30.40.90.00.60.20.6-0.30.60.50.2-0.60.90.9-1.0
Sr content in liver0.60.60.8-0.5-0.7-0.7-0.70.8-0.8-0.8-0.70.8-0.8-0.90.7
Zn content in liver0.10.10.3-0.30.1-0.30.10.20.1-0.0-0.50.10.40.3-0.5
Bone: minimum diameter0.50.91.51.21.21.01.0-0.91.01.01.0-0.60.70.3-0.8
Time in familiar zone, hab. session 10.70.71.80.20.50.50.4-0.90.60.70.4-0.91.21.3-1.1
Time in novel zone, hab. session 10.20.20.70.50.10.20.10.0-0.0-0.0-0.00.2-0.6-0.80.8
Total zone transitions, hab. session 10.81.11.8-1.3-1.2-1.4-1.11.1-1.1-1.2-1.01.0-0.8-0.80.7
Total locomotion distance, hab. session 11.72.43.5-1.7-1.6-1.9-1.51.6-1.6-1.6-1.61.5-1.3-1.21.2
Locomotion velocity, hab. session 12.02.84.3-1.9-1.7-2.1-1.71.9-1.8-1.7-1.81.7-1.3-1.21.1
Time in familiar zone, hab. session 20.40.40.7-0.3-0.8-0.4-0.80.4-0.7-0.6-0.20.6-0.8-0.60.8
Time in novel zone, hab. session 20.80.81.21.01.10.91.1-1.01.00.90.7-0.80.80.4-0.7
Total zone transitions, hab. session 20.20.21.0-0.0-0.5-0.2-0.40.5-0.4-0.40.10.4-0.7-1.00.4
Total locomotion distance, hab. session 21.41.84.1-0.7-1.4-0.9-1.41.1-1.3-1.4-0.51.4-1.8-2.01.6
Locomotion velocity, hab. session 21.92.64.2-1.1-1.7-1.3-1.71.5-1.6-1.7-0.91.7-1.9-2.11.7
Novel to familiar place preference ratio0.10.10.20.50.20.50.2-0.40.20.20.3-0.30.10.10.0
Novelty place preference0.10.10.30.50.30.50.3-0.50.30.30.2-0.40.20.3-0.2
Time in novel zone, NPP test0.40.40.80.90.60.90.6-0.90.60.60.6-0.60.40.4-0.3
Total zone transitions, NPP test0.60.91.4-1.0-1.1-1.1-1.01.2-0.9-1.0-0.70.9-0.8-0.90.6
Total locomotion distance, NPP test2.02.84.1-1.3-1.8-1.5-1.81.7-1.7-1.8-1.11.8-1.8-2.01.5
Locomotion velocity, NPP test2.43.44.0-1.7-2.0-1.8-2.02.0-1.9-2.0-1.42.0-1.9-2.01.6
Intraocular pressure1.72.34.4-1.0-1.1-1.3-1.31.3-1.8-1.7-1.41.7-1.7-1.62.1
Delta distance traveled before/after self-admin0.40.42.0-0.40.10.20.3-0.10.10.2-0.3-0.41.11.4-1.2
Delta ambulatory time before/after self-admin0.20.20.9-0.4-0.10.00.10.0-0.1-0.1-0.4-0.10.71.0-0.9
Parametrial fat weight10.921.327.55.25.15.14.8-5.14.95.04.7-4.53.82.8-3.6
Pavlov. Cond. lever latency0.60.82.41.50.41.10.3-0.60.40.41.5-0.4-0.6-1.30.6
Pavlov. Cond. magazine entry latency0.40.62.1-0.20.70.10.7-0.50.60.5-0.6-0.51.21.5-1.0
Pavlov. Cond. change in total contacts0.90.93.2-1.5-0.3-1.1-0.20.5-0.3-0.3-1.80.30.91.6-0.8
Pavlov. Cond. index score0.60.83.5-1.00.3-0.60.40.00.30.2-1.2-0.31.31.9-1.1
Pavlov. Cond. latency score0.60.82.6-1.4-0.1-0.9-0.00.4-0.2-0.2-1.50.20.91.6-0.9
Pavlov. Cond. lever contacts0.40.52.0-0.90.2-0.60.30.10.20.1-0.9-0.11.01.4-0.9
Pavlov. Cond. magazine entry number0.91.13.1-0.1-1.0-0.4-1.10.9-1.0-0.90.30.9-1.5-1.81.3
Pavlov. Cond. intertrial magazine entries2.53.17.2-0.4-2.0-0.7-2.01.3-1.9-1.7-0.11.7-2.3-2.72.0
Pavlov. Cond. lever-magazine prob. diff.0.81.04.3-0.90.5-0.50.6-0.10.40.4-1.1-0.41.42.1-1.3
Pavlov. Cond. response bias0.70.93.4-0.30.80.00.8-0.50.80.7-0.5-0.71.41.8-1.3
Pavlov. Cond. lever latency5.06.88.9-3.0-2.7-2.8-2.72.8-2.7-2.7-2.82.9-2.1-1.52.0
Pavlov. Cond. magazine entry latency1.31.54.32.10.91.61.0-1.61.01.01.6-1.20.1-0.6-0.1
Pavlov. Cond. change in total contacts5.27.19.33.02.72.82.7-2.82.82.82.8-3.12.31.7-2.2
Pavlov. Cond. index score4.86.29.83.12.52.82.5-2.92.62.62.7-2.71.81.1-1.7
Pavlov. Cond. latency score3.84.87.22.72.22.52.2-2.52.22.22.4-2.41.71.0-1.6
Pavlov. Cond. lever contacts4.35.87.62.82.62.62.6-2.62.62.52.5-2.72.01.4-1.9
Pavlov. Cond. magazine entry number2.53.16.4-2.5-1.7-2.1-1.72.1-1.8-1.8-2.21.9-0.9-0.20.9
Pavlov. Cond. intertrial magazine entries0.70.92.2-1.5-0.8-1.1-0.81.2-0.9-0.9-1.31.1-0.30.20.2
Pavlov. Cond. lever-magazine prob. diff.5.46.910.03.22.72.92.7-2.92.72.72.7-2.92.11.4-2.0
Pavlov. Cond. response bias3.75.08.62.92.32.62.3-2.52.32.32.5-2.51.50.7-1.4
Time in closed arm before self-admin0.20.31.0-0.3-0.3-0.4-0.30.6-0.5-0.5-0.10.6-0.5-1.00.6
Time in closed arm after self-admin1.51.63.1-0.8-1.1-1.0-1.41.3-1.4-1.5-0.61.3-1.1-1.81.3
Time in open arm before self-admin0.40.41.30.30.20.40.5-0.70.50.60.2-0.80.61.2-1.0
Time in open arm after self-admin2.32.53.81.31.21.61.4-1.91.71.81.3-1.81.42.0-1.5
Bone: periosteal estimation0.81.63.71.91.41.51.3-1.41.31.41.5-0.90.50.1-0.3
Bone: periosteal perimeter0.10.20.70.80.40.60.3-0.60.30.40.8-0.1-0.2-0.50.2
Bone: post-yield work0.00.10.20.3-0.10.1-0.10.1-0.1-0.20.00.1-0.5-0.40.4
Progressive ratio test 1 active lever presses0.10.10.20.30.30.30.5-0.20.50.40.5-0.50.10.1-0.3
Progressive ratio test 1 breakpoint0.40.40.60.60.60.50.8-0.40.70.70.7-0.80.40.5-0.6
Progressive ratio test 1 inactive lever presses0.30.41.30.3-0.60.2-0.7-0.0-0.3-0.40.50.2-1.0-1.10.9
Progressive ratio test 2 active lever presses0.10.10.20.30.10.10.10.20.40.30.4-0.1-0.2-0.2-0.2
Progressive ratio test 2 breakpoint0.10.10.20.30.30.20.10.20.50.40.4-0.2-0.1-0.0-0.3
Progressive ratio test 2 inactive lever presses0.40.41.70.90.00.60.20.00.30.10.80.3-1.0-1.30.7
Incentive Sensitization - Responses0.10.10.40.2-0.30.1-0.60.4-0.1-0.20.20.3-0.6-0.60.2
Incentive Sensitization - Breakpoint0.10.10.40.3-0.30.3-0.50.2-0.1-0.20.40.1-0.5-0.60.2
Sum of active levers in priming session hrs 5-61.71.72.0-1.1-1.4-1.2-1.41.4-1.4-1.4-0.91.3-1.3-1.41.3
Progressive ratio2.12.43.8-1.3-1.5-1.3-1.51.2-1.8-1.8-1.31.6-1.6-1.61.9
Food seeking constrained by brief footshock0.91.12.6-1.6-1.2-1.3-1.21.3-1.1-1.0-1.10.8-0.20.2-0.1
Seeking ratio, punishment vs. effort1.92.35.50.91.21.01.2-1.01.61.61.1-1.71.92.0-2.3
Retroperitoneal fat weight13.444.259.27.17.77.07.6-6.97.27.06.2-6.75.84.7-5.0
Reaction time number correct1.62.33.1-1.1-1.3-1.4-1.11.3-1.6-1.6-1.71.7-1.7-1.71.8
Reaction time mean minus median2.02.75.32.11.32.01.4-2.11.41.62.3-1.71.20.6-1.1
Reaction time mean minus median AUC1.82.34.62.11.21.91.3-2.11.31.52.1-1.51.00.4-0.8
Reaction time num false alarms2.22.94.3-2.1-1.7-2.1-1.51.9-1.5-1.7-1.81.9-1.5-1.41.2
Reaction time num false alarms AUC1.72.43.7-1.9-1.6-1.8-1.41.8-1.4-1.5-1.61.7-1.3-1.21.0
Reaction time trials correct on left1.62.33.1-1.1-1.3-1.4-1.11.3-1.6-1.6-1.71.7-1.7-1.71.8
Reaction time trials on left1.52.23.1-1.0-1.2-1.3-1.11.3-1.6-1.6-1.71.7-1.7-1.71.8
Reaction time mean3.54.97.72.82.22.52.0-2.52.32.32.8-2.31.61.0-1.5
Reaction time mean AUC2.94.05.82.42.02.21.9-2.22.02.12.4-2.21.51.0-1.3
Median of all reaction times3.04.26.32.52.12.31.9-2.22.22.22.5-2.11.51.0-1.4
Reaction time omissions0.71.02.11.30.71.40.7-1.40.70.71.3-1.10.60.4-0.4
Reaction time false alarm rate0.50.61.4-1.2-0.9-1.0-0.81.0-0.6-0.7-0.60.8-0.5-0.50.2
Reaction time premature initiation rate0.10.20.60.0-0.4-0.3-0.40.3-0.2-0.10.20.5-0.4-0.80.5
Reaction time premature initiations0.91.32.5-0.6-1.1-1.1-1.01.0-1.1-0.9-0.71.4-1.3-1.61.4
Std. dev. reaction times2.53.65.92.41.72.21.7-2.21.81.92.4-2.01.40.9-1.3
Reaction time trials completed1.52.23.1-1.0-1.2-1.3-1.11.3-1.6-1.6-1.71.7-1.7-1.71.8
Reaction time trials AUC1.72.53.8-0.9-1.3-1.3-1.11.3-1.6-1.6-1.61.8-1.9-1.92.0
Run reversals in cocaine runway, females2.32.22.81.61.61.71.6-1.61.61.61.4-1.61.31.1-1.2
Run reversals in cocaine runway, males3.23.15.91.31.51.41.7-1.52.02.01.3-1.72.01.9-2.4
Latency to leave start box in cocaine runway1.01.12.2-0.7-0.6-0.8-0.81.0-1.1-1.1-1.11.2-1.2-1.21.5
Latency to leave start box in cocaine runway, F0.30.31.20.20.1-0.1-0.20.4-0.3-0.3-0.20.6-1.0-1.11.1
Latency to leave start box in cocaine runway, M1.01.01.5-1.2-1.1-1.1-1.21.0-1.2-1.1-1.10.8-0.5-0.20.5
Std. dev. time between licks in bursts0.60.81.6-1.1-0.9-1.0-0.90.7-0.9-0.9-1.30.9-0.6-0.30.7
Total sessions with >9 infusions0.70.82.11.00.21.20.3-1.10.80.91.4-1.00.50.4-1.0
Short access day 1 total inactive lever presses2.02.24.9-0.6-1.4-0.7-1.81.2-1.3-1.4-0.51.5-2.0-2.22.1
Short access day 10 total inactive lever presses0.20.20.50.70.30.6-0.2-0.40.10.10.6-0.1-0.2-0.40.6
Short access day 1 total infusions1.01.02.1-0.5-1.4-0.5-1.40.5-1.0-1.0-0.40.8-1.3-1.31.1
Short access day 10 total infusions0.00.00.10.2-0.00.10.0-0.00.10.20.1-0.0-0.3-0.2-0.0
Short access total infusions0.10.10.50.5-0.20.6-0.0-0.40.20.20.7-0.4-0.1-0.1-0.2
Short access day 1 locomotion0.20.20.60.4-0.20.70.1-0.70.30.40.7-0.50.20.1-0.6
Short access day 10 total locomotion0.30.30.7-0.8-0.5-0.8-0.50.8-0.4-0.3-0.80.6-0.3-0.20.2
Short access total locomotion0.20.21.1-0.2-0.20.1-0.1-0.10.40.50.1-0.40.50.8-1.1
One hour access (0.3 mA shock)0.70.82.1-0.6-1.4-0.6-1.20.9-1.1-0.9-0.30.7-1.2-0.90.7
Compulsive drug intake1.81.83.8-0.9-1.7-0.9-1.81.0-1.9-1.9-0.51.0-1.1-1.01.2
One hour access (shock baseline)0.20.30.80.50.40.40.6-0.40.80.90.5-0.50.10.2-0.5
Social response proportion4.34.66.52.02.42.42.4-2.62.12.12.2-2.31.91.7-1.6
Social responses0.30.41.30.41.00.41.1-0.50.80.80.2-0.60.50.5-0.4
Social time1.62.14.21.21.81.22.1-1.31.81.60.7-1.21.31.3-1.3
Soleus weight0.00.10.20.40.20.40.2-0.30.20.30.1-0.10.1-0.00.1
Bone: stiffness0.10.10.30.50.60.30.5-0.20.40.4-0.10.2-0.1-0.10.2
Tibialis anterior weight1.03.34.62.01.82.11.8-2.21.81.81.8-2.11.51.3-1.5
Time to tail flick, vehicle, before self-admin0.80.82.71.60.81.20.5-1.00.30.21.4-0.5-0.3-1.10.8
Time to tail flick, vehicle, after self-admin0.30.30.8-0.8-0.3-0.9-0.50.8-0.3-0.3-0.70.6-0.2-0.40.4
Time to tail flick, test, before self-admin0.30.30.9-0.4-1.0-0.5-1.00.4-0.6-0.5-0.10.3-0.5-0.50.4
Time to tail flick, test, after self-admin1.91.95.6-0.1-1.3-0.5-1.20.7-1.2-1.2-0.11.2-2.1-2.42.1
Delta time to tail flick, vehicle, before/after SA1.01.02.3-1.5-1.0-1.4-1.01.3-0.6-0.6-1.31.0-0.5-0.20.3
Delta time to tail flick, test, before/after SA0.60.61.80.1-0.4-0.2-0.30.3-0.6-0.6-0.20.8-1.3-1.31.3
Tibia length2.46.68.62.92.92.62.9-2.62.82.82.8-2.42.21.5-2.0
Ambulatory time before self-admin0.40.40.70.70.50.60.7-0.70.80.70.8-0.70.40.4-0.3
Ambulatory time after self-admin0.20.21.2-0.4-0.00.00.1-0.20.10.1-0.3-0.20.71.1-0.7
Bone: tissue strength1.71.72.01.41.21.31.3-1.41.31.31.3-1.41.31.1-1.3
Total heroin consumption1.31.63.4-0.5-1.2-0.7-1.30.8-1.3-1.3-0.51.3-1.6-1.81.8
Bone: trabecular number0.20.30.7-0.8-0.5-0.7-0.50.5-0.6-0.5-0.80.5-0.4-0.10.5
Bone: trabecular spacing1.51.92.61.61.61.31.5-1.11.51.51.4-1.51.21.0-1.2
Bone: trabecular thickness0.10.10.3-0.4-0.1-0.4-0.10.3-0.1-0.2-0.60.4-0.1-0.10.2
Bone: trabecular tissue density1.01.42.30.71.20.91.2-0.91.31.30.8-1.31.41.5-1.3
Water consumed over 24 hours0.20.21.00.50.00.40.1-0.40.10.00.60.2-0.5-1.00.6
Number of responses in last shaping day0.80.82.0-0.3-1.2-0.3-1.20.6-0.8-0.80.30.6-1.2-1.41.0