Hub : Genes

LOC102550304

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Liver intron excision ratio chr3_151976874_151977433 0.04 0.03 1.1e-03 0.02 0.02 0.01 0.01 3.6e-03 6.6e-03 2.6e-02 9.8e-03
2 Liver intron excision ratio chr3_151976874_151977256 0.04 0.03 9.7e-04 0.01 0.02 0.01 0.01 1.1e-02 5.7e-03 3.0e-02 1.0e-02
3 BLA gene expression LOC102550304 0.7 0.13 0.0e+00 0.55 0.37 0.54 0.55 3.8e-34 1.2e-20 4.0e-33 2.3e-34
4 pVTA gene expression LOC102550304 0.43 0.11 0.0e+00 0.48 0.47 0.49 0.49 3.7e-43 2.0e-42 9.4e-45 1.6e-44
5 NAcc gene expression LOC102550304 0.31 0.1 0.0e+00 0.38 0.33 0.39 0.38 8.1e-62 6.6e-51 1.3e-62 2.6e-60
6 Brain gene expression LOC102550304 0.5 0.11 0.0e+00 0.62 0.6 0.62 0.62 1.7e-73 4.4e-69 3.9e-74 1.3e-72
7 LHb gene expression LOC102550304 0.53 0.15 1.8e-11 0.37 0.35 0.34 0.24 9.3e-10 3.1e-09 4.9e-09 1.9e-06
8 IC gene expression LOC102550304 0.6 0.17 0.0e+00 0.47 0.47 0.46 0.48 4.2e-22 7.3e-22 2.3e-21 1.5e-22
9 OFC gene expression LOC102550304 0.64 0.13 1.6e-15 0.52 0.48 0.53 0.5 2.4e-14 3.2e-13 1.1e-14 1.1e-13
10 Adipose gene expression LOC102550304 0.65 0.12 0.0e+00 0.41 0.43 0.43 0.43 3.2e-49 1.5e-51 9.6e-52 1.9e-51
11 PL gene expression LOC102550304 0.57 0.1 0.0e+00 0.64 0.45 0.64 0.63 8.4e-92 1.4e-54 2.6e-90 2.9e-89
12 RMTg gene expression LOC102550304 0.22 0.12 8.2e-05 0.1 0.12 0.1 0.09 1.4e-03 5.8e-04 1.6e-03 2.3e-03
13 Liver gene expression LOC102550304 0.51 0.13 0.0e+00 0.39 0.38 0.39 0.38 1.5e-45 1.8e-44 4.6e-46 1.7e-44
14 IL gene expression LOC102550304 0.53 0.18 7.1e-10 0.26 0.3 0.4 0.3 6.7e-07 6.4e-08 1.6e-10 4.5e-08

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14
Bone: apparent density0.00.00.2-0.4-0.2-0.10.00.00.1-0.00.00.00.10.0-0.00.1-0.4
Area under the delay curve0.20.32.0-1.4-0.70.2-0.2-0.20.2-0.20.3-0.40.1-0.3-0.0-0.1-1.1
BMI with tail10.235.641.46.26.46.4-6.2-6.2-6.2-6.16.2-6.3-6.1-6.16.1-5.7-2.0
BMI without tail5.127.331.95.35.65.7-5.6-5.6-5.4-5.35.6-5.5-5.3-5.45.3-4.6-1.4
Body weight11.550.363.07.87.97.7-7.4-7.4-7.4-7.37.2-7.2-7.3-7.37.1-6.7-0.9
Weight adjusted by age0.10.22.2-0.4-0.10.00.30.30.2-0.4-0.20.50.10.3-0.3-0.11.5
Bone surface0.20.30.50.70.70.4-0.7-0.7-0.6-0.40.6-0.6-0.5-0.50.6-0.40.0
Bone volume0.00.00.10.30.30.2-0.3-0.2-0.2-0.10.2-0.2-0.1-0.10.2-0.00.3
Breakpoint value in progressive ratio session0.10.20.40.60.60.4-0.5-0.5-0.5-0.40.4-0.5-0.4-0.40.5-0.40.0
Number of licking bursts0.10.20.60.10.20.3-0.4-0.4-0.4-0.30.5-0.5-0.4-0.50.4-0.1-0.8
Context. condit. distance diff. score0.00.00.20.20.1-0.10.00.0-0.0-0.10.00.2-0.10.00.0-0.00.4
Locomotion velocity, session 11.61.82.3-1.3-1.2-1.51.31.31.41.5-1.41.21.41.4-1.51.31.1
Locomotion distance, session 14.25.46.8-2.5-2.4-2.62.32.32.42.6-2.42.32.42.3-2.42.20.7
Locomotion velocity, session 21.31.63.3-1.8-1.6-1.31.31.31.31.2-1.21.01.31.2-1.31.0-0.3
Locomotion distance, session 25.98.29.8-2.7-2.8-3.12.92.92.93.1-2.92.92.92.9-3.03.01.8
Locomotion velocity, session 33.33.85.1-2.1-2.1-2.12.02.02.02.3-2.01.82.02.0-1.92.00.1
Locomotion distance, session 31.01.21.7-1.3-1.3-1.11.11.11.11.1-1.10.71.11.1-1.01.2-0.5
Stereotopy head waving bouts, day 30.00.00.10.20.0-0.20.10.10.10.3-0.20.10.20.2-0.20.20.3
Stereotopy head waving duration, day 30.00.00.20.40.30.0-0.1-0.1-0.10.00.1-0.0-0.1-0.10.0-0.10.3
Locomotion velocity, session 71.31.51.9-1.0-1.0-1.31.21.21.21.4-1.31.21.31.3-1.30.91.0
Locomotion distance, session 70.30.41.3-0.1-0.2-0.80.50.50.50.7-0.60.80.60.6-0.70.41.1
Stereotopy head waving bouts, day 70.20.30.40.30.40.6-0.5-0.5-0.5-0.50.5-0.7-0.5-0.50.5-0.6-0.7
Stereotopy head waving duration, day 70.10.10.2-0.5-0.3-0.10.30.20.30.2-0.20.00.30.2-0.10.1-0.4
Locomotion velocity, session 81.21.51.9-1.0-1.0-1.31.21.21.21.4-1.31.41.31.3-1.41.01.0
Locomotion distance, session 82.94.25.7-1.8-1.9-2.42.02.02.02.1-2.02.42.02.0-2.22.01.5
Degree of sensitization distance0.50.51.81.11.10.5-0.7-0.6-0.6-0.50.5-0.2-0.6-0.60.4-0.81.3
Degree of sensitization stereotypy0.50.50.70.50.70.8-0.7-0.7-0.7-0.80.7-0.8-0.8-0.70.8-0.8-0.5
Conditioned locomotion0.30.31.4-0.3-0.2-0.30.50.50.50.5-0.50.50.40.5-0.60.71.2
Cocaine response after cond. corrected1.52.23.0-1.0-1.3-1.71.51.51.41.5-1.51.71.41.6-1.61.41.6
Cocaine response after cond. not corrected2.33.34.2-1.5-1.7-2.01.81.91.91.9-1.82.01.81.9-1.91.71.6
Cocaine response before conditioning0.10.10.4-0.6-0.5-0.20.20.20.30.4-0.20.10.40.2-0.30.3-0.4
Saline control response0.50.76.71.10.9-0.1-0.4-0.3-0.30.10.20.3-0.1-0.1-0.1-0.02.6
Bone: connectivity density0.10.20.5-0.7-0.6-0.50.30.30.40.4-0.30.40.40.3-0.40.5-0.2
Bone: cortical apparent density0.10.20.7-0.7-0.7-0.30.30.30.30.2-0.20.30.30.2-0.20.0-0.8
Bone: cortical area0.40.71.00.50.60.8-1.0-0.9-0.8-0.81.0-1.0-0.7-0.90.7-0.8-0.7
Bone: cortical porosity0.50.60.90.50.50.8-0.7-0.7-0.7-0.90.8-0.7-0.8-0.80.6-0.6-0.9
Bone: cortical porosity0.70.81.10.80.81.0-1.0-1.0-0.9-1.01.0-0.9-1.0-1.00.8-0.6-0.7
Bone: cortical thickness0.61.14.7-0.00.30.9-1.0-1.0-0.8-0.91.1-1.1-0.8-1.10.8-1.0-2.2
Bone: cortical thickness0.30.31.5-1.2-0.8-0.20.30.30.4-0.1-0.20.10.40.2-0.40.0-1.2
Bone: cortical tissue density0.10.20.5-0.6-0.7-0.40.40.40.40.3-0.30.40.40.3-0.30.1-0.7
Condit. Reinf. active minus inactive responses0.00.00.4-0.0-0.2-0.10.20.20.10.1-0.10.00.10.1-0.00.4-0.6
Condit. Reinf. active-inactive response ratio0.00.00.2-0.2-0.2-0.00.20.20.20.1-0.1-0.00.10.1-0.10.5-0.4
Condit. Reinf. active responses0.10.10.2-0.2-0.3-0.30.30.30.30.2-0.30.20.20.3-0.20.4-0.5
Condit. Reinf. inactive responses0.00.00.10.10.1-0.20.00.00.00.1-0.10.10.10.1-0.1-0.10.4
Incentive salience index mean0.20.32.1-0.7-0.7-0.30.40.40.40.3-0.30.00.30.3-0.20.5-1.5
Condit. Reinf. lever presses0.30.55.4-0.6-0.40.2-0.1-0.1-0.1-0.20.2-0.5-0.2-0.20.3-0.3-2.3
Condit. Reinf. active minus inactive responses0.71.02.11.51.30.8-1.0-1.0-1.0-1.10.9-0.7-1.0-0.90.8-1.10.7
Condit. Reinf. active-inactive response ratio0.60.91.41.21.20.8-0.9-0.9-1.0-1.10.9-0.7-1.1-0.90.9-0.90.4
Condit. Reinf. active responses0.81.11.91.11.11.0-1.1-1.0-1.1-1.21.1-1.1-1.1-1.01.0-1.4-0.4
Condit. Reinf. inactive responses0.40.52.50.20.30.7-0.5-0.6-0.5-0.50.6-0.9-0.5-0.60.7-1.0-1.6
Condit. Reinf. lever presses2.43.55.02.22.21.8-2.0-1.9-2.0-1.81.9-1.7-2.0-1.81.9-1.9-0.6
Condit. Reinf. lever reinforcers received0.91.32.01.31.21.1-1.1-1.1-1.2-1.21.1-1.1-1.1-1.11.1-1.4-0.4
Conditioned reinforcement - actives0.72.96.3-0.5-1.0-1.91.41.41.52.5-1.62.01.81.4-1.82.21.9
Conditioned reinforcement - inactives1.64.38.0-0.7-1.3-2.11.92.01.92.3-2.12.62.02.0-2.12.32.8
Conditioned locomotion0.71.12.9-0.9-1.0-1.20.70.70.91.7-0.81.11.20.6-0.91.4-0.7
Patch foraging indifference point 0 sec0.51.53.2-0.1-0.5-1.41.21.21.11.3-1.41.51.11.4-1.21.01.8
Patch foraging indifference point AUC0.30.81.7-1.3-1.3-1.00.80.80.80.7-0.70.60.80.6-0.80.8-0.9
Delay disc. indifference point, 0s delay1.21.34.10.10.61.2-1.1-1.1-1.0-1.11.2-1.2-1.0-1.31.1-1.1-2.0
Delay disc. indifference point, 16s delay0.50.82.6-1.6-1.3-0.80.70.70.90.8-0.60.50.90.6-0.80.8-0.8
Delay disc. indifference point, 2s delay1.71.93.00.20.91.5-1.5-1.5-1.2-1.41.6-1.6-1.2-1.71.3-1.2-1.7
Delay disc. indifference point, 24s delay1.52.46.2-2.5-2.0-1.31.41.51.71.4-1.31.01.71.6-1.61.1-0.0
Delay disc. indifference point, 4s delay1.31.42.30.00.71.3-1.4-1.4-1.0-1.21.4-1.5-1.0-1.51.1-1.1-1.1
Delay disc. indifference point, 8s delay0.30.52.9-1.7-1.1-0.30.50.50.80.2-0.40.20.70.4-0.70.4-0.2
Indifference point function ln k0.10.21.60.10.30.20.20.20.20.1-0.30.10.30.4-0.3-0.01.3
Indifference point function log k0.10.21.60.10.30.20.20.20.20.1-0.30.10.30.4-0.3-0.01.3
Patch foraging total patch changes 0 sec0.61.93.0-0.4-0.7-1.51.41.41.31.5-1.61.71.31.5-1.41.21.7
Patch foraging total patch changes 12 sec0.10.10.20.30.40.1-0.4-0.4-0.4-0.30.4-0.2-0.3-0.40.2-0.50.1
Patch foraging total patch changes 18 sec1.12.53.8-1.1-1.4-1.91.71.71.51.7-1.71.91.61.6-1.61.61.1
Patch foraging total patch changes 24 sec0.10.30.7-0.2-0.4-0.80.50.50.40.5-0.50.80.40.5-0.50.60.3
Patch foraging total patch changes 6 sec0.40.61.1-0.3-0.5-1.00.90.90.70.8-0.91.00.70.9-0.70.70.4
Patch foraging time to switch 0 sec0.93.54.51.81.92.1-1.9-1.9-2.0-2.11.9-1.7-2.0-1.91.9-2.1-0.3
Patch foraging water rate 0 sec1.03.94.8-2.0-2.1-2.22.12.12.12.1-2.01.92.02.0-2.02.1-0.0
Patch foraging water rate 12 sec1.04.06.3-2.5-2.4-2.02.02.02.12.2-1.91.82.11.9-1.91.9-0.6
Patch foraging water rate 18 sec5.211.613.2-3.6-3.5-3.43.63.53.63.3-3.53.43.63.4-3.63.12.3
Patch foraging water rate 24 sec3.95.66.6-2.3-2.3-2.52.42.42.42.3-2.42.42.32.5-2.52.61.4
Patch foraging water rate 6 sec4.26.27.4-2.7-2.7-2.52.62.62.62.5-2.62.32.62.6-2.62.40.8
Seeking ratio, delayed vs. immediate footshock0.10.20.70.80.60.6-0.2-0.2-0.4-0.70.2-0.3-0.5-0.10.3-0.30.3
Distance traveled before self-admin0.30.71.40.40.70.9-0.9-1.0-0.9-0.71.0-1.2-0.9-1.00.9-0.6-0.9
Distance traveled after self-admin0.10.21.0-1.0-0.7-0.20.30.30.30.2-0.20.20.20.2-0.20.5-0.6
Extensor digitorum longus weight0.10.30.70.80.80.7-0.5-0.4-0.5-0.30.4-0.6-0.4-0.40.4-0.40.7
Bone: elastic displacement0.60.72.00.50.70.8-0.7-0.7-0.8-0.80.7-0.8-0.9-0.80.8-1.2-1.4
Bone: elastic work4.05.36.01.82.12.5-2.3-2.3-2.3-2.52.3-2.4-2.3-2.42.3-2.4-2.1
Bone: endosteal estimation1.33.16.52.62.41.6-1.7-1.7-1.7-1.51.6-1.5-1.6-1.41.6-1.22.0
Bone: endosteal perimeter0.20.64.91.21.00.1-0.4-0.4-0.3-0.20.2-0.1-0.2-0.20.20.22.2
Epididymis fat weight6.130.639.66.06.36.1-5.7-5.7-5.7-5.75.6-5.7-5.8-5.55.5-5.2-0.9
Delta time in closed arm before/after self-admin0.20.20.4-0.4-0.5-0.40.60.60.50.1-0.60.50.40.6-0.50.00.2
Delta time in open arm before/after self-admin1.41.73.01.71.51.2-1.4-1.4-1.4-0.91.3-1.4-1.3-1.21.5-0.8-0.3
Diff in mean of infusions in LGA sessions0.30.52.80.10.20.6-0.5-0.6-0.6-0.60.6-0.8-0.6-0.70.8-0.6-1.7
Delay discount exponential model param0.20.32.41.60.8-0.1-0.0-0.0-0.40.0-0.10.3-0.30.10.2-0.00.9
Extinction: sum of active levers before priming0.30.50.8-0.4-0.5-0.60.90.80.70.5-0.90.60.70.9-0.70.60.9
Active lever presses in extinction session 61.21.22.01.41.40.9-1.3-1.3-1.2-0.81.2-1.0-1.1-1.21.0-1.0-0.1
Bone: final force0.61.01.50.81.01.2-1.1-1.1-1.0-1.11.2-1.2-1.0-1.11.0-0.8-0.6
Bone: final moment0.50.91.30.70.91.0-1.0-1.0-0.9-1.01.0-1.1-0.9-1.00.9-0.8-0.6
Food consumed during 24 hour testing period0.10.30.40.50.60.5-0.7-0.7-0.6-0.30.6-0.6-0.4-0.60.4-0.60.4
Glucose0.50.81.91.41.31.0-0.8-0.8-0.9-0.80.7-0.9-0.8-0.70.7-0.80.5
Heart weight1.21.93.01.41.71.3-1.7-1.7-1.4-1.11.7-1.2-1.3-1.61.2-1.10.4
Delay discount hyperbolic model param0.20.31.41.20.4-0.40.40.4-0.00.4-0.50.60.00.5-0.10.31.0
Intermittent access intake day 1-15 change0.10.72.41.51.20.5-1.0-0.9-0.8-0.20.8-0.4-0.8-0.90.7-0.50.3
Intermittent access intake escalation0.10.41.71.31.00.4-0.8-0.7-0.6-0.00.6-0.3-0.5-0.70.5-0.40.2
Intermittent access intake escalation 20.40.72.21.51.20.6-1.0-1.0-0.9-0.20.9-0.7-0.8-0.90.8-0.4-0.3
Intermitt. access day 1 inactive lever presses0.11.16.6-0.6-0.5-0.51.01.00.90.3-1.10.80.91.0-1.00.22.6
Intermitt. access day 15 inactive lever presses0.21.16.91.10.3-0.70.70.70.50.8-1.01.10.70.9-0.70.62.6
Intermitt. access escalation Index0.20.61.00.50.70.9-0.7-0.7-0.8-1.00.8-0.8-0.9-0.70.8-0.90.0
Intermittent access day 1 total infusions0.00.10.30.10.20.3-0.3-0.3-0.2-0.30.2-0.2-0.1-0.20.1-0.30.5
Intermittent access day 15 total infusions0.30.71.71.31.10.7-1.0-1.0-0.8-0.40.8-0.5-0.6-0.90.5-0.80.8
Intermittent access terminal intake (last 3 days)0.61.02.41.61.30.9-1.2-1.2-1.1-0.61.0-0.8-0.9-1.10.8-1.00.3
Intermittent access total infusions0.30.31.11.10.80.4-0.6-0.6-0.6-0.20.5-0.3-0.4-0.60.4-0.30.5
Intermittent access day 1 locomotion0.10.10.7-0.9-0.50.0-0.1-0.10.20.20.1-0.10.3-0.2-0.20.1-0.4
Intermittent access day 15 total locomotion0.10.20.40.60.50.1-0.6-0.6-0.50.20.50.0-0.3-0.60.30.1-0.7
Intermittent access total locomotion0.10.10.5-0.3-0.3-0.3-0.1-0.10.10.60.00.30.3-0.2-0.20.5-0.7
Intermittent access standard deviation0.00.20.80.1-0.2-0.60.40.40.40.9-0.50.60.50.5-0.40.50.4
Left kidney weight0.75.78.32.92.82.5-2.5-2.5-2.5-2.32.4-2.4-2.4-2.52.4-2.20.0
Right kidney weight0.21.42.91.71.51.2-1.3-1.2-1.2-0.81.3-1.1-1.1-1.21.2-0.90.4
Cocaine induced anxiety0.20.40.6-0.6-0.6-0.60.60.60.70.7-0.60.60.70.6-0.70.80.7
Post-drug Anxiety0.60.71.70.80.91.0-0.6-0.6-0.8-1.30.7-0.8-0.8-0.60.7-1.00.4
Baseline Anxiety2.64.47.51.92.12.3-1.9-1.9-2.1-2.72.0-2.1-2.2-1.92.2-2.5-0.7
Tail length0.41.92.81.51.71.5-1.5-1.5-1.5-1.31.5-1.3-1.5-1.51.3-1.00.3
Length with tail1.98.412.83.53.63.1-3.0-3.0-3.0-2.92.9-2.7-3.0-3.02.7-2.60.9
Length without tail1.15.78.62.92.82.6-2.4-2.4-2.5-2.52.3-2.2-2.4-2.42.3-2.40.4
Times rat made contact with spout2.93.34.62.12.11.7-2.0-2.0-2.0-1.81.9-1.7-1.9-1.91.8-1.7-0.1
Lifetime Intake0.10.20.80.90.60.1-0.4-0.4-0.40.20.3-0.1-0.2-0.40.3-0.00.2
Liver weight, left1.62.84.32.12.01.8-1.6-1.6-1.6-1.91.6-1.5-1.7-1.51.5-1.81.2
Liver weight, right2.03.44.82.12.22.1-1.8-1.8-1.8-2.11.8-2.1-1.8-1.71.7-1.61.0
Locomotor activity0.10.20.40.40.50.5-0.5-0.5-0.5-0.60.4-0.6-0.5-0.40.4-0.40.1
Locomotor testing distance0.00.10.2-0.5-0.4-0.40.20.20.20.2-0.20.20.30.2-0.30.30.0
Locomotor testing rearing0.00.00.10.10.1-0.2-0.2-0.2-0.3-0.20.20.1-0.2-0.20.10.1-0.1
Locomotion in novel chamber2.12.83.8-1.5-1.5-1.61.91.81.71.1-1.91.81.61.8-1.61.61.9
Locomotion in novel chamber post-restriction1.13.34.4-1.9-1.8-1.71.81.81.82.1-1.91.81.91.7-1.82.11.0
Fecal boli incidents, locomotor time 10.61.53.7-1.1-0.9-0.91.11.11.31.2-1.21.11.31.2-1.41.31.9
Change in fecal boli incidents, locomotor task0.10.10.3-0.1-0.3-0.50.50.50.30.2-0.50.40.30.5-0.20.30.2
Time >=10cm from walls, locomotor time 10.30.40.6-0.6-0.6-0.50.60.60.70.7-0.60.50.60.7-0.60.70.3
Bouts of movement, locomotor time 11.11.41.9-1.2-1.2-1.11.21.11.21.3-1.21.31.21.0-1.41.11.0
Total resting periods, locomotor time 12.02.32.9-1.4-1.5-1.51.61.51.61.7-1.61.71.61.5-1.71.41.3
Rest time, locomotor task time 10.60.92.5-0.3-0.5-0.91.01.00.90.9-1.01.10.81.0-1.00.91.6
Distance moved, locomotor task time 10.20.54.0-1.2-0.8-0.30.10.10.30.30.1-0.30.40.0-0.20.0-2.0
Vertical activity count, locomotor time 10.10.92.10.40.60.9-1.1-1.1-0.9-0.61.1-1.1-0.7-1.01.0-0.7-1.4
Time >=10cm from walls, locomotor time 20.51.41.81.31.41.3-1.2-1.2-1.2-1.21.2-1.2-1.2-1.21.1-1.20.2
Bouts of movement, locomotor time 20.10.40.90.20.40.6-0.6-0.6-0.6-0.90.7-0.7-0.6-0.60.4-0.70.5
Total resting periods, locomotor time 20.10.40.80.30.40.6-0.6-0.6-0.6-0.90.7-0.6-0.6-0.60.4-0.70.7
Rest time, locomotor task time 20.10.10.4-0.1-0.1-0.10.30.30.30.3-0.30.30.20.4-0.30.20.6
Distance moved, locomotor task time 20.30.40.9-1.0-0.9-0.60.50.50.50.4-0.40.30.60.4-0.50.4-0.9
Vertical activity count, locomotor time 20.00.10.5-0.1-0.10.2-0.3-0.3-0.2-0.20.4-0.5-0.2-0.30.3-0.1-0.7
Light reinforcement 10.10.41.70.1-0.1-0.70.30.30.40.9-0.40.90.60.4-0.60.71.3
Light reinforcement 20.41.04.3-0.1-0.3-0.80.70.80.81.1-0.91.10.80.8-1.01.12.1
Bone: marrow area1.23.06.42.52.41.6-1.7-1.7-1.7-1.51.5-1.5-1.5-1.41.5-1.12.1
Bone: maximum diameter0.51.02.51.61.40.7-1.1-1.1-1.0-0.71.0-0.8-0.9-0.90.8-0.51.2
Bone: maximum force0.40.81.10.80.81.0-1.0-0.9-0.8-0.91.0-1.1-0.8-0.90.8-0.6-0.7
Bone: maximum moment0.40.71.00.70.80.9-0.9-0.9-0.8-0.80.9-1.0-0.8-0.90.8-0.7-0.9
Mean time between licks in bursts0.10.40.5-0.7-0.7-0.60.60.60.60.5-0.60.60.60.6-0.50.70.6
Mean num. licks in bursts0.20.61.31.11.10.6-0.7-0.7-0.8-0.60.6-0.5-0.7-0.60.6-0.90.7
Cd content in liver0.10.10.20.10.30.5-0.2-0.2-0.2-0.30.2-0.5-0.3-0.20.4-0.4-0.3
Co content in liver0.40.50.7-0.8-0.6-0.70.70.80.70.6-0.80.80.80.8-0.80.30.8
Cu content in liver0.30.40.5-0.6-0.6-0.60.60.60.60.6-0.60.50.70.6-0.70.40.7
Fe content in liver1.61.92.61.31.31.5-1.4-1.4-1.4-1.61.5-1.5-1.4-1.41.4-1.4-0.7
K content in liver0.80.83.2-1.8-1.3-0.50.70.70.80.4-0.50.50.70.6-0.60.3-1.6
Mg content in liver0.00.00.2-0.2-0.10.2-0.0-0.0-0.0-0.20.1-0.1-0.1-0.00.2-0.2-0.5
Mn content in liver2.22.44.5-1.2-1.2-1.61.51.51.51.7-1.51.61.51.6-1.51.62.1
Na content in liver0.50.63.5-0.10.10.5-0.6-0.6-0.6-0.80.7-0.6-0.6-0.70.6-0.8-1.9
Rb content in liver0.40.50.90.60.50.9-0.6-0.6-0.6-0.80.7-0.8-0.6-0.60.7-1.0-0.3
Se content in liver0.70.81.30.30.60.9-0.9-0.9-0.8-1.00.9-1.0-0.8-0.90.8-1.1-1.0
Sr content in liver0.90.80.9-0.7-0.8-1.00.80.80.90.9-0.90.90.90.9-0.90.90.7
Zn content in liver0.10.10.5-0.7-0.5-0.10.20.20.2-0.0-0.10.10.20.1-0.30.0-0.5
Bone: minimum diameter0.40.81.11.11.10.9-1.0-1.0-1.0-0.81.0-0.9-0.9-0.90.9-0.70.0
Time in familiar zone, hab. session 10.50.52.90.40.30.5-0.5-0.5-0.6-0.60.6-0.9-0.6-0.50.8-0.6-1.7
Time in novel zone, hab. session 10.20.22.10.20.30.2-0.1-0.1-0.0-0.10.10.1-0.0-0.1-0.10.31.4
Total zone transitions, hab. session 10.91.31.6-1.3-1.2-1.21.21.21.21.2-1.21.01.21.2-1.21.10.2
Total locomotion distance, hab. session 11.62.22.6-1.6-1.6-1.61.61.61.61.4-1.61.41.61.5-1.61.20.7
Locomotion velocity, hab. session 12.02.93.5-1.9-1.9-1.81.81.81.81.7-1.81.71.81.7-1.81.40.4
Time in familiar zone, hab. session 20.40.41.0-0.3-0.6-0.80.60.60.60.9-0.60.60.60.7-0.61.00.1
Time in novel zone, hab. session 20.90.91.30.91.11.1-1.0-1.0-1.0-1.20.9-0.9-1.0-1.00.9-1.20.4
Total zone transitions, hab. session 20.20.31.5-0.2-0.2-0.60.30.40.40.6-0.40.70.40.4-0.50.51.2
Total locomotion distance, hab. session 21.52.05.0-0.8-0.9-1.51.31.31.31.4-1.41.61.31.3-1.51.52.2
Locomotion velocity, hab. session 22.12.94.4-1.3-1.4-1.81.61.61.71.7-1.71.91.71.7-1.81.72.1
Novel to familiar place preference ratio0.00.10.20.40.30.1-0.1-0.2-0.2-0.40.1-0.0-0.3-0.10.20.1-0.1
Novelty place preference0.10.10.20.40.30.2-0.2-0.2-0.3-0.50.2-0.2-0.4-0.20.40.1-0.4
Time in novel zone, NPP test0.30.30.60.80.60.5-0.5-0.5-0.6-0.80.5-0.4-0.7-0.50.6-0.2-0.3
Total zone transitions, NPP test0.71.11.5-1.1-1.0-1.20.91.01.01.2-1.01.11.11.0-1.11.00.8
Total locomotion distance, NPP test2.23.14.0-1.4-1.5-2.01.71.71.71.8-1.71.91.81.7-1.91.82.0
Locomotion velocity, NPP test2.73.84.8-1.8-1.8-2.21.91.91.92.0-1.92.12.01.9-2.11.91.8
Intraocular pressure1.01.63.5-1.0-0.9-0.91.61.51.30.4-1.51.21.21.6-1.30.91.9
Delta distance traveled before/after self-admin0.80.91.5-1.2-1.2-1.01.00.90.90.9-0.91.10.80.9-0.71.1-0.4
Delta ambulatory time before/after self-admin0.50.81.3-1.0-1.1-1.00.90.90.91.0-0.81.10.80.8-0.71.1-0.4
Parametrial fat weight19.846.760.67.87.77.2-7.1-7.1-7.1-7.06.9-6.8-7.0-6.86.9-6.6-0.9
Pavlov. Cond. lever latency0.60.84.61.71.30.4-0.6-0.6-0.6-0.40.4-0.1-0.5-0.40.4-0.42.1
Pavlov. Cond. magazine entry latency0.70.94.90.10.31.1-0.6-0.6-0.6-0.90.7-1.2-0.8-0.60.8-0.8-2.2
Pavlov. Cond. change in total contacts0.90.97.4-1.5-1.3-0.10.60.50.50.2-0.3-0.20.40.3-0.20.2-2.7
Pavlov. Cond. index score0.60.77.8-1.0-0.70.40.0-0.0-0.0-0.30.2-0.6-0.2-0.20.3-0.4-2.8
Pavlov. Cond. latency score0.60.87.0-1.5-1.10.00.40.40.40.1-0.2-0.20.20.2-0.10.0-2.6
Pavlov. Cond. lever contacts0.40.54.7-1.0-0.60.20.10.00.1-0.20.1-0.5-0.1-0.10.1-0.2-2.2
Pavlov. Cond. magazine entry number0.81.05.80.0-0.2-1.20.60.70.71.0-0.81.20.80.7-0.90.92.4
Pavlov. Cond. intertrial magazine entries2.73.38.7-0.4-0.9-2.01.61.71.61.9-1.82.21.61.8-1.71.93.0
Pavlov. Cond. lever-magazine prob. diff.0.81.09.5-0.9-0.60.7-0.2-0.2-0.2-0.60.4-0.9-0.4-0.40.5-0.6-3.1
Pavlov. Cond. response bias0.81.06.8-0.20.11.1-0.6-0.6-0.6-0.90.8-1.2-0.8-0.70.9-0.9-2.6
Pavlov. Cond. lever latency4.46.17.6-2.7-2.7-2.42.62.62.62.6-2.62.42.62.5-2.52.50.6
Pavlov. Cond. magazine entry latency1.11.64.62.11.91.1-1.3-1.3-1.3-0.91.1-1.0-1.1-1.01.1-0.71.3
Pavlov. Cond. change in total contacts2.97.29.23.03.02.6-2.8-2.8-2.8-2.72.8-2.6-2.8-2.72.7-2.6-0.7
Pavlov. Cond. index score3.85.99.23.02.92.4-2.6-2.6-2.6-2.32.5-2.3-2.5-2.42.4-2.2-0.0
Pavlov. Cond. latency score3.04.87.02.72.62.1-2.3-2.3-2.3-2.12.2-2.1-2.3-2.22.2-1.9-0.2
Pavlov. Cond. lever contacts4.36.48.12.82.82.5-2.7-2.7-2.7-2.62.6-2.4-2.6-2.62.5-2.4-0.5
Pavlov. Cond. magazine entry number2.43.16.5-2.5-2.3-1.71.91.81.91.5-1.71.61.71.6-1.71.4-0.6
Pavlov. Cond. intertrial magazine entries0.41.03.0-1.7-1.4-0.81.01.01.00.6-0.90.90.90.8-0.80.7-0.3
Pavlov. Cond. lever-magazine prob. diff.4.46.89.63.13.02.6-2.8-2.8-2.8-2.52.7-2.5-2.7-2.62.6-2.4-0.3
Pavlov. Cond. response bias4.15.79.53.13.02.3-2.6-2.5-2.5-2.32.4-2.2-2.4-2.32.3-2.10.3
Time in closed arm before self-admin0.10.21.40.20.20.2-0.0-0.0-0.1-0.4-0.0-0.2-0.00.1-0.1-0.61.2
Time in closed arm after self-admin0.60.71.9-0.4-0.6-0.80.90.90.80.3-0.90.80.80.9-1.00.11.4
Time in open arm before self-admin0.20.32.7-0.3-0.2-0.1-0.1-0.10.00.50.10.1-0.0-0.30.10.6-1.6
Time in open arm after self-admin1.11.33.21.00.90.9-1.2-1.2-1.1-0.41.2-1.2-1.1-1.21.3-0.2-1.8
Bone: periosteal estimation0.92.13.61.91.91.4-1.6-1.5-1.5-1.31.5-1.4-1.3-1.31.3-1.11.1
Bone: periosteal perimeter0.10.31.10.90.70.2-0.5-0.5-0.4-0.30.4-0.2-0.4-0.30.30.01.1
Bone: post-yield work0.00.10.20.4-0.0-0.20.20.30.20.2-0.20.20.20.4-0.20.30.4
Progressive ratio test 1 active lever presses0.10.30.70.80.70.4-0.6-0.6-0.6-0.10.6-0.3-0.5-0.60.4-0.40.2
Progressive ratio test 1 breakpoint0.20.40.80.90.80.5-0.7-0.7-0.7-0.20.7-0.4-0.6-0.70.5-0.50.2
Progressive ratio test 1 inactive lever presses0.20.63.50.50.1-0.70.50.50.40.9-0.71.00.50.6-0.60.81.9
Progressive ratio test 2 active lever presses0.10.10.50.70.50.0-0.4-0.4-0.30.20.20.1-0.2-0.40.20.00.2
Progressive ratio test 2 breakpoint0.10.10.60.80.5-0.0-0.4-0.4-0.30.30.20.1-0.2-0.40.20.00.2
Progressive ratio test 2 inactive lever presses0.20.53.41.31.00.2-0.3-0.3-0.40.10.10.4-0.3-0.30.20.21.9
Incentive Sensitization - Responses0.10.20.60.30.0-0.50.20.20.20.5-0.40.80.30.2-0.30.50.6
Incentive Sensitization - Breakpoint0.10.10.50.50.2-0.50.10.10.10.5-0.30.70.20.1-0.20.50.5
Sum of active levers in priming session hrs 5-60.70.60.9-0.5-0.6-1.00.90.90.80.7-0.90.90.80.9-0.80.50.6
Progressive ratio1.23.44.4-1.0-1.5-2.02.02.01.71.6-2.12.01.72.0-1.91.92.1
Food seeking constrained by brief footshock1.62.13.1-1.6-1.7-1.81.31.31.31.6-1.31.31.41.3-1.31.6-1.0
Seeking ratio, punishment vs. effort0.92.06.70.70.91.2-1.5-1.5-1.3-0.91.6-1.4-1.2-1.51.4-1.2-2.6
Retroperitoneal fat weight22.098.7118.310.610.910.6-10.2-10.2-10.3-10.710.1-10.0-10.2-10.09.9-10.0-1.5
Reaction time number correct0.72.56.1-1.4-1.3-1.21.61.61.60.9-1.61.61.41.6-1.61.62.5
Reaction time mean minus median0.32.14.52.11.81.2-1.5-1.5-1.6-1.11.4-1.3-1.5-1.31.5-1.0-0.8
Reaction time mean minus median AUC0.31.83.71.91.71.1-1.4-1.4-1.5-1.11.3-1.2-1.4-1.21.3-0.8-0.3
Reaction time num false alarms1.62.84.4-2.1-1.8-1.61.61.61.81.6-1.61.51.81.6-1.91.61.2
Reaction time num false alarms AUC1.02.44.0-2.0-1.6-1.51.41.41.61.5-1.51.41.71.5-1.71.40.9
Reaction time trials correct on left0.72.56.1-1.4-1.3-1.21.61.61.60.9-1.61.61.41.6-1.61.62.5
Reaction time trials on left0.72.46.4-1.4-1.3-1.11.61.51.50.9-1.51.61.41.6-1.61.62.5
Reaction time mean2.14.77.72.82.62.0-2.3-2.3-2.4-2.12.2-1.9-2.3-2.12.2-2.0-0.2
Reaction time mean AUC1.64.05.82.42.41.9-2.1-2.1-2.2-2.02.0-1.8-2.1-2.02.0-1.9-0.1
Median of all reaction times2.74.26.22.52.41.9-2.2-2.2-2.2-2.12.1-1.8-2.1-2.12.0-2.00.0
Reaction time omissions0.40.61.61.31.00.8-0.6-0.7-0.8-1.00.7-0.5-0.8-0.50.8-0.60.5
Reaction time false alarm rate0.40.61.2-1.1-0.9-0.90.70.70.81.0-0.70.70.90.7-0.90.6-0.2
Reaction time premature initiation rate0.10.21.2-0.0-0.1-0.60.10.10.20.5-0.20.40.30.1-0.40.21.1
Reaction time premature initiations0.51.45.6-0.8-0.8-1.21.01.01.11.0-1.11.21.11.0-1.31.12.4
Std. dev. reaction times1.03.25.92.42.21.6-1.9-1.9-1.9-1.51.8-1.7-1.9-1.71.8-1.5-0.9
Reaction time trials completed0.72.46.4-1.4-1.3-1.11.61.51.50.9-1.51.61.41.6-1.61.62.5
Reaction time trials AUC0.82.68.5-1.3-1.3-1.21.61.61.60.9-1.61.71.51.6-1.61.62.9
Run reversals in cocaine runway, females2.42.73.31.61.71.7-1.8-1.7-1.7-1.81.8-1.6-1.8-1.81.8-1.5-0.5
Run reversals in cocaine runway, males2.83.15.41.41.41.6-2.0-2.0-1.8-1.11.9-1.9-1.5-2.01.7-1.4-2.3
Latency to leave start box in cocaine runway0.70.94.1-0.7-0.6-0.51.11.00.90.1-1.00.80.81.2-0.80.42.0
Latency to leave start box in cocaine runway, F0.30.44.40.10.20.30.20.10.1-0.6-0.20.10.10.3-0.1-0.22.1
Latency to leave start box in cocaine runway, M2.01.92.9-1.3-1.4-1.31.61.61.51.1-1.61.41.41.7-1.31.01.1
Std. dev. time between licks in bursts0.40.81.3-1.1-1.0-0.90.90.90.90.9-0.80.70.90.8-0.81.0-0.1
Total sessions with >9 infusions0.20.20.90.90.60.0-0.6-0.5-0.50.50.4-0.1-0.3-0.50.40.2-0.3
Short access day 1 total inactive lever presses0.71.35.8-0.2-0.5-1.01.01.11.01.0-1.21.21.11.1-1.21.02.4
Short access day 10 total inactive lever presses0.11.08.10.30.1-0.30.80.80.60.2-0.90.80.70.9-0.70.52.8
Short access day 1 total infusions0.71.43.4-0.7-1.0-1.41.01.01.11.9-1.11.21.21.0-1.11.60.7
Short access day 10 total infusions0.10.10.60.50.40.1-0.2-0.2-0.20.20.10.1-0.1-0.10.10.10.8
Short access total infusions0.10.10.60.80.50.0-0.4-0.4-0.30.50.20.0-0.2-0.30.20.20.1
Short access day 1 locomotion0.00.10.40.20.1-0.1-0.2-0.2-0.00.60.10.10.0-0.20.00.4-0.3
Short access day 10 total locomotion0.20.61.4-0.7-0.7-0.80.70.60.81.2-0.70.90.90.6-0.81.00.5
Short access total locomotion0.10.20.9-0.6-0.5-0.40.0-0.00.31.0-0.10.30.4-0.1-0.30.6-0.7
One hour access (0.3 mA shock)0.70.92.00.1-0.5-1.20.90.90.71.4-1.01.30.81.0-0.71.10.1
Compulsive drug intake2.13.14.6-1.4-1.8-1.92.12.11.71.8-2.11.91.72.1-1.51.4-0.4
One hour access (shock baseline)0.20.51.11.00.90.6-1.0-0.9-0.8-0.20.8-0.6-0.6-0.90.6-0.3-0.1
Social response proportion4.05.16.82.12.52.5-2.2-2.2-2.3-2.62.2-2.3-2.4-2.12.4-2.4-0.8
Social responses0.60.71.10.40.81.0-1.0-1.0-0.8-1.11.0-1.0-0.8-0.90.7-0.90.2
Social time1.52.43.40.91.41.8-1.7-1.7-1.5-1.71.7-1.8-1.5-1.81.5-1.5-0.7
Soleus weight0.00.10.70.20.30.2-0.0-0.1-0.00.00.1-0.30.00.10.1-0.10.8
Bone: stiffness0.10.10.20.50.40.4-0.4-0.4-0.3-0.30.4-0.5-0.2-0.40.2-0.00.4
Tibialis anterior weight0.62.13.41.81.71.6-1.4-1.4-1.5-1.31.4-1.6-1.4-1.31.5-1.3-0.5
Time to tail flick, vehicle, before self-admin1.01.22.61.61.41.2-0.7-0.7-0.9-1.50.7-0.7-1.0-0.50.7-1.51.6
Time to tail flick, vehicle, after self-admin0.00.10.4-0.00.20.3-0.2-0.1-0.1-0.30.1-0.60.0-0.2-0.1-0.60.5
Time to tail flick, test, before self-admin0.30.30.90.1-0.4-0.80.40.40.41.0-0.60.40.60.4-0.50.5-0.9
Time to tail flick, test, after self-admin1.31.35.70.0-0.4-1.10.91.00.91.1-1.11.21.01.1-1.21.12.4
Delta time to tail flick, vehicle, before/after SA0.60.61.2-1.1-0.9-0.90.60.70.81.1-0.70.50.90.6-0.80.80.0
Delta time to tail flick, test, before/after SA0.30.44.7-0.1-0.0-0.10.30.30.3-0.0-0.30.50.20.4-0.40.42.2
Tibia length2.77.49.02.83.02.8-2.9-2.9-2.8-2.82.8-2.8-2.7-2.82.6-2.8-0.7
Ambulatory time before self-admin0.31.11.80.70.91.0-1.2-1.2-1.1-0.81.2-1.3-1.1-1.21.0-0.7-0.8
Ambulatory time after self-admin0.10.20.8-0.8-0.7-0.30.20.10.20.3-0.10.10.20.1-0.10.6-0.9
Bone: tissue strength0.70.81.00.90.90.8-0.9-1.0-0.9-0.60.9-0.9-0.9-1.01.0-0.7-0.8
Total heroin consumption0.30.41.70.1-0.1-0.60.50.60.50.5-0.60.50.50.7-0.50.41.3
Bone: trabecular number0.10.10.5-0.7-0.5-0.20.30.30.30.2-0.20.20.30.3-0.20.3-0.5
Bone: trabecular spacing1.42.03.21.81.61.4-1.5-1.5-1.5-1.21.4-1.5-1.4-1.51.4-1.2-0.3
Bone: trabecular thickness0.00.10.4-0.5-0.4-0.00.10.20.2-0.1-0.10.00.10.1-0.1-0.2-0.6
Bone: trabecular tissue density0.50.81.50.50.60.7-1.0-1.0-1.0-0.91.1-0.9-0.9-1.11.0-0.9-1.2
Water consumed over 24 hours0.10.21.90.40.4-0.2-0.0-0.00.00.2-0.10.30.10.1-0.30.21.4
Number of responses in last shaping day1.21.52.6-0.5-0.8-1.41.21.21.11.5-1.31.61.11.2-1.21.31.4