Hub : Genes

Ccdc38

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Liver mRNA stability Ccdc38 0.38 0.1 0.0e+00 0.34 0.35 0.35 0.36 2.5e-39 1.1e-40 6.5e-40 6.1e-41
2 Liver gene expression Ccdc38 0.27 0.07 0.0e+00 0.28 0.29 0.29 0.29 2.1e-31 5.0e-32 5.0e-32 1.6e-32
3 Liver intron excision ratio chr7_29943159_29944416 0.06 0.03 2.9e-05 0.01 0.02 0.02 0.02 2.0e-02 1.3e-03 3.1e-03 1.3e-03
4 Liver isoform ratio XM_063264413.1 0.08 0.04 9.3e-12 0.07 0.08 0.07 0.07 2.7e-08 1.8e-09 3.7e-08 1.4e-08
5 Adipose gene expression Ccdc38 0.04 0.03 5.6e-03 -0 0.01 0.01 -0 8.4e-01 1.2e-02 6.1e-02 7.2e-01
6 Brain gene expression Ccdc38 0.15 0.06 2.2e-10 0.09 0.11 0.1 0.1 1.7e-08 4.0e-10 1.4e-09 2.0e-09
7 NAcc gene expression Ccdc38 0.1 0.04 1.5e-13 0.06 0.1 0.09 0.09 5.0e-10 9.1e-15 5.8e-14 3.0e-13
8 LHb gene expression Ccdc38 0.33 0.14 1.9e-04 0.11 0.08 0.06 0.13 1.8e-03 6.7e-03 1.9e-02 6.3e-04
9 PL gene expression Ccdc38 0.07 0.03 1.5e-06 0.05 0.05 0.03 0.04 2.0e-06 8.6e-06 1.4e-04 8.6e-05

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9
Bone: apparent density0.61.01.9-0.4-0.70.6-0.91.41.31.21.01.0
Area under the delay curve0.30.31.50.10.00.6-0.3-0.00.40.91.20.2
BMI with tail1.13.78.42.92.50.51.12.02.62.50.20.8
BMI without tail3.29.819.83.52.92.50.93.44.44.42.32.3
Body weight5.423.853.37.36.73.23.94.75.85.51.91.4
Weight adjusted by age1.01.53.11.51.4-0.71.8-0.6-0.7-0.8-1.6-1.4
Bone surface0.20.31.00.1-0.10.4-0.30.81.00.90.40.3
Bone volume0.50.82.40.3-0.00.5-0.41.31.61.40.60.9
Breakpoint value in progressive ratio session0.40.51.4-0.5-0.4-0.7-0.2-1.0-0.3-0.7-1.2-0.4
Number of licking bursts0.10.21.0-0.1-0.3-0.0-0.40.50.20.2-0.21.0
Context. condit. distance diff. score1.11.33.01.31.5-0.61.7-0.6-0.6-0.8-1.2-1.3
Locomotion velocity, session 10.40.41.0-0.3-0.2-0.60.1-1.0-1.0-0.9-0.5-0.4
Locomotion distance, session 10.40.51.10.30.4-1.10.6-0.7-0.8-0.7-0.6-0.5
Locomotion velocity, session 20.30.30.90.1-0.10.4-0.50.40.60.90.40.8
Locomotion distance, session 20.30.41.60.70.6-1.30.00.50.20.6-0.10.3
Locomotion velocity, session 31.01.12.11.41.5-0.71.4-0.6-0.3-0.6-1.3-0.9
Locomotion distance, session 30.70.82.01.41.4-0.61.30.1-0.1-0.2-0.4-0.8
Stereotopy head waving bouts, day 30.81.03.0-1.7-1.6-0.4-1.40.0-0.4-0.30.70.4
Stereotopy head waving duration, day 30.30.31.1-1.1-0.9-0.0-0.9-0.1-0.1-0.00.50.3
Locomotion velocity, session 70.80.93.21.71.8-0.41.3-0.4-0.2-0.1-0.6-0.0
Locomotion distance, session 70.30.41.10.91.0-0.30.9-0.4-0.4-0.2-0.6-0.5
Stereotopy head waving bouts, day 70.50.52.0-0.2-0.11.1-0.40.40.70.70.21.4
Stereotopy head waving duration, day 70.50.61.7-0.3-0.31.2-0.60.51.00.80.21.3
Locomotion velocity, session 80.60.72.31.51.4-0.21.0-0.4-0.10.3-0.5-0.7
Locomotion distance, session 82.43.58.12.82.8-1.92.5-0.4-0.4-0.3-1.7-1.6
Degree of sensitization distance0.20.20.5-0.7-0.70.4-0.6-0.3-0.10.2-0.00.2
Degree of sensitization stereotypy0.60.62.6-0.2-0.21.2-0.50.30.90.7-0.01.6
Conditioned locomotion0.30.30.90.10.20.90.20.90.40.00.80.7
Cocaine response after cond. corrected1.41.73.3-0.6-0.71.8-1.01.41.31.71.61.0
Cocaine response after cond. not corrected0.50.61.3-0.4-0.51.1-0.60.60.81.10.90.2
Cocaine response before conditioning1.92.35.10.30.3-1.80.9-2.3-1.6-1.7-1.7-1.8
Saline control response0.10.20.60.40.20.2-0.1-0.10.40.80.20.7
Bone: connectivity density0.50.81.6-1.0-1.11.2-0.90.90.70.80.90.4
Bone: cortical apparent density0.91.23.61.51.6-0.31.9-0.1-0.6-1.0-0.7-0.8
Bone: cortical area0.60.82.00.90.81.00.91.31.40.8-0.20.0
Bone: cortical porosity1.61.74.0-0.1-0.21.3-1.11.12.01.91.41.1
Bone: cortical porosity1.21.33.1-0.2-0.20.9-1.01.01.81.61.21.1
Bone: cortical thickness0.61.02.40.50.51.40.61.51.50.90.4-0.1
Bone: cortical thickness1.11.33.9-0.7-0.72.0-0.61.51.30.90.80.8
Bone: cortical tissue density1.01.43.91.61.7-0.42.0-0.1-0.7-1.0-0.8-0.9
Condit. Reinf. active minus inactive responses2.12.45.8-0.6-0.5-2.0-0.1-2.4-1.8-1.8-1.9-0.9
Condit. Reinf. active-inactive response ratio1.01.12.2-1.1-1.2-1.3-0.9-1.5-1.0-0.9-0.8-0.2
Condit. Reinf. active responses1.92.45.3-1.4-1.3-2.0-1.1-2.3-1.6-1.4-1.6-0.3
Condit. Reinf. inactive responses0.50.61.5-1.2-1.1-0.6-1.2-0.7-0.5-0.3-0.40.5
Incentive salience index mean1.72.16.0-0.0-0.1-2.4-0.1-2.1-1.5-1.3-2.0-0.9
Condit. Reinf. lever presses0.60.94.10.70.6-2.00.2-0.9-0.6-0.3-1.4-0.4
Condit. Reinf. active minus inactive responses0.10.10.50.30.2-0.10.0-0.70.10.1-0.10.3
Condit. Reinf. active-inactive response ratio0.10.10.40.10.0-0.0-0.2-0.40.50.70.10.2
Condit. Reinf. active responses0.10.20.40.40.3-0.60.3-0.6-0.3-0.4-0.40.2
Condit. Reinf. inactive responses0.30.41.60.10.1-0.40.6-0.5-1.0-1.3-0.3-0.4
Condit. Reinf. lever presses0.91.24.70.70.51.4-0.00.71.21.00.82.2
Condit. Reinf. lever reinforcers received0.30.40.70.70.6-0.70.7-0.9-0.4-0.6-0.70.0
Conditioned reinforcement - actives0.10.21.0-0.1-0.2-1.0-0.6-0.4-0.20.00.00.1
Conditioned reinforcement - inactives0.30.40.8-0.9-0.80.7-0.8-0.10.00.20.60.7
Conditioned locomotion0.20.20.60.30.3-0.50.3-0.8-0.3-0.3-0.7-0.5
Patch foraging indifference point 0 sec0.20.42.40.10.11.6-0.20.40.50.30.50.8
Patch foraging indifference point AUC0.40.61.50.40.31.2-0.20.90.90.90.70.6
Delay disc. indifference point, 0s delay0.30.41.1-0.2-0.30.1-0.9-0.40.40.91.00.4
Delay disc. indifference point, 16s delay0.30.30.80.1-0.0-0.2-0.50.60.70.90.60.5
Delay disc. indifference point, 2s delay1.01.12.11.11.3-0.51.2-1.5-0.9-0.4-0.4-1.4
Delay disc. indifference point, 24s delay0.80.92.71.71.6-0.61.2-0.5-0.00.1-0.4-0.7
Delay disc. indifference point, 4s delay0.60.72.4-0.5-0.41.4-0.60.20.40.81.50.5
Delay disc. indifference point, 8s delay1.31.54.8-0.2-0.31.4-0.90.91.21.62.21.1
Indifference point function ln k0.20.30.90.20.3-0.50.5-1.0-0.7-0.7-0.3-0.5
Indifference point function log k0.20.30.90.20.3-0.50.5-1.0-0.7-0.7-0.3-0.5
Patch foraging total patch changes 0 sec0.30.52.70.20.31.6-0.10.60.60.40.50.8
Patch foraging total patch changes 12 sec1.62.15.21.00.82.3-0.11.61.71.71.31.3
Patch foraging total patch changes 18 sec0.30.52.00.20.21.4-0.40.20.60.60.60.9
Patch foraging total patch changes 24 sec0.61.02.50.80.81.6-0.10.71.21.30.91.0
Patch foraging total patch changes 6 sec0.20.30.90.0-0.01.0-0.70.10.50.50.40.9
Patch foraging time to switch 0 sec0.30.71.3-1.1-1.10.2-0.81.10.60.30.80.8
Patch foraging water rate 0 sec1.02.05.72.42.4-1.21.7-0.8-0.5-0.3-0.9-1.0
Patch foraging water rate 12 sec0.51.03.01.41.20.10.10.61.31.70.50.9
Patch foraging water rate 18 sec0.30.52.40.0-0.0-1.6-0.2-0.4-0.4-0.2-1.10.2
Patch foraging water rate 24 sec2.13.07.62.72.8-1.42.4-0.6-0.5-0.5-1.1-1.4
Patch foraging water rate 6 sec2.43.512.53.53.3-1.02.20.60.70.7-0.80.2
Seeking ratio, delayed vs. immediate footshock1.62.03.3-0.8-0.81.4-1.31.51.51.61.81.6
Distance traveled before self-admin0.70.92.20.80.8-0.61.50.0-0.8-1.0-1.3-1.2
Distance traveled after self-admin0.30.31.20.30.3-0.90.60.2-0.3-0.3-1.1-0.5
Extensor digitorum longus weight0.41.85.0-0.3-0.60.4-1.21.92.21.71.30.8
Bone: elastic displacement0.80.93.3-1.8-1.60.4-1.1-0.2-0.4-0.50.6-0.5
Bone: elastic work0.60.82.7-1.6-1.50.8-1.00.20.2-0.10.5-0.3
Bone: endosteal estimation0.20.41.5-0.5-0.7-0.8-0.70.50.10.1-0.41.2
Bone: endosteal perimeter0.30.61.81.31.3-0.31.10.70.30.1-0.4-0.1
Epididymis fat weight0.93.18.83.03.0-0.42.7-0.30.10.2-1.4-0.7
Delta time in closed arm before/after self-admin0.20.20.5-0.6-0.4-0.70.00.2-0.1-0.2-0.4-0.1
Delta time in open arm before/after self-admin1.71.73.9-0.4-0.61.9-1.30.51.11.42.01.4
Diff in mean of infusions in LGA sessions0.20.30.6-0.8-0.50.2-0.80.00.50.20.20.7
Delay discount exponential model param0.30.41.5-0.3-0.3-0.70.2-0.0-0.4-0.9-1.2-0.2
Extinction: sum of active levers before priming0.20.20.8-0.9-0.7-0.5-0.6-0.4-0.00.2-0.30.3
Active lever presses in extinction session 60.30.30.60.80.8-0.60.20.10.50.6-0.20.3
Bone: final force0.50.81.9-0.4-0.50.7-0.51.31.40.9-0.11.3
Bone: final moment0.50.82.0-0.5-0.60.7-0.61.31.40.9-0.11.2
Food consumed during 24 hour testing period0.10.10.30.50.50.60.4-0.4-0.30.20.20.1
Glucose0.10.10.3-0.0-0.1-0.5-0.50.10.10.3-0.10.4
Heart weight0.91.33.81.91.60.00.70.61.61.4-0.7-0.0
Delay discount hyperbolic model param0.30.31.3-0.4-0.4-0.7-0.10.1-0.3-0.8-1.1-0.1
Intermittent access intake day 1-15 change0.20.50.70.40.6-0.80.6-0.8-0.7-0.7-0.9-0.7
Intermittent access intake escalation0.20.40.60.40.6-0.70.7-0.8-0.6-0.7-0.8-0.7
Intermittent access intake escalation 20.50.61.00.60.7-1.00.9-0.7-0.7-0.8-0.8-0.7
Intermitt. access day 1 inactive lever presses1.04.010.1-3.2-3.11.4-2.8-0.10.00.51.81.7
Intermitt. access day 15 inactive lever presses0.40.72.4-0.3-0.0-0.20.3-1.5-1.1-0.7-1.2-0.9
Intermitt. access escalation Index0.20.30.70.10.2-0.10.6-0.5-0.6-0.6-0.5-0.8
Intermittent access day 1 total infusions0.10.20.60.00.0-0.80.1-0.6-0.50.20.1-0.4
Intermittent access day 15 total infusions0.40.61.30.60.7-1.10.7-0.9-0.9-0.2-0.6-0.8
Intermittent access terminal intake (last 3 days)0.81.03.20.70.8-1.80.8-1.1-1.1-0.4-0.9-1.0
Intermittent access total infusions0.70.83.10.40.4-1.80.3-1.3-1.1-0.1-0.7-0.8
Intermittent access day 1 locomotion0.40.51.8-0.3-0.21.0-0.30.70.41.01.30.5
Intermittent access day 15 total locomotion0.30.61.80.50.6-0.60.5-1.3-1.0-0.6-0.6-1.0
Intermittent access total locomotion0.10.10.20.20.3-0.5-0.0-0.5-0.30.30.2-0.1
Intermittent access standard deviation0.30.62.9-0.5-0.5-1.7-0.2-0.1-1.1-0.6-0.2-0.4
Left kidney weight1.88.424.95.04.70.63.61.72.51.8-1.4-0.8
Right kidney weight1.36.118.24.34.00.52.81.42.41.8-1.3-0.2
Cocaine induced anxiety0.10.10.3-0.1-0.0-0.00.3-0.3-0.6-0.5-0.4-0.6
Post-drug Anxiety0.50.51.00.10.2-0.70.7-0.4-0.9-1.0-0.8-1.0
Baseline Anxiety0.30.30.60.50.6-0.50.8-0.3-0.2-0.5-0.7-0.6
Tail length4.517.537.16.15.73.93.93.64.54.32.21.1
Length with tail5.222.556.17.57.13.45.03.94.84.41.40.5
Length without tail2.68.424.65.04.81.53.61.82.22.10.1-0.5
Times rat made contact with spout0.30.31.3-0.0-0.3-1.1-0.7-0.7-0.10.60.2-0.1
Lifetime Intake0.70.92.90.70.7-1.70.5-1.1-1.0-0.1-0.8-0.9
Liver weight, left1.42.45.01.21.11.70.72.22.02.01.31.1
Liver weight, right1.73.05.91.71.51.20.82.42.32.31.51.1
Locomotor activity2.13.310.03.23.10.71.90.71.91.3-0.80.2
Locomotor testing distance1.01.85.82.42.4-0.21.6-0.40.60.2-1.3-0.2
Locomotor testing rearing0.20.30.70.60.80.20.9-0.5-0.0-0.6-0.6-0.5
Locomotion in novel chamber1.72.23.11.81.7-1.51.5-1.7-1.0-0.8-1.5-1.6
Locomotion in novel chamber post-restriction0.20.30.8-0.6-0.50.4-0.40.90.40.70.30.4
Fecal boli incidents, locomotor time 12.02.96.40.30.11.7-0.82.52.12.02.21.7
Change in fecal boli incidents, locomotor task3.73.77.5-0.6-0.4-2.10.5-2.7-2.4-2.3-2.2-2.0
Time >=10cm from walls, locomotor time 10.10.10.4-0.00.10.00.1-0.6-0.3-0.6-0.3-0.2
Bouts of movement, locomotor time 10.70.71.3-0.5-0.70.0-0.91.20.70.81.11.2
Total resting periods, locomotor time 10.30.40.6-0.6-0.7-0.2-0.80.60.30.40.70.8
Rest time, locomotor task time 10.20.30.8-0.8-0.9-0.0-0.80.10.10.10.40.5
Distance moved, locomotor task time 10.40.61.30.50.6-1.10.6-1.1-0.8-0.6-0.6-1.0
Vertical activity count, locomotor time 10.81.84.31.82.1-1.41.8-0.8-0.6-0.6-0.9-1.3
Time >=10cm from walls, locomotor time 20.30.52.5-0.1-0.2-0.8-0.3-1.6-0.7-0.5-0.7-0.2
Bouts of movement, locomotor time 20.10.10.30.50.50.40.60.20.2-0.00.3-0.3
Total resting periods, locomotor time 20.10.10.20.50.50.10.5-0.00.1-0.20.3-0.4
Rest time, locomotor task time 20.20.20.6-0.6-0.7-0.6-0.6-0.1-0.1-0.5-0.3-0.0
Distance moved, locomotor task time 20.10.10.40.30.30.2-0.00.20.30.60.20.3
Vertical activity count, locomotor time 21.72.34.91.61.60.60.01.52.02.21.31.6
Light reinforcement 10.61.54.11.71.6-0.21.7-0.5-0.4-0.5-2.0-0.2
Light reinforcement 20.30.41.1-0.9-1.10.7-0.90.30.20.20.00.6
Bone: marrow area0.20.41.6-0.5-0.6-0.8-0.60.50.10.2-0.41.3
Bone: maximum diameter0.40.82.21.51.4-0.11.20.70.70.3-0.70.1
Bone: maximum force0.30.51.2-0.4-0.50.8-0.20.81.10.6-0.40.9
Bone: maximum moment0.30.51.2-0.5-0.60.7-0.30.71.10.6-0.40.8
Mean time between licks in bursts0.10.31.00.80.6-1.00.4-0.6-0.1-0.2-0.1-0.5
Mean num. licks in bursts0.30.51.9-0.3-0.3-1.1-0.3-1.4-0.7-0.20.2-0.9
Cd content in liver0.70.82.3-0.1-0.40.3-0.81.51.21.10.80.8
Co content in liver1.11.22.10.60.8-0.91.3-0.8-1.3-1.4-0.9-1.5
Cu content in liver2.83.36.6-0.3-0.32.6-0.82.41.91.92.22.2
Fe content in liver0.30.40.90.50.60.3-0.10.60.90.90.30.7
K content in liver2.52.45.0-0.5-0.51.8-1.01.91.41.32.12.2
Mg content in liver0.40.51.4-0.7-0.60.7-0.60.30.10.10.91.2
Mn content in liver0.10.10.20.20.3-0.30.10.30.1-0.3-0.20.5
Na content in liver1.11.13.20.20.21.8-0.20.51.01.11.41.5
Rb content in liver1.92.24.7-1.5-1.51.7-1.61.31.01.32.21.1
Se content in liver0.30.30.70.50.7-0.50.5-0.7-0.4-0.5-0.80.5
Sr content in liver0.10.10.5-0.1-0.00.7-0.0-0.20.10.4-0.4-0.5
Zn content in liver1.21.34.62.22.10.11.40.40.30.6-0.2-0.2
Bone: minimum diameter1.12.06.32.52.3-0.11.90.81.10.8-0.8-0.3
Time in familiar zone, hab. session 10.10.10.40.60.5-0.10.30.20.20.2-0.4-0.3
Time in novel zone, hab. session 10.60.61.9-1.4-1.30.3-1.0-0.2-0.2-0.20.70.4
Total zone transitions, hab. session 11.82.55.82.42.2-2.21.6-1.0-0.1-0.3-1.5-0.9
Total locomotion distance, hab. session 13.14.410.22.62.5-3.21.9-2.0-0.9-0.9-2.4-1.4
Locomotion velocity, hab. session 14.66.515.33.02.9-3.92.3-2.5-1.3-1.3-2.9-1.8
Time in familiar zone, hab. session 20.10.10.30.20.1-0.1-0.00.50.60.5-0.30.1
Time in novel zone, hab. session 20.20.20.4-0.6-0.60.3-0.4-0.6-0.5-0.40.5-0.1
Total zone transitions, hab. session 21.62.05.90.91.0-2.41.1-1.4-1.1-1.3-1.7-1.2
Total locomotion distance, hab. session 22.12.810.40.70.8-3.20.8-1.9-1.4-1.5-1.7-1.3
Locomotion velocity, hab. session 22.73.612.21.01.1-3.51.2-2.0-1.7-1.8-2.0-1.6
Novel to familiar place preference ratio0.30.30.90.50.71.00.5-0.9-0.10.30.3-0.1
Novelty place preference0.30.31.20.30.51.10.4-1.0-0.10.30.4-0.1
Time in novel zone, NPP test0.30.41.70.40.51.30.4-0.80.10.50.50.0
Total zone transitions, NPP test0.60.82.11.31.4-0.51.3-0.4-0.0-0.2-0.9-0.6
Total locomotion distance, NPP test1.52.15.11.31.4-2.31.2-1.6-1.0-1.1-1.8-0.8
Locomotion velocity, NPP test1.82.56.51.01.2-2.51.2-1.8-1.4-1.5-2.0-1.0
Intraocular pressure1.31.94.4-2.1-1.9-0.9-0.8-1.4-1.9-1.3-0.6-0.6
Delta distance traveled before/after self-admin0.50.51.0-0.5-0.5-0.1-0.90.60.70.80.51.0
Delta ambulatory time before/after self-admin0.50.61.5-0.8-0.8-0.2-1.20.40.50.70.61.0
Parametrial fat weight0.51.13.91.21.10.40.82.01.30.7-0.10.4
Pavlov. Cond. lever latency0.40.61.40.60.71.20.80.80.50.51.0-0.1
Pavlov. Cond. magazine entry latency1.11.53.60.0-0.0-1.90.4-1.6-1.2-1.3-1.8-0.6
Pavlov. Cond. change in total contacts0.91.03.5-0.7-0.8-1.9-0.7-1.0-1.0-0.9-1.00.2
Pavlov. Cond. index score0.60.82.8-0.3-0.4-1.7-0.4-1.0-0.7-0.7-1.4-0.1
Pavlov. Cond. latency score0.81.03.1-0.4-0.6-1.8-0.5-1.1-0.8-0.7-1.6-0.1
Pavlov. Cond. lever contacts0.30.31.1-0.2-0.3-1.0-0.6-0.5-0.2-0.1-0.90.2
Pavlov. Cond. magazine entry number0.70.92.90.10.11.7-0.30.91.01.01.30.5
Pavlov. Cond. intertrial magazine entries0.00.00.10.10.2-0.10.2-0.2-0.3-0.4-0.1-0.0
Pavlov. Cond. lever-magazine prob. diff.0.50.62.5-0.2-0.4-1.6-0.3-0.8-0.6-0.5-1.2-0.1
Pavlov. Cond. response bias0.70.82.6-0.4-0.5-1.6-0.3-1.1-0.9-0.9-1.3-0.0
Pavlov. Cond. lever latency0.20.31.4-0.5-0.6-0.4-0.50.5-0.1-0.2-0.0-1.2
Pavlov. Cond. magazine entry latency1.21.41.81.01.1-1.41.3-1.3-1.2-1.2-1.3-0.8
Pavlov. Cond. change in total contacts1.11.75.12.22.3-0.81.8-1.1-0.5-0.1-0.3-0.3
Pavlov. Cond. index score0.71.02.21.31.5-0.61.5-1.0-0.7-0.6-0.50.1
Pavlov. Cond. latency score0.70.91.91.21.3-0.71.4-1.1-0.9-0.8-0.5-0.0
Pavlov. Cond. lever contacts0.30.41.90.70.70.20.5-0.50.20.30.11.4
Pavlov. Cond. magazine entry number1.72.13.4-1.6-1.71.6-1.91.21.41.41.40.4
Pavlov. Cond. intertrial magazine entries0.30.51.40.40.31.20.20.91.10.60.3-0.2
Pavlov. Cond. lever-magazine prob. diff.0.81.02.31.31.4-0.71.5-1.1-0.8-0.7-0.60.0
Pavlov. Cond. response bias0.40.61.41.21.2-0.31.0-0.6-0.10.1-0.30.9
Time in closed arm before self-admin0.81.01.51.21.1-0.61.2-1.0-0.3-0.7-1.2-1.1
Time in closed arm after self-admin0.20.20.60.70.5-0.40.60.20.30.2-0.8-0.1
Time in open arm before self-admin0.40.41.3-0.4-0.3-1.1-0.1-0.6-0.8-0.7-0.7-0.5
Time in open arm after self-admin0.80.92.3-0.7-0.81.3-1.20.10.40.71.50.9
Bone: periosteal estimation0.10.30.60.60.5-0.20.60.80.50.3-0.80.4
Bone: periosteal perimeter0.30.51.11.11.00.10.90.70.80.4-0.4-0.3
Bone: post-yield work0.20.30.7-0.6-0.70.5-0.40.20.60.5-0.70.8
Progressive ratio test 1 active lever presses0.50.72.21.51.4-0.60.80.1-0.00.90.2-0.2
Progressive ratio test 1 breakpoint0.50.62.11.41.4-0.60.70.0-0.10.80.2-0.3
Progressive ratio test 1 inactive lever presses0.20.30.8-0.9-0.70.5-0.5-0.1-0.3-0.00.80.3
Progressive ratio test 2 active lever presses0.40.41.60.60.6-1.30.4-0.7-0.50.0-0.7-0.4
Progressive ratio test 2 breakpoint0.50.62.00.60.6-1.40.5-0.9-0.7-0.1-0.8-0.5
Progressive ratio test 2 inactive lever presses0.30.51.40.10.3-1.10.1-1.2-0.7-0.1-0.9-0.4
Incentive Sensitization - Responses0.30.51.50.60.6-1.20.4-0.7-0.3-0.1-1.1-0.4
Incentive Sensitization - Breakpoint0.30.51.40.50.5-1.20.4-0.8-0.4-0.2-1.0-0.4
Sum of active levers in priming session hrs 5-60.20.20.80.10.2-0.1-0.30.40.70.90.30.6
Progressive ratio2.33.56.6-0.2-0.2-1.91.1-2.1-2.3-2.6-2.3-2.2
Food seeking constrained by brief footshock0.20.20.40.50.60.00.00.60.40.70.60.4
Seeking ratio, punishment vs. effort1.52.24.30.40.51.2-0.71.81.82.11.91.7
Retroperitoneal fat weight1.04.212.83.63.60.33.01.01.00.5-0.7-0.5
Reaction time number correct0.10.10.40.50.5-0.20.3-0.6-0.2-0.1-0.2-0.4
Reaction time mean minus median0.10.30.6-0.7-0.7-0.0-0.3-0.8-0.3-0.6-0.1-0.6
Reaction time mean minus median AUC0.20.51.1-0.9-0.8-0.8-0.5-1.1-0.7-0.7-0.4-0.5
Reaction time num false alarms1.11.63.3-1.8-1.71.2-1.60.70.70.61.01.3
Reaction time num false alarms AUC1.21.84.2-2.1-1.91.3-1.80.50.60.50.91.3
Reaction time trials correct on left0.10.10.40.50.5-0.20.3-0.6-0.2-0.1-0.2-0.4
Reaction time trials on left0.10.10.40.50.4-0.20.3-0.6-0.3-0.2-0.2-0.4
Reaction time mean0.20.40.9-0.7-0.6-0.90.0-0.2-0.5-1.0-0.2-0.7
Reaction time mean AUC0.20.20.6-0.8-0.7-0.5-0.1-0.0-0.3-0.70.2-0.5
Median of all reaction times0.20.31.1-0.6-0.5-1.00.00.1-0.5-0.9-0.1-0.4
Reaction time omissions1.01.53.4-1.9-1.7-0.5-0.8-1.2-1.2-1.4-0.4-1.3
Reaction time false alarm rate1.31.84.6-2.1-2.00.9-1.80.60.50.40.71.4
Reaction time premature initiation rate0.40.62.10.70.5-1.40.4-0.2-0.1-0.7-1.4-0.5
Reaction time premature initiations0.30.61.50.90.7-1.10.5-0.4-0.1-0.6-1.2-0.8
Std. dev. reaction times0.30.51.4-1.2-1.1-0.2-0.4-0.5-0.4-0.9-0.2-0.7
Reaction time trials completed0.10.10.40.50.4-0.20.3-0.6-0.3-0.2-0.2-0.4
Reaction time trials AUC0.10.10.30.60.5-0.20.2-0.4-0.2-0.0-0.0-0.3
Run reversals in cocaine runway, females0.80.72.40.90.7-1.11.01.60.3-0.3-0.8-0.4
Run reversals in cocaine runway, males0.50.52.40.20.40.10.4-1.5-0.9-0.5-1.0-0.3
Latency to leave start box in cocaine runway0.30.31.01.01.00.40.8-0.00.30.10.1-0.0
Latency to leave start box in cocaine runway, F0.40.51.4-0.20.1-0.30.4-0.9-1.1-1.2-0.5-0.6
Latency to leave start box in cocaine runway, M2.42.24.91.71.51.50.61.42.22.10.61.0
Std. dev. time between licks in bursts0.20.30.50.70.7-0.40.7-0.7-0.2-0.4-0.3-0.2
Total sessions with >9 infusions0.30.30.90.70.6-0.70.00.60.31.00.30.3
Short access day 1 total inactive lever presses1.11.54.7-2.2-2.00.3-1.50.80.30.60.51.0
Short access day 10 total inactive lever presses0.30.72.4-1.6-1.20.7-0.5-0.6-0.5-0.9-0.10.0
Short access day 1 total infusions0.50.62.8-0.1-0.1-1.70.4-0.1-0.9-0.5-1.0-0.7
Short access day 10 total infusions0.40.51.71.11.00.20.30.20.61.30.50.3
Short access total infusions0.40.51.11.00.9-1.00.7-0.2-0.40.3-0.4-0.6
Short access day 1 locomotion0.40.61.60.0-0.10.6-0.40.91.01.30.70.8
Short access day 10 total locomotion1.12.04.6-2.0-2.10.3-2.10.80.20.41.41.3
Short access total locomotion1.01.22.5-0.5-0.60.9-1.21.01.01.51.61.2
One hour access (0.3 mA shock)3.43.99.02.02.1-3.01.8-1.9-1.6-0.9-2.0-1.9
Compulsive drug intake0.10.10.30.50.60.10.3-0.1-0.10.10.2-0.2
One hour access (shock baseline)0.81.23.60.90.8-1.90.8-1.2-0.8-0.3-1.6-0.9
Social response proportion1.82.04.31.81.5-0.30.52.11.81.80.90.7
Social responses1.41.85.62.42.2-1.31.50.00.50.3-0.7-0.9
Social time0.60.91.9-0.7-0.8-0.3-1.11.41.31.10.40.5
Soleus weight0.31.04.90.50.30.3-0.02.21.41.0-0.20.7
Bone: stiffness1.11.84.70.50.30.9-0.12.12.21.50.71.7
Tibialis anterior weight0.51.73.2-1.6-1.8-0.2-1.61.61.40.81.10.1
Time to tail flick, vehicle, before self-admin0.30.31.21.10.90.10.50.30.20.50.6-0.1
Time to tail flick, vehicle, after self-admin1.72.25.3-1.6-1.90.3-2.31.20.81.11.51.7
Time to tail flick, test, before self-admin0.40.41.10.80.90.50.71.10.50.20.20.1
Time to tail flick, test, after self-admin0.40.41.71.30.9-0.10.70.30.10.1-0.2-0.2
Delta time to tail flick, vehicle, before/after SA2.42.35.3-2.0-2.10.2-2.30.90.60.91.21.7
Delta time to tail flick, test, before/after SA0.10.10.60.30.1-0.10.0-0.8-0.10.1-0.2-0.1
Tibia length3.28.928.55.35.1-0.64.31.01.01.0-1.0-1.6
Ambulatory time before self-admin0.20.30.90.60.50.10.90.7-0.0-0.2-0.6-0.4
Ambulatory time after self-admin0.60.71.71.01.0-0.91.30.3-0.4-0.4-1.0-0.8
Bone: tissue strength0.90.91.8-0.5-0.50.9-0.61.21.30.90.91.2
Total heroin consumption0.70.82.10.20.5-0.40.8-1.4-0.8-0.9-1.5-1.0
Bone: trabecular number0.30.51.4-1.0-1.20.5-0.80.90.50.30.60.3
Bone: trabecular spacing0.81.12.70.70.9-0.41.0-1.6-1.0-0.9-1.1-1.3
Bone: trabecular thickness1.01.23.30.60.31.1-0.01.81.61.30.71.1
Bone: trabecular tissue density0.30.50.90.80.9-0.60.8-0.4-1.0-0.9-0.30.2
Water consumed over 24 hours1.41.84.0-0.1-0.40.9-1.01.61.52.01.81.6
Number of responses in last shaping day0.70.81.9-0.3-0.1-0.70.4-1.4-1.3-0.9-0.9-1.0