Hub : Genes

Hspa12a

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Brain gene expression Hspa12a 0.11 0.06 5.2e-08 0.07 0.09 0.1 0.08 5.5e-07 1.5e-08 1.2e-09 1.1e-07
2 OFC gene expression Hspa12a 0.27 0.15 2.5e-04 0.09 0.18 0.14 0.14 3.9e-03 4.0e-05 4.4e-04 3.6e-04
3 PL mRNA stability Hspa12a 0.06 0.06 5.9e-03 0.03 0.02 0.02 0.01 5.9e-04 2.5e-03 3.1e-03 1.6e-02
4 pVTA mRNA stability Hspa12a 0.33 0.16 1.6e-08 0.1 0.21 0.19 0.2 4.5e-05 1.3e-09 1.1e-08 3.4e-09
5 Adipose gene expression Hspa12a 0.41 0.13 0.0e+00 0.25 0.25 0.26 0.26 2.6e-27 5.5e-28 1.6e-28 3.2e-28
6 OFC mRNA stability Hspa12a 0.21 0.13 2.1e-03 0.1 0.07 0.05 0.04 2.9e-03 1.1e-02 2.3e-02 4.0e-02
7 NAcc gene expression Hspa12a 0.03 0.03 6.3e-04 0.02 0.02 0.01 0.01 3.6e-03 2.6e-03 1.2e-02 7.4e-03
8 Adipose mRNA stability Hspa12a 0.23 0.1 0.0e+00 0.12 0.14 0.16 0.15 5.2e-13 9.4e-16 4.4e-17 1.0e-16
9 Liver gene expression Hspa12a 0.04 0.02 1.1e-04 0.03 0.03 0.02 0.03 2.9e-04 4.0e-04 3.6e-03 5.5e-04

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9
Bone: apparent density2.33.85.62.4-1.71.91.32.2-1.92.12.11.8
Area under the delay curve1.11.23.50.7-1.6-0.61.90.3-0.6-1.3-0.2-1.3
BMI with tail4.514.749.27.0-5.13.74.73.0-3.10.71.70.0
BMI without tail3.26.619.34.4-3.71.23.42.3-2.40.41.5-0.0
Body weight4.820.361.97.9-6.13.95.73.9-3.90.72.3-0.0
Weight adjusted by age1.21.35.42.3-1.21.81.20.3-0.4-0.1-0.1-0.3
Bone surface1.52.74.42.1-1.12.00.71.7-1.51.91.61.7
Bone volume1.93.38.02.8-1.91.91.51.9-1.81.31.51.0
Breakpoint value in progressive ratio session2.02.24.60.0-2.1-1.52.01.7-1.80.31.50.3
Number of licking bursts1.21.43.70.2-0.00.5-0.31.2-1.11.91.51.9
Context. condit. distance diff. score0.50.61.5-0.11.01.2-1.1-0.60.80.5-0.30.3
Locomotion velocity, session 10.10.10.2-0.50.4-0.3-0.4-0.20.40.0-0.10.2
Locomotion distance, session 11.01.22.5-0.71.60.7-1.5-1.31.4-0.3-1.1-0.2
Locomotion velocity, session 22.02.34.9-1.62.20.4-2.2-1.81.9-0.2-1.40.0
Locomotion distance, session 21.01.34.40.71.32.1-1.3-1.11.2-0.0-1.0-0.0
Locomotion velocity, session 30.70.81.6-1.11.30.3-1.2-1.01.0-0.2-0.8-0.2
Locomotion distance, session 31.41.52.6-0.71.61.0-1.5-1.51.5-0.5-1.4-0.7
Stereotopy head waving bouts, day 30.30.31.0-0.80.2-1.0-0.1-0.50.4-0.7-0.5-0.5
Stereotopy head waving duration, day 30.20.21.3-0.90.1-1.1-0.1-0.00.0-0.10.10.1
Locomotion velocity, session 70.50.63.00.50.61.7-0.7-0.20.40.7-0.10.4
Locomotion distance, session 70.81.04.50.71.02.1-1.0-0.80.90.2-0.7-0.0
Stereotopy head waving bouts, day 70.20.20.30.1-0.3-0.30.30.6-0.60.40.60.5
Stereotopy head waving duration, day 70.60.81.90.2-1.2-1.41.30.8-1.0-0.40.6-0.3
Locomotion velocity, session 81.11.33.0-1.11.50.8-1.7-0.20.61.40.31.5
Locomotion distance, session 82.53.68.5-0.62.72.8-2.9-1.21.61.6-0.51.4
Degree of sensitization distance0.70.71.31.1-0.80.70.71.0-0.80.80.90.7
Degree of sensitization stereotypy0.60.61.21.1-1.00.20.90.9-1.00.40.70.3
Conditioned locomotion0.20.20.7-0.4-0.2-0.80.4-0.1-0.1-0.6-0.2-0.7
Cocaine response after cond. corrected4.34.87.5-2.42.7-0.2-2.4-2.72.7-1.4-2.4-1.3
Cocaine response after cond. not corrected3.74.18.0-2.82.5-0.7-2.3-2.32.4-1.0-1.9-0.9
Cocaine response before conditioning1.01.22.3-0.5-0.8-0.90.61.4-1.31.11.51.2
Saline control response0.20.20.50.1-0.00.00.1-0.50.5-0.7-0.6-0.7
Bone: connectivity density1.21.83.41.2-0.81.30.41.6-1.21.81.61.6
Bone: cortical apparent density3.14.16.3-2.12.50.4-2.2-2.52.5-1.4-2.2-1.4
Bone: cortical area3.24.812.93.6-1.73.01.32.0-1.82.01.71.7
Bone: cortical porosity0.80.91.60.5-1.1-1.00.91.2-1.30.71.10.7
Bone: cortical porosity1.51.62.70.9-1.6-0.91.51.6-1.70.71.40.7
Bone: cortical thickness2.13.414.93.0-0.23.9-0.20.8-0.51.80.71.4
Bone: cortical thickness0.91.14.92.2-0.32.10.2-0.20.30.2-0.4-0.1
Bone: cortical tissue density3.34.46.6-2.32.50.2-2.2-2.62.6-1.5-2.2-1.4
Condit. Reinf. active minus inactive responses0.60.61.3-0.60.90.8-1.2-0.10.31.10.31.1
Condit. Reinf. active-inactive response ratio0.30.41.0-1.00.6-0.2-0.70.10.00.70.40.8
Condit. Reinf. active responses1.31.55.41.00.32.3-0.70.6-0.31.80.81.6
Condit. Reinf. inactive responses1.92.27.62.0-0.22.8-0.10.9-0.71.91.01.6
Incentive salience index mean0.70.92.3-0.31.21.5-1.4-0.40.50.9-0.10.9
Condit. Reinf. lever presses0.30.51.90.10.81.4-0.8-0.50.40.3-0.40.2
Condit. Reinf. active minus inactive responses1.82.33.61.6-1.7-0.11.51.9-1.91.01.71.2
Condit. Reinf. active-inactive response ratio1.11.12.41.5-1.20.21.11.2-1.30.61.00.7
Condit. Reinf. active responses2.63.65.62.3-2.20.32.02.4-2.31.32.11.3
Condit. Reinf. inactive responses1.01.21.91.3-1.40.21.31.4-1.30.61.10.5
Condit. Reinf. lever presses1.01.42.71.6-1.30.61.21.4-1.20.81.20.7
Condit. Reinf. lever reinforcers received2.02.84.51.7-1.70.31.52.1-2.01.42.01.5
Conditioned reinforcement - actives2.42.45.3-2.32.2-1.0-2.0-1.61.7-0.5-1.2-0.4
Conditioned reinforcement - inactives0.20.20.5-0.1-0.4-0.70.40.5-0.40.30.60.3
Conditioned locomotion2.02.45.2-2.22.3-0.7-2.1-1.61.8-0.2-1.1-0.1
Patch foraging indifference point 0 sec1.42.35.52.3-1.52.31.21.4-1.21.11.10.9
Patch foraging indifference point AUC0.80.91.70.9-1.30.41.21.2-1.20.41.00.3
Delay disc. indifference point, 0s delay0.40.51.11.00.01.00.0-0.60.5-0.6-0.7-0.7
Delay disc. indifference point, 16s delay0.70.72.10.2-1.2-0.51.40.2-0.4-1.0-0.2-1.0
Delay disc. indifference point, 2s delay1.21.43.9-0.0-0.3-0.70.7-1.00.7-2.0-1.4-2.0
Delay disc. indifference point, 24s delay0.70.72.10.5-1.4-0.31.50.9-0.9-0.20.5-0.1
Delay disc. indifference point, 4s delay0.70.71.70.1-1.1-0.71.3-0.0-0.3-1.2-0.4-1.2
Delay disc. indifference point, 8s delay0.90.92.50.6-1.4-0.81.60.2-0.5-1.1-0.2-1.1
Indifference point function ln k0.30.40.8-0.60.90.4-0.9-0.80.8-0.0-0.70.0
Indifference point function log k0.30.40.8-0.60.90.4-0.9-0.80.8-0.0-0.70.0
Patch foraging total patch changes 0 sec1.83.06.72.6-1.72.51.41.6-1.41.31.31.0
Patch foraging total patch changes 12 sec2.12.74.12.0-1.81.51.51.9-1.71.31.71.0
Patch foraging total patch changes 18 sec2.63.45.51.9-2.30.92.12.3-2.20.91.90.9
Patch foraging total patch changes 24 sec2.32.84.71.8-2.00.61.72.2-2.01.22.01.1
Patch foraging total patch changes 6 sec2.74.05.82.4-2.02.21.72.3-2.01.82.01.4
Patch foraging time to switch 0 sec0.60.93.4-1.30.4-1.9-0.2-0.70.5-1.1-0.6-1.0
Patch foraging water rate 0 sec0.81.34.91.8-0.82.20.60.7-0.50.90.50.6
Patch foraging water rate 12 sec1.42.23.61.9-1.31.41.01.7-1.61.51.51.3
Patch foraging water rate 18 sec0.20.30.60.70.30.8-0.2-0.50.5-0.2-0.6-0.3
Patch foraging water rate 24 sec0.40.51.31.1-0.41.00.5-0.30.3-0.7-0.7-0.9
Patch foraging water rate 6 sec0.20.21.20.7-0.31.10.3-0.10.2-0.3-0.4-0.3
Seeking ratio, delayed vs. immediate footshock1.31.43.5-1.71.9-0.7-1.8-1.11.20.2-0.60.1
Distance traveled before self-admin2.62.85.0-1.11.1-0.4-0.8-2.01.8-2.2-2.2-2.2
Distance traveled after self-admin1.51.72.7-1.11.1-0.5-0.8-1.61.5-1.5-1.6-1.5
Extensor digitorum longus weight1.14.411.93.4-3.00.62.91.9-2.10.01.1-0.4
Bone: elastic displacement0.40.51.30.2-0.3-0.70.5-0.40.2-1.1-0.7-1.2
Bone: elastic work0.70.92.10.90.00.70.1-1.00.7-1.3-1.3-1.4
Bone: endosteal estimation0.40.91.81.4-1.30.21.21.1-1.20.40.80.5
Bone: endosteal perimeter0.81.74.01.8-2.0-0.22.01.1-1.3-0.40.6-0.4
Epididymis fat weight8.920.752.27.2-5.73.95.14.6-4.62.13.41.4
Delta time in closed arm before/after self-admin0.70.71.3-1.01.10.0-1.1-1.01.0-0.1-0.7-0.3
Delta time in open arm before/after self-admin2.52.54.50.2-1.4-1.31.22.1-2.11.32.11.5
Diff in mean of infusions in LGA sessions1.11.22.00.2-1.4-0.91.31.4-1.40.51.30.5
Delay discount exponential model param1.31.44.0-0.61.70.8-2.0-0.30.61.40.31.4
Extinction: sum of active levers before priming1.01.02.10.1-1.4-1.41.50.9-1.1-0.20.70.1
Active lever presses in extinction session 60.60.61.60.7-1.3-0.11.30.8-0.9-0.20.50.0
Bone: final force1.62.68.42.9-0.92.90.61.0-0.91.30.80.9
Bone: final moment1.52.47.82.8-1.12.60.81.1-1.01.20.80.9
Food consumed during 24 hour testing period0.30.30.8-0.40.80.5-0.9-0.20.30.60.10.6
Glucose2.03.17.82.8-2.40.72.31.7-1.80.21.2-0.1
Heart weight1.42.08.83.0-1.22.51.10.5-0.40.40.10.2
Delay discount hyperbolic model param1.21.33.4-0.61.50.8-1.8-0.10.41.50.51.5
Intermittent access intake day 1-15 change0.80.81.9-0.3-1.4-1.31.30.7-0.9-0.60.5-0.5
Intermittent access intake escalation0.40.41.1-0.6-0.4-0.70.5-0.30.2-1.1-0.5-1.0
Intermittent access intake escalation 20.20.20.6-0.4-0.4-0.60.5-0.20.0-0.7-0.3-0.7
Intermitt. access day 1 inactive lever presses2.52.76.20.8-2.5-1.22.41.9-2.00.31.70.2
Intermitt. access day 15 inactive lever presses0.40.41.20.6-1.10.21.00.7-0.7-0.10.5-0.1
Intermitt. access escalation Index0.50.40.7-0.4-0.2-0.90.4-0.70.6-0.8-0.7-0.8
Intermittent access day 1 total infusions0.10.10.4-0.60.2-0.3-0.2-0.20.2-0.3-0.2-0.2
Intermittent access day 15 total infusions0.60.71.7-1.3-0.4-1.10.5-0.30.1-1.2-0.4-1.0
Intermittent access terminal intake (last 3 days)0.30.30.7-0.8-0.5-0.80.60.0-0.1-0.8-0.1-0.7
Intermittent access total infusions0.30.31.0-1.00.0-0.70.1-0.40.2-0.8-0.4-0.7
Intermittent access day 1 locomotion1.41.42.7-1.60.7-0.7-0.4-1.31.2-1.5-1.3-1.4
Intermittent access day 15 total locomotion0.70.82.10.1-1.4-0.51.40.9-1.1-0.30.7-0.4
Intermittent access total locomotion0.70.81.8-1.20.4-0.2-0.3-0.90.7-1.3-1.0-1.3
Intermittent access standard deviation0.80.92.1-0.5-1.1-1.51.01.0-1.10.10.90.3
Left kidney weight1.74.825.63.00.55.1-0.5-1.31.7-0.2-1.7-0.9
Right kidney weight1.54.319.63.5-0.14.40.1-1.11.3-0.4-1.7-1.0
Cocaine induced anxiety1.92.16.3-1.22.50.7-2.5-1.21.50.7-0.60.5
Post-drug Anxiety0.60.61.7-0.21.20.8-1.3-0.30.50.9-0.00.8
Baseline Anxiety2.52.76.01.4-2.5-0.92.41.9-2.10.21.40.4
Tail length0.41.12.00.6-1.4-1.01.41.2-1.40.11.00.1
Length with tail0.72.47.02.6-2.01.31.91.5-1.50.31.00.1
Length without tail1.12.58.72.8-1.22.91.01.0-0.80.90.60.7
Times rat made contact with spout0.00.00.20.3-0.00.5-0.00.0-0.10.10.00.1
Lifetime Intake0.30.41.3-1.10.4-0.7-0.3-0.50.4-0.5-0.5-0.5
Liver weight, left2.13.38.12.3-2.8-0.62.81.8-2.0-0.21.1-0.4
Liver weight, right3.04.911.83.4-3.40.13.41.9-2.2-0.41.1-0.5
Locomotor activity0.00.00.10.1-0.1-0.20.2-0.20.0-0.3-0.2-0.3
Locomotor testing distance0.61.01.7-0.90.7-0.2-0.5-1.31.2-1.1-1.3-1.2
Locomotor testing rearing0.61.02.5-0.6-0.1-1.00.4-0.90.8-1.5-1.1-1.6
Locomotion in novel chamber0.70.81.5-0.50.90.5-0.8-1.11.2-0.7-1.1-0.9
Locomotion in novel chamber post-restriction1.82.13.7-0.31.71.2-1.5-1.81.9-1.0-1.8-1.1
Fecal boli incidents, locomotor time 10.20.20.4-0.4-0.20.60.10.5-0.40.60.60.5
Change in fecal boli incidents, locomotor task0.50.51.40.7-0.11.2-0.10.6-0.40.90.60.7
Time >=10cm from walls, locomotor time 10.30.30.7-0.80.60.1-0.70.10.10.70.30.8
Bouts of movement, locomotor time 10.91.02.1-0.3-1.5-1.21.41.1-1.2-0.10.90.0
Total resting periods, locomotor time 10.50.51.1-0.4-1.1-0.91.00.7-0.8-0.20.6-0.1
Rest time, locomotor task time 11.01.13.10.51.31.8-1.4-0.91.10.3-0.80.1
Distance moved, locomotor task time 10.20.30.9-0.1-0.5-0.90.7-0.0-0.1-0.7-0.2-0.6
Vertical activity count, locomotor time 10.20.20.50.4-0.0-0.10.2-0.50.4-0.7-0.6-0.7
Time >=10cm from walls, locomotor time 20.91.04.10.50.62.0-0.80.20.01.40.41.1
Bouts of movement, locomotor time 21.11.25.5-1.3-0.1-2.30.4-0.50.2-1.3-0.5-1.1
Total resting periods, locomotor time 21.31.45.5-1.3-0.3-2.30.7-0.50.2-1.5-0.6-1.4
Rest time, locomotor task time 20.40.41.0-0.70.1-0.50.0-0.70.5-1.0-0.7-1.0
Distance moved, locomotor task time 20.50.51.61.30.51.0-0.60.10.10.90.20.9
Vertical activity count, locomotor time 20.40.40.90.90.50.9-0.60.2-0.00.90.30.8
Light reinforcement 10.30.52.10.30.81.4-0.9-0.60.6-0.2-0.6-0.1
Light reinforcement 20.50.71.8-0.41.40.6-1.3-0.90.90.0-0.70.1
Bone: marrow area0.51.02.11.5-1.30.21.21.1-1.20.50.90.5
Bone: maximum diameter2.34.27.12.6-2.70.52.42.4-2.51.11.91.0
Bone: maximum force1.22.27.72.4-0.52.80.10.8-0.61.50.71.3
Bone: maximum moment1.12.06.32.3-0.52.50.20.9-0.71.50.81.3
Mean time between licks in bursts1.01.42.5-1.0-0.6-1.50.41.3-1.31.11.61.3
Mean num. licks in bursts1.41.64.3-0.00.1-0.10.2-1.41.2-2.0-1.7-2.1
Cd content in liver2.12.34.6-1.91.70.6-2.00.20.32.00.92.1
Co content in liver1.41.64.3-0.31.72.1-1.8-1.01.30.7-0.70.7
Cu content in liver0.10.20.3-0.00.40.1-0.3-0.50.5-0.4-0.5-0.4
Fe content in liver1.11.33.01.3-0.21.7-0.10.9-0.71.61.11.5
K content in liver0.30.31.1-0.3-0.3-1.00.5-0.1-0.1-0.8-0.2-0.7
Mg content in liver1.01.02.40.3-1.0-1.41.3-0.0-0.3-1.6-0.4-1.5
Mn content in liver0.20.30.70.7-0.40.10.5-0.30.1-0.8-0.5-0.8
Na content in liver1.11.22.91.0-1.5-1.41.70.5-0.7-1.10.0-1.0
Rb content in liver0.70.92.9-0.4-1.0-1.71.20.2-0.5-1.1-0.0-1.0
Se content in liver0.40.51.4-0.10.10.5-0.30.6-0.41.20.91.1
Sr content in liver2.22.15.0-2.21.4-0.9-1.3-1.61.6-1.0-1.3-1.0
Zn content in liver2.83.15.9-0.20.9-0.4-0.5-2.22.0-2.4-2.4-2.4
Bone: minimum diameter1.62.98.42.9-1.72.11.41.6-1.61.11.20.9
Time in familiar zone, hab. session 10.90.91.91.3-0.60.50.8-0.50.4-1.2-0.9-1.4
Time in novel zone, hab. session 11.21.22.6-0.9-0.1-0.8-0.11.2-1.11.41.51.6
Total zone transitions, hab. session 10.50.72.31.5-0.11.50.2-0.40.3-0.5-0.6-0.7
Total locomotion distance, hab. session 10.71.02.70.40.31.2-0.60.8-0.41.61.01.6
Locomotion velocity, hab. session 10.60.82.20.30.41.3-0.70.5-0.31.50.81.4
Time in familiar zone, hab. session 21.21.32.30.2-1.2-0.91.01.5-1.50.81.50.9
Time in novel zone, hab. session 20.90.91.7-0.21.00.8-0.9-1.31.3-0.7-1.3-0.8
Total zone transitions, hab. session 20.30.30.80.6-0.10.30.2-0.50.3-0.9-0.7-0.9
Total locomotion distance, hab. session 20.20.31.31.0-0.11.10.10.2-0.00.40.10.3
Locomotion velocity, hab. session 20.20.21.21.1-0.21.00.20.10.00.1-0.00.0
Novel to familiar place preference ratio1.11.13.0-0.0-0.00.5-0.31.1-0.91.71.41.7
Novelty place preference0.80.82.1-0.1-0.10.3-0.21.0-0.81.51.21.4
Time in novel zone, NPP test1.41.43.10.2-0.50.30.21.5-1.31.81.71.7
Total zone transitions, NPP test0.20.31.11.00.00.90.0-0.30.1-0.3-0.4-0.2
Total locomotion distance, NPP test0.60.93.00.70.71.7-0.90.00.21.10.21.1
Locomotion velocity, NPP test0.71.13.10.31.31.8-1.4-0.50.80.9-0.20.9
Intraocular pressure1.92.64.51.1-1.6-0.01.32.1-2.11.62.11.4
Delta distance traveled before/after self-admin0.00.00.00.2-0.1-0.00.1-0.10.1-0.0-0.1-0.0
Delta ambulatory time before/after self-admin0.10.10.20.2-0.10.00.10.2-0.20.50.30.4
Parametrial fat weight7.514.636.06.0-4.92.44.44.0-4.11.63.11.5
Pavlov. Cond. lever latency0.50.62.6-0.6-0.6-1.60.60.7-0.50.20.80.3
Pavlov. Cond. magazine entry latency0.00.10.30.30.10.5-0.1-0.20.1-0.2-0.3-0.2
Pavlov. Cond. change in total contacts0.20.20.60.8-0.40.60.5-0.2-0.0-0.5-0.4-0.6
Pavlov. Cond. index score0.10.20.50.7-0.30.70.3-0.1-0.2-0.3-0.3-0.4
Pavlov. Cond. latency score0.10.10.60.6-0.10.70.1-0.2-0.1-0.3-0.3-0.4
Pavlov. Cond. lever contacts0.20.20.70.7-0.20.80.2-0.1-0.1-0.3-0.3-0.4
Pavlov. Cond. magazine entry number0.10.20.3-0.30.50.2-0.6-0.00.30.60.20.5
Pavlov. Cond. intertrial magazine entries1.01.26.41.30.52.5-0.7-0.10.41.20.00.8
Pavlov. Cond. lever-magazine prob. diff.0.10.20.60.7-0.30.70.4-0.0-0.3-0.3-0.2-0.4
Pavlov. Cond. response bias0.10.20.30.30.10.50.0-0.40.2-0.5-0.6-0.6
Pavlov. Cond. lever latency1.31.83.1-1.11.2-0.1-1.0-1.81.6-1.4-1.7-1.4
Pavlov. Cond. magazine entry latency0.60.72.0-0.1-1.1-1.41.20.8-0.9-0.20.7-0.2
Pavlov. Cond. change in total contacts0.70.91.50.4-1.1-0.81.01.2-1.20.61.20.7
Pavlov. Cond. index score0.81.11.80.7-1.3-0.71.31.3-1.30.51.20.6
Pavlov. Cond. latency score0.80.91.60.5-1.2-0.71.11.3-1.20.51.20.6
Pavlov. Cond. lever contacts0.71.01.71.0-1.00.10.91.3-1.20.81.20.8
Pavlov. Cond. magazine entry number0.30.40.9-0.20.90.9-0.9-0.70.70.1-0.50.0
Pavlov. Cond. intertrial magazine entries0.60.83.21.8-0.61.50.50.6-0.60.60.40.4
Pavlov. Cond. lever-magazine prob. diff.0.60.81.40.5-1.2-0.81.11.1-1.10.31.00.4
Pavlov. Cond. response bias1.01.42.50.7-1.3-0.51.11.6-1.50.91.51.0
Time in closed arm before self-admin0.70.82.00.2-0.6-0.70.9-0.60.4-1.4-1.0-1.3
Time in closed arm after self-admin1.51.62.8-0.90.6-0.9-0.2-1.61.4-1.6-1.7-1.5
Time in open arm before self-admin0.90.92.7-0.71.50.6-1.6-0.10.41.10.31.0
Time in open arm after self-admin1.51.73.8-0.1-0.4-0.30.11.7-1.61.62.01.7
Bone: periosteal estimation1.53.19.03.0-1.62.11.31.6-1.61.41.31.2
Bone: periosteal perimeter2.23.712.03.5-2.61.12.51.6-1.90.21.00.1
Bone: post-yield work1.72.45.81.0-0.02.0-0.41.3-1.02.41.52.3
Progressive ratio test 1 active lever presses0.70.82.0-1.10.0-1.40.2-0.70.6-1.1-0.8-1.0
Progressive ratio test 1 breakpoint0.50.61.8-1.10.1-1.30.1-0.50.4-0.9-0.5-0.7
Progressive ratio test 1 inactive lever presses0.10.20.8-0.6-0.3-0.90.30.1-0.00.20.20.1
Progressive ratio test 2 active lever presses0.70.71.80.4-1.1-0.41.2-0.2-0.0-1.3-0.6-1.2
Progressive ratio test 2 breakpoint0.91.02.30.4-1.4-0.51.5-0.1-0.1-1.5-0.6-1.3
Progressive ratio test 2 inactive lever presses0.20.20.40.1-0.4-0.20.40.5-0.50.60.60.5
Incentive Sensitization - Responses1.61.64.61.1-2.0-0.32.10.3-0.6-1.4-0.3-1.3
Incentive Sensitization - Breakpoint1.61.74.91.2-2.2-0.32.20.5-0.8-1.2-0.0-1.2
Sum of active levers in priming session hrs 5-61.51.44.8-1.1-1.2-2.21.11.1-1.3-0.11.10.2
Progressive ratio1.01.22.7-1.71.6-0.6-1.6-0.30.51.00.21.0
Food seeking constrained by brief footshock0.50.62.7-1.70.8-1.0-0.8-0.30.20.2-0.00.5
Seeking ratio, punishment vs. effort0.50.61.60.5-0.70.30.8-0.50.2-1.3-0.8-1.1
Retroperitoneal fat weight8.828.986.19.3-6.75.36.14.9-4.82.03.31.1
Reaction time number correct0.60.92.40.2-1.2-1.61.40.3-0.6-1.0-0.0-0.7
Reaction time mean minus median0.91.22.91.3-1.5-0.71.70.5-0.7-1.2-0.1-1.0
Reaction time mean minus median AUC1.92.46.70.3-1.3-1.91.7-0.50.1-2.6-1.2-2.3
Reaction time num false alarms0.81.14.31.80.72.1-0.7-0.60.80.3-0.50.2
Reaction time num false alarms AUC1.01.44.51.90.82.1-0.7-1.01.0-0.1-1.0-0.3
Reaction time trials correct on left0.60.92.40.2-1.2-1.61.40.3-0.6-1.0-0.0-0.7
Reaction time trials on left0.71.02.70.2-1.2-1.61.50.4-0.7-1.1-0.0-0.8
Reaction time mean1.82.67.4-0.4-1.1-2.71.5-0.50.0-2.4-1.0-2.2
Reaction time mean AUC2.33.29.0-0.6-1.2-3.01.6-0.60.1-2.7-1.2-2.4
Median of all reaction times2.23.18.2-0.8-0.8-2.91.2-0.90.5-2.7-1.4-2.5
Reaction time omissions1.21.73.91.4-1.9-1.22.00.9-1.3-0.90.4-0.8
Reaction time false alarm rate1.21.77.51.61.22.7-1.3-0.71.00.8-0.50.5
Reaction time premature initiation rate0.60.83.01.40.51.7-0.4-0.70.8-0.2-0.8-0.3
Reaction time premature initiations0.40.51.71.3-0.20.60.4-0.50.4-0.8-0.8-0.7
Std. dev. reaction times1.21.74.21.1-1.9-1.42.10.5-0.8-1.5-0.1-1.3
Reaction time trials completed0.71.02.70.2-1.2-1.61.50.4-0.7-1.1-0.0-0.8
Reaction time trials AUC0.60.92.20.3-1.3-1.51.50.4-0.7-1.00.0-0.7
Run reversals in cocaine runway, females0.20.20.30.4-0.6-0.30.50.5-0.30.40.50.3
Run reversals in cocaine runway, males0.80.81.6-0.80.80.2-0.6-1.20.9-1.0-1.3-0.8
Latency to leave start box in cocaine runway1.21.36.1-0.6-1.0-2.51.20.1-0.3-1.2-0.1-0.9
Latency to leave start box in cocaine runway, F0.80.93.2-0.3-1.2-1.81.30.3-0.5-0.90.1-0.7
Latency to leave start box in cocaine runway, M0.80.82.2-0.5-0.1-1.50.4-0.70.5-1.4-0.9-1.1
Std. dev. time between licks in bursts0.91.12.9-1.00.90.1-1.10.4-0.11.61.01.7
Total sessions with >9 infusions0.70.71.4-0.60.80.3-0.7-1.21.2-0.7-1.2-0.8
Short access day 1 total inactive lever presses0.20.21.0-0.1-0.0-0.1-0.10.3-0.21.00.50.8
Short access day 10 total inactive lever presses0.70.81.51.2-1.10.91.00.8-0.80.60.70.4
Short access day 1 total infusions0.30.30.7-0.20.20.1-0.1-0.80.7-0.6-0.9-0.7
Short access day 10 total infusions1.11.22.4-1.60.9-1.2-0.8-1.31.2-0.9-1.1-0.9
Short access total infusions0.70.81.9-1.40.8-0.8-0.7-1.00.9-0.6-0.9-0.6
Short access day 1 locomotion0.40.41.4-0.4-0.4-1.20.5-0.40.3-0.8-0.5-0.6
Short access day 10 total locomotion0.30.40.8-0.60.3-0.0-0.1-0.70.6-0.8-0.8-0.9
Short access total locomotion2.42.54.1-1.51.2-0.4-0.9-2.01.8-1.8-2.0-1.7
One hour access (0.3 mA shock)1.21.45.3-0.9-1.3-2.31.21.1-1.2-0.21.00.1
Compulsive drug intake0.30.30.60.5-0.5-0.00.40.7-0.70.80.70.7
One hour access (shock baseline)0.40.51.9-1.3-0.0-1.40.1-0.10.1-0.6-0.1-0.5
Social response proportion1.11.12.41.60.01.50.2-1.01.0-0.8-1.2-1.2
Social responses1.21.56.22.5-1.21.71.10.8-0.80.40.50.0
Social time1.21.65.1-0.2-0.6-0.70.9-0.90.6-2.1-1.3-2.3
Soleus weight1.85.413.91.3-2.5-1.63.0-0.5-0.0-3.5-1.6-3.7
Bone: stiffness1.01.65.51.6-0.22.4-0.20.8-0.61.70.91.5
Tibialis anterior weight0.93.17.12.5-2.5-1.12.71.1-1.5-1.20.4-1.4
Time to tail flick, vehicle, before self-admin1.11.12.71.1-0.11.0-0.21.0-0.71.61.11.5
Time to tail flick, vehicle, after self-admin0.20.21.10.6-0.01.1-0.0-0.10.10.3-0.0-0.0
Time to tail flick, test, before self-admin1.51.52.7-0.61.5-0.4-1.2-1.61.6-0.9-1.5-0.8
Time to tail flick, test, after self-admin0.91.01.7-0.3-1.2-0.61.11.3-1.30.61.20.6
Delta time to tail flick, vehicle, before/after SA0.40.41.00.4-0.9-0.21.0-0.0-0.2-0.9-0.3-1.0
Delta time to tail flick, test, before/after SA2.22.03.70.1-1.50.31.11.9-1.91.41.91.2
Tibia length0.10.21.00.60.21.0-0.3-0.00.10.50.00.3
Ambulatory time before self-admin1.21.32.40.30.9-0.1-0.7-1.41.3-1.5-1.5-1.3
Ambulatory time after self-admin1.11.21.8-1.10.8-0.8-0.5-1.41.2-1.3-1.3-1.3
Bone: tissue strength0.20.20.7-0.80.0-0.8-0.00.3-0.30.20.40.3
Total heroin consumption1.92.34.81.5-2.20.02.11.8-1.90.41.40.6
Bone: trabecular number2.13.24.71.9-1.51.51.12.2-1.82.02.11.7
Bone: trabecular spacing0.60.83.2-1.70.7-1.8-0.6-0.30.2-0.3-0.10.1
Bone: trabecular thickness2.53.08.83.0-2.11.51.91.6-1.50.91.20.5
Bone: trabecular tissue density1.62.34.3-1.50.9-1.2-0.6-1.71.5-2.1-1.8-1.8
Water consumed over 24 hours0.40.50.9-0.40.80.3-0.7-0.90.9-0.5-0.8-0.5
Number of responses in last shaping day0.10.10.3-0.60.2-0.4-0.1-0.30.3-0.1-0.2-0.3