Hub : Genes

Fry

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose gene expression Fry 0.26 0.1 0.0e+00 0.24 0.24 0.25 0.24 1.3e-26 6.8e-26 9.4e-28 6.9e-26
2 OFC mRNA stability Fry 0.2 0.1 1.8e-03 0.07 0.12 0.08 0.09 8.2e-03 8.6e-04 5.8e-03 4.4e-03
3 pVTA intron excision ratio chr12_9537627_9547014 0.03 0.02 9.9e-03 0.02 0.02 0 0.02 6.3e-03 1.6e-02 2.2e-01 1.6e-02
4 Eye gene expression Fry 0.47 0.27 2.2e-03 0.23 0.18 0.1 0.18 1.9e-04 8.9e-04 1.2e-02 8.9e-04
5 Adipose alternative TSS XM_039089331.2 0.08 0.06 2.1e-04 0.03 0.03 0.03 0.03 1.1e-04 4.2e-04 7.0e-04 1.0e-04
6 Adipose mRNA stability Fry 0.04 0.03 1.4e-04 0.03 0.02 0.02 0.03 2.5e-04 9.5e-04 3.2e-03 7.9e-04
7 pVTA isoform ratio XM_039089331.2 0.04 0.03 2.0e-03 0.02 0.03 0.01 0.02 7.1e-03 1.5e-03 3.5e-02 4.8e-03
8 pVTA isoform ratio NM_001170398.2 0.04 0.03 1.4e-03 0.02 0.04 0.02 0.03 6.4e-03 7.7e-04 1.3e-02 2.6e-03
9 Brain mRNA stability Fry 0.21 0.09 0.0e+00 0.17 0.22 0.22 0.21 2.9e-15 1.1e-20 8.0e-20 1.3e-19
10 BLA gene expression Fry 0.6 0.1 0.0e+00 0.42 0.45 0.47 0.47 3.6e-24 3.9e-26 2.3e-27 1.8e-27
11 PL mRNA stability Fry 0.09 0.04 1.1e-08 0.04 0.07 0.06 0.06 2.0e-05 1.1e-07 5.7e-07 1.9e-07
12 OFC gene expression Fry 0.45 0.12 3.2e-10 0.37 0.39 0.34 0.38 8.8e-10 2.2e-10 6.1e-09 5.7e-10
13 IL gene expression Fry 0.54 0.12 2.8e-12 0.31 0.38 0.36 0.35 2.9e-08 5.6e-10 1.4e-09 3.3e-09
14 pVTA alternative TSS XM_039089331.2 0.07 0.05 4.1e-03 0.02 0.02 0.04 0.03 1.0e-02 4.3e-03 8.1e-04 2.3e-03
15 RMTg gene expression Fry 0.17 0.09 2.3e-03 0.11 0.1 0.11 0.11 8.0e-04 1.1e-03 7.3e-04 9.7e-04
16 NAcc mRNA stability Fry 0.07 0.03 1.2e-09 0.07 0.06 0.06 0.06 1.7e-10 7.9e-10 1.9e-09 1.8e-09
17 Brain gene expression Fry 0.61 0.09 0.0e+00 0.59 0.65 0.64 0.64 4.7e-68 3.0e-79 1.2e-77 2.0e-77
18 LHb gene expression Fry 0.66 0.15 1.1e-05 0.24 0.17 0.23 0.21 1.9e-06 6.5e-05 4.2e-06 1.2e-05
19 IC gene expression Fry 0.65 0.1 0.0e+00 0.63 0.63 0.67 0.65 1.2e-33 1.2e-33 1.5e-36 4.1e-35
20 NAcc gene expression Fry 0.25 0.08 0.0e+00 0.21 0.2 0.2 0.2 1.5e-31 2.3e-30 6.3e-30 4.0e-30
21 pVTA gene expression Fry 0.51 0.1 0.0e+00 0.43 0.41 0.41 0.43 1.8e-37 6.2e-35 2.2e-35 4.8e-37
22 PL gene expression Fry 0.5 0.07 0.0e+00 0.53 0.55 0.57 0.56 3.7e-68 2.3e-72 1.6e-75 2.5e-74

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22
Bone: apparent density5.79.919.1-4.3-4.4-2.3-4.1-4.4-4.11.4-1.4-3.8-3.2-3.4-3.1-3.0-2.4-3.0-2.8-2.9-2.5-2.8-2.4-2.5-2.4
Area under the delay curve0.60.72.21.41.31.51.31.00.8-0.90.90.80.80.70.60.60.90.30.50.50.50.40.40.50.3
BMI with tail3.211.118.4-4.3-4.2-2.1-4.3-3.6-3.60.7-0.8-4.1-3.6-3.6-3.4-3.5-3.0-2.9-3.8-3.3-3.0-3.1-3.5-2.9-3.0
BMI without tail1.44.314.0-3.0-2.8-3.7-3.2-2.9-3.02.6-2.7-2.1-1.6-1.6-1.0-1.3-2.30.0-1.2-1.2-0.7-0.8-1.2-0.7-0.6
Body weight6.729.269.1-8.3-8.3-7.3-8.1-6.8-6.75.2-5.3-6.1-5.2-5.2-4.2-4.3-4.7-3.0-3.7-3.6-3.3-3.5-3.6-3.3-2.7
Weight adjusted by age0.30.41.5-1.0-0.9-1.1-0.8-1.0-1.21.1-1.1-0.5-0.3-0.10.00.1-0.60.4-0.20.1-0.10.00.10.00.1
Bone surface4.88.818.4-4.1-4.2-2.6-3.9-4.2-4.31.8-1.8-3.6-3.0-3.1-2.7-2.7-2.3-2.5-2.5-2.5-2.1-2.4-2.0-2.1-2.0
Bone volume5.710.217.6-4.0-4.1-1.6-3.8-4.1-4.20.7-0.7-3.9-3.4-3.5-3.4-3.2-2.5-3.3-3.1-3.2-2.8-3.1-2.6-2.8-2.7
Breakpoint value in progressive ratio session0.10.10.4-0.2-0.1-0.5-0.3-0.5-0.40.4-0.40.10.00.10.20.2-0.60.60.10.10.30.10.20.20.2
Number of licking bursts2.54.17.00.50.6-1.90.91.81.82.4-2.51.72.02.12.02.22.71.62.32.32.22.42.22.22.4
Context. condit. distance diff. score3.94.78.2-2.6-2.8-1.4-2.6-2.9-2.90.6-0.5-2.4-2.3-2.7-2.1-2.4-2.6-1.4-1.9-1.9-1.9-2.1-1.8-1.9-1.7
Locomotion velocity, session 10.50.51.50.91.00.50.81.10.9-0.50.40.80.50.80.80.8-0.61.20.10.80.20.40.10.20.1
Locomotion distance, session 10.50.61.91.21.31.21.40.90.9-1.00.90.70.70.80.70.80.20.7-0.10.70.20.40.00.2-0.1
Locomotion velocity, session 22.32.74.21.51.60.11.81.61.80.6-0.61.71.92.01.92.01.61.91.51.91.71.81.41.71.5
Locomotion distance, session 22.53.55.81.92.00.42.41.72.00.4-0.41.92.32.42.22.32.22.01.42.12.02.01.42.01.6
Locomotion velocity, session 30.50.62.2-0.5-0.80.0-0.4-1.2-1.5-0.20.2-0.9-0.6-0.9-0.9-0.9-0.6-0.6-0.6-0.7-0.6-0.7-0.7-0.7-0.7
Locomotion distance, session 30.20.31.8-0.0-0.30.20.0-1.2-1.3-0.30.3-0.5-0.3-0.7-0.5-0.6-0.3-0.2-0.4-0.4-0.3-0.4-0.4-0.2-0.5
Stereotopy head waving bouts, day 30.50.62.0-1.2-1.1-1.4-1.1-1.1-1.11.3-1.3-0.7-0.4-0.6-0.1-0.3-0.90.30.1-0.1-0.1-0.2-0.1-0.10.0
Stereotopy head waving duration, day 30.10.10.3-0.20.00.4-0.20.20.1-0.30.3-0.1-0.3-0.1-0.1-0.1-0.6-0.2-0.2-0.2-0.3-0.4-0.2-0.3-0.3
Locomotion velocity, session 70.50.52.10.70.81.51.00.91.3-1.01.10.60.30.30.20.40.6-0.20.30.40.1-0.00.50.10.1
Locomotion distance, session 70.10.20.60.30.40.80.70.30.8-0.50.60.30.30.00.10.20.6-0.20.30.30.2-0.10.50.20.1
Stereotopy head waving bouts, day 71.31.43.41.81.50.91.50.60.5-0.20.21.41.41.21.31.20.91.51.21.21.31.21.01.31.2
Stereotopy head waving duration, day 71.61.94.22.11.81.31.71.31.2-0.40.41.61.51.61.41.41.21.51.31.31.41.31.11.41.2
Locomotion velocity, session 80.20.20.90.40.4-0.00.30.30.50.2-0.20.50.30.40.60.5-0.20.90.30.60.40.40.40.30.4
Locomotion distance, session 80.50.71.9-1.2-1.2-1.0-0.9-1.4-1.10.7-0.7-1.0-0.7-0.9-0.5-0.6-0.9-0.1-0.9-0.4-0.6-0.6-0.8-0.6-0.6
Degree of sensitization distance1.41.55.51.11.41.01.31.92.4-0.40.31.41.11.41.11.41.20.71.11.10.90.91.10.90.9
Degree of sensitization stereotypy1.01.13.61.91.51.21.60.50.4-0.60.71.21.30.90.90.80.91.10.80.81.20.90.71.10.8
Conditioned locomotion2.32.75.0-1.6-1.3-0.6-1.9-1.8-1.8-0.50.5-1.9-1.9-1.6-1.5-1.5-2.2-1.1-1.8-1.8-1.7-1.7-2.1-1.8-1.8
Cocaine response after cond. corrected0.70.81.7-0.2-0.30.4-0.5-0.9-0.9-0.90.9-0.8-0.9-1.1-1.1-1.2-1.0-1.0-1.0-1.3-1.1-0.9-0.9-1.1-0.9
Cocaine response after cond. not corrected1.61.93.0-0.5-0.60.6-0.8-1.4-1.3-1.31.3-1.3-1.4-1.6-1.5-1.7-1.7-1.3-1.6-1.7-1.5-1.5-1.5-1.5-1.5
Cocaine response before conditioning0.80.91.9-0.7-0.80.2-0.7-1.2-1.2-0.50.5-1.0-0.9-1.0-0.9-0.9-1.4-0.7-1.2-0.8-0.9-1.2-1.1-0.9-1.2
Saline control response1.31.86.9-0.7-0.6-2.0-0.4-0.4-0.52.6-2.60.50.70.51.31.20.31.61.41.61.21.21.51.31.5
Bone: connectivity density5.38.318.6-4.3-4.3-2.8-4.0-4.2-4.02.3-2.3-3.4-2.8-3.0-2.4-2.4-2.3-2.1-2.2-2.1-1.9-2.2-1.8-1.9-1.7
Bone: cortical apparent density0.10.10.70.30.30.40.30.90.7-0.60.60.2-0.00.2-0.1-0.00.3-0.5-0.1-0.1-0.2-0.1-0.2-0.2-0.1
Bone: cortical area1.52.24.9-2.2-2.2-1.5-2.1-1.5-1.80.9-0.9-1.8-1.6-1.6-1.4-1.4-1.1-1.6-1.3-1.3-1.3-1.3-0.9-1.2-1.0
Bone: cortical porosity0.70.81.51.21.00.31.20.60.60.1-0.10.91.20.71.00.71.01.10.60.91.10.90.71.10.7
Bone: cortical porosity0.70.81.81.31.20.71.30.80.7-0.20.21.01.20.80.90.80.90.90.50.91.00.80.71.00.6
Bone: cortical thickness1.52.44.9-2.1-2.2-1.6-1.9-1.8-2.01.0-1.0-1.9-1.5-1.7-1.5-1.5-1.0-1.7-1.5-1.4-1.3-1.3-1.1-1.2-1.1
Bone: cortical thickness0.30.41.8-0.9-0.8-1.3-0.6-0.7-1.21.1-1.1-0.3-0.2-0.4-0.0-0.1-0.2-0.20.10.0-0.0-0.10.30.00.2
Bone: cortical tissue density0.10.10.80.40.40.40.40.90.8-0.60.60.20.10.2-0.10.00.4-0.4-0.0-0.0-0.10.0-0.1-0.2-0.0
Condit. Reinf. active minus inactive responses0.40.41.1-0.7-0.40.3-0.50.30.2-0.70.6-0.7-0.7-0.2-0.7-0.4-0.2-0.8-0.9-0.7-0.9-0.7-1.1-0.8-0.9
Condit. Reinf. active-inactive response ratio0.40.51.2-0.7-0.50.3-0.6-0.0-0.1-0.60.5-0.7-0.8-0.4-0.8-0.6-0.2-1.1-0.8-0.8-0.9-0.8-0.8-0.8-0.9
Condit. Reinf. active responses0.10.10.5-0.2-0.1-0.0-0.30.10.1-0.30.2-0.3-0.30.0-0.3-0.2-0.5-0.1-0.5-0.3-0.5-0.2-0.7-0.4-0.6
Condit. Reinf. inactive responses0.30.41.11.10.90.20.80.60.7-0.10.10.80.70.70.70.5-0.01.10.40.60.50.70.30.50.4
Incentive salience index mean0.70.81.9-0.7-0.50.3-0.7-0.0-0.2-0.80.8-0.9-1.0-0.7-0.9-0.8-0.8-1.0-1.3-1.0-1.2-1.0-1.4-1.1-1.3
Condit. Reinf. lever presses0.81.12.0-0.4-0.30.5-0.7-0.3-0.4-1.11.1-1.0-1.1-1.1-1.0-1.2-1.3-1.0-1.4-1.2-1.2-1.2-1.4-1.3-1.4
Condit. Reinf. active minus inactive responses1.11.42.50.40.5-0.90.70.60.41.4-1.31.11.21.01.41.31.11.41.51.61.51.31.41.41.5
Condit. Reinf. active-inactive response ratio1.72.03.71.01.1-0.21.21.11.00.8-0.81.61.51.51.81.81.31.61.71.91.71.41.61.61.6
Condit. Reinf. active responses0.40.61.8-0.3-0.2-1.10.1-0.4-0.51.4-1.30.30.50.30.70.60.31.00.80.90.80.70.70.80.8
Condit. Reinf. inactive responses0.50.61.6-1.0-1.1-0.8-0.9-1.3-1.20.5-0.5-0.9-0.7-1.0-0.7-0.8-0.8-0.3-0.6-0.6-0.6-0.5-0.5-0.5-0.6
Condit. Reinf. lever presses1.11.53.2-1.4-1.3-0.3-1.3-1.4-1.8-0.10.1-1.4-1.4-1.3-1.2-1.2-1.3-1.1-1.2-1.1-1.3-1.3-1.3-1.2-1.2
Condit. Reinf. lever reinforcers received0.50.61.5-0.00.0-0.90.3-0.1-0.21.2-1.20.50.70.50.90.90.71.01.01.10.90.80.90.90.9
Conditioned reinforcement - actives0.61.14.6-1.2-1.2-2.1-1.3-1.5-1.71.8-1.7-0.5-0.1-0.5-0.0-0.3-1.10.70.1-0.00.50.20.00.40.4
Conditioned reinforcement - inactives0.50.72.10.80.3-0.71.1-0.1-0.00.8-0.70.71.50.30.60.41.10.50.80.71.41.00.91.21.2
Conditioned locomotion0.70.92.9-0.5-0.7-1.7-0.8-1.6-1.71.6-1.6-0.10.4-0.00.40.1-0.91.20.40.20.90.60.50.60.7
Patch foraging indifference point 0 sec1.93.55.4-2.2-2.1-0.5-2.0-1.7-1.9-0.30.2-2.3-2.1-2.0-2.1-2.0-1.6-2.1-2.1-1.9-2.0-1.9-2.3-2.0-2.0
Patch foraging indifference point AUC0.40.62.1-1.2-1.2-1.4-1.1-1.0-1.01.2-1.2-0.8-0.6-0.7-0.3-0.4-0.4-0.3-0.5-0.2-0.3-0.3-0.2-0.1-0.2
Delay disc. indifference point, 0s delay0.20.21.00.30.31.00.70.60.5-0.40.50.30.20.20.10.30.9-0.10.40.40.20.00.20.10.1
Delay disc. indifference point, 16s delay0.20.21.01.00.51.00.90.2-0.2-0.60.70.20.4-0.10.0-0.10.4-0.2-0.10.10.10.10.10.1-0.1
Delay disc. indifference point, 2s delay0.91.05.61.51.52.41.41.00.9-2.02.00.60.40.50.10.20.5-0.2-0.10.0-0.1-0.2-0.3-0.1-0.4
Delay disc. indifference point, 24s delay1.51.74.12.01.61.52.01.21.2-0.60.61.41.41.21.11.11.50.81.31.21.11.11.21.11.1
Delay disc. indifference point, 4s delay0.60.62.60.80.71.50.70.30.3-1.61.6-0.1-0.3-0.3-0.4-0.4-0.1-0.6-0.7-0.5-0.8-0.6-0.8-0.6-0.9
Delay disc. indifference point, 8s delay0.20.20.40.50.60.60.40.60.4-0.20.20.40.50.50.40.50.60.10.40.20.40.30.40.40.3
Indifference point function ln k0.20.40.70.20.2-0.50.10.80.80.6-0.60.60.50.70.60.60.70.60.90.60.70.70.60.60.8
Indifference point function log k0.20.40.70.20.2-0.50.10.80.80.6-0.60.60.50.70.60.60.70.60.90.60.70.70.60.60.8
Patch foraging total patch changes 0 sec2.24.16.1-2.4-2.3-0.6-2.3-1.8-2.0-0.30.2-2.5-2.4-2.2-2.2-2.1-1.8-2.1-2.3-2.1-2.2-2.0-2.4-2.1-2.1
Patch foraging total patch changes 12 sec4.45.78.4-2.6-2.7-0.8-2.4-2.3-2.4-0.30.3-2.9-2.7-2.8-2.6-2.6-2.1-2.6-2.9-2.3-2.6-2.4-2.7-2.5-2.6
Patch foraging total patch changes 18 sec1.32.03.2-1.5-1.6-0.4-1.4-1.6-1.5-0.10.1-1.8-1.5-1.7-1.5-1.6-1.4-1.4-1.8-1.4-1.6-1.4-1.6-1.3-1.5
Patch foraging total patch changes 24 sec1.52.74.3-1.9-1.8-0.7-2.1-1.5-1.5-0.10.1-1.9-2.0-1.8-1.6-1.6-1.7-1.5-2.0-1.5-1.7-1.7-1.9-1.6-1.8
Patch foraging total patch changes 6 sec1.92.94.3-2.1-2.0-1.1-2.0-1.6-1.70.1-0.2-2.1-2.0-2.0-1.7-1.8-1.7-1.6-1.9-1.7-1.8-1.7-1.8-1.7-1.7
Patch foraging time to switch 0 sec0.71.46.81.41.32.51.30.80.7-2.62.60.3-0.1-0.1-0.4-0.4-0.4-0.8-0.6-0.6-0.7-0.8-0.6-0.8-1.0
Patch foraging water rate 0 sec1.12.38.9-2.3-2.4-3.0-2.5-1.8-1.72.7-2.7-1.3-0.9-0.9-0.4-0.5-0.40.0-0.2-0.2-0.0-0.0-0.10.10.4
Patch foraging water rate 12 sec0.51.13.4-0.2-0.2-1.3-0.3-0.3-0.41.8-1.80.50.71.11.01.10.91.31.31.01.01.21.11.21.4
Patch foraging water rate 18 sec0.71.22.70.60.8-0.60.31.21.30.9-0.91.10.91.41.41.30.71.61.11.31.01.31.01.01.2
Patch foraging water rate 24 sec1.21.67.0-1.0-0.9-2.6-1.3-0.9-0.62.6-2.6-0.00.30.50.90.80.41.30.90.90.91.01.01.01.2
Patch foraging water rate 6 sec0.40.62.0-1.1-1.2-1.0-1.1-1.3-1.41.1-1.1-0.8-0.4-0.4-0.4-0.3-0.20.1-0.3-0.3-0.1-0.2-0.3-0.1-0.1
Seeking ratio, delayed vs. immediate footshock0.40.51.81.01.11.41.11.10.8-1.21.10.60.30.40.20.2-0.10.3-0.10.1-0.0-0.0-0.20.1-0.1
Distance traveled before self-admin0.30.41.40.50.51.20.80.80.9-1.11.20.10.1-0.1-0.3-0.30.3-0.7-0.6-0.3-0.4-0.4-0.5-0.2-0.6
Distance traveled after self-admin0.00.00.1-0.2-0.20.1-0.1-0.3-0.00.0-0.0-0.2-0.1-0.1-0.2-0.2-0.1-0.2-0.0-0.2-0.1-0.1-0.1-0.1-0.2
Extensor digitorum longus weight2.18.319.9-4.0-4.5-3.9-4.1-4.4-3.93.1-3.1-3.1-2.4-3.1-2.3-2.6-2.4-1.5-1.6-2.0-1.0-1.7-1.4-1.3-1.1
Bone: elastic displacement0.91.12.21.10.8-0.41.1-0.10.11.0-0.90.91.50.91.21.00.81.40.91.11.41.41.11.31.2
Bone: elastic work1.31.76.8-1.6-1.8-2.6-1.4-2.1-2.02.4-2.4-1.0-0.3-0.7-0.1-0.3-0.60.1-0.1-0.10.20.10.10.00.3
Bone: endosteal estimation0.40.83.3-0.8-0.9-1.8-0.7-0.7-0.91.8-1.8-0.10.10.10.40.40.20.70.80.50.60.61.00.60.8
Bone: endosteal perimeter0.61.34.0-2.0-1.8-1.6-1.9-1.1-1.31.3-1.3-1.3-1.2-1.1-0.9-0.8-0.7-0.7-0.5-0.8-0.6-0.8-0.3-0.6-0.4
Epididymis fat weight0.93.15.0-2.1-2.1-0.6-2.0-1.7-1.4-0.10.0-2.2-1.9-1.8-2.1-2.0-1.3-1.9-2.0-2.1-1.7-1.8-2.0-1.7-1.8
Delta time in closed arm before/after self-admin0.60.61.4-0.10.1-0.10.20.70.91.0-1.00.60.70.60.70.71.20.60.90.80.90.70.90.91.0
Delta time in open arm before/after self-admin1.31.36.12.01.52.11.50.4-0.1-2.42.50.40.10.0-0.2-0.2-0.7-0.3-0.6-0.4-0.6-0.5-0.5-0.7-0.9
Diff in mean of infusions in LGA sessions0.10.10.5-0.1-0.3-0.5-0.3-0.7-0.40.4-0.4-0.10.0-0.2-0.1-0.2-0.20.30.1-0.20.3-0.00.10.20.2
Delay discount exponential model param0.91.02.8-1.7-1.5-1.6-1.5-1.1-0.91.1-1.1-1.0-0.9-0.8-0.7-0.7-1.0-0.4-0.6-0.6-0.5-0.6-0.5-0.6-0.3
Extinction: sum of active levers before priming0.91.01.6-1.1-1.0-0.1-0.9-1.0-0.9-0.50.4-1.1-1.1-0.8-1.2-1.0-1.1-1.0-1.1-1.3-1.2-1.2-1.1-1.0-1.1
Active lever presses in extinction session 61.01.02.1-1.4-1.4-1.1-1.3-1.5-1.30.5-0.6-1.2-0.9-0.9-1.0-1.0-0.6-1.0-0.9-1.0-0.7-0.6-0.7-0.7-0.6
Bone: final force0.61.04.3-1.7-1.5-2.1-1.5-0.6-0.91.8-1.8-0.6-0.8-0.5-0.1-0.1-0.8-0.10.00.1-0.3-0.20.3-0.30.2
Bone: final moment0.50.84.0-1.4-1.3-2.0-1.3-0.4-0.71.8-1.8-0.5-0.6-0.3-0.0-0.0-0.70.00.10.2-0.2-0.00.4-0.20.3
Food consumed during 24 hour testing period0.30.41.20.60.6-0.50.40.40.50.6-0.60.80.70.50.90.7-0.01.10.20.90.80.70.90.80.6
Glucose0.40.71.91.41.31.01.11.31.1-1.21.20.80.60.90.30.40.60.20.00.30.20.40.10.20.2
Heart weight0.40.61.9-0.3-0.3-0.8-0.20.20.71.4-1.40.40.50.50.60.60.90.71.00.80.80.80.80.91.0
Delay discount hyperbolic model param0.70.72.6-1.5-1.3-1.6-1.3-1.0-0.81.1-1.1-0.8-0.7-0.6-0.5-0.5-0.8-0.3-0.4-0.4-0.3-0.4-0.3-0.4-0.2
Intermittent access intake day 1-15 change0.10.20.9-0.4-0.7-0.5-0.5-1.0-0.80.8-0.8-0.3-0.1-0.3-0.1-0.1-0.20.20.20.00.0-0.0-0.00.10.2
Intermittent access intake escalation0.10.10.7-0.4-0.6-0.4-0.3-0.9-0.60.7-0.6-0.3-0.0-0.4-0.1-0.20.00.00.20.0-0.0-0.1-0.10.00.1
Intermittent access intake escalation 20.00.00.10.00.00.30.1-0.1-0.1-0.20.2-0.0-0.1-0.0-0.00.00.2-0.10.0-0.0-0.2-0.2-0.2-0.0-0.1
Intermitt. access day 1 inactive lever presses0.10.41.20.60.2-0.50.5-0.20.10.7-0.70.60.90.40.60.50.70.40.80.71.10.80.90.90.9
Intermitt. access day 15 inactive lever presses0.30.72.00.50.11.10.3-0.1-0.1-1.41.4-0.4-0.4-0.8-0.9-1.0-0.6-1.1-1.1-0.9-0.8-0.8-0.9-0.7-0.9
Intermitt. access escalation Index0.10.20.50.20.30.10.40.60.50.1-0.10.40.30.40.40.50.70.30.70.50.20.40.40.30.4
Intermittent access day 1 total infusions0.40.71.71.21.30.51.30.70.5-0.40.41.01.10.71.00.80.31.00.70.81.10.70.60.80.7
Intermittent access day 15 total infusions0.30.40.90.70.60.20.9-0.2-0.10.2-0.10.70.90.40.70.50.50.80.80.60.90.60.60.70.7
Intermittent access terminal intake (last 3 days)0.20.30.90.80.80.50.90.0-0.1-0.20.30.60.90.30.60.40.30.60.50.50.80.40.30.50.5
Intermittent access total infusions0.40.41.41.11.00.61.20.20.1-0.40.50.81.00.40.60.40.30.70.60.50.90.50.40.50.5
Intermittent access day 1 locomotion0.40.51.51.21.10.91.20.40.1-0.70.80.80.90.60.60.50.20.50.30.40.80.40.20.40.3
Intermittent access day 15 total locomotion0.71.32.51.41.0-0.11.3-0.1-0.30.6-0.51.31.51.01.31.10.51.51.51.21.61.31.41.31.4
Intermittent access total locomotion0.40.41.51.21.00.71.20.2-0.2-0.50.50.80.90.50.60.50.20.70.50.50.80.50.40.50.4
Intermittent access standard deviation0.10.11.10.40.10.30.4-0.9-1.0-0.20.2-0.00.3-0.1-0.1-0.1-0.20.2-0.1-0.10.1-0.0-0.10.1-0.0
Left kidney weight4.621.352.6-7.1-7.2-6.2-6.6-6.5-6.25.0-5.0-5.2-4.0-4.6-3.5-3.8-3.4-2.5-2.9-2.9-2.3-2.5-2.7-2.5-1.9
Right kidney weight2.913.135.5-5.8-6.0-5.8-5.4-4.7-4.44.9-4.9-3.8-2.8-3.1-2.4-2.5-2.4-1.5-1.6-1.9-1.2-1.4-1.5-1.4-0.8
Cocaine induced anxiety0.50.82.2-0.4-0.40.0-0.8-0.4-0.4-0.80.8-0.8-1.0-0.8-0.8-0.9-1.5-0.5-1.3-0.9-1.0-1.0-1.2-0.9-1.0
Post-drug Anxiety1.61.77.51.11.22.20.61.21.1-2.72.70.1-0.6-0.1-0.6-0.5-1.0-0.7-1.3-0.7-1.2-1.1-1.3-1.2-1.3
Baseline Anxiety2.22.56.72.32.22.42.42.62.5-1.81.81.71.21.50.91.11.60.11.00.90.60.70.80.50.4
Tail length2.18.142.4-3.7-3.5-6.5-3.6-3.3-3.15.6-5.6-1.3-0.8-0.80.40.1-1.71.51.00.50.80.70.70.71.4
Length with tail4.519.668.1-6.7-6.9-8.3-6.5-6.1-5.87.1-7.1-3.9-2.9-3.3-1.7-2.1-3.0-0.4-0.7-1.1-0.8-1.0-0.8-0.80.0
Length without tail5.417.343.9-6.3-6.6-4.7-5.8-5.4-5.13.7-3.7-5.0-4.1-4.5-3.6-3.7-3.2-2.9-2.9-2.8-2.9-2.8-2.8-2.8-2.3
Times rat made contact with spout2.22.64.60.40.5-1.80.50.90.92.1-2.11.41.51.71.71.71.22.01.81.81.81.91.91.81.9
Lifetime Intake0.30.31.11.01.00.71.10.30.2-0.80.80.60.80.30.40.20.00.30.20.20.60.10.10.20.2
Liver weight, left2.33.910.3-3.1-3.2-2.7-2.9-2.4-2.42.2-2.2-2.2-1.8-2.0-1.5-1.6-1.3-1.3-1.1-1.2-1.1-1.1-1.2-1.1-0.7
Liver weight, right2.13.68.6-2.7-2.8-2.7-2.9-2.2-2.21.7-1.8-2.2-2.0-1.6-1.4-1.4-1.9-1.0-1.5-1.2-1.6-1.1-1.5-1.4-1.2
Locomotor activity0.81.35.3-0.5-0.7-2.0-0.4-0.00.12.3-2.30.30.70.40.80.70.71.00.91.01.21.21.11.31.4
Locomotor testing distance0.30.52.5-0.5-0.8-1.6-0.4-0.3-0.41.6-1.6-0.10.3-0.00.20.10.50.50.20.40.60.70.50.80.8
Locomotor testing rearing0.00.00.40.2-0.10.20.4-0.4-0.6-0.10.1-0.10.1-0.1-0.1-0.10.1-0.0-0.2-0.0-0.00.00.10.1-0.1
Locomotion in novel chamber3.03.88.50.70.8-1.90.60.20.12.4-2.51.61.81.82.32.01.02.92.22.12.42.52.32.42.5
Locomotion in novel chamber post-restriction2.54.08.60.20.4-2.60.10.20.22.9-2.91.51.91.92.22.01.02.52.41.92.32.42.42.42.6
Fecal boli incidents, locomotor time 10.30.41.8-0.5-0.7-0.9-0.4-0.7-0.61.3-1.3-0.00.1-0.00.30.20.10.50.60.70.40.40.60.50.6
Change in fecal boli incidents, locomotor task0.20.20.60.70.60.20.40.80.8-0.30.30.50.50.40.30.20.30.20.20.10.30.40.20.30.3
Time >=10cm from walls, locomotor time 10.70.82.5-0.20.21.60.10.60.7-1.51.5-0.3-0.7-0.4-0.7-0.5-0.1-1.3-0.8-0.8-0.8-1.1-0.8-1.0-1.0
Bouts of movement, locomotor time 10.60.73.0-0.9-1.0-1.7-1.0-1.0-1.11.7-1.7-0.4-0.1-0.20.1-0.1-0.20.40.5-0.00.40.30.40.60.6
Total resting periods, locomotor time 10.60.73.0-0.9-1.1-1.7-1.1-1.0-1.21.6-1.6-0.5-0.2-0.3-0.0-0.2-0.30.30.3-0.10.30.20.20.50.5
Rest time, locomotor task time 10.70.82.8-0.5-1.0-1.5-1.2-1.6-1.71.2-1.2-0.8-0.6-0.7-0.2-0.6-1.60.9-0.4-0.3-0.30.0-0.5-0.1-0.1
Distance moved, locomotor task time 10.40.62.00.30.80.70.81.41.4-0.30.30.80.70.90.50.81.4-0.10.60.50.50.40.60.50.4
Vertical activity count, locomotor time 10.20.52.8-0.5-0.1-0.50.20.60.70.9-1.00.40.70.60.40.61.7-0.10.80.50.90.60.80.80.8
Time >=10cm from walls, locomotor time 20.81.22.1-1.0-1.10.5-0.8-1.0-0.9-0.50.5-1.3-1.3-1.2-1.2-1.2-0.8-1.2-1.4-1.1-1.4-1.1-1.4-1.2-1.3
Bouts of movement, locomotor time 20.81.34.5-1.5-1.8-1.4-1.3-2.1-2.01.2-1.2-1.4-0.7-0.9-0.9-0.90.0-0.8-0.4-0.9-0.4-0.5-0.5-0.3-0.3
Total resting periods, locomotor time 20.91.65.1-1.7-1.9-1.3-1.5-2.3-2.21.0-1.0-1.6-1.0-1.2-1.2-1.2-0.3-1.0-0.7-1.2-0.7-0.8-0.7-0.7-0.6
Rest time, locomotor task time 20.91.13.5-0.6-0.50.0-0.9-0.6-0.8-0.80.8-0.9-1.2-1.1-1.0-1.1-1.9-0.5-1.4-1.1-1.4-1.2-1.3-1.3-1.3
Distance moved, locomotor task time 21.82.25.30.40.6-0.50.91.11.21.5-1.51.21.61.71.51.72.31.01.71.61.91.71.71.91.7
Vertical activity count, locomotor time 21.52.16.6-0.6-0.5-1.7-0.1-0.3-0.12.6-2.60.61.20.91.11.11.90.91.81.21.81.51.71.81.9
Light reinforcement 10.41.05.21.41.32.31.71.01.1-1.71.70.70.40.30.20.30.2-0.1-0.30.3-0.1-0.10.1-0.3-0.4
Light reinforcement 20.20.31.20.50.70.80.81.11.1-0.60.60.60.40.30.30.30.50.10.10.30.30.10.40.20.2
Bone: marrow area0.40.83.2-0.8-0.8-1.7-0.7-0.7-0.91.8-1.8-0.10.10.10.40.40.20.70.80.50.60.61.00.60.9
Bone: maximum diameter1.01.94.8-2.2-2.1-1.7-2.1-1.4-1.71.1-1.1-1.6-1.5-1.4-1.2-1.2-0.9-1.2-1.0-1.1-1.0-1.0-0.6-0.9-0.8
Bone: maximum force0.91.64.4-2.1-2.0-1.8-1.8-1.2-1.51.5-1.5-1.3-1.3-1.3-0.8-0.8-1.0-1.0-0.6-0.6-1.0-0.8-0.4-0.9-0.4
Bone: maximum moment0.71.33.4-1.8-1.9-1.7-1.7-1.0-1.31.5-1.4-1.2-1.2-1.1-0.7-0.7-0.9-0.9-0.5-0.5-0.9-0.7-0.3-0.8-0.4
Mean time between licks in bursts0.41.02.21.41.51.11.41.41.3-0.90.81.01.01.00.80.81.20.30.70.60.70.70.60.70.5
Mean num. licks in bursts0.40.72.5-0.2-0.20.5-0.5-1.1-1.2-0.80.8-0.6-0.8-0.8-0.7-0.9-1.6-0.1-0.9-0.9-0.8-0.9-0.8-0.8-0.9
Cd content in liver2.52.84.61.51.4-0.61.51.61.61.1-1.11.72.02.01.91.81.42.11.61.92.02.11.42.01.7
Co content in liver0.81.02.21.00.9-0.70.80.90.90.7-0.61.21.10.81.20.90.21.51.11.01.11.10.81.11.2
Cu content in liver0.00.10.5-0.3-0.3-0.7-0.10.0-0.10.4-0.4-0.1-0.10.2-0.1-0.00.2-0.20.0-0.1-0.10.10.0-0.20.0
Fe content in liver4.25.19.8-3.1-2.9-1.1-2.8-2.0-2.10.2-0.2-2.6-2.7-2.2-2.4-2.2-1.9-2.8-2.1-2.2-2.2-2.5-2.0-2.4-2.1
K content in liver0.30.30.90.20.10.90.2-0.2-0.2-0.80.8-0.2-0.5-0.4-0.3-0.3-0.7-0.1-0.4-0.3-0.9-0.4-0.7-0.6-0.6
Mg content in liver0.10.10.40.40.40.20.50.30.30.00.00.40.30.00.30.1-0.10.60.30.40.10.30.10.40.3
Mn content in liver1.01.12.21.11.21.11.40.70.6-0.20.21.30.91.21.21.40.91.01.51.40.50.91.20.71.1
Na content in liver0.40.40.9-1.0-0.9-0.1-1.0-0.6-0.70.2-0.2-0.7-0.9-0.9-0.6-0.5-0.7-0.6-0.4-0.4-0.7-0.8-0.4-0.8-0.5
Rb content in liver1.01.25.31.01.02.30.80.80.7-2.22.20.0-0.3-0.1-0.5-0.4-0.3-0.9-0.7-0.8-1.0-0.7-0.8-1.0-1.0
Se content in liver5.36.28.3-2.4-2.20.1-2.3-2.1-2.2-1.21.2-2.7-2.8-2.8-2.8-2.7-2.7-2.8-2.8-2.8-2.8-2.9-2.9-2.8-2.7
Sr content in liver0.40.31.0-0.3-0.1-0.7-0.10.40.41.0-1.00.30.30.70.60.7-0.10.80.40.60.50.60.60.40.5
Zn content in liver1.31.47.2-1.6-1.7-2.7-1.7-1.6-1.32.1-2.2-0.9-0.5-0.5-0.3-0.5-0.70.4-0.1-0.4-0.10.2-0.40.10.2
Bone: minimum diameter0.10.21.00.40.40.20.51.00.8-0.00.00.40.40.30.40.40.9-0.00.30.50.40.30.60.40.3
Time in familiar zone, hab. session 10.10.10.6-0.0-0.00.60.10.10.3-0.50.5-0.2-0.2-0.1-0.3-0.10.4-0.8-0.4-0.2-0.3-0.3-0.3-0.3-0.4
Time in novel zone, hab. session 10.20.20.9-0.1-0.2-0.9-0.1-0.1-0.30.9-0.90.10.30.40.30.30.10.80.40.30.50.50.40.50.5
Total zone transitions, hab. session 11.31.83.51.71.91.01.81.41.6-0.50.41.51.41.61.61.70.91.50.81.61.01.10.91.00.8
Total locomotion distance, hab. session 10.30.52.60.70.71.60.9-0.00.1-1.51.5-0.1-0.0-0.2-0.1-0.1-0.2-0.3-0.5-0.1-0.5-0.5-0.6-0.5-0.8
Locomotion velocity, hab. session 10.70.95.31.41.42.31.60.50.5-2.02.00.40.40.00.10.10.1-0.1-0.30.1-0.3-0.3-0.3-0.2-0.6
Time in familiar zone, hab. session 20.10.10.7-0.3-0.30.5-0.1-0.20.1-0.40.4-0.3-0.2-0.1-0.6-0.30.5-0.9-0.1-0.4-0.3-0.4-0.1-0.3-0.2
Time in novel zone, hab. session 20.10.20.50.60.70.10.40.70.5-0.20.20.40.30.20.50.3-0.20.60.00.40.20.40.00.20.1
Total zone transitions, hab. session 21.72.24.41.21.3-0.61.41.01.21.0-1.01.51.71.61.91.81.02.11.32.01.61.71.51.61.5
Total locomotion distance, hab. session 20.60.82.51.31.30.71.60.50.6-0.30.41.01.20.71.00.80.81.00.61.00.80.80.60.90.5
Locomotion velocity, hab. session 20.71.02.91.41.40.71.70.40.5-0.20.21.11.30.81.11.01.01.10.71.11.01.00.81.00.7
Novel to familiar place preference ratio1.51.72.41.51.30.21.51.41.20.3-0.21.51.61.41.31.21.41.41.31.41.41.61.31.41.4
Novelty place preference1.81.92.91.71.50.51.71.71.40.0-0.01.61.61.51.31.31.71.31.31.41.41.61.31.41.4
Time in novel zone, NPP test1.31.42.21.41.20.31.41.51.40.1-0.11.41.41.31.11.11.51.21.11.31.21.41.11.21.2
Total zone transitions, NPP test0.40.51.10.60.5-0.50.60.40.90.7-0.70.60.80.71.00.90.51.00.41.00.80.80.60.80.6
Total locomotion distance, NPP test0.10.20.90.60.50.90.8-0.5-0.2-0.70.8-0.00.2-0.4-0.0-0.2-0.20.0-0.4-0.0-0.1-0.2-0.4-0.1-0.4
Locomotion velocity, NPP test0.10.21.10.80.60.61.0-0.5-0.2-0.20.30.30.7-0.00.40.20.20.50.00.40.40.30.10.40.1
Intraocular pressure1.11.65.7-1.4-1.7-1.2-1.6-2.3-2.40.8-0.7-1.3-1.0-1.6-1.1-1.3-1.3-0.5-0.5-1.1-0.5-0.8-0.6-0.7-0.5
Delta distance traveled before/after self-admin0.20.20.8-0.4-0.4-0.6-0.6-0.7-0.50.9-0.9-0.1-0.10.10.30.3-0.40.60.50.40.20.30.40.10.4
Delta ambulatory time before/after self-admin0.00.00.10.00.00.1-0.10.00.20.1-0.20.1-0.10.20.20.3-0.20.30.10.30.00.20.1-0.00.1
Parametrial fat weight0.61.52.6-1.6-1.20.1-1.4-0.7-1.1-0.50.4-1.4-1.4-1.1-1.4-1.1-0.8-1.6-1.5-1.4-1.2-1.5-1.5-1.4-1.4
Pavlov. Cond. lever latency0.50.72.8-1.2-1.3-1.6-0.6-0.7-0.61.7-1.7-0.4-0.0-0.1-0.20.00.7-0.30.70.20.30.20.50.30.7
Pavlov. Cond. magazine entry latency0.30.31.10.10.2-1.1-0.0-0.0-0.00.9-0.90.40.60.40.70.50.10.90.20.50.80.70.30.90.6
Pavlov. Cond. change in total contacts0.30.31.20.30.40.70.10.2-0.0-1.11.1-0.2-0.3-0.3-0.3-0.4-0.8-0.2-1.0-0.4-0.6-0.5-0.9-0.5-0.9
Pavlov. Cond. index score0.10.10.40.30.40.1-0.1-0.0-0.0-0.40.40.0-0.1-0.10.1-0.1-0.60.3-0.5-0.2-0.1-0.1-0.4-0.0-0.3
Pavlov. Cond. latency score0.10.10.50.50.60.30.00.20.1-0.60.50.10.00.10.2-0.0-0.70.5-0.6-0.1-0.0-0.0-0.3-0.0-0.3
Pavlov. Cond. lever contacts0.50.62.51.21.31.40.60.60.5-1.61.60.40.10.10.1-0.1-0.60.3-0.6-0.2-0.2-0.2-0.5-0.2-0.6
Pavlov. Cond. magazine entry number0.20.20.7-0.1-0.20.90.00.0-0.0-0.70.7-0.3-0.5-0.3-0.5-0.3-0.1-0.8-0.2-0.4-0.6-0.6-0.3-0.7-0.5
Pavlov. Cond. intertrial magazine entries0.10.10.80.20.30.80.20.50.9-0.50.50.2-0.00.30.10.30.2-0.10.10.2-0.2-0.00.0-0.2-0.1
Pavlov. Cond. lever-magazine prob. diff.0.10.10.40.30.40.1-0.1-0.0-0.0-0.50.5-0.0-0.1-0.10.0-0.2-0.70.2-0.5-0.3-0.1-0.2-0.4-0.1-0.4
Pavlov. Cond. response bias0.10.10.40.20.3-0.4-0.1-0.1-0.10.2-0.20.20.20.10.30.1-0.40.6-0.20.10.30.2-0.10.30.1
Pavlov. Cond. lever latency0.10.10.40.30.1-0.40.20.30.60.5-0.50.40.40.30.30.20.50.30.20.40.40.50.50.40.4
Pavlov. Cond. magazine entry latency0.91.13.11.51.51.81.51.51.3-1.41.31.00.91.00.60.81.20.00.60.50.50.40.40.50.3
Pavlov. Cond. change in total contacts0.10.10.30.10.20.20.20.40.30.0-0.00.30.20.40.40.60.40.30.40.50.30.20.30.30.3
Pavlov. Cond. index score0.20.20.90.60.71.00.50.70.5-0.90.80.30.10.40.20.40.2-0.00.10.20.0-0.0-0.10.0-0.0
Pavlov. Cond. latency score0.20.21.00.50.71.00.40.80.6-1.00.90.30.00.30.20.30.1-0.10.00.1-0.1-0.1-0.2-0.1-0.2
Pavlov. Cond. lever contacts0.20.30.5-0.2-0.10.7-0.1-0.4-0.7-0.70.7-0.4-0.5-0.5-0.4-0.4-0.5-0.5-0.4-0.5-0.5-0.7-0.6-0.5-0.6
Pavlov. Cond. magazine entry number0.91.12.4-1.5-1.5-1.5-1.4-1.6-1.31.0-1.0-1.1-1.0-1.1-0.8-1.0-1.5-0.2-0.9-0.7-0.7-0.6-0.7-0.7-0.6
Pavlov. Cond. intertrial magazine entries0.30.52.2-0.6-0.6-1.4-0.6-0.7-0.51.5-1.5-0.0-0.00.00.40.2-0.50.70.30.40.20.50.60.20.5
Pavlov. Cond. lever-magazine prob. diff.0.20.30.90.70.91.00.70.90.7-0.80.70.50.30.60.40.60.50.10.30.40.20.20.10.20.2
Pavlov. Cond. response bias0.20.21.20.30.41.10.40.1-0.2-1.01.0-0.0-0.1-0.1-0.2-0.10.1-0.5-0.1-0.3-0.2-0.4-0.3-0.2-0.3
Time in closed arm before self-admin1.31.74.60.1-0.1-2.00.1-0.1-0.12.1-2.20.61.11.11.31.21.01.61.21.41.31.71.31.61.6
Time in closed arm after self-admin3.13.37.8-0.10.0-1.80.20.70.92.8-2.81.11.61.71.81.92.02.02.02.12.12.12.12.02.3
Time in open arm before self-admin0.10.10.7-0.8-0.3-0.1-0.40.30.60.3-0.3-0.1-0.1-0.1-0.2-0.10.6-0.50.0-0.10.1-0.20.0-0.00.1
Time in open arm after self-admin0.70.83.71.00.81.50.7-0.1-0.3-1.91.9-0.0-0.2-0.3-0.5-0.6-0.6-0.7-0.7-0.8-0.6-0.8-0.8-0.7-1.0
Bone: periosteal estimation0.51.24.2-1.6-1.7-2.0-1.5-1.3-1.61.8-1.8-0.9-0.7-0.8-0.4-0.4-0.3-0.3-0.1-0.3-0.1-0.20.3-0.10.1
Bone: periosteal perimeter1.22.04.4-2.1-2.1-1.0-2.0-1.3-1.50.6-0.6-1.8-1.7-1.7-1.5-1.4-0.8-1.7-1.2-1.3-1.3-1.3-0.9-1.2-1.1
Bone: post-yield work1.92.85.9-1.7-1.7-0.3-1.6-2.0-2.4-0.30.3-2.0-1.7-2.1-1.8-1.9-1.3-1.9-1.9-1.8-1.7-1.7-1.7-1.5-1.6
Progressive ratio test 1 active lever presses0.50.62.4-0.2-0.2-1.5-0.2-0.7-0.81.4-1.30.20.70.30.60.40.01.00.70.41.20.80.51.00.9
Progressive ratio test 1 breakpoint0.50.62.2-0.2-0.2-1.5-0.1-0.7-0.81.3-1.30.30.80.30.60.40.01.00.70.41.20.80.51.00.9
Progressive ratio test 1 inactive lever presses0.50.72.00.40.0-1.10.5-0.5-0.41.1-1.00.41.10.10.50.20.90.70.70.51.41.00.71.31.1
Progressive ratio test 2 active lever presses1.01.22.80.30.1-1.40.2-0.6-0.41.6-1.60.71.20.61.10.80.41.51.21.01.71.31.21.41.4
Progressive ratio test 2 breakpoint1.01.22.80.40.2-1.20.3-0.5-0.31.6-1.50.71.30.61.10.80.51.51.21.01.71.31.21.41.4
Progressive ratio test 2 inactive lever presses0.81.34.7-0.3-0.6-2.2-0.3-1.5-1.32.1-2.10.10.90.00.60.30.31.20.80.61.41.10.81.31.3
Incentive Sensitization - Responses0.10.20.70.90.60.40.6-0.00.3-0.10.10.50.60.30.50.30.10.50.40.30.50.40.40.40.3
Incentive Sensitization - Breakpoint0.10.20.80.90.60.40.60.00.3-0.10.10.50.60.30.50.30.10.50.40.30.50.40.40.40.3
Sum of active levers in priming session hrs 5-62.22.02.9-1.3-1.2-0.1-1.4-1.6-1.7-0.70.6-1.6-1.6-1.4-1.5-1.4-1.3-1.5-1.7-1.6-1.6-1.5-1.6-1.5-1.6
Progressive ratio0.40.72.51.41.20.91.01.61.6-0.90.91.00.60.70.50.40.00.50.20.60.30.50.20.30.2
Food seeking constrained by brief footshock0.20.20.6-0.3-0.20.3-0.3-0.4-0.3-0.40.3-0.6-0.4-0.2-0.5-0.5-0.1-0.5-0.6-0.8-0.7-0.4-0.6-0.6-0.6
Seeking ratio, punishment vs. effort0.50.72.6-1.4-1.1-1.2-0.8-1.6-1.61.4-1.4-0.8-0.1-0.2-0.1-0.00.30.10.2-0.3-0.00.10.10.10.2
Retroperitoneal fat weight1.56.611.1-2.4-2.20.7-2.3-1.6-1.8-1.61.5-2.9-2.9-2.2-3.0-2.7-1.8-3.2-3.2-3.0-3.0-2.9-3.3-2.9-3.1
Reaction time number correct0.40.73.2-0.8-0.9-1.6-0.8-0.8-0.91.8-1.8-0.20.20.10.30.30.60.30.60.30.70.60.60.60.9
Reaction time mean minus median0.51.12.51.61.30.41.50.20.00.00.01.31.30.91.21.00.31.61.11.11.21.11.21.11.1
Reaction time mean minus median AUC0.82.04.72.21.80.92.10.90.6-0.30.31.71.71.21.41.21.11.51.61.41.51.41.61.41.4
Reaction time num false alarms0.40.62.80.70.7-0.20.61.71.60.1-0.10.80.70.70.70.60.20.80.20.80.80.70.30.50.5
Reaction time num false alarms AUC0.10.10.90.00.0-0.5-0.20.90.80.1-0.10.1-0.1-0.00.0-0.1-0.40.2-0.30.10.20.1-0.4-0.1-0.1
Reaction time trials correct on left0.40.73.2-0.8-0.9-1.6-0.8-0.8-0.91.8-1.8-0.20.20.10.30.30.60.30.60.30.70.60.60.60.9
Reaction time trials on left0.40.73.2-0.7-0.8-1.5-0.6-0.7-0.81.8-1.8-0.10.30.20.30.40.70.40.70.40.80.70.70.60.9
Reaction time mean2.53.910.23.13.02.83.22.42.3-2.02.02.21.91.61.51.51.80.91.31.51.11.11.31.11.0
Reaction time mean AUC2.23.59.22.92.92.83.02.32.3-2.02.12.11.81.51.41.41.60.81.11.30.91.01.20.90.9
Median of all reaction times2.94.210.63.13.13.33.22.82.7-2.42.52.11.71.61.31.42.00.41.01.30.80.91.00.80.7
Reaction time omissions0.60.92.81.41.41.41.70.90.8-0.80.81.01.10.80.70.71.00.50.60.70.80.60.60.70.5
Reaction time false alarm rate0.20.21.30.40.40.30.21.11.2-0.70.70.2-0.1-0.0-0.1-0.2-0.60.1-0.5-0.0-0.2-0.2-0.5-0.4-0.4
Reaction time premature initiation rate0.60.92.71.51.61.21.30.60.3-0.80.81.20.70.61.10.9-0.71.70.51.00.60.50.40.50.4
Reaction time premature initiations0.30.52.30.91.00.40.70.2-0.10.1-0.00.90.60.51.00.9-0.41.50.61.00.80.60.50.60.6
Std. dev. reaction times1.12.15.62.32.11.52.41.31.0-0.80.91.71.71.31.41.21.01.41.11.31.21.21.21.11.1
Reaction time trials completed0.40.73.2-0.7-0.8-1.5-0.6-0.7-0.81.8-1.8-0.10.30.20.30.40.70.40.70.40.80.70.70.60.9
Reaction time trials AUC0.30.62.6-0.7-0.8-1.3-0.6-0.7-0.81.6-1.6-0.20.10.10.20.30.60.30.60.30.70.60.50.50.8
Run reversals in cocaine runway, females0.50.52.11.00.71.40.8-0.2-0.1-1.41.50.10.0-0.2-0.2-0.3-0.4-0.3-0.3-0.4-0.4-0.4-0.2-0.5-0.6
Run reversals in cocaine runway, males0.20.20.9-1.0-0.4-0.6-0.50.60.60.7-0.70.0-0.10.20.10.30.6-0.10.40.20.20.10.30.10.3
Latency to leave start box in cocaine runway0.30.41.2-0.3-0.20.7-0.10.81.0-0.80.8-0.2-0.6-0.3-0.8-0.60.2-1.1-0.4-0.6-0.5-0.7-0.5-0.5-0.6
Latency to leave start box in cocaine runway, F0.50.51.6-0.8-0.70.4-0.50.30.8-0.50.5-0.6-0.8-0.7-1.0-0.8-0.0-1.3-0.4-0.8-0.8-0.9-0.7-0.8-0.8
Latency to leave start box in cocaine runway, M0.10.10.40.00.20.00.00.60.2-0.1-0.00.30.00.60.10.30.10.1-0.10.10.20.10.00.30.1
Std. dev. time between licks in bursts0.20.30.60.10.2-0.30.30.60.70.6-0.50.50.50.30.60.50.70.50.70.70.70.50.70.70.7
Total sessions with >9 infusions0.30.31.30.20.30.90.30.20.1-1.11.1-0.1-0.1-0.3-0.4-0.4-0.5-0.6-0.8-0.5-0.2-0.7-0.7-0.6-0.7
Short access day 1 total inactive lever presses0.10.10.3-0.5-0.4-0.3-0.4-0.6-0.30.2-0.2-0.3-0.1-0.4-0.2-0.3-0.4-0.3-0.5-0.30.2-0.2-0.5-0.2-0.1
Short access day 10 total inactive lever presses0.41.03.9-0.6-1.1-0.8-0.8-1.9-2.00.3-0.2-1.0-0.7-1.4-0.9-1.2-1.4-0.4-0.7-0.8-0.6-0.6-0.5-0.7-0.5
Short access day 1 total infusions0.50.62.2-0.00.31.10.20.2-0.0-1.51.5-0.3-0.3-0.4-0.6-0.6-0.5-1.1-1.1-0.8-0.4-0.9-1.0-0.9-1.0
Short access day 10 total infusions0.81.02.4-0.00.11.00.0-0.7-0.9-1.51.6-0.6-0.6-0.9-0.9-1.0-1.5-0.7-1.2-1.1-0.9-1.2-1.4-0.9-1.2
Short access total infusions0.50.62.60.30.61.10.50.20.0-1.61.6-0.1-0.2-0.3-0.5-0.5-0.8-0.7-0.8-0.7-0.4-0.8-0.9-0.7-0.8
Short access day 1 locomotion0.81.02.31.41.40.91.50.90.8-0.50.51.21.31.10.90.91.00.60.60.81.20.80.91.00.7
Short access day 10 total locomotion0.00.10.20.30.00.40.5-0.2-0.3-0.40.4-0.10.3-0.2-0.2-0.20.1-0.3-0.3-0.00.1-0.1-0.20.2-0.2
Short access total locomotion0.30.41.41.11.01.01.20.50.4-1.01.00.60.80.50.30.30.40.1-0.10.20.60.2-0.00.30.0
One hour access (0.3 mA shock)2.83.26.61.31.0-1.01.5-0.3-0.21.8-1.71.62.31.32.01.61.42.32.21.92.62.12.22.32.3
Compulsive drug intake0.60.72.71.01.20.51.01.11.6-0.60.61.00.71.00.70.81.00.30.90.50.50.60.90.60.5
One hour access (shock baseline)0.60.92.30.2-0.0-1.00.4-0.5-0.81.5-1.50.61.20.40.90.60.51.30.91.01.41.10.91.21.2
Social response proportion2.32.77.2-0.2-0.2-2.3-0.1-0.30.02.7-2.61.01.41.01.51.31.31.72.11.61.91.82.11.92.2
Social responses0.70.93.1-0.1-0.4-1.3-0.2-1.1-0.71.8-1.70.40.70.10.70.4-0.01.31.00.81.11.01.11.11.2
Social time2.63.67.82.32.41.82.62.82.4-0.90.92.22.02.01.61.82.61.01.51.71.61.51.51.51.4
Soleus weight1.64.610.1-2.6-3.0-1.7-2.7-3.2-3.01.2-1.2-2.5-2.0-2.5-2.1-2.4-2.0-1.7-1.7-2.1-1.4-1.7-1.7-1.6-1.5
Bone: stiffness0.30.41.2-1.1-1.0-0.6-0.9-0.1-0.50.4-0.3-0.7-0.9-0.8-0.6-0.5-0.6-0.8-0.4-0.3-0.8-0.7-0.4-0.7-0.4
Tibialis anterior weight2.37.818.5-4.1-4.3-4.1-4.0-4.1-4.03.5-3.4-3.0-2.3-2.7-1.8-2.1-2.3-1.0-1.3-1.6-0.9-1.4-1.2-1.1-0.9
Time to tail flick, vehicle, before self-admin0.20.21.00.10.40.60.30.81.0-0.80.70.0-0.30.2-0.10.0-0.3-0.0-0.3-0.1-0.6-0.4-0.5-0.4-0.5
Time to tail flick, vehicle, after self-admin0.20.20.9-0.7-0.50.5-0.50.70.9-0.30.3-0.2-0.6-0.3-0.4-0.1-0.2-0.40.1-0.0-0.4-0.6-0.3-0.7-0.4
Time to tail flick, test, before self-admin0.40.41.7-1.3-1.1-1.0-1.2-0.3-0.11.2-1.2-0.5-0.5-0.3-0.1-0.0-0.5-0.2-0.10.20.0-0.2-0.0-0.2-0.0
Time to tail flick, test, after self-admin0.60.61.20.0-0.01.0-0.10.30.6-1.11.1-0.4-0.7-0.5-0.7-0.7-0.6-0.8-1.1-0.6-1.0-0.8-1.1-0.9-1.0
Delta time to tail flick, vehicle, before/after SA0.20.20.9-0.4-0.60.8-0.30.10.2-0.30.4-0.4-0.4-0.6-0.7-0.50.3-1.00.0-0.2-0.2-0.6-0.3-0.7-0.3
Delta time to tail flick, test, before/after SA0.50.52.11.10.81.30.90.40.3-1.51.50.10.00.0-0.2-0.3-0.1-0.2-0.6-0.4-0.5-0.3-0.6-0.2-0.5
Tibia length1.23.317.1-2.4-2.7-4.1-2.1-1.7-1.63.7-3.7-1.0-0.4-0.5-0.1-0.20.4-0.10.60.20.60.50.70.41.0
Ambulatory time before self-admin0.20.30.70.10.10.70.3-0.0-0.0-0.80.8-0.3-0.2-0.4-0.5-0.5-0.3-0.6-0.8-0.5-0.6-0.6-0.7-0.2-0.7
Ambulatory time after self-admin0.20.20.6-0.2-0.30.3-0.3-0.4-0.3-0.40.4-0.5-0.4-0.4-0.5-0.5-0.8-0.4-0.8-0.5-0.6-0.5-0.7-0.3-0.7
Bone: tissue strength0.50.50.8-0.8-0.9-0.3-0.8-0.5-0.4-0.0-0.0-0.9-0.8-0.7-0.7-0.7-0.7-0.6-0.8-0.5-0.9-0.7-0.9-0.8-0.8
Total heroin consumption0.70.83.51.61.31.91.30.60.7-1.71.70.60.30.30.1-0.0-0.1-0.0-0.4-0.1-0.2-0.0-0.20.1-0.4
Bone: trabecular number3.96.414.1-3.8-3.7-2.2-3.5-3.5-3.31.6-1.6-3.1-2.7-2.5-2.3-2.1-1.9-2.2-2.0-2.0-1.9-2.1-1.8-2.0-1.7
Bone: trabecular spacing1.31.85.31.91.92.31.92.32.0-1.91.91.20.81.00.60.81.00.10.40.70.10.40.40.20.1
Bone: trabecular thickness5.26.513.7-3.5-3.5-2.1-3.3-3.7-3.51.2-1.2-3.0-2.6-2.7-2.5-2.5-2.1-2.2-2.2-2.5-1.9-2.2-2.0-1.9-1.8
Bone: trabecular tissue density0.20.41.20.70.51.10.91.00.9-0.60.70.50.50.10.00.11.1-0.40.40.30.40.10.30.20.3
Water consumed over 24 hours1.72.26.2-0.3-0.2-2.10.10.50.82.5-2.51.01.21.01.51.41.21.51.71.71.71.51.81.71.8
Number of responses in last shaping day0.10.10.30.00.00.40.10.10.1-0.40.4-0.10.0-0.1-0.2-0.20.2-0.3-0.6-0.2-0.0-0.2-0.50.0-0.3