Hub : Genes

Senp1

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 BLA alternative polyA XM_039080358.1 0.05 0.04 3.3e-03 0.04 0.04 0.02 0.03 4.6e-03 3.1e-03 1.8e-02 9.1e-03
2 BLA alternative polyA XM_039080361.1 0.05 0.04 4.6e-03 0.03 0.04 0.01 0.03 6.7e-03 5.2e-03 8.0e-02 1.5e-02
3 PL intron excision ratio chr7_129184152_129188502 0.02 0.02 1.5e-03 0.02 0.02 0.02 0.02 1.6e-03 1.5e-03 2.3e-03 3.2e-03
4 PL isoform ratio XM_039080361.1 0.02 0.02 2.3e-03 0.02 0.02 0.02 0.02 3.8e-03 1.9e-03 3.2e-03 2.3e-03
5 Adipose gene expression Senp1 0.11 0.07 3.1e-15 0.13 0.13 0.13 0.13 7.0e-14 6.9e-14 4.7e-14 5.5e-14
6 BLA isoform ratio XM_039080361.1 0.07 0.05 4.6e-04 0.06 0.07 0.06 0.07 4.3e-04 2.1e-04 2.9e-04 1.7e-04
7 BLA gene expression Senp1 0.1 0.07 1.0e-06 0.14 0.12 0.14 0.14 6.2e-08 3.7e-07 6.3e-08 3.6e-08
8 Brain gene expression Senp1 0.06 0.04 1.6e-07 0.08 0.08 0.07 0.08 6.7e-08 1.3e-07 3.6e-07 7.4e-08
9 Brain alternative polyA XM_039080358.1 0.04 0.03 3.6e-05 0.05 0.05 0.05 0.05 1.5e-05 3.9e-05 1.1e-05 2.5e-05
10 Adipose isoform ratio XM_039080361.1 0.05 0.03 8.6e-07 0.04 0.04 0.04 0.04 9.6e-06 4.5e-05 6.8e-05 3.4e-05
11 NAcc alternative polyA XM_039080361.1 0.05 0.04 9.4e-07 0.06 0.06 0.05 0.06 3.9e-07 4.1e-07 2.1e-06 3.3e-07
12 Brain isoform ratio XM_039080361.1 0.05 0.03 1.2e-05 0.04 0.05 0.04 0.04 5.4e-05 1.5e-05 5.1e-05 5.5e-05
13 NAcc gene expression Senp1 0.02 0.01 8.3e-03 0.02 0.01 0.02 0.02 1.9e-03 6.6e-03 3.9e-03 3.8e-03
14 NAcc alternative polyA XM_039080358.1 0.04 0.03 3.4e-06 0.05 0.05 0.04 0.05 1.3e-06 1.5e-06 1.5e-05 1.2e-06
15 IL gene expression Senp1 0.13 0.1 2.1e-03 0.09 0.1 0.08 0.09 3.9e-03 2.2e-03 5.5e-03 4.3e-03
16 Brain alternative polyA XM_039080361.1 0.04 0.03 2.8e-05 0.05 0.05 0.05 0.05 1.2e-05 3.2e-05 9.4e-06 2.0e-05
17 Adipose alternative polyA XM_039080361.1 0.07 0.05 3.7e-08 0.06 0.05 0.05 0.06 9.3e-07 1.8e-06 2.9e-06 8.2e-07
18 Adipose alternative polyA XM_039080358.1 0.07 0.05 3.3e-08 0.06 0.05 0.06 0.06 7.5e-07 1.6e-06 4.1e-07 7.3e-07
19 PL gene expression Senp1 0.06 0.04 4.0e-07 0.07 0.06 0.06 0.06 5.5e-08 2.4e-07 2.1e-07 1.5e-07
20 pVTA gene expression Senp1 0.11 0.09 2.9e-03 0.01 0.04 0.06 0.03 1.4e-01 9.9e-03 2.1e-03 2.7e-02
21 NAcc isoform ratio XM_039080361.1 0.1 0.07 5.1e-09 0.08 0.07 0.08 0.08 2.9e-09 6.0e-09 8.7e-10 1.5e-09

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21
Bone: apparent density9.115.220.9-3.93.9-3.93.8-4.14.14.2-4.24.1-4.24.13.8-4.1-4.13.6-4.03.93.9-3.1-4.61.2
Area under the delay curve1.31.42.2-1.31.3-1.31.3-1.21.21.1-1.11.3-1.11.21.2-1.1-1.11.2-1.31.10.9-0.9-1.50.3
BMI with tail4.615.018.1-4.24.2-4.24.1-4.14.23.8-3.83.9-3.83.93.9-3.9-3.83.9-3.93.93.6-3.4-4.12.4
BMI without tail0.20.43.5-0.50.5-0.50.5-0.50.70.6-0.60.5-0.50.40.4-0.4-0.30.4-0.50.70.8-0.4-0.91.9
Body weight7.129.633.7-5.75.7-5.75.7-5.55.85.5-5.55.6-5.55.45.5-5.4-5.35.6-5.55.65.4-5.1-5.03.9
Weight adjusted by age2.73.14.6-1.71.7-1.71.8-1.61.91.8-1.81.8-1.81.61.9-1.6-1.61.9-1.91.91.9-2.10.22.1
Bone surface10.818.921.1-4.54.5-4.54.4-4.64.64.6-4.64.5-4.64.54.4-4.5-4.54.2-4.44.44.3-3.7-4.61.7
Bone volume8.013.517.0-3.73.7-3.73.6-3.93.93.9-3.93.9-3.93.93.6-3.8-3.93.4-3.83.73.8-3.1-4.11.3
Breakpoint value in progressive ratio session0.10.20.3-0.40.4-0.40.4-0.40.30.5-0.50.3-0.50.50.4-0.3-0.50.4-0.30.40.4-0.40.0-0.4
Number of licking bursts0.20.32.70.5-0.50.5-0.40.4-0.2-0.10.1-0.20.1-0.3-0.20.40.3-0.20.10.10.4-0.31.61.1
Context. condit. distance diff. score0.40.50.7-0.70.7-0.70.7-0.60.70.9-0.90.7-0.90.60.7-0.6-0.70.7-0.70.80.7-0.6-0.60.4
Locomotion velocity, session 10.90.91.80.9-0.90.9-0.91.1-1.1-1.01.0-0.91.0-1.1-0.91.11.2-0.80.9-1.0-1.10.71.30.3
Locomotion distance, session 13.03.95.31.9-1.91.9-2.02.0-2.1-2.02.0-1.92.0-2.0-2.12.02.0-2.12.0-2.2-2.32.30.7-1.7
Locomotion velocity, session 20.30.40.90.5-0.50.5-0.60.6-0.8-0.40.4-0.50.4-0.6-0.60.70.6-0.60.5-0.8-1.00.80.1-0.8
Locomotion distance, session 22.53.55.01.8-1.81.8-1.91.9-2.0-1.91.9-1.91.9-1.9-2.01.91.9-1.91.9-2.1-2.22.10.8-1.6
Locomotion velocity, session 33.33.84.81.9-1.91.9-2.02.1-2.1-1.81.8-2.01.8-2.1-2.12.12.1-2.02.0-2.1-2.12.20.6-1.5
Locomotion distance, session 34.85.26.02.4-2.42.4-2.42.4-2.4-2.32.3-2.32.3-2.4-2.42.42.4-2.52.3-2.4-2.32.41.1-1.7
Stereotopy head waving bouts, day 30.91.01.8-1.01.0-1.01.0-1.11.00.9-0.91.0-0.91.11.2-1.1-1.21.1-1.00.90.8-1.30.10.7
Stereotopy head waving duration, day 30.30.30.7-0.50.5-0.50.6-0.60.60.5-0.50.6-0.50.60.7-0.6-0.60.6-0.60.40.3-0.80.40.6
Locomotion velocity, session 70.10.11.10.2-0.20.2-0.20.3-0.1-0.10.1-0.20.1-0.3-0.20.20.3-0.10.1-0.00.10.10.21.1
Locomotion distance, session 70.91.21.71.2-1.21.2-1.21.2-1.0-1.11.1-1.11.1-1.3-1.21.21.3-1.11.1-0.8-0.40.90.80.8
Stereotopy head waving bouts, day 70.80.91.8-1.01.0-1.01.1-0.91.00.9-0.90.9-0.91.01.1-0.9-1.11.2-1.00.80.7-1.30.40.8
Stereotopy head waving duration, day 71.21.42.2-1.31.3-1.31.3-1.11.21.2-1.21.1-1.21.21.4-1.1-1.21.5-1.21.10.8-1.50.31.1
Locomotion velocity, session 80.00.10.2-0.30.3-0.30.3-0.10.10.3-0.30.2-0.30.10.2-0.1-0.10.3-0.2-0.1-0.4-0.1-0.3-0.1
Locomotion distance, session 81.11.72.71.2-1.21.2-1.31.3-1.4-1.11.1-1.31.1-1.4-1.41.41.4-1.31.3-1.4-1.51.6-0.0-1.4
Degree of sensitization distance0.90.93.0-0.90.9-0.90.9-0.81.00.8-0.80.9-0.80.80.9-0.9-0.81.0-0.91.21.3-1.0-0.21.7
Degree of sensitization stereotypy0.30.40.8-0.60.6-0.60.7-0.40.50.5-0.50.5-0.50.50.7-0.4-0.50.8-0.60.50.3-0.90.80.9
Conditioned locomotion0.20.23.10.1-0.10.10.0-0.10.1-0.10.10.10.10.20.2-0.1-0.20.2-0.20.10.3-0.71.80.8
Cocaine response after cond. corrected0.30.33.9-0.20.2-0.20.1-0.2-0.1-0.20.2-0.20.20.0-0.1-0.10.0-0.10.2-0.4-0.80.7-2.0-1.1
Cocaine response after cond. not corrected1.01.23.30.8-0.80.8-0.90.7-1.0-1.01.0-1.11.0-0.9-1.10.80.9-1.11.1-1.3-1.51.4-0.9-1.8
Cocaine response before conditioning4.85.88.32.8-2.82.8-2.72.5-2.4-2.32.3-2.42.2-2.4-2.42.42.4-2.62.4-2.3-1.81.92.9-1.2
Saline control response0.00.00.30.2-0.20.2-0.2-0.00.20.1-0.10.1-0.00.1-0.0-0.0-0.1-0.2-0.10.20.50.00.1-0.1
Bone: connectivity density6.39.915.7-3.23.2-3.23.1-3.43.23.4-3.43.3-3.43.33.1-3.3-3.32.9-3.23.02.9-2.4-4.00.7
Bone: cortical apparent density0.40.52.10.8-0.80.8-0.80.7-0.7-0.80.8-0.70.7-0.7-0.70.70.7-0.70.7-0.6-0.50.41.5-0.2
Bone: cortical area10.115.317.1-4.04.0-4.04.0-4.04.14.1-4.14.1-4.14.04.0-4.0-4.03.9-4.14.03.8-3.6-3.42.0
Bone: cortical porosity1.61.83.11.5-1.51.5-1.41.4-1.2-1.51.5-1.31.5-1.3-1.31.31.3-1.41.2-1.2-1.00.91.8-0.4
Bone: cortical porosity2.22.43.71.7-1.71.7-1.61.6-1.4-1.71.7-1.51.8-1.5-1.51.51.5-1.61.5-1.4-1.31.11.9-0.5
Bone: cortical thickness4.37.08.1-2.72.7-2.72.7-2.82.82.8-2.82.8-2.82.82.7-2.8-2.82.6-2.82.62.4-2.3-2.50.9
Bone: cortical thickness0.30.40.9-0.60.6-0.60.6-0.70.60.6-0.60.6-0.60.60.6-0.6-0.60.5-0.60.50.5-0.3-0.9-0.2
Bone: cortical tissue density0.60.72.50.9-0.90.9-0.90.9-0.8-0.90.9-0.80.9-0.8-0.80.80.8-0.80.8-0.7-0.60.51.6-0.2
Condit. Reinf. active minus inactive responses0.20.21.50.3-0.30.3-0.30.2-0.4-0.30.3-0.30.3-0.2-0.40.20.2-0.40.4-0.6-0.80.6-0.2-1.2
Condit. Reinf. active-inactive response ratio0.10.20.8-0.40.4-0.40.3-0.40.30.3-0.30.3-0.30.40.3-0.4-0.40.2-0.2-0.0-0.30.1-0.9-0.8
Condit. Reinf. active responses0.70.91.90.8-0.80.8-0.80.8-1.0-0.90.9-0.90.9-0.8-0.90.70.8-0.90.9-1.2-1.41.00.5-1.3
Condit. Reinf. inactive responses2.63.13.61.8-1.81.8-1.81.8-1.9-1.81.8-1.81.8-1.8-1.81.71.8-1.81.8-1.8-1.71.51.9-0.8
Incentive salience index mean0.10.10.4-0.20.2-0.20.2-0.30.20.3-0.30.3-0.30.30.2-0.4-0.30.1-0.20.0-0.0-0.0-0.4-0.6
Condit. Reinf. lever presses0.30.40.7-0.60.6-0.60.6-0.80.60.7-0.70.7-0.70.70.6-0.8-0.70.5-0.70.50.5-0.6-0.5-0.2
Condit. Reinf. active minus inactive responses0.00.10.40.2-0.20.2-0.10.2-0.1-0.00.0-0.10.0-0.3-0.10.30.3-0.10.10.10.30.00.40.6
Condit. Reinf. active-inactive response ratio0.20.20.40.5-0.50.5-0.50.6-0.6-0.40.4-0.50.4-0.6-0.50.60.6-0.50.6-0.4-0.40.60.5-0.2
Condit. Reinf. active responses0.20.30.50.6-0.60.6-0.60.6-0.5-0.50.5-0.50.5-0.6-0.50.60.7-0.50.5-0.20.00.30.70.4
Condit. Reinf. inactive responses0.81.01.91.1-1.11.1-1.11.1-0.9-1.11.1-1.01.0-1.0-0.91.01.0-1.00.9-0.8-0.50.61.40.1
Condit. Reinf. lever presses0.00.00.20.1-0.10.1-0.10.2-0.1-0.10.1-0.10.1-0.2-0.10.10.2-0.10.10.10.30.20.10.5
Condit. Reinf. lever reinforcers received0.50.71.00.9-0.90.9-0.91.0-0.8-0.80.8-0.90.8-1.0-0.90.91.0-0.80.8-0.6-0.30.70.90.0
Conditioned reinforcement - actives1.41.41.71.3-1.31.3-1.31.3-1.3-1.11.1-1.21.1-1.2-1.21.11.1-1.21.2-1.1-1.01.11.2-0.7
Conditioned reinforcement - inactives1.31.51.71.2-1.21.2-1.21.3-1.3-1.31.3-1.31.3-1.3-1.31.21.3-1.31.2-1.3-1.31.20.4-0.5
Conditioned locomotion0.30.41.30.7-0.70.7-0.60.7-0.5-0.50.5-0.50.5-0.6-0.50.60.6-0.50.5-0.3-0.10.31.20.7
Patch foraging indifference point 0 sec1.52.43.61.6-1.61.6-1.71.9-1.5-1.31.3-1.61.3-1.8-1.71.91.9-1.61.6-1.3-1.21.70.70.6
Patch foraging indifference point AUC0.20.20.90.4-0.50.5-0.40.5-0.5-0.50.5-0.40.5-0.6-0.40.70.6-0.30.4-0.4-0.30.20.90.2
Delay disc. indifference point, 0s delay1.41.52.1-1.31.3-1.31.3-1.31.31.0-1.01.3-1.11.21.3-1.2-1.21.4-1.41.31.1-1.4-0.61.3
Delay disc. indifference point, 16s delay1.61.62.0-1.31.3-1.31.3-1.21.31.4-1.41.4-1.31.21.3-1.2-1.11.3-1.41.31.3-1.2-1.01.3
Delay disc. indifference point, 2s delay0.91.01.3-1.11.1-1.11.1-1.11.00.8-0.81.1-0.91.11.1-1.0-1.21.1-1.11.00.9-1.1-0.60.2
Delay disc. indifference point, 24s delay1.61.52.1-1.31.3-1.31.3-1.21.21.4-1.41.4-1.31.21.3-1.2-1.11.3-1.41.31.3-1.2-0.90.7
Delay disc. indifference point, 4s delay0.40.42.1-0.70.7-0.70.6-0.60.40.6-0.60.6-0.60.60.5-0.5-0.60.5-0.60.50.3-0.1-1.4-0.5
Delay disc. indifference point, 8s delay3.23.34.8-2.02.0-2.02.0-1.91.81.8-1.82.0-1.71.81.8-1.8-1.81.8-1.91.71.5-1.5-2.20.4
Indifference point function ln k3.65.05.7-2.32.3-2.32.3-2.22.42.4-2.42.3-2.32.22.2-2.3-2.12.3-2.32.22.1-2.1-1.72.1
Indifference point function log k3.65.05.7-2.32.3-2.32.3-2.22.42.4-2.42.3-2.32.22.2-2.3-2.12.3-2.32.22.1-2.1-1.72.1
Patch foraging total patch changes 0 sec1.42.33.51.6-1.61.6-1.61.9-1.4-1.31.3-1.61.3-1.8-1.71.91.8-1.61.6-1.3-1.11.50.80.7
Patch foraging total patch changes 12 sec1.41.82.71.4-1.41.4-1.41.6-1.3-1.31.3-1.31.2-1.5-1.41.71.4-1.31.3-1.2-1.01.21.6-0.2
Patch foraging total patch changes 18 sec3.34.26.62.2-2.22.2-2.22.4-1.9-1.91.9-2.01.9-2.4-2.12.62.5-2.02.0-1.6-1.21.72.11.2
Patch foraging total patch changes 24 sec1.31.52.81.3-1.31.3-1.31.6-1.1-1.11.1-1.21.0-1.5-1.21.61.5-1.11.1-0.8-0.40.71.71.5
Patch foraging total patch changes 6 sec2.03.03.91.9-1.91.9-1.92.0-1.8-1.71.7-1.81.6-2.0-1.91.91.9-1.91.8-1.6-1.21.81.1-0.7
Patch foraging time to switch 0 sec2.84.34.92.2-2.22.2-2.22.1-2.2-2.12.1-2.12.2-2.0-2.12.01.8-2.22.1-2.1-1.81.82.0-1.7
Patch foraging water rate 0 sec3.86.27.0-2.62.6-2.62.6-2.52.62.5-2.52.5-2.52.32.5-2.4-2.22.6-2.52.52.3-2.4-2.12.5
Patch foraging water rate 12 sec3.65.56.0-2.42.4-2.42.4-2.42.32.4-2.42.4-2.42.32.4-2.4-2.22.4-2.42.42.5-2.3-1.81.7
Patch foraging water rate 18 sec0.60.81.0-1.01.0-0.90.9-0.80.80.9-0.90.8-0.90.80.9-0.9-0.81.0-0.80.90.8-0.7-1.00.6
Patch foraging water rate 24 sec2.94.14.9-2.12.1-2.02.1-2.02.12.0-2.02.1-2.02.02.2-2.2-2.02.2-2.12.01.8-2.2-0.52.1
Patch foraging water rate 6 sec3.95.76.6-2.52.5-2.52.5-2.52.42.5-2.52.4-2.52.42.5-2.5-2.32.6-2.42.42.2-2.4-1.61.6
Seeking ratio, delayed vs. immediate footshock0.30.42.4-0.60.6-0.60.5-0.80.50.3-0.30.4-0.30.60.4-0.7-0.60.4-0.40.1-0.20.0-1.5-0.8
Distance traveled before self-admin0.91.02.51.1-1.11.1-1.01.1-0.9-1.01.0-1.01.0-1.1-0.91.01.0-0.91.0-0.9-0.80.61.60.2
Distance traveled after self-admin0.20.21.00.4-0.40.4-0.40.4-0.3-0.30.3-0.40.3-0.5-0.40.50.5-0.40.4-0.4-0.50.50.31.0
Extensor digitorum longus weight5.220.424.4-4.94.9-4.94.9-4.44.74.6-4.64.6-4.64.54.7-4.5-4.54.9-4.64.74.2-4.3-3.33.1
Bone: elastic displacement4.65.26.22.5-2.52.4-2.42.5-2.3-2.42.4-2.22.3-2.4-2.42.42.4-2.42.2-2.3-2.02.12.0-0.7
Bone: elastic work0.00.00.10.3-0.30.3-0.30.3-0.2-0.20.2-0.10.2-0.2-0.20.20.2-0.30.1-0.10.00.10.30.1
Bone: endosteal estimation6.714.616.9-4.04.0-4.04.0-3.93.93.9-3.93.9-3.93.94.0-3.8-3.94.1-3.94.03.8-3.8-2.52.7
Bone: endosteal perimeter6.613.715.7-3.93.8-3.83.9-3.83.83.8-3.83.8-3.83.83.9-3.8-3.83.9-3.84.03.9-3.6-2.42.3
Epididymis fat weight0.41.02.6-1.11.1-1.11.0-0.81.10.9-0.91.0-0.90.60.8-0.8-0.51.0-0.91.00.9-0.7-1.61.5
Delta time in closed arm before/after self-admin0.50.54.1-0.40.4-0.40.3-0.40.30.4-0.40.3-0.40.50.2-0.5-0.50.2-0.30.30.20.2-1.7-2.0
Delta time in open arm before/after self-admin3.93.85.72.0-2.02.0-2.02.0-1.9-2.12.1-1.92.1-2.0-1.91.92.0-1.91.9-2.0-2.01.72.40.2
Diff in mean of infusions in LGA sessions1.21.42.5-1.21.2-1.21.1-1.21.11.0-1.01.1-1.01.41.1-1.3-1.51.1-1.11.00.9-0.7-1.3-1.6
Delay discount exponential model param1.11.22.01.2-1.21.2-1.21.1-1.0-1.11.1-1.21.0-1.1-1.11.01.1-1.11.2-1.0-0.80.81.4-0.1
Extinction: sum of active levers before priming0.40.40.6-0.70.7-0.70.7-0.60.70.5-0.50.6-0.50.70.7-0.6-0.70.7-0.60.50.5-0.70.10.5
Active lever presses in extinction session 60.40.40.7-0.70.7-0.70.7-0.60.60.8-0.80.7-0.80.60.6-0.6-0.70.6-0.60.60.5-0.3-0.50.5
Bone: final force9.715.718.1-4.24.2-4.14.1-4.14.14.3-4.34.2-4.34.14.0-4.1-4.14.0-4.13.93.6-3.4-3.91.7
Bone: final moment9.815.818.1-4.24.2-4.24.1-4.14.14.3-4.34.2-4.34.14.0-4.1-4.14.0-4.13.93.6-3.3-4.11.7
Food consumed during 24 hour testing period1.31.64.0-1.41.4-1.31.3-1.31.21.3-1.31.2-1.31.31.2-1.2-1.41.1-1.21.11.1-0.6-2.0-0.2
Glucose0.20.30.8-0.40.4-0.40.4-0.50.50.5-0.50.4-0.50.60.5-0.5-0.60.5-0.50.70.9-0.7-0.10.1
Heart weight0.10.23.0-0.10.1-0.10.0-0.1-0.2-0.20.2-0.20.20.1-0.0-0.1-0.2-0.10.2-0.2-0.30.3-0.4-1.7
Delay discount hyperbolic model param1.01.11.91.2-1.21.2-1.11.1-1.0-1.01.0-1.11.0-1.0-1.01.01.0-1.01.1-1.0-0.80.81.4-0.1
Intermittent access intake day 1-15 change1.11.12.41.0-1.01.0-1.00.9-1.1-1.01.0-1.11.0-0.9-1.10.90.9-1.11.1-1.0-1.01.20.2-1.5
Intermittent access intake escalation0.80.82.60.8-0.80.8-0.80.7-0.9-0.90.9-0.90.9-0.8-0.90.70.7-0.90.9-0.8-0.81.0-0.1-1.6
Intermittent access intake escalation 21.11.12.81.0-1.01.0-1.11.0-1.1-1.01.0-1.11.0-0.9-1.10.90.9-1.11.1-1.0-1.01.20.1-1.7
Intermitt. access day 1 inactive lever presses3.23.47.42.0-2.02.0-1.92.1-1.8-1.81.8-1.91.8-2.0-1.82.02.0-1.71.8-1.6-1.41.32.70.3
Intermitt. access day 15 inactive lever presses1.01.11.71.1-1.11.1-1.01.2-1.0-1.01.0-1.01.0-1.2-1.01.31.2-1.01.0-1.0-0.90.71.10.4
Intermitt. access escalation Index0.20.20.40.5-0.50.5-0.50.5-0.5-0.30.3-0.50.3-0.5-0.40.50.5-0.40.5-0.3-0.20.20.60.3
Intermittent access day 1 total infusions1.21.41.61.2-1.21.2-1.21.2-1.2-1.21.2-1.21.2-1.2-1.21.11.2-1.31.2-1.2-1.21.20.7-0.7
Intermittent access day 15 total infusions2.02.32.81.6-1.61.6-1.61.5-1.6-1.51.5-1.61.5-1.5-1.61.41.5-1.71.6-1.4-1.31.50.9-1.4
Intermittent access terminal intake (last 3 days)2.22.42.91.7-1.71.7-1.71.6-1.6-1.51.5-1.61.5-1.6-1.71.51.6-1.71.6-1.5-1.41.60.9-1.0
Intermittent access total infusions2.12.32.81.6-1.61.6-1.61.5-1.6-1.51.5-1.61.5-1.6-1.61.51.6-1.71.6-1.5-1.41.51.1-0.8
Intermittent access day 1 locomotion0.80.92.71.1-1.11.1-1.01.0-0.9-0.90.9-0.90.9-1.0-0.90.91.1-0.90.8-0.6-0.40.41.60.9
Intermittent access day 15 total locomotion0.90.93.11.1-1.11.1-1.01.1-0.9-0.70.7-0.90.7-1.1-0.91.01.2-0.90.8-0.5-0.20.31.81.2
Intermittent access total locomotion2.42.77.61.9-1.91.8-1.71.9-1.6-1.51.5-1.61.5-1.9-1.61.71.9-1.51.5-1.2-0.80.92.81.2
Intermittent access standard deviation0.60.72.60.7-0.70.7-0.80.6-0.8-0.80.8-0.80.8-0.6-0.70.60.5-0.80.9-0.9-0.90.90.4-1.6
Left kidney weight0.41.27.6-1.21.2-1.21.0-1.10.80.8-0.80.8-0.81.00.8-1.1-1.10.8-0.80.60.4-0.1-2.8-1.1
Right kidney weight2.88.09.1-3.03.0-3.03.0-2.92.92.8-2.82.8-2.82.82.9-3.0-2.93.0-2.82.92.9-2.7-2.71.5
Cocaine induced anxiety1.01.21.7-1.11.1-1.11.1-1.11.11.1-1.11.1-1.11.21.2-1.2-1.21.2-1.11.21.3-1.2-0.40.4
Post-drug Anxiety3.94.35.2-2.22.2-2.22.2-2.32.22.0-2.02.1-2.02.32.2-2.2-2.32.2-2.22.22.1-2.2-1.21.0
Baseline Anxiety1.11.21.5-1.11.1-1.21.1-1.21.21.1-1.11.2-1.11.11.1-0.9-1.01.1-1.21.00.7-1.0-1.20.7
Tail length0.10.22.30.3-0.30.3-0.30.4-0.2-0.00.0-0.20.1-0.4-0.30.30.5-0.20.20.10.40.10.31.5
Length with tail2.17.69.0-2.92.9-2.92.9-2.72.82.8-2.82.9-2.82.72.8-2.7-2.72.9-2.93.03.0-2.6-2.42.0
Length without tail7.015.218.6-4.34.3-4.34.2-4.13.93.8-3.84.0-3.94.14.0-4.0-4.14.1-4.03.93.4-3.4-4.10.3
Times rat made contact with spout0.00.10.6-0.20.2-0.20.1-0.00.00.2-0.20.1-0.1-0.1-0.00.20.10.1-0.0-0.1-0.30.4-0.80.0
Lifetime Intake1.61.82.21.4-1.41.4-1.41.4-1.4-1.41.4-1.41.4-1.4-1.41.31.4-1.51.4-1.3-1.21.30.9-0.5
Liver weight, left2.03.34.1-1.81.8-1.81.8-1.91.91.9-1.91.8-1.81.91.8-1.9-1.91.8-1.81.92.0-1.7-1.80.5
Liver weight, right2.03.23.8-1.81.8-1.81.8-1.81.92.0-2.01.8-1.91.81.8-1.8-1.71.8-1.81.91.8-1.8-1.71.1
Locomotor activity0.71.12.51.2-1.21.2-1.11.2-1.1-1.01.0-1.01.1-1.1-1.01.01.0-1.11.0-1.0-0.90.91.60.2
Locomotor testing distance2.23.75.02.1-2.12.1-2.12.1-1.9-1.81.8-2.01.9-2.1-2.02.02.1-2.02.0-1.8-1.71.62.20.2
Locomotor testing rearing1.92.96.32.0-2.02.0-1.91.9-1.6-1.51.5-1.71.5-1.9-1.71.71.9-1.71.7-1.4-1.01.22.50.9
Locomotion in novel chamber0.60.81.1-1.01.0-1.01.0-0.91.00.9-0.90.9-0.80.81.0-0.8-0.81.0-0.90.80.7-1.1-0.30.4
Locomotion in novel chamber post-restriction0.50.65.9-0.70.7-0.70.7-0.40.80.6-0.60.7-0.60.20.6-0.4-0.00.7-0.70.60.5-0.7-0.32.4
Fecal boli incidents, locomotor time 11.21.42.90.9-0.90.9-1.00.9-1.1-1.11.1-1.01.2-1.0-1.31.01.0-1.31.1-1.4-1.61.7-1.2-1.4
Change in fecal boli incidents, locomotor task0.90.81.1-0.90.9-0.90.9-0.91.00.8-0.81.0-0.70.91.0-0.9-1.01.0-1.00.80.8-1.0-0.11.0
Time >=10cm from walls, locomotor time 10.50.51.6-0.70.8-0.80.7-0.70.70.8-0.80.7-0.70.60.6-0.7-0.50.6-0.70.60.5-0.5-1.30.8
Bouts of movement, locomotor time 10.20.21.4-0.40.4-0.50.4-0.40.30.5-0.50.4-0.50.30.3-0.5-0.20.3-0.40.20.0-0.2-1.20.3
Total resting periods, locomotor time 10.10.10.60.1-0.10.1-0.20.1-0.3-0.10.1-0.10.0-0.2-0.30.10.3-0.30.2-0.3-0.50.3-0.80.0
Rest time, locomotor task time 10.10.10.30.2-0.20.2-0.30.3-0.4-0.40.4-0.30.4-0.4-0.40.30.5-0.30.3-0.5-0.60.4-0.50.3
Distance moved, locomotor task time 10.10.20.90.4-0.40.4-0.30.3-0.3-0.30.3-0.40.3-0.2-0.20.30.1-0.30.4-0.10.10.10.9-0.9
Vertical activity count, locomotor time 11.11.22.4-1.11.1-1.11.1-1.21.11.0-1.01.0-1.01.21.0-1.2-1.31.0-1.00.90.8-0.7-1.5-1.3
Time >=10cm from walls, locomotor time 20.30.30.50.5-0.50.5-0.50.6-0.5-0.60.6-0.50.7-0.5-0.50.60.6-0.50.5-0.7-0.70.60.30.3
Bouts of movement, locomotor time 22.93.13.8-1.81.8-1.81.9-1.71.91.8-1.81.9-1.81.71.9-1.8-1.62.0-1.91.91.7-2.0-0.61.3
Total resting periods, locomotor time 23.23.44.2-1.91.9-1.91.9-1.82.01.9-1.92.0-1.91.81.9-1.9-1.72.0-2.02.01.8-2.0-0.71.4
Rest time, locomotor task time 20.20.20.8-0.50.5-0.50.5-0.50.40.6-0.60.5-0.60.40.4-0.5-0.30.4-0.50.50.4-0.4-0.90.4
Distance moved, locomotor task time 20.40.40.70.6-0.60.6-0.60.6-0.7-0.80.8-0.70.9-0.5-0.60.60.5-0.60.7-0.6-0.60.50.8-0.8
Vertical activity count, locomotor time 20.10.10.2-0.40.4-0.40.4-0.30.30.3-0.30.4-0.30.30.4-0.3-0.20.4-0.40.40.4-0.4-0.20.3
Light reinforcement 12.34.17.62.4-2.42.4-2.32.4-2.1-2.02.0-2.02.0-2.1-2.12.22.1-2.11.9-1.5-0.91.42.80.3
Light reinforcement 20.70.91.11.1-1.11.1-1.01.1-1.0-1.01.0-1.01.0-0.8-1.00.80.8-1.00.9-0.9-0.70.80.7-0.9
Bone: marrow area6.714.416.9-4.04.0-4.04.0-3.83.93.9-3.93.8-3.93.84.0-3.8-3.84.1-3.84.03.8-3.8-2.42.8
Bone: maximum diameter4.58.39.3-3.03.0-3.03.0-2.93.02.9-2.93.0-2.92.93.0-2.9-2.93.1-3.03.02.9-2.8-2.22.2
Bone: maximum force12.822.125.0-4.84.8-4.84.8-4.84.95.0-5.04.9-5.04.84.8-4.8-4.84.7-4.94.94.7-4.2-4.12.6
Bone: maximum moment12.721.924.8-4.84.8-4.84.8-4.84.85.0-5.04.9-5.04.84.7-4.8-4.84.7-4.94.84.6-4.2-4.22.5
Mean time between licks in bursts0.30.40.70.8-0.70.7-0.70.6-0.6-0.80.8-0.70.7-0.5-0.60.50.5-0.70.6-0.7-0.50.50.8-0.2
Mean num. licks in bursts0.30.43.5-0.20.2-0.2-0.0-0.0-0.2-0.20.2-0.20.2-0.1-0.30.10.1-0.20.3-0.6-1.01.0-1.9-1.5
Cd content in liver0.30.30.40.5-0.50.5-0.50.6-0.6-0.60.6-0.60.6-0.6-0.60.60.5-0.50.6-0.6-0.60.60.3-0.1
Co content in liver0.00.00.10.4-0.40.3-0.30.2-0.2-0.10.1-0.10.1-0.1-0.20.10.1-0.30.1-0.20.10.10.2-0.1
Cu content in liver1.21.41.7-1.31.3-1.31.3-1.31.21.3-1.31.2-1.31.31.2-1.2-1.31.3-1.21.00.7-1.0-1.20.1
Fe content in liver0.10.10.10.3-0.30.3-0.30.3-0.2-0.20.2-0.20.2-0.3-0.30.30.3-0.30.3-0.3-0.20.30.30.0
K content in liver0.80.82.1-1.11.1-1.11.0-0.80.90.9-0.90.9-0.90.80.9-0.7-0.81.0-0.90.70.4-0.6-1.40.2
Mg content in liver0.00.10.5-0.20.2-0.20.1-0.10.1-0.00.00.10.00.10.1-0.0-0.10.1-0.1-0.1-0.2-0.0-0.7-0.6
Mn content in liver0.10.10.4-0.30.3-0.30.3-0.00.20.2-0.20.2-0.20.00.2-0.1-0.00.4-0.20.2-0.0-0.3-0.10.6
Na content in liver0.00.00.3-0.30.3-0.20.20.0-0.0-0.20.2-0.10.20.00.20.0-0.00.30.00.0-0.2-0.10.60.3
Rb content in liver0.00.00.10.2-0.20.2-0.20.3-0.1-0.20.2-0.10.2-0.3-0.20.30.3-0.10.1-0.1-0.1-0.00.30.2
Se content in liver0.40.50.80.6-0.60.6-0.60.7-0.7-0.70.7-0.70.7-0.7-0.70.70.7-0.70.7-0.7-0.70.8-0.4-0.9
Sr content in liver1.00.92.7-0.90.9-0.90.9-0.80.90.9-0.90.9-0.90.80.9-0.8-0.80.9-0.91.11.1-1.0-0.81.6
Zn content in liver0.80.92.10.8-0.80.8-0.81.1-0.9-0.90.9-0.90.9-1.1-0.81.11.1-0.70.9-0.8-0.80.61.41.1
Bone: minimum diameter8.215.417.7-4.04.0-4.04.0-4.14.24.1-4.14.1-4.14.14.1-4.1-4.14.0-4.14.04.0-4.0-2.32.4
Time in familiar zone, hab. session 10.50.41.30.4-0.40.4-0.50.6-0.7-0.70.7-0.60.7-0.6-0.60.60.6-0.60.7-0.9-1.10.9-0.1-0.7
Time in novel zone, hab. session 10.50.51.6-0.30.3-0.30.4-0.50.70.7-0.70.7-0.70.50.6-0.6-0.50.5-0.70.91.3-1.10.61.0
Total zone transitions, hab. session 10.20.30.50.6-0.60.6-0.60.7-0.6-0.40.4-0.40.4-0.7-0.60.70.7-0.60.4-0.4-0.20.50.40.2
Total locomotion distance, hab. session 10.00.00.30.2-0.20.2-0.20.1-0.1-0.20.2-0.10.2-0.1-0.20.10.1-0.20.1-0.2-0.10.2-0.2-0.5
Locomotion velocity, hab. session 10.00.00.10.1-0.10.1-0.10.0-0.0-0.00.0-0.00.00.0-0.10.0-0.0-0.10.0-0.00.10.1-0.1-0.4
Time in familiar zone, hab. session 20.20.21.1-0.30.3-0.30.3-0.40.40.4-0.40.4-0.40.40.2-0.4-0.40.1-0.30.30.4-0.0-1.0-0.1
Time in novel zone, hab. session 20.30.32.80.3-0.30.3-0.20.5-0.4-0.50.5-0.40.5-0.4-0.20.50.40.00.3-0.2-0.3-0.31.70.5
Total zone transitions, hab. session 20.20.20.60.3-0.30.3-0.40.5-0.5-0.30.3-0.30.3-0.5-0.50.50.6-0.50.3-0.5-0.70.8-0.5-0.3
Total locomotion distance, hab. session 20.20.20.50.4-0.40.4-0.40.4-0.4-0.50.5-0.40.5-0.4-0.50.40.4-0.50.5-0.6-0.70.7-0.3-0.6
Locomotion velocity, hab. session 20.10.10.40.1-0.10.1-0.20.2-0.2-0.30.3-0.20.3-0.2-0.30.20.2-0.30.3-0.5-0.60.5-0.6-0.5
Novel to familiar place preference ratio2.02.14.5-1.11.1-1.21.2-1.31.51.6-1.61.5-1.61.31.4-1.3-1.31.3-1.51.72.1-1.7-0.41.5
Novelty place preference1.51.53.8-0.90.9-0.91.0-1.11.31.4-1.41.3-1.41.11.2-1.0-1.11.1-1.31.52.0-1.5-0.21.5
Time in novel zone, NPP test1.31.33.7-0.70.7-0.70.9-0.91.21.2-1.21.2-1.21.01.0-0.9-0.91.0-1.21.51.9-1.50.11.6
Total zone transitions, NPP test1.01.52.31.1-1.11.1-1.21.2-1.2-1.21.2-1.21.2-1.2-1.31.21.2-1.31.2-1.4-1.51.50.1-1.2
Total locomotion distance, NPP test1.92.63.51.7-1.71.7-1.81.6-1.6-1.71.7-1.61.7-1.6-1.71.61.6-1.91.6-1.7-1.51.80.7-1.4
Locomotion velocity, NPP test1.01.52.01.3-1.21.2-1.31.1-1.2-1.21.2-1.21.2-1.1-1.31.11.1-1.41.2-1.3-1.21.40.2-1.3
Intraocular pressure8.311.614.83.8-3.83.8-3.73.4-3.5-3.43.4-3.43.5-3.3-3.53.43.3-3.73.4-3.4-2.92.93.4-2.0
Delta distance traveled before/after self-admin0.10.11.1-0.40.4-0.40.3-0.40.20.2-0.20.3-0.20.20.2-0.2-0.20.2-0.20.1-0.10.2-1.00.4
Delta ambulatory time before/after self-admin0.00.10.6-0.20.2-0.20.2-0.20.10.2-0.20.2-0.20.10.1-0.1-0.10.1-0.20.10.00.1-0.80.1
Parametrial fat weight1.52.93.71.5-1.51.6-1.61.9-1.6-1.91.9-1.71.9-1.9-1.81.91.9-1.61.8-1.8-1.91.90.6-0.7
Pavlov. Cond. lever latency0.00.10.4-0.00.0-0.00.00.2-0.1-0.20.2-0.20.2-0.2-0.00.30.20.10.2-0.1-0.2-0.00.50.6
Pavlov. Cond. magazine entry latency0.10.11.20.0-0.00.0-0.1-0.10.00.0-0.0-0.0-0.00.0-0.1-0.0-0.0-0.20.1-0.1-0.20.4-0.9-1.1
Pavlov. Cond. change in total contacts0.10.10.7-0.20.2-0.20.2-0.40.30.3-0.30.3-0.30.40.2-0.4-0.40.1-0.30.30.4-0.2-0.4-0.8
Pavlov. Cond. index score0.20.20.5-0.40.4-0.40.4-0.60.50.5-0.50.5-0.50.60.4-0.6-0.60.3-0.50.50.6-0.4-0.7-0.4
Pavlov. Cond. latency score0.20.20.6-0.30.3-0.30.3-0.50.40.5-0.50.5-0.50.50.4-0.6-0.50.2-0.40.40.5-0.3-0.8-0.6
Pavlov. Cond. lever contacts0.10.20.70.5-0.50.5-0.50.3-0.3-0.30.3-0.30.3-0.3-0.40.20.3-0.60.3-0.3-0.10.4-0.1-0.8
Pavlov. Cond. magazine entry number0.00.00.7-0.00.0-0.00.00.10.00.0-0.00.0-0.0-0.10.10.10.10.1-0.10.00.0-0.20.50.8
Pavlov. Cond. intertrial magazine entries0.60.71.80.7-0.70.7-0.80.7-0.8-0.80.8-0.90.8-0.7-0.80.60.7-0.80.9-1.1-1.30.80.2-0.9
Pavlov. Cond. lever-magazine prob. diff.0.50.61.2-0.70.8-0.80.7-0.90.80.9-0.90.8-0.90.90.7-0.9-0.90.7-0.80.70.7-0.6-1.1-0.5
Pavlov. Cond. response bias0.10.11.10.2-0.20.2-0.20.0-0.1-0.10.1-0.10.1-0.1-0.20.00.1-0.30.2-0.2-0.20.4-0.7-1.1
Pavlov. Cond. lever latency0.00.00.0-0.20.2-0.20.2-0.0-0.00.1-0.1-0.1-0.10.00.1-0.0-0.00.20.1-0.0-0.20.0-0.10.0
Pavlov. Cond. magazine entry latency0.60.71.3-0.70.7-0.70.7-0.90.90.9-0.90.9-0.90.90.8-0.9-0.90.7-1.00.91.1-0.8-0.60.2
Pavlov. Cond. change in total contacts1.41.92.5-1.21.2-1.21.2-1.51.51.4-1.41.5-1.41.51.3-1.5-1.61.1-1.51.41.6-1.2-1.5-0.0
Pavlov. Cond. index score0.40.51.2-0.50.5-0.50.6-0.80.80.7-0.70.8-0.70.80.7-0.8-0.80.5-0.80.81.1-0.7-0.50.2
Pavlov. Cond. latency score0.50.61.2-0.60.6-0.60.6-0.80.80.8-0.80.9-0.70.80.7-0.8-0.80.6-0.90.81.1-0.7-0.70.2
Pavlov. Cond. lever contacts0.10.10.30.5-0.50.5-0.50.3-0.3-0.40.4-0.30.4-0.3-0.40.30.3-0.60.3-0.3-0.00.40.1-0.4
Pavlov. Cond. magazine entry number1.92.33.51.3-1.31.4-1.41.6-1.6-1.61.6-1.71.6-1.6-1.61.61.6-1.41.7-1.7-1.91.70.7-0.5
Pavlov. Cond. intertrial magazine entries4.05.38.62.0-2.02.1-2.12.3-2.4-2.52.5-2.52.5-2.4-2.32.42.5-2.12.5-2.6-2.92.31.5-1.0
Pavlov. Cond. lever-magazine prob. diff.0.70.91.8-0.70.7-0.80.8-1.01.00.9-0.91.0-0.91.00.9-1.0-1.00.7-1.11.11.4-1.0-0.50.3
Pavlov. Cond. response bias0.00.00.20.3-0.30.3-0.30.1-0.1-0.20.2-0.00.2-0.0-0.20.10.0-0.30.0-0.00.20.10.2-0.4
Time in closed arm before self-admin1.31.42.3-1.11.1-1.11.2-1.11.11.3-1.31.2-1.31.11.3-1.0-1.11.3-1.21.41.5-1.4-0.11.5
Time in closed arm after self-admin0.50.50.9-0.70.7-0.70.7-0.60.70.8-0.80.7-0.80.70.7-0.6-0.70.7-0.70.91.0-0.7-0.90.1
Time in open arm before self-admin1.21.31.8-1.11.1-1.11.1-1.11.21.3-1.31.2-1.31.11.0-1.0-1.01.1-1.21.31.3-1.1-1.3-0.0
Time in open arm after self-admin0.20.31.30.5-0.50.5-0.50.4-0.4-0.50.5-0.40.5-0.4-0.40.40.5-0.40.4-0.6-0.60.21.10.5
Bone: periosteal estimation11.423.625.7-5.15.1-5.05.1-5.05.15.0-5.05.0-5.05.05.0-5.0-5.05.0-5.05.04.8-4.6-3.72.9
Bone: periosteal perimeter10.116.919.2-4.44.4-4.44.3-4.34.34.2-4.24.2-4.24.24.2-4.2-4.24.2-4.24.23.9-3.6-3.81.9
Bone: post-yield work7.29.811.9-3.33.3-3.33.3-3.13.13.2-3.23.2-3.23.13.3-3.1-3.13.4-3.23.43.2-3.2-1.52.6
Progressive ratio test 1 active lever presses3.03.13.92.0-2.02.0-1.92.0-1.8-1.71.7-1.81.7-1.9-1.81.91.9-1.91.7-1.6-1.31.51.90.2
Progressive ratio test 1 breakpoint2.62.73.51.9-1.91.9-1.81.9-1.7-1.61.6-1.71.6-1.8-1.71.81.8-1.71.6-1.4-1.21.41.80.3
Progressive ratio test 1 inactive lever presses2.42.63.81.7-1.71.7-1.71.9-1.7-1.51.5-1.71.5-1.9-1.71.91.9-1.61.6-1.4-1.21.31.70.7
Progressive ratio test 2 active lever presses1.41.52.51.4-1.41.4-1.31.5-1.2-1.21.2-1.21.2-1.3-1.31.31.3-1.21.2-1.0-0.80.91.60.1
Progressive ratio test 2 breakpoint1.92.23.51.7-1.71.7-1.61.7-1.4-1.51.5-1.51.5-1.6-1.51.51.5-1.51.4-1.2-1.01.11.9-0.0
Progressive ratio test 2 inactive lever presses2.42.73.41.8-1.81.8-1.81.8-1.7-1.71.7-1.81.7-1.7-1.71.61.6-1.71.7-1.5-1.31.41.7-0.7
Incentive Sensitization - Responses0.10.10.2-0.30.3-0.30.3-0.20.30.2-0.20.2-0.20.40.3-0.4-0.40.3-0.20.30.3-0.3-0.1-0.1
Incentive Sensitization - Breakpoint0.00.00.1-0.10.1-0.10.1-0.10.20.0-0.00.1-0.00.20.2-0.2-0.30.2-0.10.20.2-0.20.1-0.2
Sum of active levers in priming session hrs 5-60.20.20.20.4-0.40.4-0.40.4-0.5-0.50.5-0.50.5-0.4-0.40.40.4-0.40.5-0.5-0.40.30.2-0.2
Progressive ratio0.10.10.80.0-0.00.0-0.10.1-0.1-0.00.0-0.0-0.0-0.3-0.20.20.3-0.10.10.00.10.3-0.90.5
Food seeking constrained by brief footshock0.10.10.50.1-0.10.1-0.10.2-0.1-0.10.1-0.10.1-0.3-0.20.30.4-0.10.1-0.2-0.20.2-0.70.6
Seeking ratio, punishment vs. effort0.00.00.1-0.00.0-0.00.1-0.10.10.0-0.00.00.00.20.1-0.1-0.10.1-0.1-0.1-0.1-0.30.3-0.1
Retroperitoneal fat weight0.31.04.40.5-0.50.5-0.60.8-0.9-1.01.0-1.01.0-0.8-0.90.80.8-0.81.0-1.2-1.61.3-0.8-2.1
Reaction time number correct0.50.81.3-0.90.9-0.90.9-1.00.70.9-0.90.8-0.91.11.0-1.1-1.10.9-0.80.70.5-0.9-0.2-0.9
Reaction time mean minus median8.310.912.93.4-3.43.4-3.43.2-3.5-3.43.4-3.43.4-3.3-3.53.33.3-3.63.4-3.4-3.23.61.7-2.7
Reaction time mean minus median AUC6.17.99.42.9-2.92.9-3.02.8-3.0-2.92.9-2.92.8-2.9-3.02.82.9-3.12.9-2.8-2.73.01.5-2.2
Reaction time num false alarms2.02.83.31.6-1.61.7-1.71.7-1.8-1.81.8-1.81.8-1.7-1.71.71.7-1.71.8-1.7-1.71.81.1-0.7
Reaction time num false alarms AUC3.24.35.42.1-2.12.1-2.12.1-2.3-2.22.2-2.22.2-2.1-2.22.12.0-2.22.2-2.2-2.12.31.0-1.7
Reaction time trials correct on left0.50.81.3-0.90.9-0.90.9-1.00.70.9-0.90.8-0.91.11.0-1.1-1.10.9-0.80.70.5-0.9-0.2-0.9
Reaction time trials on left0.40.51.1-0.70.7-0.70.7-0.90.50.7-0.70.7-0.70.90.8-0.9-1.00.7-0.70.50.3-0.7-0.1-1.0
Reaction time mean0.50.71.10.9-0.90.9-0.90.7-0.8-0.90.9-0.80.9-0.8-0.90.60.8-1.00.8-0.9-0.80.90.4-1.0
Reaction time mean AUC0.30.51.30.7-0.70.7-0.70.5-0.6-0.80.8-0.60.8-0.5-0.70.40.6-0.80.6-0.7-0.70.80.2-1.1
Median of all reaction times0.00.10.2-0.10.1-0.10.1-0.30.30.2-0.20.3-0.20.30.2-0.4-0.20.0-0.30.20.4-0.2-0.3-0.5
Reaction time omissions9.512.914.33.7-3.73.7-3.83.7-3.8-3.73.7-3.73.7-3.7-3.83.63.7-3.83.7-3.7-3.53.62.5-2.6
Reaction time false alarm rate2.43.44.51.8-1.81.8-1.91.9-1.9-2.02.0-1.92.0-2.0-2.02.02.0-1.91.9-1.8-1.72.10.8-0.5
Reaction time premature initiation rate4.66.18.02.5-2.52.5-2.52.7-2.6-2.52.5-2.62.5-2.7-2.52.82.6-2.32.6-2.3-2.22.12.7-0.3
Reaction time premature initiations2.83.96.22.0-2.02.0-2.02.1-2.1-2.02.0-2.12.0-2.0-1.92.22.0-1.82.0-1.9-1.91.62.5-0.8
Std. dev. reaction times5.88.29.93.0-3.03.0-3.02.8-3.0-2.92.9-2.92.9-2.9-3.12.83.0-3.22.9-2.9-2.73.01.6-2.2
Reaction time trials completed0.40.51.1-0.70.7-0.70.7-0.90.50.7-0.70.7-0.70.90.8-0.9-1.00.7-0.70.50.3-0.7-0.1-1.0
Reaction time trials AUC0.71.11.6-1.11.1-1.11.1-1.20.81.1-1.11.0-1.01.31.1-1.2-1.31.1-1.00.80.7-1.1-0.3-0.7
Run reversals in cocaine runway, females0.30.33.50.4-0.40.4-0.30.2-0.4-0.30.3-0.30.3-0.1-0.20.10.0-0.30.3-0.2-0.10.10.8-1.9
Run reversals in cocaine runway, males1.31.21.71.1-1.11.1-1.11.2-1.1-1.11.1-1.21.1-1.3-1.11.11.3-1.01.2-1.2-1.11.11.10.5
Latency to leave start box in cocaine runway0.00.00.00.1-0.10.1-0.10.1-0.1-0.10.1-0.10.1-0.2-0.10.10.2-0.10.1-0.00.0-0.10.00.2
Latency to leave start box in cocaine runway, F1.71.82.31.5-1.51.5-1.41.5-1.4-1.31.3-1.41.3-1.5-1.41.51.5-1.31.3-1.2-0.91.01.50.4
Latency to leave start box in cocaine runway, M1.81.72.2-1.51.5-1.51.4-1.51.31.3-1.31.3-1.31.41.4-1.4-1.41.4-1.31.31.0-1.1-1.5-0.2
Std. dev. time between licks in bursts0.81.01.91.2-1.21.1-1.11.1-1.0-1.01.0-1.01.0-1.0-1.01.01.0-1.00.9-0.8-0.50.71.40.1
Total sessions with >9 infusions0.20.30.40.6-0.60.6-0.60.6-0.5-0.60.6-0.50.6-0.5-0.60.50.5-0.60.5-0.3-0.20.40.10.3
Short access day 1 total inactive lever presses0.80.91.21.0-1.01.0-1.01.0-1.0-1.11.1-1.01.1-1.0-1.01.01.0-1.01.0-0.8-0.70.80.7-0.3
Short access day 10 total inactive lever presses0.50.52.80.8-0.80.8-0.70.8-0.7-0.70.7-0.70.7-0.7-0.60.70.7-0.50.7-0.6-0.40.31.70.2
Short access day 1 total infusions0.10.10.3-0.20.2-0.20.2-0.20.30.1-0.10.2-0.10.10.2-0.2-0.10.2-0.20.30.3-0.2-0.50.5
Short access day 10 total infusions0.50.50.80.7-0.70.7-0.80.7-0.8-0.70.7-0.80.7-0.7-0.80.50.7-0.80.8-0.8-0.80.90.1-0.7
Short access total infusions0.10.10.20.4-0.40.4-0.40.3-0.3-0.30.3-0.30.3-0.4-0.40.30.4-0.40.3-0.2-0.10.40.10.3
Short access day 1 locomotion0.10.11.8-0.10.1-0.10.10.00.30.3-0.30.3-0.30.00.2-0.00.00.2-0.30.40.6-0.40.11.3
Short access day 10 total locomotion0.50.66.00.5-0.50.5-0.30.5-0.2-0.40.4-0.20.4-0.5-0.20.30.6-0.10.20.00.4-0.41.82.4
Short access total locomotion0.30.43.40.5-0.50.5-0.40.5-0.3-0.30.3-0.30.3-0.5-0.30.40.6-0.20.20.10.4-0.11.31.8
One hour access (0.3 mA shock)0.10.21.10.4-0.40.4-0.40.4-0.4-0.30.3-0.40.3-0.3-0.40.20.2-0.40.4-0.3-0.20.5-0.0-1.0
Compulsive drug intake0.60.61.1-0.80.8-0.80.8-0.80.80.8-0.80.8-0.80.90.7-0.6-0.90.7-0.80.60.5-0.6-1.00.3
One hour access (shock baseline)0.00.00.20.1-0.10.1-0.10.1-0.1-0.00.0-0.00.0-0.1-0.1-0.20.1-0.10.00.10.20.1-0.1-0.4
Social response proportion0.20.30.50.6-0.60.6-0.60.4-0.6-0.60.6-0.50.6-0.4-0.50.40.3-0.60.5-0.5-0.20.70.1-0.7
Social responses7.710.011.23.3-3.33.3-3.33.2-3.3-3.33.3-3.33.3-3.2-3.23.33.2-3.23.3-3.0-2.73.03.0-1.6
Social time0.40.54.10.6-0.60.6-0.60.2-0.5-0.50.5-0.30.5-0.1-0.50.20.0-0.80.4-0.5-0.30.9-1.1-2.0
Soleus weight0.72.03.0-1.61.6-1.61.6-1.41.41.3-1.31.4-1.31.31.5-1.4-1.31.7-1.41.51.2-1.4-0.91.1
Bone: stiffness15.524.427.4-5.15.1-5.15.1-5.15.15.2-5.25.1-5.25.15.0-5.1-5.15.0-5.15.14.9-4.5-4.22.6
Tibialis anterior weight1.96.68.9-2.82.8-2.82.8-2.42.72.6-2.62.5-2.62.42.7-2.5-2.43.0-2.52.82.5-2.7-1.22.3
Time to tail flick, vehicle, before self-admin1.21.22.01.1-1.11.1-1.21.3-1.2-0.90.9-1.10.9-1.2-1.21.41.2-1.21.1-1.1-1.11.30.50.1
Time to tail flick, vehicle, after self-admin0.20.20.7-0.20.2-0.20.3-0.30.30.4-0.40.3-0.40.40.5-0.4-0.50.4-0.40.60.8-0.80.60.4
Time to tail flick, test, before self-admin0.70.73.60.8-0.80.8-0.80.6-0.7-0.90.9-0.70.9-0.6-0.70.60.6-0.80.7-0.9-0.90.60.5-1.9
Time to tail flick, test, after self-admin0.10.20.6-0.40.4-0.40.4-0.40.30.3-0.30.2-0.30.40.4-0.5-0.40.4-0.20.20.1-0.4-0.6-0.8
Delta time to tail flick, vehicle, before/after SA0.40.40.8-0.60.6-0.60.6-0.80.60.5-0.50.6-0.50.80.7-0.9-0.80.6-0.70.70.8-0.9-0.10.1
Delta time to tail flick, test, before/after SA0.50.52.4-0.60.6-0.60.6-0.50.60.8-0.80.5-0.80.40.5-0.5-0.30.6-0.50.70.7-0.5-0.71.6
Tibia length7.019.724.3-4.34.3-4.34.4-4.64.64.7-4.74.6-4.74.64.5-4.6-4.64.3-4.64.74.9-4.4-3.42.8
Ambulatory time before self-admin3.53.65.52.1-2.12.1-2.02.1-1.9-1.91.9-2.01.9-2.0-1.91.92.0-1.92.0-1.8-1.61.52.40.2
Ambulatory time after self-admin1.41.62.81.3-1.31.3-1.31.3-1.2-1.21.2-1.31.2-1.3-1.21.31.3-1.21.3-1.2-1.11.01.70.7
Bone: tissue strength0.50.51.0-0.60.6-0.60.6-0.70.70.8-0.80.9-0.90.70.7-0.7-0.70.6-0.90.81.0-0.8-0.30.5
Total heroin consumption2.53.04.6-1.61.6-1.61.7-1.51.81.9-1.91.8-1.91.61.8-1.5-1.71.9-1.82.02.1-2.1-0.00.9
Bone: trabecular number4.97.717.5-2.82.8-2.82.7-3.02.83.0-3.02.9-3.02.92.6-2.9-2.92.4-2.72.62.4-1.8-4.2-0.0
Bone: trabecular spacing1.72.38.21.4-1.41.4-1.31.6-1.5-1.61.6-1.51.7-1.6-1.21.61.6-1.11.4-1.3-1.30.72.90.6
Bone: trabecular thickness0.10.20.50.5-0.50.4-0.50.3-0.3-0.10.1-0.20.1-0.3-0.50.30.3-0.70.3-0.3-0.00.7-0.7-0.6
Bone: trabecular tissue density0.10.21.40.4-0.40.4-0.40.4-0.2-0.20.2-0.20.2-0.3-0.30.30.3-0.30.1-0.10.2-0.11.20.6
Water consumed over 24 hours0.00.10.4-0.30.3-0.30.2-0.00.10.2-0.20.1-0.20.00.10.1-0.00.2-0.10.1-0.00.2-0.60.5
Number of responses in last shaping day0.60.63.2-0.60.6-0.60.6-0.40.80.7-0.70.7-0.70.40.6-0.5-0.40.7-0.71.01.2-0.90.11.8