Hub : Genes

Habp2

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Liver isoform ratio XM_006231633.4 0.72 0.19 0.0e+00 0.22 0.1 0.21 0.21 3.4e-24 4.6e-11 1.7e-22 5.9e-23
2 Liver isoform ratio NM_001001505.2 0.72 0.16 0.0e+00 0.22 0.09 0.2 0.2 8.1e-24 3.2e-10 3.8e-22 1.5e-21
3 Liver intron excision ratio chr1_255327227_255336618 0.74 0.16 0.0e+00 0.42 0.24 0.43 0.42 1.8e-50 5.9e-27 1.4e-51 4.4e-51
4 Liver mRNA stability Habp2 0.64 0.11 0.0e+00 0.46 0.3 0.47 0.47 1.8e-57 1.1e-33 2.6e-58 1.6e-58
5 Liver intron excision ratio chr1_255336728_255338715 0.63 0.15 0.0e+00 0.4 0.26 0.41 0.41 7.1e-48 5.8e-29 3.3e-48 1.6e-48
6 Liver gene expression Habp2 0.87 0.07 0.0e+00 0.57 0.42 0.58 0.58 1.0e-76 8.6e-51 2.8e-78 3.0e-78
7 Liver alternative TSS NM_001001505.2 0.02 0.01 8.0e-03 0 -0 -0 -0 8.6e-02 7.2e-01 6.7e-01 4.5e-01
8 Liver alternative TSS XM_006231633.4 0.02 0.01 6.1e-03 0.01 -0 0 0 5.4e-02 9.8e-01 3.4e-01 1.9e-01
9 Liver intron excision ratio chr1_255347905_255349535 0.06 0.03 1.0e-04 0.03 0.04 0.03 0.03 9.4e-05 2.6e-05 2.2e-04 3.0e-04

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9
Bone: apparent density1.62.85.01.9-1.9-1.8-1.8-1.91.50.4-0.4-2.2
Area under the delay curve0.80.91.31.0-1.0-1.0-1.0-1.00.9-0.50.5-1.1
BMI with tail9.229.840.26.3-6.3-6.3-6.2-6.36.1-3.53.5-2.7
BMI without tail4.18.511.53.4-3.4-3.4-3.4-3.43.3-1.71.7-1.8
Body weight11.146.362.87.9-7.9-7.9-7.8-7.97.7-4.34.3-3.2
Weight adjusted by age6.57.49.33.0-3.0-3.0-3.0-3.03.0-2.32.3-0.8
Bone surface0.81.52.11.5-1.5-1.4-1.4-1.51.2-0.00.0-1.2
Bone volume2.84.86.82.6-2.6-2.6-2.5-2.62.3-0.50.5-2.0
Breakpoint value in progressive ratio session0.30.41.50.6-0.6-0.5-0.5-0.50.40.3-0.3-1.2
Number of licking bursts0.80.92.01.1-1.1-1.0-1.0-1.00.90.0-0.0-1.4
Context. condit. distance diff. score0.30.41.5-0.50.50.50.50.5-0.50.5-0.51.2
Locomotion velocity, session 11.31.41.9-1.41.41.41.41.4-1.30.8-0.80.1
Locomotion distance, session 10.30.41.7-0.50.50.50.60.5-0.4-0.10.11.3
Locomotion velocity, session 20.60.73.7-0.40.40.30.30.4-0.1-0.90.91.9
Locomotion distance, session 21.21.63.51.1-1.1-1.1-1.1-1.11.2-1.91.90.4
Locomotion velocity, session 30.30.31.30.2-0.2-0.2-0.2-0.20.3-0.80.81.2
Locomotion distance, session 30.60.72.70.2-0.2-0.2-0.2-0.20.4-1.21.21.6
Stereotopy head waving bouts, day 30.00.10.2-0.00.00.10.10.1-0.0-0.50.5-0.3
Stereotopy head waving duration, day 30.40.50.6-0.80.80.80.80.8-0.80.5-0.5-0.5
Locomotion velocity, session 70.20.20.40.6-0.6-0.6-0.6-0.60.5-0.10.1-0.4
Locomotion distance, session 70.00.00.30.0-0.0-0.0-0.0-0.00.0-0.20.20.5
Stereotopy head waving bouts, day 70.10.10.20.3-0.3-0.3-0.3-0.30.3-0.10.1-0.4
Stereotopy head waving duration, day 70.50.71.00.9-0.9-0.9-0.9-0.90.9-0.30.3-1.0
Locomotion velocity, session 81.51.82.1-1.31.31.31.41.3-1.41.4-1.41.1
Locomotion distance, session 80.30.42.6-0.30.30.30.50.4-0.30.0-0.01.6
Degree of sensitization distance0.70.71.6-0.50.50.60.50.5-0.71.3-1.3-1.1
Degree of sensitization stereotypy0.10.10.40.3-0.3-0.3-0.3-0.30.20.3-0.3-0.6
Conditioned locomotion0.10.10.2-0.30.30.40.40.4-0.3-0.30.30.5
Cocaine response after cond. corrected2.62.94.2-2.02.01.91.91.9-1.7-0.10.12.1
Cocaine response after cond. not corrected3.03.34.5-2.12.12.12.12.1-1.90.4-0.41.8
Cocaine response before conditioning0.30.41.2-0.10.10.10.10.1-0.21.1-1.1-0.9
Saline control response0.10.10.6-0.00.00.10.10.2-0.0-0.30.30.8
Bone: connectivity density0.20.20.80.1-0.1-0.1-0.1-0.2-0.10.9-0.9-0.7
Bone: cortical apparent density1.11.58.1-0.60.60.60.60.6-0.3-1.21.22.8
Bone: cortical area10.215.420.04.5-4.5-4.4-4.4-4.44.3-2.72.7-2.7
Bone: cortical porosity0.20.21.00.4-0.4-0.4-0.4-0.40.20.2-0.2-1.0
Bone: cortical porosity0.50.51.80.7-0.7-0.7-0.7-0.70.50.3-0.3-1.3
Bone: cortical thickness5.38.710.83.3-3.3-3.3-3.3-3.23.3-2.52.5-1.4
Bone: cortical thickness3.54.14.72.2-2.2-2.2-2.1-2.12.2-2.12.1-0.1
Bone: cortical tissue density1.21.68.6-0.80.80.80.70.8-0.5-1.11.12.9
Condit. Reinf. active minus inactive responses0.10.10.2-0.50.50.50.40.5-0.4-0.20.20.2
Condit. Reinf. active-inactive response ratio0.20.20.3-0.50.50.50.50.5-0.50.6-0.60.1
Condit. Reinf. active responses0.10.20.50.2-0.2-0.2-0.3-0.20.3-0.70.7-0.6
Condit. Reinf. inactive responses0.40.51.40.5-0.5-0.5-0.6-0.50.6-0.90.9-1.2
Incentive salience index mean0.50.60.9-0.90.90.90.91.0-0.80.0-0.00.5
Condit. Reinf. lever presses0.50.61.0-1.01.00.90.91.0-0.90.2-0.20.3
Condit. Reinf. active minus inactive responses0.70.96.20.3-0.3-0.3-0.4-0.40.20.8-0.8-2.5
Condit. Reinf. active-inactive response ratio0.60.62.2-0.30.30.40.30.3-0.41.1-1.1-1.5
Condit. Reinf. active responses1.52.09.31.2-1.2-1.2-1.3-1.31.10.3-0.3-3.1
Condit. Reinf. inactive responses1.21.53.11.3-1.3-1.3-1.4-1.31.2-0.40.4-1.8
Condit. Reinf. lever presses0.50.63.40.6-0.6-0.6-0.7-0.60.50.3-0.3-1.8
Condit. Reinf. lever reinforcers received1.01.47.60.9-0.9-0.9-1.0-1.00.80.4-0.4-2.8
Conditioned reinforcement - actives0.40.41.1-0.40.40.40.30.4-0.3-1.01.00.9
Conditioned reinforcement - inactives0.60.71.00.9-0.9-0.9-1.0-0.90.8-0.70.7-0.5
Conditioned locomotion0.40.51.4-0.60.60.60.60.6-0.5-0.70.71.2
Patch foraging indifference point 0 sec3.55.77.42.7-2.7-2.7-2.7-2.72.6-1.31.3-2.0
Patch foraging indifference point AUC0.30.42.60.2-0.2-0.2-0.2-0.30.10.4-0.4-1.6
Delay disc. indifference point, 0s delay1.01.11.51.1-1.1-1.0-1.1-1.01.0-1.21.2-0.4
Delay disc. indifference point, 16s delay0.10.10.60.3-0.3-0.3-0.2-0.30.10.4-0.4-0.8
Delay disc. indifference point, 2s delay0.10.10.10.2-0.2-0.2-0.3-0.20.2-0.30.30.1
Delay disc. indifference point, 24s delay1.01.03.60.9-0.9-0.9-0.9-0.90.70.5-0.5-1.9
Delay disc. indifference point, 4s delay0.00.00.2-0.10.10.10.20.1-0.20.2-0.2-0.4
Delay disc. indifference point, 8s delay2.82.93.61.9-1.9-1.9-1.9-1.91.8-1.11.1-1.7
Indifference point function ln k0.10.10.7-0.10.10.20.10.2-0.0-0.20.20.9
Indifference point function log k0.10.10.7-0.10.10.20.10.2-0.0-0.20.20.9
Patch foraging total patch changes 0 sec3.55.67.22.7-2.7-2.7-2.7-2.62.6-1.21.2-2.2
Patch foraging total patch changes 12 sec1.21.64.31.3-1.3-1.3-1.3-1.31.10.2-0.2-2.1
Patch foraging total patch changes 18 sec2.32.97.71.8-1.8-1.8-1.7-1.81.6-0.20.2-2.8
Patch foraging total patch changes 24 sec1.92.37.41.5-1.5-1.5-1.5-1.51.30.2-0.2-2.7
Patch foraging total patch changes 6 sec4.76.99.13.0-3.0-3.0-2.9-3.02.8-1.31.3-2.7
Patch foraging time to switch 0 sec0.20.30.8-0.50.50.50.50.5-0.50.4-0.40.9
Patch foraging water rate 0 sec0.30.50.60.7-0.7-0.7-0.7-0.70.8-0.70.7-0.6
Patch foraging water rate 12 sec0.71.12.91.1-1.1-1.0-1.0-1.01.00.4-0.4-1.7
Patch foraging water rate 18 sec0.60.91.01.0-1.0-1.0-1.0-1.01.0-0.90.90.0
Patch foraging water rate 24 sec1.52.02.51.6-1.6-1.5-1.5-1.51.5-1.41.4-0.2
Patch foraging water rate 6 sec0.30.51.10.6-0.6-0.5-0.5-0.50.7-1.11.10.4
Seeking ratio, delayed vs. immediate footshock0.10.10.2-0.30.30.20.20.3-0.30.1-0.10.5
Distance traveled before self-admin0.40.42.2-0.50.50.40.40.4-0.2-0.40.41.5
Distance traveled after self-admin0.91.02.20.8-0.8-0.9-0.8-0.81.0-1.21.21.5
Extensor digitorum longus weight0.41.82.41.6-1.6-1.5-1.5-1.51.30.1-0.1-1.5
Bone: elastic displacement0.00.00.2-0.10.10.10.10.1-0.20.3-0.3-0.4
Bone: elastic work1.41.82.31.4-1.4-1.4-1.4-1.41.4-1.51.50.4
Bone: endosteal estimation1.94.25.62.4-2.4-2.4-2.3-2.32.2-1.31.3-1.5
Bone: endosteal perimeter5.511.314.53.8-3.8-3.8-3.7-3.83.7-2.62.6-1.7
Epididymis fat weight16.939.551.97.2-7.2-7.2-7.2-7.27.0-4.14.1-3.8
Delta time in closed arm before/after self-admin0.30.20.5-0.40.40.40.30.4-0.2-0.70.70.7
Delta time in open arm before/after self-admin0.30.31.10.4-0.4-0.4-0.4-0.40.30.5-0.5-1.1
Diff in mean of infusions in LGA sessions3.33.74.4-2.02.02.02.02.0-2.12.1-2.10.0
Delay discount exponential model param1.01.01.5-1.11.11.11.11.1-1.00.5-0.51.2
Extinction: sum of active levers before priming0.40.40.5-0.70.70.60.60.6-0.70.7-0.7-0.6
Active lever presses in extinction session 60.50.50.80.8-0.8-0.8-0.9-0.80.8-0.40.4-0.4
Bone: final force3.35.46.92.6-2.6-2.6-2.6-2.52.5-1.91.9-0.9
Bone: final moment3.76.07.72.8-2.8-2.8-2.7-2.72.7-2.02.0-1.1
Food consumed during 24 hour testing period0.00.00.20.0-0.00.10.10.10.0-0.10.10.4
Glucose6.49.612.13.4-3.4-3.4-3.4-3.43.5-2.82.8-0.9
Heart weight2.73.85.22.2-2.2-2.2-2.2-2.12.3-1.51.5-0.9
Delay discount hyperbolic model param0.60.70.9-0.90.90.90.90.9-0.80.4-0.40.9
Intermittent access intake day 1-15 change2.72.63.61.8-1.8-1.8-1.9-1.91.8-1.11.1-1.0
Intermittent access intake escalation4.64.55.42.2-2.2-2.3-2.3-2.32.3-2.22.2-0.2
Intermittent access intake escalation 22.72.63.81.7-1.7-1.6-1.6-1.61.7-1.91.90.3
Intermitt. access day 1 inactive lever presses2.12.23.21.8-1.8-1.7-1.7-1.71.5-0.10.1-1.7
Intermitt. access day 15 inactive lever presses0.10.10.20.5-0.5-0.4-0.4-0.40.4-0.30.3-0.2
Intermitt. access escalation Index0.10.10.20.4-0.4-0.4-0.4-0.40.4-0.20.20.3
Intermittent access day 1 total infusions0.20.20.40.3-0.3-0.4-0.4-0.40.3-0.70.7-0.3
Intermittent access day 15 total infusions2.12.32.81.5-1.5-1.6-1.7-1.61.5-1.71.7-0.4
Intermittent access terminal intake (last 3 days)1.01.11.51.0-1.0-1.1-1.1-1.11.0-1.21.2-0.3
Intermittent access total infusions1.01.11.81.0-1.0-1.0-1.1-1.11.0-1.31.3-0.5
Intermittent access day 1 locomotion0.20.20.60.0-0.0-0.1-0.1-0.10.1-0.70.70.8
Intermittent access day 15 total locomotion2.42.63.41.7-1.7-1.8-1.8-1.91.7-1.21.2-0.9
Intermittent access total locomotion0.60.61.70.5-0.5-0.5-0.6-0.50.6-1.31.30.8
Intermittent access standard deviation1.11.23.11.2-1.2-1.1-1.2-1.10.9-0.30.3-1.8
Left kidney weight4.713.418.43.7-3.7-3.7-3.6-3.63.8-4.34.31.6
Right kidney weight6.819.022.84.6-4.6-4.6-4.6-4.54.8-4.64.60.6
Cocaine induced anxiety4.65.37.5-2.42.42.62.62.7-2.41.4-1.42.4
Post-drug Anxiety0.80.91.6-0.90.91.11.11.2-0.90.3-0.31.3
Baseline Anxiety6.36.78.92.9-2.9-2.9-2.9-3.02.8-1.51.5-2.4
Tail length0.51.41.81.3-1.3-1.3-1.3-1.31.3-0.70.7-0.9
Length with tail3.211.615.64.0-4.0-3.9-3.9-3.93.8-2.42.4-1.3
Length without tail6.213.617.94.2-4.2-4.2-4.2-4.24.1-2.82.8-1.2
Times rat made contact with spout0.70.81.10.9-0.9-0.9-0.9-0.90.9-1.11.1-0.0
Lifetime Intake1.11.32.01.1-1.1-1.1-1.2-1.11.1-1.41.4-0.4
Liver weight, left4.57.19.33.1-3.1-3.0-3.0-3.12.8-1.51.5-2.3
Liver weight, right8.714.518.54.3-4.3-4.3-4.3-4.34.2-2.92.9-2.0
Locomotor activity2.03.23.91.9-1.9-1.9-2.0-1.82.0-1.91.90.1
Locomotor testing distance2.43.96.91.8-1.8-1.9-1.9-1.82.1-2.62.60.8
Locomotor testing rearing1.62.53.21.7-1.7-1.7-1.7-1.61.8-1.61.60.3
Locomotion in novel chamber0.30.31.70.1-0.1-0.2-0.2-0.10.3-0.80.81.3
Locomotion in novel chamber post-restriction1.41.72.9-1.51.51.51.41.5-1.3-0.20.21.7
Fecal boli incidents, locomotor time 10.20.31.10.2-0.2-0.3-0.3-0.30.4-0.60.6-1.0
Change in fecal boli incidents, locomotor task0.90.91.8-0.80.80.80.80.8-0.91.3-1.30.5
Time >=10cm from walls, locomotor time 12.52.53.1-1.71.71.71.71.7-1.81.5-1.50.6
Bouts of movement, locomotor time 10.80.93.30.9-0.9-0.9-0.9-0.90.70.3-0.3-1.8
Total resting periods, locomotor time 10.70.82.30.9-0.9-0.9-0.9-0.90.80.1-0.1-1.5
Rest time, locomotor task time 10.30.31.10.3-0.3-0.3-0.3-0.30.4-1.11.10.4
Distance moved, locomotor task time 10.10.10.30.2-0.2-0.2-0.2-0.20.10.6-0.6-0.3
Vertical activity count, locomotor time 10.40.41.0-0.60.60.60.50.6-0.60.5-0.51.0
Time >=10cm from walls, locomotor time 20.30.30.90.3-0.3-0.3-0.4-0.30.20.7-0.7-1.0
Bouts of movement, locomotor time 21.11.22.2-0.90.91.01.11.0-1.21.5-1.50.7
Total resting periods, locomotor time 20.50.61.2-0.50.50.60.70.7-0.81.1-1.10.6
Rest time, locomotor task time 20.20.20.50.2-0.2-0.4-0.3-0.40.4-0.70.70.6
Distance moved, locomotor task time 20.20.21.30.3-0.3-0.2-0.3-0.20.10.4-0.4-1.1
Vertical activity count, locomotor time 20.20.20.60.5-0.5-0.3-0.4-0.40.3-0.10.1-0.8
Light reinforcement 11.22.22.8-1.71.71.71.61.6-1.61.1-1.10.8
Light reinforcement 21.72.33.3-1.81.81.71.71.7-1.70.7-0.71.2
Bone: marrow area2.04.45.82.4-2.4-2.4-2.3-2.42.2-1.41.4-1.5
Bone: maximum diameter8.816.220.94.6-4.6-4.6-4.5-4.54.4-2.52.5-3.2
Bone: maximum force3.25.57.12.7-2.7-2.7-2.6-2.62.6-1.91.9-0.8
Bone: maximum moment3.56.07.82.8-2.8-2.8-2.7-2.72.7-2.02.0-1.0
Mean time between licks in bursts0.10.10.80.1-0.10.0-0.00.0-0.10.4-0.4-0.9
Mean num. licks in bursts0.50.62.1-0.10.10.00.00.00.1-1.31.31.4
Cd content in liver3.94.35.0-2.22.22.22.22.1-2.22.2-2.20.3
Co content in liver0.50.60.8-0.90.90.80.80.8-0.70.5-0.50.9
Cu content in liver0.00.00.10.1-0.1-0.2-0.2-0.20.1-0.10.10.4
Fe content in liver0.10.10.1-0.30.30.30.30.3-0.20.1-0.1-0.3
K content in liver0.40.41.2-0.50.50.50.50.5-0.61.1-1.1-0.0
Mg content in liver0.40.41.5-0.10.10.20.20.1-0.31.2-1.2-0.9
Mn content in liver0.30.40.6-0.70.70.50.60.5-0.60.7-0.70.7
Na content in liver0.60.61.7-0.50.50.50.50.5-0.71.3-1.3-0.6
Rb content in liver1.72.12.8-1.71.71.71.61.6-1.61.2-1.2-0.5
Se content in liver0.30.41.0-0.60.60.50.50.5-0.61.0-1.0-0.1
Sr content in liver2.32.12.9-1.51.51.51.51.5-1.51.1-1.11.7
Zn content in liver2.02.23.0-1.51.51.51.51.5-1.51.3-1.31.7
Bone: minimum diameter4.07.49.83.1-3.1-3.1-3.1-3.13.0-1.61.6-2.2
Time in familiar zone, hab. session 10.20.20.7-0.40.40.40.40.4-0.30.2-0.20.8
Time in novel zone, hab. session 10.90.92.01.0-1.0-1.0-1.0-1.00.9-0.30.3-1.4
Total zone transitions, hab. session 11.52.13.31.4-1.4-1.4-1.4-1.41.5-1.81.80.1
Total locomotion distance, hab. session 10.10.20.8-0.00.00.0-0.00.00.1-0.90.9-0.1
Locomotion velocity, hab. session 10.10.20.6-0.30.30.30.20.3-0.2-0.70.70.1
Time in familiar zone, hab. session 21.01.04.80.8-0.8-0.8-0.8-0.80.60.4-0.4-2.2
Time in novel zone, hab. session 20.50.53.2-0.30.30.30.30.3-0.1-0.80.81.8
Total zone transitions, hab. session 21.72.12.61.5-1.5-1.6-1.6-1.51.6-1.51.5-0.1
Total locomotion distance, hab. session 20.60.81.60.8-0.8-0.8-0.8-0.80.9-1.31.30.0
Locomotion velocity, hab. session 20.50.61.50.6-0.6-0.7-0.7-0.60.8-1.21.20.2
Novel to familiar place preference ratio0.10.10.60.2-0.2-0.2-0.2-0.20.10.5-0.5-0.8
Novelty place preference0.20.20.70.4-0.4-0.4-0.4-0.40.30.3-0.3-0.8
Time in novel zone, NPP test0.60.61.90.7-0.7-0.7-0.8-0.80.70.3-0.3-1.4
Total zone transitions, NPP test0.91.31.71.3-1.3-1.3-1.3-1.31.3-1.01.0-0.3
Total locomotion distance, NPP test0.40.50.70.8-0.8-0.8-0.7-0.70.8-0.80.8-0.3
Locomotion velocity, NPP test0.20.20.70.3-0.3-0.3-0.3-0.30.3-0.80.80.4
Intraocular pressure2.53.56.12.0-2.0-2.0-2.1-2.11.9-0.80.8-2.5
Delta distance traveled before/after self-admin1.61.72.41.5-1.5-1.5-1.6-1.51.5-0.80.80.1
Delta ambulatory time before/after self-admin1.41.52.31.5-1.5-1.5-1.5-1.51.4-0.30.3-0.6
Parametrial fat weight7.915.320.14.4-4.4-4.4-4.5-4.54.3-1.71.7-3.9
Pavlov. Cond. lever latency0.20.30.90.5-0.5-0.5-0.4-0.50.30.5-0.5-1.0
Pavlov. Cond. magazine entry latency0.50.61.40.6-0.6-0.6-0.7-0.60.7-1.21.20.0
Pavlov. Cond. change in total contacts0.00.10.2-0.00.0-0.0-0.10.00.2-0.30.30.5
Pavlov. Cond. index score0.30.40.80.6-0.6-0.6-0.6-0.50.7-0.90.90.3
Pavlov. Cond. latency score0.20.30.60.4-0.4-0.4-0.4-0.30.5-0.80.80.3
Pavlov. Cond. lever contacts0.10.10.2-0.30.30.30.30.4-0.2-0.00.00.3
Pavlov. Cond. magazine entry number1.31.62.4-1.21.21.21.31.2-1.31.6-1.60.0
Pavlov. Cond. intertrial magazine entries0.00.00.0-0.10.10.10.00.1-0.0-0.10.1-0.1
Pavlov. Cond. lever-magazine prob. diff.0.20.30.50.5-0.5-0.5-0.6-0.40.6-0.70.70.1
Pavlov. Cond. response bias0.40.51.30.6-0.6-0.6-0.6-0.50.7-1.21.20.4
Pavlov. Cond. lever latency0.40.64.0-0.30.30.20.30.3-0.1-0.70.72.0
Pavlov. Cond. magazine entry latency1.82.02.71.6-1.6-1.6-1.6-1.61.5-0.80.8-1.3
Pavlov. Cond. change in total contacts0.71.04.50.9-0.9-0.9-0.9-0.90.70.1-0.1-2.1
Pavlov. Cond. index score1.41.83.61.4-1.4-1.4-1.5-1.41.3-0.40.4-1.9
Pavlov. Cond. latency score1.41.73.51.4-1.4-1.4-1.5-1.41.3-0.30.3-1.9
Pavlov. Cond. lever contacts0.50.72.10.8-0.8-0.8-0.8-0.80.7-0.20.2-1.4
Pavlov. Cond. magazine entry number1.51.82.4-1.51.51.51.61.6-1.40.6-0.61.3
Pavlov. Cond. intertrial magazine entries0.00.10.10.2-0.2-0.3-0.3-0.30.30.1-0.1-0.2
Pavlov. Cond. lever-magazine prob. diff.1.31.72.81.4-1.4-1.4-1.5-1.41.3-0.60.6-1.7
Pavlov. Cond. response bias1.11.53.01.3-1.3-1.3-1.3-1.31.1-0.50.5-1.7
Time in closed arm before self-admin0.40.40.70.8-0.8-0.8-0.6-0.80.60.4-0.40.2
Time in closed arm after self-admin0.10.10.4-0.20.20.20.20.2-0.20.2-0.20.7
Time in open arm before self-admin1.31.42.0-1.41.41.41.41.4-1.40.6-0.60.4
Time in open arm after self-admin0.60.70.8-0.80.80.80.80.8-0.90.7-0.7-0.8
Bone: periosteal estimation6.513.517.64.2-4.2-4.2-4.1-4.14.0-2.62.6-2.4
Bone: periosteal perimeter11.218.624.04.9-4.9-4.9-4.8-4.94.8-3.13.1-2.6
Bone: post-yield work0.10.10.60.3-0.3-0.3-0.2-0.30.10.4-0.4-0.8
Progressive ratio test 1 active lever presses1.41.53.41.0-1.0-1.0-1.1-1.01.1-1.91.90.1
Progressive ratio test 1 breakpoint0.60.61.90.5-0.5-0.5-0.6-0.50.5-1.41.4-0.0
Progressive ratio test 1 inactive lever presses0.40.40.70.7-0.7-0.6-0.7-0.60.6-0.90.9-0.1
Progressive ratio test 2 active lever presses3.13.34.21.9-1.9-1.9-2.0-1.91.8-2.12.1-0.3
Progressive ratio test 2 breakpoint2.63.03.61.8-1.8-1.8-1.9-1.81.7-1.91.9-0.4
Progressive ratio test 2 inactive lever presses1.11.31.91.3-1.3-1.3-1.4-1.31.1-0.60.6-1.0
Incentive Sensitization - Responses1.81.82.51.5-1.5-1.6-1.6-1.61.5-1.11.1-0.6
Incentive Sensitization - Breakpoint1.81.82.51.5-1.5-1.6-1.6-1.61.5-1.01.0-0.7
Sum of active levers in priming session hrs 5-62.82.73.3-1.81.81.81.81.8-1.81.6-1.60.3
Progressive ratio0.70.81.2-1.11.11.11.11.1-1.10.4-0.40.0
Food seeking constrained by brief footshock0.50.61.3-0.50.50.50.50.5-0.71.1-1.1-0.9
Seeking ratio, punishment vs. effort0.30.30.50.7-0.7-0.7-0.7-0.70.60.2-0.2-0.3
Retroperitoneal fat weight14.246.761.37.8-7.8-7.8-7.8-7.87.7-4.54.5-3.7
Reaction time number correct0.81.11.51.2-1.2-1.2-1.2-1.21.1-0.30.3-1.2
Reaction time mean minus median0.40.61.40.6-0.6-0.6-0.6-0.50.7-1.21.2-0.1
Reaction time mean minus median AUC1.01.33.20.9-0.9-0.9-0.9-0.81.0-1.81.80.6
Reaction time num false alarms0.00.00.0-0.10.10.10.10.0-0.10.0-0.0-0.1
Reaction time num false alarms AUC0.10.10.30.0-0.0-0.1-0.1-0.20.1-0.50.50.2
Reaction time trials correct on left0.81.11.51.2-1.2-1.2-1.2-1.21.1-0.30.3-1.2
Reaction time trials on left0.81.21.61.3-1.3-1.2-1.2-1.21.1-0.30.3-1.2
Reaction time mean0.30.51.50.3-0.3-0.3-0.4-0.30.5-1.21.20.4
Reaction time mean AUC0.10.20.7-0.10.10.10.00.10.1-0.80.80.4
Median of all reaction times0.30.51.50.2-0.2-0.3-0.3-0.20.5-1.21.20.7
Reaction time omissions0.20.30.40.7-0.7-0.6-0.6-0.60.6-0.00.0-0.6
Reaction time false alarm rate0.20.20.4-0.60.60.60.50.5-0.6-0.00.00.4
Reaction time premature initiation rate0.91.32.70.8-0.8-0.9-0.9-0.91.0-1.61.61.0
Reaction time premature initiations2.02.84.01.7-1.7-1.7-1.7-1.71.7-2.02.00.5
Std. dev. reaction times1.52.13.81.3-1.3-1.4-1.4-1.31.5-1.91.9-0.4
Reaction time trials completed0.81.21.61.3-1.3-1.2-1.2-1.21.1-0.30.3-1.2
Reaction time trials AUC0.81.21.61.3-1.3-1.2-1.2-1.21.1-0.30.3-1.3
Run reversals in cocaine runway, females0.90.91.21.1-1.1-1.0-1.0-1.01.0-0.80.80.3
Run reversals in cocaine runway, males1.51.52.1-1.21.21.21.21.2-1.31.5-1.50.2
Latency to leave start box in cocaine runway0.50.60.7-0.80.80.70.80.8-0.80.7-0.70.7
Latency to leave start box in cocaine runway, F0.91.01.3-1.11.11.01.11.1-1.00.8-0.81.0
Latency to leave start box in cocaine runway, M0.30.30.40.6-0.6-0.6-0.6-0.60.6-0.50.5-0.2
Std. dev. time between licks in bursts0.50.60.8-0.80.80.90.80.9-0.90.5-0.5-0.8
Total sessions with >9 infusions5.25.89.12.4-2.4-2.3-2.4-2.32.5-3.03.00.1
Short access day 1 total inactive lever presses1.01.11.81.3-1.3-1.3-1.2-1.21.1-0.60.6-0.3
Short access day 10 total inactive lever presses0.40.50.80.9-0.9-0.7-0.8-0.70.8-0.30.3-0.7
Short access day 1 total infusions0.90.91.70.9-0.9-0.9-0.9-0.80.9-1.31.30.5
Short access day 10 total infusions0.30.31.40.2-0.2-0.2-0.2-0.20.2-1.21.20.2
Short access total infusions0.60.71.80.7-0.7-0.7-0.7-0.60.7-1.31.30.1
Short access day 1 locomotion0.50.51.30.6-0.6-0.5-0.6-0.50.6-1.21.2-0.0
Short access day 10 total locomotion0.91.01.60.9-0.9-1.0-1.0-1.01.1-1.31.30.7
Short access total locomotion1.31.33.60.7-0.7-0.7-0.7-0.60.9-1.91.91.2
One hour access (0.3 mA shock)2.22.63.41.8-1.8-1.8-1.8-1.81.5-0.90.9-1.8
Compulsive drug intake0.20.20.5-0.20.20.30.40.3-0.50.7-0.7-0.7
One hour access (shock baseline)2.12.43.11.6-1.6-1.6-1.7-1.61.7-1.61.6-0.5
Social response proportion4.14.46.02.1-2.1-2.1-2.0-2.12.2-2.52.51.0
Social responses5.47.08.83.0-3.0-2.9-2.9-2.92.8-2.22.2-1.5
Social time3.04.04.72.1-2.1-2.2-2.1-2.12.1-2.02.00.2
Soleus weight4.914.417.74.1-4.1-4.1-4.1-4.04.2-3.93.9-0.4
Bone: stiffness1.93.03.71.9-1.9-1.9-1.9-1.81.9-1.61.6-0.3
Tibialis anterior weight0.10.31.0-0.00.00.00.10.1-0.21.0-1.0-1.0
Time to tail flick, vehicle, before self-admin1.51.52.01.4-1.4-1.3-1.4-1.41.3-0.60.6-1.4
Time to tail flick, vehicle, after self-admin0.20.20.6-0.20.20.20.20.2-0.1-0.80.80.5
Time to tail flick, test, before self-admin2.22.15.31.0-1.0-1.0-1.0-1.01.2-2.32.31.6
Time to tail flick, test, after self-admin3.03.14.12.0-2.0-2.0-2.0-2.01.9-1.21.2-1.1
Delta time to tail flick, vehicle, before/after SA0.20.20.3-0.40.40.40.40.4-0.3-0.30.30.6
Delta time to tail flick, test, before/after SA1.41.33.31.2-1.2-1.1-1.2-1.21.10.1-0.1-1.8
Tibia length2.05.67.12.6-2.6-2.6-2.5-2.62.7-2.22.20.0
Ambulatory time before self-admin0.50.51.20.4-0.4-0.5-0.4-0.40.6-1.11.11.1
Ambulatory time after self-admin1.31.42.11.0-1.0-1.1-1.0-1.01.2-1.41.41.4
Bone: tissue strength0.20.20.4-0.40.40.40.50.5-0.50.6-0.6-0.2
Total heroin consumption0.91.02.11.1-1.1-1.1-1.1-1.10.90.0-0.0-1.5
Bone: trabecular number0.61.02.90.7-0.7-0.7-0.7-0.80.41.3-1.3-1.7
Bone: trabecular spacing0.00.10.1-0.30.30.30.20.2-0.2-0.30.3-0.0
Bone: trabecular thickness5.16.17.92.8-2.8-2.8-2.8-2.82.6-1.21.2-2.5
Bone: trabecular tissue density0.71.01.30.9-0.9-1.0-0.9-0.91.0-1.21.20.8
Water consumed over 24 hours0.91.11.90.9-0.9-0.9-0.9-0.91.0-1.41.40.8
Number of responses in last shaping day0.00.00.10.1-0.1-0.0-0.10.00.1-0.40.40.2