Hub : Genes

Tma7

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 LHb gene expression Tma7 0.25 0.12 5.0e-05 0.13 0.12 0.12 0.12 5.1e-04 1.0e-03 7.8e-04 8.7e-04
2 NAcc gene expression Tma7 0.17 0.09 0.0e+00 0.2 0.2 0.19 0.2 3.8e-22 2.1e-22 5.5e-22 4.4e-22
3 Brain gene expression Tma7 0.32 0.13 0.0e+00 0.4 0.41 0.4 0.41 2.3e-39 9.9e-41 4.3e-40 3.3e-40
4 pVTA gene expression Tma7 0.47 0.19 0.0e+00 0.3 0.3 0.29 0.3 1.4e-13 1.2e-13 6.7e-13 1.2e-13
5 Liver gene expression Tma7 0.28 0.11 0.0e+00 0.32 0.32 0.32 0.32 5.9e-37 7.8e-36 9.6e-37 6.0e-37
6 PL gene expression Tma7 0.17 0.09 0.0e+00 0.17 0.16 0.16 0.17 4.3e-18 4.0e-17 7.8e-18 8.0e-19
7 BLA gene expression Tma7 0.22 0.12 3.0e-12 0.2 0.18 0.18 0.19 9.2e-11 5.1e-10 4.6e-10 1.6e-10
8 Adipose gene expression Tma7 0.36 0.12 0.0e+00 0.45 0.45 0.45 0.45 1.4e-55 2.0e-55 1.5e-55 1.2e-55
9 IL gene expression Tma7 0.27 0.15 8.9e-05 0.15 0.19 0.15 0.15 2.2e-04 2.2e-05 2.2e-04 1.6e-04
10 Eye gene expression Tma7 0.38 0.19 1.7e-03 -0 -0.01 -0.02 0.03 3.6e-01 4.6e-01 6.6e-01 1.1e-01

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10
Bone: apparent density0.10.10.60.1-0.1-0.0-0.10.1-0.10.1-0.00.50.8
Area under the delay curve2.02.13.3-1.41.41.51.4-1.21.4-1.41.21.81.6
BMI with tail0.41.22.01.3-1.0-1.0-1.40.9-0.80.8-0.9-1.1-1.4
BMI without tail1.73.45.02.1-1.8-1.8-2.21.8-1.81.8-1.8-1.6-1.6
Body weight5.824.328.55.1-5.0-5.1-5.14.9-4.64.6-4.6-5.3-4.8
Weight adjusted by age0.60.71.50.8-0.6-0.8-0.80.9-0.80.8-0.4-1.2-0.9
Bone surface0.10.10.3-0.20.30.30.3-0.40.4-0.40.50.40.5
Bone volume0.00.10.3-0.00.10.20.1-0.20.2-0.20.30.40.6
Breakpoint value in progressive ratio session0.20.20.60.4-0.4-0.3-0.70.4-0.40.4-0.6-0.1-0.8
Number of licking bursts0.20.20.5-0.50.60.40.5-0.50.4-0.40.5-0.2-0.7
Context. condit. distance diff. score0.00.00.00.1-0.0-0.0-0.10.1-0.10.1-0.1-0.1-0.1
Locomotion velocity, session 10.10.10.3-0.20.20.20.2-0.20.3-0.30.30.40.6
Locomotion distance, session 10.70.81.51.2-1.0-1.0-1.20.9-0.90.9-0.8-0.5-0.3
Locomotion velocity, session 20.20.30.5-0.40.60.50.5-0.60.6-0.60.70.40.2
Locomotion distance, session 20.10.20.70.00.20.2-0.0-0.30.3-0.30.30.70.8
Locomotion velocity, session 30.10.10.60.3-0.2-0.2-0.30.20.1-0.10.00.40.8
Locomotion distance, session 31.61.72.5-1.11.21.21.1-1.21.4-1.41.31.61.6
Stereotopy head waving bouts, day 30.30.31.90.2-0.1-0.3-0.30.1-0.30.3-0.3-1.0-1.4
Stereotopy head waving duration, day 30.40.41.00.5-0.5-0.6-0.50.5-0.60.6-0.6-0.9-1.0
Locomotion velocity, session 70.10.10.80.1-0.2-0.1-0.10.3-0.10.1-0.10.50.9
Locomotion distance, session 71.41.83.4-1.21.21.31.2-1.11.3-1.31.31.61.8
Stereotopy head waving bouts, day 70.00.00.2-0.10.10.10.0-0.20.0-0.0-0.00.30.4
Stereotopy head waving duration, day 70.30.40.60.7-0.7-0.6-0.80.5-0.60.6-0.7-0.4-0.3
Locomotion velocity, session 80.10.20.50.7-0.4-0.3-0.70.3-0.30.3-0.30.10.1
Locomotion distance, session 80.20.30.70.8-0.5-0.4-0.80.4-0.40.3-0.40.40.8
Degree of sensitization distance1.21.21.51.0-1.1-1.1-1.01.2-1.21.2-1.2-1.1-0.8
Degree of sensitization stereotypy0.10.10.40.2-0.3-0.2-0.20.2-0.20.2-0.30.30.6
Conditioned locomotion2.93.44.4-1.81.81.91.8-1.91.7-1.71.62.12.0
Cocaine response after cond. corrected0.70.83.30.6-0.5-0.6-0.60.5-0.70.7-0.7-1.3-1.8
Cocaine response after cond. not corrected2.32.64.81.5-1.4-1.5-1.51.4-1.51.5-1.5-2.0-2.2
Cocaine response before conditioning0.81.01.41.1-1.2-1.1-1.21.2-0.90.9-0.9-0.6-0.1
Saline control response1.21.52.21.2-1.4-1.3-1.21.5-1.41.4-1.5-0.50.1
Bone: connectivity density0.40.62.8-0.60.40.60.6-0.40.5-0.50.51.31.7
Bone: cortical apparent density0.30.30.7-0.60.50.50.5-0.50.5-0.50.40.70.8
Bone: cortical area0.20.30.8-0.50.50.40.6-0.50.5-0.50.6-0.5-0.9
Bone: cortical porosity0.20.21.4-0.20.10.20.3-0.10.1-0.10.10.91.2
Bone: cortical porosity0.40.42.0-0.40.40.50.5-0.30.3-0.30.31.11.4
Bone: cortical thickness0.30.63.30.3-0.2-0.4-0.20.3-0.20.2-0.2-1.4-1.8
Bone: cortical thickness0.00.00.1-0.10.10.1-0.0-0.00.1-0.1-0.0-0.1-0.2
Bone: cortical tissue density0.30.40.8-0.60.50.50.5-0.50.5-0.50.40.80.9
Condit. Reinf. active minus inactive responses0.10.10.3-0.2-0.2-0.30.20.4-0.00.0-0.0-0.6-0.4
Condit. Reinf. active-inactive response ratio0.30.31.00.0-0.4-0.50.10.7-0.20.2-0.3-1.0-0.9
Condit. Reinf. active responses0.00.00.1-0.20.10.10.2-0.10.1-0.10.1-0.2-0.4
Condit. Reinf. inactive responses0.40.40.9-0.40.80.80.4-1.00.5-0.50.50.90.5
Incentive salience index mean0.10.10.1-0.30.30.20.4-0.20.3-0.30.3-0.0-0.0
Condit. Reinf. lever presses1.21.61.9-1.21.41.41.1-1.41.3-1.31.31.20.9
Condit. Reinf. active minus inactive responses1.51.92.31.3-1.5-1.5-1.31.5-1.11.1-1.2-1.5-1.5
Condit. Reinf. active-inactive response ratio1.41.42.51.2-1.2-1.3-1.21.1-1.01.0-1.0-1.4-1.6
Condit. Reinf. active responses1.42.02.41.3-1.6-1.6-1.31.6-1.21.2-1.3-1.5-1.4
Condit. Reinf. inactive responses0.00.00.1-0.20.00.00.20.10.1-0.10.10.10.3
Condit. Reinf. lever presses1.82.43.01.5-1.7-1.7-1.51.7-1.31.3-1.4-1.7-1.7
Condit. Reinf. lever reinforcers received1.62.22.71.4-1.6-1.7-1.41.6-1.31.3-1.4-1.6-1.5
Conditioned reinforcement - actives0.30.30.5-0.70.60.60.5-0.70.6-0.60.30.70.3
Conditioned reinforcement - inactives1.11.21.9-1.41.21.11.3-1.11.3-1.31.10.2-0.4
Conditioned locomotion0.40.51.1-0.70.50.60.6-0.60.6-0.60.41.00.9
Patch foraging indifference point 0 sec1.11.72.51.5-1.5-1.5-1.11.6-1.41.4-1.4-0.8-0.2
Patch foraging indifference point AUC0.10.10.20.3-0.2-0.1-0.40.2-0.30.3-0.40.40.2
Delay disc. indifference point, 0s delay0.00.00.1-0.00.10.20.1-0.20.0-0.0-0.10.30.0
Delay disc. indifference point, 16s delay1.01.01.7-0.90.91.01.1-0.90.9-0.90.91.21.3
Delay disc. indifference point, 2s delay0.30.30.4-0.60.50.50.5-0.30.6-0.60.50.60.5
Delay disc. indifference point, 24s delay1.01.01.6-0.90.90.91.1-0.80.9-0.91.01.11.3
Delay disc. indifference point, 4s delay1.51.52.0-1.21.41.31.2-1.21.2-1.21.11.41.0
Delay disc. indifference point, 8s delay2.32.43.6-1.51.41.51.4-1.31.5-1.51.41.81.9
Indifference point function ln k0.50.61.0-0.60.60.70.8-0.81.0-1.01.00.51.0
Indifference point function log k0.50.61.0-0.60.60.70.8-0.81.0-1.01.00.51.0
Patch foraging total patch changes 0 sec1.22.02.81.5-1.6-1.6-1.21.7-1.51.5-1.5-1.1-0.6
Patch foraging total patch changes 12 sec1.01.31.61.1-1.2-1.2-1.01.2-1.21.2-1.2-1.0-0.7
Patch foraging total patch changes 18 sec1.92.43.61.5-1.7-1.6-1.51.9-1.71.7-1.7-1.0-0.9
Patch foraging total patch changes 24 sec2.43.03.71.6-1.9-1.9-1.71.9-1.61.6-1.7-1.7-1.6
Patch foraging total patch changes 6 sec0.20.30.40.5-0.6-0.5-0.40.6-0.60.6-0.60.20.6
Patch foraging time to switch 0 sec0.10.10.2-0.50.40.30.4-0.30.3-0.30.4-0.2-0.5
Patch foraging water rate 0 sec0.10.20.30.5-0.5-0.5-0.30.5-0.50.5-0.5-0.4-0.3
Patch foraging water rate 12 sec0.10.20.30.4-0.5-0.4-0.40.4-0.30.3-0.4-0.4-0.5
Patch foraging water rate 18 sec0.00.10.30.10.0-0.1-0.3-0.10.1-0.1-0.1-0.4-0.5
Patch foraging water rate 24 sec0.71.01.21.0-0.9-1.0-1.10.9-1.01.0-1.1-1.1-1.1
Patch foraging water rate 6 sec0.20.20.40.5-0.6-0.5-0.60.5-0.50.5-0.6-0.3-0.0
Seeking ratio, delayed vs. immediate footshock2.02.33.8-1.31.71.71.4-1.51.3-1.31.52.01.4
Distance traveled before self-admin0.20.20.8-0.40.20.10.5-0.20.4-0.40.9-0.40.2
Distance traveled after self-admin0.50.61.8-0.80.60.61.0-0.50.8-0.81.30.30.6
Extensor digitorum longus weight0.10.50.8-0.90.80.70.8-0.70.8-0.80.80.3-0.1
Bone: elastic displacement0.10.10.7-0.0-0.2-0.2-0.00.2-0.00.0-0.1-0.7-0.8
Bone: elastic work0.40.61.70.6-0.7-0.7-0.60.6-0.50.5-0.5-1.1-1.3
Bone: endosteal estimation0.00.10.20.2-0.2-0.2-0.20.3-0.30.3-0.20.20.4
Bone: endosteal perimeter1.12.22.6-1.51.51.51.5-1.51.5-1.51.61.51.4
Epididymis fat weight0.20.41.20.6-0.7-0.7-0.60.6-0.40.4-0.4-0.8-1.1
Delta time in closed arm before/after self-admin0.20.20.6-0.50.50.60.3-0.70.5-0.50.10.80.1
Delta time in open arm before/after self-admin0.20.20.50.4-0.4-0.4-0.10.5-0.40.4-0.2-0.30.7
Diff in mean of infusions in LGA sessions0.50.53.40.3-0.0-0.2-0.80.1-0.30.3-0.6-0.9-1.8
Delay discount exponential model param2.32.53.41.6-1.5-1.6-1.61.4-1.61.6-1.4-1.8-1.6
Extinction: sum of active levers before priming0.00.00.10.2-0.1-0.1-0.20.2-0.20.2-0.10.3-0.1
Active lever presses in extinction session 60.20.10.40.2-0.6-0.5-0.30.7-0.20.2-0.10.00.4
Bone: final force1.11.83.41.3-1.2-1.3-1.21.2-1.21.2-1.0-1.8-1.8
Bone: final moment1.42.34.51.5-1.3-1.4-1.41.3-1.41.4-1.2-2.0-2.1
Food consumed during 24 hour testing period1.31.61.91.2-1.3-1.3-1.21.4-1.11.1-1.2-1.4-1.1
Glucose0.20.40.60.8-0.7-0.6-0.70.6-0.70.7-0.6-0.00.0
Heart weight3.14.48.11.9-1.9-2.0-1.81.8-2.02.0-1.9-2.6-2.8
Delay discount hyperbolic model param2.32.43.51.6-1.5-1.6-1.51.3-1.61.6-1.3-1.9-1.6
Intermittent access intake day 1-15 change0.80.81.5-1.00.80.71.1-0.91.1-1.11.2-0.10.0
Intermittent access intake escalation0.80.81.6-1.00.80.71.1-0.81.1-1.11.30.10.3
Intermittent access intake escalation 20.30.30.7-0.40.10.00.7-0.20.5-0.50.8-0.7-0.3
Intermitt. access day 1 inactive lever presses0.00.00.10.0-0.1-0.1-0.20.20.0-0.0-0.1-0.2-0.2
Intermitt. access day 15 inactive lever presses0.50.51.0-0.60.90.70.9-0.70.7-0.71.00.1-0.2
Intermitt. access escalation Index0.00.00.20.2-0.1-0.00.10.2-0.20.2-0.10.30.4
Intermittent access day 1 total infusions0.00.00.00.10.10.1-0.0-0.2-0.10.1-0.10.2-0.0
Intermittent access day 15 total infusions0.40.50.9-0.70.70.60.9-0.70.7-0.70.90.30.4
Intermittent access terminal intake (last 3 days)0.20.20.5-0.40.40.40.6-0.50.4-0.40.70.30.4
Intermittent access total infusions0.40.50.7-0.70.70.60.8-0.80.7-0.70.80.60.6
Intermittent access day 1 locomotion0.10.10.3-0.30.40.30.2-0.30.2-0.20.10.50.1
Intermittent access day 15 total locomotion1.31.42.5-1.11.01.11.1-1.11.1-1.11.21.41.6
Intermittent access total locomotion1.41.62.7-1.21.11.21.2-1.21.2-1.21.31.51.6
Intermittent access standard deviation0.30.31.50.0-0.2-0.40.20.10.1-0.10.5-1.2-1.0
Left kidney weight0.71.93.82.0-1.6-1.5-1.61.3-1.41.4-1.3-0.7-0.5
Right kidney weight0.10.41.01.0-0.8-0.7-0.70.5-0.60.6-0.50.00.5
Cocaine induced anxiety0.00.00.2-0.10.40.20.2-0.10.1-0.10.0-0.2-0.4
Post-drug Anxiety0.00.00.1-0.10.30.2-0.2-0.20.1-0.1-0.2-0.0-0.4
Baseline Anxiety0.80.91.4-1.00.80.90.7-0.91.0-1.01.01.01.2
Tail length6.419.421.34.5-4.5-4.5-4.64.5-4.64.6-4.5-4.2-3.4
Length with tail8.631.434.25.8-5.8-5.8-5.65.7-5.65.6-5.5-5.8-4.6
Length without tail5.812.715.83.6-3.8-3.8-3.33.6-3.43.4-3.3-4.0-3.3
Times rat made contact with spout0.70.81.20.8-0.9-0.9-0.81.0-0.90.9-0.9-1.1-1.0
Lifetime Intake0.40.50.6-0.70.70.70.8-0.80.7-0.70.80.70.7
Liver weight, left0.10.20.40.4-0.3-0.2-0.40.3-0.60.6-0.60.40.6
Liver weight, right1.32.13.01.7-1.5-1.5-1.71.4-1.61.6-1.6-0.8-0.6
Locomotor activity5.58.79.83.1-3.0-3.0-3.03.0-3.13.1-3.0-2.8-2.1
Locomotor testing distance4.47.49.03.0-2.8-2.8-2.82.8-2.82.8-2.8-2.5-1.9
Locomotor testing rearing0.10.10.20.3-0.3-0.3-0.20.4-0.40.4-0.4-0.3-0.3
Locomotion in novel chamber0.10.10.3-0.40.30.30.3-0.30.4-0.40.5-0.10.2
Locomotion in novel chamber post-restriction0.40.50.80.7-0.9-0.8-0.70.8-0.70.7-0.7-0.4-0.0
Fecal boli incidents, locomotor time 10.80.91.41.1-0.7-0.8-1.00.5-1.01.0-0.9-0.9-1.2
Change in fecal boli incidents, locomotor task0.10.10.2-0.40.00.10.20.20.4-0.40.00.30.2
Time >=10cm from walls, locomotor time 10.60.61.2-0.60.40.61.0-0.60.7-0.70.80.91.1
Bouts of movement, locomotor time 10.20.20.60.4-0.2-0.3-0.50.3-0.40.4-0.4-0.3-0.8
Total resting periods, locomotor time 10.10.20.80.3-0.2-0.2-0.40.3-0.30.3-0.4-0.2-0.9
Rest time, locomotor task time 10.40.40.9-0.60.80.80.4-0.90.5-0.50.50.9-0.1
Distance moved, locomotor task time 11.31.42.51.1-1.3-1.3-0.91.4-1.01.0-1.0-1.6-0.8
Vertical activity count, locomotor time 11.01.11.41.2-1.0-1.0-1.11.1-1.11.1-0.9-1.1-0.5
Time >=10cm from walls, locomotor time 21.21.21.51.2-1.2-1.2-0.91.0-1.21.2-1.1-1.1-0.9
Bouts of movement, locomotor time 20.10.10.3-0.50.20.20.2-0.20.4-0.40.3-0.1-0.2
Total resting periods, locomotor time 20.30.30.6-0.80.50.40.4-0.50.7-0.70.50.20.0
Rest time, locomotor task time 20.10.10.20.00.20.2-0.3-0.3-0.10.1-0.30.4-0.3
Distance moved, locomotor task time 20.70.81.80.7-1.1-1.1-0.51.1-0.70.7-0.5-1.3-0.7
Vertical activity count, locomotor time 20.10.10.10.3-0.3-0.30.00.3-0.30.30.1-0.40.3
Light reinforcement 10.81.42.01.4-1.1-1.1-1.21.0-1.41.4-1.1-1.0-1.0
Light reinforcement 20.20.31.1-0.10.40.50.1-0.60.4-0.40.40.91.1
Bone: marrow area0.00.10.20.3-0.3-0.2-0.30.3-0.30.3-0.30.10.4
Bone: maximum diameter0.30.50.7-0.70.80.70.7-0.80.8-0.80.80.0-0.3
Bone: maximum force0.71.31.91.1-1.1-1.1-1.11.1-1.11.1-0.9-1.4-1.3
Bone: maximum moment0.91.52.31.2-1.1-1.2-1.11.1-1.21.2-1.0-1.5-1.5
Mean time between licks in bursts1.31.92.2-1.51.41.41.5-1.31.5-1.51.51.20.9
Mean num. licks in bursts0.70.81.31.0-1.1-1.0-1.01.1-0.90.9-1.0-0.30.2
Cd content in liver2.83.14.31.4-1.6-1.7-1.41.8-1.81.8-1.7-2.1-2.0
Co content in liver0.10.10.2-0.50.20.10.4-0.10.4-0.40.3-0.3-0.2
Cu content in liver4.35.26.52.5-2.3-2.2-2.52.1-2.62.6-2.5-1.8-1.7
Fe content in liver2.22.63.31.3-1.5-1.6-1.31.7-1.81.8-1.7-1.8-1.6
K content in liver1.21.22.21.5-1.0-1.0-1.50.8-1.11.1-1.1-0.7-0.9
Mg content in liver0.10.10.30.5-0.0-0.0-0.5-0.0-0.10.1-0.10.2-0.1
Mn content in liver0.30.40.60.8-0.8-0.7-0.80.8-0.50.5-0.6-0.10.4
Na content in liver0.40.40.70.6-0.7-0.6-0.60.7-0.80.8-0.8-0.3-0.0
Rb content in liver1.11.42.40.6-1.0-1.1-0.61.4-1.21.3-1.2-1.6-1.5
Se content in liver0.20.20.40.6-0.3-0.3-0.60.2-0.50.5-0.4-0.3-0.5
Sr content in liver0.00.00.10.2-0.00.0-0.2-0.20.1-0.10.10.20.1
Zn content in liver4.85.36.32.5-2.3-2.3-2.52.3-2.42.4-2.4-1.9-1.8
Bone: minimum diameter0.40.81.1-0.90.90.90.9-0.91.0-1.01.00.70.5
Time in familiar zone, hab. session 11.11.01.6-1.21.31.21.2-1.10.9-0.90.90.70.4
Time in novel zone, hab. session 10.50.50.80.8-0.9-0.9-0.70.9-0.60.6-0.6-0.8-0.3
Total zone transitions, hab. session 10.30.50.91.0-0.8-0.7-0.90.7-0.60.6-0.5-0.20.3
Total locomotion distance, hab. session 10.20.30.70.8-0.6-0.5-0.70.5-0.60.6-0.6-0.2-0.1
Locomotion velocity, hab. session 10.30.40.80.9-0.6-0.6-0.80.6-0.60.6-0.7-0.10.0
Time in familiar zone, hab. session 20.50.60.8-0.90.90.80.8-0.80.8-0.80.70.3-0.2
Time in novel zone, hab. session 20.10.10.30.1-0.2-0.20.00.3-0.20.2-0.00.10.6
Total zone transitions, hab. session 20.00.00.20.4-0.2-0.2-0.3-0.0-0.00.00.10.00.1
Total locomotion distance, hab. session 20.40.51.01.0-0.6-0.6-0.90.5-0.80.8-0.7-0.3-0.4
Locomotion velocity, hab. session 20.30.40.90.9-0.6-0.5-0.90.4-0.70.7-0.7-0.2-0.2
Novel to familiar place preference ratio0.70.71.20.9-0.9-0.7-0.80.8-1.01.0-0.80.41.1
Novelty place preference0.70.81.50.9-0.9-0.7-0.70.8-0.90.9-0.80.51.2
Time in novel zone, NPP test0.80.91.21.0-1.1-0.9-0.90.9-1.11.1-0.90.20.9
Total zone transitions, NPP test1.72.44.32.1-1.8-1.6-2.01.5-1.51.4-1.5-0.9-0.4
Total locomotion distance, NPP test1.11.52.41.5-1.2-1.2-1.51.1-1.21.2-1.2-0.8-0.8
Locomotion velocity, NPP test1.11.52.61.6-1.3-1.2-1.51.1-1.31.2-1.3-0.8-0.6
Intraocular pressure0.91.32.51.0-1.1-1.1-1.01.1-1.31.3-1.6-0.8-0.6
Delta distance traveled before/after self-admin0.10.10.2-0.20.30.20.3-0.00.2-0.20.30.50.4
Delta ambulatory time before/after self-admin0.30.30.70.6-0.6-0.6-0.60.8-0.60.6-0.6-0.3-0.3
Parametrial fat weight0.91.82.31.5-1.5-1.5-1.31.5-1.41.4-1.4-1.2-0.7
Pavlov. Cond. lever latency4.55.77.02.3-2.6-2.6-2.42.7-2.52.5-2.5-2.2-1.5
Pavlov. Cond. magazine entry latency5.77.48.8-2.83.02.92.8-2.92.9-2.92.92.21.5
Pavlov. Cond. change in total contacts1.51.62.0-1.41.41.41.4-1.31.3-1.31.30.90.5
Pavlov. Cond. index score5.57.08.6-2.72.92.82.7-2.92.8-2.82.82.21.4
Pavlov. Cond. latency score5.57.08.4-2.62.92.82.7-2.92.8-2.82.82.31.5
Pavlov. Cond. lever contacts2.42.83.5-1.61.91.81.6-1.91.8-1.81.81.50.9
Pavlov. Cond. magazine entry number6.58.19.83.0-3.1-3.1-2.93.1-3.03.0-2.9-2.5-1.6
Pavlov. Cond. intertrial magazine entries0.20.30.40.6-0.6-0.6-0.60.6-0.60.6-0.6-0.4-0.3
Pavlov. Cond. lever-magazine prob. diff.4.86.07.6-2.62.82.62.5-2.72.6-2.62.61.91.0
Pavlov. Cond. response bias6.07.28.9-2.83.02.92.7-3.02.9-2.92.82.21.3
Pavlov. Cond. lever latency0.20.30.4-0.40.60.60.4-0.60.3-0.30.40.60.6
Pavlov. Cond. magazine entry latency0.10.20.3-0.30.40.40.3-0.50.6-0.60.50.2-0.1
Pavlov. Cond. change in total contacts1.92.63.31.6-1.6-1.7-1.61.6-1.41.4-1.5-1.8-1.8
Pavlov. Cond. index score0.10.10.50.2-0.2-0.2-0.20.10.1-0.1-0.1-0.4-0.7
Pavlov. Cond. latency score0.00.10.40.1-0.1-0.1-0.10.00.2-0.2-0.0-0.3-0.6
Pavlov. Cond. lever contacts0.60.81.11.0-1.0-1.0-1.01.0-0.70.7-0.9-0.9-0.8
Pavlov. Cond. magazine entry number0.40.50.70.7-0.7-0.7-0.70.8-0.80.9-0.8-0.5-0.1
Pavlov. Cond. intertrial magazine entries0.40.50.8-0.90.70.70.9-0.60.6-0.60.70.60.9
Pavlov. Cond. lever-magazine prob. diff.0.10.10.40.2-0.1-0.2-0.20.00.1-0.10.0-0.4-0.7
Pavlov. Cond. response bias0.00.00.20.1-0.1-0.1-0.10.00.2-0.20.1-0.2-0.5
Time in closed arm before self-admin0.91.01.80.9-1.3-1.3-0.51.2-0.90.9-0.7-1.4-0.7
Time in closed arm after self-admin0.00.00.2-0.1-0.00.10.2-0.20.1-0.1-0.1-0.1-0.5
Time in open arm before self-admin0.50.61.0-0.51.01.00.6-0.90.6-0.50.80.90.5
Time in open arm after self-admin0.60.74.4-0.30.40.50.4-0.30.3-0.30.61.22.1
Bone: periosteal estimation0.00.00.10.00.0-0.0-0.0-0.0-0.00.00.1-0.2-0.3
Bone: periosteal perimeter1.11.72.2-1.41.41.41.4-1.41.4-1.41.51.00.8
Bone: post-yield work0.00.00.10.4-0.2-0.1-0.30.1-0.20.2-0.1-0.00.0
Progressive ratio test 1 active lever presses0.10.10.3-0.20.10.10.3-0.00.2-0.20.10.50.4
Progressive ratio test 1 breakpoint0.10.10.4-0.30.20.20.4-0.10.2-0.20.10.60.4
Progressive ratio test 1 inactive lever presses0.30.40.6-0.80.70.60.7-0.50.7-0.70.50.2-0.5
Progressive ratio test 2 active lever presses0.80.91.1-1.01.00.91.0-0.91.0-1.01.00.90.8
Progressive ratio test 2 breakpoint0.50.60.8-0.80.80.70.9-0.70.8-0.80.80.60.6
Progressive ratio test 2 inactive lever presses1.31.52.3-1.41.41.21.5-1.21.3-1.31.50.5-0.0
Incentive Sensitization - Responses1.21.21.6-1.31.21.11.2-1.11.2-1.21.20.80.5
Incentive Sensitization - Breakpoint1.21.21.5-1.21.21.11.2-1.11.2-1.21.20.70.5
Sum of active levers in priming session hrs 5-60.60.60.90.9-0.8-0.8-1.00.9-0.90.9-0.5-0.6-0.3
Progressive ratio3.54.04.92.2-2.1-2.1-2.02.1-2.22.2-1.9-1.7-1.1
Food seeking constrained by brief footshock1.11.32.0-1.10.91.01.4-1.11.1-1.11.40.81.1
Seeking ratio, punishment vs. effort5.56.88.1-2.82.72.72.8-2.72.8-2.82.62.11.6
Retroperitoneal fat weight0.31.01.71.2-1.3-1.2-1.11.0-1.01.0-1.0-0.9-0.2
Reaction time number correct0.60.91.2-1.10.90.91.1-0.91.0-1.01.10.70.8
Reaction time mean minus median0.10.20.60.5-0.3-0.3-0.70.3-0.30.3-0.5-0.1-0.4
Reaction time mean minus median AUC0.30.40.80.6-0.5-0.5-0.90.6-0.50.5-0.8-0.2-0.6
Reaction time num false alarms0.30.50.7-0.70.70.60.8-0.50.6-0.60.70.70.9
Reaction time num false alarms AUC0.10.20.8-0.40.30.30.6-0.10.3-0.30.40.40.9
Reaction time trials correct on left0.60.91.2-1.10.90.91.1-0.91.0-1.01.10.70.8
Reaction time trials on left0.71.01.3-1.10.90.91.1-0.91.0-1.01.10.70.8
Reaction time mean0.00.00.1-0.1-0.00.1-0.0-0.20.2-0.20.10.20.3
Reaction time mean AUC0.10.10.3-0.20.10.10.1-0.20.3-0.30.20.40.6
Median of all reaction times0.10.10.3-0.40.10.10.3-0.20.4-0.40.40.30.6
Reaction time omissions0.20.30.6-0.80.50.40.8-0.40.5-0.50.60.40.5
Reaction time false alarm rate0.00.00.2-0.00.00.00.10.1-0.10.1-0.00.20.4
Reaction time premature initiation rate1.92.63.61.6-1.8-1.8-1.41.9-1.71.7-1.4-1.6-1.1
Reaction time premature initiations0.71.01.60.9-1.2-1.2-0.71.3-1.01.0-0.6-1.1-0.6
Std. dev. reaction times0.10.10.20.3-0.3-0.3-0.50.2-0.20.2-0.30.10.1
Reaction time trials completed0.71.01.3-1.10.90.91.1-0.91.0-1.01.10.70.8
Reaction time trials AUC0.91.31.7-1.31.01.11.3-1.11.2-1.21.20.90.9
Run reversals in cocaine runway, females2.62.63.3-1.81.51.61.7-1.71.8-1.81.61.21.1
Run reversals in cocaine runway, males1.21.22.01.2-0.9-1.1-0.61.1-1.21.2-0.7-1.4-1.4
Latency to leave start box in cocaine runway0.80.91.51.0-0.8-0.8-0.90.8-1.01.0-1.1-0.8-1.2
Latency to leave start box in cocaine runway, F1.81.93.61.2-1.2-1.3-1.21.2-1.21.2-1.4-1.8-1.9
Latency to leave start box in cocaine runway, M0.10.10.70.10.30.30.1-0.2-0.10.10.20.80.5
Std. dev. time between licks in bursts4.35.16.3-2.42.52.42.4-2.52.4-2.42.51.50.8
Total sessions with >9 infusions0.20.20.5-0.40.40.40.3-0.50.3-0.30.2-0.1-0.7
Short access day 1 total inactive lever presses5.35.97.6-2.82.52.52.4-2.62.8-2.82.22.11.4
Short access day 10 total inactive lever presses0.30.42.50.1-0.0-0.2-0.40.3-0.00.0-0.2-1.0-1.6
Short access day 1 total infusions0.91.01.5-1.21.21.10.9-1.21.1-1.10.70.90.2
Short access day 10 total infusions0.20.20.5-0.40.30.30.5-0.40.4-0.40.50.50.7
Short access total infusions1.01.11.4-1.10.91.01.0-1.11.0-1.01.01.21.1
Short access day 1 locomotion0.00.00.0-0.10.20.20.2-0.10.1-0.10.10.2-0.1
Short access day 10 total locomotion0.10.10.3-0.2-0.1-0.00.20.00.2-0.20.10.40.5
Short access total locomotion0.00.00.3-0.1-0.00.00.00.00.0-0.0-0.10.50.4
One hour access (0.3 mA shock)0.50.61.4-0.60.60.60.8-0.60.6-0.60.70.91.2
Compulsive drug intake0.30.31.1-0.40.30.50.3-0.40.4-0.40.11.01.1
One hour access (shock baseline)0.00.00.2-0.10.20.00.3-0.10.1-0.10.4-0.10.0
Social response proportion0.30.30.60.4-0.8-0.7-0.30.8-0.50.5-0.4-0.8-0.1
Social responses0.40.50.70.7-0.8-0.8-0.80.8-0.80.8-0.8-0.6-0.3
Social time0.30.40.7-0.60.70.50.7-0.80.6-0.60.8-0.20.2
Soleus weight3.610.611.83.4-3.3-3.3-3.43.2-3.23.2-3.2-3.3-3.1
Bone: stiffness0.10.20.30.5-0.5-0.5-0.40.5-0.50.5-0.4-0.5-0.4
Tibialis anterior weight0.00.10.60.0-0.1-0.2-0.10.00.1-0.10.0-0.5-0.8
Time to tail flick, vehicle, before self-admin2.12.22.61.6-1.4-1.4-1.51.4-1.61.6-1.6-1.3-1.2
Time to tail flick, vehicle, after self-admin1.01.12.60.9-1.0-1.1-1.00.9-0.90.9-0.8-1.6-1.1
Time to tail flick, test, before self-admin0.10.10.20.3-0.4-0.3-0.40.3-0.30.3-0.40.30.5
Time to tail flick, test, after self-admin0.00.00.20.00.10.00.0-0.1-0.00.00.2-0.2-0.4
Delta time to tail flick, vehicle, before/after SA0.40.40.6-0.80.60.40.6-0.60.8-0.80.8-0.1-0.1
Delta time to tail flick, test, before/after SA0.30.20.4-0.50.60.50.6-0.50.5-0.50.60.1-0.0
Tibia length6.418.122.44.7-4.4-4.4-4.74.2-4.14.1-4.1-4.1-3.5
Ambulatory time before self-admin0.40.41.2-0.70.50.50.8-0.50.7-0.71.1-0.00.2
Ambulatory time after self-admin0.30.41.3-0.50.30.30.8-0.00.5-0.51.10.30.8
Bone: tissue strength2.92.84.31.6-1.6-1.7-1.41.6-1.61.6-1.5-2.1-2.0
Total heroin consumption1.01.22.11.0-1.1-1.2-0.81.2-1.01.0-1.0-1.4-1.3
Bone: trabecular number1.01.64.2-1.01.01.11.0-1.01.1-1.11.11.82.0
Bone: trabecular spacing1.92.45.41.3-1.3-1.4-1.31.3-1.41.4-1.4-2.1-2.3
Bone: trabecular thickness0.10.10.60.3-0.2-0.1-0.30.1-0.10.1-0.10.50.8
Bone: trabecular tissue density0.30.40.60.7-0.6-0.6-0.80.5-0.70.7-0.7-0.4-0.2
Water consumed over 24 hours0.10.10.80.1-0.0-0.1-0.10.0-0.00.0-0.0-0.7-0.9
Number of responses in last shaping day0.40.50.8-0.70.90.80.8-0.80.7-0.70.60.4-0.1