Hub : Genes

Cep112

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Eye gene expression Cep112 0.25 0.14 9.1e-03 0.05 0.13 0.12 0.09 6.7e-02 4.5e-03 7.9e-03 2.0e-02
2 NAcc gene expression Cep112 0.11 0.05 1.7e-16 0.09 0.12 0.11 0.13 5.9e-13 5.8e-18 1.7e-16 1.7e-18
3 Adipose gene expression Cep112 0.33 0.11 0.0e+00 0.23 0.25 0.24 0.25 1.1e-25 2.9e-27 6.4e-26 3.2e-27
4 Brain alternative TSS XM_039085652.2 0.04 0.03 7.6e-03 0.01 0.01 0.01 0.01 3.9e-02 5.2e-02 5.5e-02 3.0e-02
5 Adipose alternative TSS XM_039085652.2 0.05 0.04 1.3e-04 0.03 0.02 0.02 0.02 5.3e-04 1.3e-03 1.4e-03 1.4e-03
6 Adipose alternative TSS XM_039085652.2 0.06 0.04 1.4e-05 0.03 0.03 0.03 0.03 1.5e-04 3.4e-04 3.4e-04 3.8e-04
7 Brain mRNA stability Cep112 0.06 0.04 2.9e-03 0.01 0.02 0.02 0.01 1.8e-02 4.5e-03 6.8e-03 1.2e-02
8 Brain gene expression Cep112 0.25 0.09 0.0e+00 0.25 0.18 0.25 0.16 2.1e-23 2.5e-16 4.9e-23 6.1e-15
9 IC gene expression Cep112 0.17 0.12 7.9e-04 0.12 0.03 0.07 0.1 7.7e-06 1.9e-02 4.6e-04 3.8e-05
10 PL gene expression Cep112 0.18 0.07 0.0e+00 0.22 0.19 0.21 0.22 1.5e-23 2.1e-20 1.9e-22 2.8e-23
11 Liver gene expression Cep112 0.1 0.05 1.1e-09 0.09 0.08 0.05 0.07 1.1e-09 7.2e-09 3.7e-06 5.8e-08
12 IC alternative TSS NM_001105849.1 0.09 0.05 4.5e-03 0.02 0.07 0.03 0.03 4.7e-02 8.2e-04 1.6e-02 1.9e-02
13 BLA gene expression Cep112 0.13 0.08 8.2e-04 0.01 0.05 0.01 0.03 1.0e-01 1.4e-03 5.2e-02 1.6e-02
14 OFC gene expression Cep112 0.24 0.12 5.7e-04 0.1 0.13 0.19 0.11 2.0e-03 5.0e-04 3.0e-05 1.4e-03
15 LHb gene expression Cep112 0.35 0.12 1.1e-06 0.24 0.2 0.28 0.13 2.3e-06 2.0e-05 3.1e-07 5.8e-04
16 Adipose mRNA stability Cep112 0.09 0.05 1.8e-07 0.06 0.06 0.06 0.06 4.2e-07 8.6e-07 8.8e-07 5.1e-07
17 Adipose intron excision ratio chr10_94231466_94238130 0.05 0.03 8.8e-05 0.05 0.04 0.03 0.04 5.6e-06 3.6e-05 1.7e-04 1.5e-05
18 NAcc intron excision ratio chr10_93881501_93922648 0.03 0.02 1.7e-03 0.02 0.01 0.02 0.02 4.4e-04 2.5e-03 6.4e-04 7.4e-04
19 NAcc mRNA stability Cep112 0.03 0.02 4.3e-04 0.02 0.02 0.01 0.02 6.0e-04 2.9e-04 1.7e-03 3.9e-04
20 Liver mRNA stability Cep112 0.04 0.03 6.4e-04 0.02 0.03 0.02 0.02 2.8e-03 7.5e-04 4.8e-03 3.4e-03
21 IL gene expression Cep112 0.34 0.14 2.5e-04 0.02 0.1 0.03 0.01 1.2e-01 1.9e-03 6.2e-02 2.2e-01

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21
Bone: apparent density0.61.12.80.20.8-0.1-0.3-0.8-0.8-0.81.11.11.1-1.1-1.00.80.21.4-1.4-1.7-0.9-1.4-1.41.2
Area under the delay curve0.00.00.20.2-0.20.10.1-0.4-0.4-0.40.10.10.1-0.1-0.1-0.3-0.1-0.00.10.1-0.0-0.30.0-0.3
BMI with tail5.518.832.9-3.1-4.22.43.4-1.2-1.21.7-5.5-5.5-5.55.55.7-4.0-2.6-5.65.55.23.64.85.1-4.1
BMI without tail6.519.837.8-3.7-4.32.63.5-2.1-2.11.9-5.8-5.8-5.85.86.1-3.7-2.8-5.85.65.13.64.74.8-3.6
Body weight7.834.055.2-6.1-7.25.56.3-3.6-3.6-0.9-7.4-7.4-7.47.47.0-6.5-5.2-6.56.05.91.64.05.0-5.8
Weight adjusted by age1.11.74.20.5-0.9-0.20.51.51.50.6-1.2-1.2-1.21.20.9-1.30.1-1.31.21.91.51.82.0-2.0
Bone surface1.52.86.2-1.3-0.21.40.9-2.5-2.5-2.51.01.01.0-1.0-1.10.1-0.81.6-1.7-2.2-2.5-2.4-2.31.3
Bone volume1.01.95.7-1.3-0.71.61.2-2.2-2.2-2.40.40.40.4-0.4-0.6-0.4-1.01.1-1.1-1.5-2.0-1.9-1.70.6
Breakpoint value in progressive ratio session1.41.76.41.40.8-1.7-1.51.11.12.5-0.2-0.2-0.20.20.40.81.7-0.60.51.62.22.01.5-0.0
Number of licking bursts0.20.30.9-0.7-0.90.90.8-0.1-0.1-1.0-0.4-0.4-0.40.40.1-0.9-0.9-0.20.30.1-0.5-0.30.0-0.9
Context. condit. distance diff. score0.30.30.9-0.4-0.80.40.70.10.1-0.0-0.7-0.7-0.70.70.5-0.7-0.4-0.40.30.80.20.40.6-0.9
Locomotion velocity, session 10.00.00.2-0.1-0.1-0.0-0.2-0.4-0.40.10.00.00.0-0.0-0.00.20.30.2-0.20.4-0.2-0.0-0.10.3
Locomotion distance, session 10.10.10.30.10.1-0.2-0.30.00.00.5-0.2-0.2-0.20.20.20.00.4-0.40.40.60.40.60.4-0.0
Locomotion velocity, session 20.70.92.80.51.3-0.9-1.3-0.1-0.10.91.01.01.0-1.0-0.71.61.10.7-0.6-0.80.1-0.1-0.81.7
Locomotion distance, session 20.40.61.90.81.2-1.1-1.20.20.21.40.40.40.4-0.4-0.21.21.2-0.00.1-0.10.80.6-0.01.1
Locomotion velocity, session 31.01.13.31.30.9-1.4-1.01.71.71.8-0.0-0.0-0.00.00.20.51.0-0.70.80.91.31.51.2-0.1
Locomotion distance, session 30.10.10.70.30.0-0.00.20.80.8-0.30.00.00.0-0.0-0.4-0.30.1-0.10.2-0.2-0.3-0.10.1-0.4
Stereotopy head waving bouts, day 34.14.89.72.93.1-3.0-3.11.51.51.92.62.62.6-2.6-1.92.72.11.9-1.8-0.90.5-0.3-0.92.1
Stereotopy head waving duration, day 32.42.85.42.32.3-2.2-2.31.31.31.22.12.12.1-2.1-1.61.91.71.6-1.5-0.60.3-0.4-0.71.4
Locomotion velocity, session 70.30.30.90.70.5-0.7-0.70.70.70.9-0.1-0.1-0.10.10.10.30.9-0.30.30.40.90.80.6-0.1
Locomotion distance, session 70.30.30.8-0.6-0.80.80.9-0.2-0.2-0.8-0.7-0.7-0.70.70.2-0.8-0.5-0.50.6-0.2-0.2-0.20.1-0.7
Stereotopy head waving bouts, day 71.92.25.02.12.0-2.2-2.21.91.91.91.21.21.2-1.2-1.01.71.80.7-0.7-0.10.80.60.11.0
Stereotopy head waving duration, day 73.44.18.32.82.8-2.8-2.92.42.42.12.02.02.0-2.0-1.72.42.41.4-1.3-0.80.70.3-0.31.5
Locomotion velocity, session 80.00.10.20.1-0.0-0.00.00.00.0-0.30.20.20.2-0.2-0.40.10.40.3-0.30.0-0.3-0.2-0.30.2
Locomotion distance, session 80.10.10.3-0.10.1-0.2-0.1-0.4-0.40.6-0.3-0.3-0.30.30.20.30.4-0.20.10.30.30.30.10.3
Degree of sensitization distance0.20.20.8-0.6-0.40.60.3-0.9-0.9-0.4-0.2-0.2-0.20.20.2-0.1-0.40.1-0.2-0.3-0.1-0.4-0.40.1
Degree of sensitization stereotypy1.01.13.91.31.0-1.5-1.31.71.72.00.10.10.1-0.1-0.00.91.2-0.30.40.71.31.40.90.2
Conditioned locomotion0.20.30.70.50.6-0.5-0.5-0.1-0.10.00.60.60.6-0.6-0.60.70.60.4-0.3-0.50.1-0.4-0.60.8
Cocaine response after cond. corrected0.20.31.1-0.2-0.80.60.60.50.5-1.1-0.1-0.1-0.10.1-0.4-0.7-0.40.2-0.2-0.0-0.9-0.6-0.3-0.7
Cocaine response after cond. not corrected0.30.41.5-0.1-0.80.70.70.90.9-1.2-0.2-0.2-0.20.2-0.7-0.8-0.10.3-0.3-0.2-1.0-0.6-0.2-1.0
Cocaine response before conditioning0.10.10.40.40.2-0.2-0.20.60.6-0.20.20.20.2-0.2-0.70.10.60.4-0.6-0.3-0.3-0.1-0.2-0.0
Saline control response3.14.18.9-1.5-1.60.81.2-0.8-0.81.6-2.4-2.4-2.42.43.0-1.2-1.1-2.82.82.82.32.62.4-1.2
Bone: connectivity density2.33.68.21.02.2-1.1-1.7-1.1-1.10.02.32.32.3-2.3-1.82.41.12.2-2.2-2.3-0.9-1.8-2.32.9
Bone: cortical apparent density1.62.25.92.21.9-2.4-2.21.81.82.41.11.11.1-1.1-0.51.71.30.3-0.10.31.80.70.50.8
Bone: cortical area0.50.72.0-1.2-1.00.91.0-1.4-1.4-0.2-0.9-0.9-0.90.91.0-0.6-0.8-0.70.70.60.40.20.2-0.2
Bone: cortical porosity0.91.02.8-1.6-1.21.61.4-1.7-1.7-1.5-0.5-0.5-0.50.50.2-0.7-0.80.0-0.1-0.4-1.1-0.7-0.70.1
Bone: cortical porosity1.71.84.2-2.0-2.02.02.1-1.7-1.7-1.5-1.3-1.3-1.31.30.9-1.6-1.3-0.80.70.6-0.8-0.10.1-0.9
Bone: cortical thickness2.64.415.61.71.0-2.3-1.62.32.33.9-0.8-0.8-0.80.81.60.71.2-1.92.02.53.93.22.7-0.5
Bone: cortical thickness1.51.77.91.31.4-1.9-1.80.80.82.80.60.60.6-0.60.61.50.8-0.60.91.22.31.50.91.0
Bone: cortical tissue density1.62.25.92.21.9-2.4-2.21.81.82.41.11.11.1-1.1-0.41.61.30.3-0.10.31.80.70.50.8
Condit. Reinf. active minus inactive responses2.12.45.8-2.3-2.02.42.2-2.1-2.1-2.1-1.2-1.2-1.21.20.6-1.7-1.8-0.40.2-0.2-1.7-0.9-0.4-1.1
Condit. Reinf. active-inactive response ratio0.80.82.9-1.0-0.91.31.1-1.3-1.3-1.7-0.1-0.1-0.10.1-0.3-0.8-0.90.4-0.5-0.8-1.5-1.1-0.8-0.4
Condit. Reinf. active responses1.72.15.0-2.2-1.72.22.1-2.2-2.2-1.7-1.2-1.2-1.21.20.7-1.4-1.7-0.50.4-0.4-1.5-0.7-0.4-0.7
Condit. Reinf. inactive responses0.30.30.9-0.9-0.30.70.6-1.0-1.0-0.0-0.6-0.6-0.60.60.7-0.2-0.6-0.50.5-0.1-0.40.10.00.1
Incentive salience index mean1.01.22.8-1.7-1.31.61.5-1.7-1.7-1.2-1.1-1.1-1.11.10.7-1.1-1.1-0.60.5-0.2-0.7-0.3-0.1-0.6
Condit. Reinf. lever presses0.40.51.3-0.3-0.30.10.2-0.1-0.10.7-1.0-1.0-1.01.00.9-0.30.2-1.01.00.41.11.10.9-0.4
Condit. Reinf. active minus inactive responses2.02.66.9-2.2-1.42.32.0-2.6-2.6-2.4-0.3-0.3-0.30.3-0.1-0.8-1.70.4-0.4-1.3-2.5-1.8-1.60.2
Condit. Reinf. active-inactive response ratio1.82.16.2-1.9-1.52.12.0-1.9-1.9-2.5-0.4-0.4-0.40.4-0.2-1.0-1.60.3-0.3-1.3-2.2-1.6-1.3-0.3
Condit. Reinf. active responses2.23.19.8-2.6-1.72.62.1-3.1-3.1-2.3-0.6-0.6-0.60.60.3-0.8-1.90.2-0.4-1.0-2.5-1.7-1.50.3
Condit. Reinf. inactive responses0.40.53.2-0.9-0.10.50.0-1.8-1.80.20.00.00.0-0.00.40.6-0.30.2-0.30.0-0.3-0.4-0.71.1
Condit. Reinf. lever presses1.52.17.3-2.5-1.62.21.8-2.7-2.7-1.2-1.0-1.0-1.01.01.1-0.9-1.8-0.60.4-0.0-1.0-0.5-0.5-0.0
Condit. Reinf. lever reinforcers received2.23.110.0-2.7-1.72.62.1-3.2-3.2-2.3-0.6-0.6-0.60.60.4-0.9-2.00.1-0.3-1.0-2.4-1.6-1.50.2
Conditioned reinforcement - actives0.40.61.7-0.8-0.10.80.5-1.1-1.1-1.30.30.30.3-0.3-0.4-0.1-0.60.7-0.7-1.2-1.0-1.2-1.10.4
Conditioned reinforcement - inactives0.81.23.0-1.5-1.51.71.7-0.8-0.8-1.3-0.7-0.7-0.70.70.9-1.7-1.7-0.80.80.9-0.60.00.4-1.3
Conditioned locomotion1.52.05.1-2.3-2.02.22.1-1.3-1.3-1.8-1.2-1.2-1.21.21.1-1.6-2.0-0.60.40.5-0.9-0.6-0.1-0.9
Patch foraging indifference point 0 sec2.64.812.4-3.5-2.73.02.7-3.3-3.3-1.2-2.1-2.1-2.12.12.5-1.8-2.8-1.51.31.3-0.5-0.00.2-0.7
Patch foraging indifference point AUC0.60.92.2-1.1-1.21.11.0-1.5-1.5-0.5-1.0-1.0-1.01.00.7-0.8-1.1-0.91.00.4-0.60.00.2-0.6
Delay disc. indifference point, 0s delay0.10.10.50.70.0-0.4-0.00.60.6-0.1-0.1-0.1-0.10.1-0.4-0.20.50.2-0.2-0.20.40.10.3-0.4
Delay disc. indifference point, 16s delay0.30.31.3-0.4-0.60.40.4-1.1-1.1-0.1-0.4-0.4-0.40.40.5-0.4-0.6-0.60.70.50.20.10.3-0.4
Delay disc. indifference point, 2s delay0.70.81.50.30.6-0.1-0.4-0.6-0.6-0.61.11.11.1-1.1-0.90.60.01.0-1.0-1.0-1.1-1.2-1.10.9
Delay disc. indifference point, 24s delay1.01.22.3-1.3-1.31.31.2-1.5-1.5-0.7-0.8-0.8-0.80.81.3-1.2-1.5-1.21.40.70.20.20.5-0.8
Delay disc. indifference point, 4s delay0.20.31.00.90.4-0.6-0.50.60.6-0.00.20.20.2-0.2-0.80.21.00.5-0.7-0.4-0.1-0.2-0.10.0
Delay disc. indifference point, 8s delay0.10.20.50.70.0-0.6-0.40.50.50.50.00.00.0-0.00.0-0.00.4-0.20.30.60.70.30.5-0.4
Indifference point function ln k0.91.62.51.31.6-1.4-1.41.01.00.81.31.31.3-1.3-1.11.51.61.4-1.5-1.00.8-0.5-0.81.3
Indifference point function log k0.91.62.51.31.6-1.4-1.41.01.00.81.31.31.3-1.3-1.11.51.61.4-1.5-1.00.8-0.5-0.81.3
Patch foraging total patch changes 0 sec2.34.311.3-3.4-2.52.82.5-3.3-3.3-1.0-2.0-2.0-2.02.02.4-1.5-2.6-1.41.21.2-0.5-0.00.1-0.5
Patch foraging total patch changes 12 sec2.63.411.4-2.9-2.32.62.1-3.4-3.4-1.5-1.4-1.4-1.41.41.5-1.3-2.5-0.90.90.6-1.2-0.7-0.4-0.4
Patch foraging total patch changes 18 sec1.92.84.5-2.1-2.01.81.8-2.0-2.0-0.1-1.9-1.9-1.91.92.1-1.4-1.9-1.91.91.6-0.01.01.1-1.1
Patch foraging total patch changes 24 sec2.03.47.8-2.5-2.52.32.1-2.8-2.8-1.0-2.0-2.0-2.02.01.8-1.7-2.0-1.41.31.2-0.60.20.5-1.1
Patch foraging total patch changes 6 sec4.87.315.2-3.9-3.73.63.6-3.0-3.0-1.7-2.9-2.9-2.92.92.8-2.7-3.4-2.32.21.7-0.80.30.8-1.8
Patch foraging time to switch 0 sec0.10.20.80.1-0.30.10.30.80.8-0.0-0.2-0.2-0.20.20.4-0.7-0.2-0.40.40.50.40.60.7-0.9
Patch foraging water rate 0 sec0.30.72.6-1.4-0.81.00.7-1.6-1.6-0.5-0.6-0.6-0.60.60.6-0.0-1.10.0-0.2-0.2-0.8-0.7-0.70.5
Patch foraging water rate 12 sec0.20.41.7-0.3-0.60.10.30.20.20.4-0.7-0.7-0.70.70.8-0.5-0.3-0.70.61.30.50.80.8-0.6
Patch foraging water rate 18 sec0.20.31.60.40.7-0.7-1.00.20.21.30.10.10.1-0.10.30.90.70.0-0.00.40.90.50.10.8
Patch foraging water rate 24 sec0.50.81.51.11.2-1.0-1.21.01.00.60.80.80.8-0.8-0.80.91.10.9-1.0-0.60.3-0.1-0.30.7
Patch foraging water rate 6 sec0.40.61.71.01.3-1.3-1.10.30.31.30.50.50.5-0.5-0.31.30.90.3-0.3-0.40.70.2-0.21.1
Seeking ratio, delayed vs. immediate footshock0.50.61.8-0.5-0.60.70.90.40.4-0.4-0.7-0.7-0.70.70.8-1.2-1.2-0.70.60.20.20.50.9-1.3
Distance traveled before self-admin1.21.53.31.71.7-1.6-1.81.61.61.11.41.41.4-1.4-1.11.40.90.7-0.8-0.3-0.20.1-0.20.9
Distance traveled after self-admin0.20.30.70.40.4-0.5-0.70.40.40.50.30.30.3-0.3-0.50.90.70.4-0.5-0.0-0.7-0.2-0.40.8
Extensor digitorum longus weight1.97.417.20.0-1.70.01.12.22.21.4-3.2-3.2-3.23.22.7-2.70.0-3.43.33.23.13.74.1-3.4
Bone: elastic displacement0.91.03.11.31.3-1.5-1.51.41.41.70.50.50.5-0.5-0.31.11.20.1-0.10.41.00.90.50.4
Bone: elastic work0.40.51.5-0.1-0.1-0.3-0.20.30.31.2-0.7-0.7-0.70.71.10.00.1-0.90.81.11.21.21.0-0.1
Bone: endosteal estimation6.915.144.6-5.5-4.45.95.1-6.1-6.1-6.7-1.2-1.2-1.21.20.2-3.1-3.90.9-1.2-1.9-5.1-4.0-3.1-0.4
Bone: endosteal perimeter6.513.742.5-5.1-4.35.74.9-5.5-5.5-6.5-1.4-1.4-1.41.40.2-3.3-3.80.8-1.1-1.7-4.9-3.8-2.7-0.9
Epididymis fat weight4.415.224.3-3.2-4.32.93.8-1.0-1.00.4-4.9-4.9-4.94.94.8-4.2-3.1-4.74.54.51.63.74.3-4.4
Delta time in closed arm before/after self-admin0.50.51.30.60.6-0.3-0.50.70.7-0.50.60.60.6-0.6-1.10.40.60.9-0.9-1.1-0.7-0.9-0.70.3
Delta time in open arm before/after self-admin0.60.61.61.01.3-1.0-1.00.50.50.61.01.01.0-1.0-0.60.80.50.6-0.6-0.60.0-0.1-0.20.7
Diff in mean of infusions in LGA sessions1.41.75.20.90.0-1.2-0.81.11.12.0-1.0-1.0-1.01.01.00.11.0-1.21.22.02.32.11.8-0.6
Delay discount exponential model param0.10.10.50.10.4-0.4-0.40.60.60.7-0.1-0.1-0.10.10.10.50.40.0-0.1-0.10.30.50.10.4
Extinction: sum of active levers before priming0.60.71.80.2-0.4-0.3-0.10.30.30.9-0.8-0.8-0.80.80.7-0.50.2-1.00.91.31.21.31.3-1.0
Active lever presses in extinction session 60.40.41.8-0.3-0.0-0.1-0.5-1.3-1.30.9-0.4-0.4-0.40.40.60.60.5-0.1-0.10.80.50.40.00.8
Bone: final force0.30.62.5-1.0-0.40.80.8-1.6-1.6-0.9-0.1-0.1-0.10.10.1-0.0-0.60.3-0.4-0.6-0.8-0.9-0.90.6
Bone: final moment0.40.62.8-0.9-0.30.80.7-1.7-1.7-0.90.10.10.1-0.1-0.00.1-0.50.5-0.6-0.9-0.9-1.1-1.10.8
Food consumed during 24 hour testing period1.41.95.5-1.0-0.40.1-0.1-1.4-1.42.1-1.2-1.2-1.21.22.30.2-0.6-1.71.72.01.71.91.40.3
Glucose0.60.93.10.9-0.2-0.6-0.11.81.80.4-0.5-0.5-0.50.50.1-0.90.7-0.60.60.81.01.31.5-1.5
Heart weight1.21.84.0-0.8-1.71.01.30.10.1-0.3-1.7-1.7-1.71.71.2-1.8-0.7-1.41.31.70.41.11.5-2.0
Delay discount hyperbolic model param0.10.10.5-0.00.3-0.3-0.30.40.40.7-0.3-0.3-0.30.30.20.40.3-0.10.10.00.30.50.20.4
Intermittent access intake day 1-15 change1.63.38.9-2.0-3.02.42.8-0.7-0.7-2.2-2.0-2.0-2.02.01.0-2.7-1.9-1.21.01.0-0.60.10.8-2.4
Intermittent access intake escalation1.73.58.8-2.1-3.02.42.8-0.8-0.8-2.0-2.1-2.1-2.12.11.2-2.7-1.9-1.41.21.1-0.40.20.8-2.3
Intermittent access intake escalation 22.52.86.6-2.2-2.62.52.6-1.0-1.0-2.2-1.8-1.8-1.81.80.8-2.2-1.8-0.90.80.3-1.1-0.40.2-1.8
Intermitt. access day 1 inactive lever presses0.93.57.1-2.0-2.71.92.2-1.0-1.0-0.6-2.2-2.2-2.22.21.9-2.2-1.6-2.01.92.30.11.21.5-2.0
Intermitt. access day 15 inactive lever presses1.32.65.1-1.7-2.31.62.0-1.0-1.0-0.6-2.1-2.1-2.12.11.7-1.9-1.3-1.51.31.80.10.91.2-1.8
Intermitt. access escalation Index0.30.41.21.00.8-1.0-0.90.50.50.50.60.60.6-0.6-0.80.91.10.6-0.6-0.20.2-0.1-0.30.7
Intermittent access day 1 total infusions0.20.31.5-0.8-0.30.70.6-0.8-0.8-0.30.10.10.1-0.10.4-0.4-1.2-0.30.40.4-0.2-0.0-0.0-0.1
Intermittent access day 15 total infusions2.53.88.4-2.6-2.82.72.9-1.9-1.9-1.9-1.8-1.8-1.81.81.6-2.5-2.6-1.41.21.1-0.60.00.6-1.9
Intermittent access terminal intake (last 3 days)3.14.19.5-3.0-2.63.13.0-2.7-2.7-2.6-1.4-1.4-1.41.41.2-2.4-3.0-0.90.80.3-1.6-0.8-0.2-1.5
Intermittent access total infusions1.92.26.6-2.3-1.72.32.2-2.2-2.2-1.9-0.7-0.7-0.70.70.9-1.6-2.6-0.60.50.1-1.2-0.8-0.3-0.9
Intermittent access day 1 locomotion3.13.99.1-2.7-2.52.52.7-1.7-1.7-1.1-1.7-1.7-1.71.72.3-2.4-3.0-2.12.01.80.10.81.1-1.8
Intermittent access day 15 total locomotion2.54.611.0-3.3-2.73.12.9-2.8-2.8-1.7-1.7-1.7-1.71.72.2-2.3-3.2-1.71.71.2-0.70.10.5-1.4
Intermittent access total locomotion6.47.617.1-4.1-3.53.83.7-3.3-3.3-2.0-2.4-2.4-2.42.43.0-3.1-4.0-2.32.21.9-0.70.40.9-2.1
Intermittent access standard deviation2.65.313.0-2.6-3.33.23.6-0.7-0.7-3.0-2.2-2.2-2.22.21.4-3.6-2.9-1.71.70.8-1.4-0.11.0-3.1
Left kidney weight0.41.93.7-0.9-1.50.70.9-0.7-0.70.5-1.9-1.9-1.91.91.6-1.3-0.2-1.41.11.91.21.51.6-1.4
Right kidney weight0.62.96.6-1.1-1.90.81.0-0.9-0.90.6-2.2-2.2-2.22.22.1-1.6-0.5-2.01.82.61.41.92.0-1.7
Cocaine induced anxiety0.40.61.40.60.6-0.3-0.40.20.2-0.61.01.01.0-1.0-1.10.40.61.1-1.2-1.1-0.3-0.7-0.70.4
Post-drug Anxiety1.21.32.21.51.5-1.2-1.31.21.20.41.51.51.5-1.5-1.10.91.21.1-1.1-1.0-0.0-0.2-0.40.6
Baseline Anxiety1.01.22.91.41.5-1.6-1.71.11.11.61.21.21.2-1.2-0.31.40.90.4-0.10.30.50.40.11.0
Tail length1.35.111.5-3.4-2.82.82.7-3.4-3.4-1.0-2.5-2.5-2.52.52.5-1.9-2.6-1.71.41.3-0.50.40.5-1.0
Length with tail2.310.120.3-4.2-4.54.34.3-3.2-3.2-2.8-3.5-3.5-3.53.52.7-3.9-3.7-2.21.71.9-1.90.11.0-3.0
Length without tail1.54.810.6-2.3-3.32.72.9-1.1-1.1-1.8-2.5-2.5-2.52.51.8-3.1-2.4-1.71.51.8-1.00.41.3-2.9
Times rat made contact with spout0.50.61.2-1.1-1.00.90.8-0.9-0.9-0.0-0.7-0.7-0.70.71.0-0.6-1.1-0.80.70.9-0.10.50.5-0.5
Lifetime Intake1.31.65.7-2.0-1.41.91.8-1.9-1.9-1.3-0.6-0.6-0.60.61.0-1.3-2.4-0.60.60.3-0.6-0.4-0.2-0.7
Liver weight, left0.91.53.7-1.9-1.61.91.6-1.9-1.9-1.4-1.1-1.1-1.11.10.7-1.1-1.2-0.40.1-0.1-1.1-0.4-0.3-0.5
Liver weight, right0.71.23.2-0.0-0.5-0.3-0.10.40.41.4-1.1-1.1-1.11.11.2-0.40.2-1.31.31.61.71.81.6-0.8
Locomotor activity1.62.65.2-1.8-1.61.21.4-2.0-2.00.6-1.9-1.9-1.91.92.3-1.0-0.9-1.91.91.70.91.51.2-0.5
Locomotor testing distance1.11.94.4-1.3-1.00.81.0-1.3-1.31.0-1.6-1.6-1.61.62.1-0.8-0.6-1.92.01.51.21.81.4-0.5
Locomotor testing rearing1.32.65.1-1.3-1.10.71.0-1.1-1.11.3-1.9-1.9-1.91.92.2-0.9-0.5-2.22.22.01.92.31.8-0.8
Locomotion in novel chamber0.30.42.61.00.2-1.0-0.80.40.40.7-0.3-0.3-0.30.3-0.50.61.60.2-0.20.50.30.30.20.2
Locomotion in novel chamber post-restriction0.20.31.2-0.40.00.50.20.10.1-0.70.20.20.2-0.2-0.40.2-0.40.4-0.3-0.7-1.1-1.0-0.90.5
Fecal boli incidents, locomotor time 10.30.53.1-0.2-0.70.80.7-0.4-0.4-1.8-0.0-0.0-0.00.0-0.6-1.2-0.30.4-0.5-0.5-0.5-0.8-0.2-1.0
Change in fecal boli incidents, locomotor task1.31.32.40.21.1-0.3-0.7-0.8-0.8-0.11.61.61.6-1.6-0.91.3-0.01.3-1.2-1.0-1.3-1.3-1.51.5
Time >=10cm from walls, locomotor time 10.50.52.40.90.8-0.6-0.41.61.60.00.60.60.6-0.6-0.90.20.50.5-0.5-0.8-0.3-0.1-0.1-0.2
Bouts of movement, locomotor time 11.01.12.2-0.6-1.00.50.70.30.30.4-1.1-1.1-1.11.11.4-1.2-0.7-1.21.11.51.31.21.4-1.4
Total resting periods, locomotor time 10.70.81.8-0.4-0.90.50.70.30.3-0.0-0.9-0.9-0.90.91.0-1.2-0.6-0.90.81.21.00.91.2-1.3
Rest time, locomotor task time 10.20.31.10.70.1-0.3-0.11.11.1-0.60.40.40.4-0.4-0.6-0.50.40.3-0.2-0.20.2-0.00.2-0.7
Distance moved, locomotor task time 10.40.61.9-0.20.2-0.30.00.10.11.4-0.8-0.8-0.80.81.10.3-0.2-1.11.20.41.01.10.80.3
Vertical activity count, locomotor time 10.10.30.9-0.30.10.00.10.30.30.9-0.7-0.7-0.70.70.80.1-0.4-0.70.7-0.10.40.70.5-0.0
Time >=10cm from walls, locomotor time 21.21.86.50.7-0.1-1.1-0.41.11.12.1-1.3-1.3-1.31.30.90.21.8-1.10.91.32.52.11.6-0.3
Bouts of movement, locomotor time 22.23.58.1-0.4-1.0-0.00.60.30.31.9-1.7-1.7-1.71.72.5-1.2-0.7-2.52.52.92.82.82.8-1.8
Total resting periods, locomotor time 21.62.86.8-0.3-0.90.10.70.60.61.5-1.5-1.5-1.51.52.1-1.4-0.7-2.22.22.52.42.52.6-1.9
Rest time, locomotor task time 22.93.77.02.62.1-1.8-1.82.42.4-0.52.42.42.4-2.4-2.60.81.32.3-2.2-1.9-0.6-1.1-0.80.0
Distance moved, locomotor task time 22.32.76.1-0.4-0.5-0.50.1-0.3-0.32.5-2.1-2.1-2.12.12.10.30.8-2.12.11.92.42.51.70.1
Vertical activity count, locomotor time 22.63.68.6-1.8-1.80.91.2-1.3-1.31.4-2.9-2.9-2.92.92.5-0.5-0.1-2.32.21.81.51.81.3-0.2
Light reinforcement 10.61.45.90.40.6-1.0-0.80.40.42.4-0.6-0.6-0.60.61.40.70.1-1.41.71.22.41.71.30.3
Light reinforcement 20.20.21.10.50.3-0.5-0.31.01.00.5-0.2-0.2-0.20.20.2-0.20.0-0.40.60.10.60.40.6-0.5
Bone: marrow area6.614.543.0-5.4-4.25.85.0-5.9-5.9-6.6-1.1-1.1-1.11.10.1-3.0-3.90.9-1.3-1.9-5.1-4.0-3.1-0.4
Bone: maximum diameter2.13.813.2-2.2-1.52.62.1-2.9-2.9-3.60.10.10.1-0.1-0.6-1.0-1.61.2-1.3-1.8-2.9-2.7-2.20.4
Bone: maximum force0.81.43.9-1.8-1.41.81.7-2.0-2.0-1.7-0.7-0.7-0.70.70.6-1.0-1.3-0.1-0.1-0.4-0.9-0.9-0.6-0.1
Bone: maximum moment0.81.44.4-1.8-1.21.71.6-2.1-2.1-1.7-0.5-0.5-0.50.50.5-0.9-1.30.1-0.2-0.6-1.0-1.1-0.80.0
Mean time between licks in bursts1.33.36.2-1.6-2.21.82.1-0.5-0.5-0.8-2.2-2.2-2.22.21.9-2.5-1.7-1.91.71.80.11.11.7-2.4
Mean num. licks in bursts0.10.10.80.10.3-0.4-0.3-0.3-0.30.9-0.1-0.1-0.10.10.50.40.2-0.30.30.50.50.50.30.5
Cd content in liver0.60.62.10.90.7-0.4-0.41.41.4-0.50.80.80.8-0.8-1.10.10.30.8-0.9-0.9-0.9-0.5-0.3-0.3
Co content in liver0.40.51.80.60.3-0.30.11.41.40.4-0.2-0.2-0.20.20.2-0.7-0.3-0.70.90.20.40.81.1-1.3
Cu content in liver0.20.20.6-0.30.10.40.2-0.3-0.3-0.60.40.40.4-0.4-0.3-0.0-0.40.4-0.3-0.8-0.8-0.7-0.60.1
Fe content in liver0.40.41.3-0.20.50.3-0.1-0.2-0.2-0.51.11.11.1-1.1-0.50.2-0.60.6-0.5-0.7-0.9-0.5-0.60.3
K content in liver1.91.83.40.71.3-0.5-1.0-0.0-0.0-0.51.71.71.7-1.7-1.61.20.21.8-1.8-1.9-1.1-1.7-1.71.2
Mg content in liver3.23.35.51.62.3-1.6-2.00.50.50.52.32.32.3-2.3-1.92.21.12.0-1.9-2.1-0.6-1.5-1.82.1
Mn content in liver4.04.59.41.62.4-1.8-2.3-0.5-0.50.52.52.52.5-2.5-2.22.91.72.5-2.5-2.1-1.0-1.8-2.43.1
Na content in liver1.41.53.21.01.6-0.8-1.00.40.4-0.31.81.81.8-1.8-1.40.90.31.5-1.4-1.6-0.6-1.1-1.10.8
Rb content in liver1.61.93.21.31.6-1.1-1.40.50.5-0.21.71.71.7-1.7-1.81.41.01.7-1.7-1.7-0.9-1.2-1.41.2
Se content in liver1.11.32.91.51.3-1.3-1.41.21.20.51.71.71.7-1.7-1.20.90.41.0-0.9-0.4-0.1-0.4-0.30.3
Sr content in liver1.11.01.9-0.7-1.20.60.8-0.3-0.30.1-1.3-1.3-1.31.31.1-1.0-0.5-1.21.11.40.70.91.1-1.0
Zn content in liver0.70.81.90.60.9-0.2-0.40.80.8-0.51.41.41.4-1.4-1.10.1-0.41.0-0.9-1.1-0.6-0.7-0.5-0.3
Bone: minimum diameter5.610.125.0-4.8-4.14.94.5-5.0-5.0-4.8-1.8-1.8-1.81.81.2-2.9-3.6-0.1-0.1-0.3-3.2-2.5-1.6-0.9
Time in familiar zone, hab. session 11.31.33.7-1.5-1.71.71.7-1.6-1.6-1.9-0.8-0.8-0.80.80.2-1.2-0.9-0.10.0-0.1-0.8-1.0-0.5-0.6
Time in novel zone, hab. session 10.80.82.51.01.2-1.3-1.31.01.01.60.60.60.6-0.6-0.01.00.8-0.00.10.30.90.80.40.7
Total zone transitions, hab. session 11.11.63.1-0.6-0.70.20.4-0.7-0.71.1-1.6-1.6-1.61.61.7-0.6-0.1-1.81.81.61.51.71.5-0.5
Total locomotion distance, hab. session 10.71.12.4-0.5-0.0-0.2-0.2-1.3-1.31.6-0.9-0.9-0.90.91.50.30.1-1.31.41.21.31.40.90.6
Locomotion velocity, hab. session 10.60.92.3-0.40.1-0.2-0.3-1.2-1.21.5-0.8-0.8-0.80.81.40.30.0-1.21.31.11.21.40.80.5
Time in familiar zone, hab. session 20.80.82.1-1.3-1.41.41.4-1.0-1.0-1.2-0.9-0.9-0.90.90.4-1.0-0.8-0.30.30.1-0.8-0.4-0.2-0.6
Time in novel zone, hab. session 22.02.04.61.62.1-1.8-2.00.60.61.21.71.71.7-1.7-1.11.91.11.2-1.1-0.90.3-0.4-0.81.7
Total zone transitions, hab. session 21.62.15.3-0.1-0.5-0.4-0.10.10.11.9-1.6-1.6-1.61.61.7-0.30.5-2.02.02.22.12.31.9-0.5
Total locomotion distance, hab. session 21.31.75.6-0.10.1-0.6-0.5-0.9-0.92.4-1.0-1.0-1.01.01.80.50.3-1.71.81.81.82.01.40.5
Locomotion velocity, hab. session 21.11.46.10.20.4-0.9-0.8-0.6-0.62.5-0.8-0.8-0.80.81.50.80.5-1.51.61.61.81.91.30.6
Novel to familiar place preference ratio1.61.74.3-1.9-1.82.02.1-1.4-1.4-1.9-1.0-1.0-1.01.00.7-1.7-1.9-0.40.2-0.2-1.1-0.7-0.2-1.0
Novelty place preference1.11.23.1-1.5-1.51.71.8-1.0-1.0-1.6-0.9-0.9-0.90.90.7-1.5-1.5-0.40.3-0.1-0.8-0.40.0-0.9
Time in novel zone, NPP test0.91.02.5-1.4-1.31.51.6-0.9-0.9-1.4-0.8-0.8-0.80.80.6-1.2-1.4-0.30.2-0.1-0.8-0.4-0.1-0.8
Total zone transitions, NPP test0.60.94.20.50.6-1.1-1.00.10.12.1-0.4-0.4-0.40.40.80.91.0-0.90.91.11.71.50.90.7
Total locomotion distance, NPP test0.81.15.70.21.1-1.1-1.4-1.0-1.02.40.10.10.1-0.10.81.70.8-0.40.40.61.21.00.11.8
Locomotion velocity, NPP test0.71.05.40.20.7-1.0-1.1-0.5-0.52.3-0.4-0.4-0.40.41.11.10.5-0.90.91.11.51.40.71.1
Intraocular pressure0.40.51.3-0.5-0.80.30.4-0.3-0.30.3-1.2-1.2-1.21.20.8-0.50.2-0.70.60.90.30.80.8-0.5
Delta distance traveled before/after self-admin0.30.31.1-0.7-0.50.30.3-1.0-1.00.4-0.7-0.7-0.70.70.60.20.2-0.40.40.40.20.30.10.4
Delta ambulatory time before/after self-admin0.50.63.5-1.0-0.70.80.5-1.9-1.9-0.4-0.4-0.4-0.40.40.30.2-0.10.00.00.1-0.8-0.5-0.70.7
Parametrial fat weight0.92.15.50.61.1-0.4-1.1-0.9-0.9-0.81.41.41.4-1.4-1.71.30.92.1-2.3-1.7-1.7-2.0-2.01.6
Pavlov. Cond. lever latency2.43.05.61.41.8-1.1-1.40.50.5-0.62.42.42.4-2.4-2.11.50.82.3-2.3-1.8-1.2-1.9-1.91.5
Pavlov. Cond. magazine entry latency1.01.33.1-1.8-1.51.61.3-1.7-1.7-0.6-1.2-1.2-1.21.21.1-0.9-1.4-0.80.80.5-0.6-0.00.1-0.5
Pavlov. Cond. change in total contacts2.02.23.5-1.8-1.81.51.6-1.3-1.3-0.1-1.9-1.9-1.91.91.7-1.3-1.3-1.71.71.20.21.01.0-1.1
Pavlov. Cond. index score1.52.03.2-1.8-1.81.51.5-1.4-1.4-0.3-1.8-1.8-1.81.81.6-1.3-1.3-1.51.51.00.10.70.8-1.0
Pavlov. Cond. latency score2.02.54.3-1.7-1.91.51.6-1.0-1.0-0.1-2.1-2.1-2.12.11.8-1.6-1.3-1.91.81.40.31.11.2-1.4
Pavlov. Cond. lever contacts2.52.95.6-1.3-1.71.01.4-0.4-0.40.5-2.4-2.4-2.42.42.1-1.5-0.7-2.32.21.71.21.91.9-1.5
Pavlov. Cond. magazine entry number0.81.02.31.51.3-1.4-1.21.41.40.71.01.01.0-1.0-0.80.81.20.6-0.5-0.50.80.1-0.00.5
Pavlov. Cond. intertrial magazine entries1.72.04.7-2.0-1.82.12.2-1.5-1.5-1.8-1.3-1.3-1.31.31.0-1.8-1.7-0.70.60.3-1.2-0.50.1-1.2
Pavlov. Cond. lever-magazine prob. diff.1.31.62.6-1.6-1.51.41.3-1.3-1.3-0.2-1.6-1.6-1.61.61.4-1.1-1.1-1.41.30.90.10.60.7-0.8
Pavlov. Cond. response bias0.70.92.7-1.4-1.11.21.0-1.7-1.7-0.4-1.0-1.0-1.01.00.9-0.6-0.9-0.70.60.4-0.50.00.0-0.2
Pavlov. Cond. lever latency0.50.71.70.90.2-0.9-0.41.31.31.1-0.5-0.5-0.50.50.4-0.00.8-0.80.80.71.31.21.2-0.5
Pavlov. Cond. magazine entry latency0.30.32.20.60.1-0.1-0.11.51.5-0.30.30.30.3-0.3-0.5-0.5-0.00.2-0.1-0.1-0.30.00.4-1.0
Pavlov. Cond. change in total contacts0.20.41.6-0.5-0.10.60.3-0.6-0.6-0.90.40.40.4-0.4-0.50.0-0.40.7-0.7-0.7-1.3-0.9-0.90.2
Pavlov. Cond. index score0.30.41.5-0.7-0.50.90.6-0.4-0.4-1.20.20.20.2-0.2-0.4-0.5-0.60.4-0.5-0.5-1.2-0.8-0.6-0.3
Pavlov. Cond. latency score0.30.41.8-0.5-0.30.80.5-0.2-0.2-1.20.30.30.3-0.3-0.6-0.5-0.50.6-0.7-0.6-1.3-0.9-0.6-0.4
Pavlov. Cond. lever contacts0.30.41.4-0.7-0.10.60.2-1.2-1.2-0.60.40.40.4-0.5-0.20.2-0.60.6-0.6-0.4-0.9-0.8-0.90.6
Pavlov. Cond. magazine entry number0.40.53.6-0.9-0.30.40.2-1.9-1.9-0.1-0.1-0.1-0.10.10.50.4-0.30.1-0.1-0.1-0.0-0.5-0.71.1
Pavlov. Cond. intertrial magazine entries1.21.811.4-1.9-0.81.20.7-3.4-3.4-0.3-0.5-0.5-0.50.51.10.5-1.0-0.20.20.1-0.5-0.7-1.11.6
Pavlov. Cond. lever-magazine prob. diff.0.30.41.6-0.5-0.40.80.5-0.3-0.3-1.20.30.30.3-0.3-0.5-0.5-0.50.5-0.6-0.5-1.3-0.8-0.6-0.3
Pavlov. Cond. response bias0.20.31.0-0.5-0.10.60.2-0.7-0.7-0.80.40.40.4-0.4-0.40.0-0.50.6-0.6-0.5-1.0-0.8-0.80.2
Time in closed arm before self-admin0.91.22.3-0.7-0.6-0.00.1-1.5-1.51.5-1.1-1.1-1.11.11.40.40.1-1.21.41.41.51.30.70.6
Time in closed arm after self-admin0.70.71.4-0.3-0.60.00.3-0.2-0.20.9-1.2-1.2-1.21.20.9-0.10.5-1.11.20.91.21.10.9-0.2
Time in open arm before self-admin2.02.28.3-0.6-1.61.11.61.11.1-0.8-1.7-1.7-1.71.70.9-2.4-0.8-1.31.21.10.41.11.8-2.9
Time in open arm after self-admin0.30.41.80.1-0.20.30.51.01.0-0.80.00.00.0-0.0-0.2-1.1-0.60.0-0.2-0.1-0.7-0.00.5-1.3
Bone: periosteal estimation4.39.024.8-4.4-3.44.64.0-5.0-5.0-4.8-1.1-1.1-1.11.10.6-2.4-3.20.4-0.7-1.2-3.4-2.8-2.2-0.3
Bone: periosteal perimeter2.84.814.8-3.0-3.03.53.4-2.6-2.6-3.8-1.4-1.4-1.41.40.5-2.6-2.3-0.1-0.0-0.6-2.3-1.7-0.8-1.4
Bone: post-yield work1.72.66.1-2.2-2.32.52.4-1.6-1.6-2.3-1.4-1.4-1.41.41.0-2.2-1.9-0.80.80.1-0.7-0.40.1-1.4
Progressive ratio test 1 active lever presses2.32.86.8-2.4-1.71.91.8-2.6-2.6-0.2-1.4-1.4-1.41.42.2-1.4-2.3-1.71.61.7-0.00.80.8-0.7
Progressive ratio test 1 breakpoint2.32.87.6-2.5-1.71.91.8-2.8-2.8-0.2-1.4-1.4-1.41.42.2-1.3-2.3-1.61.61.6-0.00.70.7-0.6
Progressive ratio test 1 inactive lever presses3.24.58.5-2.9-2.72.42.6-2.4-2.4-0.7-2.4-2.4-2.42.42.4-2.0-2.2-2.01.82.3-0.10.81.0-1.4
Progressive ratio test 2 active lever presses0.60.72.3-1.5-0.91.31.1-1.2-1.2-0.8-0.4-0.4-0.40.40.7-0.7-1.5-0.40.40.3-0.9-0.3-0.2-0.3
Progressive ratio test 2 breakpoint0.70.82.3-1.5-0.91.41.2-1.3-1.3-0.8-0.4-0.4-0.40.40.7-0.7-1.5-0.40.30.3-1.0-0.4-0.3-0.2
Progressive ratio test 2 inactive lever presses0.81.32.9-1.6-1.41.51.5-1.5-1.5-0.7-0.9-0.9-0.90.91.4-1.3-1.7-0.90.91.0-0.10.20.5-0.8
Incentive Sensitization - Responses0.30.41.10.20.50.1-0.00.50.5-0.70.80.80.8-0.8-0.80.1-0.30.6-0.6-1.0-0.8-0.7-0.60.1
Incentive Sensitization - Breakpoint0.40.51.10.20.50.1-0.10.50.5-0.70.90.90.9-0.9-0.90.1-0.30.7-0.7-1.1-1.0-0.8-0.70.1
Sum of active levers in priming session hrs 5-60.50.41.50.70.2-0.9-0.80.00.01.2-0.2-0.2-0.20.20.20.41.0-0.30.21.21.01.00.80.0
Progressive ratio0.20.31.20.4-0.50.20.40.50.5-1.10.00.00.0-0.0-0.7-0.7-0.30.1-0.10.0-1.0-0.6-0.0-0.9
Food seeking constrained by brief footshock0.60.83.1-1.1-0.70.90.7-1.8-1.8-0.8-0.8-0.8-0.80.8-0.10.20.20.1-0.1-0.5-1.3-0.8-1.00.9
Seeking ratio, punishment vs. effort0.30.42.1-1.00.20.40.0-1.4-1.40.6-0.3-0.3-0.30.30.70.6-0.2-0.30.3-0.20.20.3-0.31.0
Retroperitoneal fat weight2.711.720.3-2.8-3.72.33.1-1.1-1.10.8-4.5-4.5-4.54.54.3-3.3-2.3-4.24.04.01.93.33.7-3.4
Reaction time number correct0.71.42.01.41.4-1.2-1.31.01.00.11.31.31.3-1.3-1.41.21.41.3-1.3-1.1-0.5-0.8-0.91.1
Reaction time mean minus median0.00.10.40.0-0.00.10.1-0.1-0.1-0.50.30.30.3-0.3-0.0-0.4-0.60.1-0.2-0.00.1-0.10.1-0.3
Reaction time mean minus median AUC0.41.12.20.50.9-0.3-0.7-0.5-0.5-0.91.51.51.5-1.5-1.20.6-0.11.3-1.3-1.3-0.8-1.3-1.20.9
Reaction time num false alarms1.31.83.7-1.9-1.81.81.9-1.0-1.0-1.0-1.5-1.5-1.51.51.4-1.6-1.5-1.41.40.70.30.40.6-1.1
Reaction time num false alarms AUC1.11.64.4-2.1-1.82.01.9-1.3-1.3-1.3-1.2-1.2-1.21.21.3-1.5-1.6-1.11.10.50.10.00.2-0.7
Reaction time trials correct on left0.71.42.01.41.4-1.2-1.31.01.00.11.31.31.3-1.3-1.41.21.41.3-1.3-1.1-0.5-0.8-0.91.1
Reaction time trials on left0.71.32.01.31.3-1.1-1.30.90.90.01.31.31.3-1.3-1.41.21.31.4-1.3-1.1-0.6-0.9-1.01.1
Reaction time mean0.91.43.00.61.0-0.4-0.9-0.2-0.2-0.71.71.71.7-1.7-1.50.8-0.01.6-1.7-1.2-0.9-1.4-1.30.7
Reaction time mean AUC0.81.22.60.71.0-0.6-0.9-0.1-0.1-0.41.61.61.6-1.6-1.40.90.21.5-1.6-1.0-0.7-1.2-1.20.8
Median of all reaction times1.31.83.70.81.2-0.6-1.2-0.2-0.2-0.51.91.91.9-1.9-1.71.20.31.9-1.9-1.4-1.0-1.5-1.61.1
Reaction time omissions0.30.41.6-0.9-0.40.70.5-1.2-1.2-0.60.20.20.2-0.20.3-0.2-1.30.1-0.10.3-0.7-0.6-0.50.2
Reaction time false alarm rate2.02.75.6-2.4-2.22.22.3-1.2-1.2-1.1-1.7-1.7-1.71.71.8-2.0-2.0-1.71.71.10.30.60.8-1.3
Reaction time premature initiation rate1.62.34.9-1.7-2.21.62.0-0.8-0.8-0.6-1.7-1.7-1.71.71.6-1.9-1.5-1.41.31.50.70.81.1-1.7
Reaction time premature initiations0.20.31.2-0.7-1.10.70.9-0.3-0.3-0.5-0.6-0.6-0.60.60.5-0.8-0.5-0.30.20.50.30.00.2-0.7
Std. dev. reaction times0.40.71.60.10.40.1-0.2-0.4-0.4-0.91.11.11.1-1.1-0.90.2-0.41.1-1.3-0.8-0.9-1.1-1.00.4
Reaction time trials completed0.71.32.01.31.3-1.1-1.30.90.90.01.31.31.3-1.3-1.41.21.31.4-1.3-1.1-0.6-0.9-1.01.1
Reaction time trials AUC0.71.42.01.31.4-1.1-1.30.90.90.11.31.31.3-1.3-1.41.21.41.4-1.3-1.1-0.5-0.9-1.01.1
Run reversals in cocaine runway, females3.93.910.9-0.2-0.80.10.71.11.11.7-1.2-1.2-1.21.22.7-1.7-1.2-2.52.72.63.23.23.3-2.3
Run reversals in cocaine runway, males0.50.50.90.80.5-0.6-0.61.01.0-0.30.80.80.8-0.8-0.90.40.60.8-0.8-0.4-0.2-0.5-0.50.3
Latency to leave start box in cocaine runway1.31.55.71.31.9-1.7-1.60.90.92.40.80.80.8-0.80.21.40.9-0.50.80.31.71.50.80.9
Latency to leave start box in cocaine runway, F1.51.75.61.11.1-1.4-1.01.51.52.4-0.4-0.4-0.40.40.80.40.8-1.41.61.12.02.31.8-0.4
Latency to leave start box in cocaine runway, M1.21.23.10.71.6-1.2-1.4-0.4-0.41.21.51.51.5-1.5-0.41.70.70.6-0.3-0.50.4-0.1-0.71.8
Std. dev. time between licks in bursts0.50.72.40.40.4-0.7-0.40.40.41.6-0.6-0.6-0.60.61.00.20.2-1.11.10.91.21.41.2-0.1
Total sessions with >9 infusions0.50.61.4-0.6-0.80.50.9-0.2-0.20.1-0.7-0.7-0.70.70.9-0.9-1.2-0.90.91.00.80.60.8-0.8
Short access day 1 total inactive lever presses0.10.10.4-0.6-0.50.50.4-0.4-0.4-0.4-0.3-0.3-0.30.30.3-0.3-0.60.1-0.30.2-0.3-0.3-0.2-0.1
Short access day 10 total inactive lever presses0.30.71.5-0.5-1.20.60.90.10.1-0.8-1.2-1.2-1.21.20.6-1.2-0.1-0.60.50.80.20.30.7-1.1
Short access day 1 total infusions0.20.21.10.10.0-0.20.01.01.00.5-0.2-0.2-0.20.20.3-0.1-0.4-0.40.40.60.60.50.5-0.3
Short access day 10 total infusions2.53.17.3-2.6-2.02.12.1-2.7-2.7-0.7-1.5-1.5-1.51.52.1-1.6-2.6-1.61.51.50.10.40.6-0.8
Short access total infusions0.30.42.0-1.1-0.60.80.8-1.1-1.1-0.4-0.1-0.1-0.10.10.6-0.4-1.4-0.30.30.50.1-0.2-0.1-0.1
Short access day 1 locomotion2.22.86.2-1.4-1.70.91.3-0.2-0.20.8-2.1-2.1-2.12.12.5-1.3-1.5-2.12.02.31.61.61.7-1.0
Short access day 10 total locomotion2.95.310.4-3.2-3.03.03.0-2.6-2.6-1.4-2.3-2.3-2.32.32.5-2.6-3.0-2.22.01.9-0.80.51.0-1.7
Short access total locomotion3.94.77.8-2.4-2.62.02.4-1.3-1.3-0.3-2.4-2.4-2.42.42.8-2.4-2.6-2.52.32.60.81.41.8-2.0
One hour access (0.3 mA shock)1.21.44.3-1.8-1.62.01.8-0.8-0.8-2.1-0.4-0.4-0.40.40.2-1.5-2.0-0.10.0-0.0-1.4-1.0-0.5-1.0
Compulsive drug intake1.01.24.2-0.20.10.60.2-0.2-0.2-1.70.70.70.7-0.7-1.40.1-0.01.3-1.4-1.9-2.1-1.9-1.60.4
One hour access (shock baseline)0.50.81.9-1.2-1.11.11.2-1.0-1.0-0.6-0.7-0.7-0.70.71.0-1.2-1.4-0.80.80.60.30.30.5-0.9
Social response proportion0.10.20.8-0.8-0.30.70.30.30.3-0.40.00.00.0-0.00.2-0.1-0.90.1-0.1-0.2-0.5-0.5-0.4-0.0
Social responses1.41.94.6-2.1-1.61.71.5-1.4-1.4-0.1-1.5-1.5-1.51.51.8-1.0-1.7-1.41.31.20.30.60.5-0.5
Social time0.20.20.8-0.3-0.60.60.70.40.4-0.9-0.1-0.1-0.10.1-0.3-0.7-0.5-0.00.0-0.0-0.7-0.3-0.1-0.8
Soleus weight0.72.25.2-0.9-1.61.21.60.50.5-0.9-1.9-1.9-1.91.91.2-2.3-0.7-1.71.60.80.41.11.6-2.2
Bone: stiffness0.40.71.6-1.3-0.81.31.1-1.3-1.3-1.2-0.3-0.3-0.30.30.3-0.6-1.00.1-0.2-0.6-0.7-0.8-0.60.0
Tibialis anterior weight1.65.39.6-1.5-2.01.11.7-0.1-0.10.9-3.0-3.0-3.03.03.1-2.2-1.1-3.12.92.71.92.82.9-2.2
Time to tail flick, vehicle, before self-admin0.60.72.4-0.2-0.40.70.6-1.1-1.1-1.50.50.50.5-0.5-0.9-0.7-0.70.7-0.8-0.4-1.4-1.0-0.6-0.6
Time to tail flick, vehicle, after self-admin0.30.41.30.20.40.10.0-0.0-0.0-1.00.60.60.6-0.6-0.80.20.30.6-0.4-1.2-1.1-1.1-0.90.6
Time to tail flick, test, before self-admin0.60.72.6-0.7-0.10.90.8-1.3-1.3-1.30.40.40.4-0.4-0.3-0.4-0.70.6-0.7-1.1-1.6-0.9-0.70.0
Time to tail flick, test, after self-admin0.80.82.3-1.2-0.81.31.2-1.5-1.5-1.3-0.2-0.2-0.20.20.1-0.6-1.40.1-0.2-0.5-1.5-0.9-0.7-0.1
Delta time to tail flick, vehicle, before/after SA0.80.83.0-0.00.8-0.2-0.5-0.2-0.2-0.40.80.80.8-0.8-0.61.10.30.9-0.8-1.4-0.9-1.3-1.51.7
Delta time to tail flick, test, before/after SA0.30.31.6-0.2-0.50.50.50.40.4-1.30.20.20.2-0.2-0.7-0.4-0.60.4-0.3-0.4-0.8-1.0-0.7-0.3
Tibia length0.72.04.4-1.4-1.91.62.0-0.2-0.2-1.0-1.6-1.6-1.61.61.2-2.1-1.6-1.41.20.9-0.40.61.1-2.0
Ambulatory time before self-admin1.32.04.41.82.1-1.9-2.02.02.01.41.51.51.5-1.5-1.01.60.90.7-0.8-0.60.10.2-0.21.0
Ambulatory time after self-admin0.50.62.20.71.1-1.0-1.30.40.41.30.50.50.5-0.5-0.41.51.00.4-0.4-0.2-0.10.1-0.41.4
Bone: tissue strength1.11.12.31.51.5-1.5-1.41.31.31.00.90.90.9-0.9-0.91.21.40.7-0.7-0.70.40.1-0.20.8
Total heroin consumption0.10.10.20.10.2-0.3-0.4-0.3-0.30.30.30.30.3-0.3-0.30.4-0.00.2-0.20.20.20.0-0.20.3
Bone: trabecular number1.72.75.00.81.8-0.8-1.2-0.9-0.9-0.42.02.02.0-2.0-1.71.80.82.1-2.1-2.2-1.2-1.8-2.12.2
Bone: trabecular spacing0.91.24.1-0.5-1.40.40.70.40.40.5-1.3-1.3-1.31.31.1-0.9-0.3-1.41.42.00.91.31.3-1.2
Bone: trabecular thickness0.50.61.8-0.6-0.20.80.6-1.2-1.2-1.40.30.30.3-0.3-0.4-0.2-0.70.6-0.7-1.2-1.1-1.3-1.00.3
Bone: trabecular tissue density0.10.20.90.50.1-0.5-0.10.90.90.5-0.2-0.2-0.20.20.10.00.2-0.10.10.30.40.20.4-0.3
Water consumed over 24 hours0.81.04.70.10.4-0.7-0.8-0.3-0.32.2-0.5-0.5-0.50.51.30.70.0-1.21.31.51.61.61.10.5
Number of responses in last shaping day1.11.22.5-0.3-1.40.41.00.20.2-0.1-1.2-1.2-1.21.21.0-1.5-0.5-1.11.01.51.31.11.4-1.6