Hub : Genes

Cep112

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose alternative polyA XM_039085653.1 0.07 0.04 4.1e-09 0.05 0.07 0.06 0.06 3.1e-06 2.3e-08 1.1e-07 1.1e-07
2 Adipose isoform ratio XM_039085653.1 0.06 0.04 1.9e-07 0.03 0.05 0.04 0.05 9.7e-05 2.3e-06 1.3e-05 5.6e-06
3 Adipose isoform ratio XR_005489759.1 0.04 0.03 7.7e-05 0.02 0.02 0.02 0.02 1.9e-03 1.2e-03 1.7e-03 2.4e-03
4 Eye gene expression Cep112 0.3 0.14 3.0e-03 0.14 0.18 0.09 0.12 4.1e-03 9.2e-04 1.6e-02 7.6e-03
5 Adipose isoform ratio XM_039085648.1 0.02 0.01 9.6e-03 0.01 0 -0 0 2.5e-02 1.1e-01 4.0e-01 2.3e-01
6 Adipose alternative polyA XM_039085647.1 0.03 0.02 3.5e-04 0.01 0.02 0.01 0.01 9.5e-03 1.6e-03 8.4e-03 1.0e-02
7 Adipose gene expression Cep112 0.39 0.13 0.0e+00 0.23 0.24 0.23 0.24 1.0e-25 1.5e-26 8.3e-26 4.4e-26
8 Liver gene expression Cep112 0.08 0.04 9.1e-08 0.04 0.06 0.06 0.05 2.2e-05 3.0e-07 9.7e-07 1.8e-06
9 Brain mRNA stability Cep112 0.04 0.03 4.8e-03 0.04 0.02 0.03 0.03 2.8e-04 3.2e-03 1.0e-03 7.3e-04
10 NAcc gene expression Cep112 0.11 0.05 2.5e-11 0.07 0.1 0.08 0.09 3.4e-08 1.5e-11 6.3e-10 3.0e-10
11 NAcc intron excision ratio chr10_93381939_93423087 0.03 0.02 8.6e-03 0.01 0.02 0.01 0.01 7.6e-03 5.2e-03 2.8e-02 9.6e-03
12 Brain gene expression Cep112 0.21 0.08 0.0e+00 0.13 0.12 0.21 0.11 2.0e-12 1.3e-11 7.1e-19 1.1e-10
13 NAcc mRNA stability Cep112 0.02 0.02 5.9e-03 0.01 0.02 0.01 0.01 1.1e-02 5.5e-03 1.5e-02 2.4e-02
14 BLA gene expression Cep112 0.19 0.14 5.0e-04 0.04 0.06 0.06 0.06 5.1e-03 2.7e-04 2.9e-04 4.1e-04
15 Adipose mRNA stability Cep112 0.1 0.08 1.2e-06 0.06 0.05 0.05 0.06 1.0e-06 5.9e-06 6.1e-06 5.1e-07
16 LHb gene expression Cep112 0.41 0.14 5.7e-07 0.31 0.13 0.18 0.12 3.2e-08 6.6e-04 4.7e-05 9.6e-04
17 Liver mRNA stability Cep112 0.03 0.02 2.6e-03 0.01 0.02 0 0.01 2.2e-02 3.1e-03 1.2e-01 1.6e-02
18 Adipose intron excision ratio chr10_93731914_93738578 0.05 0.03 1.1e-04 0.04 0.04 0.02 0.04 3.5e-05 4.8e-05 1.0e-03 4.6e-05
19 Brain isoform ratio XR_005489759.1 0.03 0.02 6.2e-03 0.02 0.01 -0 0.01 4.1e-03 5.4e-02 3.7e-01 5.1e-02
20 PL gene expression Cep112 0.18 0.07 0.0e+00 0.18 0.19 0.2 0.2 1.2e-19 1.0e-20 1.3e-21 3.7e-21

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20
Bone: apparent density0.40.72.2-0.4-0.3-0.30.1-0.40.80.0-0.41.50.5-0.8-0.8-1.10.6-1.1-1.2-1.21.11.1-0.9
Area under the delay curve0.10.10.50.10.10.10.10.6-0.10.3-0.10.5-0.3-0.30.2-0.1-0.4-0.7-0.20.1-0.10.0-0.0
BMI with tail4.715.231.6-0.9-1.0-1.1-2.4-0.1-1.71.24.0-4.2-3.64.94.44.4-3.55.25.64.6-5.6-5.65.3
BMI without tail3.57.217.9-1.8-1.8-1.8-2.4-1.60.11.33.2-2.5-2.63.52.82.1-2.04.23.62.0-3.5-3.53.5
Body weight4.719.938.7-3.4-3.4-3.5-4.7-2.40.73.65.7-3.5-5.53.55.62.7-4.95.26.23.1-5.6-5.75.7
Weight adjusted by age1.61.84.91.21.21.10.42.2-1.9-0.40.2-2.1-0.60.90.82.0-1.00.01.62.2-1.2-1.41.1
Bone surface1.83.28.9-2.0-2.0-1.9-1.3-1.82.71.50.53.0-0.2-2.3-0.3-2.7-0.1-1.5-1.5-2.71.51.4-1.3
Bone volume1.52.57.2-2.0-1.9-1.9-1.5-1.62.31.70.82.7-0.8-1.90.2-2.2-0.7-1.2-0.9-2.00.90.8-0.5
Breakpoint value in progressive ratio session1.31.53.71.11.11.10.71.9-1.7-1.1-0.1-1.80.31.70.11.90.30.71.31.8-0.9-1.20.4
Number of licking bursts0.30.41.1-0.6-0.7-0.7-0.8-0.40.51.00.60.8-0.8-0.80.8-0.4-1.0-0.0-0.0-0.1-0.1-0.20.3
Context. condit. distance diff. score0.20.20.6-0.1-0.1-0.1-0.3-0.3-0.20.40.5-0.1-0.70.20.70.4-0.70.40.80.6-0.4-0.60.7
Locomotion velocity, session 10.00.00.2-0.1-0.1-0.1-0.10.10.1-0.00.1-0.4-0.00.1-0.00.00.0-0.20.1-0.00.1-0.2-0.1
Locomotion distance, session 10.10.10.80.20.20.30.10.4-0.4-0.30.1-0.9-0.00.40.10.5-0.1-0.10.30.5-0.2-0.40.1
Locomotion velocity, session 20.50.62.10.30.40.40.60.2-0.1-1.0-0.7-0.21.20.2-1.2-0.11.5-0.3-0.7-0.50.80.6-1.3
Locomotion distance, session 20.40.51.40.70.70.80.80.7-0.7-1.2-0.6-1.01.00.9-0.80.71.1-0.0-0.20.40.10.0-0.7
Locomotion velocity, session 31.41.63.81.71.71.71.31.5-2.0-1.5-0.7-1.60.81.5-0.51.80.6-0.30.51.6-0.7-0.70.4
Locomotion distance, session 30.10.21.40.30.30.30.30.5-0.2-0.1-0.30.50.1-0.6-0.1-0.1-0.1-1.2-0.50.00.20.3-0.1
Stereotopy head waving bouts, day 33.84.58.52.62.62.72.91.9-1.9-2.9-2.8-0.72.80.7-2.70.72.8-1.4-1.60.21.71.4-2.0
Stereotopy head waving duration, day 32.12.54.72.02.02.02.21.6-1.4-2.0-2.1-0.32.00.3-2.00.41.8-1.4-1.30.21.31.1-1.4
Locomotion velocity, session 70.40.41.20.90.90.90.71.1-1.0-0.8-0.4-0.30.40.7-0.20.90.3-0.20.10.9-0.4-0.40.1
Locomotion distance, session 70.30.41.0-0.7-0.7-0.7-0.7-0.40.60.90.61.0-0.7-0.60.7-0.5-0.8-0.0-0.0-0.3-0.2-0.10.4
Stereotopy head waving bouts, day 72.12.44.82.12.12.12.01.8-1.9-2.2-1.7-1.41.81.1-1.51.31.7-0.7-0.21.00.30.3-0.8
Stereotopy head waving duration, day 73.64.48.22.82.82.82.92.4-2.2-2.9-2.6-1.32.70.6-2.41.02.4-1.5-0.90.71.21.2-1.7
Locomotion velocity, session 80.10.10.7-0.0-0.00.00.0-0.00.2-0.0-0.10.50.2-0.5-0.2-0.30.1-0.8-0.3-0.30.60.2-0.4
Locomotion distance, session 80.00.00.20.10.10.10.0-0.3-0.2-0.30.1-0.30.10.5-0.10.30.20.20.20.20.0-0.2-0.0
Degree of sensitization distance0.30.30.8-0.8-0.8-0.8-0.6-0.90.80.60.50.6-0.4-0.20.3-0.6-0.20.80.0-0.50.10.10.1
Degree of sensitization stereotypy1.31.53.11.61.61.61.31.6-1.8-1.6-0.9-1.61.11.2-0.71.50.9-0.10.51.3-0.4-0.3-0.2
Conditioned locomotion0.10.20.40.10.20.20.3-0.10.1-0.3-0.40.60.5-0.1-0.6-0.20.6-0.1-0.4-0.40.50.5-0.6
Cocaine response after cond. corrected0.30.31.8-0.3-0.3-0.3-0.3-0.20.40.70.11.4-0.5-1.00.4-0.6-0.7-0.3-0.4-0.30.30.30.1
Cocaine response after cond. not corrected0.30.42.4-0.1-0.2-0.2-0.30.10.30.80.01.5-0.4-1.40.4-0.6-0.7-0.7-0.4-0.30.40.4-0.1
Cocaine response before conditioning0.20.21.30.40.40.40.40.5-0.2-0.2-0.50.50.4-0.7-0.4-0.10.2-1.2-0.5-0.10.40.4-0.6
Saline control response2.33.16.9-0.7-0.6-0.7-1.2-0.6-0.50.41.9-2.1-1.52.61.81.9-1.12.42.41.8-2.6-2.52.2
Bone: connectivity density1.52.35.00.20.30.31.0-0.40.7-1.1-1.51.41.9-0.7-2.2-1.42.2-1.4-2.1-1.92.12.0-2.2
Bone: cortical apparent density1.82.34.52.12.12.02.01.2-2.1-2.1-1.5-1.71.32.0-1.11.71.30.80.01.40.00.00.2
Bone: cortical area1.01.52.7-1.7-1.6-1.6-1.7-1.61.21.21.60.1-1.30.71.1-0.1-1.11.40.7-0.1-1.0-1.11.0
Bone: cortical porosity1.51.73.8-1.9-1.9-1.9-1.8-1.61.91.61.41.2-1.0-1.10.9-1.3-0.9-0.1-0.0-1.2-0.1-0.0-0.0
Bone: cortical porosity1.92.04.4-2.0-2.0-2.0-2.1-1.51.61.91.90.9-1.7-0.81.6-0.8-1.70.20.5-0.5-0.8-0.70.7
Bone: cortical thickness3.35.417.91.92.01.91.21.5-3.0-2.1-0.1-3.60.34.20.23.70.42.62.03.3-2.2-2.31.9
Bone: cortical thickness1.51.75.91.31.41.31.30.8-1.6-1.9-0.8-1.81.12.4-0.91.71.31.30.21.2-0.5-0.70.0
Bone: cortical tissue density1.72.24.32.02.02.01.91.2-2.1-2.1-1.4-1.71.32.0-1.11.61.30.80.11.4-0.00.00.2
Condit. Reinf. active minus inactive responses2.73.06.4-2.4-2.4-2.4-2.3-2.52.22.41.81.2-1.9-1.31.6-1.5-1.70.50.4-1.1-0.4-0.30.8
Condit. Reinf. active-inactive response ratio0.91.02.2-1.2-1.2-1.2-1.0-1.41.41.30.61.2-0.7-1.50.5-1.4-0.7-0.4-0.3-1.20.50.5-0.2
Condit. Reinf. active responses2.22.76.8-2.3-2.3-2.3-2.2-2.62.12.21.81.1-1.7-1.01.4-1.4-1.40.70.2-1.1-0.4-0.30.8
Condit. Reinf. inactive responses0.30.41.3-0.9-0.9-0.9-0.8-1.10.70.60.70.1-0.60.30.4-0.2-0.20.50.1-0.3-0.4-0.40.5
Incentive salience index mean1.21.53.5-1.7-1.7-1.7-1.7-1.91.51.61.40.5-1.3-0.61.2-0.8-1.10.70.5-0.6-0.5-0.40.6
Condit. Reinf. lever presses0.40.61.3-0.1-0.1-0.1-0.4-0.0-0.50.10.7-1.0-0.50.90.81.0-0.61.01.11.0-1.1-1.10.9
Condit. Reinf. active minus inactive responses3.13.88.8-2.7-2.7-2.6-2.2-2.93.02.31.42.3-1.3-2.00.8-2.5-1.0-0.3-1.0-2.30.60.6-0.4
Condit. Reinf. active-inactive response ratio2.93.06.4-2.3-2.3-2.3-1.9-2.12.52.21.22.2-1.2-2.10.9-2.2-1.2-0.2-1.0-1.90.60.6-0.3
Condit. Reinf. active responses3.24.411.4-3.0-3.0-2.9-2.5-3.43.22.41.72.4-1.4-1.80.9-2.5-1.00.1-0.8-2.40.40.4-0.2
Condit. Reinf. inactive responses0.40.52.9-1.0-1.0-1.0-0.7-1.71.10.30.50.6-0.00.3-0.2-0.70.50.3-0.1-0.90.10.0-0.1
Condit. Reinf. lever presses2.33.18.4-2.6-2.6-2.6-2.5-2.92.32.02.10.8-1.7-0.21.4-1.1-1.21.30.3-1.1-0.7-0.80.9
Condit. Reinf. lever reinforcers received3.14.411.5-3.0-3.0-3.0-2.5-3.43.22.51.82.2-1.5-1.61.1-2.4-1.10.3-0.7-2.30.30.3-0.0
Conditioned reinforcement - actives1.61.64.20.30.30.30.9-0.50.5-0.9-1.30.91.6-0.6-1.8-1.21.8-0.8-1.9-1.51.81.8-2.1
Conditioned reinforcement - inactives0.70.82.1-1.2-1.2-1.2-1.2-1.51.01.21.10.2-1.1-0.30.9-0.5-1.0-0.00.3-0.4-0.5-0.50.6
Conditioned locomotion1.41.74.0-1.9-1.9-1.8-1.5-2.02.01.61.01.4-1.0-1.00.5-1.6-0.80.4-0.1-1.50.20.3-0.2
Patch foraging indifference point 0 sec4.06.514.9-3.6-3.6-3.6-3.4-3.92.92.93.20.0-2.90.42.3-1.1-2.02.71.7-1.0-1.4-1.61.8
Patch foraging indifference point AUC0.50.52.2-0.9-0.9-0.9-0.9-1.50.80.90.70.6-0.7-0.30.6-0.5-0.60.60.2-0.4-0.3-0.10.6
Delay disc. indifference point, 0s delay0.20.21.10.60.60.60.41.0-0.6-0.2-0.40.10.1-0.4-0.10.2-0.3-0.7-0.10.40.10.10.0
Delay disc. indifference point, 16s delay0.10.10.3-0.2-0.2-0.2-0.3-0.1-0.00.40.4-0.1-0.50.40.50.2-0.40.30.40.3-0.6-0.40.4
Delay disc. indifference point, 2s delay0.50.61.4-0.1-0.1-0.10.3-0.20.60.0-0.61.10.4-0.9-0.9-1.10.6-1.2-1.2-1.11.01.1-0.9
Delay disc. indifference point, 24s delay1.01.01.9-1.1-1.2-1.1-1.2-0.60.71.21.30.3-1.40.31.3-0.0-1.30.60.70.1-1.1-1.01.0
Delay disc. indifference point, 4s delay0.40.51.20.80.80.80.81.0-0.5-0.5-0.80.60.6-0.6-0.5-0.00.3-1.1-0.60.00.60.6-0.7
Delay disc. indifference point, 8s delay0.40.41.10.90.90.90.71.1-1.0-0.5-0.5-0.50.10.5-0.10.70.0-0.60.00.8-0.3-0.20.1
Indifference point function ln k0.81.12.21.01.01.01.31.0-0.5-1.3-1.4-0.01.4-0.0-1.5-0.11.3-0.9-1.1-0.31.31.0-1.4
Indifference point function log k0.81.12.21.01.01.01.31.0-0.5-1.3-1.4-0.01.4-0.0-1.5-0.11.3-0.9-1.1-0.31.31.0-1.4
Patch foraging total patch changes 0 sec3.76.014.8-3.5-3.5-3.5-3.3-3.92.82.83.0-0.1-2.70.52.1-1.1-1.82.61.6-1.0-1.3-1.51.7
Patch foraging total patch changes 12 sec3.74.813.5-3.1-3.1-3.1-2.9-3.72.82.72.50.8-2.3-0.51.8-1.6-1.71.70.6-1.4-0.8-0.71.4
Patch foraging total patch changes 18 sec2.32.95.4-1.9-1.9-1.9-2.1-2.31.11.82.2-0.6-2.10.72.00.1-1.71.91.60.3-1.8-1.71.9
Patch foraging total patch changes 24 sec3.23.97.5-2.6-2.6-2.6-2.7-2.72.02.52.50.2-2.50.02.1-0.7-2.11.61.3-0.4-1.3-1.51.8
Patch foraging total patch changes 6 sec5.48.014.7-3.7-3.7-3.8-3.8-3.82.93.53.60.5-3.5-0.03.0-1.0-2.92.61.9-0.7-1.8-2.02.4
Patch foraging time to switch 0 sec0.10.20.50.10.10.1-0.10.5-0.40.20.3-0.5-0.40.20.60.5-0.50.10.40.6-0.7-0.60.5
Patch foraging water rate 0 sec0.71.12.6-1.6-1.6-1.6-1.3-1.61.51.11.10.5-0.9-0.00.5-0.9-0.51.20.3-0.90.10.10.1
Patch foraging water rate 12 sec0.20.41.50.10.10.1-0.20.7-0.5-0.00.4-1.2-0.50.70.40.8-0.50.61.00.8-0.5-0.80.5
Patch foraging water rate 18 sec0.20.31.40.40.50.50.50.5-0.6-0.8-0.2-1.00.41.2-0.40.70.70.40.30.5-0.1-0.2-0.3
Patch foraging water rate 24 sec0.70.91.71.11.11.21.21.3-0.8-1.2-1.20.31.1-0.0-1.10.21.0-1.2-0.90.10.80.9-1.1
Patch foraging water rate 6 sec0.40.61.50.91.00.91.00.7-0.9-1.2-0.8-0.50.90.9-0.90.61.00.3-0.40.40.30.4-0.6
Seeking ratio, delayed vs. immediate footshock0.40.51.6-0.3-0.3-0.4-0.60.0-0.10.70.80.2-1.00.11.00.4-1.30.40.90.6-0.7-0.81.0
Distance traveled before self-admin0.70.82.51.01.01.11.10.6-0.6-0.8-1.20.10.9-0.7-0.9-0.20.7-1.6-0.5-0.10.91.0-0.8
Distance traveled after self-admin0.20.20.60.70.70.80.70.3-0.7-0.6-0.50.00.5-0.1-0.30.30.5-0.8-0.00.30.20.2-0.3
Extensor digitorum longus weight1.76.817.61.31.21.1-0.13.0-2.9-0.11.5-3.0-1.72.62.63.9-2.52.13.14.2-3.5-3.53.0
Bone: elastic displacement0.80.91.81.31.31.31.20.9-1.3-1.3-0.9-1.11.00.9-0.81.01.0-0.4-0.00.80.0-0.1-0.3
Bone: elastic work0.40.52.10.00.10.0-0.10.1-0.5-0.30.5-1.3-0.21.40.41.0-0.11.00.90.9-1.0-1.10.7
Bone: endosteal estimation9.420.445.6-6.3-6.3-6.2-5.4-5.46.85.83.75.4-3.5-4.92.5-5.5-3.1-0.6-1.0-4.91.00.9-0.4
Bone: endosteal perimeter8.918.439.0-5.9-5.9-5.8-5.2-4.86.25.63.65.3-3.6-4.82.6-5.1-3.3-1.0-1.0-4.40.80.8-0.1
Epididymis fat weight5.011.724.6-1.5-1.5-1.6-2.7-0.4-0.72.13.9-3.3-4.03.24.33.1-3.84.45.03.5-4.6-4.54.8
Delta time in closed arm before/after self-admin0.70.72.00.20.20.20.30.40.30.1-0.71.30.4-1.4-0.6-1.00.2-1.4-1.1-0.81.11.1-1.2
Delta time in open arm before/after self-admin1.41.32.61.31.31.41.60.3-0.9-1.5-1.6-0.41.60.2-1.60.11.6-1.1-1.0-0.11.01.1-0.8
Diff in mean of infusions in LGA sessions1.61.74.50.80.80.80.21.9-1.6-0.40.5-1.6-0.51.60.92.1-0.81.11.52.1-1.5-1.71.3
Delay discount exponential model param0.20.20.80.20.30.20.3-0.3-0.3-0.6-0.2-0.90.50.6-0.40.40.60.80.30.20.1-0.10.0
Extinction: sum of active levers before priming0.30.30.70.30.30.30.20.7-0.6-0.30.1-0.3-0.00.80.10.80.10.60.70.7-0.6-0.70.1
Active lever presses in extinction session 60.40.31.1-0.6-0.6-0.5-0.5-0.30.30.10.7-0.9-0.41.10.20.40.10.90.90.2-0.5-0.80.4
Bone: final force0.71.23.0-1.7-1.6-1.6-1.3-1.71.71.21.01.1-0.8-0.40.4-1.2-0.50.5-0.3-1.20.10.00.0
Bone: final moment0.81.23.1-1.7-1.6-1.6-1.3-1.81.81.10.91.2-0.7-0.50.2-1.3-0.30.4-0.5-1.30.30.2-0.2
Food consumed during 24 hour testing period1.82.18.2-0.6-0.5-0.6-0.7-1.0-0.3-0.21.3-2.2-0.72.90.81.60.02.71.81.2-1.9-1.91.6
Glucose0.30.52.61.01.01.00.61.6-1.1-0.4-0.40.40.1-0.20.20.7-0.5-1.0-0.20.9-0.3-0.2-0.0
Heart weight1.62.37.3-1.3-1.3-1.3-1.8-0.50.52.01.90.1-2.4-0.42.30.2-2.70.51.70.8-1.4-1.51.8
Delay discount hyperbolic model param0.10.10.80.00.10.00.0-0.4-0.2-0.40.1-0.90.20.6-0.10.40.40.80.50.2-0.1-0.20.2
Intermittent access intake day 1-15 change1.81.83.9-1.5-1.6-1.6-1.8-0.81.22.01.61.8-1.7-1.21.7-0.7-2.01.00.3-0.3-0.7-0.60.7
Intermittent access intake escalation1.81.74.5-1.4-1.4-1.5-1.7-0.81.12.01.51.6-1.7-1.31.7-0.6-2.10.80.4-0.1-0.8-0.60.9
Intermittent access intake escalation 23.03.06.2-2.2-2.2-2.2-2.2-1.81.92.51.92.2-2.0-1.41.9-1.3-2.01.00.2-0.8-0.7-0.60.7
Intermitt. access day 1 inactive lever presses1.81.93.6-1.7-1.7-1.7-1.9-1.51.11.61.9-0.3-1.80.11.6-0.1-1.60.81.40.1-1.3-1.31.4
Intermitt. access day 15 inactive lever presses1.51.63.1-0.9-1.0-1.0-1.4-0.90.21.21.6-0.7-1.70.61.80.7-1.61.41.50.9-1.5-1.61.6
Intermitt. access escalation Index1.00.91.60.70.70.71.00.7-0.1-0.9-1.20.31.2-0.7-1.3-0.51.2-1.1-1.2-0.71.31.3-1.1
Intermittent access day 1 total infusions0.20.21.4-0.6-0.5-0.5-0.3-1.20.60.10.2-0.4-0.10.3-0.1-0.40.2-0.0-0.1-0.50.00.0-0.0
Intermittent access day 15 total infusions2.22.54.7-2.1-2.1-2.1-2.1-2.01.82.21.81.2-1.9-0.91.7-1.0-1.91.00.4-0.7-0.8-0.70.9
Intermittent access terminal intake (last 3 days)2.93.26.5-2.6-2.5-2.6-2.4-2.62.42.31.91.5-1.8-1.01.5-1.5-1.61.10.2-1.3-0.5-0.40.6
Intermittent access total infusions1.82.06.2-2.1-2.1-2.1-1.8-2.51.91.71.50.5-1.4-0.51.0-1.2-1.00.80.3-1.1-0.4-0.40.5
Intermittent access day 1 locomotion2.42.64.7-2.0-2.0-2.1-2.2-1.81.52.02.1-0.1-2.1-0.01.8-0.4-1.91.01.4-0.2-1.4-1.21.5
Intermittent access day 15 total locomotion3.53.87.7-2.8-2.8-2.8-2.6-2.72.42.62.21.1-2.2-0.81.7-1.4-1.91.20.6-1.1-0.8-0.71.0
Intermittent access total locomotion5.96.712.9-3.6-3.6-3.6-3.6-3.22.83.33.30.3-3.2-0.22.6-1.1-2.81.91.9-0.8-1.7-1.61.8
Intermittent access standard deviation2.72.96.7-2.0-2.0-2.0-2.3-0.91.42.42.11.4-2.3-0.92.2-0.6-2.60.70.7-0.1-1.5-1.21.5
Left kidney weight0.92.66.0-0.3-0.3-0.4-1.10.3-0.80.81.7-1.5-1.81.32.11.7-2.21.52.52.1-2.0-2.32.1
Right kidney weight1.33.67.8-1.2-1.3-1.3-2.0-0.10.11.72.5-1.0-2.50.92.71.2-2.81.72.51.6-2.3-2.52.3
Cocaine induced anxiety0.50.51.20.50.60.60.80.5-0.1-0.7-0.90.21.0-0.2-1.0-0.31.1-0.6-0.9-0.50.80.8-1.1
Post-drug Anxiety0.91.02.11.21.21.21.31.5-0.7-0.9-1.30.31.1-0.5-1.1-0.10.8-1.3-1.1-0.10.90.9-1.1
Baseline Anxiety1.11.22.61.61.61.61.51.3-1.5-1.4-1.2-0.81.00.7-0.81.00.9-0.5-0.30.90.20.2-0.2
Tail length0.92.86.3-2.5-2.5-2.5-2.3-2.52.32.11.90.2-1.7-0.51.3-1.3-1.21.10.9-1.2-0.4-0.40.9
Length with tail1.55.310.5-2.9-3.0-3.0-3.2-2.42.33.22.9-0.1-3.2-0.92.6-1.0-2.91.12.0-0.5-1.3-1.41.9
Length without tail0.51.03.2-0.6-0.6-0.6-1.10.00.11.21.2-0.6-1.6-0.31.40.3-1.80.11.40.8-0.9-1.11.2
Times rat made contact with spout0.60.71.3-1.0-1.0-1.0-1.1-0.90.60.81.1-0.5-0.90.31.00.1-0.70.80.90.1-0.9-0.90.7
Lifetime Intake1.51.66.2-1.9-1.9-1.9-1.7-2.51.71.41.40.2-1.2-0.10.9-1.0-0.81.00.4-0.9-0.4-0.30.5
Liver weight, left0.61.02.50.50.50.50.90.20.1-0.8-1.20.21.3-0.7-1.4-0.81.4-1.0-1.2-1.01.31.3-1.6
Liver weight, right0.50.81.71.11.11.11.20.9-0.8-1.3-1.1-0.91.20.6-1.10.41.20.1-0.50.20.50.5-0.9
Locomotor activity1.52.44.5-1.6-1.6-1.6-1.8-1.50.71.12.1-0.9-1.61.61.70.8-1.21.91.80.7-2.0-2.11.5
Locomotor testing distance0.91.63.5-1.1-1.1-1.1-1.4-0.90.30.61.7-0.9-1.21.51.40.9-0.91.51.60.8-1.7-1.91.2
Locomotor testing rearing1.21.84.4-0.8-0.7-0.8-1.2-0.6-0.20.41.7-1.4-1.01.81.51.4-0.81.91.91.3-2.1-2.11.3
Locomotion in novel chamber0.30.41.31.00.90.90.71.1-1.0-0.6-0.5-0.80.30.2-0.20.70.1-0.60.10.80.1-0.1-0.0
Locomotion in novel chamber post-restriction0.30.41.5-0.8-0.8-0.8-0.5-1.21.00.60.30.4-0.3-0.30.0-0.90.1-0.0-0.4-0.90.30.3-0.1
Fecal boli incidents, locomotor time 10.50.52.9-0.1-0.1-0.1-0.20.60.20.80.01.7-0.5-1.50.4-0.6-1.0-1.3-0.3-0.20.20.2-0.2
Change in fecal boli incidents, locomotor task0.50.51.2-0.1-0.1-0.10.3-0.80.6-0.3-0.60.60.6-0.3-0.9-0.81.0-0.3-0.8-1.01.10.9-0.6
Time >=10cm from walls, locomotor time 10.30.30.90.80.80.80.70.8-0.6-0.6-0.7-0.10.5-0.4-0.40.20.3-1.0-0.50.20.30.4-0.3
Bouts of movement, locomotor time 11.11.22.4-0.1-0.1-0.2-0.60.4-0.60.41.0-1.1-1.11.21.31.3-1.21.21.51.4-1.5-1.51.5
Total resting periods, locomotor time 10.70.81.7-0.1-0.1-0.1-0.50.7-0.50.50.9-0.6-1.00.71.11.0-1.20.71.21.2-1.3-1.21.2
Rest time, locomotor task time 10.40.53.80.90.80.80.61.9-0.8-0.4-0.60.40.4-0.6-0.20.3-0.2-0.9-0.20.50.30.2-0.6
Distance moved, locomotor task time 10.60.72.5-0.2-0.1-0.2-0.2-0.9-0.2-0.30.5-1.6-0.21.60.30.80.31.60.70.6-0.9-0.81.1
Vertical activity count, locomotor time 10.50.51.9-0.4-0.4-0.4-0.4-1.20.10.10.5-1.1-0.41.00.40.40.01.40.60.3-0.8-0.71.0
Time >=10cm from walls, locomotor time 21.71.84.81.21.21.10.71.8-1.8-1.20.0-2.10.32.00.32.20.21.31.22.0-1.2-1.40.5
Bouts of movement, locomotor time 23.23.48.30.40.40.3-0.40.9-1.6-0.11.3-2.9-1.32.61.72.6-1.22.02.72.6-2.5-2.52.2
Total resting periods, locomotor time 22.62.86.20.50.40.4-0.31.0-1.60.01.1-2.5-1.22.11.62.3-1.41.42.42.5-2.2-2.22.0
Rest time, locomotor task time 23.43.98.22.52.52.52.52.2-1.6-1.6-2.61.11.9-1.7-1.8-0.11.0-2.9-1.80.12.12.0-1.8
Distance moved, locomotor task time 22.22.69.3-0.00.0-0.0-0.40.1-1.0-0.71.1-3.0-0.33.00.82.20.23.01.81.7-2.1-2.01.5
Vertical activity count, locomotor time 22.93.111.7-1.6-1.6-1.6-1.8-1.50.60.72.1-1.9-1.32.41.61.1-0.63.41.90.8-2.3-2.11.8
Light reinforcement 10.91.67.50.70.70.70.6-0.2-1.2-1.2-0.0-2.30.32.7-0.11.70.72.10.91.3-1.2-1.01.1
Light reinforcement 20.20.20.50.60.60.60.50.7-0.7-0.3-0.3-0.60.00.60.00.6-0.10.50.40.7-0.3-0.10.5
Bone: marrow area9.119.844.3-6.2-6.2-6.1-5.3-5.36.75.73.65.3-3.4-4.92.4-5.4-3.0-0.6-1.1-4.91.01.0-0.4
Bone: maximum diameter3.05.512.9-3.1-3.1-3.0-2.5-2.83.62.71.43.1-1.4-2.90.7-3.2-1.3-1.0-1.1-3.01.21.1-0.6
Bone: maximum force1.42.45.4-2.3-2.3-2.3-2.1-2.12.21.91.71.4-1.5-0.61.1-1.3-1.30.7-0.0-1.2-0.3-0.40.6
Bone: maximum moment1.42.45.6-2.4-2.3-2.3-2.1-2.22.31.91.61.5-1.5-0.71.0-1.4-1.20.6-0.2-1.4-0.2-0.20.4
Mean time between licks in bursts1.82.55.9-1.0-1.0-1.1-1.6-0.20.11.62.0-0.3-2.30.52.30.9-2.40.82.01.3-2.1-2.12.3
Mean num. licks in bursts0.20.21.20.10.10.10.2-0.0-0.3-0.50.0-1.10.21.0-0.20.50.50.50.50.3-0.5-0.40.2
Cd content in liver1.11.22.91.41.31.41.41.7-0.9-0.9-1.40.11.1-0.8-1.0-0.00.8-1.7-0.60.00.90.9-0.9
Co content in liver0.10.20.50.30.30.30.00.6-0.40.30.1-0.5-0.4-0.50.50.2-0.7-0.30.60.5-0.2-0.20.5
Cu content in liver0.30.30.8-0.2-0.2-0.20.1-0.50.60.1-0.40.60.4-0.7-0.6-0.80.4-0.2-0.7-0.90.80.8-0.7
Fe content in liver0.00.10.10.00.00.10.1-0.00.1-0.2-0.20.20.3-0.1-0.4-0.20.4-0.3-0.1-0.20.30.3-0.4
K content in liver1.91.94.20.20.30.30.9-0.20.7-0.5-1.51.41.3-1.4-1.7-1.61.3-1.1-2.0-1.72.02.0-1.9
Mg content in liver3.43.47.10.90.90.91.7-0.00.3-1.5-2.31.22.3-1.0-2.7-1.52.6-1.1-2.6-1.92.62.6-2.6
Mn content in liver3.03.47.40.70.80.81.60.00.5-1.4-2.11.22.3-1.0-2.7-1.62.5-2.2-2.4-2.02.52.5-2.7
Na content in liver1.31.33.20.80.80.81.20.5-0.1-0.9-1.50.91.3-0.8-1.5-0.81.1-1.5-1.8-0.81.51.5-1.5
Rb content in liver1.72.14.30.90.91.01.40.70.1-1.1-1.90.41.8-1.3-2.0-1.21.7-1.5-1.6-1.32.02.0-2.1
Se content in liver1.31.63.11.81.71.81.71.8-1.3-1.3-1.7-0.21.3-0.5-1.20.20.8-1.6-0.90.31.01.0-1.1
Sr content in liver0.80.81.6-0.5-0.5-0.5-0.9-0.2-0.10.81.1-0.3-1.20.41.30.6-1.30.81.20.8-1.2-1.21.1
Zn content in liver1.11.32.60.90.90.91.10.8-0.2-0.6-1.50.71.1-1.3-1.3-0.80.8-1.6-1.5-0.71.51.5-1.4
Bone: minimum diameter7.313.628.7-5.4-5.3-5.3-4.9-4.65.24.93.83.5-3.7-2.72.9-3.6-3.20.80.2-3.1-0.3-0.40.9
Time in familiar zone, hab. session 11.61.53.0-1.6-1.6-1.6-1.5-1.31.61.71.11.7-1.2-1.31.0-1.3-1.20.1-0.3-1.00.10.10.4
Time in novel zone, hab. session 10.90.91.91.11.11.11.11.0-1.2-1.3-0.7-1.41.01.2-0.71.11.00.20.20.8-0.2-0.1-0.4
Total zone transitions, hab. session 11.21.64.1-0.2-0.2-0.2-0.60.4-0.7-0.01.2-2.0-0.81.81.11.6-0.81.52.01.5-1.8-1.91.5
Total locomotion distance, hab. session 10.71.04.1-0.3-0.3-0.3-0.4-0.2-0.3-0.40.8-2.0-0.22.00.41.20.21.51.30.8-1.3-1.30.9
Locomotion velocity, hab. session 10.70.94.2-0.2-0.2-0.2-0.3-0.2-0.3-0.40.7-2.0-0.21.90.31.10.21.41.40.8-1.2-1.30.8
Time in familiar zone, hab. session 21.01.12.0-1.4-1.4-1.4-1.4-1.41.31.41.11.1-1.1-0.91.0-0.9-1.00.30.1-0.7-0.2-0.20.5
Time in novel zone, hab. session 21.71.73.61.41.41.51.71.2-0.9-1.8-1.7-0.81.80.5-1.80.21.9-0.8-0.9-0.11.11.0-1.3
Total zone transitions, hab. session 21.62.15.50.40.40.4-0.11.0-1.4-0.50.9-2.3-0.52.30.92.2-0.51.61.92.1-1.9-1.91.3
Total locomotion distance, hab. session 21.31.77.40.20.20.2-0.00.1-1.0-0.80.7-2.4-0.12.70.31.80.42.01.61.4-1.5-1.61.0
Locomotion velocity, hab. session 21.21.67.00.50.50.50.30.4-1.1-1.10.3-2.40.22.70.01.90.71.81.31.4-1.3-1.40.7
Novel to familiar place preference ratio1.91.94.0-1.9-1.9-1.9-1.9-1.41.82.01.51.1-1.7-1.11.4-1.2-1.70.20.3-0.9-0.3-0.30.6
Novelty place preference1.21.22.6-1.5-1.5-1.5-1.5-1.01.31.61.30.8-1.4-0.81.2-0.8-1.40.00.4-0.6-0.3-0.40.6
Time in novel zone, NPP test1.01.12.1-1.4-1.4-1.4-1.4-1.11.31.51.20.7-1.2-0.81.1-0.8-1.20.10.3-0.6-0.2-0.30.4
Total zone transitions, NPP test0.81.14.20.80.80.80.60.8-1.2-1.2-0.0-2.00.42.0-0.31.60.60.81.11.3-0.7-1.00.3
Total locomotion distance, NPP test0.71.04.80.30.30.30.5-0.4-0.5-1.3-0.1-2.00.82.2-0.81.01.51.60.70.4-0.3-0.5-0.1
Locomotion velocity, NPP test0.81.15.60.40.40.40.4-0.1-0.8-1.10.1-2.20.42.4-0.31.40.91.61.10.9-0.7-0.90.5
Intraocular pressure0.30.41.0-0.2-0.2-0.2-0.4-0.3-0.20.20.6-0.6-0.60.60.70.6-0.60.51.00.7-0.8-0.90.9
Delta distance traveled before/after self-admin0.50.52.20.60.60.60.5-0.0-0.9-1.0-0.2-0.90.61.5-0.21.10.80.80.30.8-0.5-0.60.3
Delta ambulatory time before/after self-admin0.10.10.7-0.3-0.3-0.2-0.0-0.60.3-0.20.00.30.40.6-0.3-0.10.80.3-0.3-0.40.0-0.1-0.3
Parametrial fat weight1.01.94.5-0.2-0.2-0.10.6-0.81.1-0.5-1.21.81.3-0.8-1.8-1.61.9-0.8-1.9-2.02.11.9-1.7
Pavlov. Cond. lever latency1.51.93.81.01.01.01.40.8-0.1-1.0-1.81.21.6-1.1-1.7-1.01.5-1.6-1.8-1.12.01.8-1.6
Pavlov. Cond. magazine entry latency1.41.84.6-1.9-1.9-1.9-1.8-2.11.51.71.60.1-1.6-0.21.4-0.7-1.21.20.6-0.5-0.9-0.70.9
Pavlov. Cond. change in total contacts1.82.03.6-1.6-1.5-1.6-1.8-1.60.91.41.9-0.7-1.70.61.70.2-1.51.71.40.4-1.6-1.41.4
Pavlov. Cond. index score1.41.83.2-1.6-1.6-1.6-1.8-1.71.01.51.8-0.4-1.70.31.6-0.0-1.41.41.10.1-1.4-1.21.2
Pavlov. Cond. latency score1.62.03.7-1.5-1.5-1.5-1.8-1.40.71.51.9-0.6-1.80.61.90.3-1.71.51.50.6-1.7-1.51.5
Pavlov. Cond. lever contacts2.02.45.3-0.7-0.7-0.8-1.3-0.4-0.30.91.8-1.5-1.71.32.01.4-1.71.82.21.6-2.3-2.12.0
Pavlov. Cond. magazine entry number0.91.13.11.51.51.51.41.8-1.4-1.3-1.1-0.31.10.4-0.90.80.8-0.6-0.10.70.40.2-0.4
Pavlov. Cond. intertrial magazine entries1.92.34.6-2.0-2.0-2.0-2.0-1.81.72.21.80.9-2.0-0.71.6-1.0-1.90.40.6-0.6-0.7-0.81.3
Pavlov. Cond. lever-magazine prob. diff.1.21.52.7-1.4-1.4-1.4-1.6-1.50.81.31.7-0.3-1.50.41.50.1-1.31.31.00.2-1.4-1.21.2
Pavlov. Cond. response bias0.81.02.0-1.3-1.3-1.3-1.4-1.40.91.11.3-0.5-1.20.21.1-0.1-1.01.00.7-0.1-0.9-0.80.8
Pavlov. Cond. lever latency0.70.91.91.01.01.00.71.3-1.4-0.7-0.2-1.30.21.10.11.40.10.61.21.3-0.7-0.70.7
Pavlov. Cond. magazine entry latency0.20.20.70.70.70.70.40.8-0.7-0.1-0.40.3-0.0-0.40.20.3-0.4-0.7-0.50.6-0.0-0.10.1
Pavlov. Cond. change in total contacts0.30.41.2-0.7-0.7-0.7-0.5-0.90.90.60.21.1-0.2-0.90.0-0.9-0.1-0.6-0.7-0.90.40.5-0.5
Pavlov. Cond. index score0.40.51.1-0.8-0.8-0.8-0.8-0.80.90.90.51.0-0.6-1.00.5-0.8-0.7-0.5-0.6-0.60.10.1-0.0
Pavlov. Cond. latency score0.40.51.3-0.6-0.6-0.6-0.6-0.60.80.80.31.1-0.5-1.20.4-0.8-0.6-0.7-0.8-0.60.30.2-0.2
Pavlov. Cond. lever contacts0.40.52.0-1.0-0.9-0.9-0.7-1.41.10.50.40.6-0.2-0.40.0-0.90.10.1-0.7-1.00.30.3-0.3
Pavlov. Cond. magazine entry number0.30.41.2-0.9-0.9-0.9-0.5-1.11.10.20.20.00.10.1-0.4-0.80.60.60.2-1.10.40.5-0.3
Pavlov. Cond. intertrial magazine entries1.41.87.0-2.1-2.0-2.0-1.4-2.62.20.91.00.9-0.30.3-0.1-1.40.61.1-0.2-1.80.20.3-0.2
Pavlov. Cond. lever-magazine prob. diff.0.30.41.2-0.6-0.7-0.6-0.6-0.60.80.80.31.1-0.5-1.00.4-0.8-0.6-0.7-0.8-0.60.20.2-0.2
Pavlov. Cond. response bias0.30.41.2-0.8-0.7-0.7-0.5-1.10.90.50.20.8-0.2-0.60.1-0.8-0.1-0.1-0.8-0.80.30.3-0.3
Time in closed arm before self-admin0.50.62.9-0.3-0.2-0.2-0.2-0.7-0.1-0.50.4-1.10.21.70.10.70.71.50.70.4-1.1-0.70.8
Time in closed arm after self-admin0.10.10.3-0.5-0.5-0.5-0.5-0.30.30.30.50.1-0.20.20.4-0.00.00.20.1-0.1-0.5-0.30.1
Time in open arm before self-admin1.61.76.2-0.1-0.2-0.3-1.00.9-0.61.31.3-0.6-1.9-0.32.21.0-2.50.41.51.6-1.3-1.71.5
Time in open arm after self-admin0.30.31.00.60.50.50.20.6-0.70.3-0.0-0.2-0.6-0.40.60.5-1.0-0.60.40.80.0-0.30.6
Bone: periosteal estimation6.413.129.0-5.3-5.2-5.2-4.6-4.75.44.63.33.8-3.1-3.12.2-4.0-2.60.3-0.5-3.60.30.30.2
Bone: periosteal perimeter4.06.613.1-3.5-3.5-3.5-3.4-2.63.43.62.63.1-2.8-2.52.3-2.5-2.9-0.4-0.1-1.9-0.2-0.30.7
Bone: post-yield work1.82.44.8-2.1-2.1-2.1-2.1-1.51.82.21.81.5-1.8-1.11.6-1.1-1.90.20.2-0.8-0.6-0.61.0
Progressive ratio test 1 active lever presses1.92.05.8-1.7-1.7-1.7-1.6-2.41.10.91.8-1.6-1.31.51.10.2-0.51.71.3-0.0-1.5-1.31.4
Progressive ratio test 1 breakpoint2.22.35.8-1.9-1.8-1.9-1.8-2.41.21.01.9-1.5-1.41.51.20.2-0.61.91.4-0.1-1.5-1.41.5
Progressive ratio test 1 inactive lever presses2.62.85.5-2.1-2.0-2.1-2.1-2.31.31.52.2-1.2-1.91.21.50.1-1.21.81.90.1-1.5-1.51.7
Progressive ratio test 2 active lever presses0.90.94.3-1.4-1.4-1.4-1.1-2.11.50.90.70.4-0.6-0.40.3-1.1-0.20.3-0.3-1.20.00.2-0.0
Progressive ratio test 2 breakpoint1.01.15.0-1.5-1.5-1.5-1.1-2.21.70.90.70.5-0.5-0.30.1-1.20.10.4-0.4-1.40.20.3-0.2
Progressive ratio test 2 inactive lever presses1.41.65.3-1.8-1.8-1.7-1.3-2.32.01.40.91.2-0.8-0.80.3-1.6-0.50.1-0.6-1.60.30.20.0
Incentive Sensitization - Responses1.01.02.3-0.2-0.2-0.10.3-0.80.80.1-0.71.50.7-1.3-0.9-1.40.8-1.1-1.4-1.41.31.3-1.3
Incentive Sensitization - Breakpoint1.11.22.3-0.1-0.1-0.10.4-0.80.80.0-0.81.50.7-1.4-1.0-1.40.9-1.3-1.5-1.51.51.4-1.5
Sum of active levers in priming session hrs 5-60.20.20.9-0.2-0.2-0.2-0.40.4-0.20.20.5-0.2-0.50.40.50.5-0.40.50.90.5-0.6-0.80.4
Progressive ratio0.20.31.70.50.50.50.40.8-0.30.1-0.50.3-0.0-1.0-0.1-0.2-0.4-1.3-0.60.00.40.4-0.1
Food seeking constrained by brief footshock0.70.83.1-1.3-1.3-1.3-1.0-1.81.50.80.70.8-0.3-0.60.1-1.10.20.3-0.2-1.20.10.2-0.6
Seeking ratio, punishment vs. effort0.50.62.8-1.1-1.1-1.1-0.9-1.71.00.30.80.0-0.10.70.2-0.20.51.30.5-0.6-0.4-0.3-0.2
Retroperitoneal fat weight4.113.524.2-2.5-2.6-2.7-3.7-1.60.22.84.7-2.5-4.43.24.72.6-3.94.84.92.9-4.7-4.84.8
Reaction time number correct0.81.22.51.11.11.11.30.9-0.5-1.1-1.40.51.3-0.6-1.4-0.31.1-1.6-1.3-0.41.41.2-1.2
Reaction time mean minus median0.00.00.10.0-0.0-0.0-0.10.3-0.00.20.10.4-0.2-0.30.3-0.0-0.40.2-0.00.1-0.0-0.10.1
Reaction time mean minus median AUC0.50.72.10.10.10.10.40.00.5-0.1-0.71.30.7-1.0-0.8-1.00.5-0.8-1.5-1.11.21.1-1.1
Reaction time num false alarms1.31.83.6-1.7-1.7-1.7-1.9-1.41.21.61.80.5-1.6-0.11.7-0.3-1.60.81.0-0.1-1.4-1.11.4
Reaction time num false alarms AUC1.52.14.2-2.1-2.0-2.0-2.1-1.81.71.81.80.9-1.5-0.31.5-0.7-1.40.80.8-0.6-1.1-0.81.1
Reaction time trials correct on left0.81.22.51.11.11.11.30.9-0.5-1.1-1.40.51.3-0.6-1.4-0.31.1-1.6-1.3-0.41.41.2-1.2
Reaction time trials on left0.81.22.31.01.01.01.20.8-0.4-1.0-1.40.61.2-0.6-1.4-0.41.1-1.5-1.3-0.51.41.2-1.2
Reaction time mean0.71.03.00.20.20.20.6-0.20.5-0.2-1.01.30.9-1.2-1.0-1.20.9-0.7-1.7-1.31.51.6-1.3
Reaction time mean AUC0.60.92.50.30.30.30.6-0.10.4-0.4-1.01.01.0-1.0-1.0-1.00.9-0.5-1.6-1.11.41.4-1.3
Median of all reaction times1.01.43.90.10.10.10.6-0.40.7-0.3-1.11.41.1-1.3-1.3-1.41.1-0.8-2.0-1.51.71.8-1.6
Reaction time omissions0.30.41.1-0.8-0.8-0.9-0.6-1.00.90.70.40.6-0.4-0.30.2-0.7-0.20.8-0.3-0.70.30.20.0
Reaction time false alarm rate2.02.85.3-2.1-2.1-2.1-2.3-1.61.42.02.30.4-1.9-0.02.1-0.3-1.91.41.3-0.1-1.7-1.41.6
Reaction time premature initiation rate1.72.34.4-1.4-1.5-1.5-1.8-1.20.71.72.00.4-2.00.42.10.3-2.11.91.20.7-1.6-1.71.6
Reaction time premature initiations0.30.41.1-0.7-0.7-0.7-0.8-0.70.40.90.80.8-0.9-0.10.9-0.1-1.00.80.10.1-0.4-0.60.4
Std. dev. reaction times0.30.51.3-0.2-0.2-0.20.1-0.30.60.3-0.41.10.3-1.1-0.4-1.00.3-0.4-1.0-1.01.01.0-0.8
Reaction time trials completed0.81.22.31.01.01.01.20.8-0.4-1.0-1.40.61.2-0.6-1.4-0.41.1-1.5-1.3-0.51.41.2-1.2
Reaction time trials AUC0.91.22.31.01.11.11.30.8-0.4-1.1-1.50.51.3-0.6-1.4-0.41.2-1.5-1.3-0.51.51.2-1.3
Run reversals in cocaine runway, females6.05.814.30.50.40.4-0.71.5-2.10.21.8-2.3-1.83.02.73.3-2.12.72.93.5-3.8-3.73.2
Run reversals in cocaine runway, males0.30.30.90.60.60.60.70.9-0.3-0.5-0.70.30.6-0.4-0.6-0.10.4-0.9-0.5-0.10.50.7-0.6
Latency to leave start box in cocaine runway1.61.75.71.51.51.51.31.1-1.8-1.8-0.7-2.41.11.8-0.51.81.20.20.61.5-0.7-0.50.1
Latency to leave start box in cocaine runway, F2.12.36.21.61.61.50.91.5-2.2-1.3-0.1-2.50.21.90.32.40.10.11.42.3-1.4-1.41.0
Latency to leave start box in cocaine runway, M0.60.62.40.50.60.60.80.0-0.4-1.1-0.7-1.61.10.9-0.90.41.40.6-0.1-0.00.10.4-0.6
Std. dev. time between licks in bursts0.70.93.30.60.60.60.40.5-1.1-0.70.2-1.2-0.01.80.21.50.20.90.81.3-1.2-1.11.0
Total sessions with >9 infusions0.10.10.8-0.2-0.2-0.2-0.2-0.90.20.10.2-0.6-0.30.30.10.0-0.20.10.10.0-0.2-0.10.4
Short access day 1 total inactive lever presses0.10.10.7-0.2-0.2-0.2-0.2-0.50.10.20.2-0.8-0.40.10.20.0-0.3-0.20.50.1-0.1-0.10.3
Short access day 10 total inactive lever presses0.91.02.9-1.1-1.1-1.1-1.3-0.40.71.41.30.6-1.4-0.51.3-0.2-1.70.80.80.1-0.6-0.70.9
Short access day 1 total infusions0.20.22.20.10.20.10.1-0.7-0.2-0.4-0.0-1.50.00.8-0.20.40.20.30.50.3-0.1-0.10.3
Short access day 10 total infusions3.23.67.7-2.4-2.3-2.4-2.4-2.81.61.72.4-1.0-2.01.31.7-0.0-1.32.51.8-0.1-1.7-1.71.7
Short access total infusions0.91.04.7-1.4-1.4-1.4-1.3-2.21.20.81.1-0.6-0.80.50.5-0.5-0.41.10.6-0.6-0.4-0.40.5
Short access day 1 locomotion1.21.33.1-1.1-1.1-1.1-1.0-1.80.60.41.2-1.6-0.91.70.60.5-0.31.81.30.2-1.2-1.01.1
Short access day 10 total locomotion5.15.710.7-3.1-3.1-3.1-3.3-2.42.23.03.2-0.2-3.10.12.6-0.6-2.71.82.3-0.2-1.9-1.72.1
Short access total locomotion4.14.27.4-2.3-2.3-2.3-2.5-2.11.31.92.7-1.6-2.51.42.10.4-2.02.62.60.4-2.1-1.92.1
One hour access (0.3 mA shock)1.92.26.6-1.9-1.9-1.9-1.5-2.62.21.70.92.1-0.9-1.50.6-1.9-0.7-0.0-0.9-1.70.50.5-0.3
Compulsive drug intake1.21.25.3-0.8-0.8-0.8-0.6-0.91.21.20.12.3-0.4-2.10.1-1.6-0.7-1.0-0.9-1.31.00.8-0.6
One hour access (shock baseline)0.40.51.3-1.0-1.0-1.0-0.9-1.10.80.70.90.1-0.70.30.6-0.2-0.40.90.1-0.3-0.5-0.40.4
Social response proportion0.40.51.6-0.9-0.9-0.9-0.7-1.20.90.70.51.3-0.5-0.30.3-0.7-0.20.6-0.4-0.70.20.1-0.2
Social responses2.02.55.6-2.1-2.1-2.1-2.1-2.41.41.62.10.3-1.70.81.6-0.2-1.22.11.1-0.2-1.4-1.31.3
Social time0.20.21.3-0.4-0.4-0.4-0.5-0.30.40.70.31.1-0.5-0.90.4-0.5-0.6-0.0-0.2-0.2-0.0-0.00.0
Soleus weight0.41.24.2-0.4-0.5-0.5-1.00.5-0.31.01.40.0-1.60.11.70.9-2.00.11.31.3-1.5-1.51.4
Bone: stiffness1.01.53.4-1.8-1.8-1.8-1.6-1.81.71.51.31.3-1.1-0.50.8-1.1-0.90.7-0.0-1.0-0.2-0.10.4
Tibialis anterior weight1.44.810.1-0.7-0.7-0.8-1.50.2-0.80.92.4-2.2-2.22.32.62.3-2.22.93.02.5-3.2-3.12.8
Time to tail flick, vehicle, before self-admin0.50.53.0-0.1-0.1-0.1-0.10.10.40.7-0.20.9-0.3-1.7-0.0-0.9-0.5-1.5-0.3-0.60.70.6-0.4
Time to tail flick, vehicle, after self-admin1.21.25.6-0.7-0.7-0.6-0.2-0.71.30.7-0.32.40.1-1.6-0.4-1.70.2-1.5-1.3-1.60.81.3-0.7
Time to tail flick, test, before self-admin1.00.92.9-1.1-1.1-1.1-0.9-0.21.31.40.61.5-0.8-1.70.4-1.3-0.8-0.6-0.2-1.10.50.3-0.3
Time to tail flick, test, after self-admin1.31.33.3-1.5-1.4-1.4-1.0-1.11.81.20.51.6-0.5-1.40.1-1.8-0.30.0-0.5-1.70.60.9-0.4
Delta time to tail flick, vehicle, before/after SA1.51.44.4-1.0-0.9-0.9-0.2-1.51.60.1-0.41.80.8-0.7-1.1-1.71.2-0.3-1.6-2.11.11.5-1.1
Delta time to tail flick, test, before/after SA0.80.72.5-0.5-0.5-0.5-0.2-0.51.00.4-0.31.60.2-1.4-0.4-1.40.1-0.5-1.1-1.30.81.2-0.8
Tibia length0.72.04.8-1.2-1.2-1.2-1.7-0.50.51.71.8-0.7-2.1-0.11.90.2-2.20.61.80.6-1.4-1.51.9
Ambulatory time before self-admin0.60.61.31.11.11.11.10.8-0.8-0.8-1.0-0.40.8-0.3-0.80.20.6-1.1-0.20.20.70.7-0.6
Ambulatory time after self-admin0.30.30.90.70.70.70.70.2-0.6-0.8-0.6-0.30.70.5-0.50.41.0-0.40.00.20.20.2-0.3
Bone: tissue strength1.61.52.81.61.61.71.71.3-1.3-1.6-1.6-0.41.50.2-1.40.51.4-1.1-1.00.30.70.8-1.0
Total heroin consumption0.10.10.2-0.4-0.4-0.4-0.3-0.20.50.30.20.3-0.1-0.30.0-0.40.00.10.2-0.40.20.2-0.4
Bone: trabecular number1.21.83.7-0.00.00.10.7-0.50.9-0.6-1.21.71.4-1.0-1.8-1.51.6-1.5-1.9-1.81.91.9-1.8
Bone: trabecular spacing0.50.61.40.10.10.1-0.30.4-0.60.10.6-1.1-0.60.70.91.0-0.61.01.21.1-1.1-1.10.8
Bone: trabecular thickness0.70.92.0-1.3-1.3-1.3-1.0-1.41.41.10.71.3-0.7-0.80.4-1.2-0.6-0.0-0.3-1.10.30.20.3
Bone: trabecular tissue density0.10.10.40.30.30.20.2-0.1-0.4-0.1-0.0-0.3-0.20.60.20.4-0.20.40.20.5-0.2-0.30.6
Water consumed over 24 hours1.01.25.80.20.20.2-0.0-0.3-0.8-0.70.5-1.9-0.12.40.31.50.41.61.01.2-1.4-1.51.0
Number of responses in last shaping day0.80.81.9-0.4-0.4-0.4-0.7-0.1-0.20.41.1-1.4-1.00.91.00.9-1.00.81.21.0-1.4-1.11.2