Hub : Genes

Ctxn1

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 IL gene expression Ctxn1 0.23 0.13 6.4e-05 0.14 0.17 0.19 0.14 3.7e-04 7.1e-05 2.4e-05 3.8e-04
2 BLA gene expression Ctxn1 0.37 0.16 2.0e-14 0.25 0.27 0.26 0.27 2.2e-13 6.5e-15 3.2e-14 9.2e-15
3 Liver gene expression Ctxn1 0.12 0.07 1.9e-06 0.03 0.03 0.04 0.03 5.0e-04 4.8e-04 8.6e-05 1.5e-04
4 PL gene expression Ctxn1 0.21 0.09 0.0e+00 0.27 0.28 0.28 0.28 3.4e-29 1.3e-30 1.4e-30 2.2e-30
5 Brain gene expression Ctxn1 0.49 0.14 0.0e+00 0.54 0.57 0.57 0.57 5.4e-59 4.8e-64 9.9e-65 1.4e-64
6 NAcc gene expression Ctxn1 0.15 0.07 0.0e+00 0.18 0.18 0.19 0.18 5.4e-20 2.4e-20 3.6e-21 5.8e-21
7 PL mRNA stability Ctxn1 0.03 0.02 2.8e-03 0.02 0.02 0.01 0.01 4.6e-03 4.9e-03 1.7e-02 9.2e-03
8 Brain mRNA stability Ctxn1 0.03 0.02 1.5e-03 0.03 0.03 0.03 0.03 4.0e-04 1.6e-03 1.5e-03 7.3e-04
9 OFC gene expression Ctxn1 0.15 0.09 7.3e-04 0.17 0.16 0.14 0.16 9.0e-05 1.3e-04 2.6e-04 1.4e-04

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9
Bone: apparent density0.71.38.1-2.8-0.30.40.2-0.4-0.7-0.6-1.2-0.7
Area under the delay curve1.31.42.0-0.11.2-1.41.2-1.2-1.3-1.0-1.4-1.2
BMI with tail0.72.27.6-2.70.7-0.41.0-1.1-1.3-1.0-2.1-1.4
BMI without tail0.30.73.7-1.9-0.80.9-0.40.3-0.10.1-0.7-0.4
Body weight1.45.833.4-5.8-2.52.7-1.51.00.30.6-1.2-0.2
Weight adjusted by age0.40.50.80.9-0.80.8-0.80.70.50.60.20.5
Bone surface0.81.49.4-3.1-0.30.50.2-0.4-0.6-0.6-1.3-0.5
Bone volume1.22.09.2-3.00.4-0.20.8-1.0-1.2-1.1-1.7-1.0
Breakpoint value in progressive ratio session2.22.43.2-1.81.4-1.41.5-1.6-1.6-1.7-1.4-1.5
Number of licking bursts8.710.211.72.3-3.23.3-3.33.33.33.13.43.3
Context. condit. distance diff. score2.83.412.2-3.50.9-0.91.3-1.6-1.7-1.8-1.7-1.9
Locomotion velocity, session 10.30.40.50.50.7-0.70.6-0.6-0.6-0.5-0.7-0.5
Locomotion distance, session 10.20.31.01.00.6-0.70.4-0.4-0.4-0.2-0.3-0.6
Locomotion velocity, session 20.30.41.31.1-0.50.4-0.60.60.60.70.50.3
Locomotion distance, session 20.20.32.01.4-0.1-0.2-0.20.30.20.20.7-0.1
Locomotion velocity, session 30.91.11.6-1.30.8-0.80.9-1.0-1.1-1.0-1.2-1.3
Locomotion distance, session 30.10.10.2-0.10.1-0.20.2-0.3-0.3-0.3-0.1-0.4
Stereotopy head waving bouts, day 30.20.20.6-0.4-0.80.7-0.60.50.30.3-0.1-0.1
Stereotopy head waving duration, day 30.00.00.10.2-0.00.1-0.10.10.10.2-0.2-0.2
Locomotion velocity, session 70.10.10.20.30.4-0.50.3-0.3-0.2-0.1-0.1-0.4
Locomotion distance, session 70.10.20.3-0.60.4-0.50.4-0.5-0.4-0.5-0.0-0.5
Stereotopy head waving bouts, day 70.40.40.70.20.7-0.80.7-0.6-0.6-0.6-0.5-0.8
Stereotopy head waving duration, day 70.10.10.80.90.4-0.40.3-0.2-0.1-0.1-0.1-0.2
Locomotion velocity, session 80.00.00.1-0.3-0.20.1-0.20.10.10.2-0.1-0.1
Locomotion distance, session 80.50.73.6-1.90.2-0.30.4-0.6-0.6-0.6-0.6-0.9
Degree of sensitization distance0.10.10.50.30.00.1-0.10.20.40.30.70.5
Degree of sensitization stereotypy0.30.40.6-0.00.7-0.70.7-0.6-0.6-0.6-0.6-0.6
Conditioned locomotion0.80.91.4-1.00.8-0.80.9-0.8-1.0-0.9-1.2-1.1
Cocaine response after cond. corrected0.10.10.40.30.10.1-0.00.10.10.4-0.70.5
Cocaine response after cond. not corrected1.01.12.6-0.81.1-0.91.1-1.0-1.0-0.8-1.6-0.6
Cocaine response before conditioning4.25.16.4-2.32.1-2.12.3-2.4-2.3-2.5-1.9-2.4
Saline control response1.72.23.40.7-1.81.8-1.71.51.41.11.71.2
Bone: connectivity density0.81.28.1-2.8-0.91.0-0.40.2-0.1-0.2-0.7-0.2
Bone: cortical apparent density0.10.10.4-0.20.5-0.60.4-0.3-0.3-0.1-0.2-0.5
Bone: cortical area0.71.13.7-1.90.4-0.30.7-0.8-1.0-0.9-1.4-0.9
Bone: cortical porosity0.10.10.70.8-0.20.2-0.20.20.20.10.20.2
Bone: cortical porosity0.20.20.80.90.5-0.40.4-0.4-0.4-0.5-0.3-0.1
Bone: cortical thickness0.40.63.7-1.90.00.00.3-0.4-0.6-0.5-1.0-0.5
Bone: cortical thickness0.30.30.7-0.9-0.70.7-0.50.40.40.20.50.4
Bone: cortical tissue density0.10.10.3-0.10.5-0.60.4-0.3-0.2-0.1-0.1-0.5
Condit. Reinf. active minus inactive responses0.70.71.4-0.41.2-1.01.1-1.0-0.8-0.9-0.6-0.4
Condit. Reinf. active-inactive response ratio0.90.91.5-0.61.2-1.01.1-1.1-1.0-1.0-0.9-0.6
Condit. Reinf. active responses0.81.01.5-0.51.2-1.11.2-1.2-1.0-1.2-0.6-0.8
Condit. Reinf. inactive responses0.50.60.90.20.8-1.00.8-0.8-0.8-0.9-0.4-1.0
Incentive salience index mean1.31.62.2-0.91.5-1.41.5-1.4-1.2-1.4-0.9-1.0
Condit. Reinf. lever presses1.62.22.9-1.31.5-1.51.6-1.6-1.5-1.7-1.2-1.4
Condit. Reinf. active minus inactive responses0.30.31.6-1.3-0.50.6-0.30.30.30.10.50.5
Condit. Reinf. active-inactive response ratio0.30.30.6-0.1-0.60.6-0.50.50.50.30.70.8
Condit. Reinf. active responses0.60.95.6-2.40.3-0.20.6-0.7-0.6-0.9-0.1-0.4
Condit. Reinf. inactive responses0.91.14.0-2.00.7-0.70.9-1.0-0.9-1.2-0.4-1.0
Condit. Reinf. lever presses1.72.35.4-2.31.2-1.21.4-1.5-1.5-1.6-1.2-1.5
Condit. Reinf. lever reinforcers received0.50.74.1-2.00.4-0.30.6-0.7-0.6-0.9-0.1-0.4
Conditioned reinforcement - actives2.12.14.1-0.9-2.01.9-1.61.51.31.21.21.2
Conditioned reinforcement - inactives1.41.52.10.3-1.51.3-1.41.21.21.31.31.3
Conditioned locomotion0.40.42.5-1.6-0.80.7-0.40.20.0-0.10.3-0.1
Patch foraging indifference point 0 sec0.00.10.3-0.6-0.20.1-0.10.10.20.10.4-0.1
Patch foraging indifference point AUC0.40.50.8-0.8-0.80.9-0.70.60.50.30.60.6
Delay disc. indifference point, 0s delay0.10.20.7-0.30.3-0.30.3-0.4-0.20.3-0.8-0.3
Delay disc. indifference point, 16s delay0.20.20.3-0.20.4-0.60.4-0.3-0.6-0.4-0.5-0.5
Delay disc. indifference point, 2s delay4.75.27.2-0.72.7-2.62.5-2.6-2.3-2.0-2.4-2.1
Delay disc. indifference point, 24s delay0.00.00.10.20.0-0.1-0.00.10.10.20.30.0
Delay disc. indifference point, 4s delay2.62.73.7-0.81.9-1.91.8-1.9-1.7-1.4-1.6-1.7
Delay disc. indifference point, 8s delay0.90.91.30.20.9-1.10.9-0.8-1.1-1.0-1.0-1.1
Indifference point function ln k0.30.42.31.5-0.30.3-0.40.40.30.20.50.4
Indifference point function log k0.30.42.31.5-0.30.3-0.40.40.30.20.50.4
Patch foraging total patch changes 0 sec0.10.10.4-0.6-0.30.1-0.10.10.2-0.00.5-0.1
Patch foraging total patch changes 12 sec0.10.10.5-0.7-0.0-0.10.1-0.1-0.2-0.2-0.2-0.3
Patch foraging total patch changes 18 sec0.50.61.1-0.3-0.70.9-0.70.70.80.51.10.9
Patch foraging total patch changes 24 sec0.40.42.1-1.50.3-0.50.4-0.5-0.4-0.80.2-0.6
Patch foraging total patch changes 6 sec0.10.10.5-0.7-0.20.0-0.1-0.0-0.1-0.20.1-0.4
Patch foraging time to switch 0 sec0.50.71.60.61.3-1.21.0-0.8-0.6-0.0-1.0-0.6
Patch foraging water rate 0 sec0.61.02.3-0.5-1.51.4-1.21.00.70.31.00.7
Patch foraging water rate 12 sec0.00.00.20.2-0.20.0-0.0-0.0-0.2-0.5-0.0-0.3
Patch foraging water rate 18 sec0.40.51.10.20.6-0.90.7-0.7-0.7-1.0-0.4-1.1
Patch foraging water rate 24 sec0.10.20.50.2-0.70.6-0.50.40.2-0.20.20.0
Patch foraging water rate 6 sec0.60.81.7-1.00.6-0.70.8-0.8-1.0-1.3-0.8-1.0
Seeking ratio, delayed vs. immediate footshock1.82.13.71.9-0.80.9-1.11.31.51.41.81.9
Distance traveled before self-admin0.60.61.0-0.41.0-0.90.9-0.9-0.8-0.9-0.2-0.8
Distance traveled after self-admin0.10.21.1-1.10.1-0.10.2-0.2-0.2-0.30.1-0.2
Extensor digitorum longus weight0.72.919.9-4.5-0.50.70.3-0.6-1.0-1.2-1.3-1.0
Bone: elastic displacement0.20.20.5-0.1-0.70.5-0.60.50.40.40.50.0
Bone: elastic work0.40.52.0-1.4-1.00.8-0.60.40.20.20.0-0.4
Bone: endosteal estimation0.40.81.6-0.3-1.21.3-1.10.90.80.70.70.7
Bone: endosteal perimeter0.30.62.0-1.40.2-0.10.4-0.6-0.7-0.9-0.8-0.7
Epididymis fat weight1.84.26.0-2.41.7-1.91.9-2.0-2.1-2.1-1.8-2.4
Delta time in closed arm before/after self-admin0.10.10.5-0.5-0.10.2-0.1-0.10.2-0.20.70.2
Delta time in open arm before/after self-admin1.61.62.70.91.6-1.51.4-1.0-1.3-1.0-1.3-1.0
Diff in mean of infusions in LGA sessions1.01.11.6-0.80.9-1.01.0-1.1-1.1-1.3-0.8-1.2
Delay discount exponential model param1.92.02.70.2-1.51.6-1.51.41.61.31.51.4
Extinction: sum of active levers before priming1.61.62.1-0.81.4-1.41.4-1.4-1.2-1.2-1.2-1.1
Active lever presses in extinction session 60.40.41.6-1.30.2-0.30.4-0.4-0.5-0.5-0.7-0.5
Bone: final force0.61.02.1-0.7-1.41.4-1.11.00.80.80.50.8
Bone: final moment0.71.12.1-0.5-1.51.5-1.21.10.90.90.60.8
Food consumed during 24 hour testing period1.11.32.21.2-1.01.2-1.11.01.10.91.21.5
Glucose0.00.00.10.20.2-0.20.10.00.10.3-0.0-0.1
Heart weight0.81.23.80.6-1.30.9-1.11.01.00.71.90.8
Delay discount hyperbolic model param1.81.92.70.1-1.51.7-1.51.51.51.21.51.4
Intermittent access intake day 1-15 change1.91.93.10.2-1.81.7-1.61.41.31.41.11.4
Intermittent access intake escalation1.01.01.9-0.1-1.41.2-1.21.00.90.90.80.9
Intermittent access intake escalation 20.20.20.4-0.0-0.60.5-0.50.50.40.40.60.5
Intermitt. access day 1 inactive lever presses1.71.83.90.1-1.41.4-1.31.21.41.12.01.4
Intermitt. access day 15 inactive lever presses0.20.30.60.8-0.30.3-0.40.40.50.80.20.6
Intermitt. access escalation Index0.70.61.00.20.8-0.80.8-0.8-0.9-1.0-0.7-0.9
Intermittent access day 1 total infusions0.70.81.3-0.11.0-1.11.0-1.0-0.9-1.0-0.6-0.9
Intermittent access day 15 total infusions0.00.00.1-0.2-0.2-0.0-0.0-0.1-0.2-0.1-0.1-0.2
Intermittent access terminal intake (last 3 days)0.00.00.00.10.1-0.20.1-0.2-0.2-0.1-0.1-0.1
Intermittent access total infusions0.50.60.9-0.20.8-0.90.8-0.9-0.8-0.7-0.7-0.7
Intermittent access day 1 locomotion4.44.65.9-0.22.3-2.42.3-2.3-2.3-2.2-2.0-2.3
Intermittent access day 15 total locomotion1.51.62.5-0.61.0-1.21.1-1.4-1.5-1.6-1.1-1.5
Intermittent access total locomotion2.52.93.9-0.51.8-2.01.8-1.9-1.8-1.9-1.3-1.8
Intermittent access standard deviation0.80.91.30.5-1.01.0-1.00.90.91.10.71.1
Left kidney weight1.54.19.2-2.5-3.02.9-2.31.81.31.20.81.1
Right kidney weight1.33.67.4-2.3-2.72.7-2.11.71.31.30.80.8
Cocaine induced anxiety3.33.84.4-1.32.0-1.92.0-2.0-2.1-2.1-2.0-1.9
Post-drug Anxiety3.23.55.50.32.3-2.22.1-1.9-1.9-1.7-2.0-1.6
Baseline Anxiety0.30.41.61.30.8-0.80.4-0.2-0.10.2-0.30.1
Tail length0.92.77.9-2.8-2.42.3-1.71.30.80.80.30.2
Length with tail2.07.525.2-5.0-3.73.5-2.62.11.41.40.40.7
Length without tail1.02.215.2-3.9-1.21.1-0.50.2-0.2-0.0-1.1-0.5
Times rat made contact with spout0.80.91.31.1-1.01.2-1.00.90.90.70.81.0
Lifetime Intake0.30.30.5-0.00.6-0.70.6-0.6-0.5-0.4-0.6-0.5
Liver weight, left0.61.01.6-0.5-1.21.3-1.11.01.00.91.00.7
Liver weight, right0.40.63.9-2.0-0.70.8-0.30.0-0.2-0.2-0.3-0.2
Locomotor activity0.20.31.2-1.1-0.80.6-0.50.30.3-0.00.3-0.3
Locomotor testing distance0.20.40.8-0.1-0.90.7-0.80.60.60.40.60.1
Locomotor testing rearing0.10.10.50.70.2-0.20.1-0.1-0.1-0.2-0.1-0.2
Locomotion in novel chamber0.81.02.9-0.1-1.00.9-0.90.80.90.51.71.3
Locomotion in novel chamber post-restriction0.20.30.6-0.6-0.80.7-0.50.40.2-0.10.60.2
Fecal boli incidents, locomotor time 10.20.31.7-1.3-0.40.4-0.2-0.00.0-0.30.5-0.1
Change in fecal boli incidents, locomotor task0.40.42.11.5-0.20.1-0.40.60.50.80.00.3
Time >=10cm from walls, locomotor time 12.52.63.7-0.41.9-1.71.8-1.8-1.6-1.6-1.6-1.4
Bouts of movement, locomotor time 10.40.40.8-0.7-0.90.9-0.70.50.40.20.60.5
Total resting periods, locomotor time 10.20.30.6-0.8-0.70.7-0.50.30.20.00.50.4
Rest time, locomotor task time 10.20.20.7-0.8-0.0-0.10.1-0.2-0.4-0.4-0.4-0.6
Distance moved, locomotor task time 10.10.10.30.50.1-0.10.00.10.20.10.30.2
Vertical activity count, locomotor time 10.20.20.40.0-0.60.5-0.40.50.40.30.40.6
Time >=10cm from walls, locomotor time 22.22.33.2-1.51.3-1.21.4-1.6-1.6-1.5-1.8-1.7
Bouts of movement, locomotor time 20.50.51.8-1.30.2-0.20.4-0.6-0.9-0.9-0.7-0.6
Total resting periods, locomotor time 20.40.41.4-1.20.1-0.00.2-0.4-0.8-0.8-0.6-0.5
Rest time, locomotor task time 20.80.91.5-0.11.0-1.00.9-0.9-1.0-1.1-0.9-1.2
Distance moved, locomotor task time 22.12.43.01.1-1.61.4-1.61.61.71.71.61.5
Vertical activity count, locomotor time 23.23.55.6-0.0-2.42.2-2.12.01.91.91.71.6
Light reinforcement 10.40.71.3-0.41.0-1.11.0-0.9-0.7-0.7-0.8-1.0
Light reinforcement 20.50.71.10.7-0.70.6-0.70.91.01.01.00.7
Bone: marrow area0.40.91.8-0.2-1.31.3-1.11.00.90.70.80.8
Bone: maximum diameter0.20.41.8-1.4-0.20.30.1-0.2-0.4-0.4-0.9-0.3
Bone: maximum force0.30.51.7-1.3-1.01.0-0.60.50.30.20.10.3
Bone: maximum moment0.30.51.1-1.1-1.01.0-0.70.60.40.30.30.3
Mean time between licks in bursts0.30.41.21.10.7-0.90.6-0.4-0.5-0.4-0.3-0.6
Mean num. licks in bursts2.63.24.0-1.01.8-1.71.8-2.0-1.9-1.9-2.0-1.8
Cd content in liver0.50.52.31.5-0.30.2-0.40.50.50.21.20.3
Co content in liver1.82.12.81.5-1.41.5-1.41.31.51.31.51.7
Cu content in liver0.20.30.5-0.60.4-0.50.5-0.5-0.5-0.7-0.4-0.3
Fe content in liver3.33.98.0-2.81.3-1.31.7-1.8-2.1-2.2-2.1-2.1
K content in liver0.50.50.9-0.90.7-0.50.8-0.7-0.7-0.8-0.6-0.4
Mg content in liver0.10.10.2-0.2-0.40.5-0.30.30.30.20.30.4
Mn content in liver1.01.22.01.4-0.70.8-0.91.01.11.11.11.3
Na content in liver0.30.30.7-0.60.4-0.50.4-0.5-0.6-0.5-0.7-0.8
Rb content in liver1.92.33.8-0.61.9-1.81.8-1.7-1.5-1.5-1.3-1.1
Se content in liver5.66.910.2-3.22.3-2.22.5-2.6-2.7-2.6-2.8-2.5
Sr content in liver2.52.23.21.0-1.61.5-1.71.61.61.81.31.2
Zn content in liver1.31.42.3-1.0-1.51.5-1.31.11.11.10.91.1
Bone: minimum diameter0.10.10.30.6-0.20.3-0.20.30.30.20.20.4
Time in familiar zone, hab. session 10.30.31.51.2-0.10.2-0.30.30.40.50.00.5
Time in novel zone, hab. session 10.20.21.3-1.1-0.20.2-0.10.10.0-0.00.2-0.1
Total zone transitions, hab. session 10.40.51.0-0.60.9-1.00.9-0.8-0.6-0.8-0.2-0.4
Total locomotion distance, hab. session 11.72.43.2-1.81.6-1.61.6-1.5-1.4-1.4-1.3-1.4
Locomotion velocity, hab. session 11.82.63.4-1.41.8-1.81.8-1.6-1.5-1.5-1.3-1.6
Time in familiar zone, hab. session 20.10.10.3-0.30.4-0.20.3-0.3-0.2-0.1-0.5-0.1
Time in novel zone, hab. session 20.10.10.20.30.2-0.30.1-0.1-0.2-0.20.2-0.4
Total zone transitions, hab. session 20.91.11.40.9-1.21.1-1.11.11.01.10.91.0
Total locomotion distance, hab. session 20.00.00.10.2-0.1-0.0-0.10.10.10.10.10.0
Locomotion velocity, hab. session 20.10.10.20.2-0.30.2-0.30.30.30.30.40.3
Novel to familiar place preference ratio0.80.81.21.0-0.80.7-0.90.80.90.91.10.7
Novelty place preference0.60.61.41.2-0.60.5-0.70.70.80.81.10.6
Time in novel zone, NPP test0.50.51.01.0-0.60.5-0.70.60.70.80.90.5
Total zone transitions, NPP test0.00.00.0-0.1-0.10.0-0.00.0-0.0-0.10.0-0.1
Total locomotion distance, NPP test1.92.63.4-1.51.5-1.61.6-1.6-1.7-1.6-1.6-1.8
Locomotion velocity, NPP test1.21.82.2-1.31.1-1.31.3-1.3-1.4-1.5-1.2-1.5
Intraocular pressure0.50.83.8-2.00.2-0.10.5-0.7-0.7-0.9-0.6-0.7
Delta distance traveled before/after self-admin0.80.81.3-0.1-1.11.0-1.01.00.91.00.70.9
Delta ambulatory time before/after self-admin0.20.20.30.2-0.50.5-0.40.50.40.50.20.5
Parametrial fat weight1.02.03.00.6-1.41.4-1.41.61.61.71.11.5
Pavlov. Cond. lever latency1.11.52.70.3-1.61.6-1.51.41.11.20.70.9
Pavlov. Cond. magazine entry latency0.00.00.1-0.1-0.00.10.0-0.1-0.1-0.2-0.1-0.3
Pavlov. Cond. change in total contacts1.01.01.5-0.91.2-1.11.2-1.1-0.9-1.0-0.8-0.8
Pavlov. Cond. index score0.70.91.2-0.71.0-0.91.0-1.1-1.0-1.0-0.8-1.0
Pavlov. Cond. latency score0.91.21.5-0.71.2-1.11.2-1.2-1.1-1.2-0.9-1.0
Pavlov. Cond. lever contacts1.31.52.4-0.51.6-1.51.4-1.4-1.1-1.2-0.8-1.0
Pavlov. Cond. magazine entry number0.40.50.90.6-0.50.5-0.60.80.81.00.80.9
Pavlov. Cond. intertrial magazine entries0.20.21.41.20.1-0.3-0.00.10.10.10.5-0.0
Pavlov. Cond. lever-magazine prob. diff.0.70.81.1-0.71.0-0.91.0-1.0-0.9-1.0-0.8-1.0
Pavlov. Cond. response bias0.70.91.2-0.90.9-0.80.9-1.0-1.0-1.1-0.8-1.0
Pavlov. Cond. lever latency1.41.92.41.3-1.41.4-1.41.41.41.61.11.4
Pavlov. Cond. magazine entry latency2.02.33.4-0.81.8-1.71.8-1.7-1.5-1.5-1.3-1.3
Pavlov. Cond. change in total contacts0.40.60.9-0.40.7-0.80.8-0.8-0.9-0.9-0.8-0.8
Pavlov. Cond. index score1.72.22.7-1.01.6-1.61.6-1.6-1.5-1.7-1.2-1.3
Pavlov. Cond. latency score1.82.32.8-1.11.7-1.61.7-1.6-1.6-1.7-1.2-1.3
Pavlov. Cond. lever contacts2.73.74.3-1.81.9-1.92.0-2.0-2.0-2.1-1.7-1.9
Pavlov. Cond. magazine entry number1.11.42.20.5-1.51.4-1.41.31.21.30.90.9
Pavlov. Cond. intertrial magazine entries0.50.61.00.3-1.00.9-1.00.80.80.61.00.6
Pavlov. Cond. lever-magazine prob. diff.1.51.92.4-0.81.5-1.51.5-1.5-1.4-1.5-1.1-1.2
Pavlov. Cond. response bias3.64.95.8-1.92.3-2.32.4-2.3-2.3-2.4-1.9-2.1
Time in closed arm before self-admin1.21.42.6-0.1-1.61.4-1.41.41.11.20.71.0
Time in closed arm after self-admin0.90.91.7-0.7-1.21.1-1.00.80.90.51.30.8
Time in open arm before self-admin0.00.00.10.1-0.20.2-0.2-0.10.10.10.20.2
Time in open arm after self-admin0.60.71.40.80.9-0.80.7-0.6-0.9-0.5-1.2-0.7
Bone: periosteal estimation0.20.31.6-1.3-0.70.8-0.40.30.10.0-0.20.1
Bone: periosteal perimeter1.32.23.5-1.91.0-1.01.3-1.4-1.6-1.7-1.6-1.5
Bone: post-yield work0.81.14.0-2.00.7-0.60.9-0.9-0.9-1.1-0.8-0.8
Progressive ratio test 1 active lever presses0.60.71.1-0.2-1.01.0-0.90.80.80.80.60.9
Progressive ratio test 1 breakpoint0.91.01.4-0.2-1.21.2-1.01.01.01.10.71.0
Progressive ratio test 1 inactive lever presses1.71.93.5-0.4-1.61.6-1.41.21.41.11.91.3
Progressive ratio test 2 active lever presses0.40.41.0-0.7-1.00.8-0.70.50.40.40.50.4
Progressive ratio test 2 breakpoint0.30.40.8-0.4-0.90.7-0.70.60.50.40.60.5
Progressive ratio test 2 inactive lever presses1.01.22.5-0.3-1.61.4-1.30.90.90.61.40.7
Incentive Sensitization - Responses0.10.10.2-0.10.1-0.20.2-0.3-0.3-0.4-0.0-0.2
Incentive Sensitization - Breakpoint0.10.10.2-0.20.1-0.30.3-0.3-0.4-0.5-0.0-0.3
Sum of active levers in priming session hrs 5-62.02.02.9-1.71.4-1.41.4-1.2-1.4-1.0-1.7-1.3
Progressive ratio0.50.62.61.6-0.20.2-0.40.40.60.70.70.9
Food seeking constrained by brief footshock0.20.31.41.20.0-0.0-0.10.10.30.30.20.9
Seeking ratio, punishment vs. effort0.10.21.1-1.0-0.10.10.1-0.1-0.1-0.3-0.4-0.2
Retroperitoneal fat weight2.89.311.6-1.93.4-3.43.2-3.1-3.0-2.7-3.0-3.4
Reaction time number correct0.50.71.3-0.3-1.11.1-0.90.90.80.60.81.0
Reaction time mean minus median3.44.55.6-1.12.1-2.12.2-2.3-2.3-2.4-2.2-2.2
Reaction time mean minus median AUC1.72.33.1-0.11.6-1.71.6-1.7-1.6-1.8-1.3-1.6
Reaction time num false alarms1.11.52.1-0.21.2-1.31.2-1.3-1.4-1.4-0.9-1.4
Reaction time num false alarms AUC1.72.43.2-0.91.5-1.61.5-1.7-1.7-1.8-1.2-1.8
Reaction time trials correct on left0.50.71.3-0.3-1.11.1-0.90.90.80.60.81.0
Reaction time trials on left0.50.71.2-0.2-1.01.1-0.90.80.80.60.70.9
Reaction time mean1.31.93.01.41.6-1.71.4-1.3-1.2-0.8-1.4-1.3
Reaction time mean AUC1.72.23.61.21.8-1.91.5-1.5-1.4-1.0-1.5-1.5
Median of all reaction times1.01.44.02.01.4-1.51.0-0.9-0.7-0.3-1.0-0.9
Reaction time omissions1.72.33.21.11.7-1.81.4-1.5-1.5-1.3-1.4-1.8
Reaction time false alarm rate2.43.34.5-0.81.9-2.01.8-1.9-2.0-1.9-1.5-2.1
Reaction time premature initiation rate0.10.10.2-0.20.3-0.20.3-0.3-0.3-0.4-0.4-0.1
Reaction time premature initiations0.00.00.1-0.3-0.10.2-0.00.10.1-0.2-0.10.3
Std. dev. reaction times2.23.03.80.01.9-2.01.8-1.9-1.8-1.7-1.8-1.7
Reaction time trials completed0.50.71.2-0.2-1.01.1-0.90.80.80.60.70.9
Reaction time trials AUC0.20.30.7-0.3-0.80.8-0.60.60.50.30.50.7
Run reversals in cocaine runway, females0.20.20.4-0.30.5-0.50.5-0.4-0.5-0.3-0.6-0.4
Run reversals in cocaine runway, males0.70.71.41.0-0.80.7-0.80.80.80.51.20.7
Latency to leave start box in cocaine runway0.20.20.50.7-0.30.2-0.40.50.30.7-0.2-0.0
Latency to leave start box in cocaine runway, F0.91.02.20.3-1.21.0-1.11.21.11.50.50.6
Latency to leave start box in cocaine runway, M1.00.91.30.21.0-1.11.0-1.0-1.0-1.2-0.9-1.1
Std. dev. time between licks in bursts0.30.30.6-0.20.3-0.50.5-0.5-0.7-0.8-0.5-0.8
Total sessions with >9 infusions0.10.10.2-0.20.2-0.20.2-0.2-0.3-0.2-0.5-0.4
Short access day 1 total inactive lever presses0.91.01.61.3-0.81.0-0.90.91.00.91.11.0
Short access day 10 total inactive lever presses1.11.22.0-0.0-1.41.4-1.21.11.11.01.11.1
Short access day 1 total infusions0.10.10.40.70.4-0.40.2-0.10.00.3-0.3-0.0
Short access day 10 total infusions0.60.71.0-0.11.0-1.00.9-0.9-0.8-0.7-1.0-0.8
Short access total infusions0.10.10.20.50.2-0.20.10.00.10.5-0.50.2
Short access day 1 locomotion0.40.50.9-0.01.0-0.90.8-0.8-0.6-0.7-0.1-0.6
Short access day 10 total locomotion0.80.91.20.91.1-1.00.9-1.0-0.9-0.9-0.6-1.0
Short access total locomotion1.21.32.00.21.4-1.31.3-1.2-1.1-1.0-0.9-1.1
One hour access (0.3 mA shock)0.80.93.10.5-1.00.8-0.90.80.90.51.80.8
Compulsive drug intake0.30.31.01.00.3-0.40.10.00.40.21.00.2
One hour access (shock baseline)0.20.21.0-1.0-0.40.3-0.2-0.0-0.1-0.40.4-0.1
Social response proportion1.51.62.7-1.4-1.61.6-1.31.11.10.91.10.9
Social responses0.30.43.2-1.8-0.40.4-0.1-0.1-0.1-0.40.1-0.4
Social time0.20.20.91.00.6-0.60.3-0.10.1-0.00.50.1
Soleus weight0.51.47.6-2.80.20.10.6-0.7-1.0-1.1-1.2-0.9
Bone: stiffness0.10.21.0-1.0-0.10.20.1-0.1-0.3-0.4-0.2-0.1
Tibialis anterior weight0.93.019.5-4.4-0.50.70.3-0.6-1.0-1.1-1.7-1.0
Time to tail flick, vehicle, before self-admin0.10.10.20.20.4-0.40.3-0.3-0.3-0.0-0.4-0.3
Time to tail flick, vehicle, after self-admin0.10.10.1-0.20.4-0.30.3-0.2-0.2-0.30.0-0.2
Time to tail flick, test, before self-admin0.50.50.9-0.0-0.90.8-0.80.70.60.80.30.5
Time to tail flick, test, after self-admin0.20.21.5-1.20.1-0.20.3-0.2-0.20.1-0.6-0.3
Delta time to tail flick, vehicle, before/after SA0.10.10.2-0.10.4-0.30.4-0.3-0.2-0.40.1-0.2
Delta time to tail flick, test, before/after SA0.90.81.1-0.71.0-1.01.0-0.9-0.9-0.8-1.0-0.8
Tibia length2.67.312.3-0.1-3.43.5-3.02.82.62.81.82.7
Ambulatory time before self-admin2.52.63.5-1.21.7-1.61.7-1.8-1.7-1.9-1.1-1.7
Ambulatory time after self-admin0.80.91.5-1.20.8-0.80.9-0.9-1.0-1.0-0.8-1.0
Bone: tissue strength0.60.60.80.5-0.80.7-0.80.80.80.90.80.5
Total heroin consumption4.45.17.4-1.02.7-2.62.6-2.4-2.2-2.5-1.7-2.1
Bone: trabecular number0.60.96.2-2.5-0.50.7-0.1-0.1-0.3-0.3-0.9-0.3
Bone: trabecular spacing0.50.63.51.90.9-1.00.6-0.4-0.2-0.20.2-0.1
Bone: trabecular thickness1.82.110.0-3.20.3-0.30.8-1.0-1.2-1.2-1.6-1.3
Bone: trabecular tissue density1.31.92.4-1.21.3-1.41.3-1.4-1.5-1.4-1.3-1.6
Water consumed over 24 hours2.63.14.61.0-2.12.1-2.01.81.71.51.71.7
Number of responses in last shaping day0.10.10.20.4-0.30.3-0.40.40.40.30.30.3