Hub : Genes

Elk3

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose gene expression Elk3 0.19 0.09 3.2e-11 0.04 0.08 0.06 0.07 9.5e-06 1.3e-09 1.1e-07 3.5e-08
2 NAcc gene expression Elk3 0.06 0.03 1.3e-05 0.04 0.04 0.06 0.06 5.9e-06 5.7e-06 3.1e-07 9.5e-08
3 OFC mRNA stability Elk3 0.38 0.13 3.4e-06 0.22 0.2 0.17 0.21 5.9e-06 1.9e-05 7.5e-05 1.1e-05
4 Brain gene expression Elk3 0.18 0.08 9.3e-06 0.06 0.05 0.04 0.03 2.5e-06 3.4e-05 6.9e-05 8.2e-04
5 PL gene expression Elk3 0.19 0.07 6.1e-08 0.07 0.08 0.08 0.07 1.1e-08 3.9e-09 2.4e-09 1.8e-08
6 PL mRNA stability Elk3 0.37 0.1 0.0e+00 0.24 0.24 0.26 0.26 2.3e-26 5.8e-26 5.7e-28 2.0e-28
7 Brain mRNA stability Elk3 0.39 0.11 3.3e-14 0.16 0.11 0.16 0 2.8e-14 1.1e-10 1.3e-14 3.4e-01
8 IL mRNA stability Elk3 0.34 0.14 1.2e-04 0.18 0.19 0.23 0.23 4.5e-05 3.1e-05 3.2e-06 2.3e-06
9 BLA mRNA stability Elk3 0.55 0.1 1.3e-08 0.11 0.09 0.1 0.11 1.9e-06 2.1e-05 6.2e-06 1.6e-06
10 NAcc mRNA stability Elk3 0.27 0.11 2.7e-11 0.1 0.08 0.11 0.1 3.7e-11 5.3e-10 1.5e-12 1.6e-11

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10
Bone: apparent density0.10.20.91.00.50.20.30.4-0.20.2-0.50.40.2
Area under the delay curve0.50.51.4-1.1-0.70.80.30.5-0.50.6-0.5-1.20.6
BMI with tail0.51.68.42.91.60.80.41.3-0.50.9-1.10.70.2
BMI without tail1.22.512.43.52.8-0.7-0.9-0.21.0-0.60.21.3-1.0
Body weight2.912.049.47.05.8-2.4-1.9-1.22.8-1.91.52.3-2.7
Weight adjusted by age0.60.73.01.71.5-0.4-0.00.10.4-0.10.50.8-0.6
Bone surface0.10.20.70.80.40.20.10.3-0.30.2-0.60.70.1
Bone volume0.30.52.31.50.70.30.30.6-0.40.4-0.80.70.1
Breakpoint value in progressive ratio session0.20.30.6-0.0-0.50.40.30.4-0.60.5-0.80.80.1
Number of licking bursts0.20.20.40.2-0.10.50.70.7-0.50.5-0.60.20.6
Context. condit. distance diff. score0.40.51.51.20.5-0.6-0.7-0.40.7-0.60.70.6-0.7
Locomotion velocity, session 10.30.31.8-1.3-0.90.1-0.1-0.2-0.10.00.0-0.3-0.0
Locomotion distance, session 10.50.60.8-0.8-0.80.80.70.7-0.80.9-0.7-0.90.8
Locomotion velocity, session 20.10.20.5-0.5-0.3-0.0-0.4-0.20.4-0.30.6-0.0-0.7
Locomotion distance, session 22.02.94.6-0.5-0.62.11.82.1-1.82.1-1.8-1.41.7
Locomotion velocity, session 30.80.95.01.10.9-0.0-0.20.20.3-0.10.52.2-1.4
Locomotion distance, session 30.30.31.51.20.90.30.10.50.10.30.10.3-0.3
Stereotopy head waving bouts, day 31.41.72.4-1.1-1.61.21.11.0-1.61.2-1.5-0.91.5
Stereotopy head waving duration, day 30.40.51.7-0.9-1.30.50.60.4-0.80.5-0.70.10.3
Locomotion velocity, session 70.20.20.70.50.1-0.0-0.2-0.20.5-0.20.60.3-0.9
Locomotion distance, session 70.10.20.6-0.20.10.1-0.2-0.10.5-0.10.70.3-0.7
Stereotopy head waving bouts, day 71.61.83.90.10.1-1.3-1.2-1.21.4-1.31.52.0-1.9
Stereotopy head waving duration, day 71.51.84.40.30.3-1.4-1.2-1.21.3-1.31.42.1-1.9
Locomotion velocity, session 80.10.10.30.00.6-0.0-0.30.10.4-0.00.50.3-0.4
Locomotion distance, session 80.81.22.21.51.01.20.91.5-0.81.3-1.1-0.50.9
Degree of sensitization distance0.40.41.3-1.1-0.4-0.5-0.5-0.60.5-0.50.70.4-0.5
Degree of sensitization stereotypy2.52.85.40.10.1-1.7-1.5-1.51.8-1.71.92.3-2.3
Conditioned locomotion0.40.41.81.00.1-0.5-0.6-0.80.2-0.5-0.3-1.40.3
Cocaine response after cond. corrected0.70.81.4-1.00.7-1.0-0.9-0.91.2-0.91.1-0.0-0.6
Cocaine response after cond. not corrected0.30.31.3-1.10.2-0.5-0.3-0.40.7-0.40.70.2-0.4
Cocaine response before conditioning0.81.01.7-0.1-1.21.11.31.1-1.21.2-1.10.30.6
Saline control response0.00.10.3-0.3-0.6-0.1-0.0-0.1-0.10.1-0.1-0.4-0.1
Bone: connectivity density0.50.71.0-0.21.0-0.9-1.0-0.80.9-1.00.90.9-0.6
Bone: cortical apparent density0.81.13.71.91.4-1.1-0.9-0.70.8-0.70.3-1.20.1
Bone: cortical area1.01.55.72.41.3-1.0-0.6-0.40.7-0.70.21.9-1.2
Bone: cortical porosity0.70.82.60.2-0.0-0.6-0.6-0.70.7-0.80.81.6-1.5
Bone: cortical porosity0.30.31.60.4-0.2-0.1-0.2-0.20.2-0.40.31.3-1.0
Bone: cortical thickness1.11.74.22.01.1-1.6-1.3-1.11.2-1.30.71.1-1.3
Bone: cortical thickness2.02.34.00.61.0-2.0-1.6-1.61.6-1.81.31.5-1.6
Bone: cortical tissue density0.81.13.51.91.4-1.1-0.9-0.70.8-0.70.4-1.20.1
Condit. Reinf. active minus inactive responses3.64.16.4-1.4-2.52.21.91.8-2.32.0-2.1-1.62.1
Condit. Reinf. active-inactive response ratio2.93.18.0-1.2-2.81.91.71.4-2.01.6-1.7-1.31.5
Condit. Reinf. active responses3.74.58.3-2.5-2.92.31.91.8-2.42.0-2.0-1.01.9
Condit. Reinf. inactive responses0.40.53.2-1.8-0.80.50.30.3-0.50.4-0.30.30.4
Incentive salience index mean4.85.89.0-1.4-2.33.02.62.6-2.82.7-2.5-1.12.2
Condit. Reinf. lever presses2.83.76.7-0.5-1.02.62.32.6-2.22.4-2.0-0.21.6
Condit. Reinf. active minus inactive responses0.10.10.91.0-0.2-0.3-0.0-0.1-0.1-0.1-0.40.4-0.3
Condit. Reinf. active-inactive response ratio0.10.10.40.3-0.40.00.40.3-0.20.1-0.20.7-0.5
Condit. Reinf. active responses0.30.41.31.1-0.40.40.60.6-0.70.5-0.9-0.00.3
Condit. Reinf. inactive responses0.30.31.30.60.10.10.0-0.1-0.40.1-0.7-1.20.9
Condit. Reinf. lever presses1.11.52.51.51.3-1.6-1.3-1.31.2-1.30.90.7-1.1
Condit. Reinf. lever reinforcers received0.20.31.41.2-0.30.30.40.4-0.60.4-0.8-0.00.2
Conditioned reinforcement - actives1.11.12.90.2-0.61.51.71.0-0.81.0-1.1-0.31.1
Conditioned reinforcement - inactives0.20.30.5-0.7-0.2-0.3-0.3-0.50.5-0.50.70.7-0.4
Conditioned locomotion0.10.10.40.40.00.10.6-0.10.5-0.10.30.4-0.1
Patch foraging indifference point 0 sec0.91.53.10.10.8-1.8-1.6-1.71.3-1.51.1-0.1-0.7
Patch foraging indifference point AUC0.91.03.50.41.9-1.1-1.5-0.71.1-0.90.60.5-0.4
Delay disc. indifference point, 0s delay0.60.71.6-1.0-0.50.80.60.4-0.50.7-0.8-1.31.2
Delay disc. indifference point, 16s delay1.11.12.6-0.4-1.01.61.11.6-1.01.3-1.0-0.10.5
Delay disc. indifference point, 2s delay0.10.10.6-0.7-0.40.30.10.0-0.10.3-0.0-0.80.1
Delay disc. indifference point, 24s delay0.50.51.30.2-0.11.10.81.1-0.50.9-0.70.00.2
Delay disc. indifference point, 4s delay0.50.51.5-1.2-0.3-0.5-0.7-0.80.6-0.60.6-1.2-0.1
Delay disc. indifference point, 8s delay0.10.10.9-0.50.1-0.1-0.30.1-0.10.1-0.1-1.00.3
Indifference point function ln k0.10.20.7-0.3-0.80.40.8-0.0-0.40.3-0.1-0.30.1
Indifference point function log k0.10.20.7-0.3-0.80.40.8-0.0-0.40.3-0.1-0.30.1
Patch foraging total patch changes 0 sec1.11.73.70.31.0-1.9-1.8-1.71.4-1.61.1-0.2-0.7
Patch foraging total patch changes 12 sec1.92.44.41.32.0-2.1-1.9-1.51.6-1.61.20.4-1.1
Patch foraging total patch changes 18 sec1.01.22.90.10.8-1.6-1.7-1.41.2-1.20.8-0.7-0.3
Patch foraging total patch changes 24 sec1.41.73.20.51.5-1.8-1.8-1.51.5-1.41.10.2-0.9
Patch foraging total patch changes 6 sec0.30.41.1-0.10.5-1.0-1.0-0.80.5-0.70.20.1-0.1
Patch foraging time to switch 0 sec0.10.21.00.6-1.00.20.40.2-0.40.1-0.2-0.30.1
Patch foraging water rate 0 sec0.91.42.20.80.61.21.01.4-1.21.5-1.5-1.11.3
Patch foraging water rate 12 sec0.10.20.50.50.60.20.60.40.10.30.30.7-0.6
Patch foraging water rate 18 sec1.31.83.8-0.0-0.91.72.01.7-1.51.7-1.20.40.8
Patch foraging water rate 24 sec0.81.12.91.71.30.71.11.0-0.71.2-1.0-0.80.9
Patch foraging water rate 6 sec1.42.07.12.71.91.11.21.5-0.81.4-1.1-0.40.7
Seeking ratio, delayed vs. immediate footshock0.10.10.7-0.80.60.0-0.1-0.10.0-0.1-0.1-0.40.4
Distance traveled before self-admin0.10.10.50.50.7-0.1-0.20.5-0.10.2-0.00.4-0.1
Distance traveled after self-admin0.50.51.90.0-0.10.70.81.4-0.81.1-0.40.6-0.1
Extensor digitorum longus weight0.31.23.01.70.11.00.91.2-1.30.8-1.60.80.4
Bone: elastic displacement0.30.41.9-1.4-0.6-0.4-0.5-0.70.2-0.50.2-0.50.2
Bone: elastic work0.30.40.8-0.9-0.4-0.7-0.4-0.80.4-0.80.50.7-0.6
Bone: endosteal estimation1.02.34.20.1-0.91.91.82.0-1.71.8-1.70.71.2
Bone: endosteal perimeter0.30.71.91.41.00.50.61.0-0.60.8-1.00.20.7
Epididymis fat weight0.82.05.72.41.6-0.9-1.0-0.51.3-0.81.31.5-1.8
Delta time in closed arm before/after self-admin0.20.21.2-0.2-0.30.10.30.10.3-0.20.61.1-0.7
Delta time in open arm before/after self-admin0.50.51.4-0.20.5-0.9-1.2-0.80.6-0.70.5-0.4-0.3
Diff in mean of infusions in LGA sessions0.60.73.2-1.6-1.80.20.5-0.2-0.60.2-0.40.40.0
Delay discount exponential model param0.30.41.30.90.5-0.6-0.2-0.40.3-0.40.31.2-0.4
Extinction: sum of active levers before priming0.90.93.4-1.8-1.41.01.00.7-0.70.7-0.50.30.5
Active lever presses in extinction session 60.70.71.6-0.0-0.50.90.91.3-1.11.1-0.90.50.2
Bone: final force0.60.94.91.60.4-0.20.30.20.1-0.2-0.02.2-1.1
Bone: final moment0.50.95.11.40.2-0.00.40.3-0.0-0.0-0.12.3-1.1
Food consumed during 24 hour testing period0.50.61.0-0.60.4-0.8-0.9-0.91.0-0.81.00.2-0.8
Glucose0.10.20.70.20.10.10.60.3-0.20.4-0.3-0.80.6
Heart weight0.40.53.60.50.4-0.2-0.10.20.3-0.20.41.9-1.1
Delay discount hyperbolic model param0.20.21.20.90.3-0.30.0-0.10.1-0.20.11.1-0.2
Intermittent access intake day 1-15 change0.70.71.50.1-1.21.10.40.8-1.00.7-1.0-0.60.6
Intermittent access intake escalation0.30.31.4-0.2-1.20.7-0.10.2-0.50.2-0.5-0.30.2
Intermittent access intake escalation 20.60.62.3-0.4-1.50.90.20.3-0.80.5-0.8-0.80.7
Intermitt. access day 1 inactive lever presses1.81.911.1-3.3-1.5-0.8-0.8-1.30.7-0.91.00.3-0.4
Intermitt. access day 15 inactive lever presses2.02.24.7-1.7-0.5-1.0-1.3-1.51.2-1.41.72.2-1.8
Intermitt. access escalation Index0.90.81.6-0.2-0.3-0.9-1.0-1.31.0-1.21.10.1-0.9
Intermittent access day 1 total infusions0.70.81.9-0.9-0.91.01.40.9-0.70.9-0.2-0.80.6
Intermittent access day 15 total infusions1.41.53.1-0.7-1.51.81.61.4-1.21.4-0.7-0.70.7
Intermittent access terminal intake (last 3 days)2.02.24.2-0.5-1.52.01.91.7-1.51.7-1.1-0.91.1
Intermittent access total infusions2.83.15.8-1.2-1.62.42.42.0-1.72.0-1.1-1.21.4
Intermittent access day 1 locomotion0.30.31.0-0.70.3-0.40.2-0.30.7-0.31.0-0.2-0.3
Intermittent access day 15 total locomotion0.00.00.1-0.2-0.00.10.20.00.00.10.2-0.20.0
Intermittent access total locomotion0.20.20.5-0.7-0.60.40.70.4-0.20.30.1-0.40.2
Intermittent access standard deviation2.83.04.9-1.0-1.72.21.82.1-1.82.1-1.3-1.51.6
Left kidney weight1.74.813.43.73.2-1.7-1.4-0.91.8-1.41.22.8-2.1
Right kidney weight1.74.810.63.33.0-1.8-1.4-1.11.9-1.51.33.0-2.3
Cocaine induced anxiety1.61.83.7-0.10.8-1.5-1.2-1.51.8-1.51.90.8-1.3
Post-drug Anxiety0.20.30.8-0.1-0.1-0.4-0.6-0.30.6-0.40.90.4-0.7
Baseline Anxiety0.20.30.70.3-0.50.30.10.6-0.80.6-0.80.10.2
Tail length4.212.829.65.45.1-3.7-3.0-2.73.7-3.12.71.9-3.0
Length with tail5.018.342.46.56.3-4.3-3.3-3.04.5-3.53.42.2-3.8
Length without tail1.94.311.63.43.1-1.9-1.5-1.22.0-1.41.61.1-2.1
Times rat made contact with spout2.12.43.6-0.7-1.51.91.91.7-1.71.8-1.7-0.61.2
Lifetime Intake2.62.96.1-0.5-1.42.32.52.0-1.62.0-1.2-1.21.3
Liver weight, left0.50.91.70.60.9-0.6-1.0-0.61.1-0.71.01.3-1.1
Liver weight, right0.61.06.82.61.50.3-0.00.70.00.2-0.10.8-0.4
Locomotor activity1.42.310.33.22.1-0.8-0.9-0.40.8-0.50.21.9-1.4
Locomotor testing distance0.40.73.11.80.6-0.1-0.20.00.10.1-0.31.6-0.8
Locomotor testing rearing0.20.20.60.80.3-0.7-0.4-0.60.3-0.4-0.00.6-0.3
Locomotion in novel chamber0.60.81.6-0.5-0.71.31.01.0-1.01.1-0.8-0.50.5
Locomotion in novel chamber post-restriction0.10.20.8-0.90.20.40.30.4-0.00.20.40.30.0
Fecal boli incidents, locomotor time 10.50.53.01.01.7-0.5-0.4-0.10.6-0.2-0.0-0.60.5
Change in fecal boli incidents, locomotor task0.60.62.6-1.2-1.60.60.60.2-0.50.4-0.20.5-0.1
Time >=10cm from walls, locomotor time 10.70.81.60.40.1-1.1-0.9-1.31.1-1.10.90.3-0.8
Bouts of movement, locomotor time 10.30.30.90.50.00.40.90.2-0.10.3-0.4-0.90.9
Total resting periods, locomotor time 10.20.21.00.4-0.20.41.00.1-0.10.2-0.2-0.60.6
Rest time, locomotor task time 10.20.20.6-0.10.1-0.3-0.1-0.60.7-0.70.50.8-0.4
Distance moved, locomotor task time 10.90.91.4-0.2-1.11.00.90.8-1.21.0-1.2-1.00.9
Vertical activity count, locomotor time 11.01.01.91.2-0.40.90.71.0-1.31.1-1.4-1.10.7
Time >=10cm from walls, locomotor time 20.20.20.8-0.8-0.90.10.00.1-0.30.3-0.1-0.30.1
Bouts of movement, locomotor time 20.10.20.70.80.3-0.4-0.0-0.30.2-0.3-0.1-0.70.0
Total resting periods, locomotor time 20.20.20.90.90.1-0.10.3-0.0-0.1-0.0-0.4-0.90.3
Rest time, locomotor task time 20.40.41.10.7-0.60.91.00.5-0.40.4-0.80.30.5
Distance moved, locomotor task time 20.10.10.3-0.50.2-0.4-0.4-0.30.2-0.20.50.0-0.3
Vertical activity count, locomotor time 20.30.41.31.20.8-0.20.00.4-0.50.6-0.6-0.80.2
Light reinforcement 11.32.36.91.71.7-0.9-0.8-0.51.2-0.81.52.6-1.9
Light reinforcement 20.40.62.3-0.50.2-0.5-0.6-0.50.6-0.60.91.5-0.8
Bone: marrow area1.02.24.10.1-0.81.91.72.0-1.71.8-1.60.61.2
Bone: maximum diameter0.40.73.51.91.2-0.00.20.5-0.10.3-0.61.0-0.0
Bone: maximum force0.50.95.51.40.3-0.30.10.10.1-0.2-0.02.4-1.0
Bone: maximum moment0.50.95.91.20.0-0.10.30.3-0.1-0.1-0.22.4-1.0
Mean time between licks in bursts1.21.72.81.30.21.11.01.3-1.31.3-1.7-1.51.6
Mean num. licks in bursts0.91.12.6-1.4-1.61.20.90.8-1.11.0-0.7-0.70.5
Cd content in liver2.12.33.61.90.81.21.61.8-1.31.6-1.7-1.21.7
Co content in liver0.50.62.10.71.4-0.6-0.8-0.50.5-0.40.3-1.50.3
Cu content in liver0.60.71.50.81.2-0.9-1.1-0.90.9-0.80.6-0.2-0.4
Fe content in liver0.20.20.50.6-0.30.60.70.5-0.50.4-0.30.4-0.2
K content in liver0.40.40.8-0.30.2-0.7-0.9-0.90.5-0.80.4-0.2-0.4
Mg content in liver0.10.20.3-0.2-0.4-0.4-0.5-0.60.2-0.40.30.1-0.4
Mn content in liver0.20.21.00.3-1.00.50.50.3-0.50.3-0.5-0.1-0.0
Na content in liver2.22.34.00.20.3-1.7-1.9-2.01.6-1.91.70.6-1.8
Rb content in liver0.40.51.1-0.90.5-0.6-1.1-0.90.7-0.90.8-0.1-0.2
Se content in liver0.10.10.5-0.0-0.40.40.30.2-0.00.20.10.7-0.6
Sr content in liver1.00.94.0-0.40.7-0.2-0.2-0.20.7-0.61.22.0-1.4
Zn content in liver0.10.10.20.40.50.20.00.30.00.20.3-0.2-0.2
Bone: minimum diameter0.91.710.93.31.20.10.30.8-0.10.4-0.51.6-0.7
Time in familiar zone, hab. session 10.20.20.70.30.8-0.5-0.5-0.20.5-0.30.10.1-0.0
Time in novel zone, hab. session 10.30.31.9-0.5-1.40.40.40.1-0.50.2-0.1-0.50.2
Total zone transitions, hab. session 12.73.86.81.7-0.11.92.02.2-2.22.3-2.6-1.31.9
Total locomotion distance, hab. session 13.85.49.51.4-0.72.52.52.7-2.72.9-3.1-1.32.3
Locomotion velocity, hab. session 15.17.312.51.4-0.63.03.03.2-3.23.4-3.5-1.12.5
Time in familiar zone, hab. session 20.20.21.00.40.3-0.0-0.30.20.1-0.10.11.0-0.5
Time in novel zone, hab. session 20.20.21.0-0.5-0.1-0.20.1-0.40.0-0.1-0.1-1.00.5
Total zone transitions, hab. session 22.02.54.20.6-0.51.91.92.1-1.92.0-1.9-0.51.3
Total locomotion distance, hab. session 25.26.911.70.4-1.32.82.82.8-3.13.1-3.4-2.03.0
Locomotion velocity, hab. session 25.57.411.90.4-1.22.93.02.9-3.23.2-3.5-2.13.1
Novel to familiar place preference ratio1.71.73.5-0.71.4-1.7-1.4-1.91.6-1.41.3-0.4-0.4
Novelty place preference1.92.04.0-0.81.3-1.8-1.5-2.01.7-1.61.5-0.2-0.7
Time in novel zone, NPP test2.32.34.7-0.61.4-2.0-1.7-2.21.9-1.71.6-0.0-0.9
Total zone transitions, NPP test0.20.31.21.10.5-0.10.00.1-0.10.2-0.6-0.60.5
Total locomotion distance, NPP test2.02.75.10.3-1.01.61.71.6-1.81.9-2.3-1.41.9
Locomotion velocity, NPP test2.33.25.6-0.0-1.31.81.91.7-2.02.1-2.4-1.52.1
Intraocular pressure0.81.17.9-2.8-1.20.30.30.0-0.10.30.2-0.91.0
Delta distance traveled before/after self-admin0.30.30.90.0-0.80.70.90.6-0.50.5-0.20.4-0.3
Delta ambulatory time before/after self-admin0.40.51.3-0.5-1.10.71.00.6-0.70.7-0.40.10.0
Parametrial fat weight0.40.91.31.11.1-0.9-0.8-0.90.8-1.00.60.9-1.0
Pavlov. Cond. lever latency1.41.83.11.11.4-1.8-1.5-1.51.5-1.51.3-0.2-0.9
Pavlov. Cond. magazine entry latency2.12.74.10.2-1.42.01.91.9-2.01.8-1.9-0.61.4
Pavlov. Cond. change in total contacts4.04.36.4-1.1-2.52.52.52.1-2.42.2-2.0-1.11.6
Pavlov. Cond. index score2.43.05.0-0.7-1.72.22.12.1-2.02.1-1.7-0.31.2
Pavlov. Cond. latency score2.63.35.4-0.9-1.82.32.22.2-2.12.2-1.8-0.11.2
Pavlov. Cond. lever contacts1.41.62.9-0.7-1.01.71.61.6-1.41.6-1.10.20.7
Pavlov. Cond. magazine entry number2.02.53.7-0.21.5-1.9-1.8-1.81.9-1.81.71.0-1.4
Pavlov. Cond. intertrial magazine entries0.10.10.4-0.4-0.0-0.2-0.2-0.30.0-0.0-0.1-0.60.3
Pavlov. Cond. lever-magazine prob. diff.2.43.04.8-0.5-1.52.22.12.1-2.02.0-1.8-0.51.4
Pavlov. Cond. response bias2.42.94.9-0.4-1.62.22.02.0-2.02.0-1.8-0.71.4
Pavlov. Cond. lever latency0.20.30.6-0.30.30.60.60.7-0.50.5-0.30.80.3
Pavlov. Cond. magazine entry latency0.40.52.70.4-0.30.20.10.4-0.40.5-0.7-1.70.9
Pavlov. Cond. change in total contacts0.91.27.20.60.10.40.40.4-0.60.8-1.1-2.71.3
Pavlov. Cond. index score0.60.86.10.5-0.1-0.2-0.2-0.2-0.00.2-0.5-2.50.9
Pavlov. Cond. latency score0.60.86.20.3-0.3-0.1-0.2-0.2-0.10.2-0.5-2.51.0
Pavlov. Cond. lever contacts0.20.20.60.7-0.1-0.6-0.5-0.60.5-0.40.2-0.8-0.3
Pavlov. Cond. magazine entry number1.21.57.1-0.70.0-0.6-0.5-0.70.8-1.01.32.7-1.8
Pavlov. Cond. intertrial magazine entries2.73.55.02.01.6-2.0-1.6-1.71.8-1.91.62.2-2.1
Pavlov. Cond. lever-magazine prob. diff.0.60.75.80.5-0.0-0.3-0.3-0.30.00.1-0.4-2.40.9
Pavlov. Cond. response bias0.20.31.91.00.3-0.3-0.3-0.20.2-0.0-0.2-1.40.4
Time in closed arm before self-admin0.30.32.41.50.40.1-0.10.1-0.10.0-0.50.2-0.2
Time in closed arm after self-admin0.50.52.71.10.40.20.40.20.4-0.20.41.6-0.8
Time in open arm before self-admin0.80.92.1-1.4-1.30.81.30.5-0.80.8-0.6-0.40.7
Time in open arm after self-admin0.30.40.8-0.9-0.3-0.7-0.8-0.80.4-0.50.2-0.80.0
Bone: periosteal estimation0.40.92.41.50.30.60.71.1-0.60.7-0.91.5-0.0
Bone: periosteal perimeter0.30.52.51.60.9-0.20.10.4-0.10.2-0.60.8-0.0
Bone: post-yield work0.50.75.0-0.1-0.3-0.3-0.30.00.4-0.30.62.2-1.2
Progressive ratio test 1 active lever presses0.70.71.5-0.5-0.81.21.21.1-0.71.0-0.2-0.70.3
Progressive ratio test 1 breakpoint1.21.22.5-0.3-0.81.61.61.6-1.11.4-0.5-0.50.5
Progressive ratio test 1 inactive lever presses0.40.40.8-0.9-0.3-0.5-0.3-0.80.4-0.70.80.8-0.6
Progressive ratio test 2 active lever presses2.42.65.5-0.7-1.52.32.22.0-1.61.8-1.2-0.61.0
Progressive ratio test 2 breakpoint2.22.55.1-0.6-1.52.32.21.9-1.61.8-1.1-0.71.0
Progressive ratio test 2 inactive lever presses1.61.84.4-1.8-2.11.71.61.4-1.01.2-0.40.70.2
Incentive Sensitization - Responses0.80.82.0-0.5-1.11.41.21.1-0.81.0-0.60.40.2
Incentive Sensitization - Breakpoint0.50.51.4-0.5-0.91.20.90.8-0.60.7-0.40.40.1
Sum of active levers in priming session hrs 5-60.80.81.80.3-0.41.01.11.3-0.91.2-0.9-0.10.6
Progressive ratio0.20.21.1-0.9-1.00.10.5-0.0-0.00.10.10.20.1
Food seeking constrained by brief footshock0.20.31.1-0.5-0.60.51.00.1-0.20.30.0-0.80.1
Seeking ratio, punishment vs. effort0.10.10.8-0.10.10.40.30.3-0.30.3-0.3-0.90.2
Retroperitoneal fat weight0.41.28.42.91.8-0.4-0.2-0.10.3-0.0-0.2-0.2-0.1
Reaction time number correct0.00.00.10.20.30.00.0-0.20.1-0.10.0-0.00.0
Reaction time mean minus median0.10.10.3-0.3-0.2-0.5-0.5-0.40.1-0.3-0.20.20.1
Reaction time mean minus median AUC0.30.41.0-1.0-1.00.30.30.5-0.60.6-0.7-0.10.6
Reaction time num false alarms0.81.11.9-1.4-0.6-1.0-0.9-1.20.8-1.11.21.1-1.0
Reaction time num false alarms AUC1.01.42.4-1.5-0.7-1.1-1.0-1.30.9-1.21.21.3-1.1
Reaction time trials correct on left0.00.00.10.20.30.00.0-0.20.1-0.10.0-0.00.0
Reaction time trials on left0.00.00.10.20.3-0.0-0.0-0.20.2-0.10.10.1-0.0
Reaction time mean0.60.81.70.1-0.60.60.70.8-1.00.9-1.3-1.11.3
Reaction time mean AUC0.40.61.40.1-0.50.40.30.5-0.80.6-1.1-1.11.2
Median of all reaction times1.01.42.40.3-0.71.11.01.2-1.31.3-1.5-1.51.6
Reaction time omissions0.30.41.2-1.0-1.0-0.1-0.0-0.3-0.1-0.30.21.1-0.2
Reaction time false alarm rate0.50.62.5-1.6-1.1-0.5-0.5-0.70.3-0.60.60.8-0.6
Reaction time premature initiation rate1.31.83.51.9-0.01.41.81.5-1.51.4-1.50.60.7
Reaction time premature initiations0.71.03.51.90.40.91.30.9-0.90.9-1.00.70.3
Std. dev. reaction times0.00.10.2-0.1-0.4-0.2-0.2-0.1-0.1-0.1-0.40.30.2
Reaction time trials completed0.00.00.10.20.3-0.0-0.0-0.20.2-0.10.10.1-0.0
Reaction time trials AUC0.00.10.10.30.20.30.30.1-0.10.2-0.2-0.20.2
Run reversals in cocaine runway, females2.42.34.71.50.41.81.52.2-1.61.7-1.7-0.61.5
Run reversals in cocaine runway, males1.61.53.0-1.6-0.9-0.9-0.9-1.41.2-1.21.70.6-1.5
Latency to leave start box in cocaine runway0.20.21.01.00.8-0.5-0.5-0.10.3-0.10.1-0.4-0.2
Latency to leave start box in cocaine runway, F0.10.21.0-0.30.0-0.3-0.4-0.20.2-0.10.1-1.00.3
Latency to leave start box in cocaine runway, M1.91.85.52.32.1-1.1-1.0-0.50.9-0.90.81.4-1.3
Std. dev. time between licks in bursts0.10.20.50.7-0.30.30.20.3-0.40.3-0.4-0.70.3
Total sessions with >9 infusions2.02.15.2-0.5-0.82.02.31.8-1.31.7-0.9-1.21.2
Short access day 1 total inactive lever presses0.91.04.9-2.2-1.50.40.70.2-0.10.10.51.4-0.3
Short access day 10 total inactive lever presses1.51.73.1-0.90.0-1.6-1.8-1.61.2-1.51.21.1-1.3
Short access day 1 total infusions2.82.96.30.3-1.22.32.52.3-1.92.0-1.4-0.51.3
Short access day 10 total infusions0.30.41.0-0.1-0.20.81.00.7-0.40.7-0.2-0.80.4
Short access total infusions2.62.96.00.5-0.72.32.52.2-1.72.0-1.4-1.11.4
Short access day 1 locomotion0.40.41.50.0-0.30.91.20.9-0.70.8-0.30.30.2
Short access day 10 total locomotion0.91.01.6-1.1-1.30.91.10.9-0.91.0-0.7-1.01.1
Short access total locomotion0.70.71.8-0.8-0.41.01.31.0-0.71.0-0.4-0.60.9
One hour access (0.3 mA shock)4.45.28.6-0.4-2.02.92.72.7-2.42.7-2.2-1.61.9
Compulsive drug intake0.10.10.50.6-0.3-0.3-0.3-0.1-0.10.0-0.3-0.7-0.1
One hour access (shock baseline)1.11.33.1-0.7-1.11.81.61.4-1.11.3-0.70.00.6
Social response proportion1.41.54.62.20.91.21.11.6-0.91.3-1.0-0.20.7
Social responses1.11.55.32.30.41.01.21.4-1.11.3-1.3-0.00.6
Social time0.81.01.90.3-0.91.21.11.4-1.31.2-1.20.40.5
Soleus weight0.30.82.51.61.40.20.20.7-0.10.1-0.21.6-0.5
Bone: stiffness0.71.18.02.80.40.10.50.6-0.40.2-0.71.2-0.4
Tibialis anterior weight0.51.83.50.9-1.11.41.51.5-1.91.1-1.90.00.9
Time to tail flick, vehicle, before self-admin0.40.51.81.31.2-0.3-0.3-0.00.3-0.10.1-0.90.3
Time to tail flick, vehicle, after self-admin1.51.62.0-1.2-1.21.31.41.4-1.31.3-1.1-1.11.4
Time to tail flick, test, before self-admin0.40.40.60.70.6-0.4-0.4-0.50.8-0.50.60.7-0.7
Time to tail flick, test, after self-admin0.10.21.01.00.20.20.40.2-0.20.0-0.10.3-0.0
Delta time to tail flick, vehicle, before/after SA1.81.84.8-2.2-1.71.31.31.2-1.21.2-0.8-0.71.0
Delta time to tail flick, test, before/after SA0.10.10.20.2-0.40.10.30.2-0.40.2-0.3-0.40.2
Tibia length1.23.423.04.83.1-0.3-0.20.50.60.2-0.00.2-0.6
Ambulatory time before self-admin0.10.10.30.30.40.1-0.10.4-0.20.10.10.6-0.2
Ambulatory time after self-admin0.30.31.20.30.30.40.61.1-0.50.8-0.20.5-0.3
Bone: tissue strength0.30.21.21.10.2-0.4-0.4-0.40.3-0.4-0.10.6-0.3
Total heroin consumption0.91.02.80.30.6-1.1-0.9-0.90.9-0.90.81.7-1.4
Bone: trabecular number0.10.10.60.20.4-0.1-0.1-0.10.1-0.20.10.8-0.0
Bone: trabecular spacing0.20.20.5-0.7-0.1-0.5-0.5-0.60.5-0.40.3-0.2-0.3
Bone: trabecular thickness0.70.83.21.81.5-0.5-0.5-0.10.5-0.40.30.9-0.6
Bone: trabecular tissue density0.71.03.6-0.0-1.00.80.80.6-0.90.9-0.8-1.91.1
Water consumed over 24 hours0.10.10.3-0.60.30.20.10.20.10.20.1-0.20.2
Number of responses in last shaping day0.70.83.4-1.3-1.81.00.70.7-0.30.50.30.4-0.4