Hub : Genes

Plxnb1

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 BLA gene expression Plxnb1 0.09 0.06 1.2e-04 0.08 0.05 0.11 0.1 6.3e-05 8.6e-04 2.4e-06 7.0e-06
2 pVTA gene expression Plxnb1 0.21 0.12 3.3e-08 0.15 0.14 0.12 0.13 5.9e-07 1.3e-06 5.4e-06 4.4e-06
3 NAcc gene expression Plxnb1 0.08 0.05 2.4e-09 0.08 0.08 0.08 0.08 3.0e-09 1.8e-09 3.8e-09 3.1e-09
4 Liver gene expression Plxnb1 0.11 0.06 1.7e-16 0.11 0.12 0.11 0.11 8.9e-12 7.3e-13 1.7e-12 2.7e-12
5 Brain gene expression Plxnb1 0.27 0.14 0.0e+00 0.23 0.21 0.22 0.23 1.4e-21 1.3e-19 1.9e-20 8.9e-21
6 LHb gene expression Plxnb1 0.25 0.14 1.8e-03 0.08 0.01 0.03 0.04 7.0e-03 1.5e-01 7.6e-02 4.9e-02
7 Adipose gene expression Plxnb1 0.49 0.15 0.0e+00 0.13 0.22 0.23 0.22 2.3e-14 5.1e-24 2.3e-25 4.0e-24
8 Adipose alternative TSS XM_039081607.1 0.09 0.06 6.7e-03 0 0 0.01 -0 3.2e-01 1.1e-01 1.0e-02 4.3e-01
9 Adipose isoform ratio XM_039081607.1 0.13 0.08 3.2e-04 0.01 0.01 0.03 0.01 3.2e-02 7.1e-03 1.9e-04 1.7e-02

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9
Bone: apparent density0.30.41.4-0.00.2-0.30.6-0.00.0-0.9-1.2-1.1
Area under the delay curve1.51.62.5-1.5-1.41.2-0.9-1.3-1.2-1.6-1.1-1.1
BMI with tail0.41.22.41.11.6-0.80.70.90.8-1.3-1.1-1.2
BMI without tail1.12.44.42.02.1-1.71.61.61.8-0.1-0.9-0.9
Body weight3.816.029.25.25.4-4.64.14.84.52.40.50.5
Weight adjusted by age0.70.81.80.80.4-0.50.20.80.41.31.31.3
Bone surface0.10.31.0-0.4-0.20.3-0.2-0.4-0.5-1.0-0.5-0.5
Bone volume0.20.31.1-0.20.00.10.0-0.3-0.3-1.0-0.8-0.8
Breakpoint value in progressive ratio session0.20.20.60.80.3-0.40.50.50.6-0.0-0.3-0.3
Number of licking bursts0.80.92.6-0.4-0.60.7-1.0-0.4-0.40.91.61.5
Context. condit. distance diff. score0.00.00.10.1-0.00.0-0.10.10.10.00.20.2
Locomotion velocity, session 10.20.20.5-0.3-0.20.2-0.0-0.1-0.3-0.7-0.7-0.7
Locomotion distance, session 11.11.42.41.01.2-1.11.21.00.8-0.9-1.6-1.6
Locomotion velocity, session 20.40.41.0-0.5-0.40.6-0.6-0.5-0.7-1.0-0.6-0.7
Locomotion distance, session 20.91.23.7-0.30.00.10.2-0.1-0.4-1.8-1.9-1.9
Locomotion velocity, session 31.01.13.1-0.10.5-0.30.60.4-0.0-1.8-1.8-1.7
Locomotion distance, session 32.02.26.2-1.4-1.01.1-0.8-1.1-1.4-2.5-1.7-1.8
Stereotopy head waving bouts, day 30.80.93.00.40.10.1-0.50.10.31.31.71.7
Stereotopy head waving duration, day 30.70.82.40.60.4-0.40.20.50.71.61.41.4
Locomotion velocity, session 70.30.31.00.00.2-0.40.70.30.1-0.7-1.0-0.9
Locomotion distance, session 71.11.42.7-1.4-1.11.0-0.7-1.0-1.3-1.6-1.1-1.1
Stereotopy head waving bouts, day 70.10.10.2-0.1-0.10.00.1-0.20.0-0.3-0.5-0.4
Stereotopy head waving duration, day 70.30.30.50.70.7-0.70.70.60.70.1-0.5-0.4
Locomotion velocity, session 80.91.13.00.40.6-0.50.70.40.2-1.6-1.7-1.7
Locomotion distance, session 81.42.16.20.40.7-0.61.00.50.3-2.1-2.5-2.5
Degree of sensitization distance1.21.22.61.20.9-1.11.01.11.21.60.80.9
Degree of sensitization stereotypy0.30.30.90.10.3-0.40.60.30.3-0.4-0.9-0.8
Conditioned locomotion2.02.33.9-1.9-2.01.7-1.4-1.9-1.6-1.3-0.7-0.7
Cocaine response after cond. corrected0.91.12.70.90.4-0.3-0.10.50.71.61.71.6
Cocaine response after cond. not corrected1.82.03.01.71.4-1.20.81.41.51.71.41.4
Cocaine response before conditioning0.91.12.00.91.4-1.31.41.20.9-0.4-0.9-0.8
Saline control response1.41.83.81.31.3-1.71.91.51.50.4-0.9-0.8
Bone: connectivity density0.40.61.6-0.7-0.50.20.2-0.4-0.5-1.0-1.3-1.2
Bone: cortical apparent density0.10.20.4-0.6-0.50.4-0.3-0.5-0.4-0.3-0.3-0.2
Bone: cortical area0.50.82.0-0.4-0.50.8-1.2-0.6-0.60.61.41.2
Bone: cortical porosity0.20.20.7-0.3-0.3-0.10.5-0.1-0.1-0.2-0.8-0.7
Bone: cortical porosity0.20.30.8-0.5-0.60.10.3-0.3-0.3-0.4-0.9-0.8
Bone: cortical thickness0.61.13.80.50.30.1-0.60.20.21.31.91.8
Bone: cortical thickness0.00.10.2-0.0-0.00.1-0.2-0.10.00.20.40.5
Bone: cortical tissue density0.10.20.4-0.6-0.50.4-0.2-0.5-0.4-0.4-0.3-0.3
Condit. Reinf. active minus inactive responses0.30.31.10.00.2-0.1-0.10.40.01.10.90.9
Condit. Reinf. active-inactive response ratio0.80.82.40.30.3-0.3-0.00.70.31.61.51.4
Condit. Reinf. active responses0.10.10.3-0.0-0.20.2-0.4-0.2-0.10.50.50.5
Condit. Reinf. inactive responses0.50.61.3-0.5-0.70.7-0.6-1.0-0.5-1.1-0.7-0.7
Incentive salience index mean0.10.10.2-0.3-0.30.3-0.4-0.2-0.30.10.30.2
Condit. Reinf. lever presses1.01.41.9-1.3-1.31.4-1.3-1.4-1.3-1.2-0.3-0.4
Condit. Reinf. active minus inactive responses1.11.42.61.51.6-1.41.31.51.20.4-0.1-0.2
Condit. Reinf. active-inactive response ratio0.90.91.81.31.3-1.10.91.31.00.50.20.1
Condit. Reinf. active responses1.11.52.61.51.6-1.51.41.61.30.6-0.1-0.1
Condit. Reinf. inactive responses0.00.00.1-0.2-0.0-0.00.0-0.0-0.1-0.2-0.2-0.3
Condit. Reinf. lever presses1.31.83.61.61.9-1.61.41.71.30.4-0.3-0.3
Condit. Reinf. lever reinforcers received1.21.72.91.61.7-1.61.41.71.40.7-0.0-0.1
Conditioned reinforcement - actives0.20.20.8-0.5-0.90.5-0.4-0.4-0.3-0.5-0.4-0.4
Conditioned reinforcement - inactives1.82.14.2-1.1-1.21.4-1.7-1.1-1.00.62.02.1
Conditioned locomotion0.50.61.4-0.6-0.70.4-0.1-0.4-0.3-1.0-1.2-1.1
Patch foraging indifference point 0 sec1.11.83.51.41.5-1.71.91.61.41.0-0.10.1
Patch foraging indifference point AUC0.40.51.50.30.3-0.40.70.30.4-0.6-1.2-1.1
Delay disc. indifference point, 0s delay0.00.00.1-0.1-0.10.10.0-0.10.2-0.3-0.3-0.3
Delay disc. indifference point, 16s delay0.80.81.1-1.1-1.00.8-0.6-1.0-0.8-1.0-0.8-0.8
Delay disc. indifference point, 2s delay0.20.20.3-0.5-0.50.4-0.3-0.4-0.5-0.6-0.3-0.3
Delay disc. indifference point, 24s delay0.80.81.1-1.1-0.90.8-0.6-0.9-1.0-1.0-0.8-0.9
Delay disc. indifference point, 4s delay1.11.21.9-1.3-1.41.3-1.1-1.2-1.1-1.1-0.3-0.3
Delay disc. indifference point, 8s delay1.71.82.7-1.6-1.41.3-1.0-1.3-1.4-1.6-1.0-1.1
Indifference point function ln k0.81.12.8-1.0-0.50.7-0.6-0.9-1.0-1.7-1.1-1.3
Indifference point function log k0.81.12.8-1.0-0.50.7-0.6-0.9-1.0-1.7-1.1-1.3
Patch foraging total patch changes 0 sec1.32.03.31.61.6-1.71.81.71.51.30.20.5
Patch foraging total patch changes 12 sec1.01.31.81.21.2-1.31.31.31.21.30.50.7
Patch foraging total patch changes 18 sec2.02.54.11.71.6-1.92.01.91.71.70.10.4
Patch foraging total patch changes 24 sec2.22.74.41.92.1-1.91.81.91.71.50.60.8
Patch foraging total patch changes 6 sec0.40.51.40.50.6-0.91.20.80.60.2-0.7-0.5
Patch foraging time to switch 0 sec0.40.61.8-0.2-0.50.6-0.8-0.4-0.40.91.31.3
Patch foraging water rate 0 sec0.10.20.30.40.4-0.50.50.50.50.4-0.0-0.1
Patch foraging water rate 12 sec0.10.20.40.50.6-0.40.40.40.4-0.3-0.4-0.4
Patch foraging water rate 18 sec0.10.10.30.20.30.2-0.4-0.20.1-0.5-0.1-0.3
Patch foraging water rate 24 sec0.50.71.11.11.0-0.90.70.91.00.80.0-0.0
Patch foraging water rate 6 sec0.20.30.50.40.7-0.60.60.40.6-0.4-0.7-0.6
Seeking ratio, delayed vs. immediate footshock1.82.13.9-1.3-2.01.5-1.2-1.7-1.5-1.5-0.9-0.9
Distance traveled before self-admin0.40.40.9-0.6-0.00.3-0.6-0.3-0.90.50.90.8
Distance traveled after self-admin0.50.61.9-1.0-0.50.7-0.8-0.7-1.4-0.10.40.3
Extensor digitorum longus weight0.20.71.2-0.7-0.80.9-1.1-0.7-0.8-0.10.90.9
Bone: elastic displacement0.30.31.00.20.2-0.1-0.20.10.10.71.01.0
Bone: elastic work0.20.30.70.70.8-0.50.20.50.50.40.50.5
Bone: endosteal estimation0.10.10.30.20.1-0.40.50.30.2-0.0-0.6-0.5
Bone: endosteal perimeter0.91.92.6-1.6-1.51.5-1.3-1.5-1.6-1.4-0.7-0.9
Epididymis fat weight0.10.30.60.70.8-0.60.50.70.3-0.0-0.5-0.7
Delta time in closed arm before/after self-admin0.30.30.7-0.2-0.40.5-0.3-0.8-0.0-0.8-0.6-0.5
Delta time in open arm before/after self-admin0.10.10.30.00.4-0.50.50.40.10.2-0.3-0.3
Diff in mean of infusions in LGA sessions0.91.03.20.70.10.2-0.50.10.61.21.81.7
Delay discount exponential model param1.71.82.71.61.6-1.41.11.41.31.60.91.0
Extinction: sum of active levers before priming0.20.20.50.40.0-0.20.40.30.1-0.3-0.7-0.7
Active lever presses in extinction session 60.40.40.90.50.6-0.71.00.70.1-0.3-0.7-0.5
Bone: final force0.71.11.91.41.2-0.90.61.11.01.21.00.8
Bone: final moment0.81.42.41.61.4-1.00.61.31.11.31.00.9
Food consumed during 24 hour testing period0.91.12.11.31.4-1.31.11.21.20.5-0.2-0.2
Glucose0.30.51.10.60.7-0.81.10.50.6-0.2-0.8-0.6
Heart weight2.13.04.62.12.0-1.61.11.71.92.11.41.3
Delay discount hyperbolic model param1.71.82.61.61.5-1.41.11.41.31.61.01.0
Intermittent access intake day 1-15 change1.41.42.6-1.0-0.81.0-1.4-0.8-1.30.71.61.6
Intermittent access intake escalation1.21.22.0-1.0-0.81.0-1.3-0.8-1.30.51.41.4
Intermittent access intake escalation 20.70.72.1-0.4-0.20.3-0.7-0.2-0.91.01.51.3
Intermitt. access day 1 inactive lever presses0.10.10.30.10.1-0.00.00.10.10.30.40.5
Intermitt. access day 15 inactive lever presses0.70.81.4-0.7-0.71.0-1.2-0.6-1.0-0.01.11.0
Intermitt. access escalation Index0.20.20.60.00.2-0.20.30.10.1-0.6-0.8-0.8
Intermittent access day 1 total infusions0.00.10.20.1-0.50.10.00.10.1-0.2-0.3-0.3
Intermittent access day 15 total infusions0.40.50.9-0.7-0.80.7-0.8-0.5-0.90.10.70.6
Intermittent access terminal intake (last 3 days)0.20.20.5-0.5-0.60.4-0.4-0.2-0.7-0.00.30.2
Intermittent access total infusions0.30.40.9-0.7-1.00.7-0.7-0.5-0.8-0.30.10.0
Intermittent access day 1 locomotion0.10.10.3-0.2-0.60.3-0.1-0.1-0.1-0.5-0.5-0.5
Intermittent access day 15 total locomotion0.91.01.5-1.2-1.10.8-0.6-1.0-1.2-1.0-0.9-0.8
Intermittent access total locomotion1.11.31.8-1.3-1.30.9-0.6-1.0-1.3-1.3-1.1-1.1
Intermittent access standard deviation1.11.23.90.20.1-0.0-0.40.4-0.61.62.01.9
Left kidney weight1.13.25.81.51.8-1.61.91.41.3-1.4-2.4-2.4
Right kidney weight0.71.95.40.60.9-0.91.30.70.5-1.5-2.3-2.3
Cocaine induced anxiety0.40.41.4-0.0-0.40.5-0.6-0.00.10.51.21.2
Post-drug Anxiety0.10.10.30.0-0.20.3-0.4-0.10.30.30.60.5
Baseline Anxiety0.70.71.1-1.1-0.70.8-0.6-1.0-1.0-0.9-0.7-0.7
Tail length4.814.422.74.84.3-4.44.14.34.53.40.60.9
Length with tail6.323.235.56.05.7-5.65.15.65.54.31.31.5
Length without tail4.39.514.63.73.8-3.53.13.73.22.81.11.2
Times rat made contact with spout0.60.71.11.00.9-0.80.70.80.91.10.60.7
Lifetime Intake0.30.40.9-0.7-1.00.6-0.6-0.5-0.8-0.4-0.2-0.2
Liver weight, left0.20.30.70.30.1-0.50.80.40.60.0-0.7-0.6
Liver weight, right1.22.03.41.61.5-1.71.91.61.60.1-1.0-0.8
Locomotor activity4.16.510.13.23.2-2.92.82.93.12.00.50.6
Locomotor testing distance3.35.68.83.02.9-2.82.72.82.81.50.20.3
Locomotor testing rearing0.20.31.00.40.3-0.30.30.30.50.80.91.0
Locomotion in novel chamber0.20.20.5-0.3-0.40.4-0.5-0.4-0.50.20.70.7
Locomotion in novel chamber post-restriction0.50.61.10.71.1-1.01.10.60.60.1-0.9-0.8
Fecal boli incidents, locomotor time 10.60.71.41.20.6-0.70.60.81.01.00.70.7
Change in fecal boli incidents, locomotor task0.10.10.4-0.30.2-0.00.1-0.0-0.0-0.6-0.6-0.6
Time >=10cm from walls, locomotor time 10.60.61.2-0.8-0.50.3-0.1-0.7-0.9-1.0-1.1-1.1
Bouts of movement, locomotor time 10.10.10.30.50.4-0.20.20.30.50.40.40.5
Total resting periods, locomotor time 10.10.10.20.50.3-0.10.10.20.40.30.30.4
Rest time, locomotor task time 10.40.40.8-0.4-0.90.7-0.6-0.9-0.5-0.7-0.4-0.3
Distance moved, locomotor task time 11.01.11.81.01.3-1.20.91.11.01.20.70.7
Vertical activity count, locomotor time 10.70.71.11.01.1-1.00.90.90.90.90.40.4
Time >=10cm from walls, locomotor time 20.90.91.51.21.0-1.21.11.01.00.8-0.00.0
Bouts of movement, locomotor time 20.10.10.2-0.4-0.10.3-0.40.0-0.30.20.40.3
Total resting periods, locomotor time 20.20.20.4-0.7-0.40.6-0.7-0.3-0.5-0.10.30.2
Rest time, locomotor task time 20.10.10.10.3-0.30.2-0.1-0.20.4-0.3-0.3-0.2
Distance moved, locomotor task time 20.60.71.20.61.1-1.00.81.00.41.00.50.5
Vertical activity count, locomotor time 20.00.00.1-0.00.3-0.30.20.2-0.20.30.10.0
Light reinforcement 10.40.81.61.31.0-1.01.01.01.10.60.00.1
Light reinforcement 20.71.02.7-0.4-0.40.30.0-0.6-0.4-1.6-1.7-1.6
Bone: marrow area0.10.20.40.20.2-0.40.60.30.3-0.1-0.6-0.6
Bone: maximum diameter0.40.71.6-0.7-0.81.0-1.3-0.8-0.80.00.80.6
Bone: maximum force0.50.81.41.21.0-0.90.71.00.91.00.70.6
Bone: maximum moment0.50.91.71.31.1-1.00.71.11.01.10.70.6
Mean time between licks in bursts1.21.72.3-1.5-1.31.4-1.3-1.4-1.5-1.5-0.7-0.9
Mean num. licks in bursts1.11.32.20.91.2-1.31.51.01.0-0.3-1.4-1.3
Cd content in liver3.33.68.11.91.4-1.51.21.61.82.82.12.2
Co content in liver0.10.10.3-0.3-0.20.3-0.5-0.2-0.30.40.40.2
Cu content in liver3.23.96.52.52.1-2.32.32.22.51.70.10.2
Fe content in liver2.53.08.01.71.2-1.41.11.71.72.81.71.8
K content in liver1.11.11.61.31.1-1.01.00.91.1-0.4-1.2-1.2
Mg content in liver0.80.83.00.20.2-0.00.1-0.10.1-1.3-1.6-1.7
Mn content in liver1.01.12.70.61.0-0.91.10.80.5-0.8-1.6-1.6
Na content in liver0.50.50.90.70.5-0.80.90.80.80.9-0.1-0.0
Rb content in liver2.53.19.51.20.6-1.00.61.31.33.12.42.5
Se content in liver0.20.20.50.50.5-0.30.3-0.00.4-0.4-0.7-0.7
Sr content in liver0.50.51.6-0.00.3-0.00.1-0.2-0.1-1.3-1.1-1.1
Zn content in liver3.43.86.52.62.3-2.32.32.12.41.2-0.4-0.3
Bone: minimum diameter0.40.81.1-1.0-0.91.0-1.0-1.0-1.1-0.8-0.2-0.4
Time in familiar zone, hab. session 11.61.52.1-1.1-1.41.3-1.4-1.2-0.90.71.41.4
Time in novel zone, hab. session 10.60.61.00.71.0-0.90.91.00.6-0.1-0.5-0.5
Total zone transitions, hab. session 11.11.54.00.61.0-0.91.10.80.5-1.3-2.0-2.0
Total locomotion distance, hab. session 10.40.61.20.60.7-0.60.70.60.6-0.7-1.1-1.1
Locomotion velocity, hab. session 10.60.81.70.60.8-0.70.90.60.6-0.8-1.3-1.3
Time in familiar zone, hab. session 20.70.81.5-0.8-0.91.0-1.2-0.9-0.70.20.90.8
Time in novel zone, hab. session 20.10.10.30.10.2-0.40.50.30.00.0-0.4-0.3
Total zone transitions, hab. session 20.50.61.90.10.4-0.10.20.2-0.1-1.3-1.3-1.4
Total locomotion distance, hab. session 20.50.61.20.80.8-0.70.80.50.7-0.7-1.1-1.1
Locomotion velocity, hab. session 20.50.71.60.70.7-0.60.70.50.6-0.9-1.2-1.2
Novel to familiar place preference ratio1.71.84.60.70.9-1.21.70.80.8-0.8-2.2-1.9
Novelty place preference1.91.94.90.70.9-1.31.80.80.8-0.8-2.2-2.0
Time in novel zone, NPP test1.61.73.60.91.0-1.41.81.00.9-0.5-1.9-1.6
Total zone transitions, NPP test3.04.38.11.72.1-1.82.11.71.4-1.6-2.8-2.8
Total locomotion distance, NPP test1.11.52.01.31.4-1.21.31.21.2-0.6-1.2-1.2
Locomotion velocity, NPP test1.31.82.51.41.5-1.31.41.21.2-0.8-1.6-1.6
Intraocular pressure1.21.63.51.20.9-1.31.31.11.71.90.60.9
Delta distance traveled before/after self-admin0.10.10.1-0.3-0.30.2-0.0-0.2-0.3-0.4-0.4-0.4
Delta ambulatory time before/after self-admin0.30.30.60.60.6-0.60.80.60.60.2-0.2-0.2
Parametrial fat weight0.81.62.61.41.5-1.61.61.51.40.6-0.4-0.3
Pavlov. Cond. lever latency4.05.17.22.62.5-2.72.62.62.52.40.40.6
Pavlov. Cond. magazine entry latency4.86.29.7-2.9-2.93.1-3.1-2.8-2.8-1.80.30.1
Pavlov. Cond. change in total contacts1.41.52.5-1.4-1.41.5-1.6-1.4-1.3-0.30.80.7
Pavlov. Cond. index score4.76.09.5-2.9-2.83.0-3.1-2.8-2.8-1.80.40.1
Pavlov. Cond. latency score4.76.08.9-2.9-2.83.0-3.0-2.8-2.8-2.10.1-0.2
Pavlov. Cond. lever contacts2.22.63.7-1.8-1.71.9-1.9-1.9-1.8-1.7-0.3-0.5
Pavlov. Cond. magazine entry number5.46.710.33.13.1-3.23.23.02.91.7-0.4-0.2
Pavlov. Cond. intertrial magazine entries0.20.30.50.70.6-0.60.70.40.60.4-0.2-0.1
Pavlov. Cond. lever-magazine prob. diff.4.35.49.3-2.7-2.72.9-3.0-2.7-2.6-1.50.70.4
Pavlov. Cond. response bias5.26.310.2-2.9-2.93.1-3.2-2.9-2.8-1.80.50.2
Pavlov. Cond. lever latency0.20.30.5-0.5-0.70.5-0.5-0.6-0.40.20.40.5
Pavlov. Cond. magazine entry latency0.20.30.7-0.4-0.30.5-0.6-0.5-0.5-0.8-0.3-0.4
Pavlov. Cond. change in total contacts1.21.73.21.71.8-1.51.31.61.50.5-0.2-0.3
Pavlov. Cond. index score0.10.10.30.20.3-0.0-0.10.10.0-0.6-0.3-0.5
Pavlov. Cond. latency score0.10.10.40.10.30.0-0.10.0-0.0-0.6-0.4-0.5
Pavlov. Cond. lever contacts0.60.81.41.01.2-1.01.01.00.8-0.1-0.6-0.6
Pavlov. Cond. magazine entry number0.40.50.80.70.6-0.80.80.80.80.90.30.4
Pavlov. Cond. intertrial magazine entries0.40.50.8-0.9-0.90.6-0.6-0.6-0.70.60.80.8
Pavlov. Cond. lever-magazine prob. diff.0.10.10.50.10.30.0-0.10.1-0.0-0.7-0.4-0.5
Pavlov. Cond. response bias0.10.10.50.10.3-0.0-0.00.1-0.1-0.7-0.5-0.6
Time in closed arm before self-admin0.81.01.80.71.2-1.21.11.30.71.10.50.6
Time in closed arm after self-admin0.00.00.00.0-0.00.0-0.1-0.20.20.00.10.2
Time in open arm before self-admin0.60.71.3-0.8-1.21.0-0.9-1.1-0.8-0.6-0.1-0.1
Time in open arm after self-admin0.80.92.5-0.9-0.50.20.2-0.5-0.7-1.2-1.6-1.6
Bone: periosteal estimation0.00.00.00.0-0.00.1-0.2-0.0-0.10.10.20.1
Bone: periosteal perimeter0.91.52.4-1.4-1.41.5-1.5-1.4-1.5-0.80.0-0.2
Bone: post-yield work0.00.10.10.20.2-0.20.20.00.1-0.4-0.4-0.4
Progressive ratio test 1 active lever presses0.10.10.5-0.2-0.1-0.00.30.1-0.1-0.5-0.7-0.6
Progressive ratio test 1 breakpoint0.20.20.5-0.3-0.20.00.20.0-0.1-0.6-0.7-0.6
Progressive ratio test 1 inactive lever presses0.40.40.8-0.6-0.60.8-0.9-0.4-0.5-0.00.80.8
Progressive ratio test 2 active lever presses0.50.61.0-0.9-1.00.9-0.8-0.7-1.0-0.5-0.1-0.2
Progressive ratio test 2 breakpoint0.30.40.7-0.7-0.80.7-0.7-0.5-0.8-0.30.0-0.0
Progressive ratio test 2 inactive lever presses1.51.73.5-1.2-1.41.6-1.9-1.1-1.4-0.21.31.0
Incentive Sensitization - Responses1.01.01.8-1.2-1.21.3-1.4-1.1-1.2-0.40.40.3
Incentive Sensitization - Breakpoint1.01.01.8-1.1-1.21.3-1.3-1.0-1.2-0.30.40.3
Sum of active levers in priming session hrs 5-60.50.50.90.90.7-0.91.00.90.40.3-0.3-0.2
Progressive ratio2.63.05.02.22.0-2.22.21.91.81.3-0.2-0.1
Food seeking constrained by brief footshock0.81.02.2-1.4-0.71.0-1.0-1.2-1.5-0.8-0.1-0.1
Seeking ratio, punishment vs. effort4.25.28.7-2.9-2.42.7-2.8-2.7-2.6-1.60.40.2
Retroperitoneal fat weight0.41.21.91.01.1-1.31.41.10.9-0.1-1.2-1.3
Reaction time number correct0.50.81.3-1.1-1.10.9-1.0-1.1-1.1-0.10.30.2
Reaction time mean minus median0.20.20.50.50.7-0.30.40.20.5-0.5-0.5-0.5
Reaction time mean minus median AUC0.30.40.80.70.8-0.60.70.40.9-0.3-0.4-0.3
Reaction time num false alarms0.20.30.6-0.8-0.70.6-0.5-0.4-0.70.20.40.4
Reaction time num false alarms AUC0.00.10.2-0.5-0.30.1-0.0-0.0-0.40.30.00.1
Reaction time trials correct on left0.50.81.3-1.1-1.10.9-1.0-1.1-1.1-0.10.30.2
Reaction time trials on left0.60.81.4-1.2-1.10.9-1.0-1.2-1.1-0.10.30.2
Reaction time mean0.10.10.4-0.0-0.0-0.10.1-0.0-0.2-0.3-0.6-0.6
Reaction time mean AUC0.10.20.6-0.1-0.1-0.00.2-0.1-0.2-0.4-0.8-0.8
Median of all reaction times0.10.10.4-0.2-0.2-0.00.1-0.0-0.5-0.1-0.5-0.6
Reaction time omissions0.20.30.5-0.5-0.60.4-0.4-0.4-0.60.70.70.7
Reaction time false alarm rate0.00.00.1-0.00.0-0.00.10.30.00.40.20.2
Reaction time premature initiation rate1.62.13.91.71.9-1.81.72.01.31.00.20.2
Reaction time premature initiations0.60.81.60.91.2-1.11.01.30.60.80.30.3
Std. dev. reaction times0.20.30.70.40.5-0.40.60.30.3-0.4-0.8-0.8
Reaction time trials completed0.60.81.4-1.2-1.10.9-1.0-1.2-1.1-0.10.30.2
Reaction time trials AUC0.71.01.7-1.3-1.21.0-1.1-1.3-1.3-0.20.20.1
Run reversals in cocaine runway, females2.01.93.5-1.9-1.21.6-1.7-1.9-1.6-1.00.10.1
Run reversals in cocaine runway, males1.11.12.11.00.8-0.80.51.10.71.41.31.3
Latency to leave start box in cocaine runway0.60.61.31.00.9-0.80.70.81.10.70.30.3
Latency to leave start box in cocaine runway, F1.51.72.71.41.4-1.10.71.21.41.61.31.3
Latency to leave start box in cocaine runway, M0.50.41.5-0.1-0.30.20.1-0.2-0.1-0.9-1.2-1.2
Std. dev. time between licks in bursts4.14.98.4-2.4-2.52.7-2.9-2.5-2.4-0.61.41.2
Total sessions with >9 infusions0.50.51.4-0.2-0.60.6-0.8-0.4-0.20.51.21.2
Short access day 1 total inactive lever presses4.04.47.0-2.6-2.62.6-2.5-2.5-2.1-1.40.20.2
Short access day 10 total inactive lever presses1.31.55.20.40.30.2-0.60.20.21.52.32.3
Short access day 1 total infusions0.80.81.8-1.0-1.41.2-1.2-1.0-0.6-0.50.10.1
Short access day 10 total infusions0.10.10.3-0.4-0.50.2-0.1-0.2-0.6-0.3-0.3-0.3
Short access total infusions0.70.81.3-1.1-1.20.8-0.7-0.9-1.0-0.9-0.6-0.5
Short access day 1 locomotion0.00.00.1-0.1-0.20.2-0.2-0.2-0.10.00.20.3
Short access day 10 total locomotion0.20.20.9-0.10.1-0.30.50.1-0.1-0.4-0.9-0.8
Short access total locomotion0.10.10.5-0.10.0-0.20.40.20.2-0.4-0.7-0.5
One hour access (0.3 mA shock)0.40.50.8-0.7-0.70.4-0.2-0.5-0.7-0.8-0.9-0.9
Compulsive drug intake0.80.82.4-0.5-0.30.20.1-0.7-0.1-1.3-1.6-1.5
One hour access (shock baseline)0.10.10.3-0.1-0.30.2-0.20.2-0.40.40.50.5
Social response proportion0.50.61.10.40.8-0.80.70.70.41.00.80.9
Social responses0.40.50.70.70.9-0.80.80.80.80.30.00.1
Social time0.60.81.5-0.7-0.70.9-1.2-0.7-0.80.21.21.1
Soleus weight2.47.112.43.53.4-3.12.83.13.21.80.20.3
Bone: stiffness0.10.20.30.50.4-0.40.40.50.30.50.20.2
Tibialis anterior weight0.00.00.20.20.10.0-0.2-0.0-0.10.10.40.4
Time to tail flick, vehicle, before self-admin1.51.52.41.51.2-1.41.31.51.60.90.30.5
Time to tail flick, vehicle, after self-admin1.21.32.50.91.0-0.80.51.20.81.61.51.4
Time to tail flick, test, before self-admin0.60.61.90.30.4-0.60.90.30.4-0.6-1.4-1.3
Time to tail flick, test, after self-admin0.20.20.7-0.1-0.30.2-0.30.0-0.20.40.80.8
Delta time to tail flick, vehicle, before/after SA0.50.50.9-0.6-0.50.7-0.9-0.4-0.80.40.90.8
Delta time to tail flick, test, before/after SA0.40.40.7-0.5-0.60.7-0.8-0.3-0.60.20.80.7
Tibia length4.412.422.14.64.7-4.23.94.14.01.3-0.6-0.5
Ambulatory time before self-admin0.50.51.4-0.6-0.30.6-0.8-0.5-1.20.20.80.6
Ambulatory time after self-admin0.20.31.5-0.8-0.10.2-0.2-0.3-1.2-0.3-0.1-0.1
Bone: tissue strength2.22.13.11.71.6-1.41.01.61.51.71.21.1
Total heroin consumption1.01.21.91.21.2-1.00.71.01.01.41.11.1
Bone: trabecular number1.11.74.0-1.3-0.90.8-0.3-1.1-1.1-2.0-1.7-1.6
Bone: trabecular spacing1.52.04.01.61.2-1.10.61.31.42.01.61.5
Bone: trabecular thickness0.70.82.50.10.3-0.30.6-0.00.1-1.3-1.6-1.5
Bone: trabecular tissue density0.20.30.60.70.6-0.70.70.60.70.4-0.1-0.1
Water consumed over 24 hours0.20.20.80.10.10.2-0.5-0.00.00.50.90.8
Number of responses in last shaping day0.50.51.1-0.7-0.81.0-1.1-0.6-0.6-0.10.70.5