Hub : Genes

Plxnb1

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 BLA gene expression Plxnb1 0.1 0.08 5.4e-05 0.1 0.06 0.11 0.11 9.6e-06 2.6e-04 2.0e-06 1.2e-06
2 pVTA gene expression Plxnb1 0.17 0.1 6.4e-15 0.18 0.18 0.18 0.18 1.5e-14 2.1e-14 2.5e-14 3.6e-14
3 NAcc gene expression Plxnb1 0.08 0.06 3.2e-12 0.08 0.08 0.08 0.08 1.9e-12 1.4e-12 1.3e-12 1.0e-12
4 Brain gene expression Plxnb1 0.21 0.11 0.0e+00 0.22 0.2 0.21 0.21 2.7e-20 6.4e-18 6.3e-19 1.6e-19
5 LHb gene expression Plxnb1 0.26 0.16 1.1e-03 0.08 0.06 0.07 0.08 7.2e-03 1.6e-02 9.3e-03 6.7e-03
6 Liver gene expression Plxnb1 0.12 0.06 5.6e-17 0.11 0.12 0.11 0.11 8.3e-12 8.5e-13 3.1e-12 3.7e-12
7 RMTg gene expression Plxnb1 0.18 0.13 3.3e-03 -0.01 0.03 0.01 0.01 8.7e-01 6.5e-02 2.1e-01 1.9e-01
8 Adipose gene expression Plxnb1 0.45 0.14 0.0e+00 0.13 0.22 0.22 0.2 1.3e-14 1.4e-23 1.5e-23 1.1e-21
9 Adipose isoform ratio XM_039081606.2 0.13 0.08 4.0e-04 0 0.02 0.02 0 2.3e-01 1.5e-03 3.2e-03 7.8e-02
10 Adipose alternative TSS XM_039081606.2 0.12 0.08 1.5e-03 -0 0.01 0 -0 9.5e-01 1.5e-02 1.3e-01 9.4e-01

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10
Bone: apparent density0.20.31.20.2-0.0-0.00.20.10.6-1.10.01.10.8
Area under the delay curve1.41.62.71.41.41.31.21.3-0.8-0.11.21.61.6
BMI with tail0.10.30.9-0.6-0.9-0.4-0.5-0.20.30.10.80.60.9
BMI without tail0.51.52.2-1.5-1.5-1.3-1.5-1.21.4-1.4-0.20.70.7
Body weight3.113.623.9-4.8-4.9-4.5-4.4-4.13.7-1.9-2.8-2.1-2.0
Weight adjusted by age0.10.20.7-0.3-0.0-0.3-0.40.1-0.30.6-0.2-0.9-0.6
Bone surface0.20.30.80.50.40.50.70.5-0.30.00.70.80.9
Bone volume0.10.20.80.30.20.30.60.30.0-0.40.50.90.8
Breakpoint value in progressive ratio session0.10.10.20.20.30.20.30.1-0.1-0.20.20.50.4
Number of licking bursts0.40.72.40.40.70.50.60.3-1.11.50.2-1.2-0.9
Context. condit. distance diff. score0.00.00.0-0.1-0.0-0.0-0.0-0.1-0.10.20.0-0.1-0.1
Locomotion velocity, session 10.10.10.40.30.00.20.10.30.1-0.30.30.60.6
Locomotion distance, session 10.91.12.0-1.0-1.4-1.0-1.2-0.81.3-1.3-0.10.90.8
Locomotion velocity, session 20.40.51.10.60.40.60.40.8-0.60.61.00.60.9
Locomotion distance, session 20.50.72.60.3-0.20.2-0.00.50.3-0.70.91.61.6
Locomotion velocity, session 30.70.82.7-0.2-0.6-0.2-0.1-0.10.7-1.10.61.61.6
Locomotion distance, session 31.71.84.61.10.91.21.21.2-0.7-0.01.72.02.2
Stereotopy head waving bouts, day 30.60.72.6-0.2-0.0-0.1-0.2-0.2-0.61.3-0.3-1.6-1.3
Stereotopy head waving duration, day 30.60.72.4-0.6-0.3-0.5-0.6-0.60.10.5-0.9-1.5-1.5
Locomotion velocity, session 70.40.41.7-0.2-0.3-0.4-0.2-0.20.8-1.3-0.30.80.5
Locomotion distance, session 71.01.32.21.31.01.11.21.2-0.6-0.01.11.51.4
Stereotopy head waving bouts, day 70.00.00.10.0-0.0-0.1-0.20.00.2-0.3-0.10.10.1
Stereotopy head waving duration, day 70.40.40.7-0.7-0.7-0.7-0.9-0.60.8-0.8-0.60.0-0.1
Locomotion velocity, session 80.50.61.7-0.5-0.8-0.4-0.6-0.20.8-1.00.51.31.3
Locomotion distance, session 80.91.34.1-0.5-0.8-0.3-0.6-0.21.0-1.50.62.01.9
Degree of sensitization distance1.31.32.4-1.1-0.9-1.2-1.0-1.21.0-0.6-1.5-1.3-1.5
Degree of sensitization stereotypy0.30.31.1-0.2-0.3-0.4-0.4-0.20.7-1.1-0.30.60.3
Conditioned locomotion2.32.74.12.02.01.91.91.8-1.40.51.41.51.4
Cocaine response after cond. corrected0.70.93.1-0.7-0.5-0.5-0.6-0.7-0.21.1-0.5-1.8-1.4
Cocaine response after cond. not corrected1.61.93.2-1.7-1.4-1.4-1.4-1.50.70.2-1.1-1.8-1.6
Cocaine response before conditioning1.01.22.0-1.2-1.4-1.2-1.0-1.11.4-1.4-0.60.50.3
Saline control response0.91.22.6-1.0-1.0-1.2-0.8-1.11.5-1.6-1.4-0.1-0.6
Bone: connectivity density0.40.61.60.80.70.60.70.50.1-1.00.11.30.9
Bone: cortical apparent density0.10.20.40.50.40.40.40.4-0.2-0.20.30.60.5
Bone: cortical area0.40.62.70.40.50.50.40.4-1.11.60.4-1.1-0.6
Bone: cortical porosity0.40.41.80.40.50.20.30.10.5-1.3-0.21.10.6
Bone: cortical porosity0.30.41.70.30.40.20.30.10.5-1.3-0.40.90.4
Bone: cortical thickness0.50.83.0-0.4-0.3-0.3-0.3-0.3-0.61.5-0.2-1.7-1.3
Bone: cortical thickness0.10.10.20.10.10.10.20.1-0.30.5-0.0-0.5-0.4
Bone: cortical tissue density0.10.20.40.50.40.40.40.4-0.1-0.20.30.60.5
Condit. Reinf. active minus inactive responses0.40.41.6-0.1-0.2-0.4-0.4-0.2-0.10.5-0.7-1.3-1.2
Condit. Reinf. active-inactive response ratio0.80.93.3-0.3-0.4-0.6-0.5-0.4-0.00.7-1.0-1.8-1.7
Condit. Reinf. active responses0.10.10.40.00.20.1-0.0-0.0-0.40.6-0.1-0.7-0.6
Condit. Reinf. inactive responses0.60.71.30.60.90.90.70.6-0.60.21.01.11.2
Incentive salience index mean0.10.10.40.30.20.20.10.3-0.40.60.1-0.4-0.2
Condit. Reinf. lever presses1.21.62.31.41.21.41.41.3-1.30.91.51.01.2
Condit. Reinf. active minus inactive responses0.91.12.3-1.3-1.5-1.3-1.2-1.11.0-0.3-0.8-0.8-0.7
Condit. Reinf. active-inactive response ratio0.80.92.0-1.2-1.4-1.2-1.2-1.00.9-0.2-0.6-0.7-0.6
Condit. Reinf. active responses0.91.22.1-1.3-1.4-1.3-1.1-1.21.0-0.4-1.0-1.0-1.0
Condit. Reinf. inactive responses0.10.10.10.40.30.20.40.3-0.20.3-0.0-0.2-0.3
Condit. Reinf. lever presses1.21.73.2-1.6-1.8-1.5-1.7-1.41.4-0.7-0.9-0.6-0.6
Condit. Reinf. lever reinforcers received1.11.62.6-1.4-1.6-1.5-1.3-1.31.2-0.5-1.2-1.1-1.1
Conditioned reinforcement - actives1.52.54.81.92.21.61.71.7-1.81.31.50.70.9
Conditioned reinforcement - inactives2.43.57.72.01.81.91.82.0-2.52.81.6-0.50.1
Conditioned locomotion0.40.50.90.90.90.60.60.8-0.2-0.30.51.00.8
Patch foraging indifference point 0 sec1.22.33.8-1.6-1.4-1.7-1.5-1.41.9-2.0-1.7-0.3-0.8
Patch foraging indifference point AUC0.20.31.1-0.1-0.3-0.1-0.2-0.10.6-1.00.11.10.9
Delay disc. indifference point, 0s delay0.00.00.1-0.0-0.00.1-0.1-0.10.1-0.3-0.00.20.2
Delay disc. indifference point, 16s delay0.80.91.41.11.00.90.91.2-0.60.00.91.11.1
Delay disc. indifference point, 2s delay0.20.20.30.50.50.40.40.4-0.3-0.10.40.60.6
Delay disc. indifference point, 24s delay0.80.91.31.11.01.11.01.1-0.6-0.00.91.11.1
Delay disc. indifference point, 4s delay1.11.21.61.21.31.21.21.1-1.00.41.11.01.1
Delay disc. indifference point, 8s delay1.51.82.71.51.51.41.41.4-0.90.11.31.61.6
Indifference point function ln k0.50.81.70.70.60.90.71.0-0.70.61.30.91.2
Indifference point function log k0.50.81.70.70.60.90.71.0-0.70.61.30.91.2
Patch foraging total patch changes 0 sec1.32.43.3-1.7-1.5-1.8-1.5-1.51.8-1.7-1.8-0.6-1.1
Patch foraging total patch changes 12 sec0.91.21.7-1.3-1.2-1.2-1.1-1.11.2-0.9-1.3-0.7-0.9
Patch foraging total patch changes 18 sec1.82.84.3-1.6-1.6-1.8-1.6-1.62.0-2.0-2.1-0.6-1.2
Patch foraging total patch changes 24 sec1.52.63.9-1.7-2.0-1.9-1.8-1.61.7-1.1-1.6-1.0-1.2
Patch foraging total patch changes 6 sec0.50.72.8-0.5-0.6-0.8-0.7-0.51.2-1.7-0.90.50.0
Patch foraging time to switch 0 sec0.20.51.50.40.80.50.50.4-0.91.20.2-0.9-0.6
Patch foraging water rate 0 sec0.10.30.5-0.7-0.5-0.6-0.5-0.60.5-0.3-0.6-0.5-0.6
Patch foraging water rate 12 sec0.10.20.5-0.5-0.7-0.5-0.6-0.30.5-0.2-0.2-0.1-0.1
Patch foraging water rate 18 sec0.10.10.4-0.4-0.3-0.1-0.2-0.2-0.20.60.4-0.30.0
Patch foraging water rate 24 sec0.71.01.5-1.2-1.0-1.1-1.1-1.20.7-0.3-0.9-0.9-0.9
Patch foraging water rate 6 sec0.20.30.7-0.7-0.8-0.5-0.6-0.80.8-0.6-0.30.20.1
Seeking ratio, delayed vs. immediate footshock1.62.03.51.31.91.61.51.2-1.00.11.41.71.6
Distance traveled before self-admin0.50.72.10.70.80.80.80.8-1.11.50.6-0.6-0.3
Distance traveled after self-admin0.30.40.80.60.60.70.60.4-0.80.90.6-0.10.1
Extensor digitorum longus weight0.20.61.40.60.70.71.10.7-1.01.20.7-0.3-0.0
Bone: elastic displacement0.30.31.2-0.2-0.2-0.3-0.1-0.2-0.10.6-0.4-1.1-1.0
Bone: elastic work0.20.30.6-0.8-0.6-0.6-0.6-0.60.20.4-0.2-0.7-0.5
Bone: endosteal estimation0.10.20.9-0.3-0.1-0.2-0.2-0.30.6-1.0-0.30.50.3
Bone: endosteal perimeter0.91.92.61.61.51.61.31.5-1.30.61.51.31.4
Epididymis fat weight0.20.60.9-0.9-0.8-0.9-0.9-0.80.7-0.3-0.7-0.7-0.7
Delta time in closed arm before/after self-admin0.50.40.80.70.50.90.90.8-0.50.30.60.70.6
Delta time in open arm before/after self-admin0.20.20.3-0.6-0.3-0.5-0.6-0.60.4-0.3-0.4-0.3-0.3
Diff in mean of infusions in LGA sessions0.50.72.5-0.5-0.4-0.3-0.3-0.5-0.51.3-0.2-1.6-1.2
Delay discount exponential model param1.51.72.7-1.5-1.5-1.3-1.3-1.40.90.0-1.3-1.7-1.6
Extinction: sum of active levers before priming0.10.10.50.10.20.00.10.00.2-0.70.00.70.5
Active lever presses in extinction session 60.30.31.1-0.0-0.6-0.4-0.3-0.00.7-1.1-0.20.70.5
Bone: final force1.01.62.7-1.6-1.4-1.4-1.5-1.40.70.1-0.9-1.5-1.2
Bone: final moment1.11.83.0-1.7-1.5-1.5-1.6-1.40.70.2-0.9-1.6-1.3
Food consumed during 24 hour testing period1.01.32.1-1.3-1.4-1.4-1.4-1.21.1-0.6-1.0-0.8-0.8
Glucose0.81.32.3-1.3-1.3-1.1-1.0-1.21.5-1.5-0.80.40.2
Heart weight1.62.65.6-1.7-1.7-1.6-1.7-1.50.60.8-1.2-2.4-2.0
Delay discount hyperbolic model param1.71.92.6-1.5-1.6-1.4-1.4-1.41.0-0.1-1.3-1.6-1.6
Intermittent access intake day 1-15 change0.91.83.31.61.41.31.31.8-1.71.81.1-0.20.2
Intermittent access intake escalation1.22.44.21.81.61.61.52.0-1.92.11.3-0.20.2
Intermittent access intake escalation 20.91.03.20.90.80.70.71.2-1.21.80.5-1.0-0.6
Intermitt. access day 1 inactive lever presses0.10.21.00.30.30.30.20.3-0.71.00.2-0.7-0.4
Intermitt. access day 15 inactive lever presses0.91.84.01.41.31.21.31.5-1.92.01.2-0.40.1
Intermitt. access escalation Index0.20.31.00.1-0.00.00.00.00.4-1.00.11.00.8
Intermittent access day 1 total infusions0.20.30.90.70.90.50.50.7-0.70.40.50.20.3
Intermittent access day 15 total infusions1.62.44.31.91.91.51.52.1-1.91.71.40.10.5
Intermittent access terminal intake (last 3 days)1.11.53.01.61.61.11.21.7-1.41.11.10.30.5
Intermittent access total infusions1.61.93.31.71.81.31.31.8-1.71.41.20.20.5
Intermittent access day 1 locomotion0.10.10.6-0.10.0-0.4-0.4-0.10.4-0.7-0.30.30.1
Intermittent access day 15 total locomotion0.50.81.81.21.10.90.91.4-0.80.50.80.60.6
Intermittent access total locomotion1.01.12.31.41.41.01.01.5-0.80.30.90.90.9
Intermittent access standard deviation0.40.93.00.30.3-0.1-0.00.8-0.91.7-0.0-1.7-1.2
Left kidney weight0.42.03.7-1.9-1.9-1.7-1.6-1.51.7-1.2-1.0-0.3-0.4
Right kidney weight0.21.01.8-1.2-1.3-1.2-1.0-0.91.2-1.1-0.70.0-0.1
Cocaine induced anxiety0.30.40.7-0.8-0.5-0.8-0.8-0.80.3-0.2-0.6-0.7-0.6
Post-drug Anxiety0.10.10.2-0.3-0.2-0.3-0.3-0.40.1-0.1-0.2-0.2-0.2
Baseline Anxiety0.30.40.70.70.50.70.70.5-0.30.00.60.80.7
Tail length4.015.421.9-4.7-4.2-4.5-4.4-4.34.1-3.0-4.0-2.4-2.9
Length with tail6.528.441.9-6.5-6.2-6.2-6.0-5.85.1-2.6-5.1-4.3-4.4
Length without tail4.815.423.1-4.8-4.8-4.6-4.4-4.23.6-1.3-3.5-3.5-3.4
Times rat made contact with spout0.60.71.1-0.9-0.9-0.9-0.9-0.90.6-0.1-0.9-1.0-1.0
Lifetime Intake1.92.34.42.01.91.51.52.1-1.61.11.40.70.9
Liver weight, left0.61.01.5-1.1-1.0-1.1-0.8-1.11.2-1.2-1.1-0.2-0.5
Liver weight, right1.42.53.4-1.8-1.7-1.8-1.7-1.81.9-1.8-1.5-0.3-0.7
Locomotor activity4.57.110.3-3.2-3.1-3.1-3.1-2.92.7-1.9-2.6-1.6-1.8
Locomotor testing distance3.05.48.2-2.9-2.7-2.7-2.7-2.52.4-1.6-2.3-1.5-1.7
Locomotor testing rearing0.10.20.6-0.2-0.1-0.2-0.0-0.20.00.1-0.5-0.7-0.8
Locomotion in novel chamber0.20.31.00.40.30.40.20.6-0.61.00.3-0.6-0.4
Locomotion in novel chamber post-restriction0.30.41.0-0.7-1.0-0.5-0.6-0.31.0-0.9-0.60.2-0.0
Fecal boli incidents, locomotor time 10.50.71.2-1.1-0.6-0.7-0.8-1.00.5-0.3-0.9-0.9-0.9
Change in fecal boli incidents, locomotor task0.10.10.30.50.30.30.30.2-0.10.10.40.50.5
Time >=10cm from walls, locomotor time 10.30.40.90.70.40.60.60.7-0.1-0.30.50.90.8
Bouts of movement, locomotor time 10.10.10.4-0.5-0.3-0.3-0.2-0.60.2-0.1-0.2-0.2-0.2
Total resting periods, locomotor time 10.00.00.2-0.4-0.2-0.1-0.1-0.40.1-0.1-0.1-0.1-0.1
Rest time, locomotor task time 10.50.61.00.70.81.01.00.4-0.70.30.80.80.8
Distance moved, locomotor task time 10.81.21.9-1.1-1.3-1.2-1.3-1.00.8-0.0-1.1-1.4-1.3
Vertical activity count, locomotor time 10.41.01.9-1.4-1.1-1.1-1.0-1.20.9-0.4-1.0-0.9-0.9
Time >=10cm from walls, locomotor time 20.71.01.5-1.2-1.2-1.1-1.0-0.91.1-0.8-1.1-0.6-0.8
Bouts of movement, locomotor time 20.10.20.70.40.30.10.10.3-0.50.90.2-0.5-0.3
Total resting periods, locomotor time 20.10.20.70.60.60.40.30.5-0.70.80.4-0.2-0.0
Rest time, locomotor task time 20.10.10.2-0.10.30.20.3-0.2-0.1-0.30.20.50.4
Distance moved, locomotor task time 20.70.81.5-0.7-1.2-0.9-1.0-0.40.70.0-0.9-1.2-1.2
Vertical activity count, locomotor time 20.00.00.1-0.1-0.3-0.1-0.20.10.20.0-0.2-0.3-0.3
Light reinforcement 10.40.91.7-1.3-1.0-1.1-1.2-1.01.0-0.7-0.8-0.5-0.5
Light reinforcement 20.50.82.90.20.30.50.40.40.1-0.80.91.71.7
Bone: marrow area0.10.21.0-0.3-0.1-0.2-0.3-0.40.6-1.0-0.30.50.3
Bone: maximum diameter0.40.72.20.70.80.80.60.7-1.21.50.8-0.5-0.1
Bone: maximum force0.61.01.8-1.4-1.1-1.1-1.1-1.20.8-0.3-0.9-0.9-0.9
Bone: maximum moment0.61.01.8-1.4-1.1-1.2-1.2-1.10.8-0.2-0.8-1.0-0.9
Mean time between licks in bursts0.71.72.61.61.41.51.41.6-1.41.11.30.70.9
Mean num. licks in bursts0.81.23.1-0.9-1.2-1.0-1.1-0.91.5-1.8-0.80.70.3
Cd content in liver0.10.20.50.40.20.30.10.40.1-0.40.20.70.6
Co content in liver1.31.52.51.61.41.30.91.5-1.61.60.9-0.20.0
Cu content in liver3.54.27.0-2.6-2.2-2.2-2.4-2.52.1-1.5-1.9-1.1-1.3
Fe content in liver1.51.93.8-1.2-1.0-1.3-1.4-1.40.8-0.1-1.6-1.9-1.9
K content in liver0.40.40.8-0.8-0.5-0.3-0.9-0.50.5-0.60.20.60.7
Mg content in liver1.51.54.40.70.81.20.20.8-0.80.31.81.82.1
Mn content in liver0.60.72.70.0-0.30.1-0.60.20.5-1.00.61.61.5
Na content in liver0.90.91.8-0.9-0.6-0.9-1.2-0.90.9-0.8-1.3-0.8-1.1
Rb content in liver1.72.07.0-0.8-0.4-1.0-0.6-1.10.40.2-1.9-2.4-2.6
Se content in liver0.10.20.5-0.3-0.4-0.1-0.5-0.20.2-0.20.40.60.7
Sr content in liver1.41.24.90.2-0.30.4-0.20.50.1-0.41.52.02.2
Zn content in liver1.92.13.6-1.9-1.6-1.5-1.9-1.61.6-1.5-1.1-0.1-0.3
Bone: minimum diameter0.50.91.31.01.11.11.01.0-1.10.81.10.60.8
Time in familiar zone, hab. session 11.31.32.21.31.51.21.31.0-1.51.40.4-0.7-0.6
Time in novel zone, hab. session 10.60.61.1-1.0-1.0-0.9-1.0-0.80.9-0.7-0.5-0.0-0.1
Total zone transitions, hab. session 10.71.01.8-0.7-1.2-0.8-1.1-0.41.2-1.30.11.21.1
Total locomotion distance, hab. session 10.30.40.8-0.6-0.8-0.6-0.7-0.50.8-0.9-0.10.60.6
Locomotion velocity, hab. session 10.40.61.3-0.6-0.9-0.7-0.7-0.61.0-1.1-0.10.80.7
Time in familiar zone, hab. session 20.70.82.00.81.00.80.70.6-1.31.40.6-0.6-0.3
Time in novel zone, hab. session 20.10.10.6-0.1-0.2-0.2-0.1-0.00.5-0.8-0.40.30.1
Total zone transitions, hab. session 20.30.41.4-0.3-0.6-0.1-0.40.10.3-0.30.71.01.2
Total locomotion distance, hab. session 20.40.50.9-0.8-0.9-0.6-0.7-0.60.9-0.9-0.00.60.6
Locomotion velocity, hab. session 20.40.50.8-0.7-0.9-0.6-0.7-0.50.8-0.90.10.80.8
Novel to familiar place preference ratio1.71.87.4-0.9-0.8-0.9-0.9-0.91.8-2.7-0.91.50.8
Novelty place preference1.82.08.2-0.9-0.7-0.9-0.9-0.91.9-2.9-0.91.60.8
Time in novel zone, NPP test1.81.97.5-1.0-0.8-1.0-1.0-1.11.9-2.7-1.11.20.5
Total zone transitions, NPP test2.33.35.6-1.9-2.4-1.8-2.1-1.42.2-2.3-0.21.51.4
Total locomotion distance, NPP test0.91.32.4-1.3-1.6-1.2-1.4-1.11.4-1.2-0.40.40.4
Locomotion velocity, NPP test1.11.62.7-1.4-1.7-1.3-1.5-1.21.6-1.5-0.40.70.6
Intraocular pressure1.31.83.9-1.1-1.0-1.3-1.0-1.51.3-1.3-2.0-1.1-1.6
Delta distance traveled before/after self-admin0.20.20.5-0.3-0.3-0.3-0.4-0.40.5-0.7-0.20.40.3
Delta ambulatory time before/after self-admin0.81.01.5-1.1-1.1-1.0-1.1-1.21.2-1.2-0.80.1-0.1
Parametrial fat weight0.51.22.4-1.5-1.4-1.3-1.4-1.21.2-0.6-0.8-0.5-0.5
Pavlov. Cond. lever latency4.15.27.2-2.5-2.3-2.5-2.4-2.42.4-1.9-2.7-1.5-2.0
Pavlov. Cond. magazine entry latency6.48.210.93.33.23.33.13.1-3.22.73.01.31.8
Pavlov. Cond. change in total contacts1.41.52.41.51.41.31.31.3-1.61.51.0-0.10.1
Pavlov. Cond. index score5.57.09.42.92.93.02.92.8-3.12.72.81.01.5
Pavlov. Cond. latency score5.56.98.82.92.83.02.82.8-3.02.52.91.31.8
Pavlov. Cond. lever contacts2.42.94.41.81.61.81.81.8-1.81.62.11.11.5
Pavlov. Cond. magazine entry number6.38.010.9-3.3-3.2-3.2-3.1-3.13.3-2.8-2.8-0.9-1.4
Pavlov. Cond. intertrial magazine entries0.30.40.6-0.7-0.5-0.6-0.7-0.80.7-0.7-0.6-0.2-0.3
Pavlov. Cond. lever-magazine prob. diff.5.06.28.92.72.62.82.72.6-3.02.82.60.71.3
Pavlov. Cond. response bias6.07.49.93.02.93.12.92.9-3.12.82.91.11.7
Pavlov. Cond. lever latency0.30.40.90.80.90.60.80.6-0.70.40.2-0.1-0.1
Pavlov. Cond. magazine entry latency0.30.41.00.40.30.60.30.5-0.50.41.00.81.0
Pavlov. Cond. change in total contacts1.32.03.8-1.7-1.8-1.6-2.0-1.51.4-0.7-1.1-1.0-0.9
Pavlov. Cond. index score0.10.10.3-0.4-0.5-0.2-0.5-0.30.20.00.30.20.4
Pavlov. Cond. latency score0.10.10.3-0.3-0.4-0.0-0.4-0.10.10.10.40.30.5
Pavlov. Cond. lever contacts0.50.71.2-1.0-1.1-0.9-1.0-0.81.0-0.8-0.50.10.0
Pavlov. Cond. magazine entry number0.30.40.8-0.5-0.4-0.7-0.4-0.50.5-0.4-0.9-0.7-0.9
Pavlov. Cond. intertrial magazine entries0.40.71.21.11.00.71.00.8-0.90.80.0-0.6-0.6
Pavlov. Cond. lever-magazine prob. diff.0.10.10.3-0.3-0.5-0.1-0.4-0.20.10.10.40.30.5
Pavlov. Cond. response bias0.10.10.2-0.1-0.30.0-0.20.00.10.10.40.30.5
Time in closed arm before self-admin0.50.61.1-0.7-1.0-1.0-1.0-0.40.7-0.4-0.8-0.7-0.8
Time in closed arm after self-admin0.30.30.80.60.40.60.60.7-0.70.90.4-0.2-0.1
Time in open arm before self-admin0.50.50.90.60.90.90.90.6-0.70.40.80.60.7
Time in open arm after self-admin0.60.72.60.30.70.50.40.20.3-1.10.41.61.3
Bone: periosteal estimation0.00.00.0-0.10.10.0-0.1-0.1-0.10.20.0-0.2-0.2
Bone: periosteal perimeter0.71.31.81.31.31.31.21.3-1.31.01.10.50.6
Bone: post-yield work0.10.10.3-0.2-0.1-0.1-0.0-0.10.3-0.40.10.50.5
Progressive ratio test 1 active lever presses0.10.20.50.40.2-0.00.00.60.2-0.70.00.70.5
Progressive ratio test 1 breakpoint0.20.20.50.40.20.00.00.60.3-0.70.00.70.5
Progressive ratio test 1 inactive lever presses0.50.71.70.90.80.50.71.0-1.11.30.6-0.5-0.2
Progressive ratio test 2 active lever presses1.51.72.71.71.61.41.31.6-1.51.11.20.50.7
Progressive ratio test 2 breakpoint1.51.72.81.71.61.41.31.6-1.51.21.20.50.7
Progressive ratio test 2 inactive lever presses2.03.36.62.02.01.61.72.2-2.42.61.6-0.50.1
Incentive Sensitization - Responses1.62.23.71.71.71.61.61.5-1.91.81.40.10.5
Incentive Sensitization - Breakpoint1.82.33.81.71.71.61.61.5-2.01.91.40.00.4
Sum of active levers in priming session hrs 5-60.40.41.6-0.1-0.2-0.3-0.3-0.20.7-1.3-0.20.90.6
Progressive ratio2.33.65.4-2.3-2.0-2.0-2.2-2.02.2-2.0-1.9-0.6-0.9
Food seeking constrained by brief footshock1.11.42.31.51.01.41.41.4-1.11.01.20.70.8
Seeking ratio, punishment vs. effort4.15.98.83.02.52.82.82.5-2.82.52.40.81.3
Retroperitoneal fat weight1.04.36.3-2.5-2.5-2.4-2.4-2.12.2-1.2-1.9-1.4-1.5
Reaction time number correct0.40.71.31.11.11.00.91.1-0.90.90.5-0.0-0.0
Reaction time mean minus median0.10.20.3-0.5-0.6-0.4-0.4-0.60.4-0.50.10.50.5
Reaction time mean minus median AUC0.20.40.8-0.6-0.7-0.6-0.6-0.80.7-0.9-0.20.50.4
Reaction time num false alarms0.10.20.40.60.60.50.50.5-0.40.10.10.10.0
Reaction time num false alarms AUC0.00.00.10.30.30.20.20.2-0.0-0.3-0.20.2-0.0
Reaction time trials correct on left0.40.71.31.11.11.00.91.1-0.90.90.5-0.0-0.0
Reaction time trials on left0.40.81.31.11.11.00.91.1-0.90.90.5-0.0-0.0
Reaction time mean0.00.00.20.10.1-0.0-0.10.00.2-0.4-0.10.30.1
Reaction time mean AUC0.10.10.40.20.20.0-0.00.10.3-0.6-0.10.50.3
Median of all reaction times0.00.10.20.40.40.20.10.30.0-0.3-0.10.20.0
Reaction time omissions0.10.10.40.30.20.10.30.10.1-0.5-0.6-0.1-0.5
Reaction time false alarm rate0.00.00.2-0.1-0.1-0.1-0.1-0.20.2-0.4-0.30.1-0.1
Reaction time premature initiation rate1.92.64.5-1.8-2.0-2.1-2.0-1.41.8-1.3-1.6-0.9-1.0
Reaction time premature initiations0.61.12.0-1.1-1.3-1.4-1.4-0.61.1-0.7-1.1-0.8-0.9
Std. dev. reaction times0.20.31.1-0.3-0.5-0.4-0.5-0.50.7-1.1-0.30.60.3
Reaction time trials completed0.40.81.31.11.11.00.91.1-0.90.90.5-0.0-0.0
Reaction time trials AUC0.51.01.61.31.31.21.11.3-1.10.90.60.00.0
Run reversals in cocaine runway, females1.81.82.71.61.11.61.51.4-1.41.61.30.30.6
Run reversals in cocaine runway, males1.41.42.9-1.3-1.1-1.3-1.2-0.90.60.1-1.2-1.7-1.5
Latency to leave start box in cocaine runway0.30.30.5-0.7-0.6-0.6-0.7-0.70.4-0.1-0.5-0.6-0.6
Latency to leave start box in cocaine runway, F0.91.12.9-1.0-1.0-1.0-1.0-0.90.30.7-0.8-1.7-1.5
Latency to leave start box in cocaine runway, M0.50.41.20.50.60.60.50.5-0.2-0.40.61.11.0
Std. dev. time between licks in bursts4.15.69.02.62.62.62.62.5-3.03.02.20.10.7
Total sessions with >9 infusions0.60.71.51.00.90.70.81.0-1.11.20.7-0.3-0.0
Short access day 1 total inactive lever presses4.05.27.52.72.52.62.62.5-2.41.92.31.21.5
Short access day 10 total inactive lever presses0.40.93.5-0.7-0.6-0.5-0.5-0.6-0.51.4-0.4-1.9-1.4
Short access day 1 total infusions2.73.55.62.42.22.02.02.3-1.91.21.81.21.4
Short access day 10 total infusions2.22.85.12.21.91.71.82.2-1.50.91.61.21.3
Short access total infusions3.44.37.02.62.32.22.22.6-1.91.11.91.51.6
Short access day 1 locomotion0.40.50.80.90.80.70.70.7-0.80.70.70.30.4
Short access day 10 total locomotion0.10.10.40.30.0-0.1-0.00.50.3-0.6-0.10.50.3
Short access total locomotion0.10.10.40.40.20.10.10.40.1-0.50.10.70.5
One hour access (0.3 mA shock)1.01.12.41.41.21.01.01.6-0.70.10.81.11.0
Compulsive drug intake1.11.43.01.10.91.51.30.8-0.5-0.21.11.71.5
One hour access (shock baseline)0.30.41.10.80.90.30.41.0-0.80.80.4-0.3-0.1
Social response proportion0.40.40.9-0.5-0.6-0.7-0.4-0.40.5-0.2-0.9-0.8-1.0
Social responses0.40.60.8-0.8-0.8-0.9-0.8-0.90.8-0.9-0.7-0.1-0.3
Social time0.50.72.30.60.70.80.70.9-1.21.50.8-0.5-0.1
Soleus weight3.08.814.6-3.8-3.6-3.5-3.4-3.42.9-1.8-2.5-1.8-1.8
Bone: stiffness0.10.20.4-0.6-0.5-0.6-0.6-0.50.4-0.3-0.4-0.3-0.3
Tibialis anterior weight0.00.10.5-0.3-0.2-0.10.0-0.1-0.30.70.1-0.7-0.4
Time to tail flick, vehicle, before self-admin1.21.21.8-1.3-1.0-1.4-1.2-1.01.2-0.8-1.3-0.9-1.0
Time to tail flick, vehicle, after self-admin0.40.51.2-0.7-0.7-0.9-0.9-0.50.20.2-0.7-1.1-0.9
Time to tail flick, test, before self-admin0.50.51.8-0.2-0.3-0.2-0.3-0.10.8-1.4-0.11.10.8
Time to tail flick, test, after self-admin0.10.10.30.40.40.30.30.4-0.50.60.3-0.2-0.1
Delta time to tail flick, vehicle, before/after SA0.20.20.50.50.30.30.20.3-0.70.70.4-0.20.0
Delta time to tail flick, test, before/after SA0.30.30.70.60.70.40.50.5-0.80.80.4-0.3-0.1
Tibia length4.512.521.7-4.7-4.6-4.2-4.3-4.03.8-2.5-2.5-1.2-1.2
Ambulatory time before self-admin0.91.32.61.31.11.21.21.4-1.51.61.0-0.20.1
Ambulatory time after self-admin0.10.10.10.40.20.30.20.3-0.20.10.30.20.3
Bone: tissue strength2.32.33.6-1.9-1.7-1.7-1.7-1.71.1-0.2-1.4-1.7-1.6
Total heroin consumption1.61.83.2-1.6-1.7-1.4-1.5-1.40.70.2-1.1-1.8-1.5
Bone: trabecular number0.81.43.21.31.01.11.41.1-0.3-0.60.81.81.5
Bone: trabecular spacing1.72.24.4-1.7-1.4-1.5-1.7-1.50.60.5-1.2-2.1-1.8
Bone: trabecular thickness0.50.62.0-0.1-0.3-0.2-0.0-0.00.8-1.30.11.41.1
Bone: trabecular tissue density0.40.50.8-0.9-0.9-0.9-0.9-0.80.8-0.7-0.6-0.1-0.2
Water consumed over 24 hours0.20.31.0-0.3-0.3-0.2-0.3-0.2-0.31.0-0.0-1.0-0.7
Number of responses in last shaping day0.60.62.40.40.60.40.40.5-1.11.60.4-1.0-0.6