Hub : Genes

Dzank1

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Brain gene expression Dzank1 0.07 0.04 3.3e-06 0.06 0.05 0.06 0.03 2.0e-06 1.8e-05 2.4e-06 8.0e-04
2 Adipose gene expression Dzank1 0.1 0.07 3.1e-06 0.04 0.04 0.02 0.03 6.8e-05 3.6e-05 1.7e-03 1.3e-04
3 Brain isoform ratio XM_039106611.1 0.03 0.02 7.8e-03 -0 0.01 0 -0 5.1e-01 3.1e-02 1.5e-01 6.0e-01
4 Brain intron excision ratio chr3_131906549_131908083 0.04 0.03 7.6e-03 0.01 0.02 0.01 0.01 4.3e-02 5.0e-03 6.2e-02 3.8e-02
5 Adipose mRNA stability Dzank1 0.03 0.02 4.5e-03 0 -0 -0 -0 1.6e-01 4.1e-01 4.0e-01 5.8e-01
6 PL intron excision ratio chr3_131906549_131907051 0.1 0.06 2.5e-09 0.09 0.07 0.09 0.09 1.9e-10 6.5e-08 1.3e-09 5.3e-10
7 BLA isoform ratio XM_017592225.2 0.12 0.1 4.0e-03 0.02 0 0 0 2.2e-02 2.3e-01 2.9e-01 1.9e-01
8 Brain isoform ratio XM_039106614.1 0.03 0.02 1.0e-02 0.03 0.01 0.03 0.01 1.4e-03 1.3e-02 2.2e-03 2.0e-02
9 PL mRNA stability Dzank1 0.03 0.02 1.4e-03 0.04 0.02 0.01 0.03 2.6e-05 4.0e-03 1.2e-02 2.9e-04
10 Brain mRNA stability Dzank1 0.06 0.03 2.2e-05 0.05 0.06 0.06 0.05 4.3e-05 3.7e-06 7.6e-06 1.6e-05
11 Brain intron excision ratio chr3_131904146_131906433 0.18 0.14 4.2e-03 0 0.02 0.01 0.01 1.0e-01 7.6e-03 1.4e-02 4.2e-02

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11
Bone: apparent density0.10.20.8-0.40.5-0.3-0.50.2-0.2-0.40.00.9-0.10.1
Area under the delay curve1.92.04.4-1.31.8-2.0-0.9-0.40.4-0.4-2.10.91.81.8
BMI with tail5.216.929.35.2-4.53.95.1-5.35.44.90.4-3.60.61.3
BMI without tail4.38.814.43.8-3.73.63.6-3.43.53.11.2-2.7-0.7-0.1
Body weight6.025.245.76.8-6.05.66.0-6.36.35.71.9-3.4-0.70.4
Weight adjusted by age0.30.31.20.2-0.30.5-0.20.0-0.1-0.20.91.1-1.0-0.5
Bone surface0.30.61.10.6-1.11.00.9-0.40.40.50.9-0.9-0.4-0.9
Bone volume0.20.31.10.3-0.60.70.2-0.00.0-0.01.10.2-0.8-0.9
Breakpoint value in progressive ratio session0.50.61.40.7-1.11.00.9-0.40.50.50.6-1.2-0.4-0.6
Number of licking bursts0.40.52.20.00.7-0.6-0.3-0.50.50.4-0.90.70.61.5
Context. condit. distance diff. score0.00.00.20.2-0.20.4-0.00.00.00.10.00.4-0.40.1
Locomotion velocity, session 11.21.34.1-1.3-0.00.0-0.61.3-1.4-1.51.2-0.5-0.8-2.0
Locomotion distance, session 12.63.46.2-2.51.9-1.9-2.12.3-2.3-2.30.21.4-0.1-1.2
Locomotion velocity, session 21.31.53.4-1.81.5-1.8-1.21.1-1.2-1.4-0.50.10.9-0.6
Locomotion distance, session 23.65.19.2-2.71.7-1.3-2.62.8-2.9-3.01.02.2-1.4-1.8
Locomotion velocity, session 32.32.64.7-2.21.9-1.8-2.02.1-2.0-1.9-0.51.10.1-0.2
Locomotion distance, session 31.11.22.2-1.41.5-1.4-1.21.2-1.2-1.0-0.80.80.50.3
Stereotopy head waving bouts, day 30.20.20.60.4-0.60.50.30.2-0.1-0.10.7-0.5-0.5-0.6
Stereotopy head waving duration, day 30.30.30.70.5-0.80.70.5-0.10.20.20.7-0.9-0.4-0.5
Locomotion velocity, session 71.01.12.2-1.00.5-0.4-1.01.2-1.2-1.11.11.3-0.8-1.5
Locomotion distance, session 70.70.82.7-0.2-0.30.4-0.40.7-0.6-0.61.51.1-1.2-1.6
Stereotopy head waving bouts, day 70.10.10.10.4-0.30.40.3-0.20.20.20.2-0.2-0.2-0.1
Stereotopy head waving duration, day 70.10.20.3-0.50.5-0.5-0.40.4-0.3-0.3-0.50.00.40.4
Locomotion velocity, session 81.01.23.4-1.00.00.1-0.71.3-1.3-1.51.10.3-1.1-1.8
Locomotion distance, session 81.92.74.7-1.81.2-0.9-1.92.0-2.1-2.20.91.9-1.2-1.4
Degree of sensitization distance1.51.64.31.0-1.61.50.8-0.60.60.32.10.3-1.5-1.8
Degree of sensitization stereotypy0.20.20.50.5-0.30.30.5-0.60.70.6-0.3-0.30.30.5
Conditioned locomotion0.70.82.3-0.6-0.30.6-0.40.8-0.8-0.91.20.3-1.3-1.5
Cocaine response after cond. corrected1.41.63.5-1.00.9-0.6-1.51.5-1.5-1.40.91.9-1.1-1.0
Cocaine response after cond. not corrected2.42.77.0-1.51.4-1.0-2.11.9-1.9-1.70.92.6-1.2-0.9
Cocaine response before conditioning0.20.20.7-0.70.7-0.6-0.60.2-0.3-0.3-0.10.90.10.3
Saline control response2.53.28.31.4-2.32.61.0-0.40.4-0.02.9-0.1-2.5-2.4
Bone: connectivity density0.10.20.6-0.80.5-0.5-0.50.5-0.5-0.6-0.10.30.2-0.2
Bone: cortical apparent density0.50.71.9-0.50.9-1.1-0.2-0.20.00.2-1.30.01.41.2
Bone: cortical area0.30.40.90.6-0.50.20.7-1.01.00.60.1-0.70.50.2
Bone: cortical porosity0.50.62.40.6-0.70.50.8-0.80.70.7-0.3-1.50.30.5
Bone: cortical porosity0.70.82.40.9-0.90.71.0-1.11.00.9-0.2-1.50.30.5
Bone: cortical thickness0.71.13.10.10.2-0.60.7-1.21.00.8-1.3-1.41.71.4
Bone: cortical thickness0.91.02.8-1.41.5-1.7-1.00.3-0.4-0.7-0.90.71.10.7
Bone: cortical tissue density0.40.51.4-0.40.7-1.0-0.2-0.1-0.00.2-1.00.01.21.0
Condit. Reinf. active minus inactive responses0.20.20.8-0.00.6-0.3-0.60.2-0.1-0.2-0.40.9-0.20.8
Condit. Reinf. active-inactive response ratio0.30.31.2-0.20.7-0.4-0.70.2-0.1-0.3-0.51.1-0.10.8
Condit. Reinf. active responses0.20.20.7-0.20.7-0.4-0.60.3-0.2-0.3-0.40.8-0.00.6
Condit. Reinf. inactive responses0.10.10.60.0-0.40.20.20.1-0.1-0.00.7-0.4-0.2-0.8
Incentive salience index mean0.91.12.2-0.71.5-1.4-0.90.3-0.3-0.4-1.40.91.01.4
Condit. Reinf. lever presses1.41.95.0-0.61.7-1.9-0.5-0.40.40.3-2.20.32.12.0
Condit. Reinf. active minus inactive responses1.41.83.71.3-1.91.91.4-0.80.80.91.6-1.0-1.1-1.3
Condit. Reinf. active-inactive response ratio1.01.12.31.2-1.41.51.2-0.80.81.10.9-0.8-0.7-0.5
Condit. Reinf. active responses0.60.91.71.0-1.20.91.3-0.90.91.00.3-1.30.1-0.2
Condit. Reinf. inactive responses0.40.51.70.10.1-0.50.5-0.50.50.4-1.0-1.01.30.7
Condit. Reinf. lever presses2.43.35.82.3-2.42.42.2-1.81.91.90.8-1.9-0.6-0.2
Condit. Reinf. lever reinforcers received0.81.22.31.2-1.41.21.5-1.01.01.10.4-1.5-0.0-0.3
Conditioned reinforcement - actives1.31.32.7-0.70.10.2-1.01.1-1.1-1.41.50.9-1.5-1.6
Conditioned reinforcement - inactives2.12.44.2-0.80.20.1-1.41.8-1.9-1.81.91.4-2.0-1.9
Conditioned locomotion0.40.41.1-1.00.8-0.8-0.70.6-0.8-0.8-0.50.00.30.2
Patch foraging indifference point 0 sec1.52.46.2-0.1-0.81.1-0.61.4-1.4-1.02.51.3-2.5-2.3
Patch foraging indifference point AUC0.60.61.2-1.01.1-1.1-0.80.6-0.6-0.7-1.00.10.70.6
Delay disc. indifference point, 0s delay0.90.92.00.30.2-0.50.6-1.21.20.8-1.3-0.81.41.3
Delay disc. indifference point, 16s delay2.02.04.3-1.72.1-2.1-1.50.6-0.6-1.1-1.51.31.21.1
Delay disc. indifference point, 2s delay1.41.53.40.30.4-0.60.5-1.71.71.0-1.7-0.01.61.8
Delay disc. indifference point, 24s delay4.44.29.0-2.53.0-3.0-2.41.4-1.3-1.7-1.72.11.41.1
Delay disc. indifference point, 4s delay0.90.92.20.10.5-0.60.2-1.51.50.6-1.20.41.21.3
Delay disc. indifference point, 8s delay1.71.73.4-1.81.8-1.8-1.30.5-0.4-1.1-1.60.81.21.0
Indifference point function ln k0.60.92.8-0.0-0.70.7-0.20.6-0.4-0.51.70.6-1.4-1.6
Indifference point function log k0.60.92.8-0.0-0.70.7-0.20.6-0.4-0.51.70.6-1.4-1.6
Patch foraging total patch changes 0 sec1.32.25.3-0.4-0.50.9-0.71.5-1.6-1.12.21.3-2.3-2.1
Patch foraging total patch changes 12 sec0.20.20.40.5-0.70.50.6-0.60.50.40.50.0-0.1-0.5
Patch foraging total patch changes 18 sec1.01.32.4-0.90.6-0.3-1.31.5-1.6-1.30.81.4-1.2-0.9
Patch foraging total patch changes 24 sec0.10.10.3-0.20.10.0-0.40.4-0.5-0.30.30.5-0.5-0.2
Patch foraging total patch changes 6 sec0.40.52.0-0.20.20.2-0.60.8-0.9-0.40.81.4-1.0-0.5
Patch foraging time to switch 0 sec1.32.14.11.9-1.30.91.7-2.01.81.9-0.2-1.30.80.9
Patch foraging water rate 0 sec1.72.84.5-2.11.9-1.5-2.12.1-2.0-2.1-0.41.6-0.3-0.3
Patch foraging water rate 12 sec2.84.38.1-2.52.8-2.7-2.52.0-1.9-1.9-1.22.30.80.6
Patch foraging water rate 18 sec6.89.214.7-3.63.2-2.8-3.83.4-3.5-3.80.43.8-0.8-1.4
Patch foraging water rate 24 sec2.94.07.1-2.31.8-1.3-2.52.5-2.3-2.70.62.5-1.2-1.1
Patch foraging water rate 6 sec3.24.77.8-2.62.5-2.2-2.82.7-2.5-2.7-0.32.2-0.2-0.4
Seeking ratio, delayed vs. immediate footshock0.40.51.00.8-1.00.80.7-0.10.20.50.8-1.0-0.5-0.6
Distance traveled before self-admin0.20.20.40.5-0.2-0.00.5-0.60.60.6-0.2-0.40.60.2
Distance traveled after self-admin0.91.03.4-0.60.9-1.0-0.10.0-0.00.2-1.8-1.01.51.6
Extensor digitorum longus weight0.20.71.31.0-1.11.10.7-0.50.50.51.0-0.3-0.8-0.8
Bone: elastic displacement0.50.62.50.4-0.60.21.0-0.80.60.8-0.4-1.60.8-0.2
Bone: elastic work2.22.95.31.8-1.51.02.1-2.32.22.1-0.4-2.11.10.7
Bone: endosteal estimation1.73.67.52.4-2.52.71.7-1.41.61.32.3-0.1-2.0-1.4
Bone: endosteal perimeter0.81.74.51.1-1.51.80.5-0.10.3-0.02.10.4-2.0-1.7
Epididymis fat weight4.29.816.74.1-3.83.63.8-3.73.93.71.3-1.9-0.5-0.1
Delta time in closed arm before/after self-admin0.30.30.9-0.40.3-0.0-0.50.9-0.9-0.50.40.4-0.6-0.5
Delta time in open arm before/after self-admin1.11.11.81.3-1.11.11.2-1.21.31.30.1-0.90.00.5
Diff in mean of infusions in LGA sessions0.40.41.1-0.40.9-1.0-0.40.2-0.2-0.0-0.90.10.90.7
Delay discount exponential model param2.02.14.31.4-1.92.11.00.2-0.30.52.0-1.1-1.8-1.7
Extinction: sum of active levers before priming0.30.31.0-0.1-0.20.3-0.30.6-0.6-0.40.90.2-0.8-1.0
Active lever presses in extinction session 62.12.04.31.3-2.12.01.3-0.60.60.51.9-0.9-1.5-1.8
Bone: final force0.40.71.91.0-0.60.50.9-1.31.40.90.1-0.30.30.6
Bone: final moment0.40.61.50.9-0.60.50.8-1.21.20.90.2-0.20.20.5
Food consumed during 24 hour testing period0.10.20.50.5-0.20.10.2-0.70.70.20.30.6-0.00.0
Glucose1.01.53.41.1-1.71.70.9-0.50.50.31.80.0-1.4-1.5
Heart weight1.72.54.11.9-2.02.01.8-1.91.91.80.9-0.8-0.6-0.1
Delay discount hyperbolic model param1.71.83.91.1-1.71.80.80.6-0.60.22.0-0.9-1.8-1.7
Intermittent access intake day 1-15 change1.51.53.41.2-1.71.70.9-0.50.30.41.8-0.5-1.4-1.4
Intermittent access intake escalation1.11.02.90.9-1.31.40.6-0.30.10.11.7-0.1-1.4-1.3
Intermittent access intake escalation 21.31.33.01.2-1.51.60.8-0.50.50.41.70.0-1.4-1.1
Intermitt. access day 1 inactive lever presses0.10.10.7-0.00.2-0.2-0.30.3-0.3-0.20.40.8-0.3-0.2
Intermitt. access day 15 inactive lever presses2.42.67.91.4-1.92.00.70.2-0.30.12.80.4-2.3-2.4
Intermitt. access escalation Index2.11.94.41.4-2.02.11.5-0.70.70.91.1-1.7-1.0-0.9
Intermittent access day 1 total infusions0.20.21.00.1-0.50.20.5-0.50.50.10.1-1.00.3-0.6
Intermittent access day 15 total infusions1.11.22.50.9-1.61.31.0-0.70.50.21.6-0.8-0.9-1.6
Intermittent access terminal intake (last 3 days)1.11.22.61.0-1.61.21.2-0.80.70.41.3-1.0-0.6-1.5
Intermittent access total infusions0.80.92.00.8-1.41.21.0-0.60.60.31.1-1.0-0.6-1.2
Intermittent access day 1 locomotion0.60.61.9-0.30.2-0.60.4-0.70.60.2-1.1-1.31.40.6
Intermittent access day 15 total locomotion0.10.10.20.2-0.40.40.3-0.30.30.10.2-0.4-0.1-0.2
Intermittent access total locomotion0.20.20.8-0.40.2-0.50.1-0.30.3-0.0-0.7-0.60.90.3
Intermittent access standard deviation0.50.51.4-0.2-0.30.4-0.30.6-0.6-0.71.20.5-1.0-1.1
Left kidney weight1.13.05.22.3-2.22.12.0-2.22.01.90.9-1.1-0.5-0.0
Right kidney weight1.02.95.92.4-2.22.11.9-1.91.81.91.0-0.8-0.7-0.1
Cocaine induced anxiety0.50.61.9-0.5-0.30.3-0.40.7-0.7-1.01.10.4-1.0-1.4
Post-drug Anxiety1.51.63.31.6-1.81.81.2-0.80.80.81.6-0.2-1.2-1.2
Baseline Anxiety1.92.04.32.1-1.81.91.7-1.31.41.70.8-1.0-0.6-0.1
Tail length0.61.94.11.5-1.82.01.0-0.50.50.52.0-0.2-1.8-1.6
Length with tail1.24.58.92.7-2.93.02.2-2.12.01.72.1-0.7-1.7-1.2
Length without tail0.92.04.11.9-1.71.51.6-2.01.91.50.6-0.6-0.20.2
Times rat made contact with spout2.63.05.12.0-2.22.12.2-1.91.91.80.9-1.7-0.4-0.5
Lifetime Intake0.50.61.20.6-1.11.10.7-0.20.20.11.0-0.7-0.8-1.1
Liver weight, left0.00.00.10.3-0.30.20.2-0.1-0.00.20.3-0.1-0.1-0.3
Liver weight, right0.00.00.10.2-0.0-0.20.1-0.40.30.10.20.20.2-0.2
Locomotor activity0.10.20.40.4-0.60.50.5-0.60.60.4-0.1-0.5-0.00.1
Locomotor testing distance0.10.10.3-0.50.2-0.2-0.30.4-0.3-0.5-0.20.0-0.0-0.1
Locomotor testing rearing0.00.10.20.2-0.20.40.2-0.20.20.2-0.2-0.1-0.10.4
Locomotion in novel chamber1.21.42.6-1.00.30.2-1.21.5-1.6-1.51.10.9-1.6-1.3
Locomotion in novel chamber post-restriction1.41.73.1-1.81.5-1.1-1.81.4-1.5-1.7-0.41.4-0.40.0
Fecal boli incidents, locomotor time 11.41.53.9-1.10.6-0.3-1.41.2-1.2-1.61.02.0-1.3-1.2
Change in fecal boli incidents, locomotor task0.10.10.5-0.1-0.10.10.20.3-0.30.1-0.4-0.70.2-0.0
Time >=10cm from walls, locomotor time 10.30.31.0-0.60.5-0.3-0.60.5-0.5-0.50.01.0-0.3-0.2
Bouts of movement, locomotor time 11.31.42.9-1.21.2-1.0-1.61.2-1.3-1.40.41.7-0.6-0.5
Total resting periods, locomotor time 11.82.03.6-1.41.3-1.1-1.81.6-1.7-1.70.71.9-0.8-0.9
Rest time, locomotor task time 10.70.81.7-0.40.6-0.3-1.11.1-1.1-0.80.91.3-1.0-0.6
Distance moved, locomotor task time 11.51.75.2-1.21.4-1.9-0.3-0.10.2-0.3-2.1-0.32.31.3
Vertical activity count, locomotor time 10.70.71.70.5-0.20.00.8-1.31.30.9-0.8-0.31.00.9
Time >=10cm from walls, locomotor time 21.21.32.11.4-1.41.41.4-1.31.31.20.6-0.8-0.3-0.1
Bouts of movement, locomotor time 20.30.31.30.3-0.50.20.6-0.80.80.2-0.2-1.10.40.2
Total resting periods, locomotor time 20.30.30.90.3-0.60.40.6-0.80.70.20.1-1.00.2-0.1
Rest time, locomotor task time 20.10.20.6-0.1-0.20.1-0.20.3-0.3-0.20.70.4-0.5-0.8
Distance moved, locomotor task time 20.80.92.2-0.91.3-1.5-0.80.5-0.5-0.7-1.20.21.10.9
Vertical activity count, locomotor time 20.40.41.5-0.10.6-0.6-0.0-0.40.40.2-1.1-0.30.91.2
Light reinforcement 10.40.82.5-0.1-0.20.6-0.60.4-0.4-1.01.21.3-1.6-1.1
Light reinforcement 21.11.54.5-0.1-1.01.4-0.20.7-0.8-1.21.7-0.3-2.1-1.9
Bone: marrow area1.73.77.72.4-2.62.81.7-1.31.51.22.4-0.1-2.0-1.5
Bone: maximum diameter0.81.53.01.6-1.61.61.0-0.91.00.71.7-0.1-1.2-1.0
Bone: maximum force0.30.51.21.0-0.60.50.6-1.11.10.60.40.1-0.10.5
Bone: maximum moment0.20.41.10.9-0.50.40.6-1.11.00.70.30.10.00.5
Mean time between licks in bursts0.30.40.6-0.70.8-0.5-0.80.6-0.6-0.7-0.40.6-0.00.5
Mean num. licks in bursts1.61.93.91.1-2.01.71.5-0.60.60.61.6-1.5-0.8-2.0
Cd content in liver0.60.72.10.80.3-0.10.3-1.01.01.1-0.50.80.61.4
Co content in liver0.60.71.6-1.21.2-1.3-0.80.4-0.6-0.5-0.90.70.80.3
Cu content in liver0.30.40.7-0.50.4-0.4-0.70.7-0.7-0.80.50.8-0.4-0.6
Fe content in liver0.30.30.60.8-0.70.70.6-0.70.60.60.4-0.1-0.20.3
K content in liver2.42.45.7-1.72.0-2.4-1.00.4-0.4-0.5-2.1-0.22.31.5
Mg content in liver0.80.82.4-0.70.9-1.1-0.1-0.20.10.2-1.4-0.71.51.4
Mn content in liver1.41.53.3-1.70.7-0.4-1.31.8-1.7-1.70.70.4-0.9-1.2
Na content in liver1.71.85.2-0.30.6-1.10.5-0.80.70.8-2.1-1.72.31.9
Rb content in liver0.70.82.6-0.01.0-1.1-0.3-0.60.40.4-1.20.91.11.6
Se content in liver0.30.41.4-0.10.4-0.60.3-0.60.50.6-0.6-0.21.20.7
Sr content in liver0.50.40.8-0.60.3-0.2-0.70.7-0.7-0.90.50.8-0.7-0.6
Zn content in liver0.20.20.5-0.40.6-0.6-0.3-0.1-0.0-0.1-0.70.30.60.7
Bone: minimum diameter0.51.01.81.2-1.41.21.2-1.01.10.70.9-0.9-0.4-0.4
Time in familiar zone, hab. session 10.70.71.90.40.4-0.60.4-0.60.50.9-1.1-0.31.41.3
Time in novel zone, hab. session 10.50.51.70.2-0.91.10.1-0.00.1-0.31.00.1-1.3-0.9
Total zone transitions, hab. session 10.60.81.5-1.20.9-1.0-0.91.1-1.2-1.10.30.20.1-0.8
Total locomotion distance, hab. session 11.11.52.8-1.61.2-1.3-1.31.7-1.5-1.60.40.50.0-0.9
Locomotion velocity, hab. session 11.41.93.4-1.81.5-1.6-1.61.9-1.7-1.8-0.00.70.2-0.7
Time in familiar zone, hab. session 20.20.20.5-0.30.10.1-0.40.7-0.7-0.50.10.1-0.5-0.2
Time in novel zone, hab. session 20.60.61.01.0-0.90.90.9-1.01.00.70.6-0.4-0.2-0.3
Total zone transitions, hab. session 20.30.41.3-0.2-0.40.6-0.20.4-0.4-0.51.00.3-1.1-1.1
Total locomotion distance, hab. session 21.21.63.7-0.8-0.30.6-0.81.3-1.4-1.41.70.8-1.9-1.9
Locomotion velocity, hab. session 21.31.83.1-1.20.20.1-1.21.6-1.7-1.71.30.9-1.6-1.8
Novel to familiar place preference ratio0.10.10.40.40.10.1-0.1-0.20.20.40.10.5-0.20.6
Novelty place preference0.20.20.90.40.2-0.0-0.1-0.30.20.4-0.20.40.01.0
Time in novel zone, NPP test0.30.30.80.8-0.20.40.2-0.60.50.70.00.3-0.20.9
Total zone transitions, NPP test0.40.61.0-1.00.7-0.6-0.90.9-0.9-1.00.40.6-0.3-0.7
Total locomotion distance, NPP test1.42.03.4-1.40.6-0.3-1.41.7-1.7-1.91.31.3-1.4-1.6
Locomotion velocity, NPP test1.62.34.0-1.71.0-0.7-1.71.9-1.9-2.01.01.4-1.1-1.5
Intraocular pressure1.72.45.7-1.31.0-0.5-1.81.9-1.7-1.71.22.4-1.6-1.4
Delta distance traveled before/after self-admin1.41.55.5-0.61.1-1.0-0.1-0.10.10.4-2.3-0.71.62.2
Delta ambulatory time before/after self-admin0.80.93.4-0.71.0-0.8-0.40.1-0.10.1-1.9-0.41.11.8
Parametrial fat weight9.819.031.25.4-5.55.05.6-5.15.04.51.6-4.6-0.3-0.6
Pavlov. Cond. lever latency2.83.68.21.6-2.72.91.4-0.40.40.42.7-1.2-2.5-2.1
Pavlov. Cond. magazine entry latency0.81.13.5-0.20.9-1.00.0-0.60.40.4-1.9-0.31.71.7
Pavlov. Cond. change in total contacts4.34.610.0-1.63.0-3.1-1.50.3-0.4-0.4-3.21.52.72.7
Pavlov. Cond. index score2.53.28.6-1.02.2-2.4-0.7-0.30.20.2-2.90.42.82.5
Pavlov. Cond. latency score2.93.89.1-1.52.6-2.8-1.20.1-0.2-0.2-3.00.82.72.5
Pavlov. Cond. lever contacts1.82.25.2-0.91.9-2.2-0.7-0.20.10.1-2.20.82.31.7
Pavlov. Cond. magazine entry number1.01.33.4-0.1-0.71.0-0.31.0-0.9-0.81.80.2-1.9-1.8
Pavlov. Cond. intertrial magazine entries2.53.08.2-0.4-0.61.2-1.02.0-1.8-1.72.50.9-2.9-2.3
Pavlov. Cond. lever-magazine prob. diff.2.83.59.8-0.92.1-2.5-0.6-0.40.30.4-3.10.33.02.7
Pavlov. Cond. response bias1.61.95.1-0.31.4-1.7-0.1-0.80.70.7-2.30.32.32.1
Pavlov. Cond. lever latency3.64.98.9-3.02.6-2.4-2.72.7-2.7-2.7-0.71.60.2-0.2
Pavlov. Cond. magazine entry latency2.93.37.52.1-2.52.71.5-1.01.00.92.3-0.5-2.1-1.7
Pavlov. Cond. change in total contacts4.05.59.23.0-2.82.53.0-2.72.82.80.4-2.30.10.2
Pavlov. Cond. index score4.25.410.03.2-3.02.92.8-2.52.62.51.2-1.6-0.8-0.3
Pavlov. Cond. latency score3.23.97.42.7-2.52.42.4-2.22.22.21.0-1.4-0.6-0.2
Pavlov. Cond. lever contacts3.14.27.92.8-2.42.22.5-2.62.52.50.7-1.4-0.20.3
Pavlov. Cond. magazine entry number3.24.07.7-2.62.8-2.7-2.21.7-1.8-1.7-1.81.21.31.1
Pavlov. Cond. intertrial magazine entries1.52.04.0-1.72.0-1.9-1.50.9-0.9-0.9-1.70.91.11.3
Pavlov. Cond. lever-magazine prob. diff.4.45.610.43.2-2.92.82.9-2.72.72.60.9-1.9-0.5-0.0
Pavlov. Cond. response bias3.64.98.93.0-2.92.92.6-2.32.32.21.5-1.4-1.1-0.7
Time in closed arm before self-admin0.40.41.5-0.1-0.40.3-0.20.6-0.5-0.51.10.1-0.9-1.2
Time in closed arm after self-admin1.41.43.5-0.6-0.10.2-0.81.5-1.5-1.31.50.5-1.4-1.9
Time in open arm before self-admin0.60.61.90.10.1-0.20.6-0.60.50.7-1.4-0.81.21.1
Time in open arm after self-admin2.12.34.91.2-0.90.61.8-1.71.71.8-1.4-2.21.51.5
Bone: periosteal estimation1.02.13.91.8-2.01.91.5-1.31.41.01.7-0.5-1.1-1.0
Bone: periosteal perimeter0.40.71.80.8-1.11.20.6-0.30.40.11.3-0.4-1.0-1.0
Bone: post-yield work0.10.20.50.4-0.20.3-0.10.1-0.2-0.10.70.7-0.7-0.2
Progressive ratio test 1 active lever presses0.30.31.00.5-0.60.40.7-0.50.40.40.1-1.00.2-0.3
Progressive ratio test 1 breakpoint0.50.51.30.7-0.70.40.9-0.80.70.7-0.0-1.10.4-0.1
Progressive ratio test 1 inactive lever presses0.60.72.30.5-0.70.90.00.3-0.4-0.31.50.4-1.4-1.2
Progressive ratio test 2 active lever presses0.10.10.30.3-0.40.30.3-0.50.40.10.40.0-0.1-0.4
Progressive ratio test 2 breakpoint0.10.10.30.3-0.50.30.4-0.50.40.20.3-0.20.0-0.4
Progressive ratio test 2 inactive lever presses1.41.64.30.8-1.61.70.5-0.30.1-0.22.10.0-1.9-1.7
Incentive Sensitization - Responses0.20.20.50.0-0.40.5-0.00.0-0.2-0.30.60.2-0.7-0.5
Incentive Sensitization - Breakpoint0.20.20.60.2-0.60.70.1-0.0-0.1-0.10.70.0-0.8-0.6
Sum of active levers in priming session hrs 5-61.11.02.0-0.80.4-0.4-1.01.4-1.4-1.20.90.7-0.8-1.3
Progressive ratio1.41.63.4-1.40.9-0.5-1.51.9-1.7-1.50.51.1-1.1-1.0
Food seeking constrained by brief footshock1.61.93.7-1.71.7-1.9-1.01.2-1.2-0.6-1.9-0.61.61.0
Seeking ratio, punishment vs. effort1.82.24.11.0-0.3-0.21.4-1.61.51.6-1.6-2.02.01.7
Retroperitoneal fat weight9.330.652.27.2-6.25.66.9-7.27.06.61.0-4.50.41.1
Reaction time number correct1.52.14.7-1.41.0-0.4-1.91.6-1.5-2.20.72.0-1.6-0.6
Reaction time mean minus median2.02.64.92.2-2.22.12.0-1.41.51.80.9-1.3-0.5-0.5
Reaction time mean minus median AUC1.82.34.82.0-2.12.21.8-1.21.41.51.1-1.0-0.9-0.6
Reaction time num false alarms1.52.04.4-2.11.2-1.3-1.61.5-1.6-2.00.41.2-0.2-1.2
Reaction time num false alarms AUC1.21.74.0-2.01.3-1.3-1.51.4-1.4-1.80.21.1-0.1-0.8
Reaction time trials correct on left1.52.14.7-1.41.0-0.4-1.91.6-1.5-2.20.72.0-1.6-0.6
Reaction time trials on left1.52.14.5-1.40.9-0.3-1.81.6-1.4-2.10.72.0-1.6-0.6
Reaction time mean3.14.48.12.8-2.72.52.6-2.22.32.31.1-1.7-0.5-0.4
Reaction time mean AUC2.73.66.02.5-2.42.22.4-2.02.12.10.9-1.7-0.3-0.5
Median of all reaction times2.73.66.62.6-2.42.22.4-2.12.22.11.0-1.5-0.4-0.3
Reaction time omissions0.50.72.01.3-1.11.40.9-0.60.61.00.4-0.3-0.70.1
Reaction time false alarm rate0.30.41.2-1.10.6-0.9-0.50.6-0.7-0.70.10.10.4-0.7
Reaction time premature initiation rate0.10.20.8-0.1-0.30.2-0.10.1-0.0-0.40.70.3-0.5-0.9
Reaction time premature initiations0.81.12.2-0.90.3-0.1-1.01.0-0.8-1.51.01.3-1.3-1.3
Std. dev. reaction times2.33.26.22.5-2.32.22.2-1.71.92.11.0-1.3-0.5-0.4
Reaction time trials completed1.52.14.5-1.40.9-0.3-1.81.6-1.4-2.10.72.0-1.6-0.6
Reaction time trials AUC1.72.44.9-1.30.8-0.1-1.81.7-1.5-2.21.12.2-2.0-0.9
Run reversals in cocaine runway, females1.71.72.81.4-1.41.41.6-1.71.71.4-0.1-1.30.10.5
Run reversals in cocaine runway, males2.22.24.21.5-0.80.31.7-2.12.01.8-1.1-1.21.61.3
Latency to leave start box in cocaine runway0.80.91.9-0.7-0.30.4-0.51.2-1.1-1.21.0-0.1-1.2-1.4
Latency to leave start box in cocaine runway, F0.80.92.60.2-0.91.00.00.3-0.3-0.61.60.5-1.5-1.5
Latency to leave start box in cocaine runway, M0.80.81.7-1.30.6-0.6-0.51.3-1.1-0.9-0.7-1.30.4-0.2
Std. dev. time between licks in bursts0.81.01.9-1.21.4-1.1-1.20.9-0.9-0.9-0.71.30.20.4
Total sessions with >9 infusions0.60.71.11.0-1.01.01.0-0.90.90.90.1-0.9-0.00.1
Short access day 1 total inactive lever presses2.02.36.3-0.5-0.40.9-1.01.3-1.3-1.52.21.5-2.5-2.0
Short access day 10 total inactive lever presses0.50.51.70.7-0.81.20.3-0.10.20.21.10.3-1.3-0.5
Short access day 1 total infusions0.60.61.4-0.50.00.3-0.70.9-1.0-1.01.00.6-1.2-1.0
Short access day 10 total infusions0.20.20.40.2-0.60.60.4-0.20.3-0.00.5-0.6-0.4-0.6
Short access total infusions0.30.30.80.5-0.80.90.6-0.20.30.30.4-0.9-0.4-0.5
Short access day 1 locomotion0.20.20.60.4-0.60.70.6-0.40.40.4-0.0-0.8-0.10.1
Short access day 10 total locomotion0.40.51.0-0.81.0-1.0-0.80.3-0.2-0.7-0.40.90.40.2
Short access total locomotion0.50.61.7-0.30.4-0.50.2-0.50.50.3-1.3-0.81.21.0
One hour access (0.3 mA shock)0.30.31.0-0.50.2-0.1-0.61.0-0.9-0.70.4-0.2-0.5-0.6
Compulsive drug intake1.31.34.6-0.80.9-0.5-1.32.1-2.1-0.90.20.4-0.8-0.4
One hour access (shock baseline)0.30.31.10.5-0.60.40.7-1.01.10.40.2-0.30.2-0.1
Social response proportion3.33.66.72.1-2.22.02.5-2.12.02.20.1-2.60.20.1
Social responses0.20.20.80.3-0.40.30.5-0.90.90.30.0-0.10.20.0
Social time0.91.23.30.9-0.90.71.2-1.81.71.2-0.5-0.90.60.9
Soleus weight0.00.10.20.5-0.30.40.1-0.20.30.10.30.5-0.5-0.1
Bone: stiffness0.10.20.40.5-0.40.40.1-0.40.5-0.10.60.6-0.50.2
Tibialis anterior weight0.62.24.82.2-1.61.51.7-1.71.82.10.3-0.9-0.10.4
Time to tail flick, vehicle, before self-admin3.53.57.71.7-2.62.71.4-0.20.20.52.8-0.8-2.4-2.5
Time to tail flick, vehicle, after self-admin0.40.42.0-0.40.7-1.0-0.70.2-0.2-0.50.31.40.2-0.5
Time to tail flick, test, before self-admin0.10.10.4-0.10.2-0.3-0.30.5-0.5-0.30.40.3-0.1-0.6
Time to tail flick, test, after self-admin2.42.56.8-0.1-0.71.1-0.71.1-1.2-1.22.51.7-2.6-2.3
Delta time to tail flick, vehicle, before/after SA2.01.94.7-1.32.0-2.1-1.60.5-0.6-1.0-0.92.20.90.8
Delta time to tail flick, test, before/after SA0.90.82.6-0.2-0.40.8-0.40.6-0.6-0.71.31.0-1.6-1.1
Tibia length2.05.79.72.9-2.92.43.1-2.82.92.50.9-2.40.2-0.6
Ambulatory time before self-admin0.30.30.60.7-0.50.30.7-0.80.70.70.1-0.50.40.1
Ambulatory time after self-admin1.01.13.8-0.61.1-1.1-0.20.00.10.2-2.0-0.51.51.8
Bone: tissue strength1.01.01.91.2-0.80.71.2-1.31.31.4-0.3-0.90.50.6
Total heroin consumption1.31.53.9-0.6-0.40.8-0.61.3-1.3-1.21.60.3-1.9-2.0
Bone: trabecular number0.20.40.9-1.00.8-0.7-0.70.5-0.5-0.6-0.30.60.30.1
Bone: trabecular spacing1.21.63.31.8-1.41.01.6-1.51.61.5-0.0-1.10.40.2
Bone: trabecular thickness0.10.10.2-0.50.4-0.4-0.40.1-0.2-0.4-0.10.30.10.1
Bone: trabecular tissue density0.91.33.50.80.0-0.30.8-1.31.31.3-1.4-0.71.41.9
Water consumed over 24 hours0.81.03.10.5-1.11.20.3-0.10.1-0.01.80.3-1.5-1.5
Number of responses in last shaping day0.70.72.0-0.10.10.1-0.70.8-0.9-0.71.31.4-1.2-1.0