Hub : Genes

Dzank1

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Brain gene expression Dzank1 0.06 0.04 1.7e-05 0.05 0.03 0.04 0.03 1.4e-05 4.1e-04 1.2e-04 1.6e-03
2 Adipose gene expression Dzank1 0.1 0.06 6.4e-07 0.04 0.05 0.02 0.04 3.6e-05 6.1e-06 1.1e-03 2.9e-05
3 pVTA intron excision ratio chr3_152359881_152360383 0.06 0.04 1.8e-05 0.05 0.05 0.05 0.05 8.9e-05 1.2e-04 4.8e-05 9.3e-05
4 pVTA intron excision ratio chr3_152359881_152361415 0.05 0.03 1.5e-04 0.05 0.04 0.04 0.04 1.2e-04 2.5e-04 2.6e-04 3.5e-04
5 Adipose mRNA stability Dzank1 0.02 0.02 9.7e-03 0 -0 -0 0 2.8e-01 6.4e-01 8.3e-01 2.4e-01
6 PL intron excision ratio chr3_152359881_152360383 0.1 0.06 6.2e-09 0.07 0.06 0.09 0.09 1.3e-08 9.8e-07 1.1e-09 1.4e-09
7 PL mRNA stability Dzank1 0.03 0.02 3.9e-04 0.05 0.02 0.03 0.04 2.6e-06 1.6e-03 3.5e-04 7.2e-05
8 pVTA gene expression Dzank1 0.15 0.08 4.4e-06 0.02 0.06 0.06 0.05 1.5e-02 1.4e-05 1.7e-05 6.8e-05
9 PL intron excision ratio chr3_152359881_152361415 0.03 0.03 1.4e-03 0.01 0.02 0.03 0.03 2.7e-02 1.0e-03 8.6e-04 8.4e-04
10 Brain mRNA stability Dzank1 0.05 0.03 1.1e-04 0.01 0.02 0 0.01 2.0e-02 3.7e-03 1.2e-01 3.0e-02
11 Brain intron excision ratio chr3_152357478_152359765 0.21 0.16 2.7e-03 0.02 0.01 0.03 0.01 5.1e-03 1.7e-02 8.1e-04 2.9e-02

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11
Bone: apparent density0.10.20.9-0.40.6-0.50.5-0.1-0.31.00.10.30.10.1
Area under the delay curve1.21.95.0-1.42.0-0.50.4-0.30.50.62.21.91.8-1.3
BMI with tail6.221.538.66.2-5.36.0-5.85.75.3-4.4-1.92.11.1-3.3
BMI without tail2.915.727.35.2-4.65.1-4.84.84.5-3.6-1.92.20.7-2.9
Body weight6.327.660.77.8-6.96.6-6.56.45.4-4.1-3.21.4-0.2-3.1
Weight adjusted by age0.20.51.8-0.40.2-0.80.8-0.7-0.81.4-0.4-0.6-0.90.4
Bone surface0.20.41.00.7-1.00.7-0.30.70.3-0.6-0.7-0.1-0.20.7
Bone volume0.10.20.60.3-0.40.00.40.2-0.20.3-0.6-0.3-0.50.8
Breakpoint value in progressive ratio session0.40.72.50.6-1.01.0-0.80.60.5-1.6-1.0-0.0-0.20.3
Number of licking bursts0.10.30.80.10.60.10.00.40.30.30.40.80.6-0.9
Context. condit. distance diff. score0.10.10.50.2-0.10.0-0.20.0-0.20.4-0.7-0.3-0.4-0.2
Locomotion velocity, session 11.61.89.9-1.3-0.0-0.81.6-1.4-1.1-0.6-0.4-0.7-0.93.1
Locomotion distance, session 12.83.66.9-2.51.9-2.22.6-2.2-1.81.31.2-0.7-0.32.5
Locomotion velocity, session 21.61.96.0-1.81.4-1.01.6-1.2-0.50.01.80.60.92.5
Locomotion distance, session 24.36.112.2-2.71.7-2.83.5-3.0-2.81.9-0.1-1.7-1.53.3
Locomotion velocity, session 32.02.24.6-2.11.9-1.82.0-1.7-1.51.10.9-0.20.01.3
Locomotion distance, session 30.70.82.1-1.31.4-1.01.1-0.8-0.70.60.90.30.50.5
Stereotopy head waving bouts, day 30.20.21.00.2-0.50.10.6-0.2-0.2-0.5-0.4-0.6-0.51.0
Stereotopy head waving duration, day 30.20.20.60.4-0.80.30.10.0-0.0-0.7-0.6-0.5-0.50.6
Locomotion velocity, session 71.41.54.7-1.00.6-1.41.4-1.3-1.11.40.3-0.9-0.92.2
Locomotion distance, session 70.70.93.2-0.1-0.3-0.70.8-0.7-0.81.0-0.3-1.2-1.21.8
Stereotopy head waving bouts, day 70.10.10.40.3-0.10.40.10.50.4-0.30.30.60.40.3
Stereotopy head waving duration, day 70.10.10.3-0.50.5-0.20.5-0.2-0.1-0.00.20.50.30.4
Locomotion velocity, session 81.21.45.7-1.0-0.0-0.91.4-1.4-1.20.2-0.5-1.2-1.12.4
Locomotion distance, session 82.13.15.7-1.81.1-2.02.4-2.1-2.01.8-0.1-1.6-1.32.0
Degree of sensitization distance0.91.02.51.1-1.60.3-0.30.20.00.3-1.0-1.3-1.51.4
Degree of sensitization stereotypy0.20.20.60.5-0.30.6-0.20.70.5-0.4-0.20.80.30.0
Conditioned locomotion0.60.71.8-0.3-0.6-0.40.3-0.7-0.90.1-1.3-1.1-1.31.0
Cocaine response after cond. corrected1.42.14.2-1.00.9-1.82.0-1.5-1.62.00.1-1.4-1.21.2
Cocaine response after cond. not corrected2.33.37.3-1.51.4-2.32.5-2.0-2.02.70.2-1.5-1.31.1
Cocaine response before conditioning0.20.20.5-0.60.7-0.40.2-0.4-0.20.60.40.20.1-0.4
Saline control response1.92.67.11.1-2.10.10.4-0.4-0.80.2-2.6-2.3-2.71.5
Bone: connectivity density0.10.20.5-0.70.6-0.50.0-0.3-0.30.40.40.20.4-0.0
Bone: cortical apparent density0.40.61.6-0.70.9-0.2-0.7-0.10.30.01.20.71.2-1.3
Bone: cortical area0.30.41.20.5-0.40.6-0.90.71.1-0.50.60.50.7-0.6
Bone: cortical porosity0.40.51.70.5-0.40.7-0.70.60.9-1.30.00.50.6-0.7
Bone: cortical porosity0.60.61.70.8-0.80.9-0.90.71.0-1.3-0.20.40.4-0.9
Bone: cortical thickness1.11.83.9-0.00.30.8-1.60.91.6-1.21.51.72.0-1.7
Bone: cortical thickness0.70.92.9-1.21.4-0.90.3-0.50.00.81.70.71.1-0.4
Bone: cortical tissue density0.30.51.3-0.60.8-0.3-0.6-0.10.20.11.00.51.0-1.1
Condit. Reinf. active minus inactive responses0.10.10.5-0.00.5-0.30.3-0.1-0.30.7-0.30.2-0.2-0.6
Condit. Reinf. active-inactive response ratio0.20.20.8-0.20.6-0.50.3-0.1-0.30.9-0.20.2-0.2-0.8
Condit. Reinf. active responses0.10.10.4-0.20.6-0.40.4-0.2-0.40.6-0.00.3-0.1-0.1
Condit. Reinf. inactive responses0.10.21.50.1-0.40.10.0-0.1-0.0-0.50.1-0.2-0.21.2
Incentive salience index mean0.50.72.1-0.71.4-0.60.4-0.10.00.71.11.10.9-0.6
Condit. Reinf. lever presses1.21.85.2-0.61.7-0.2-0.00.50.90.42.32.02.1-1.0
Condit. Reinf. active minus inactive responses0.91.44.01.5-2.01.2-1.20.70.8-1.2-1.5-0.5-1.00.4
Condit. Reinf. active-inactive response ratio0.50.82.01.2-1.41.1-0.80.80.7-1.0-1.3-0.0-0.60.0
Condit. Reinf. active responses0.91.22.81.1-1.31.3-1.71.01.4-1.5-0.40.50.3-0.5
Condit. Reinf. inactive responses0.60.92.10.20.00.7-1.20.71.2-1.11.11.11.4-0.8
Condit. Reinf. lever presses2.02.95.82.2-2.42.2-2.01.81.4-1.8-1.90.3-0.6-0.4
Condit. Reinf. lever reinforcers received1.01.43.11.3-1.51.5-1.71.11.4-1.7-0.70.40.2-0.4
Conditioned reinforcement - actives0.83.17.4-0.5-0.5-1.21.5-1.8-2.10.8-1.5-2.7-2.52.3
Conditioned reinforcement - inactives1.43.810.4-0.7-0.4-1.61.3-2.2-2.51.4-1.8-3.2-2.81.5
Conditioned locomotion0.20.20.9-1.00.7-0.50.2-0.8-0.60.10.0-0.00.00.2
Patch foraging indifference point 0 sec0.92.66.3-0.1-0.7-1.20.9-1.1-1.91.7-1.7-2.4-2.51.7
Patch foraging indifference point AUC0.30.72.0-1.31.4-0.60.7-0.8-0.40.01.00.81.0-0.0
Delay disc. indifference point, 0s delay1.61.84.00.10.51.1-1.01.01.6-1.21.52.01.9-1.6
Delay disc. indifference point, 16s delay1.01.44.0-1.62.0-1.01.0-0.7-0.40.81.71.01.1-0.7
Delay disc. indifference point, 2s delay1.31.44.50.20.50.8-0.71.21.5-0.21.32.11.6-1.4
Delay disc. indifference point, 24s delay2.03.28.0-2.52.8-1.91.8-1.8-1.01.92.40.40.9-0.3
Delay disc. indifference point, 4s delay1.21.23.90.00.70.5-0.40.81.30.21.72.01.6-1.1
Delay disc. indifference point, 8s delay0.61.12.9-1.71.7-0.70.7-0.9-0.10.41.31.01.0-0.4
Indifference point function ln k0.20.61.90.1-0.8-0.40.1-0.5-0.50.5-0.7-1.3-1.40.8
Indifference point function log k0.20.61.90.1-0.8-0.40.1-0.5-0.50.5-0.7-1.3-1.40.8
Patch foraging total patch changes 0 sec0.92.65.8-0.4-0.4-1.31.2-1.3-2.11.7-1.7-2.2-2.41.8
Patch foraging total patch changes 12 sec0.10.10.50.2-0.50.2-0.10.10.00.4-0.00.1-0.20.7
Patch foraging total patch changes 18 sec0.71.73.4-1.10.7-1.51.3-1.6-1.91.6-0.5-1.4-1.20.7
Patch foraging total patch changes 24 sec0.10.30.7-0.30.2-0.60.6-0.4-0.80.7-0.4-0.4-0.50.2
Patch foraging total patch changes 6 sec0.50.93.1-0.30.3-1.00.8-0.6-1.31.8-0.6-0.9-1.10.6
Patch foraging time to switch 0 sec0.52.03.61.9-1.31.7-1.61.91.8-1.20.20.90.9-1.4
Patch foraging water rate 0 sec0.62.34.3-2.11.8-1.91.5-1.9-1.91.70.3-0.5-0.41.1
Patch foraging water rate 12 sec0.83.18.1-2.52.8-2.21.7-1.7-1.42.01.80.30.7-0.0
Patch foraging water rate 18 sec4.29.417.0-3.63.2-4.13.8-3.6-3.43.81.3-1.6-1.21.9
Patch foraging water rate 24 sec2.94.27.0-2.31.9-2.72.5-2.5-2.52.40.0-1.5-1.41.2
Patch foraging water rate 6 sec2.84.17.3-2.72.5-2.62.5-2.5-2.22.10.9-0.9-0.41.1
Seeking ratio, delayed vs. immediate footshock0.30.41.40.8-1.20.4-0.20.3-0.0-0.8-0.8-0.8-0.70.2
Distance traveled before self-admin0.30.71.50.4-0.10.8-0.40.91.2-0.91.10.91.1-0.7
Distance traveled after self-admin0.40.72.0-1.01.1-0.10.1-0.10.4-0.60.91.21.4-0.9
Extensor digitorum longus weight0.10.41.00.8-1.00.3-0.40.1-0.1-0.2-0.9-0.8-0.90.4
Bone: elastic displacement0.81.03.30.5-0.61.3-1.21.01.1-1.80.50.91.00.1
Bone: elastic work2.33.15.41.8-1.52.3-1.92.22.2-2.00.21.71.3-0.9
Bone: endosteal estimation1.12.66.72.6-2.61.3-0.21.20.30.2-2.3-1.3-2.00.9
Bone: endosteal perimeter0.61.64.31.2-1.50.10.5-0.1-0.60.6-1.9-1.8-2.11.1
Epididymis fat weight3.618.036.66.1-5.95.5-5.15.04.3-3.9-3.11.0-0.5-1.7
Delta time in closed arm before/after self-admin0.30.30.8-0.50.5-0.50.3-0.5-0.70.9-0.2-0.3-0.40.8
Delta time in open arm before/after self-admin1.51.83.11.8-1.41.7-1.61.61.2-1.5-0.90.30.1-1.4
Diff in mean of infusions in LGA sessions0.81.43.60.20.70.8-0.51.01.3-0.91.81.71.9-0.9
Delay discount exponential model param1.41.95.11.6-2.10.7-0.60.5-0.3-0.8-2.2-1.7-1.71.1
Extinction: sum of active levers before priming0.20.30.7-0.40.1-0.30.4-0.6-0.8-0.1-0.4-0.8-0.60.7
Active lever presses in extinction session 61.71.74.21.5-2.11.6-1.51.10.8-1.7-1.3-0.1-0.40.6
Bone: final force0.20.30.70.8-0.50.7-0.00.80.80.00.10.50.2-0.3
Bone: final moment0.10.20.60.7-0.50.60.10.70.80.00.10.40.2-0.0
Food consumed during 24 hour testing period0.10.10.40.5-0.1-0.0-0.10.40.40.70.40.2-0.1-0.0
Glucose0.91.44.11.4-2.01.1-1.10.50.3-0.9-1.6-0.9-1.31.1
Heart weight0.81.24.41.4-2.11.2-1.01.01.1-0.8-1.1-0.3-0.60.5
Delay discount hyperbolic model param1.21.54.21.2-1.70.4-0.30.1-0.6-0.6-2.1-1.8-1.71.1
Intermittent access intake day 1-15 change0.21.13.01.5-1.71.0-1.10.70.4-0.4-1.2-0.8-1.0-0.1
Intermittent access intake escalation0.10.72.21.3-1.50.8-1.00.60.3-0.3-0.9-0.8-0.90.0
Intermittent access intake escalation 20.60.92.21.5-1.31.0-1.40.90.6-0.2-0.8-0.4-0.6-0.9
Intermitt. access day 1 inactive lever presses0.11.52.9-0.60.1-1.21.0-1.3-1.41.5-0.6-1.7-1.51.5
Intermitt. access day 15 inactive lever presses0.52.99.71.1-1.9-0.2-0.1-0.7-1.30.6-2.3-3.1-2.81.2
Intermitt. access escalation Index0.20.62.50.5-0.81.0-0.40.70.4-1.6-0.90.50.20.7
Intermittent access day 1 total infusions0.00.10.50.1-0.50.5-0.2-0.10.2-0.6-0.0-0.3-0.00.7
Intermittent access day 15 total infusions0.41.03.41.3-1.81.1-1.00.40.5-0.7-0.8-1.0-0.80.8
Intermittent access terminal intake (last 3 days)0.71.33.81.6-2.01.4-1.30.80.8-0.9-0.7-0.8-0.60.7
Intermittent access total infusions0.70.82.61.1-1.61.0-0.90.40.3-0.9-1.1-0.9-0.70.6
Intermittent access day 1 locomotion0.20.41.1-0.90.7-0.00.2-0.30.4-0.41.00.71.00.2
Intermittent access day 15 total locomotion0.10.51.00.6-0.90.9-1.00.50.6-0.9-0.6-0.1-0.1-0.6
Intermittent access total locomotion0.10.10.4-0.30.00.3-0.3-0.10.3-0.60.30.30.5-0.3
Intermittent access standard deviation0.00.20.70.1-0.4-0.1-0.3-0.3-0.30.2-0.4-0.9-0.6-0.0
Left kidney weight0.53.78.32.9-2.82.4-2.12.11.7-1.9-1.70.2-0.4-0.4
Right kidney weight0.21.23.41.7-1.81.1-0.71.10.7-1.0-1.3-0.4-0.60.3
Cocaine induced anxiety0.10.41.2-0.6-0.1-0.50.7-0.8-0.4-0.2-0.4-0.8-0.51.1
Post-drug Anxiety0.30.30.80.8-0.90.7-0.70.60.6-0.6-0.4-0.2-0.2-0.1
Baseline Anxiety1.52.55.41.9-1.21.9-2.32.01.6-1.0-0.01.10.6-2.2
Tail length0.20.92.31.5-1.51.0-0.91.10.8-0.4-1.00.2-0.6-0.4
Length with tail1.14.713.13.5-3.62.3-2.12.31.5-1.0-2.4-0.4-1.50.0
Length without tail0.63.38.83.0-2.92.0-2.12.01.2-0.6-1.8-0.5-1.0-0.3
Times rat made contact with spout2.22.55.22.1-2.32.0-2.01.71.5-1.7-1.10.4-0.2-0.2
Lifetime Intake0.50.71.90.9-1.40.8-0.70.40.1-0.8-1.1-0.8-0.70.5
Liver weight, left0.91.54.32.1-2.01.2-0.91.20.8-0.4-1.6-0.5-1.0-0.1
Liver weight, right1.01.84.62.1-2.11.3-1.71.41.1-0.6-1.3-0.2-0.7-0.5
Locomotor activity0.10.10.40.3-0.50.5-0.60.20.2-0.2-0.30.1-0.00.2
Locomotor testing distance0.00.10.2-0.50.3-0.1-0.3-0.3-0.10.30.10.20.2-0.0
Locomotor testing rearing0.00.20.60.1-0.20.2-0.80.20.10.2-0.80.3-0.0-0.5
Locomotion in novel chamber1.62.24.6-1.50.7-1.61.8-1.7-2.21.1-1.1-1.3-1.31.4
Locomotion in novel chamber post-restriction0.92.65.2-1.81.5-2.02.1-1.9-2.31.7-0.3-0.7-0.81.4
Fecal boli incidents, locomotor time 10.92.33.8-1.00.4-1.82.0-1.7-1.81.8-0.7-1.6-1.71.4
Change in fecal boli incidents, locomotor task0.10.21.2-0.2-0.10.2-0.00.0-0.3-0.5-0.4-0.10.01.1
Time >=10cm from walls, locomotor time 10.40.41.2-0.70.5-0.70.6-0.6-0.71.1-0.1-0.3-0.41.0
Bouts of movement, locomotor time 11.31.63.7-1.21.2-1.71.9-1.6-1.31.50.7-0.9-0.70.4
Total resting periods, locomotor time 12.02.35.1-1.41.3-1.92.3-1.9-1.61.70.7-1.3-1.00.8
Rest time, locomotor task time 10.71.12.7-0.40.2-1.01.4-1.1-1.30.9-0.4-1.6-1.50.8
Distance moved, locomotor task time 10.61.65.1-1.11.5-0.2-0.1-0.00.8-0.12.31.82.2-0.6
Vertical activity count, locomotor time 10.10.71.80.5-0.10.7-0.80.91.1-0.20.51.41.1-0.7
Time >=10cm from walls, locomotor time 20.30.81.81.2-1.41.2-1.20.90.8-0.7-0.90.0-0.4-0.1
Bouts of movement, locomotor time 20.10.41.70.2-0.40.7-0.30.20.9-1.30.30.50.6-0.1
Total resting periods, locomotor time 20.10.31.40.3-0.60.7-0.30.20.8-1.20.00.30.30.1
Rest time, locomotor task time 20.10.20.6-0.0-0.1-0.30.6-0.3-0.40.40.1-0.7-0.50.7
Distance moved, locomotor task time 20.60.82.4-1.01.4-0.60.2-0.50.20.11.50.91.2-0.9
Vertical activity count, locomotor time 20.20.41.1-0.20.60.1-0.50.20.6-0.30.51.00.9-1.0
Light reinforcement 10.21.02.40.1-0.3-0.80.9-0.8-1.21.1-1.0-1.3-1.51.0
Light reinforcement 20.92.04.9-0.0-1.1-0.61.0-1.1-1.5-0.7-2.2-1.8-2.11.8
Bone: marrow area1.12.66.82.5-2.61.3-0.21.10.30.1-2.3-1.4-2.10.9
Bone: maximum diameter0.40.92.51.6-1.50.7-0.60.70.50.1-1.0-1.0-1.1-0.3
Bone: maximum force0.10.20.70.8-0.40.40.00.60.50.5-0.00.10.1-0.2
Bone: maximum moment0.10.20.60.7-0.30.40.10.60.50.40.10.20.2-0.0
Mean time between licks in bursts0.10.41.7-0.70.8-0.81.3-0.5-0.70.7-0.3-0.2-0.10.3
Mean num. licks in bursts0.41.03.61.1-1.91.0-1.10.50.5-1.1-0.9-0.6-0.81.0
Cd content in liver0.30.32.30.10.6-0.30.30.2-0.11.50.30.3-0.1-0.2
Co content in liver0.50.62.7-0.80.2-0.70.8-1.0-0.80.60.0-0.5-0.61.6
Cu content in liver0.40.40.8-0.60.5-0.70.9-0.8-0.40.70.8-0.6-0.20.5
Fe content in liver1.01.22.21.3-0.91.4-1.41.31.5-1.00.10.80.8-1.0
K content in liver1.71.74.4-1.81.9-0.60.6-0.40.3-0.12.11.31.9-0.9
Mg content in liver0.20.20.7-0.20.20.2-0.40.20.3-0.60.30.30.7-0.8
Mn content in liver1.41.62.8-1.2-0.1-1.01.4-1.5-1.5-0.2-1.3-1.5-1.31.7
Na content in liver1.41.63.3-0.10.11.0-1.70.81.3-1.70.91.51.8-1.3
Rb content in liver0.20.30.80.60.10.2-0.10.50.50.70.60.20.4-0.9
Se content in liver0.50.61.30.3-0.00.7-0.80.91.1-0.31.11.11.1-0.2
Sr content in liver0.80.71.4-0.70.4-0.91.0-1.0-1.00.7-0.3-0.7-0.81.2
Zn content in liver0.40.41.2-0.71.0-0.5-0.1-0.30.20.61.10.80.8-0.3
Bone: minimum diameter0.30.61.41.1-1.20.9-0.90.80.7-0.5-0.7-0.1-0.30.3
Time in familiar zone, hab. session 10.80.92.00.40.50.7-0.61.01.0-0.41.21.41.4-0.8
Time in novel zone, hab. session 10.60.62.50.2-0.9-0.1-0.2-0.3-0.50.2-1.6-1.1-1.3-0.1
Total zone transitions, hab. session 10.71.02.8-1.30.9-1.01.7-1.1-0.80.10.8-0.4-0.01.4
Total locomotion distance, hab. session 10.91.32.6-1.61.2-1.41.5-1.6-1.00.51.1-0.7-0.11.0
Locomotion velocity, hab. session 11.31.83.5-1.91.5-1.61.8-1.7-1.10.61.3-0.40.11.2
Time in familiar zone, hab. session 20.10.20.4-0.30.1-0.30.1-0.5-0.6-0.1-0.6-0.6-0.40.2
Time in novel zone, hab. session 20.30.30.90.9-0.90.7-0.50.80.5-0.3-0.40.2-0.3-0.1
Total zone transitions, hab. session 20.50.71.9-0.2-0.4-0.51.1-0.6-0.70.2-0.9-0.9-1.11.4
Total locomotion distance, hab. session 21.72.23.9-0.8-0.2-1.21.5-1.6-1.80.7-1.6-1.9-2.01.9
Locomotion velocity, hab. session 21.82.43.8-1.30.3-1.51.8-1.8-1.90.9-1.2-1.7-1.71.9
Novel to familiar place preference ratio0.20.21.90.40.00.0-0.00.3-0.20.4-0.3-0.3-0.3-1.4
Novelty place preference0.20.32.70.40.20.1-0.00.4-0.00.4-0.20.0-0.0-1.6
Time in novel zone, NPP test0.30.42.50.8-0.30.4-0.20.70.10.2-0.6-0.1-0.2-1.6
Total zone transitions, NPP test0.60.92.6-1.10.7-0.91.6-1.0-0.80.40.3-0.6-0.41.5
Total locomotion distance, NPP test1.72.44.5-1.40.6-1.71.8-1.9-1.91.2-0.7-1.6-1.52.1
Locomotion velocity, NPP test1.92.74.6-1.81.0-1.92.1-2.0-1.91.3-0.3-1.4-1.32.1
Intraocular pressure1.62.65.5-1.00.8-1.92.3-1.7-2.12.0-0.4-1.6-1.61.4
Delta distance traveled before/after self-admin0.50.61.6-1.31.3-0.60.3-0.6-0.60.2-0.10.80.7-0.9
Delta ambulatory time before/after self-admin0.30.51.2-1.11.1-0.70.3-0.7-0.70.4-0.30.60.3-1.0
Parametrial fat weight12.529.460.17.8-7.27.0-6.36.35.4-5.6-3.91.6-0.3-2.0
Pavlov. Cond. lever latency2.43.08.31.7-2.70.9-0.70.2-0.3-1.4-2.9-2.2-2.31.0
Pavlov. Cond. magazine entry latency0.81.02.90.10.60.6-1.00.91.0-0.51.11.71.6-1.0
Pavlov. Cond. change in total contacts3.13.48.3-1.62.9-0.90.2-0.10.31.52.92.42.5-1.6
Pavlov. Cond. index score2.22.87.1-1.02.2-0.2-0.40.50.90.52.62.62.7-1.6
Pavlov. Cond. latency score2.33.07.3-1.52.6-0.60.10.10.50.82.72.52.6-1.4
Pavlov. Cond. lever contacts1.92.27.1-1.02.0-0.30.10.30.70.92.72.22.3-1.0
Pavlov. Cond. magazine entry number1.11.33.90.0-0.9-0.50.9-0.9-1.10.1-1.5-2.0-1.81.2
Pavlov. Cond. intertrial magazine entries3.03.78.3-0.4-0.7-1.31.5-1.8-2.30.8-2.4-2.9-2.82.2
Pavlov. Cond. lever-magazine prob. diff.2.73.38.7-0.92.20.0-0.60.71.20.42.82.93.0-1.9
Pavlov. Cond. response bias1.72.15.5-0.21.40.4-0.81.01.30.32.22.32.3-1.6
Pavlov. Cond. lever latency2.53.57.2-2.72.4-2.42.2-2.4-2.11.61.0-0.9-0.00.8
Pavlov. Cond. magazine entry latency1.82.57.02.1-2.71.2-0.90.90.3-0.8-2.5-1.3-2.00.8
Pavlov. Cond. change in total contacts2.04.99.23.0-2.83.0-2.62.72.5-2.3-1.30.90.2-0.3
Pavlov. Cond. index score2.64.19.23.0-3.02.5-2.22.31.8-1.7-1.90.2-0.7-0.3
Pavlov. Cond. latency score2.03.37.02.7-2.52.3-2.12.11.7-1.6-1.50.4-0.4-0.4
Pavlov. Cond. lever contacts2.53.88.12.8-2.52.5-2.22.42.1-1.7-1.30.7-0.1-0.9
Pavlov. Cond. magazine entry number2.12.87.5-2.52.7-1.81.5-1.5-1.21.31.90.61.2-0.5
Pavlov. Cond. intertrial magazine entries0.71.54.4-1.72.1-1.20.5-0.8-0.61.01.40.91.1-1.1
Pavlov. Cond. lever-magazine prob. diff.3.04.59.63.1-3.02.7-2.42.52.1-2.1-1.70.5-0.4-0.4
Pavlov. Cond. response bias2.94.09.93.1-3.22.4-2.02.11.6-1.5-2.1-0.2-1.1-0.2
Time in closed arm before self-admin0.10.21.00.3-0.5-0.10.3-0.2-0.10.0-0.0-0.5-0.51.0
Time in closed arm after self-admin0.81.03.5-0.50.1-0.90.9-1.1-1.00.9-0.1-1.1-1.01.9
Time in open arm before self-admin0.20.30.8-0.40.30.3-0.40.30.4-0.50.10.90.8-0.7
Time in open arm after self-admin1.92.15.41.0-0.81.8-1.61.61.6-2.3-0.21.11.3-1.5
Bone: periosteal estimation0.61.33.91.9-2.01.2-0.61.00.7-0.2-1.3-0.7-1.10.3
Bone: periosteal perimeter0.30.61.50.9-1.20.3-0.00.2-0.0-0.1-1.2-1.0-1.10.3
Bone: post-yield work0.20.41.10.4-0.1-0.40.4-0.2-0.61.0-0.6-1.1-0.80.7
Progressive ratio test 1 active lever presses0.20.41.20.8-1.10.8-0.60.50.4-0.8-0.6-0.4-0.20.5
Progressive ratio test 1 breakpoint0.30.51.20.9-1.10.9-0.60.60.5-0.8-0.5-0.4-0.20.5
Progressive ratio test 1 inactive lever presses0.51.44.50.5-1.0-0.40.2-0.6-1.20.8-1.7-2.1-2.10.5
Progressive ratio test 2 active lever presses0.20.31.00.7-1.00.5-0.50.20.2-0.5-0.5-0.7-0.50.2
Progressive ratio test 2 breakpoint0.30.41.30.8-1.10.6-0.60.20.3-0.6-0.6-0.8-0.50.3
Progressive ratio test 2 inactive lever presses0.62.06.41.3-2.10.6-0.70.0-0.4-0.6-2.5-1.9-2.10.1
Incentive Sensitization - Responses0.20.41.50.3-0.80.00.0-0.2-0.5-0.4-1.2-1.0-1.00.2
Incentive Sensitization - Breakpoint0.20.52.00.5-1.00.2-0.2-0.1-0.4-0.6-1.4-1.0-1.10.3
Sum of active levers in priming session hrs 5-60.60.52.0-0.40.1-0.40.7-0.7-0.90.0-0.3-1.0-0.71.4
Progressive ratio1.02.95.7-1.10.4-1.81.9-1.8-2.41.2-1.3-2.1-1.92.0
Food seeking constrained by brief footshock0.81.02.6-1.61.5-0.71.1-0.8-0.4-0.41.20.41.10.7
Seeking ratio, punishment vs. effort1.33.05.30.8-0.11.8-1.61.72.3-2.01.42.12.2-1.6
Retroperitoneal fat weight12.154.2111.610.6-9.29.6-8.99.28.0-6.6-3.72.90.7-3.6
Reaction time number correct0.72.64.5-1.41.0-2.02.1-1.8-2.11.8-1.1-1.4-1.70.7
Reaction time mean minus median0.32.04.42.1-2.11.7-1.51.71.0-1.4-1.3-0.0-0.40.1
Reaction time mean minus median AUC0.31.84.21.9-2.01.5-1.31.50.6-1.0-1.8-0.2-0.80.1
Reaction time num false alarms1.22.14.3-2.11.3-1.81.5-2.0-1.11.31.1-0.6-0.31.5
Reaction time num false alarms AUC0.71.73.9-2.01.3-1.71.3-1.8-1.01.21.1-0.4-0.21.1
Reaction time trials correct on left0.72.64.5-1.41.0-2.02.1-1.8-2.11.8-1.1-1.4-1.70.7
Reaction time trials on left0.82.64.5-1.40.9-2.02.0-1.8-2.11.8-1.3-1.4-1.80.7
Reaction time mean1.53.27.62.8-2.62.3-1.72.21.6-1.9-1.40.2-0.4-0.1
Reaction time mean AUC1.12.75.82.4-2.42.1-1.62.01.5-1.9-1.20.3-0.20.2
Median of all reaction times1.72.66.12.5-2.32.1-1.42.11.6-1.7-1.10.3-0.3-0.1
Reaction time omissions0.50.83.61.3-1.30.6-0.20.70.0-0.3-1.9-0.5-1.00.1
Reaction time false alarm rate0.40.51.8-1.10.7-0.60.3-0.9-0.10.31.30.00.40.7
Reaction time premature initiation rate0.10.20.5-0.1-0.2-0.30.5-0.4-0.30.40.1-0.6-0.60.7
Reaction time premature initiations0.51.42.2-0.90.3-1.31.5-1.4-1.41.2-0.4-1.3-1.41.1
Std. dev. reaction times0.72.45.72.4-2.21.9-1.72.01.3-1.4-1.30.1-0.3-0.2
Reaction time trials completed0.82.64.5-1.40.9-2.02.0-1.8-2.11.8-1.3-1.4-1.80.7
Reaction time trials AUC0.93.15.3-1.30.8-2.12.2-1.9-2.32.0-1.4-1.7-2.10.8
Run reversals in cocaine runway, females1.82.03.61.4-1.31.7-1.91.81.5-1.4-0.91.30.6-1.1
Run reversals in cocaine runway, males2.22.44.91.4-0.61.6-2.01.72.2-0.81.11.91.7-1.4
Latency to leave start box in cocaine runway0.60.81.5-0.7-0.2-0.60.8-1.1-1.10.0-1.1-1.1-1.01.2
Latency to leave start box in cocaine runway, F0.30.41.40.2-0.7-0.1-0.0-0.5-0.50.3-1.0-1.0-1.20.4
Latency to leave start box in cocaine runway, M1.41.34.0-1.30.3-1.01.5-1.3-1.4-0.3-0.9-1.0-0.62.0
Std. dev. time between licks in bursts0.40.71.6-1.11.3-1.01.3-0.8-0.91.00.30.20.10.3
Total sessions with >9 infusions0.50.61.60.9-1.30.9-0.90.50.4-1.0-1.1-0.4-0.40.2
Short access day 1 total inactive lever presses1.22.46.1-0.2-0.6-1.11.0-1.5-1.91.3-1.8-2.4-2.51.4
Short access day 10 total inactive lever presses0.42.68.20.3-1.1-0.80.6-1.1-1.71.3-2.4-2.4-2.91.1
Short access day 1 total infusions0.30.71.3-0.70.3-1.00.7-1.0-1.10.8-0.5-1.1-0.90.6
Short access day 10 total infusions0.30.41.20.6-1.00.5-0.50.0-0.2-0.2-1.1-0.9-0.90.6
Short access total infusions0.30.51.20.8-1.10.7-0.80.40.1-0.6-1.1-0.6-0.60.3
Short access day 1 locomotion0.10.20.60.2-0.50.4-0.80.20.3-0.7-0.60.1-0.0-0.3
Short access day 10 total locomotion0.10.51.7-0.70.7-0.90.5-0.8-0.81.3-0.0-0.5-0.50.4
Short access total locomotion0.10.10.3-0.60.4-0.1-0.1-0.20.2-0.20.30.50.5-0.1
One hour access (0.3 mA shock)0.50.61.70.1-0.50.3-0.2-0.4-0.9-0.9-1.1-1.3-0.90.9
Compulsive drug intake0.81.23.2-1.41.8-1.01.4-1.1-1.50.20.5-0.40.10.9
One hour access (shock baseline)0.30.71.91.0-1.41.0-1.40.70.7-0.6-0.6-0.4-0.3-0.5
Social response proportion2.83.66.02.2-2.22.4-2.42.31.8-2.4-1.31.10.4-0.4
Social responses0.20.20.70.5-0.50.3-0.80.60.70.10.10.40.1-0.6
Social time0.61.01.90.9-0.91.2-1.01.21.4-0.8-0.31.20.6-0.8
Soleus weight0.00.10.40.2-0.2-0.1-0.0-0.1-0.40.3-0.5-0.5-0.70.2
Bone: stiffness0.10.20.70.5-0.3-0.20.4-0.1-0.10.8-0.4-0.5-0.5-0.1
Tibialis anterior weight0.41.23.41.8-1.41.3-1.41.30.8-0.7-1.00.0-0.3-0.7
Time to tail flick, vehicle, before self-admin1.62.05.71.7-2.41.0-0.50.50.0-1.0-1.8-1.5-1.61.7
Time to tail flick, vehicle, after self-admin0.20.31.6-0.00.0-0.30.1-0.30.20.61.2-0.5-0.11.3
Time to tail flick, test, before self-admin0.10.21.00.00.1-0.10.5-0.2-0.2-0.10.4-0.5-0.11.0
Time to tail flick, test, after self-admin2.32.57.30.0-0.5-1.21.1-1.3-1.71.8-1.2-2.7-2.51.2
Delta time to tail flick, vehicle, before/after SA0.91.02.8-1.11.3-1.30.7-0.9-0.51.71.4-0.20.1-0.1
Delta time to tail flick, test, before/after SA0.60.72.0-0.1-0.3-0.80.5-0.7-0.91.1-1.0-1.3-1.4-0.0
Tibia length1.44.07.92.8-2.82.7-1.92.42.4-2.1-0.50.80.30.7
Ambulatory time before self-admin0.30.91.80.7-0.41.0-0.71.11.3-1.00.80.91.0-0.6
Ambulatory time after self-admin0.50.92.2-0.91.1-0.1-0.00.10.4-0.30.91.41.5-1.5
Bone: tissue strength0.50.51.10.9-0.61.1-0.81.00.7-0.7-0.30.80.30.2
Total heroin consumption1.11.33.50.1-1.10.00.3-0.5-0.9-0.5-1.9-1.6-1.61.9
Bone: trabecular number0.10.20.6-0.70.8-0.50.1-0.2-0.20.60.50.50.5-0.1
Bone: trabecular spacing1.21.73.31.8-1.41.6-1.81.41.7-1.00.10.20.4-1.3
Bone: trabecular thickness0.20.20.5-0.50.7-0.30.6-0.2-0.20.20.50.60.40.7
Bone: trabecular tissue density0.81.33.90.50.11.1-1.01.11.4-0.80.91.41.5-2.0
Water consumed over 24 hours0.40.82.50.4-1.0-0.2-0.1-0.4-0.60.5-1.1-1.3-1.61.0
Number of responses in last shaping day0.91.22.7-0.50.2-1.30.7-1.2-1.51.4-0.4-1.6-1.40.4