Hub : Traits : Body weight : ← : →

chr18:25,166,673-27,022,191

Trait: Body weight

Best TWAS P=4.21e-11 · Best GWAS P=3.34e-10 conditioned to 1.00e+00

Associated models

Tissue	Gene	RNA modality	RNA phenotype	h2	# weights	Model R2	Model R2 P	TWAS Z	TWAS P	Coloc P	Joint
Adipose	Reep5	alternative polyA	ENSRNOT00000027345	0.11	1161	0.11	2.3e-12	-5.19	2.09e-07	0.61	FALSE
Adipose	Reep5	alternative polyA	ENSRNOT00000108864	0.11	1	0.12	6.8e-13	5.21	1.86e-07	0.01	FALSE
Adipose	Cdc23	alternative polyA	ENSRNOT00000037888	0.17	1	0.12	1.2e-13	6.22	4.84e-10	0.79	FALSE
Adipose	Cdc23	alternative polyA	ENSRNOT00000101231	0.16	37	0.12	7.2e-13	-5.19	2.11e-07	0.68	TRUE
Adipose	Cdc23	alternative polyA	ENSRNOT00000101231	0.05	1	0.03	2.9e-04	-5.14	2.69e-07	0.03	FALSE
Adipose	Cdc23	alternative polyA	ENSRNOT00000114348	0.05	1	0.03	3.5e-04	5.14	2.69e-07	0.03	FALSE
Adipose	Fam13b	gene expression	ENSRNOG00000020384	0.14	22	0.15	1.7e-16	5.36	8.36e-08	0.6	FALSE
Adipose	Cdc23	gene expression	ENSRNOG00000024241	0.05	835	0.03	1.1e-04	5.98	2.28e-09	0.67	FALSE
Adipose	Kif20a	gene expression	ENSRNOG00000024428	0.03	1	0.01	7.9e-03	5.09	3.52e-07	0.03	FALSE
Adipose	Reep5	isoform ratio	ENSRNOT00000027345	0.11	1	0.12	1.1e-13	-5.21	1.86e-07	0.01	FALSE
Adipose	Reep5	isoform ratio	ENSRNOT00000108864	0.1	1	0.12	3.9e-13	5.21	1.86e-07	0.01	FALSE
Adipose	Cdc23	isoform ratio	ENSRNOT00000037888	0.03	835	0.02	4.9e-03	6	1.94e-09	0.54	FALSE
Adipose	Cdc23	isoform ratio	ENSRNOT00000101231	0.14	835	0.11	2.3e-12	-5.89	3.76e-09	0.68	FALSE
Adipose	Fam13b	intron excision ratio	chr18:26065107:26067320	0.02	1	0.03	1.6e-04	-5.14	2.69e-07	0.03	FALSE
Adipose	Fam13b	mRNA stability	ENSRNOG00000020384	0.1	1	0.13	1.3e-14	5.39	6.98e-08	0.03	FALSE
Adipose	Cdc23	mRNA stability	ENSRNOG00000024241	0.06	835	0.04	1.5e-05	5.8	6.83e-09	0.67	FALSE
BLA	Reep5	alternative polyA	ENSRNOT00000027345	0.16	66	0.21	2.6e-11	-5.28	1.32e-07	0.69	FALSE
BLA	Cdc23	alternative polyA	ENSRNOT00000101231	0.13	21	0.13	3.3e-07	-6.11	9.76e-10	0.71	FALSE
BLA	Reep5	gene expression	ENSRNOG00000020167	0.15	1	0.14	3.9e-08	6.11	9.76e-10	0.64	FALSE
BLA	Reep5	isoform ratio	ENSRNOT00000027345	0.19	31	0.25	1.6e-13	-5.23	1.70e-07	0.71	FALSE
BLA	Cdc23	isoform ratio	ENSRNOT00000101231	0.1	835	0.09	1.6e-05	-5.96	2.49e-09	0.7	FALSE
BLA	Reep5	intron excision ratio	chr18:25947663:25949991	0.06	1	0.04	1.9e-03	-6.13	8.79e-10	0.05	FALSE
BLA	Reep5	intron excision ratio	chr18:25950159:25957916	0.08	1	0.06	2.3e-04	6.13	8.79e-10	0.07	FALSE
BLA	Reep5	mRNA stability	ENSRNOG00000020167	0.05	1162	0.02	4.6e-02	5.68	1.38e-08	0.41	FALSE
Brain	Reep5	alternative polyA	ENSRNOT00000027345	0.07	1	0.07	7.0e-07	-6.11	1.02e-09	0.62	FALSE
Brain	Reep5	alternative polyA	ENSRNOT00000108864	0.06	1	0.06	1.5e-06	6.11	1.02e-09	0.59	FALSE
Brain	Cdc23	alternative polyA	ENSRNOT00000037888	0.08	835	0.07	2.0e-07	5.89	3.88e-09	0.64	FALSE
Brain	Cdc23	alternative polyA	ENSRNOT00000101231	0.08	835	0.1	3.6e-09	-6.01	1.83e-09	0.7	FALSE
Brain	Cdc23	alternative polyA	ENSRNOT00000101231	0.03	835	0.02	8.4e-03	-5.34	9.25e-08	0.38	TRUE
Brain	Cdc23	alternative polyA	ENSRNOT00000114348	0.03	835	0.02	8.8e-03	5.34	9.38e-08	0.38	FALSE
Brain	Brd8	gene expression	ENSRNOG00000020340	0.02	1	0.03	8.8e-04	5.22	1.83e-07	0.03	FALSE
Brain	Cdc23	gene expression	ENSRNOG00000024241	0.03	1	0.03	5.8e-04	6.26	3.83e-10	0.18	FALSE
Brain	Cdc23	isoform ratio	ENSRNOT00000101231	0.08	835	0.1	3.8e-09	-5.96	2.57e-09	0.71	FALSE
Brain	Reep5	intron excision ratio	chr18:25947663:25949991	0.03	1	0.02	7.1e-03	-6.1	1.09e-09	0.04	FALSE
Brain	Reep5	intron excision ratio	chr18:25950159:25957916	0.03	1162	0.03	1.6e-03	5.1	3.32e-07	0.64	FALSE
Brain	Apc	intron excision ratio	chr18:25828942:25871423	0.05	112	0.07	2.5e-07	5.77	8.05e-09	0.69	FALSE
Brain	Apc	intron excision ratio	chr18:25864409:25871423	0.07	1199	0.02	7.0e-03	5.73	9.90e-09	0.55	FALSE
Brain	Apc	intron excision ratio	chr18:25869365:25871423	0.02	1199	0.03	1.7e-03	-5.18	2.27e-07	0.57	FALSE
Brain	Cdc23	intron excision ratio	chr18:26240165:26240396	0.03	1	0.03	1.1e-03	-5.46	4.83e-08	0.03	FALSE
Brain	Cdc23	mRNA stability	ENSRNOG00000024241	0.02	835	0.01	4.2e-02	5.76	8.62e-09	0.5	FALSE
Eye	Fam13b	gene expression	ENSRNOG00000020384	0.57	578	0.24	1.5e-04	5.59	2.26e-08	0.3	TRUE
Eye	Apc	isoform ratio	ENSRNOT00000102176	0.28	1	0.11	9.7e-03	5.82	5.81e-09	0.06	FALSE
IL	Cdc23	alternative polyA	ENSRNOT00000037888	0.27	1	0.03	7.0e-02	6.19	5.98e-10	0.06	FALSE
IL	Brd8	gene expression	ENSRNOG00000020340	0.2	1	0.08	7.2e-03	6.15	7.64e-10	0.06	FALSE
IL	Cdc23	isoform ratio	ENSRNOT00000101231	0.17	834	0.03	7.3e-02	-5.96	2.58e-09	0.3	FALSE
LHb	Cdc23	alternative polyA	ENSRNOT00000101231	0.21	1	0.05	2.7e-02	-5.49	4.04e-08	0.05	FALSE
LHb	Cdc23	gene expression	ENSRNOG00000024241	0.29	1	0.15	1.8e-04	6.15	7.64e-10	0.07	FALSE
LHb	Cdc23	isoform ratio	ENSRNOT00000101231	0.18	1	0.06	1.3e-02	-6.22	5.12e-10	0.06	FALSE
LHb	Cdc23	mRNA stability	ENSRNOG00000024241	0.23	1	0.12	9.7e-04	6.15	7.64e-10	0.06	FALSE
Liver	Cdc23	alternative polyA	ENSRNOT00000037888	0.15	835	0.11	5.0e-12	6	2.03e-09	0.68	FALSE
Liver	Cdc23	alternative polyA	ENSRNOT00000101231	0.17	835	0.12	2.2e-13	-5.97	2.41e-09	0.68	FALSE
Liver	Cdc23	alternative polyA	ENSRNOT00000101231	0.05	1	0.04	2.1e-05	-5.47	4.46e-08	0.03	FALSE
Liver	Cdc23	alternative polyA	ENSRNOT00000114348	0.05	1	0.04	3.4e-05	5.47	4.46e-08	0.03	FALSE
Liver	Srp19	gene expression	ENSRNOG00000020204	0.04	1227	0.02	3.9e-03	6.01	1.82e-09	0.54	FALSE
Liver	Fam13b	gene expression	ENSRNOG00000020384	0.14	1001	0.13	2.8e-14	6.05	1.43e-09	0.61	FALSE
Liver	Cdc23	gene expression	ENSRNOG00000024241	0.19	835	0.14	6.0e-15	5.97	2.44e-09	0.68	FALSE
Liver	Pkd2l2	gene expression	ENSRNOG00000025489	0.03	1	0.02	1.3e-03	6.22	4.84e-10	0.06	FALSE
Liver	Gfra3	isoform ratio	ENSRNOT00000114917	0.03	1	0.02	4.7e-03	-5.8	6.62e-09	0.54	FALSE
Liver	Cdc23	isoform ratio	ENSRNOT00000037888	0.04	1	0.03	5.5e-04	5.47	4.46e-08	0.03	FALSE
Liver	Cdc23	isoform ratio	ENSRNOT00000101231	0.2	835	0.15	7.8e-16	-5.99	2.07e-09	0.68	FALSE
Liver	Srp19	intron excision ratio	chr18:25931783:25935915	0.03	1227	0.02	1.8e-03	-5.61	2.08e-08	0.54	FALSE
Liver	ENSRNOG00000062486	intron excision ratio	chr18:25931783:25935915	0.03	1227	0.02	1.8e-03	-5.61	2.08e-08	0.54	FALSE
Liver	Reep5	mRNA stability	ENSRNOG00000020167	0.05	1	0.04	9.1e-06	6.22	4.84e-10	0.69	FALSE
Liver	Cdc23	mRNA stability	ENSRNOG00000024241	0.04	16	0.03	5.7e-04	6.23	4.70e-10	0.64	TRUE
NAcc	Reep5	alternative polyA	ENSRNOT00000027345	0.07	28	0.09	3.4e-07	-6.2	5.59e-10	0.7	FALSE
NAcc	Reep5	alternative polyA	ENSRNOT00000108864	0.07	31	0.09	6.5e-07	6.2	5.67e-10	0.7	FALSE
NAcc	Cdc23	alternative polyA	ENSRNOT00000037888	0.06	1	0.05	2.3e-04	5.2	2.00e-07	0.03	FALSE
NAcc	Cdc23	alternative polyA	ENSRNOT00000101231	0.08	1	0.07	5.6e-06	-6.24	4.40e-10	0.64	FALSE
NAcc	Pkd2l2	gene expression	ENSRNOG00000025489	0.04	1097	0.04	1.3e-03	5.31	1.07e-07	0.64	FALSE
NAcc	Epb41l4a	gene expression	ENSRNOG00000026050	0.07	1032	0.02	1.7e-02	6.3	2.96e-10	0.43	TRUE
NAcc	Cdc23	isoform ratio	ENSRNOT00000101231	0.07	834	0.06	2.4e-05	-5.82	6.03e-09	0.7	FALSE
NAcc	Nme5	mRNA stability	ENSRNOG00000020118	0.04	908	0.04	4.5e-04	6.03	1.68e-09	0.66	FALSE
OFC	Reep5	isoform ratio	ENSRNOT00000027345	0.9	1	0.03	8.5e-02	-5.49	4.04e-08	0.05	FALSE
PL	Cdc23	alternative polyA	ENSRNOT00000101231	0.08	4	0.06	2.8e-05	-5.29	1.20e-07	0.67	FALSE
PL	Reep5	gene expression	ENSRNOG00000020167	0.14	1160	0.13	2.1e-10	6.6	4.21e-11	0.69	TRUE
PL	Brd8	gene expression	ENSRNOG00000020340	0.06	1	0.02	7.0e-03	5.46	4.83e-08	0.04	FALSE
PL	Apc	gene expression	ENSRNOG00000020423	0.05	1184	0.03	1.4e-03	-5.28	1.27e-07	0.56	FALSE
PL	Reep5	isoform ratio	ENSRNOT00000027345	0.1	1160	0.13	9.5e-10	-5.41	6.16e-08	0.66	FALSE
PL	Reep5	isoform ratio	ENSRNOT00000108864	0.1	1160	0.13	7.3e-10	5.56	2.73e-08	0.66	FALSE
PL	Apc	isoform ratio	ENSRNOT00000027691	0.03	1	0.03	3.1e-03	-6.05	1.46e-09	0.04	FALSE
PL	Apc	isoform ratio	ENSRNOT00000102176	0.03	1	0.03	1.2e-03	6.05	1.46e-09	0.05	FALSE
PL	Nme5	intron excision ratio	chr18:26169875:26180166	0.05	908	0.04	2.6e-04	5.95	2.65e-09	0.65	FALSE
PL	Apc	intron excision ratio	chr18:25828942:25871423	0.04	1184	0.03	3.0e-03	5.69	1.31e-08	0.48	FALSE
PL	Apc	intron excision ratio	chr18:25855715:25856649	0.05	1184	0.05	1.5e-04	-5.57	2.57e-08	0.66	FALSE
PL	Cdc23	intron excision ratio	chr18:26240669:26242295	0.05	1	0.04	3.2e-04	6.23	4.70e-10	0.14	FALSE