Best TWAS P=1.382386e-07 · Best GWAS P=2.937102e-06 conditioned to 0.1376733
| # | Tissue | Gene | Modality | RNA phenotype | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | Adipose | Prr14l | intron excision ratio | chr14:77870041:77879708 | 0.05 | 0.01 | enet | 179 | 0.02 | 0.0057 | -3.1 | 5.3 | 1.4e-07 | 0.68 | 0.33 | 0.41 | TRUE |
h2: Heritability estimate for the given transcriptomic model. PP3: Posterior probability of two distinct causal variants. PP4: Posterior probability of a single shared causal variant. joint: Whether the RNA phenotype is in the joint model.