Best TWAS P = 8.36e-08 · Best GWAS P= 1.17e-07 conditioned to 1.00e+00
| Tissue | Gene | RNA modality | RNA phenotype | h2 | # weights | Model R2 | Model R2 P | TWAS Z | TWAS P | Coloc P | Joint |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Adipose | Ret | mRNA stability | Ret | 0.03 | 3049 | 0.01 | 6.6e-02 | 5.24 | 1.64e-07 | 0.36 | FALSE |
| IC | Rasgef1a | intron excision ratio | chr4_152860033_152929341 | 0.2 | 61 | 0.16 | 4.4e-07 | 5.36 | 8.36e-08 | 0.8 | TRUE |
| PL | Rasgef1a | alternative TSS | XM_006237211.5 | 0.15 | 32 | 0.13 | 1.5e-13 | 5.25 | 1.49e-07 | 0.83 | TRUE |
| PL | Rasgef1a | alternative TSS | XM_006237211.5 | 0.24 | 2924 | 0.22 | 1.0e-23 | 5.34 | 9.31e-08 | 0.81 | FALSE |
| PL | Rasgef1a | isoform ratio | XM_006237211.5 | 0.2 | 2924 | 0.18 | 2.0e-19 | 5.33 | 9.87e-08 | 0.82 | FALSE |