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chr6:96,850,756-98,793,722

Trait: Body weight

Best TWAS P=1.479845e-08 · Best GWAS P=2.332971e-08 conditioned to 0.2042008

Associated models

#	Tissue	Gene	Modality	RNA phenotype	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	Adipose	Pigh	gene expression	ENSRNOG00000010914	0.11	0.02	enet	17	0.07	3.4e-08	4.5	5.6	2.4e-08	-0.75	0.49	0.51	FALSE
2	BLA	Pigh	alternative polyA	ENSRNOT00000014775	0.12	0.04	enet	30	0.06	5.1e-04	-5.3	-5.5	5.0e-08	0.81	0.30	0.62	FALSE
3	BLA	Pigh	alternative polyA	ENSRNOT00000101349	0.16	0.05	blup	2175	0.07	8.8e-05	-5.3	5.3	1.5e-07	-0.77	0.29	0.69	FALSE
4	BLA	Pigh	gene expression	ENSRNOG00000010914	0.25	0.14	enet	114	0.20	5.3e-11	-5.3	5.5	3.2e-08	-0.93	0.09	0.91	FALSE
5	BLA	Arg2	gene expression	ENSRNOG00000053811	0.20	0.17	top1	1	0.17	2.4e-09	-5.3	5.3	1.5e-07	-0.92	0.11	0.88	FALSE
6	BLA	Pigh	isoform ratio	ENSRNOT00000014775	0.19	0.09	enet	119	0.13	2.8e-07	-5.3	-5.4	7.5e-08	0.84	0.25	0.75	FALSE
7	BLA	Pigh	isoform ratio	ENSRNOT00000101349	0.18	0.10	enet	156	0.11	1.0e-06	-5.3	5.6	1.8e-08	-0.89	0.14	0.86	FALSE
8	BLA	Arg2	mRNA stability	ENSRNOG00000053811	0.15	0.12	top1	1	0.12	5.8e-07	-5.3	5.3	1.0e-07	-0.97	0.08	0.86	FALSE
9	Brain	Atp6v1d	mRNA stability	ENSRNOG00000009080	0.09	0.01	blup	1744	0.04	3.0e-04	-5.5	-5.5	4.6e-08	0.94	0.04	0.94	FALSE
10	IL	Mpp5	mRNA stability	ENSRNOG00000008788	0.65	0.23	blup	1508	0.29	1.2e-07	-4.8	5.2	2.0e-07	-0.91	0.04	0.96	FALSE
11	Liver	Pigh	isoform ratio	ENSRNOT00000101349	0.03	0.00	blup	2174	0.00	9.9e-02	-5.0	5.7	1.5e-08	-0.88	0.19	0.57	TRUE
12	NAcc	Zfyve26	intron excision ratio	chr6:98082700:98083733	0.33	0.21	enet	95	0.23	3.9e-17	2.4	5.2	1.5e-07	-0.72	1.00	0.00	FALSE
13	NAcc	Zfyve26	intron excision ratio	chr6:98082703:98083733	0.34	0.21	enet	96	0.23	2.0e-17	2.4	-5.4	7.5e-08	0.72	1.00	0.00	FALSE
14	OFC	Pigh	gene expression	ENSRNOG00000010914	0.28	0.10	lasso	15	0.11	1.3e-03	-4.8	5.1	2.7e-07	-0.94	0.14	0.71	FALSE
15	PL	Pigh	isoform ratio	ENSRNOT00000014775	0.10	0.07	top1	1	0.07	2.9e-06	-5.3	-5.3	9.5e-08	0.90	0.07	0.90	FALSE
16	PL	Pigh	isoform ratio	ENSRNOT00000101349	0.13	0.08	blup	2174	0.09	3.6e-07	-5.0	5.6	2.3e-08	-0.92	0.05	0.95	FALSE
17	PL	Mpp5	mRNA stability	ENSRNOG00000008788	0.67	0.35	blup	1512	0.45	6.3e-38	-4.8	5.1	3.4e-07	-0.80	0.29	0.71	FALSE

h2: Heritability estimate for the given transcriptomic model. PP3: Posterior probability of two distinct causal variants. PP4: Posterior probability of a single shared causal variant. joint: Whether the RNA phenotype is in the joint model.