Hub : Genes

Abca6

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Liver alternative TSS XM_006247654.5 0.29 0.08 0.0e+00 0.19 0.19 0.2 0.2 1.5e-20 1.6e-20 2.2e-21 2.7e-22
2 Liver alternative TSS XM_039087447.2 0.26 0.07 0.0e+00 0.13 0.22 0.21 0.22 5.6e-14 6.5e-24 5.1e-23 9.7e-24
3 Liver mRNA stability Abca6 0.31 0.08 0.0e+00 0.31 0.32 0.31 0.31 5.9e-35 4.9e-36 3.9e-35 3.9e-35
4 Liver isoform ratio XM_002727835.8 0.11 0.04 6.7e-16 0.12 0.12 0.14 0.12 1.6e-13 5.1e-13 2.7e-15 4.1e-13
5 Liver isoform ratio XM_039087447.2 0.22 0.08 0.0e+00 0.14 0.14 0.12 0.12 7.1e-15 1.0e-15 1.2e-13 1.2e-13
6 Liver isoform ratio XM_063270045.1 0.03 0.02 1.1e-03 0.03 0.01 0.02 0.02 5.2e-04 9.1e-03 1.9e-03 9.3e-04
7 Liver alternative TSS XM_006247655.5 0.04 0.02 6.8e-04 0.01 0.03 0.02 0.01 1.1e-02 2.7e-04 4.4e-03 9.6e-03
8 IL gene expression Abca6 0.21 0.11 6.9e-03 0.02 0.1 0.03 0.04 1.2e-01 2.8e-03 8.5e-02 4.9e-02
9 pVTA gene expression Abca6 0.04 0.02 3.7e-03 0.04 0.03 0.02 0.03 5.0e-04 2.6e-03 1.5e-02 2.0e-03
10 NAcc gene expression Abca6 0.07 0.03 4.2e-15 0.07 0.1 0.09 0.09 2.6e-11 9.5e-15 1.2e-13 6.3e-14
11 Liver alternative TSS XM_006247654.5 0.06 0.03 3.8e-06 0.03 0.05 0.04 0.03 2.1e-04 1.3e-06 2.6e-05 2.8e-04
12 Liver gene expression Abca6 0.21 0.07 0.0e+00 0.2 0.17 0.19 0.19 1.3e-21 5.7e-19 3.4e-20 6.0e-21
13 Liver intron excision ratio chr10_95709256_95710607 0.08 0.04 4.7e-07 0.05 0.06 0.04 0.04 1.7e-06 8.3e-07 1.9e-05 6.7e-05
14 Brain gene expression Abca6 0.17 0.06 0.0e+00 0.21 0.21 0.18 0.23 2.2e-19 3.6e-19 8.7e-17 2.2e-21
15 Liver isoform ratio XM_006247654.5 0.14 0.06 2.0e-11 0.1 0.08 0.08 0.08 4.8e-11 3.7e-09 6.9e-09 2.7e-09
16 Liver intron excision ratio chr10_95709256_95710743 0.22 0.07 0.0e+00 0.23 0.21 0.23 0.16 1.1e-24 9.8e-23 8.4e-26 1.7e-17
17 PL gene expression Abca6 0.11 0.04 7.6e-14 0.16 0.14 0.15 0.15 9.4e-17 7.9e-15 1.2e-15 2.0e-16
18 Liver isoform ratio XM_006247655.5 0.3 0.09 0.0e+00 0.29 0.31 0.33 0.23 7.7e-33 8.2e-35 8.6e-38 3.6e-25
19 Liver intron excision ratio chr10_95709256_95710598 0.07 0.03 1.2e-07 0.08 0.04 0.07 0.04 2.6e-09 2.4e-05 4.8e-08 6.3e-05
20 BLA gene expression Abca6 0.15 0.06 2.8e-08 0.13 0.12 0.13 0.13 2.7e-07 9.9e-07 2.8e-07 3.5e-07
21 Adipose gene expression Abca6 0.28 0.08 0.0e+00 0.26 0.28 0.31 0.32 7.3e-29 4.4e-31 2.2e-35 1.1e-35
22 IC gene expression Abca6 0.12 0.06 2.3e-04 0.11 0.11 0.08 0.12 2.4e-05 2.0e-05 4.3e-04 1.4e-05

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22
Bone: apparent density3.05.113.22.2-1.50.43.3-1.22.10.53.10.43.61.50.32.13.2-0.3-2.12.9-2.13.03.02.32.7
Area under the delay curve0.10.10.70.4-0.1-0.5-0.3-0.0-0.6-0.0-0.1-0.2-0.2-0.0-0.20.2-0.00.6-0.00.10.10.0-0.5-0.3-0.9
BMI with tail4.013.926.3-0.9-0.2-2.9-4.3-0.7-2.01.9-5.1-2.6-4.5-4.2-2.6-4.4-4.72.54.6-4.64.6-4.7-4.5-4.6-4.1
BMI without tail8.425.555.2-0.8-0.8-3.9-5.6-1.7-2.23.1-7.4-3.9-5.4-6.0-4.0-6.8-6.03.96.3-5.96.2-5.9-6.0-5.9-5.2
Body weight7.231.350.40.9-2.5-5.7-5.0-3.1-1.44.1-6.6-5.5-5.2-6.6-5.5-6.6-6.35.37.1-6.57.0-6.4-6.1-7.0-6.5
Weight adjusted by age2.43.68.1-0.6-0.1-1.5-2.2-0.2-0.90.5-1.8-1.4-2.5-1.7-1.5-1.5-2.51.42.3-2.72.2-2.6-2.3-2.5-2.8
Bone surface3.36.115.23.8-3.1-1.43.7-2.63.12.02.9-1.23.90.5-1.31.43.21.2-1.32.8-1.12.92.91.51.9
Bone volume3.15.614.33.8-3.0-1.43.5-2.62.81.92.9-1.23.70.4-1.31.43.01.3-1.22.6-0.92.72.81.31.9
Breakpoint value in progressive ratio session1.01.33.0-1.71.70.8-1.51.6-1.3-1.4-1.70.9-1.40.41.0-0.1-1.1-0.90.2-0.9-0.0-0.9-1.0-0.2-1.1
Number of licking bursts0.20.30.90.5-0.7-0.80.0-0.60.70.6-0.5-1.0-0.1-0.6-0.6-0.4-0.20.60.3-0.20.4-0.5-0.2-0.6-0.8
Context. condit. distance diff. score0.10.10.6-0.40.30.1-0.30.4-0.6-0.4-0.2-0.0-0.50.10.10.0-0.40.10.1-0.20.0-0.1-0.2-0.1-0.8
Locomotion velocity, session 10.00.00.2-0.10.1-0.0-0.3-0.0-0.30.1-0.2-0.0-0.1-0.20.0-0.2-0.20.10.2-0.10.2-0.20.0-0.30.4
Locomotion distance, session 10.50.73.4-1.00.91.2-0.70.9-1.8-0.70.71.0-0.20.31.00.4-0.3-0.8-0.1-0.0-0.1-0.10.10.31.6
Locomotion velocity, session 20.20.34.0-0.20.00.5-0.2-0.3-0.60.30.5-0.10.3-0.3-0.1-0.40.10.00.3-0.10.30.00.2-0.12.0
Locomotion distance, session 20.91.36.7-1.11.11.7-0.21.0-1.6-0.81.31.40.40.81.40.90.3-1.4-0.60.6-0.60.60.71.02.6
Locomotion velocity, session 31.31.54.1-2.01.71.5-1.41.6-1.9-0.9-0.21.8-1.10.01.8-0.0-0.9-1.80.0-0.5-0.1-0.5-0.60.21.1
Locomotion distance, session 30.60.61.8-0.20.30.60.20.6-0.7-0.61.41.20.40.71.21.10.3-1.2-0.80.7-0.90.50.70.80.7
Stereotopy head waving bouts, day 32.83.27.6-2.12.72.8-0.32.6-1.3-2.40.22.6-0.12.02.61.60.4-2.4-1.60.7-1.80.60.71.61.4
Stereotopy head waving duration, day 30.81.02.3-1.31.51.5-0.21.4-0.4-1.20.11.5-0.20.91.50.70.3-1.4-0.90.4-1.00.40.30.81.0
Locomotion velocity, session 70.40.41.1-0.00.20.70.40.4-0.5-0.50.90.70.60.60.70.80.6-0.8-0.70.7-0.70.60.90.81.0
Locomotion distance, session 70.20.21.10.4-0.50.20.4-0.2-0.80.31.10.20.80.20.20.60.4-0.3-0.20.4-0.30.40.50.40.6
Stereotopy head waving bouts, day 70.91.01.6-0.60.60.90.90.51.1-0.70.71.20.81.01.20.70.9-1.3-1.21.0-1.21.01.21.21.3
Stereotopy head waving duration, day 71.41.72.7-0.81.01.41.10.91.2-1.10.91.50.91.41.51.11.3-1.6-1.61.4-1.71.41.51.61.6
Locomotion velocity, session 80.30.40.90.2-0.1-0.3-0.6-0.2-0.90.1-0.0-0.9-0.6-0.4-0.9-0.3-0.50.90.8-0.70.7-0.6-0.8-0.90.1
Locomotion distance, session 80.40.62.9-0.80.71.1-0.40.7-1.7-0.60.90.80.00.40.90.5-0.1-0.7-0.20.2-0.30.40.40.61.4
Degree of sensitization distance0.10.10.30.1-0.2-0.0-0.1-0.3-0.20.4-0.4-0.50.1-0.4-0.5-0.4-0.10.50.5-0.30.5-0.3-0.3-0.30.2
Degree of sensitization stereotypy0.10.11.0-0.30.00.10.4-0.21.00.1-0.00.40.3-0.00.4-0.40.2-0.5-0.20.2-0.20.30.50.30.7
Conditioned locomotion0.10.20.60.3-0.6-0.20.4-0.70.40.7-0.2-0.30.8-0.4-0.3-0.40.30.40.10.30.00.30.20.10.4
Cocaine response after cond. corrected1.11.33.41.8-1.6-1.70.7-1.51.31.40.1-1.90.6-0.7-1.8-0.30.31.80.7-0.10.80.0-0.0-0.7-0.9
Cocaine response after cond. not corrected1.41.64.01.8-1.8-1.90.7-1.81.41.7-0.2-2.00.5-1.0-2.0-0.70.21.90.8-0.21.0-0.1-0.3-0.9-1.0
Cocaine response before conditioning0.10.10.3-0.50.30.1-0.30.1-0.10.3-0.60.4-0.3-0.50.3-0.5-0.2-0.40.2-0.20.3-0.3-0.4-0.20.3
Saline control response2.53.39.1-2.11.60.6-2.91.4-3.0-0.6-2.50.4-2.5-1.20.4-1.7-2.6-0.31.7-2.11.6-2.1-2.1-1.3-1.2
Bone: connectivity density2.74.311.11.0-0.51.52.7-0.40.90.12.51.23.31.61.11.92.9-1.2-2.12.5-2.12.72.62.53.3
Bone: cortical apparent density3.24.412.7-3.63.43.1-1.83.2-2.7-2.6-0.92.9-1.71.32.80.5-1.1-2.8-0.7-0.9-0.8-0.7-1.10.90.5
Bone: cortical area0.30.41.30.4-0.4-0.7-0.5-0.5-0.51.1-0.7-0.5-0.1-1.1-0.4-0.9-0.40.41.0-0.51.0-0.5-0.4-0.60.5
Bone: cortical porosity1.71.95.32.1-2.3-1.71.5-2.31.92.00.3-1.41.6-1.1-1.4-0.81.11.40.10.90.20.80.8-0.10.2
Bone: cortical porosity1.82.05.02.0-2.2-2.20.8-2.21.72.1-0.4-1.70.8-1.5-1.7-1.20.31.70.80.20.80.10.2-0.8-0.8
Bone: cortical thickness4.06.619.0-4.43.82.8-3.53.3-4.2-2.0-2.22.6-3.1-0.12.7-0.9-2.6-2.60.9-2.20.6-2.2-2.2-0.40.4
Bone: cortical thickness2.63.08.2-2.82.82.6-0.92.6-1.7-2.0-0.62.7-0.61.22.80.6-0.3-2.9-0.8-0.1-0.9-0.00.21.31.0
Bone: cortical tissue density3.14.212.2-3.53.33.1-1.83.1-2.6-2.6-0.92.8-1.71.32.80.5-1.0-2.7-0.7-0.8-0.8-0.6-1.10.90.4
Condit. Reinf. active minus inactive responses0.91.02.20.3-1.0-1.2-0.3-1.00.31.3-1.0-0.6-0.5-1.5-0.6-1.4-0.90.61.2-1.21.2-1.3-0.8-1.2-0.9
Condit. Reinf. active-inactive response ratio0.10.10.9-0.1-0.1-0.30.4-0.01.0-0.0-0.50.30.00.00.3-0.2-0.0-0.3-0.1-0.3-0.0-0.30.2-0.0-0.8
Condit. Reinf. active responses1.01.33.60.6-1.3-1.4-0.1-1.50.51.9-0.7-1.0-0.2-1.8-1.0-1.6-0.80.91.4-1.11.3-1.2-0.6-1.3-0.2
Condit. Reinf. inactive responses0.91.14.10.9-1.4-1.30.0-1.60.22.00.1-1.30.2-1.5-1.2-1.1-0.21.21.1-0.41.1-0.4-0.3-1.00.8
Incentive salience index mean0.20.20.6-0.0-0.4-0.40.1-0.50.50.6-0.5-0.0-0.1-0.7-0.0-0.8-0.4-0.10.5-0.60.5-0.7-0.0-0.4-0.2
Condit. Reinf. lever presses0.20.31.1-1.00.70.8-0.10.7-0.2-0.5-0.10.8-0.20.20.8-0.0-0.4-1.0-0.0-0.4-0.1-0.50.30.10.4
Condit. Reinf. active minus inactive responses2.43.111.22.1-3.0-2.31.1-3.21.83.30.1-1.81.4-2.3-1.8-1.90.51.91.00.11.2-0.0-0.3-1.00.5
Condit. Reinf. active-inactive response ratio2.52.99.72.3-3.0-2.31.2-3.11.93.00.4-1.91.3-1.9-1.9-1.60.71.90.80.21.00.1-0.3-0.90.0
Condit. Reinf. active responses1.82.59.12.0-2.7-1.81.1-2.81.23.00.5-1.61.6-2.0-1.5-1.40.51.60.80.51.00.20.1-0.61.1
Condit. Reinf. inactive responses0.20.22.5-0.3-0.00.4-0.1-0.1-0.70.50.10.20.5-0.50.2-0.3-0.2-0.30.20.30.30.20.30.21.6
Condit. Reinf. lever presses0.50.72.60.7-1.1-0.80.2-1.30.31.6-0.5-0.80.5-1.4-0.8-1.3-0.20.80.8-0.20.9-0.3-0.3-0.60.5
Condit. Reinf. lever reinforcers received1.52.17.71.8-2.5-1.70.9-2.50.92.80.1-1.51.3-1.9-1.5-1.50.31.50.90.31.00.1-0.1-0.70.8
Conditioned reinforcement - actives0.20.41.40.7-1.0-0.50.5-1.10.31.20.8-0.60.8-0.5-0.6-0.20.50.40.20.20.20.20.2-0.11.0
Conditioned reinforcement - inactives0.71.03.11.4-1.3-1.1-0.0-1.3-0.20.91.0-1.70.2-0.6-1.70.0-0.11.81.0-0.51.0-0.30.2-1.1-0.4
Conditioned locomotion1.41.83.50.9-1.5-1.5-0.8-1.7-0.71.8-0.4-1.4-0.5-1.9-1.4-1.4-1.11.41.7-1.41.7-1.6-1.3-1.7-0.6
Patch foraging indifference point 0 sec2.24.09.1-0.1-1.0-1.2-2.0-1.4-1.92.2-2.0-1.5-1.4-3.0-1.5-3.0-2.41.72.9-2.12.7-2.0-2.4-2.3-0.3
Patch foraging indifference point AUC0.30.41.2-0.60.4-0.0-1.00.5-1.0-0.3-0.70.1-1.1-0.40.2-0.6-0.9-0.40.5-0.70.5-0.7-0.7-0.3-0.6
Delay disc. indifference point, 0s delay0.40.41.2-0.40.50.60.10.8-0.7-0.70.41.1-0.00.71.00.80.2-1.0-1.00.4-1.00.3-0.10.6-0.4
Delay disc. indifference point, 16s delay0.50.52.00.6-0.5-1.4-0.2-0.40.70.4-1.0-1.0-0.4-0.5-1.0-0.4-0.41.40.5-0.30.6-0.3-0.3-0.8-1.2
Delay disc. indifference point, 2s delay0.10.10.60.6-0.20.1-0.10.1-0.8-0.20.60.30.20.40.40.60.2-0.2-0.30.2-0.30.3-0.10.3-0.2
Delay disc. indifference point, 24s delay0.70.85.01.2-1.3-1.61.0-1.22.21.2-0.1-0.50.7-0.6-0.6-0.40.50.90.00.40.10.30.3-0.2-0.4
Delay disc. indifference point, 4s delay0.20.21.30.50.10.0-0.50.1-1.1-0.3-0.2-0.2-0.40.1-0.20.10.20.5-0.10.2-0.10.1-0.7-0.2-0.7
Delay disc. indifference point, 8s delay0.60.72.4-0.91.20.7-1.01.3-1.6-1.1-0.51.1-0.90.51.10.5-0.4-0.7-0.4-0.2-0.4-0.2-1.00.1-1.0
Indifference point function ln k0.30.63.60.1-0.40.20.8-0.60.70.80.70.81.1-0.20.7-0.10.8-0.5-0.40.8-0.51.00.70.71.9
Indifference point function log k0.30.63.60.1-0.40.20.8-0.60.70.80.70.81.1-0.20.7-0.10.8-0.5-0.40.8-0.51.00.70.71.9
Patch foraging total patch changes 0 sec2.24.09.0-0.2-0.8-1.1-2.1-1.3-1.92.0-2.1-1.5-1.5-2.9-1.4-3.0-2.51.62.9-2.22.7-2.1-2.5-2.3-0.3
Patch foraging total patch changes 12 sec0.81.03.2-0.2-0.3-0.2-1.2-0.4-1.80.9-1.0-0.4-0.8-1.5-0.3-1.6-1.30.31.3-1.11.3-1.2-1.3-0.9-0.3
Patch foraging total patch changes 18 sec1.82.86.6-1.20.2-0.6-2.3-0.0-1.90.7-1.9-0.5-2.2-2.0-0.4-2.1-2.60.42.2-2.22.0-2.3-2.0-1.9-0.7
Patch foraging total patch changes 24 sec1.22.04.30.8-1.3-1.6-0.9-1.5-0.31.8-1.0-1.6-0.6-2.1-1.6-1.9-1.11.52.0-1.22.0-1.2-1.1-1.5-0.0
Patch foraging total patch changes 6 sec4.67.015.1-0.0-1.3-2.0-2.7-1.7-2.02.4-2.8-2.1-2.5-3.7-2.0-3.9-3.22.13.4-2.93.3-2.8-3.4-3.0-2.1
Patch foraging time to switch 0 sec0.20.52.00.9-0.3-0.10.60.10.7-0.70.6-0.20.61.0-0.31.10.60.3-0.80.6-0.70.50.70.3-1.4
Patch foraging water rate 0 sec1.53.19.0-1.1-0.2-0.6-1.7-0.8-1.41.8-2.5-0.8-1.5-2.6-0.7-3.0-2.00.82.3-2.12.2-2.1-2.3-1.80.3
Patch foraging water rate 12 sec1.22.45.0-1.91.10.3-2.20.7-2.1-0.0-2.10.1-2.1-1.20.1-1.5-2.1-0.01.8-2.21.6-2.0-2.2-1.4-0.4
Patch foraging water rate 18 sec0.40.72.4-1.20.81.30.10.6-0.2-0.20.01.40.30.41.50.00.4-1.4-0.50.3-0.70.30.00.91.5
Patch foraging water rate 24 sec0.50.73.4-1.20.91.00.20.7-0.2-0.30.31.30.20.51.40.40.3-1.3-0.40.2-0.50.30.30.71.8
Patch foraging water rate 6 sec0.50.72.7-1.61.41.1-0.71.1-1.0-0.8-1.31.1-0.60.21.0-0.4-0.5-1.10.1-0.50.0-0.5-0.50.20.5
Seeking ratio, delayed vs. immediate footshock2.83.46.6-0.6-0.3-1.7-1.7-0.6-0.11.3-2.5-1.4-2.4-2.3-1.4-2.4-2.01.31.9-2.11.9-2.1-2.6-2.2-2.2
Distance traveled before self-admin0.20.30.9-0.80.5-0.2-0.80.4-0.1-0.4-0.6-0.2-0.90.0-0.1-0.0-0.70.20.4-0.70.3-0.8-0.8-0.6-1.0
Distance traveled after self-admin0.20.20.7-0.70.5-0.1-0.60.4-0.1-0.4-0.60.0-0.7-0.0-0.0-0.1-0.6-0.10.4-0.60.2-0.5-0.4-0.3-0.8
Extensor digitorum longus weight0.62.312.9-0.90.7-0.9-2.10.9-1.1-0.7-1.5-0.4-2.6-0.6-0.4-0.4-2.00.21.0-1.80.9-1.8-2.0-1.5-3.6
Bone: elastic displacement0.60.62.3-1.51.11.2-0.40.8-0.6-0.60.21.3-0.20.31.4-0.0-0.2-1.2-0.2-0.2-0.30.10.20.51.5
Bone: elastic work0.20.20.8-0.80.40.3-0.50.2-0.40.1-0.50.5-0.2-0.40.6-0.6-0.4-0.60.4-0.40.3-0.30.00.00.9
Bone: endosteal estimation7.716.851.67.2-6.7-6.13.7-6.25.45.21.2-5.53.5-2.5-5.4-1.02.35.31.21.61.71.31.5-1.4-1.3
Bone: endosteal perimeter7.616.249.97.1-6.6-6.03.5-6.04.75.41.4-5.53.4-2.7-5.4-1.12.25.31.31.61.81.41.3-1.4-0.7
Epididymis fat weight3.010.328.6-0.40.0-2.7-3.6-0.1-1.60.8-4.8-2.6-4.1-2.7-2.5-3.2-3.92.43.5-3.73.5-3.8-4.0-3.7-5.3
Delta time in closed arm before/after self-admin1.51.43.51.1-0.60.11.8-0.41.5-0.11.50.31.41.00.31.21.9-0.3-1.41.6-1.31.51.41.20.7
Delta time in open arm before/after self-admin0.70.71.9-0.00.50.70.40.60.1-0.91.30.30.71.20.31.40.6-0.4-0.70.8-0.70.91.40.81.4
Diff in mean of infusions in LGA sessions1.11.33.5-1.91.61.2-1.61.4-1.9-0.9-1.11.0-1.40.01.1-0.2-1.0-1.10.1-0.90.1-1.0-1.4-0.1-0.9
Delay discount exponential model param0.10.20.7-0.70.40.70.20.30.4-0.20.10.40.10.10.4-0.1-0.1-0.8-0.0-0.1-0.1-0.00.50.30.9
Extinction: sum of active levers before priming0.91.06.00.3-0.6-1.80.3-0.62.40.6-1.5-1.1-0.2-0.6-1.1-0.6-0.60.90.7-0.70.6-0.6-0.0-0.9-1.7
Active lever presses in extinction session 60.20.21.1-0.00.40.50.30.50.2-0.50.40.50.70.90.41.10.3-0.5-0.30.2-0.40.10.40.50.6
Bone: final force0.30.41.51.2-0.8-0.91.0-0.71.20.60.1-0.70.90.0-0.60.20.70.60.00.50.10.40.70.1-0.1
Bone: final moment0.30.51.61.2-0.9-0.91.0-0.81.30.70.1-0.70.9-0.0-0.60.10.70.60.00.50.10.40.80.10.0
Food consumed during 24 hour testing period1.82.57.6-2.32.61.7-1.62.8-1.6-2.4-1.51.8-1.61.02.00.4-1.3-2.0-0.4-0.5-0.6-0.5-0.20.7-0.9
Glucose0.10.10.60.4-0.1-0.8-0.30.20.00.20.6-0.2-0.6-0.0-0.20.7-0.10.20.2-0.10.3-0.1-0.3-0.3-0.2
Heart weight2.03.17.71.0-1.8-2.1-0.9-2.1-0.32.8-1.0-1.8-0.8-2.7-1.8-2.3-1.11.81.9-1.32.0-1.6-1.9-2.0-0.8
Delay discount hyperbolic model param0.20.20.9-0.90.50.70.20.30.4-0.20.10.50.10.10.5-0.1-0.1-0.9-0.1-0.1-0.2-0.00.50.40.9
Intermittent access intake day 1-15 change0.10.21.0-0.2-0.10.2-0.30.0-1.0-0.20.4-0.1-0.5-0.1-0.1-0.1-0.6-0.20.4-0.90.2-0.7-0.5-0.4-0.3
Intermittent access intake escalation0.10.31.9-0.40.10.3-0.60.1-1.4-0.10.2-0.0-0.7-0.30.0-0.4-0.8-0.30.5-1.00.4-0.8-0.7-0.4-0.2
Intermittent access intake escalation 20.10.10.5-0.1-0.00.40.30.2-0.4-0.30.40.5-0.10.30.50.1-0.1-0.7-0.3-0.3-0.4-0.10.00.4-0.4
Intermitt. access day 1 inactive lever presses0.62.45.80.9-1.2-1.3-0.8-1.6-0.61.2-1.0-2.1-0.8-1.7-2.1-1.7-1.22.42.0-1.72.0-1.6-0.9-2.1-0.9
Intermitt. access day 15 inactive lever presses0.20.42.3-0.30.30.4-0.70.2-1.5-0.70.2-0.4-0.80.1-0.40.1-0.80.30.6-1.10.6-0.9-0.2-0.8-0.8
Intermitt. access escalation Index0.10.10.3-0.10.20.10.30.10.5-0.2-0.40.40.10.10.4-0.40.2-0.4-0.40.6-0.50.40.20.4-0.0
Intermittent access day 1 total infusions0.30.51.80.0-0.4-0.5-0.8-0.6-0.51.3-0.6-0.2-0.3-1.3-0.2-1.0-0.40.20.9-0.30.9-0.6-0.8-0.60.6
Intermittent access day 15 total infusions0.81.12.4-0.5-0.3-0.3-1.3-0.6-1.50.9-0.6-0.4-1.0-1.5-0.4-1.4-1.20.31.4-1.51.3-1.5-1.5-1.20.0
Intermittent access terminal intake (last 3 days)0.20.30.80.1-0.5-0.1-0.5-0.5-0.90.6-0.0-0.3-0.4-0.8-0.3-0.7-0.50.20.6-0.70.6-0.7-0.8-0.50.0
Intermittent access total infusions0.91.02.7-0.0-0.6-0.4-1.2-0.9-1.41.4-0.5-0.6-0.6-1.6-0.6-1.4-0.90.51.3-1.11.3-1.2-1.3-1.10.4
Intermittent access day 1 locomotion1.01.33.10.3-0.7-0.8-1.1-0.9-1.21.5-0.8-0.8-0.7-1.8-0.8-1.4-1.00.81.6-1.21.5-1.4-1.4-1.3-0.0
Intermittent access day 15 total locomotion0.91.63.90.4-1.1-0.6-1.1-1.4-1.71.7-0.2-0.9-0.7-2.0-0.9-1.8-1.10.91.6-1.31.6-1.5-1.6-1.40.3
Intermittent access total locomotion2.12.66.5-0.0-0.9-0.8-1.8-1.2-2.11.9-1.0-0.9-1.3-2.5-0.9-2.3-1.70.92.1-1.72.0-2.0-2.1-1.8-0.0
Intermittent access standard deviation0.51.02.70.1-0.8-0.7-0.9-0.8-1.21.00.4-0.8-0.9-1.2-0.7-0.6-1.10.51.2-1.51.2-1.6-1.2-1.5-0.6
Left kidney weight0.31.32.4-0.20.0-0.4-1.6-0.2-1.50.5-1.5-0.6-1.2-1.3-0.6-1.4-1.30.61.4-1.41.4-1.4-1.5-1.2-0.8
Right kidney weight0.21.13.9-0.50.70.0-1.40.7-1.6-0.3-2.0-0.2-1.3-0.6-0.2-1.0-1.30.11.0-1.20.9-1.3-1.4-0.8-1.1
Cocaine induced anxiety0.40.51.71.0-1.3-0.61.0-1.30.71.21.0-0.70.8-0.3-0.70.20.60.70.0-0.20.1-0.2-0.0-0.40.1
Post-drug Anxiety0.20.21.4-0.0-0.20.50.7-0.2-0.30.21.20.30.70.40.30.80.5-0.4-0.50.0-0.40.10.20.30.6
Baseline Anxiety1.01.23.2-1.41.71.5-0.61.8-0.9-1.7-0.41.5-0.41.11.50.7-0.3-1.6-0.60.0-0.80.20.31.00.2
Tail length3.413.128.80.8-2.0-3.4-2.9-2.7-0.73.3-4.9-3.8-2.6-4.7-3.8-5.4-3.53.84.5-3.74.4-3.5-3.6-4.1-3.4
Length with tail2.410.616.61.5-2.3-3.5-2.3-2.6-0.52.7-3.2-3.9-2.3-3.8-3.9-3.7-3.23.94.1-3.54.0-3.3-3.0-4.0-3.9
Length without tail0.20.84.00.8-0.6-1.1-0.5-0.2-0.5-0.0-0.0-1.1-0.8-0.3-1.00.2-1.01.00.9-1.20.9-1.0-0.5-1.1-2.0
Times rat made contact with spout0.50.61.5-0.20.10.1-1.0-0.1-1.20.3-1.0-0.5-1.0-0.9-0.3-1.2-0.90.30.8-0.90.8-1.0-1.2-0.80.2
Lifetime Intake0.81.02.5-0.2-0.4-0.3-1.3-0.8-1.41.3-0.5-0.5-0.5-1.6-0.5-1.3-1.00.51.4-1.11.4-1.2-1.1-1.10.7
Liver weight, left0.91.64.12.0-1.9-1.60.3-2.00.62.0-0.5-1.70.7-1.5-1.7-1.40.31.61.0-0.01.1-0.0-0.3-0.70.4
Liver weight, right0.30.52.1-0.71.00.3-1.20.8-1.0-0.8-1.40.5-1.00.00.5-0.4-0.7-0.50.2-0.50.2-0.6-0.5-0.1-1.0
Locomotor activity0.40.62.1-0.1-0.3-1.0-0.5-0.50.51.3-1.30.0-0.5-1.40.0-1.4-0.6-0.11.0-0.70.9-0.7-0.8-0.5-0.1
Locomotor testing distance1.11.94.6-0.8-0.1-1.0-1.3-0.5-0.41.6-1.9-0.1-1.4-2.2-0.1-2.1-1.60.11.8-1.81.8-1.9-1.7-1.4-0.1
Locomotor testing rearing2.85.511.2-1.50.3-1.0-2.8-0.4-1.71.6-3.3-0.6-2.8-3.0-0.6-3.3-3.00.52.9-3.12.8-3.3-3.3-2.6-1.3
Locomotion in novel chamber0.30.41.70.80.0-0.90.30.11.3-0.7-0.0-0.9-0.10.8-0.90.90.30.9-0.10.1-0.00.10.5-0.3-0.9
Locomotion in novel chamber post-restriction0.81.32.7-0.00.70.90.90.90.3-1.40.91.00.81.61.11.41.2-0.8-1.41.4-1.51.51.41.50.8
Fecal boli incidents, locomotor time 10.71.04.81.2-0.90.11.3-0.40.30.12.20.21.40.70.21.31.3-0.2-1.01.3-1.01.20.91.00.6
Change in fecal boli incidents, locomotor task0.60.61.7-1.01.00.60.11.20.4-1.30.01.0-0.11.11.00.8-0.0-0.9-0.70.3-0.80.10.70.5-0.6
Time >=10cm from walls, locomotor time 10.20.20.7-0.40.40.60.10.50.1-0.40.70.50.40.50.50.90.2-0.4-0.30.4-0.30.30.30.40.6
Bouts of movement, locomotor time 10.50.61.5-0.40.0-0.1-1.0-0.2-1.10.4-0.9-0.6-1.0-0.9-0.7-1.2-0.90.60.7-0.60.7-0.8-1.2-0.8-0.9
Total resting periods, locomotor time 10.20.30.6-0.1-0.1-0.1-0.5-0.2-0.70.3-0.5-0.5-0.6-0.6-0.6-0.8-0.50.50.3-0.30.4-0.5-0.8-0.5-0.8
Rest time, locomotor task time 10.10.10.50.0-0.00.20.10.2-0.3-0.20.70.6-0.10.40.60.60.2-0.5-0.70.2-0.6-0.1-0.10.2-0.1
Distance moved, locomotor task time 10.40.62.0-0.81.00.2-1.30.8-0.5-0.8-1.4-0.2-1.2-0.1-0.2-0.5-0.9-0.10.6-0.80.7-0.7-0.8-0.4-0.8
Vertical activity count, locomotor time 10.30.73.1-1.01.10.3-1.20.8-0.6-0.6-1.80.0-1.3-0.3-0.0-0.7-1.1-0.20.7-1.00.6-0.8-0.9-0.4-0.8
Time >=10cm from walls, locomotor time 20.81.22.8-1.71.60.6-1.31.5-0.9-1.3-1.21.2-1.40.31.10.0-1.3-1.20.2-1.00.0-1.0-0.7-0.2-1.3
Bouts of movement, locomotor time 20.81.44.4-1.51.40.5-2.01.5-2.1-1.3-1.20.3-1.8-0.10.3-0.3-1.6-0.20.6-0.80.4-0.9-1.1-0.6-1.3
Total resting periods, locomotor time 20.61.14.5-1.31.30.6-1.81.4-2.1-1.3-0.70.4-1.70.10.4-0.0-1.3-0.40.5-0.60.3-0.7-0.9-0.5-1.1
Rest time, locomotor task time 21.72.26.01.1-0.40.31.70.11.0-0.72.50.41.41.70.42.22.1-0.5-2.02.3-1.91.81.41.50.9
Distance moved, locomotor task time 22.22.68.3-2.32.31.1-2.31.8-1.6-1.5-2.90.8-2.1-0.20.8-1.1-2.0-0.70.8-1.90.8-1.7-1.6-0.9-1.4
Vertical activity count, locomotor time 21.62.29.0-1.81.50.7-2.01.0-1.5-0.4-3.00.3-1.8-0.90.3-1.8-2.0-0.31.3-2.01.2-1.7-1.6-1.0-0.9
Light reinforcement 10.92.26.6-2.42.11.8-1.32.2-1.8-1.4-0.72.5-0.80.52.60.2-0.7-2.5-0.5-0.1-0.6-0.1-0.11.00.3
Light reinforcement 20.10.11.1-0.10.1-0.60.30.21.0-0.00.00.10.00.10.20.40.20.1-0.00.1-0.00.20.50.0-0.4
Bone: marrow area7.416.149.67.0-6.5-6.03.7-6.05.35.11.1-5.43.4-2.4-5.3-1.02.35.21.21.51.61.31.5-1.3-1.4
Bone: maximum diameter2.24.014.23.8-3.1-2.62.5-2.62.72.31.5-2.02.5-0.6-1.90.52.01.8-0.21.80.01.71.60.30.4
Bone: maximum force0.61.03.51.9-1.6-1.51.2-1.31.41.50.4-1.21.2-0.5-1.10.10.81.10.40.50.50.40.7-0.20.2
Bone: maximum moment0.61.13.41.8-1.6-1.51.2-1.41.41.50.4-1.21.2-0.6-1.1-0.00.81.10.40.40.50.30.7-0.20.2
Mean time between licks in bursts0.30.94.10.4-0.6-1.2-0.5-0.40.10.4-0.6-0.8-0.8-0.7-1.0-0.5-1.01.01.0-1.20.9-1.2-0.7-1.3-2.0
Mean num. licks in bursts0.20.32.0-0.70.80.9-0.60.7-1.4-0.5-0.00.6-0.40.10.6-0.1-0.3-0.50.1-0.2-0.0-0.0-0.50.21.1
Cd content in liver0.60.71.80.00.40.50.80.50.4-0.91.10.70.51.30.71.30.8-0.6-1.20.8-1.20.70.80.8-0.2
Co content in liver0.10.10.50.5-0.3-0.30.3-0.30.1-0.10.3-0.4-0.10.1-0.40.00.40.2-0.40.5-0.30.40.10.1-0.7
Cu content in liver0.30.41.11.1-1.0-0.60.8-0.80.90.50.9-0.50.80.1-0.50.30.80.5-0.30.5-0.20.50.40.10.2
Fe content in liver0.20.20.70.3-0.7-0.40.4-0.90.60.70.6-0.20.5-0.4-0.2-0.30.10.60.00.10.00.10.6-0.30.1
K content in liver0.90.92.60.7-0.10.71.2-0.00.4-0.30.90.11.40.90.10.81.3-0.2-0.91.3-0.81.31.31.11.6
Mg content in liver3.13.25.90.40.51.61.90.60.5-1.11.71.32.12.01.31.82.4-1.3-2.22.4-2.22.42.12.42.4
Mn content in liver4.44.89.6-0.61.22.41.91.30.1-1.42.12.52.12.22.52.22.3-2.4-2.62.6-2.72.52.42.83.1
Na content in liver0.80.92.1-0.20.71.20.50.9-0.3-1.21.30.90.61.40.91.40.7-0.9-1.00.9-1.10.80.81.01.0
Rb content in liver0.50.61.3-0.81.01.10.11.0-0.5-1.10.41.0-0.11.11.00.90.4-0.9-0.90.3-0.90.20.30.60.3
Se content in liver0.30.30.7-0.60.70.70.10.7-0.2-0.50.50.80.30.60.80.80.2-0.6-0.50.5-0.60.50.80.50.8
Sr content in liver0.10.10.40.6-0.6-0.6-0.1-0.40.00.30.2-0.3-0.2-0.4-0.3-0.3-0.20.40.30.00.30.0-0.3-0.3-0.5
Zn content in liver1.21.33.21.6-1.4-0.61.6-1.31.51.01.5-0.51.80.1-0.50.51.50.5-0.61.3-0.41.31.20.71.5
Bone: minimum diameter5.510.029.55.4-5.2-4.92.3-4.83.44.60.6-4.32.4-2.5-4.2-1.31.44.21.40.81.80.70.7-1.4-0.6
Time in familiar zone, hab. session 10.50.51.11.0-0.8-0.81.0-0.40.90.10.9-0.30.60.4-0.30.70.60.2-0.50.9-0.60.90.70.5-0.6
Time in novel zone, hab. session 10.50.51.2-1.10.71.0-0.90.4-1.1-0.1-0.80.5-0.3-0.40.5-0.7-0.6-0.50.5-0.80.5-0.7-0.7-0.10.9
Total zone transitions, hab. session 10.30.51.3-0.90.50.4-1.00.3-1.20.0-0.70.1-0.7-0.60.1-0.8-1.0-0.20.9-0.90.8-0.8-0.7-0.50.2
Total locomotion distance, hab. session 10.81.24.4-1.61.21.0-1.70.9-2.1-0.5-1.20.8-1.2-0.50.9-0.9-1.4-0.60.7-1.00.6-1.2-1.1-0.50.1
Locomotion velocity, hab. session 10.71.13.1-1.41.10.7-1.60.8-1.8-0.4-1.40.6-1.3-0.60.7-1.0-1.4-0.40.8-1.10.6-1.2-1.2-0.7-0.1
Time in familiar zone, hab. session 21.31.43.10.9-1.5-1.80.0-1.61.01.6-0.7-1.5-0.0-1.4-1.5-1.2-0.51.51.1-0.71.2-0.7-0.7-1.2-1.2
Time in novel zone, hab. session 23.63.76.4-1.01.82.50.82.0-0.7-2.11.42.31.02.32.42.11.4-2.2-2.21.8-2.21.81.82.42.1
Total zone transitions, hab. session 20.10.20.7-0.90.60.3-0.50.4-0.3-0.3-0.20.4-0.4-0.10.5-0.1-0.5-0.40.4-0.30.3-0.30.2-0.10.6
Total locomotion distance, hab. session 21.21.54.7-2.21.91.3-1.41.8-1.6-1.4-0.81.7-1.30.31.7-0.0-1.2-1.60.0-0.6-0.1-0.7-0.30.10.2
Locomotion velocity, hab. session 21.21.64.7-2.22.01.4-1.41.9-1.7-1.4-0.81.7-1.30.41.70.1-1.1-1.6-0.1-0.5-0.2-0.6-0.30.20.3
Novel to familiar place preference ratio3.33.67.82.0-2.5-2.50.2-2.61.42.5-0.4-2.80.1-2.1-2.8-1.9-0.52.82.0-1.12.1-0.9-0.9-1.8-0.4
Novelty place preference2.62.86.31.9-2.3-2.30.3-2.41.42.3-0.1-2.50.1-1.8-2.5-1.6-0.32.51.7-0.91.8-0.7-0.8-1.6-0.2
Time in novel zone, NPP test2.32.45.31.7-2.1-2.10.3-2.31.32.1-0.1-2.30.2-1.7-2.3-1.6-0.32.31.6-0.81.7-0.6-0.7-1.4-0.1
Total zone transitions, NPP test0.71.03.4-1.51.41.4-0.61.2-1.2-0.80.21.4-0.20.41.40.3-0.2-1.5-0.30.3-0.40.20.60.71.8
Total locomotion distance, NPP test1.72.46.3-2.52.32.3-1.22.0-2.3-1.5-0.52.4-0.60.72.30.2-0.6-2.3-0.50.0-0.7-0.20.10.91.6
Locomotion velocity, NPP test1.62.26.7-2.52.32.1-1.62.0-2.6-1.4-0.72.1-1.10.42.10.0-1.0-2.1-0.1-0.4-0.3-0.6-0.30.51.2
Intraocular pressure2.84.19.20.7-1.8-2.3-1.2-2.20.12.9-1.3-2.1-0.9-3.0-2.1-2.4-1.82.22.7-1.92.7-2.0-1.7-2.6-0.5
Delta distance traveled before/after self-admin0.20.20.8-0.60.50.40.10.40.3-0.2-0.20.90.10.00.8-0.20.1-0.9-0.20.2-0.30.30.40.50.3
Delta ambulatory time before/after self-admin0.50.61.20.2-0.00.41.00.20.8-0.10.61.00.90.50.90.40.7-1.1-0.90.8-0.90.91.11.10.5
Parametrial fat weight1.02.44.40.90.10.62.10.51.6-1.11.40.91.82.00.92.02.0-0.8-2.12.0-2.01.92.11.90.5
Pavlov. Cond. lever latency1.72.25.00.50.20.91.50.50.2-0.92.00.71.51.80.72.11.9-0.8-1.82.1-1.72.21.61.91.2
Pavlov. Cond. magazine entry latency0.40.52.0-0.90.50.2-0.60.3-0.30.0-1.40.3-0.6-0.50.2-0.9-0.9-0.10.7-1.10.6-1.1-0.6-0.6-1.0
Pavlov. Cond. change in total contacts1.51.64.0-0.0-0.6-0.9-0.9-0.9-0.01.1-1.8-1.0-0.9-1.6-1.0-2.0-1.41.11.7-1.71.6-1.7-1.1-1.6-1.1
Pavlov. Cond. index score0.81.02.7-0.5-0.1-0.5-0.9-0.2-0.10.6-1.6-0.4-0.9-1.1-0.4-1.4-1.30.51.3-1.61.1-1.6-1.0-1.2-1.2
Pavlov. Cond. latency score1.01.33.1-0.5-0.0-0.5-1.1-0.2-0.30.5-1.8-0.5-1.1-1.2-0.5-1.5-1.50.61.4-1.71.3-1.8-1.2-1.4-1.3
Pavlov. Cond. lever contacts1.11.33.1-0.5-0.1-0.6-1.2-0.3-0.30.7-1.6-0.5-1.2-1.3-0.5-1.6-1.50.61.4-1.71.3-1.8-1.3-1.5-1.0
Pavlov. Cond. magazine entry number0.30.31.20.5-0.20.00.5-0.10.1-0.11.1-0.10.50.4-0.00.70.8-0.0-0.61.0-0.51.00.50.51.1
Pavlov. Cond. intertrial magazine entries4.65.512.82.3-3.2-3.4-0.2-3.41.13.6-0.3-3.0-0.0-3.1-3.0-2.3-0.93.02.5-1.32.6-1.2-1.0-2.5-0.5
Pavlov. Cond. lever-magazine prob. diff.0.60.71.8-0.4-0.1-0.3-0.7-0.2-0.10.5-1.3-0.2-0.6-0.9-0.3-1.2-1.10.31.1-1.41.0-1.3-0.8-1.0-0.8
Pavlov. Cond. response bias0.30.31.4-0.4-0.0-0.2-0.3-0.20.30.5-1.2-0.0-0.3-0.6-0.1-1.0-0.60.10.6-0.90.5-0.9-0.5-0.6-0.7
Pavlov. Cond. lever latency0.50.62.5-0.91.10.4-0.91.2-0.5-1.3-0.70.4-1.30.50.40.3-0.8-0.4-0.0-0.6-0.1-0.7-0.8-0.2-1.6
Pavlov. Cond. magazine entry latency0.10.10.70.2-0.2-0.70.1-0.10.60.20.4-0.3-0.2-0.1-0.20.3-0.10.20.2-0.30.2-0.00.4-0.3-0.8
Pavlov. Cond. change in total contacts0.30.41.80.6-1.1-0.80.6-1.10.71.30.4-0.50.7-0.8-0.6-0.40.20.70.5-0.00.50.00.5-0.40.6
Pavlov. Cond. index score0.60.82.31.2-1.4-1.21.0-1.41.21.50.7-0.81.0-0.7-0.8-0.20.60.80.20.40.40.50.8-0.20.4
Pavlov. Cond. latency score0.50.72.31.1-1.4-1.20.8-1.31.21.50.6-0.80.8-0.8-0.8-0.30.40.80.40.30.40.40.7-0.30.4
Pavlov. Cond. lever contacts0.40.53.00.6-0.80.00.9-0.80.30.90.80.01.3-0.3-0.0-0.10.80.0-0.30.8-0.20.90.90.51.7
Pavlov. Cond. magazine entry number0.10.10.60.10.20.80.00.1-0.5-0.4-0.40.10.30.30.1-0.20.3-0.1-0.30.3-0.30.2-0.20.40.6
Pavlov. Cond. intertrial magazine entries0.60.92.30.50.10.71.20.30.7-0.50.50.61.41.00.60.81.2-0.6-1.21.5-1.11.41.11.41.2
Pavlov. Cond. lever-magazine prob. diff.0.50.72.11.1-1.3-1.20.9-1.31.11.40.7-0.80.9-0.7-0.8-0.20.50.80.30.30.30.40.7-0.20.3
Pavlov. Cond. response bias0.50.61.80.9-1.0-0.31.0-1.00.51.01.0-0.21.3-0.2-0.20.10.90.2-0.30.8-0.20.91.00.51.3
Time in closed arm before self-admin0.70.94.2-0.90.3-0.4-1.20.0-0.20.7-2.00.2-1.1-1.40.2-1.8-1.3-0.21.0-1.00.9-1.0-0.9-0.7-0.5
Time in closed arm after self-admin0.50.52.1-0.40.1-0.6-0.7-0.10.10.5-1.40.1-1.0-0.90.0-1.1-0.7-0.10.6-0.80.6-0.8-0.7-0.6-1.1
Time in open arm before self-admin0.60.73.8-0.60.4-0.2-1.00.6-1.0-0.6-0.2-0.1-1.20.0-0.10.2-1.00.10.6-1.20.5-1.2-1.1-0.9-1.9
Time in open arm after self-admin0.20.20.80.3-0.4-0.6-0.3-0.2-0.20.00.6-0.9-0.1-0.1-0.80.4-0.50.80.6-0.50.6-0.4-0.1-0.7-0.4
Bone: periosteal estimation4.28.826.75.2-4.8-4.52.5-4.53.54.20.5-4.02.5-2.2-3.8-1.11.53.81.21.01.60.81.0-1.1-0.5
Bone: periosteal perimeter3.45.818.14.3-4.0-3.81.6-3.62.13.50.7-3.41.5-2.0-3.3-0.80.93.21.20.61.40.40.3-1.2-0.5
Bone: post-yield work1.01.55.52.4-2.0-1.71.2-1.71.21.60.9-1.71.2-0.6-1.60.20.71.50.40.50.70.30.6-0.40.2
Progressive ratio test 1 active lever presses3.13.98.5-1.40.5-0.2-2.9-0.0-2.71.0-2.6-0.5-2.4-2.4-0.5-2.6-2.50.52.3-2.42.2-2.6-2.8-2.0-0.8
Progressive ratio test 1 breakpoint2.83.57.5-1.30.5-0.2-2.7-0.0-2.51.0-2.6-0.5-2.2-2.3-0.5-2.5-2.30.52.2-2.22.0-2.4-2.7-1.8-0.7
Progressive ratio test 1 inactive lever presses0.71.04.4-0.70.60.4-1.40.3-2.1-0.1-1.0-0.3-1.3-0.9-0.2-1.1-1.20.51.3-1.31.2-1.2-0.8-1.00.4
Progressive ratio test 2 active lever presses1.82.13.9-0.5-0.3-0.7-2.0-0.7-1.61.2-1.3-0.9-1.4-1.9-0.9-1.8-1.60.81.9-1.91.8-2.0-2.0-1.8-0.6
Progressive ratio test 2 breakpoint1.92.24.0-0.5-0.3-0.7-2.0-0.8-1.71.2-1.3-0.9-1.5-1.9-0.9-1.8-1.70.91.9-1.91.9-2.0-2.0-1.8-0.7
Progressive ratio test 2 inactive lever presses0.50.91.7-0.1-0.3-0.4-1.2-0.6-1.20.9-0.6-0.7-0.8-1.2-0.7-1.0-0.90.81.3-1.31.3-1.3-1.0-1.2-0.2
Incentive Sensitization - Responses0.50.81.40.8-1.0-1.1-0.8-1.0-0.50.90.1-1.2-0.4-0.9-1.2-0.5-0.61.21.0-0.71.0-0.7-0.8-1.1-0.8
Incentive Sensitization - Breakpoint0.60.71.40.8-1.0-1.1-0.7-1.0-0.50.90.2-1.2-0.4-0.9-1.2-0.5-0.51.10.9-0.61.0-0.7-0.7-1.1-0.8
Sum of active levers in priming session hrs 5-60.30.31.4-0.70.7-0.2-0.70.6-0.2-0.5-1.20.3-1.0-0.10.2-0.4-0.6-0.20.2-0.40.0-0.4-0.5-0.3-0.8
Progressive ratio0.50.93.71.3-1.1-1.70.8-0.81.90.40.6-1.30.50.2-1.30.80.21.10.30.00.40.20.5-0.5-1.2
Food seeking constrained by brief footshock0.60.72.01.1-1.1-1.11.0-1.21.30.80.2-1.40.6-0.3-1.4-0.30.31.00.5-0.30.6-0.00.9-0.5-0.7
Seeking ratio, punishment vs. effort0.20.31.5-0.40.10.6-0.4-0.2-0.90.4-0.60.1-0.4-0.80.0-1.2-0.4-0.00.4-0.50.4-0.4-0.3-0.20.4
Retroperitoneal fat weight1.25.312.5-1.30.8-0.8-2.80.6-1.9-0.2-3.4-1.2-3.2-1.7-1.2-2.4-3.21.22.4-3.12.4-3.1-2.7-2.6-3.5
Reaction time number correct0.61.22.50.10.10.11.30.41.5-0.11.01.11.10.91.11.31.3-1.1-1.41.6-1.41.51.11.40.9
Reaction time mean minus median0.30.81.80.00.60.40.71.01.2-1.3-0.00.80.21.30.81.10.5-0.8-1.30.8-1.20.60.81.0-1.0
Reaction time mean minus median AUC1.02.44.50.20.60.91.71.11.7-1.30.91.51.52.01.41.81.6-1.5-2.11.9-2.01.72.02.10.6
Reaction time num false alarms1.01.44.81.7-2.0-2.20.4-1.91.32.00.4-1.30.7-1.3-1.2-0.60.11.20.90.11.00.20.2-0.6-0.4
Reaction time num false alarms AUC0.91.44.12.0-1.9-1.81.2-1.61.91.61.0-0.81.5-0.5-0.70.20.90.80.01.00.11.11.00.30.2
Reaction time trials correct on left0.61.22.50.10.10.11.30.41.5-0.11.01.11.10.91.11.31.3-1.1-1.41.6-1.41.51.11.40.9
Reaction time trials on left0.71.42.80.20.10.21.40.41.5-0.21.11.21.21.01.21.41.4-1.1-1.51.7-1.51.61.21.50.9
Reaction time mean0.30.51.0-0.40.80.90.60.80.7-1.0-0.10.70.21.00.70.50.5-0.7-1.00.4-0.90.30.60.8-0.2
Reaction time mean AUC0.30.51.1-0.70.91.10.40.90.5-1.1-0.30.70.11.00.80.40.4-0.8-0.90.3-0.80.20.40.7-0.2
Median of all reaction times0.30.41.1-0.60.81.10.50.70.5-0.8-0.10.60.20.80.60.30.5-0.6-0.80.3-0.80.20.50.70.1
Reaction time omissions1.92.75.3-0.41.21.61.41.61.0-1.90.61.91.42.31.81.91.4-1.9-2.21.6-2.11.51.92.20.4
Reaction time false alarm rate0.81.12.91.5-1.7-1.70.2-1.60.71.50.2-1.40.5-1.1-1.4-0.7-0.11.41.0-0.31.1-0.10.0-0.7-0.6
Reaction time premature initiation rate1.11.53.40.4-0.5-0.8-1.5-0.6-1.80.6-0.6-1.0-1.3-1.3-1.0-1.2-1.31.21.6-1.41.6-1.2-1.7-1.4-1.0
Reaction time premature initiations0.10.10.50.5-0.4-0.4-0.3-0.3-0.70.30.2-0.2-0.2-0.4-0.2-0.1-0.20.30.4-0.00.4-0.0-0.5-0.2-0.0
Std. dev. reaction times1.01.84.1-0.10.91.21.31.21.1-1.60.71.20.92.01.31.71.3-1.3-1.91.4-1.81.31.51.70.1
Reaction time trials completed0.71.42.80.20.10.21.40.41.5-0.21.11.21.21.01.21.41.4-1.1-1.51.7-1.51.61.21.50.9
Reaction time trials AUC0.61.22.40.10.20.21.20.51.4-0.30.91.21.11.11.21.41.3-1.1-1.41.6-1.51.41.11.40.8
Run reversals in cocaine runway, females2.12.19.9-1.20.9-0.2-2.10.9-1.2-1.0-1.6-0.3-2.2-0.3-0.3-0.6-2.20.51.1-1.90.9-1.9-1.6-1.5-3.1
Run reversals in cocaine runway, males1.31.34.91.4-1.3-1.30.3-1.40.91.2-0.2-2.10.0-0.8-2.2-0.70.32.10.8-0.30.9-0.3-0.6-1.1-0.9
Latency to leave start box in cocaine runway2.52.86.9-2.62.41.3-2.62.1-2.2-1.5-2.61.5-2.4-0.31.4-1.0-1.8-1.10.4-1.20.3-1.3-1.8-0.4-1.0
Latency to leave start box in cocaine runway, F4.14.712.8-2.51.80.6-3.41.5-3.6-0.7-2.70.3-3.3-1.30.3-1.8-3.00.11.8-2.61.7-2.6-2.7-1.9-1.6
Latency to leave start box in cocaine runway, M2.52.45.8-1.62.01.70.12.00.7-2.0-0.72.40.11.52.30.70.7-2.4-1.71.2-1.81.20.91.80.3
Std. dev. time between licks in bursts0.50.71.7-1.21.31.0-0.81.2-1.1-1.3-0.21.2-0.80.61.10.4-0.5-1.1-0.3-0.3-0.5-0.6-0.20.1-0.3
Total sessions with >9 infusions1.41.74.7-1.10.5-0.1-2.20.1-2.10.4-1.2-0.1-1.5-1.4-0.1-1.2-1.90.11.7-1.81.6-1.8-1.3-1.40.1
Short access day 1 total inactive lever presses0.71.02.2-0.0-0.4-0.4-1.3-0.6-1.50.9-0.3-0.8-0.8-1.2-0.8-0.9-1.10.81.4-1.31.4-1.3-1.0-1.30.2
Short access day 10 total inactive lever presses0.20.42.41.0-0.4-0.51.1-0.31.5-0.10.5-0.50.60.6-0.50.70.80.5-0.40.5-0.30.61.00.20.0
Short access day 1 total infusions1.41.84.4-1.40.3-0.3-2.1-0.1-1.70.8-1.2-0.3-1.4-1.6-0.2-1.4-2.00.21.9-1.91.7-1.9-1.3-1.50.4
Short access day 10 total infusions0.70.92.4-0.30.1-0.2-1.5-0.2-1.50.7-0.9-0.4-0.9-1.3-0.4-1.2-1.10.41.4-1.01.4-1.0-0.9-0.90.7
Short access total infusions0.60.82.1-0.4-0.3-0.3-1.2-0.6-1.11.1-0.6-0.4-0.5-1.4-0.4-1.2-1.00.51.4-1.01.3-1.0-0.7-0.91.0
Short access day 1 locomotion4.05.09.9-1.20.3-0.7-3.2-0.2-2.91.0-2.7-1.1-2.6-2.5-1.1-2.7-3.01.12.9-2.92.9-3.0-2.7-2.5-0.9
Short access day 10 total locomotion0.61.23.40.3-0.9-1.1-0.8-1.0-0.31.6-1.1-0.8-0.8-1.8-0.8-1.7-0.90.61.3-1.11.3-1.1-1.4-1.1-0.4
Short access total locomotion2.32.86.6-0.90.2-0.3-2.5-0.1-2.60.8-1.8-0.5-1.9-1.9-0.5-1.8-2.20.52.2-2.22.0-2.2-2.2-1.8-0.4
One hour access (0.3 mA shock)0.30.41.00.6-0.9-0.4-0.2-0.9-0.61.00.4-0.70.2-0.8-0.7-0.5-0.30.70.7-0.40.8-0.4-0.1-0.50.7
Compulsive drug intake0.50.61.81.3-1.1-0.51.0-0.91.00.80.6-0.91.0-0.2-1.0-0.10.60.80.20.30.20.50.60.00.6
One hour access (shock baseline)0.00.10.6-0.20.10.1-0.50.0-0.80.10.10.2-0.1-0.10.20.1-0.2-0.10.1-0.20.1-0.3-0.2-0.20.2
Social response proportion0.70.82.01.1-0.6-0.31.4-0.31.3-0.10.9-0.41.41.0-0.31.31.00.5-0.81.0-0.80.91.30.6-0.3
Social responses0.40.61.0-0.40.50.90.20.7-0.5-0.80.80.90.70.91.01.00.3-0.8-0.70.7-0.80.70.90.90.5
Social time1.21.63.91.8-1.2-0.81.9-0.82.00.41.6-0.51.60.8-0.51.41.60.6-1.11.6-1.11.51.60.80.0
Soleus weight0.51.45.02.0-1.8-2.21.1-1.52.21.40.4-1.30.6-0.6-1.30.00.61.10.10.60.20.50.3-0.3-1.1
Bone: stiffness0.40.62.51.6-0.8-0.81.1-0.51.00.40.4-0.71.00.4-0.80.80.90.7-0.20.8-0.10.70.80.3-0.4
Tibialis anterior weight0.41.47.10.2-0.3-1.4-1.0-0.30.10.4-1.8-1.1-1.2-1.1-1.1-1.1-1.21.01.2-1.21.1-1.0-1.2-1.2-2.7
Time to tail flick, vehicle, before self-admin0.20.20.70.7-0.6-0.10.1-0.6-0.40.30.6-0.8-0.1-0.0-0.90.30.20.90.1-0.30.3-0.0-0.3-0.5-0.3
Time to tail flick, vehicle, after self-admin0.40.61.71.3-1.1-1.20.9-0.81.30.51.1-0.70.70.2-0.70.80.80.6-0.30.5-0.10.30.6-0.1-0.6
Time to tail flick, test, before self-admin2.42.56.72.3-2.6-2.20.9-2.61.52.20.0-2.20.8-1.5-2.1-1.30.52.30.70.30.80.2-0.0-0.8-1.2
Time to tail flick, test, after self-admin0.30.30.90.9-0.7-0.10.5-0.6-0.10.40.9-0.50.80.1-0.40.40.50.5-0.10.5-0.10.40.50.20.6
Delta time to tail flick, vehicle, before/after SA0.80.81.70.7-0.10.31.00.30.3-0.61.20.41.11.10.41.21.1-0.5-1.11.3-1.01.01.21.10.7
Delta time to tail flick, test, before/after SA0.30.31.6-0.10.20.60.40.3-0.3-0.41.20.40.50.70.41.00.3-0.6-0.40.4-0.40.30.40.41.3
Tibia length1.74.88.10.3-1.0-2.0-2.0-1.3-0.81.4-2.3-2.2-2.1-2.4-2.2-2.5-2.31.92.7-2.72.7-2.8-2.5-2.8-2.8
Ambulatory time before self-admin0.40.61.6-1.11.00.1-1.10.9-0.6-1.0-1.00.0-1.30.30.10.1-0.90.10.3-0.90.2-0.9-0.9-0.6-1.2
Ambulatory time after self-admin0.30.31.0-0.90.90.2-0.20.90.3-1.0-0.60.6-0.50.60.60.2-0.3-0.6-0.2-0.2-0.4-0.20.20.1-0.9
Bone: tissue strength1.31.33.1-1.41.31.7-0.31.3-1.1-1.21.11.7-0.11.01.71.0-0.0-1.7-0.70.2-0.80.20.30.91.7
Total heroin consumption0.70.81.70.00.80.90.41.00.1-1.20.30.90.51.31.01.20.8-1.0-1.10.9-1.20.80.71.10.4
Bone: trabecular number3.25.312.41.2-0.51.53.0-0.21.3-0.33.01.33.52.11.22.43.1-1.2-2.52.9-2.43.03.02.83.3
Bone: trabecular spacing2.53.38.4-1.20.8-0.8-2.50.4-1.4-0.1-2.5-0.7-2.9-1.5-0.7-1.9-2.50.91.8-2.31.7-2.5-2.5-2.2-2.2
Bone: trabecular thickness1.62.05.12.2-1.8-0.82.0-1.61.71.41.5-0.42.20.0-0.50.61.90.5-0.71.6-0.61.71.41.01.3
Bone: trabecular tissue density0.91.43.1-1.81.60.8-1.61.6-1.4-1.2-1.01.1-1.80.21.2-0.0-1.2-1.10.0-1.0-0.1-1.2-1.4-0.4-1.3
Water consumed over 24 hours2.43.28.4-2.42.72.5-0.92.8-1.4-2.6-0.32.5-0.81.62.91.0-0.4-2.9-1.20.2-1.40.10.31.50.8
Number of responses in last shaping day1.01.12.7-1.30.70.2-1.60.3-1.5-0.1-0.8-0.0-1.5-0.70.0-0.7-1.4-0.11.1-1.71.0-1.6-1.2-1.1-0.3