Abca6

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Liver alternative TSS XM_039087447.1 0.3 0.08 0.0e+00 0.21 0.23 0.23 0.24 5.7e-23 8.7e-26 2.9e-25 6.7e-26
2 Liver alternative TSS XM_006247654.4 0.28 0.1 0.0e+00 0.18 0.2 0.2 0.21 5.4e-20 9.7e-22 1.8e-21 8.4e-23
3 Liver gene expression Abca6 0.2 0.06 0.0e+00 0.2 0.18 0.2 0.19 1.9e-21 3.0e-19 3.1e-21 3.8e-21
4 Liver mRNA stability Abca6 0.3 0.07 0.0e+00 0.3 0.31 0.3 0.31 1.7e-33 4.2e-35 1.8e-33 1.2e-34
5 Liver isoform ratio XM_039087447.1 0.22 0.08 0.0e+00 0.14 0.15 0.15 0.15 2.3e-15 2.4e-16 1.6e-16 3.4e-16
6 Liver alternative TSS XM_006247654.4 0.06 0.03 1.2e-04 0.03 0.02 0.02 0.01 1.6e-04 2.5e-03 3.7e-03 7.8e-03
7 Liver alternative TSS XM_039087445.1 0.08 0.03 6.0e-11 0.06 0.07 0.09 0.08 9.5e-07 1.2e-08 2.3e-10 5.9e-09
8 NAcc gene expression Abca6 0.08 0.04 4.4e-08 0.04 0.05 0.05 0.05 5.9e-05 1.2e-06 8.7e-07 2.7e-06
9 Liver alternative TSS XM_039087445.1 0.07 0.03 1.7e-10 0.06 0.07 0.09 0.07 1.0e-06 1.4e-08 1.8e-10 1.4e-08
10 Liver isoform ratio XM_006247654.4 0.17 0.07 7.8e-16 0.14 0.11 0.11 0.12 7.3e-15 1.5e-12 3.6e-12 1.4e-13
11 Liver isoform ratio XM_002727835.7 0.22 0.07 0.0e+00 0.28 0.24 0.29 0.05 4.2e-31 6.1e-27 9.3e-33 3.3e-06
12 Liver alternative TSS XM_006247656.4 0.22 0.07 0.0e+00 0.19 0.21 0.2 0.21 3.2e-20 7.4e-23 2.6e-22 7.8e-23
13 BLA gene expression Abca6 0.15 0.06 1.0e-08 0.13 0.12 0.1 0.12 1.3e-07 9.1e-07 7.4e-06 3.9e-07
14 Liver intron excision ratio chr10_95209800_95211153 0.08 0.04 5.4e-07 0.06 0.05 0.03 0.03 1.0e-06 2.2e-06 1.5e-04 3.0e-04
15 Liver isoform ratio XM_006247655.4 0.27 0.08 0.0e+00 0.24 0.3 0.32 0.31 2.4e-26 1.5e-33 1.0e-35 1.7e-35
16 Liver intron excision ratio chr10_95209800_95211289 0.23 0.07 0.0e+00 0.22 0.22 0.23 0.19 1.7e-24 1.8e-24 1.7e-25 3.5e-20
17 Adipose gene expression Abca6 0.24 0.07 0.0e+00 0.26 0.27 0.31 0.24 1.8e-28 4.1e-30 9.1e-35 1.6e-26
18 PL gene expression Abca6 0.1 0.04 3.1e-12 0.14 0.12 0.14 0.14 8.3e-15 2.2e-13 2.7e-15 4.9e-15
19 Liver intron excision ratio chr10_95209800_95211144 0.07 0.03 4.1e-08 0.07 0.05 0.07 0.06 5.6e-08 5.1e-06 4.3e-08 1.1e-07
20 Liver alternative TSS XM_006247656.4 0.18 0.07 0.0e+00 0.11 0.15 0.14 0.15 5.1e-12 3.6e-16 1.6e-15 2.1e-16
21 Brain gene expression Abca6 0.17 0.06 0.0e+00 0.21 0.19 0.2 0.21 5.0e-19 9.6e-18 3.4e-18 6.1e-19

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21
Bone: apparent density3.66.012.7-1.31.0-0.00.40.3-0.3-3.3-3.6-3.30.9-3.4-2.3-3.4-2.62.32.4-2.1-3.1-3.0-3.0-2.9
Area under the delay curve0.20.20.8-0.80.80.9-0.70.20.8-0.20.3-0.1-0.50.00.10.40.2-0.3-0.20.4-0.20.0-0.00.1
BMI with tail4.514.525.5-0.40.52.4-2.61.42.33.74.64.1-3.04.74.54.55.0-4.6-4.74.34.24.54.34.1
BMI without tail4.28.617.8-1.51.62.8-2.92.32.52.02.62.4-3.23.04.23.33.6-3.8-3.83.52.72.72.92.6
Body weight5.824.339.2-1.81.84.1-4.02.54.34.05.44.5-4.75.26.25.86.3-6.0-6.05.35.75.45.65.1
Weight adjusted by age2.73.08.6-0.00.21.2-1.40.71.51.32.91.4-1.52.01.72.11.6-1.8-1.81.72.22.22.22.1
Bone surface3.76.618.5-2.82.61.5-1.32.01.3-4.3-3.6-4.2-0.8-3.7-1.3-3.2-2.31.51.7-1.3-2.7-2.6-2.5-2.4
Bone volume3.55.915.9-2.92.61.6-1.41.91.4-4.0-3.5-3.8-0.7-3.5-1.2-3.1-2.01.21.4-1.1-2.6-2.4-2.3-2.2
Breakpoint value in progressive ratio session0.60.71.71.2-1.2-0.60.6-1.2-0.71.31.31.20.51.30.30.60.2-0.1-0.1-0.40.50.60.60.5
Number of licking bursts0.40.41.5-0.90.90.8-0.90.71.2-0.20.6-0.2-1.10.00.70.10.6-0.6-0.50.50.60.30.40.1
Context. condit. distance diff. score0.10.10.30.4-0.5-0.00.0-0.2-0.50.30.40.30.50.30.10.20.5-0.1-0.2-0.50.10.00.20.2
Locomotion velocity, session 10.10.10.20.10.0-0.20.2-0.10.10.40.30.4-0.30.40.1-0.2-0.0-0.2-0.20.30.30.40.20.0
Locomotion distance, session 10.50.61.60.8-0.9-1.21.3-1.3-1.11.0-0.51.01.20.6-0.5-0.1-0.2-0.0-0.1-0.30.20.60.30.3
Locomotion velocity, session 20.10.10.6-0.0-0.1-0.00.80.1-0.20.4-0.30.50.30.4-0.1-0.3-0.7-0.3-0.30.10.30.40.20.2
Locomotion distance, session 20.81.13.21.1-1.1-1.71.8-1.4-1.70.7-1.10.61.40.2-1.1-0.7-1.20.70.5-0.6-0.5-0.0-0.5-0.5
Locomotion velocity, session 31.41.63.91.8-2.0-1.91.6-1.7-1.91.70.31.71.71.40.00.90.1-0.1-0.2-0.20.51.00.60.7
Locomotion distance, session 30.40.51.20.5-0.5-1.00.5-0.6-0.9-0.3-1.0-0.31.1-0.5-0.8-0.3-0.60.80.7-0.5-0.7-0.5-0.6-0.7
Stereotopy head waving bouts, day 32.52.97.42.5-2.6-2.52.7-2.6-2.30.70.30.52.30.2-1.7-0.9-1.61.61.6-2.0-0.5-0.6-0.8-0.8
Stereotopy head waving duration, day 30.60.82.01.4-1.4-1.31.4-1.1-1.20.30.20.21.10.1-0.8-0.6-0.90.70.8-1.1-0.1-0.1-0.3-0.3
Locomotion velocity, session 70.40.51.00.1-0.2-0.70.7-0.5-0.5-0.5-0.6-0.50.8-0.6-0.8-0.8-0.80.80.8-1.0-0.9-0.8-0.8-0.7
Locomotion distance, session 70.20.31.6-0.60.50.1-0.10.10.0-0.8-1.3-0.80.0-0.8-0.4-0.4-0.20.30.3-0.5-0.7-0.5-0.6-0.7
Stereotopy head waving bouts, day 70.70.81.91.2-1.0-1.41.1-0.6-1.3-0.1-0.6-0.30.7-0.4-0.8-1.1-1.31.11.1-1.3-0.6-0.5-0.7-0.5
Stereotopy head waving duration, day 71.51.84.01.5-1.3-1.71.5-0.8-1.7-0.4-0.6-0.61.2-0.7-1.4-1.7-2.01.71.7-1.7-1.1-1.1-1.3-1.1
Locomotion velocity, session 80.30.40.8-0.60.40.9-0.20.20.70.70.60.7-0.10.70.30.90.6-0.7-0.80.90.50.80.60.8
Locomotion distance, session 80.40.62.30.9-1.0-1.01.2-1.0-1.50.7-0.80.71.40.3-0.5-0.3-0.40.20.1-0.7-0.30.0-0.2-0.1
Degree of sensitization distance0.10.10.3-0.50.40.6-0.10.20.4-0.2-0.2-0.2-0.5-0.10.2-0.20.2-0.3-0.3-0.40.10.10.10.0
Degree of sensitization stereotypy0.10.10.30.4-0.3-0.50.20.4-0.50.1-0.30.0-0.2-0.00.0-0.5-0.50.20.2-0.3-0.00.1-0.00.2
Conditioned locomotion0.10.10.5-0.40.30.2-0.20.40.1-0.4-0.7-0.3-0.3-0.20.2-0.30.0-0.1-0.1-0.0-0.2-0.3-0.3-0.4
Cocaine response after cond. corrected0.91.02.9-1.71.71.6-1.61.41.6-1.3-0.4-1.2-1.2-0.90.2-0.30.0-0.3-0.30.5-0.3-0.3-0.1-0.0
Cocaine response after cond. not corrected1.21.43.7-1.91.91.7-1.91.71.8-1.4-0.4-1.2-1.5-0.90.5-0.10.4-0.6-0.50.9-0.1-0.20.10.1
Cocaine response before conditioning0.10.10.40.3-0.2-0.5-0.10.2-0.30.1-0.10.2-0.30.30.40.50.6-0.4-0.30.50.40.30.20.1
Saline control response2.22.86.81.6-1.8-1.00.6-1.6-1.12.51.42.60.72.51.31.81.8-1.4-1.60.01.91.91.81.8
Bone: connectivity density3.45.312.8-0.40.1-0.81.5-0.4-1.1-2.7-3.6-2.81.4-2.9-2.3-2.9-2.82.42.4-2.3-2.9-2.8-2.7-2.6
Bone: cortical apparent density2.63.59.13.0-2.9-2.42.7-3.0-2.52.71.32.51.91.8-0.61.10.40.50.2-0.80.60.60.70.9
Bone: cortical area0.60.92.2-0.90.60.8-1.00.60.80.4-0.30.6-0.40.71.31.01.1-1.4-1.51.50.61.11.01.2
Bone: cortical porosity1.41.54.8-1.91.91.6-1.72.21.5-1.7-1.1-1.6-1.5-1.10.9-1.1-0.1-0.6-0.30.2-0.3-0.4-0.2-0.3
Bone: cortical porosity1.81.95.9-2.12.21.8-2.22.41.9-1.5-0.6-1.3-2.0-0.71.3-0.50.5-1.0-0.80.90.10.00.20.1
Bone: cortical thickness4.06.616.33.3-3.6-2.72.5-3.1-2.54.02.14.02.63.40.82.41.5-1.0-1.30.42.02.52.12.4
Bone: cortical thickness2.12.58.12.6-2.6-2.92.3-2.6-2.51.40.11.22.10.8-0.8-0.2-0.50.90.7-1.3-0.20.1-0.2-0.0
Bone: cortical tissue density2.53.28.62.9-2.8-2.32.6-2.9-2.42.61.32.41.71.8-0.51.10.40.50.2-0.80.60.60.60.9
Condit. Reinf. active minus inactive responses1.11.22.3-1.00.91.0-1.41.31.20.20.20.3-1.30.51.50.71.5-1.4-1.31.21.41.21.21.0
Condit. Reinf. active-inactive response ratio0.10.10.3-0.10.00.1-0.40.20.3-0.40.0-0.4-0.2-0.20.3-0.40.4-0.10.0-0.40.5-0.00.30.2
Condit. Reinf. active responses1.11.42.7-1.31.21.2-1.51.71.30.1-0.20.3-1.50.41.50.61.2-1.5-1.41.41.21.21.10.9
Condit. Reinf. inactive responses0.81.02.8-1.31.41.1-1.21.51.10.1-0.60.3-1.40.30.90.70.6-1.2-1.21.70.50.90.60.5
Incentive salience index mean0.20.20.6-0.40.30.3-0.50.60.50.1-0.10.1-0.60.20.8-0.10.3-0.6-0.50.40.80.60.60.4
Condit. Reinf. lever presses0.20.20.50.6-0.7-0.70.5-0.4-0.40.60.20.50.30.40.1-0.4-0.40.0-0.0-0.10.70.60.50.4
Condit. Reinf. active minus inactive responses2.42.910.1-2.72.52.1-2.43.22.0-1.5-2.0-1.2-2.1-0.91.60.41.1-1.3-1.21.9-0.10.0-0.1-0.5
Condit. Reinf. active-inactive response ratio2.82.99.3-2.82.72.3-2.33.02.3-1.6-1.7-1.3-2.2-1.11.20.40.7-0.9-0.81.9-0.3-0.3-0.3-0.6
Condit. Reinf. active responses1.52.16.1-2.42.11.6-1.92.41.5-1.4-2.5-1.1-1.3-1.01.30.10.8-1.2-1.11.2-0.3-0.0-0.2-0.4
Condit. Reinf. inactive responses0.20.31.30.3-0.6-0.70.3-0.4-0.80.2-1.20.20.90.20.3-0.20.0-0.5-0.5-0.50.00.40.30.3
Condit. Reinf. lever presses0.40.61.7-0.80.50.7-0.80.90.40.2-0.90.4-0.50.31.30.80.9-1.2-1.20.80.60.70.60.4
Condit. Reinf. lever reinforcers received1.21.74.8-2.21.81.5-1.82.21.4-1.2-2.2-0.9-1.3-0.81.30.31.0-1.2-1.11.2-0.20.1-0.0-0.3
Conditioned reinforcement - actives1.81.84.1-0.1-0.0-0.70.50.4-0.6-1.7-1.7-1.71.1-1.7-1.3-1.3-1.41.41.5-0.8-1.8-1.7-2.0-2.0
Conditioned reinforcement - inactives0.40.41.6-1.10.91.3-0.50.80.6-0.8-0.4-0.80.3-0.8-0.4-0.6-0.5-0.00.00.4-0.6-0.3-0.5-0.5
Conditioned locomotion0.80.92.9-1.71.51.1-1.21.51.5-0.8-1.2-0.7-0.7-0.50.80.80.8-0.8-0.70.80.20.20.1-0.0
Patch foraging indifference point 0 sec2.13.58.8-0.90.51.2-1.10.81.11.60.51.8-0.81.82.72.32.6-2.8-3.01.91.72.42.12.2
Patch foraging indifference point AUC0.20.20.5-0.00.10.1-0.2-0.30.10.70.70.7-0.50.70.60.60.5-0.4-0.40.20.20.40.40.5
Delay disc. indifference point, 0s delay0.10.20.40.3-0.2-0.60.3-0.5-0.4-0.3-0.5-0.30.1-0.4-0.50.20.10.60.6-0.5-0.3-0.4-0.3-0.3
Delay disc. indifference point, 16s delay0.50.51.8-0.70.71.3-1.30.50.90.20.90.2-0.80.60.70.50.6-0.7-0.70.50.10.30.50.8
Delay disc. indifference point, 2s delay0.10.10.3-0.60.50.3-0.1-0.30.5-0.2-0.4-0.20.2-0.4-0.30.10.10.10.20.1-0.4-0.2-0.4-0.6
Delay disc. indifference point, 24s delay1.01.03.0-1.51.71.3-1.71.41.3-1.2-0.5-1.1-1.7-0.70.5-0.4-0.4-0.3-0.10.3-0.5-0.3-0.3-0.2
Delay disc. indifference point, 4s delay0.20.20.9-0.80.70.9-0.10.00.9-0.00.6-0.0-0.3-0.0-0.00.50.5-0.10.00.8-0.4-0.2-0.4-0.6
Delay disc. indifference point, 8s delay0.40.41.31.0-0.8-0.80.7-1.2-0.70.91.00.80.40.8-0.20.90.10.20.1-0.10.10.40.30.6
Indifference point function ln k0.20.31.70.0-0.3-0.30.30.4-0.6-0.5-1.3-0.51.1-0.5-0.3-0.5-0.60.10.20.1-0.6-0.3-0.7-0.9
Indifference point function log k0.20.31.70.0-0.3-0.30.30.4-0.6-0.5-1.3-0.51.1-0.5-0.3-0.5-0.60.10.20.1-0.6-0.3-0.7-0.9
Patch foraging total patch changes 0 sec2.13.48.6-0.80.41.2-1.00.61.11.70.61.9-0.71.92.62.32.5-2.7-2.91.91.82.42.12.1
Patch foraging total patch changes 12 sec0.60.82.1-0.40.10.3-0.3-0.00.20.9-0.21.0-0.11.01.41.31.5-1.3-1.40.40.71.11.11.1
Patch foraging total patch changes 18 sec2.12.75.30.3-0.20.3-0.6-0.1-0.02.01.42.1-1.02.11.91.92.2-2.0-2.11.31.62.32.12.3
Patch foraging total patch changes 24 sec1.41.83.6-1.61.41.8-1.40.91.70.60.20.8-1.20.81.71.21.4-1.9-1.91.50.71.21.11.1
Patch foraging total patch changes 6 sec3.95.812.4-1.31.01.9-1.91.61.81.81.52.0-1.62.23.53.03.5-3.2-3.32.62.22.72.72.7
Patch foraging time to switch 0 sec0.20.30.8-0.20.40.2-0.1-0.10.5-0.80.1-0.9-0.4-0.7-0.5-0.7-0.50.80.9-0.4-0.2-0.6-0.3-0.4
Patch foraging water rate 0 sec1.72.86.4-0.30.00.7-0.70.80.71.60.71.8-0.91.92.32.22.3-2.3-2.51.61.92.01.91.9
Patch foraging water rate 12 sec1.92.86.30.8-1.10.00.2-0.70.12.41.72.50.22.41.52.42.1-1.8-1.91.02.02.22.02.0
Patch foraging water rate 18 sec0.30.41.40.8-1.0-1.11.2-0.7-1.20.3-0.60.20.8-0.1-0.50.10.00.30.3-0.8-0.2-0.4-0.5-0.8
Patch foraging water rate 24 sec0.60.83.41.3-1.4-1.51.2-0.9-1.90.3-0.80.21.3-0.0-0.8-0.3-0.30.50.4-1.0-0.3-0.1-0.6-0.8
Patch foraging water rate 6 sec0.40.62.21.2-1.5-0.91.2-1.3-1.01.00.51.00.90.80.00.50.1-0.0-0.1-0.80.50.30.30.2
Seeking ratio, delayed vs. immediate footshock3.13.56.0-0.40.61.4-1.81.41.41.32.41.4-2.22.02.42.32.2-2.1-2.12.12.12.12.11.9
Distance traveled before self-admin0.20.21.00.10.10.0-0.50.30.40.10.90.1-0.40.30.20.41.0-0.4-0.40.40.50.50.50.5
Distance traveled after self-admin0.10.10.50.4-0.5-0.1-0.20.0-0.30.10.70.10.40.3-0.10.10.7-0.2-0.2-0.30.10.10.30.5
Extensor digitorum longus weight0.51.99.20.8-0.50.2-0.7-0.10.41.53.01.5-0.61.81.21.91.8-1.0-1.01.11.71.51.61.5
Bone: elastic displacement0.60.72.61.3-1.3-1.31.1-0.6-1.60.4-0.30.41.30.3-0.5-0.6-0.60.30.3-0.8-0.3-0.0-0.3-0.4
Bone: elastic work0.10.10.50.4-0.5-0.60.3-0.4-0.70.3-0.20.40.40.40.2-0.2-0.2-0.2-0.2-0.1-0.00.30.10.0
Bone: endosteal estimation7.416.247.0-6.86.96.0-6.06.05.8-4.8-2.4-4.2-5.7-3.11.9-1.20.4-1.7-1.32.3-0.9-1.0-0.5-0.6
Bone: endosteal perimeter7.315.245.0-6.76.65.8-5.96.05.5-4.8-2.9-4.2-4.7-3.01.9-1.00.6-1.8-1.52.4-0.9-0.8-0.4-0.6
Epididymis fat weight3.37.823.30.10.11.7-1.9-0.22.12.94.83.0-2.33.33.23.53.5-2.7-2.82.33.52.93.33.0
Delta time in closed arm before/after self-admin1.71.73.9-0.70.7-0.60.10.30.1-1.7-1.5-1.80.2-2.0-1.4-1.3-1.01.41.4-0.7-1.5-1.8-1.8-2.0
Delta time in open arm before/after self-admin1.31.22.80.8-0.8-0.91.1-1.1-1.3-0.5-0.8-0.51.6-0.7-1.5-1.6-1.71.11.1-1.2-1.2-1.0-1.0-0.9
Diff in mean of infusions in LGA sessions0.60.71.70.5-0.40.1-0.1-0.10.20.71.30.7-0.51.10.81.31.0-0.7-0.80.61.11.01.11.1
Delay discount exponential model param0.30.41.41.2-1.1-1.20.9-0.5-1.10.4-0.10.30.60.2-0.2-0.3-0.10.30.2-0.50.30.10.20.1
Extinction: sum of active levers before priming0.70.74.0-0.71.11.1-1.50.81.0-0.20.4-0.2-2.0-0.00.8-0.31.0-0.6-0.50.70.10.10.30.2
Active lever presses in extinction session 60.10.11.5-0.1-0.10.10.4-1.20.10.3-0.20.20.40.0-0.4-0.30.4-0.0-0.0-0.50.00.00.1-0.1
Bone: final force0.30.51.8-1.41.21.0-1.10.71.2-1.1-0.6-0.9-0.8-0.60.3-0.2-0.1-0.3-0.30.4-0.3-0.3-0.1-0.1
Bone: final moment0.30.51.8-1.31.21.0-1.10.81.1-1.1-0.6-1.0-0.8-0.70.3-0.4-0.2-0.2-0.20.3-0.4-0.4-0.2-0.1
Food consumed during 24 hour testing period1.82.16.42.5-2.5-2.01.6-2.4-2.11.81.71.71.61.50.10.1-0.20.40.2-1.20.50.30.30.0
Glucose0.10.10.40.10.2-0.1-0.5-0.30.0-0.10.3-0.0-0.60.1-0.20.60.5-0.1-0.10.40.00.20.1-0.0
Heart weight4.25.912.1-2.72.52.8-3.13.52.9-0.1-0.10.2-2.50.82.62.12.7-3.1-2.93.12.32.32.21.9
Delay discount hyperbolic model param0.30.31.31.1-1.0-1.10.8-0.4-1.00.3-0.20.20.50.1-0.2-0.4-0.20.30.2-0.60.30.10.20.1
Intermittent access intake day 1-15 change0.20.20.50.3-0.40.10.40.1-0.30.40.00.4-0.00.30.20.50.5-0.3-0.40.20.70.70.70.7
Intermittent access intake escalation0.10.10.20.4-0.3-0.00.30.0-0.30.1-0.00.1-0.1-0.0-0.10.10.3-0.1-0.1-0.00.50.40.40.4
Intermittent access intake escalation 20.10.10.30.3-0.1-0.40.4-0.2-0.3-0.2-0.6-0.3-0.4-0.5-0.2-0.10.00.30.3-0.40.1-0.30.0-0.1
Intermitt. access day 1 inactive lever presses1.82.04.8-1.61.22.2-0.60.71.91.10.51.2-0.81.11.51.21.2-1.9-1.91.51.51.41.51.5
Intermitt. access day 15 inactive lever presses0.30.41.2-0.20.21.00.4-0.20.50.81.10.9-0.30.60.20.40.6-0.5-0.50.90.50.60.60.7
Intermitt. access escalation Index0.20.20.7-0.40.40.2-0.10.50.3-0.5-0.4-0.5-0.5-0.50.1-0.8-0.70.30.4-0.0-0.5-0.8-0.5-0.4
Intermittent access day 1 total infusions0.10.10.4-0.2-0.0-0.20.00.2-0.2-0.0-0.60.00.60.20.20.3-0.1-0.1-0.00.4-0.50.0-0.4-0.5
Intermittent access day 15 total infusions0.00.00.4-0.1-0.10.10.20.3-0.1-0.0-0.60.00.20.00.20.20.1-0.1-0.10.3-0.00.30.0-0.0
Intermittent access terminal intake (last 3 days)0.20.21.2-0.10.0-0.20.4-0.1-0.3-0.4-1.1-0.50.3-0.6-0.3-0.3-0.40.50.5-0.4-0.6-0.5-0.7-0.7
Intermittent access total infusions0.10.10.50.1-0.3-0.20.5-0.1-0.40.3-0.70.30.70.20.20.40.2-0.1-0.10.1-0.20.1-0.2-0.2
Intermittent access day 1 locomotion0.30.31.0-1.00.60.5-0.40.51.00.1-0.20.20.20.40.50.80.4-0.7-0.60.90.50.70.40.3
Intermittent access day 15 total locomotion0.40.42.0-1.01.00.3-0.40.90.8-0.3-1.4-0.3-0.6-0.40.50.60.4-0.4-0.40.70.10.20.1-0.1
Intermittent access total locomotion0.50.51.6-0.60.30.1-0.20.50.60.6-0.50.80.10.71.11.31.0-1.0-1.00.70.81.00.70.6
Intermittent access standard deviation0.10.10.6-0.10.2-0.2-0.20.50.00.1-0.30.1-0.10.10.10.40.4-0.4-0.30.80.40.80.40.3
Left kidney weight0.41.22.3-0.50.40.8-0.81.00.90.80.70.9-1.01.21.51.31.1-1.5-1.51.41.21.41.21.1
Right kidney weight0.20.71.6-0.50.30.6-0.50.60.80.40.10.4-0.80.61.21.11.3-1.1-1.10.61.10.91.00.8
Cocaine induced anxiety0.10.10.5-0.50.30.70.20.40.5-0.5-0.5-0.50.2-0.5-0.30.30.20.0-0.00.20.0-0.2-0.1-0.1
Post-drug Anxiety0.10.10.3-0.20.00.10.4-0.30.4-0.3-0.4-0.30.5-0.5-0.50.40.10.30.3-0.40.1-0.3-0.1-0.1
Baseline Anxiety0.40.52.60.8-0.6-1.00.8-1.6-0.31.00.80.90.10.6-0.3-0.4-0.30.20.2-0.80.40.10.30.3
Tail length1.75.110.5-2.42.43.2-2.62.43.20.41.10.7-3.21.03.12.22.1-2.5-2.52.41.61.21.81.8
Length with tail1.34.68.1-1.61.52.4-1.91.52.71.31.71.5-2.61.62.82.62.5-2.5-2.52.02.51.92.42.1
Length without tail0.20.51.70.6-0.6-0.30.5-1.00.20.91.20.80.00.7-0.00.90.6-0.1-0.1-0.21.30.90.90.8
Times rat made contact with spout0.60.71.3-0.20.10.6-0.0-0.00.71.00.81.0-0.31.11.00.80.9-1.1-1.10.81.21.01.11.1
Lifetime Intake0.10.11.00.1-0.3-0.30.4-0.1-0.60.1-1.00.10.80.10.00.1-0.0-0.1-0.10.0-0.40.1-0.3-0.4
Liver weight, left0.40.61.10.6-0.2-0.90.6-0.5-0.7-0.4-0.5-0.5-0.3-0.6-0.7-0.8-0.91.01.0-0.9-1.0-1.0-1.0-1.0
Liver weight, right1.11.86.52.0-1.7-2.02.1-2.5-1.51.10.80.91.00.4-1.00.1-0.61.31.2-1.4-0.3-0.9-0.8-1.2
Locomotor activity0.40.71.7-0.30.4-0.0-1.00.70.30.20.10.3-1.00.71.21.11.3-1.2-1.21.10.70.90.70.6
Locomotor testing distance1.11.84.0-0.40.30.4-1.00.90.50.80.31.0-1.11.31.81.61.9-2.0-2.01.61.61.91.51.4
Locomotor testing rearing3.96.011.9-0.2-0.10.9-0.90.61.12.21.92.4-1.22.82.93.43.4-3.2-3.22.43.23.23.13.1
Locomotion in novel chamber0.40.52.3-0.80.91.5-1.20.31.3-0.21.5-0.2-0.8-0.1-0.1-0.40.3-0.4-0.30.40.00.10.30.5
Locomotion in novel chamber post-restriction1.01.23.70.4-0.7-0.31.1-1.2-1.2-0.6-0.6-0.71.2-0.8-1.4-1.5-1.41.11.1-1.9-1.1-1.2-1.1-0.9
Fecal boli incidents, locomotor time 10.80.93.1-0.50.30.00.10.0-0.2-1.1-1.7-1.10.8-1.4-0.9-0.9-0.90.90.9-0.6-1.2-0.8-1.1-1.2
Change in fecal boli incidents, locomotor task0.30.31.11.0-0.8-0.70.4-0.9-0.90.50.70.40.10.3-0.2-0.3-0.40.30.3-0.80.10.20.20.3
Time >=10cm from walls, locomotor time 10.20.20.60.5-0.3-0.50.6-0.7-0.80.1-0.50.10.20.1-0.6-0.5-0.30.10.1-0.2-0.20.0-0.00.3
Bouts of movement, locomotor time 10.60.62.10.2-0.10.4-0.10.50.10.90.90.9-0.40.91.11.40.7-0.8-1.00.80.90.80.91.0
Total resting periods, locomotor time 10.20.20.9-0.00.10.4-0.10.50.20.50.50.5-0.40.40.61.00.4-0.4-0.50.70.50.30.50.5
Rest time, locomotor task time 10.10.10.30.10.1-0.20.2-0.20.10.40.20.2-0.30.1-0.10.30.40.10.10.60.20.30.30.3
Distance moved, locomotor task time 10.60.72.40.8-0.8-0.30.4-1.0-0.41.41.61.40.21.30.40.70.7-0.4-0.4-0.10.90.50.50.4
Vertical activity count, locomotor time 10.70.72.30.7-0.8-0.20.5-1.0-0.21.21.51.3-0.01.30.60.91.0-0.6-0.60.11.00.50.50.2
Time >=10cm from walls, locomotor time 21.01.14.11.3-1.0-0.60.7-1.1-0.61.52.01.4-0.41.40.30.50.6-0.4-0.50.41.01.11.21.6
Bouts of movement, locomotor time 21.01.13.11.2-1.1-0.30.3-1.0-0.91.61.81.60.61.70.81.20.4-0.6-0.90.10.81.11.01.2
Total resting periods, locomotor time 20.80.82.01.2-1.1-0.50.4-1.1-1.11.41.41.30.91.40.41.00.2-0.3-0.6-0.10.60.80.70.8
Rest time, locomotor task time 22.22.55.6-0.30.5-0.50.3-0.4-0.2-1.7-1.0-1.90.6-2.0-2.1-1.6-1.72.02.1-1.2-2.2-2.1-2.3-2.4
Distance moved, locomotor task time 22.73.27.22.1-2.0-1.01.2-1.6-1.02.72.52.60.12.61.31.71.7-1.1-1.20.52.11.61.92.0
Vertical activity count, locomotor time 22.32.55.71.1-1.3-0.30.7-1.0-0.22.31.82.4-0.12.31.71.82.1-1.5-1.60.92.01.61.81.7
Light reinforcement 11.22.17.42.5-2.5-2.61.8-2.2-2.71.3-0.11.22.01.0-0.30.3-0.10.50.3-1.2-0.20.4-0.10.0
Light reinforcement 20.10.10.40.2-0.0-0.3-0.30.1-0.6-0.6-0.1-0.5-0.1-0.2-0.3-0.4-0.10.10.2-0.4-0.2-0.1-0.2-0.0
Bone: marrow area7.315.745.7-6.76.85.9-5.95.95.7-4.7-2.3-4.2-5.6-3.11.9-1.10.4-1.6-1.32.3-0.9-1.0-0.5-0.7
Bone: maximum diameter2.13.910.8-3.33.22.4-2.82.72.2-3.0-2.3-2.6-1.8-2.10.2-1.3-0.4-0.3-0.10.9-1.4-1.0-0.9-0.7
Bone: maximum force0.61.13.8-1.91.71.4-1.61.21.6-1.3-1.0-1.0-1.1-0.80.6-0.20.1-0.7-0.70.8-0.10.10.20.3
Bone: maximum moment0.61.13.7-1.91.71.4-1.61.41.5-1.3-1.0-1.1-1.1-0.80.6-0.30.1-0.7-0.70.7-0.10.10.20.4
Mean time between licks in bursts0.71.02.1-0.80.91.1-1.40.91.20.11.10.1-1.40.51.21.11.1-1.0-1.01.11.41.11.10.8
Mean num. licks in bursts0.30.31.00.7-0.8-0.51.0-0.9-0.90.8-0.20.81.00.6-0.20.4-0.10.0-0.1-0.10.00.30.20.5
Cd content in liver1.92.13.90.7-0.6-1.21.0-0.6-1.3-1.4-1.3-1.61.2-1.7-2.0-1.7-1.51.91.9-1.3-1.6-1.7-1.7-1.6
Co content in liver0.50.61.9-1.11.21.4-0.91.31.4-0.60.3-0.6-1.3-0.60.2-0.10.2-0.1-0.00.5-0.2-0.5-0.2-0.1
Cu content in liver0.70.82.3-0.70.8-0.10.00.10.3-1.1-1.1-1.1-0.1-1.3-0.9-1.0-1.10.91.0-0.4-1.0-1.1-1.2-1.5
Fe content in liver0.50.61.70.8-0.8-1.00.5-0.1-1.1-0.6-0.6-0.60.9-0.5-0.7-1.3-1.10.70.7-0.8-0.6-0.5-0.5-0.4
K content in liver1.71.64.2-0.3-0.0-0.30.8-0.7-0.3-1.2-1.8-1.21.2-1.5-1.3-1.7-2.01.31.3-1.6-1.4-1.5-1.4-1.4
Mg content in liver4.24.37.50.7-1.0-1.61.9-1.4-1.6-1.5-2.3-1.62.1-2.0-2.3-2.4-2.72.42.4-2.7-2.4-2.5-2.4-2.3
Mn content in liver5.46.110.30.9-1.2-2.42.3-1.9-2.2-1.7-3.2-1.92.6-2.4-2.8-2.6-3.12.82.8-3.1-2.7-2.6-2.7-2.5
Na content in liver1.41.43.10.7-0.8-1.01.1-1.3-1.2-0.6-1.0-0.81.3-0.9-1.5-1.4-1.61.41.4-1.8-1.1-1.0-1.2-1.3
Rb content in liver0.40.41.00.9-0.8-0.91.0-0.9-0.6-0.00.5-0.20.7-0.2-1.0-0.4-0.60.90.8-0.9-0.2-0.4-0.3-0.3
Se content in liver0.40.51.00.7-0.7-0.90.8-0.9-1.00.0-0.4-0.01.0-0.2-1.0-0.6-0.90.80.8-0.7-0.5-0.6-0.6-0.7
Sr content in liver0.40.31.1-0.80.90.8-0.90.80.8-0.2-0.2-0.1-1.00.00.70.10.3-0.7-0.60.30.30.40.40.2
Zn content in liver3.13.47.8-0.30.3-0.80.50.1-0.9-2.0-2.5-2.10.7-2.1-1.7-2.6-2.41.92.0-1.7-2.4-2.2-2.5-2.8
Bone: minimum diameter5.09.327.7-5.35.14.5-4.84.44.5-3.2-2.2-2.6-3.9-1.82.0-0.11.1-2.0-1.82.5-0.3-0.00.20.0
Time in familiar zone, hab. session 10.60.62.0-0.60.40.4-0.80.5-0.1-1.4-0.7-1.40.2-1.2-0.4-1.0-0.60.60.6-0.8-0.8-0.8-0.6-0.4
Time in novel zone, hab. session 10.60.51.90.7-0.7-0.71.0-0.7-0.31.40.21.40.21.10.31.00.6-0.4-0.50.40.60.60.50.4
Total zone transitions, hab. session 10.40.61.60.6-0.5-0.40.4-0.5-0.31.20.51.2-0.11.20.60.60.5-0.7-0.90.50.91.21.01.3
Total locomotion distance, hab. session 10.91.33.61.2-1.2-1.00.9-1.1-0.61.90.91.90.41.70.71.00.6-0.7-0.90.61.31.31.21.1
Locomotion velocity, hab. session 10.81.23.00.9-0.9-0.70.6-0.8-0.31.71.11.70.01.70.81.00.7-0.8-1.00.81.31.41.31.2
Time in familiar zone, hab. session 21.31.33.4-1.41.31.7-1.71.81.5-0.40.1-0.2-1.50.11.40.61.0-1.2-1.21.40.60.80.70.8
Time in novel zone, hab. session 23.53.56.01.8-1.7-2.52.5-2.5-2.3-0.2-1.1-0.52.3-0.9-2.3-1.5-2.02.22.1-2.4-1.6-1.7-1.6-1.3
Total zone transitions, hab. session 20.30.40.90.8-0.6-0.60.3-0.2-0.80.90.50.90.30.90.2-0.2-0.1-0.4-0.50.40.50.80.60.9
Total locomotion distance, hab. session 21.21.54.32.1-1.9-1.81.2-1.3-1.81.71.11.71.21.60.10.1-0.1-0.1-0.2-0.10.91.00.80.9
Locomotion velocity, hab. session 21.11.54.32.1-1.9-1.91.3-1.4-1.81.71.11.71.11.60.00.2-0.1-0.1-0.2-0.10.81.00.70.8
Novel to familiar place preference ratio2.93.06.9-2.52.52.6-2.42.22.6-0.4-0.3-0.2-2.50.11.61.01.5-2.0-1.81.71.10.91.10.9
Novelty place preference2.32.45.6-2.32.32.4-2.22.02.3-0.4-0.3-0.2-2.30.01.30.81.2-1.7-1.51.50.90.80.90.7
Time in novel zone, NPP test2.02.04.8-2.12.12.2-2.01.92.1-0.4-0.3-0.2-2.10.11.20.81.2-1.6-1.41.30.80.70.90.8
Total zone transitions, NPP test0.71.03.21.6-1.5-1.61.5-1.3-1.81.20.11.11.40.9-0.6-0.5-0.70.20.1-0.3-0.10.60.00.3
Total locomotion distance, NPP test1.72.36.92.4-2.4-2.62.3-2.1-2.31.90.31.82.01.3-0.50.1-0.40.40.2-0.80.30.60.20.3
Locomotion velocity, NPP test1.62.25.82.3-2.3-2.42.0-2.0-2.12.20.72.11.81.6-0.20.5-0.00.0-0.2-0.30.71.00.50.4
Intraocular pressure3.24.49.4-1.61.61.8-2.22.51.80.80.71.2-2.31.52.42.02.2-2.8-2.83.12.22.52.22.1
Delta distance traveled before/after self-admin0.60.72.71.3-1.3-1.21.0-0.7-1.70.2-0.10.21.10.2-0.6-0.5-0.60.70.6-0.8-0.6-0.5-0.5-0.4
Delta ambulatory time before/after self-admin0.91.01.90.8-0.7-1.30.8-0.6-1.4-0.5-1.2-0.51.0-0.8-0.9-1.1-0.91.21.2-1.2-1.1-1.2-1.1-1.1
Parametrial fat weight0.91.84.4-0.30.6-0.50.2-0.40.1-1.4-0.9-1.5-0.2-1.7-1.4-1.6-1.51.81.8-0.8-1.8-2.0-1.9-2.1
Pavlov. Cond. lever latency1.31.73.90.4-0.4-0.80.8-0.6-1.1-1.2-1.2-1.21.2-1.4-1.7-1.2-1.11.51.5-1.4-2.0-1.8-1.7-1.4
Pavlov. Cond. magazine entry latency0.20.30.90.1-0.30.1-0.30.20.20.30.30.3-0.10.50.90.50.8-0.6-0.60.00.90.70.90.7
Pavlov. Cond. change in total contacts1.31.43.1-0.80.61.1-1.01.11.40.70.70.8-1.21.01.81.11.3-1.5-1.41.21.61.31.41.2
Pavlov. Cond. index score0.60.81.9-0.30.10.5-0.60.50.80.60.70.7-0.70.81.30.91.0-1.0-1.00.71.41.21.21.0
Pavlov. Cond. latency score0.81.02.4-0.30.10.6-0.70.50.90.80.80.8-0.81.01.41.01.0-1.1-1.20.81.51.41.41.2
Pavlov. Cond. lever contacts1.11.22.8-0.30.30.7-0.70.61.01.01.01.0-0.91.21.51.11.0-1.3-1.31.11.71.51.51.3
Pavlov. Cond. magazine entry number0.10.10.4-0.10.30.00.2-0.2-0.2-0.0-0.1-0.0-0.1-0.2-0.5-0.2-0.60.30.30.2-0.6-0.3-0.5-0.3
Pavlov. Cond. intertrial magazine entries4.55.512.5-3.23.23.3-3.43.53.1-0.4-0.20.1-3.30.42.51.21.7-2.7-2.43.21.21.61.30.9
Pavlov. Cond. lever-magazine prob. diff.0.50.61.4-0.20.10.4-0.50.40.60.60.50.6-0.60.71.20.80.9-0.9-0.90.61.21.11.10.8
Pavlov. Cond. response bias0.20.30.8-0.20.10.3-0.50.40.60.20.30.2-0.50.40.90.30.7-0.6-0.60.20.90.60.70.5
Pavlov. Cond. lever latency0.40.53.51.1-0.7-0.50.4-0.9-0.20.91.90.7-0.10.8-0.00.50.30.20.1-0.30.90.40.70.7
Pavlov. Cond. magazine entry latency0.10.10.6-0.00.20.3-0.70.7-0.1-0.30.3-0.2-0.2-0.20.0-0.1-0.2-0.0-0.10.7-0.20.2-0.00.1
Pavlov. Cond. change in total contacts0.30.41.5-0.80.70.5-1.01.20.3-0.8-1.1-0.7-0.5-0.50.4-0.4-0.1-0.3-0.30.4-0.30.1-0.2-0.3
Pavlov. Cond. index score0.50.62.4-1.11.10.8-1.31.60.5-1.0-1.1-0.9-0.7-0.80.4-0.2-0.1-0.3-0.30.9-0.6-0.1-0.4-0.5
Pavlov. Cond. latency score0.50.62.6-1.11.10.9-1.31.60.5-1.0-1.0-0.8-0.7-0.70.4-0.2-0.0-0.4-0.41.0-0.5-0.0-0.3-0.4
Pavlov. Cond. lever contacts0.20.32.2-0.40.2-0.10.10.3-0.3-0.5-1.5-0.40.4-0.6-0.1-0.5-0.50.10.1-0.1-0.8-0.5-0.7-0.7
Pavlov. Cond. magazine entry number0.20.21.10.1-0.3-0.31.0-0.90.00.2-0.30.10.5-0.1-0.3-0.3-0.20.30.4-1.00.0-0.5-0.2-0.3
Pavlov. Cond. intertrial magazine entries1.21.63.90.0-0.2-0.70.9-1.2-0.7-0.9-1.8-0.90.8-1.2-1.2-1.3-1.21.31.3-2.0-1.5-1.8-1.6-1.8
Pavlov. Cond. lever-magazine prob. diff.0.50.62.4-1.11.00.8-1.31.60.4-1.1-1.1-0.9-0.6-0.80.3-0.3-0.1-0.3-0.30.8-0.6-0.1-0.4-0.4
Pavlov. Cond. response bias0.20.31.8-0.50.40.2-0.20.5-0.1-0.7-1.3-0.50.2-0.7-0.2-0.5-0.40.20.10.1-0.9-0.6-0.7-0.7
Time in closed arm before self-admin0.70.82.00.1-0.20.4-0.40.60.30.90.90.9-0.71.21.40.90.9-1.1-1.10.80.91.11.01.1
Time in closed arm after self-admin0.30.30.9-0.50.50.5-0.50.70.80.20.70.3-1.00.30.70.50.5-0.5-0.40.90.30.20.20.1
Time in open arm before self-admin0.40.52.10.30.00.1-0.3-0.20.40.71.50.7-0.70.70.20.90.8-0.3-0.30.41.10.80.90.8
Time in open arm after self-admin0.10.10.4-0.10.20.5-0.60.20.1-0.00.30.0-0.30.20.10.10.1-0.3-0.40.30.50.60.60.6
Bone: periosteal estimation4.38.826.2-5.15.04.4-4.64.44.3-3.2-2.0-2.7-4.0-2.01.8-0.50.7-1.7-1.52.2-0.5-0.20.10.1
Bone: periosteal perimeter3.76.218.1-4.34.13.7-4.03.93.6-2.5-1.5-2.1-2.9-1.31.60.11.1-1.8-1.52.30.00.20.30.1
Bone: post-yield work0.81.14.1-2.01.91.6-1.51.11.6-1.2-1.1-1.0-1.1-1.00.1-0.4-0.1-0.4-0.30.7-0.2-0.2-0.1-0.2
Progressive ratio test 1 active lever presses1.31.34.00.9-1.3-0.50.9-1.0-0.52.01.12.00.91.91.01.51.0-0.8-0.90.40.91.10.90.9
Progressive ratio test 1 breakpoint1.41.44.20.7-1.1-0.30.7-0.8-0.32.01.12.10.62.01.31.71.1-1.1-1.20.61.01.31.01.1
Progressive ratio test 1 inactive lever presses0.30.41.50.4-0.9-0.21.0-0.8-0.80.70.00.81.20.80.0-0.2-0.6-0.2-0.2-0.50.10.40.10.2
Progressive ratio test 2 active lever presses0.40.51.2-0.40.40.6-0.30.80.70.50.30.6-0.80.70.91.00.7-0.7-0.81.10.60.70.50.5
Progressive ratio test 2 breakpoint0.60.71.6-0.40.40.7-0.20.70.80.70.50.8-0.80.91.11.30.8-0.9-0.91.20.80.80.70.7
Progressive ratio test 2 inactive lever presses0.40.51.3-1.11.10.9-0.30.90.7-0.7-1.0-0.6-0.6-0.7-0.0-0.4-0.20.0-0.01.0-0.7-0.2-0.6-0.7
Incentive Sensitization - Responses0.50.51.6-1.11.21.2-0.81.11.1-0.3-0.2-0.2-1.2-0.10.50.40.3-0.5-0.50.90.20.20.20.2
Incentive Sensitization - Breakpoint0.50.61.8-1.11.31.3-0.81.11.3-0.2-0.1-0.2-1.3-0.10.50.40.3-0.4-0.50.90.20.20.20.2
Sum of active levers in priming session hrs 5-60.40.41.1-0.10.30.9-0.70.40.50.21.00.2-0.90.50.80.30.8-0.6-0.60.70.40.60.60.7
Progressive ratio0.60.61.7-1.01.21.3-1.30.70.9-1.20.1-1.2-1.0-0.9-0.5-0.8-0.20.20.30.1-0.5-0.5-0.4-0.2
Food seeking constrained by brief footshock0.60.71.8-1.31.31.2-0.91.21.3-0.9-0.2-0.8-1.2-0.80.1-1.0-0.30.00.20.6-0.1-0.5-0.2-0.4
Seeking ratio, punishment vs. effort0.10.10.50.0-0.2-0.40.50.10.00.7-0.20.70.10.50.60.40.2-0.3-0.30.40.40.20.30.0
Retroperitoneal fat weight2.27.213.0-0.10.21.7-1.60.52.02.73.62.8-2.33.23.53.13.2-3.0-3.02.33.52.93.43.2
Reaction time number correct0.81.22.80.1-0.2-0.70.2-0.3-0.9-1.3-1.3-1.30.7-1.3-1.3-1.0-1.11.11.2-1.3-1.3-1.1-1.5-1.7
Reaction time mean minus median0.50.61.60.4-0.1-0.80.3-0.9-0.2-0.40.3-0.50.2-0.7-0.9-1.0-0.91.21.3-0.9-0.7-1.2-0.8-0.7
Reaction time mean minus median AUC1.92.54.30.4-0.4-1.40.7-1.3-0.8-1.2-1.3-1.31.2-1.7-1.7-2.1-2.02.02.1-2.0-1.9-2.0-1.8-1.7
Reaction time num false alarms0.81.14.3-1.61.51.3-2.11.81.0-1.1-1.1-0.9-0.8-0.50.90.10.7-1.0-0.90.8-0.40.3-0.1-0.1
Reaction time num false alarms AUC0.91.23.2-1.51.30.9-1.71.40.6-1.7-1.8-1.5-0.3-1.30.1-0.8-0.2-0.1-0.1-0.1-1.2-0.6-0.9-0.9
Reaction time trials correct on left0.81.22.80.1-0.2-0.70.2-0.3-0.9-1.3-1.3-1.30.7-1.3-1.3-1.0-1.11.11.2-1.3-1.3-1.1-1.5-1.7
Reaction time trials on left0.91.33.00.1-0.2-0.70.3-0.3-0.9-1.4-1.4-1.40.7-1.4-1.4-1.1-1.21.21.3-1.4-1.4-1.2-1.6-1.7
Reaction time mean0.30.41.20.8-0.5-0.80.8-0.8-0.5-0.1-0.0-0.30.1-0.5-0.7-0.7-0.71.11.0-0.8-0.4-0.8-0.4-0.2
Reaction time mean AUC0.30.41.00.9-0.7-0.81.0-0.9-0.60.10.1-0.10.3-0.3-0.6-0.6-0.71.00.9-0.7-0.3-0.7-0.2-0.1
Median of all reaction times0.30.40.90.9-0.7-0.81.0-0.7-0.70.0-0.2-0.20.1-0.4-0.6-0.6-0.50.90.9-0.8-0.3-0.6-0.20.0
Reaction time omissions2.83.88.61.3-1.2-2.01.7-1.9-1.9-1.2-1.6-1.41.7-1.7-2.3-2.2-2.32.52.4-2.9-2.0-2.2-1.9-1.6
Reaction time false alarm rate0.50.82.8-1.31.21.2-1.71.41.0-0.7-0.6-0.5-0.7-0.30.90.10.7-0.9-0.80.8-0.10.30.20.3
Reaction time premature initiation rate1.11.53.5-0.70.41.0-0.70.51.31.11.21.2-0.31.31.41.91.6-1.6-1.71.01.41.51.41.3
Reaction time premature initiations0.10.10.6-0.50.10.3-0.30.10.50.1-0.00.20.40.20.30.80.5-0.6-0.6-0.10.20.40.2-0.0
Std. dev. reaction times1.21.63.60.7-0.5-1.31.0-1.4-0.8-0.6-0.5-0.91.0-1.3-1.6-1.5-1.61.91.9-1.6-1.3-1.7-1.3-1.1
Reaction time trials completed0.91.33.00.1-0.2-0.70.3-0.3-0.9-1.4-1.4-1.40.7-1.4-1.4-1.1-1.21.21.3-1.4-1.4-1.2-1.6-1.7
Reaction time trials AUC0.81.22.70.2-0.3-0.70.3-0.4-0.8-1.2-1.2-1.30.7-1.3-1.3-1.0-1.11.21.2-1.3-1.3-1.2-1.5-1.6
Run reversals in cocaine runway, females3.13.013.40.5-0.20.7-0.5-0.21.12.13.72.1-1.42.11.51.81.7-1.3-1.41.32.41.82.32.2
Run reversals in cocaine runway, males1.01.03.1-1.41.61.6-1.31.61.3-0.40.2-0.3-1.8-0.10.70.80.7-0.7-0.70.90.30.00.30.5
Latency to leave start box in cocaine runway2.72.97.01.9-1.8-1.01.1-1.7-0.82.62.62.50.12.61.22.11.8-1.0-1.10.41.71.61.51.4
Latency to leave start box in cocaine runway, F5.96.513.11.1-1.1-0.00.3-1.00.23.53.33.5-0.73.62.33.53.3-2.6-2.71.73.33.13.02.8
Latency to leave start box in cocaine runway, M1.51.44.02.0-1.8-2.01.5-1.6-1.60.30.80.11.00.2-0.5-0.8-1.01.31.3-1.1-0.7-0.8-0.8-0.7
Std. dev. time between licks in bursts0.40.41.41.0-1.1-0.71.0-1.2-0.40.81.20.60.70.6-0.30.1-0.40.30.3-0.20.50.40.30.1
Total sessions with >9 infusions0.40.41.90.5-0.8-1.00.6-0.5-0.80.7-0.70.71.40.70.20.70.3-0.3-0.30.30.10.80.10.1
Short access day 1 total inactive lever presses0.10.10.3-0.1-0.00.10.2-0.30.00.5-0.20.50.30.40.00.40.1-0.3-0.30.20.30.60.30.3
Short access day 10 total inactive lever presses0.30.32.0-0.90.91.4-0.50.40.7-0.3-0.2-0.2-0.9-0.20.1-0.10.2-0.5-0.50.20.30.20.30.4
Short access day 1 total infusions0.40.41.00.9-1.0-1.00.6-0.8-1.00.8-0.20.90.80.90.10.20.4-0.5-0.5-0.00.30.80.40.4
Short access day 10 total infusions0.30.32.30.3-0.7-0.30.6-0.8-0.70.7-0.30.71.50.70.10.1-0.3-0.2-0.3-0.1-0.20.4-0.1-0.1
Short access total infusions0.20.21.20.4-0.6-0.60.5-0.2-1.00.1-1.10.21.10.30.1-0.1-0.3-0.1-0.1-0.2-0.30.2-0.3-0.2
Short access day 1 locomotion0.50.51.30.4-0.8-0.40.7-0.7-0.21.00.31.00.91.20.70.80.3-0.7-0.8-0.10.70.90.80.8
Short access day 10 total locomotion0.40.51.3-0.90.80.4-1.11.00.6-0.3-0.3-0.2-0.50.20.91.00.6-0.9-0.80.50.60.70.50.4
Short access total locomotion0.40.51.10.4-0.7-0.60.5-0.6-0.30.80.20.80.81.10.71.00.4-0.7-0.60.00.81.00.70.6
One hour access (0.3 mA shock)0.40.43.4-0.50.40.10.20.6-0.4-0.7-1.8-0.60.3-0.8-0.0-0.3-0.30.30.20.0-1.0-0.6-0.9-0.9
Compulsive drug intake0.60.62.0-1.41.40.9-0.70.81.0-0.9-1.2-0.8-1.1-1.10.0-0.7-0.40.00.00.1-0.3-0.5-0.3-0.4
One hour access (shock baseline)0.30.40.80.4-0.3-0.50.6-0.2-0.8-0.4-0.8-0.50.8-0.4-0.6-0.4-0.40.70.7-0.3-0.9-0.7-0.9-0.9
Social response proportion0.80.82.5-0.80.80.3-0.3-0.00.7-1.4-1.0-1.4-0.3-1.6-0.9-0.9-1.00.80.8-0.8-0.9-1.1-0.9-0.8
Social responses0.50.71.90.7-1.0-1.00.8-1.1-1.0-0.2-0.8-0.21.4-0.5-0.7-0.6-1.10.70.6-1.4-0.6-0.4-0.6-0.7
Social time1.21.54.2-1.11.10.5-0.90.90.6-2.0-1.4-2.0-0.3-2.0-0.9-1.3-1.00.91.1-0.5-1.2-1.4-1.3-1.6
Soleus weight0.41.24.2-1.71.91.0-2.11.71.4-1.3-0.3-1.1-1.9-0.80.5-0.30.6-0.4-0.30.7-0.4-0.2-0.2-0.2
Bone: stiffness0.30.51.7-1.31.21.0-1.00.41.3-0.9-0.4-0.8-0.8-0.80.1-0.1-0.0-0.1-0.20.5-0.3-0.2-0.00.2
Tibialis anterior weight0.41.32.9-0.20.41.0-1.30.90.90.61.60.7-1.41.11.71.21.5-1.2-1.20.91.11.11.31.5
Time to tail flick, vehicle, before self-admin0.40.42.0-0.90.81.4-0.20.61.2-0.10.6-0.1-0.4-0.10.10.70.4-0.4-0.50.80.50.20.40.4
Time to tail flick, vehicle, after self-admin1.01.03.1-1.71.71.6-1.51.21.8-1.3-0.4-1.2-1.0-1.2-0.1-0.50.3-0.3-0.00.3-0.1-0.3-0.1-0.3
Time to tail flick, test, before self-admin2.82.78.2-2.62.72.7-2.32.52.9-1.4-0.1-1.3-2.6-1.11.10.40.9-0.7-0.61.10.0-0.4-0.0-0.1
Time to tail flick, test, after self-admin0.70.72.5-1.61.61.4-0.70.41.3-0.9-1.1-0.8-1.0-1.0-0.3-0.50.2-0.3-0.10.1-0.4-0.5-0.5-0.4
Delta time to tail flick, vehicle, before/after SA1.41.43.0-0.40.1-0.30.2-0.6-0.1-1.2-1.7-1.31.2-1.6-1.3-1.6-1.51.21.3-1.6-1.3-1.3-1.3-1.4
Delta time to tail flick, test, before/after SA0.50.42.3-0.40.3-0.20.2-0.4-0.1-0.6-1.5-0.60.3-0.8-1.1-1.0-0.70.30.4-0.5-0.6-0.5-0.6-0.5
Tibia length1.74.98.1-1.21.22.3-2.02.02.31.22.41.3-2.11.92.82.42.3-2.6-2.52.82.62.42.52.3
Ambulatory time before self-admin0.40.42.50.3-0.0-0.1-0.4-0.10.50.71.60.6-0.50.80.30.50.8-0.4-0.50.70.60.70.60.6
Ambulatory time after self-admin0.10.10.50.7-0.7-0.70.1-0.3-0.50.10.60.00.50.1-0.2-0.30.50.20.2-0.5-0.1-0.2-0.10.0
Bone: tissue strength1.71.76.11.7-2.0-1.92.0-1.8-2.00.7-0.40.62.50.2-1.4-0.5-1.00.90.7-1.4-0.3-0.0-0.30.0
Total heroin consumption0.40.51.1-0.40.30.10.4-0.70.3-0.5-0.2-0.60.6-0.7-0.8-0.9-0.70.90.8-0.6-1.1-0.9-0.9-0.8
Bone: trabecular number4.06.314.0-0.50.2-0.91.3-0.5-1.1-3.0-3.7-3.11.6-3.2-2.6-3.3-2.92.62.6-2.7-3.1-3.0-3.0-2.8
Bone: trabecular spacing3.14.09.40.7-0.40.5-0.6-0.10.92.83.12.8-1.02.71.82.62.3-2.0-1.91.92.62.32.32.1
Bone: trabecular thickness1.51.84.9-1.91.60.8-1.01.20.9-2.2-2.2-2.1-0.4-1.9-0.4-1.4-0.60.50.5-0.2-1.5-1.2-1.3-1.3
Bone: trabecular tissue density0.91.33.61.2-1.1-0.90.5-1.1-0.31.91.71.80.41.60.61.61.1-0.4-0.50.71.31.21.11.0
Water consumed over 24 hours2.32.87.62.7-2.7-2.62.3-2.8-2.61.30.71.02.40.8-0.9-0.6-0.91.10.9-1.9-0.2-0.1-0.3-0.3
Number of responses in last shaping day0.90.92.20.8-0.9-0.50.6-0.2-0.31.41.51.40.51.40.61.10.5-0.7-0.71.01.01.31.01.0