Hub : Genes

Abca6

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Liver alternative TSS XM_006247654.5 0.29 0.08 0.0e+00 0.19 0.19 0.2 0.2 1.5e-20 1.6e-20 2.2e-21 2.8e-22
2 Liver alternative TSS XM_039087447.2 0.26 0.07 0.0e+00 0.13 0.22 0.21 0.22 5.6e-14 6.5e-24 5.1e-23 1.0e-23
3 Liver mRNA stability Abca6 0.31 0.08 0.0e+00 0.31 0.32 0.31 0.31 5.9e-35 4.9e-36 4.0e-35 3.9e-35
4 Liver isoform ratio XM_002727835.8 0.11 0.04 6.7e-16 0.12 0.12 0.14 0.12 1.6e-13 5.1e-13 2.7e-15 4.1e-13
5 Liver isoform ratio XM_039087447.2 0.22 0.08 0.0e+00 0.14 0.14 0.12 0.12 7.1e-15 1.0e-15 1.2e-13 1.2e-13
6 Liver isoform ratio XM_063270045.1 0.03 0.02 1.1e-03 0.03 0.01 0.02 0.02 5.2e-04 9.1e-03 1.9e-03 8.7e-04
7 Liver alternative TSS XM_006247655.5 0.04 0.02 6.8e-04 0.01 0.03 0.02 0.01 1.1e-02 2.7e-04 4.4e-03 1.0e-02
8 IL gene expression Abca6 0.21 0.11 6.9e-03 0.02 0.1 0.03 0.04 1.2e-01 2.8e-03 8.5e-02 4.9e-02
9 pVTA gene expression Abca6 0.04 0.02 3.7e-03 0.04 0.03 0.02 0.03 5.0e-04 2.6e-03 1.5e-02 2.1e-03
10 NAcc gene expression Abca6 0.07 0.03 4.2e-15 0.07 0.1 0.09 0.09 2.6e-11 9.5e-15 1.3e-13 6.5e-14
11 Liver alternative TSS XM_006247654.5 0.06 0.03 3.8e-06 0.03 0.05 0.04 0.03 2.1e-04 1.3e-06 2.6e-05 2.8e-04
12 Liver gene expression Abca6 0.21 0.07 0.0e+00 0.2 0.17 0.19 0.19 1.3e-21 5.7e-19 3.4e-20 5.3e-21
13 Liver intron excision ratio chr10_95709256_95710607 0.08 0.04 4.7e-07 0.05 0.06 0.04 0.04 1.7e-06 8.3e-07 1.9e-05 7.6e-05
14 Brain gene expression Abca6 0.17 0.06 0.0e+00 0.21 0.21 0.18 0.23 2.2e-19 3.6e-19 8.8e-17 2.2e-21
15 Liver isoform ratio XM_006247654.5 0.14 0.06 2.0e-11 0.1 0.08 0.08 0.08 4.8e-11 3.7e-09 6.8e-09 2.9e-09
16 Liver intron excision ratio chr10_95709256_95710743 0.22 0.07 0.0e+00 0.23 0.21 0.23 0.16 1.1e-24 9.8e-23 8.8e-26 1.7e-17
17 PL gene expression Abca6 0.11 0.04 7.6e-14 0.16 0.14 0.15 0.15 9.4e-17 7.9e-15 1.2e-15 2.1e-16
18 Liver isoform ratio XM_006247655.5 0.3 0.09 0.0e+00 0.29 0.31 0.33 0.23 7.7e-33 8.2e-35 8.3e-38 3.4e-25
19 Liver intron excision ratio chr10_95709256_95710598 0.07 0.03 1.2e-07 0.08 0.04 0.07 0.04 2.6e-09 2.4e-05 4.8e-08 6.3e-05
20 BLA gene expression Abca6 0.15 0.06 2.8e-08 0.13 0.12 0.13 0.12 2.7e-07 9.9e-07 2.8e-07 3.8e-07
21 Adipose gene expression Abca6 0.28 0.08 0.0e+00 0.26 0.28 0.31 0.32 7.3e-29 4.4e-31 2.2e-35 9.4e-36
22 IC gene expression Abca6 0.12 0.06 2.3e-04 0.11 0.11 0.08 0.12 2.4e-05 2.0e-05 4.3e-04 1.3e-05

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22
Bone: apparent density2.85.113.22.2-1.50.4-3.3-1.2-2.10.53.1-0.43.61.5-0.32.13.20.32.1-2.92.1-3.0-3.02.32.7
Area under the delay curve0.10.10.70.4-0.1-0.50.3-0.00.6-0.0-0.10.2-0.2-0.00.20.2-0.0-0.60.0-0.1-0.1-0.00.5-0.3-0.9
BMI with tail4.013.826.3-0.9-0.2-2.94.3-0.72.01.9-5.12.6-4.5-4.22.6-4.4-4.7-2.5-4.64.6-4.64.74.5-4.5-4.1
BMI without tail4.825.555.2-0.8-0.8-3.95.6-1.72.23.1-7.43.9-5.4-6.04.0-6.8-6.0-3.9-6.35.9-6.25.96.0-5.9-5.2
Body weight7.231.350.30.9-2.5-5.75.0-3.11.44.1-6.65.5-5.2-6.65.5-6.6-6.3-5.3-7.16.5-7.06.46.1-7.0-6.4
Weight adjusted by age1.23.68.0-0.6-0.1-1.52.2-0.20.90.5-1.81.4-2.5-1.71.5-1.5-2.5-1.4-2.32.7-2.22.62.3-2.5-2.8
Bone surface3.16.115.23.8-3.1-1.4-3.7-2.6-3.12.02.91.23.90.51.31.43.2-1.21.3-2.81.1-2.9-2.91.51.9
Bone volume2.85.614.33.8-3.0-1.4-3.5-2.6-2.81.92.91.23.70.41.31.43.0-1.31.1-2.60.9-2.7-2.81.31.9
Breakpoint value in progressive ratio session0.71.33.0-1.71.70.81.51.61.3-1.4-1.7-0.9-1.40.4-1.0-0.1-1.10.9-0.20.90.00.91.0-0.2-1.1
Number of licking bursts0.10.30.90.5-0.7-0.8-0.0-0.6-0.70.6-0.51.0-0.1-0.60.6-0.4-0.2-0.6-0.30.2-0.40.50.2-0.6-0.8
Context. condit. distance diff. score0.10.10.6-0.40.30.10.30.40.6-0.4-0.20.0-0.50.1-0.10.0-0.4-0.1-0.10.2-0.00.10.2-0.1-0.8
Locomotion velocity, session 10.00.00.2-0.10.1-0.00.3-0.00.30.1-0.20.0-0.1-0.2-0.0-0.2-0.2-0.1-0.20.1-0.20.2-0.0-0.30.4
Locomotion distance, session 10.50.73.4-1.00.91.20.70.91.8-0.70.7-1.0-0.20.3-1.00.4-0.30.80.10.00.10.1-0.10.31.6
Locomotion velocity, session 20.20.34.0-0.20.00.50.2-0.30.60.30.50.10.3-0.30.1-0.40.1-0.0-0.40.1-0.3-0.0-0.2-0.12.0
Locomotion distance, session 20.91.36.7-1.11.11.70.21.01.6-0.81.3-1.40.40.8-1.40.90.31.40.5-0.60.6-0.6-0.71.02.6
Locomotion velocity, session 31.31.54.1-2.01.71.51.41.61.9-0.9-0.2-1.8-1.10.0-1.8-0.0-0.91.8-0.00.50.10.50.60.21.1
Locomotion distance, session 30.50.61.8-0.20.30.6-0.20.60.7-0.61.4-1.20.40.7-1.21.10.31.20.8-0.70.9-0.5-0.70.80.7
Stereotopy head waving bouts, day 32.73.27.6-2.12.72.80.32.61.3-2.40.2-2.6-0.12.0-2.61.60.42.41.6-0.71.8-0.6-0.71.61.4
Stereotopy head waving duration, day 30.81.02.3-1.31.51.50.21.40.4-1.20.1-1.5-0.20.9-1.50.70.31.40.9-0.41.0-0.4-0.30.81.0
Locomotion velocity, session 70.40.41.0-0.00.20.7-0.40.40.5-0.50.9-0.70.60.6-0.70.80.60.80.7-0.70.7-0.6-0.90.81.0
Locomotion distance, session 70.20.21.10.4-0.50.2-0.4-0.20.80.31.1-0.20.80.2-0.20.60.40.30.2-0.40.3-0.4-0.50.40.6
Stereotopy head waving bouts, day 70.91.01.6-0.60.60.9-0.90.5-1.1-0.70.7-1.20.81.0-1.20.70.91.31.2-1.01.2-1.0-1.21.21.3
Stereotopy head waving duration, day 71.41.72.7-0.81.01.4-1.10.9-1.2-1.10.9-1.50.91.4-1.51.11.31.61.6-1.41.7-1.4-1.51.61.6
Locomotion velocity, session 80.30.40.90.2-0.1-0.30.6-0.20.90.1-0.00.9-0.6-0.40.9-0.3-0.5-0.9-0.80.7-0.70.60.8-0.90.1
Locomotion distance, session 80.40.62.9-0.80.71.10.40.71.7-0.60.9-0.80.00.4-0.90.5-0.10.70.2-0.20.3-0.4-0.40.61.4
Degree of sensitization distance0.10.10.30.1-0.2-0.00.1-0.30.20.4-0.40.50.1-0.40.5-0.4-0.1-0.5-0.50.3-0.50.30.3-0.30.2
Degree of sensitization stereotypy0.10.11.0-0.30.00.1-0.4-0.2-1.00.1-0.0-0.40.3-0.0-0.4-0.40.20.50.2-0.20.2-0.3-0.50.30.7
Conditioned locomotion0.10.20.60.3-0.6-0.2-0.4-0.7-0.40.7-0.20.30.8-0.40.3-0.40.3-0.4-0.1-0.3-0.0-0.3-0.20.10.4
Cocaine response after cond. corrected0.91.33.41.8-1.6-1.7-0.7-1.5-1.31.40.11.90.6-0.71.8-0.30.3-1.8-0.70.1-0.8-0.00.0-0.7-0.9
Cocaine response after cond. not corrected1.11.64.01.8-1.8-1.9-0.7-1.8-1.41.7-0.22.00.5-1.02.0-0.70.2-1.9-0.80.2-1.00.10.3-0.9-1.0
Cocaine response before conditioning0.10.10.3-0.50.30.10.30.10.10.3-0.6-0.4-0.3-0.5-0.3-0.5-0.20.4-0.20.2-0.30.30.4-0.20.3
Saline control response2.43.39.1-2.11.60.62.91.43.0-0.6-2.5-0.4-2.5-1.2-0.4-1.7-2.60.3-1.72.1-1.62.12.1-1.3-1.2
Bone: connectivity density2.74.311.21.0-0.51.5-2.7-0.4-0.90.12.5-1.23.31.6-1.11.92.91.22.1-2.52.1-2.7-2.62.53.3
Bone: cortical apparent density2.84.412.7-3.63.43.11.83.22.7-2.6-0.9-2.9-1.71.3-2.80.5-1.12.80.70.90.80.71.10.90.5
Bone: cortical area0.30.41.30.4-0.4-0.70.5-0.50.51.1-0.70.5-0.1-1.10.4-0.9-0.4-0.4-1.00.5-1.00.50.4-0.50.5
Bone: cortical porosity1.71.95.32.1-2.3-1.7-1.5-2.3-1.92.00.31.41.6-1.11.4-0.81.1-1.4-0.2-0.9-0.2-0.8-0.8-0.10.2
Bone: cortical porosity1.82.05.02.0-2.2-2.2-0.9-2.2-1.72.1-0.41.70.8-1.51.7-1.20.3-1.7-0.8-0.2-0.8-0.1-0.2-0.8-0.8
Bone: cortical thickness3.96.619.0-4.43.82.83.53.34.2-2.0-2.2-2.6-3.1-0.1-2.7-0.9-2.62.6-0.92.2-0.62.22.2-0.40.4
Bone: cortical thickness2.53.08.2-2.82.82.60.92.61.7-2.0-0.6-2.7-0.61.2-2.80.6-0.32.90.80.10.90.0-0.21.31.0
Bone: cortical tissue density2.74.212.2-3.53.33.11.83.12.6-2.6-0.9-2.8-1.71.3-2.80.5-1.02.70.70.80.80.61.10.90.4
Condit. Reinf. active minus inactive responses0.91.02.20.3-1.0-1.20.3-1.0-0.31.3-1.00.6-0.5-1.50.6-1.4-0.9-0.6-1.21.2-1.21.30.8-1.2-0.9
Condit. Reinf. active-inactive response ratio0.10.10.9-0.1-0.1-0.3-0.4-0.0-1.0-0.0-0.5-0.30.00.0-0.3-0.2-0.00.30.10.30.00.3-0.2-0.0-0.8
Condit. Reinf. active responses1.01.33.60.6-1.3-1.40.1-1.5-0.51.9-0.71.0-0.2-1.81.0-1.6-0.8-0.9-1.41.1-1.31.20.6-1.3-0.2
Condit. Reinf. inactive responses0.81.14.10.9-1.4-1.3-0.0-1.6-0.22.00.11.30.2-1.51.2-1.1-0.2-1.2-1.10.4-1.10.40.3-1.00.8
Incentive salience index mean0.20.20.6-0.0-0.4-0.4-0.1-0.5-0.50.6-0.50.0-0.1-0.70.0-0.8-0.40.1-0.50.6-0.50.70.0-0.4-0.2
Condit. Reinf. lever presses0.20.31.1-1.00.70.80.10.70.2-0.5-0.1-0.8-0.20.2-0.8-0.0-0.41.00.10.40.10.5-0.30.10.4
Condit. Reinf. active minus inactive responses2.03.211.22.1-3.0-2.3-1.1-3.2-1.83.30.11.81.4-2.31.8-1.90.5-1.9-1.1-0.1-1.20.00.3-1.00.5
Condit. Reinf. active-inactive response ratio1.82.99.72.3-3.0-2.3-1.2-3.1-1.93.00.41.91.3-1.91.9-1.60.7-1.9-0.8-0.2-1.0-0.10.3-0.90.0
Condit. Reinf. active responses1.72.59.12.0-2.7-1.8-1.1-2.8-1.23.00.51.61.6-2.01.5-1.40.5-1.6-0.8-0.5-1.0-0.2-0.1-0.61.1
Condit. Reinf. inactive responses0.10.22.5-0.3-0.00.40.1-0.10.70.50.1-0.20.5-0.5-0.2-0.3-0.20.3-0.3-0.3-0.3-0.2-0.30.21.6
Condit. Reinf. lever presses0.50.72.60.7-1.1-0.8-0.2-1.3-0.31.6-0.50.80.5-1.40.8-1.3-0.2-0.8-0.80.2-0.90.30.3-0.60.5
Condit. Reinf. lever reinforcers received1.52.17.71.8-2.5-1.7-0.9-2.5-0.92.80.11.51.3-1.91.5-1.50.3-1.5-0.9-0.3-1.0-0.10.1-0.70.8
Conditioned reinforcement - actives0.10.41.40.7-1.0-0.5-0.5-1.1-0.31.20.80.60.8-0.50.6-0.20.5-0.4-0.2-0.2-0.2-0.2-0.2-0.11.0
Conditioned reinforcement - inactives0.41.03.11.4-1.3-1.10.0-1.30.20.91.01.70.2-0.61.70.0-0.1-1.8-1.00.5-1.00.3-0.2-1.1-0.4
Conditioned locomotion1.21.83.50.9-1.5-1.50.7-1.70.71.8-0.41.4-0.5-1.91.4-1.4-1.1-1.4-1.71.4-1.71.61.3-1.7-0.6
Patch foraging indifference point 0 sec1.44.09.1-0.1-1.0-1.22.0-1.41.92.2-2.01.5-1.4-3.01.5-3.0-2.4-1.7-2.92.1-2.72.02.4-2.3-0.3
Patch foraging indifference point AUC0.20.41.2-0.60.4-0.01.00.51.0-0.3-0.7-0.1-1.1-0.4-0.2-0.6-0.90.4-0.50.7-0.50.70.7-0.3-0.6
Delay disc. indifference point, 0s delay0.40.41.2-0.40.50.6-0.10.80.7-0.70.4-1.1-0.00.7-1.00.80.21.01.0-0.41.0-0.30.10.6-0.4
Delay disc. indifference point, 16s delay0.40.52.00.6-0.5-1.40.2-0.4-0.70.4-1.01.0-0.4-0.51.0-0.4-0.4-1.4-0.50.3-0.60.30.3-0.8-1.2
Delay disc. indifference point, 2s delay0.10.10.60.6-0.20.10.10.10.8-0.20.6-0.30.20.4-0.40.60.20.20.3-0.20.3-0.30.10.3-0.2
Delay disc. indifference point, 24s delay0.50.85.01.2-1.3-1.6-1.0-1.2-2.21.2-0.10.50.7-0.60.6-0.40.5-0.9-0.0-0.4-0.1-0.3-0.3-0.2-0.4
Delay disc. indifference point, 4s delay0.20.21.30.50.10.00.50.11.1-0.3-0.20.2-0.40.10.20.10.2-0.50.1-0.20.1-0.10.7-0.2-0.7
Delay disc. indifference point, 8s delay0.40.72.4-0.91.20.71.01.31.6-1.1-0.5-1.1-0.90.5-1.10.5-0.40.70.50.20.40.21.00.1-1.0
Indifference point function ln k0.20.63.60.1-0.40.2-0.8-0.6-0.70.80.7-0.81.1-0.2-0.7-0.10.80.50.3-0.80.5-1.0-0.70.71.9
Indifference point function log k0.20.63.60.1-0.40.2-0.8-0.6-0.70.80.7-0.81.1-0.2-0.7-0.10.80.50.3-0.80.5-1.0-0.70.71.9
Patch foraging total patch changes 0 sec1.44.19.0-0.2-0.8-1.12.1-1.31.92.0-2.11.5-1.5-2.91.4-3.0-2.5-1.6-2.92.2-2.72.12.5-2.3-0.3
Patch foraging total patch changes 12 sec0.81.03.2-0.2-0.3-0.21.2-0.41.80.9-1.00.4-0.8-1.50.3-1.6-1.3-0.3-1.31.1-1.31.21.3-0.9-0.3
Patch foraging total patch changes 18 sec1.22.86.6-1.20.2-0.62.3-0.01.90.7-1.90.5-2.2-2.00.4-2.1-2.6-0.4-2.22.2-2.02.32.0-1.9-0.7
Patch foraging total patch changes 24 sec0.62.04.30.8-1.3-1.60.9-1.50.31.8-1.01.6-0.6-2.11.6-1.9-1.1-1.5-2.11.2-2.01.21.1-1.5-0.0
Patch foraging total patch changes 6 sec4.17.015.1-0.0-1.3-2.02.7-1.72.02.4-2.82.1-2.5-3.72.0-3.9-3.2-2.1-3.42.9-3.32.83.4-3.0-2.1
Patch foraging time to switch 0 sec0.10.52.00.9-0.3-0.1-0.60.1-0.7-0.70.60.20.61.00.31.10.6-0.30.8-0.60.7-0.5-0.70.3-1.4
Patch foraging water rate 0 sec0.83.19.0-1.1-0.2-0.61.7-0.81.41.8-2.50.8-1.5-2.60.7-3.0-2.0-0.8-2.32.1-2.22.12.3-1.80.3
Patch foraging water rate 12 sec0.62.45.0-1.91.10.32.20.72.1-0.0-2.1-0.1-2.1-1.2-0.1-1.5-2.10.0-1.82.2-1.62.02.2-1.4-0.4
Patch foraging water rate 18 sec0.30.72.4-1.20.81.3-0.10.60.2-0.20.0-1.40.30.4-1.50.00.41.40.5-0.30.7-0.3-0.00.91.5
Patch foraging water rate 24 sec0.50.73.4-1.20.91.0-0.20.70.2-0.30.3-1.30.20.5-1.40.40.31.30.4-0.20.5-0.3-0.30.71.8
Patch foraging water rate 6 sec0.50.72.7-1.61.41.10.71.11.0-0.8-1.3-1.1-0.60.2-1.0-0.4-0.51.1-0.10.5-0.00.50.50.20.5
Seeking ratio, delayed vs. immediate footshock2.43.46.6-0.6-0.3-1.71.7-0.60.11.3-2.51.4-2.4-2.31.4-2.4-2.0-1.3-1.92.1-1.92.12.6-2.2-2.2
Distance traveled before self-admin0.10.30.9-0.80.5-0.20.80.40.1-0.4-0.60.2-0.90.00.1-0.0-0.7-0.2-0.40.7-0.30.80.8-0.6-1.0
Distance traveled after self-admin0.10.20.7-0.70.5-0.10.60.40.1-0.4-0.6-0.0-0.7-0.00.0-0.1-0.60.1-0.40.6-0.20.50.4-0.3-0.8
Extensor digitorum longus weight0.62.312.9-0.90.7-0.92.10.91.1-0.7-1.50.4-2.6-0.60.4-0.4-2.0-0.2-1.01.8-0.91.82.0-1.5-3.6
Bone: elastic displacement0.50.62.3-1.51.11.20.40.80.6-0.60.2-1.3-0.20.3-1.4-0.0-0.21.20.20.20.3-0.1-0.20.51.5
Bone: elastic work0.20.20.8-0.80.40.30.50.20.40.1-0.5-0.5-0.2-0.4-0.6-0.6-0.40.6-0.40.4-0.30.3-0.00.00.9
Bone: endosteal estimation6.916.851.67.2-6.7-6.1-3.8-6.2-5.45.21.25.53.5-2.55.4-1.02.3-5.3-1.3-1.6-1.7-1.3-1.5-1.4-1.3
Bone: endosteal perimeter6.616.249.97.1-6.6-6.0-3.5-6.0-4.75.41.45.53.4-2.75.4-1.12.2-5.3-1.4-1.6-1.8-1.4-1.3-1.5-0.7
Epididymis fat weight2.010.328.6-0.40.0-2.73.6-0.11.60.8-4.82.6-4.1-2.72.5-3.2-3.9-2.4-3.43.7-3.53.84.0-3.7-5.3
Delta time in closed arm before/after self-admin1.51.43.51.1-0.60.1-1.8-0.4-1.5-0.11.5-0.31.41.0-0.31.21.90.31.4-1.61.3-1.5-1.41.20.7
Delta time in open arm before/after self-admin0.60.71.9-0.00.50.7-0.40.6-0.1-0.91.3-0.30.71.2-0.31.40.60.40.7-0.80.7-0.9-1.40.81.4
Diff in mean of infusions in LGA sessions0.71.33.5-1.91.61.21.61.41.9-0.9-1.1-1.0-1.40.0-1.1-0.2-1.01.1-0.10.9-0.11.01.4-0.1-0.9
Delay discount exponential model param0.10.20.7-0.70.40.7-0.20.3-0.4-0.20.1-0.40.10.1-0.4-0.1-0.10.80.00.10.10.0-0.50.30.9
Extinction: sum of active levers before priming0.71.06.00.3-0.6-1.8-0.3-0.6-2.40.6-1.51.1-0.2-0.61.1-0.6-0.6-0.9-0.70.7-0.60.60.0-0.9-1.7
Active lever presses in extinction session 60.20.21.1-0.00.40.5-0.30.5-0.2-0.50.4-0.50.70.9-0.41.10.30.50.3-0.20.4-0.1-0.40.50.6
Bone: final force0.30.41.51.2-0.8-0.9-1.0-0.7-1.20.60.10.70.90.00.60.20.7-0.6-0.0-0.5-0.1-0.4-0.70.1-0.1
Bone: final moment0.30.51.61.2-0.9-0.9-1.0-0.8-1.30.70.10.70.9-0.00.60.10.7-0.6-0.0-0.5-0.1-0.4-0.80.10.0
Food consumed during 24 hour testing period1.32.57.6-2.32.61.71.62.81.6-2.4-1.5-1.8-1.61.0-2.00.4-1.32.00.40.50.60.50.20.7-0.9
Glucose0.10.10.60.4-0.1-0.80.30.2-0.00.20.60.2-0.6-0.00.20.7-0.1-0.2-0.20.1-0.30.10.3-0.3-0.2
Heart weight1.93.17.71.0-1.8-2.10.9-2.10.32.8-1.01.8-0.8-2.71.8-2.3-1.1-1.8-1.91.3-2.01.61.9-2.0-0.8
Delay discount hyperbolic model param0.20.20.9-0.90.50.7-0.20.3-0.4-0.20.1-0.50.10.1-0.5-0.1-0.10.90.10.10.20.0-0.50.40.9
Intermittent access intake day 1-15 change0.00.21.0-0.2-0.10.20.30.01.0-0.20.40.1-0.5-0.10.1-0.1-0.60.2-0.40.9-0.20.70.5-0.4-0.3
Intermittent access intake escalation0.10.31.9-0.50.10.30.60.11.4-0.10.20.0-0.7-0.3-0.0-0.4-0.80.3-0.51.0-0.40.80.7-0.4-0.2
Intermittent access intake escalation 20.10.10.5-0.1-0.00.4-0.30.20.4-0.30.4-0.5-0.10.3-0.50.1-0.10.70.30.30.40.1-0.00.4-0.4
Intermitt. access day 1 inactive lever presses0.22.45.80.9-1.2-1.30.8-1.60.61.2-1.02.1-0.8-1.72.1-1.7-1.2-2.4-2.01.7-2.01.60.9-2.1-0.9
Intermitt. access day 15 inactive lever presses0.10.42.3-0.30.30.40.70.21.5-0.70.20.4-0.80.10.40.1-0.8-0.3-0.61.1-0.60.90.2-0.8-0.8
Intermitt. access escalation Index0.00.10.3-0.10.20.1-0.30.1-0.5-0.2-0.4-0.40.10.1-0.4-0.40.20.40.4-0.60.5-0.4-0.20.4-0.0
Intermittent access day 1 total infusions0.20.51.80.0-0.4-0.50.8-0.60.51.3-0.60.2-0.3-1.30.2-1.0-0.4-0.2-0.90.3-0.90.60.8-0.60.6
Intermittent access day 15 total infusions0.51.12.4-0.5-0.3-0.31.3-0.61.50.9-0.60.4-1.0-1.50.4-1.4-1.2-0.3-1.41.5-1.31.51.5-1.20.0
Intermittent access terminal intake (last 3 days)0.20.30.80.1-0.5-0.10.5-0.50.90.6-0.00.3-0.4-0.80.3-0.7-0.5-0.2-0.60.7-0.60.70.8-0.50.0
Intermittent access total infusions0.91.02.7-0.0-0.6-0.41.2-0.91.41.4-0.50.6-0.6-1.60.6-1.4-0.9-0.5-1.31.1-1.31.21.3-1.10.4
Intermittent access day 1 locomotion0.71.33.10.3-0.7-0.81.1-0.91.21.5-0.80.8-0.7-1.80.8-1.4-1.0-0.8-1.61.2-1.51.41.4-1.3-0.0
Intermittent access day 15 total locomotion0.41.63.90.4-1.1-0.61.1-1.41.71.7-0.20.9-0.7-2.00.9-1.8-1.1-0.9-1.61.3-1.61.51.6-1.40.3
Intermittent access total locomotion2.12.66.5-0.0-0.9-0.81.8-1.22.11.9-1.00.9-1.3-2.50.9-2.3-1.7-0.9-2.11.7-2.02.02.1-1.8-0.0
Intermittent access standard deviation0.21.02.70.1-0.8-0.70.9-0.81.21.00.40.8-0.9-1.20.7-0.6-1.1-0.5-1.21.5-1.21.61.2-1.5-0.6
Left kidney weight0.21.32.4-0.20.0-0.41.6-0.21.50.5-1.50.6-1.2-1.30.6-1.4-1.3-0.6-1.41.4-1.41.41.5-1.2-0.8
Right kidney weight0.21.13.9-0.50.70.01.40.71.6-0.3-2.00.2-1.3-0.60.2-1.0-1.3-0.1-1.01.2-0.91.31.4-0.8-1.1
Cocaine induced anxiety0.20.51.71.0-1.3-0.6-1.0-1.3-0.71.21.00.70.8-0.30.70.20.6-0.7-0.00.2-0.10.20.0-0.40.1
Post-drug Anxiety0.20.21.4-0.0-0.20.5-0.7-0.20.30.21.2-0.30.70.4-0.30.80.50.40.5-0.00.4-0.1-0.20.30.6
Baseline Anxiety0.71.23.2-1.41.71.50.61.80.9-1.7-0.4-1.5-0.41.1-1.50.7-0.31.60.6-0.00.8-0.2-0.31.00.2
Tail length2.413.128.80.8-2.0-3.42.9-2.70.73.3-4.93.8-2.6-4.73.8-5.4-3.5-3.8-4.53.7-4.43.53.6-4.1-3.4
Length with tail2.410.616.61.5-2.3-3.52.3-2.60.52.7-3.23.9-2.3-3.83.9-3.7-3.2-3.9-4.13.5-4.03.33.0-4.0-3.9
Length without tail0.10.84.00.8-0.6-1.10.5-0.20.5-0.0-0.01.1-0.8-0.31.00.2-1.0-1.0-0.91.2-0.91.00.5-1.1-2.0
Times rat made contact with spout0.50.61.5-0.20.10.11.0-0.11.20.3-1.00.5-1.0-0.90.3-1.2-0.9-0.3-0.80.9-0.81.01.2-0.80.2
Lifetime Intake0.81.02.5-0.2-0.4-0.31.3-0.81.41.3-0.50.5-0.5-1.60.5-1.3-1.0-0.5-1.41.1-1.41.21.1-1.10.7
Liver weight, left0.91.64.12.0-1.9-1.6-0.3-2.0-0.62.0-0.51.70.7-1.51.7-1.40.3-1.6-1.00.0-1.10.00.3-0.70.4
Liver weight, right0.30.52.1-0.71.00.31.20.81.0-0.8-1.4-0.5-1.00.0-0.5-0.4-0.70.5-0.20.5-0.20.60.5-0.1-1.0
Locomotor activity0.40.62.1-0.1-0.3-1.00.5-0.5-0.51.3-1.3-0.0-0.5-1.4-0.0-1.4-0.60.1-1.00.7-0.90.70.8-0.5-0.1
Locomotor testing distance0.81.94.6-0.8-0.1-1.01.3-0.50.41.6-1.90.1-1.4-2.20.1-2.1-1.6-0.1-1.81.8-1.81.91.7-1.4-0.1
Locomotor testing rearing1.55.511.2-1.50.3-1.02.8-0.41.71.6-3.30.6-2.8-3.00.6-3.3-3.0-0.5-2.93.1-2.83.33.3-2.6-1.3
Locomotion in novel chamber0.30.41.70.80.0-0.9-0.30.1-1.3-0.7-0.00.9-0.10.80.90.90.3-0.90.1-0.10.0-0.1-0.5-0.3-0.9
Locomotion in novel chamber post-restriction0.41.32.7-0.00.70.9-0.90.9-0.3-1.40.9-1.00.81.6-1.11.41.20.81.4-1.41.5-1.5-1.41.50.8
Fecal boli incidents, locomotor time 10.41.04.81.2-0.90.1-1.3-0.4-0.30.12.2-0.21.40.7-0.21.31.30.21.0-1.31.0-1.2-0.91.00.6
Change in fecal boli incidents, locomotor task0.50.61.7-1.01.00.6-0.11.2-0.4-1.30.0-1.0-0.11.1-1.00.8-0.00.90.7-0.30.8-0.1-0.70.5-0.6
Time >=10cm from walls, locomotor time 10.20.20.7-0.40.40.6-0.10.5-0.1-0.40.7-0.50.40.5-0.50.90.20.40.3-0.40.3-0.3-0.30.40.6
Bouts of movement, locomotor time 10.50.61.5-0.40.0-0.11.0-0.21.10.4-0.90.6-1.0-0.90.7-1.2-0.9-0.6-0.70.6-0.70.81.2-0.8-0.9
Total resting periods, locomotor time 10.20.30.7-0.1-0.1-0.10.5-0.20.70.3-0.50.5-0.6-0.60.6-0.8-0.5-0.5-0.30.3-0.40.50.8-0.5-0.8
Rest time, locomotor task time 10.10.10.50.0-0.00.2-0.10.20.3-0.20.7-0.6-0.10.4-0.60.60.20.50.7-0.20.60.10.10.2-0.1
Distance moved, locomotor task time 10.20.62.0-0.81.00.21.30.80.5-0.8-1.40.2-1.2-0.10.2-0.5-0.90.1-0.60.8-0.70.70.8-0.4-0.8
Vertical activity count, locomotor time 10.10.73.1-1.01.10.31.20.80.6-0.6-1.8-0.0-1.3-0.30.0-0.7-1.10.2-0.71.0-0.60.80.9-0.4-0.8
Time >=10cm from walls, locomotor time 20.41.22.8-1.71.60.61.31.50.9-1.3-1.2-1.2-1.40.3-1.10.0-1.31.2-0.21.0-0.01.00.7-0.2-1.3
Bouts of movement, locomotor time 20.41.44.4-1.51.40.52.01.52.1-1.3-1.2-0.3-1.8-0.1-0.3-0.3-1.60.2-0.60.8-0.40.91.1-0.6-1.3
Total resting periods, locomotor time 20.31.14.5-1.31.30.61.81.42.1-1.3-0.7-0.4-1.70.1-0.4-0.0-1.30.4-0.50.6-0.30.70.9-0.5-1.1
Rest time, locomotor task time 21.32.26.01.1-0.40.3-1.70.1-1.0-0.72.5-0.41.41.7-0.42.22.10.52.0-2.31.9-1.8-1.41.50.9
Distance moved, locomotor task time 22.02.68.3-2.32.31.12.31.81.6-1.5-2.9-0.8-2.1-0.2-0.8-1.1-2.00.7-0.81.9-0.81.71.6-0.9-1.4
Vertical activity count, locomotor time 20.92.29.0-1.81.50.72.01.01.5-0.4-3.0-0.3-1.8-0.9-0.3-1.8-2.00.3-1.32.0-1.21.71.6-1.0-0.9
Light reinforcement 10.52.26.6-2.42.11.81.32.21.8-1.4-0.7-2.5-0.80.5-2.60.2-0.72.50.50.10.60.10.11.00.3
Light reinforcement 20.00.11.1-0.10.1-0.6-0.30.2-1.0-0.00.0-0.10.00.1-0.20.40.2-0.10.0-0.10.0-0.2-0.50.0-0.4
Bone: marrow area6.616.149.67.0-6.5-6.0-3.7-6.0-5.35.11.15.43.4-2.45.3-1.02.3-5.2-1.2-1.5-1.6-1.3-1.5-1.3-1.3
Bone: maximum diameter2.04.014.23.8-3.1-2.6-2.5-2.6-2.72.31.52.02.5-0.61.90.52.0-1.80.2-1.8-0.0-1.7-1.60.30.5
Bone: maximum force0.51.03.51.9-1.6-1.5-1.2-1.3-1.41.50.41.21.2-0.51.10.10.8-1.1-0.4-0.5-0.5-0.4-0.7-0.20.2
Bone: maximum moment0.61.13.41.8-1.6-1.5-1.2-1.4-1.41.50.41.21.2-0.61.1-0.00.8-1.1-0.4-0.4-0.5-0.3-0.7-0.20.2
Mean time between licks in bursts0.10.94.10.4-0.6-1.20.5-0.4-0.10.4-0.60.8-0.8-0.71.0-0.5-1.0-1.0-1.01.2-0.91.20.7-1.3-2.0
Mean num. licks in bursts0.10.32.0-0.70.80.90.60.71.4-0.5-0.0-0.6-0.40.1-0.6-0.1-0.30.5-0.10.20.00.00.50.21.1
Cd content in liver0.60.71.80.00.40.5-0.80.5-0.4-0.91.1-0.70.51.3-0.71.30.80.61.2-0.81.2-0.7-0.80.8-0.2
Co content in liver0.10.10.50.5-0.3-0.3-0.3-0.3-0.1-0.10.30.4-0.10.10.40.00.4-0.20.4-0.50.3-0.4-0.10.1-0.7
Cu content in liver0.30.41.11.1-1.0-0.6-0.8-0.8-0.90.50.90.50.80.10.50.30.8-0.50.3-0.50.2-0.5-0.40.10.2
Fe content in liver0.20.20.70.3-0.7-0.4-0.4-0.9-0.60.70.60.20.5-0.40.2-0.30.1-0.6-0.0-0.1-0.0-0.1-0.6-0.30.1
K content in liver0.90.92.60.7-0.10.7-1.2-0.0-0.4-0.30.9-0.11.40.9-0.10.81.30.20.8-1.30.8-1.3-1.31.11.6
Mg content in liver2.93.25.90.40.51.6-1.90.6-0.5-1.11.7-1.32.12.0-1.31.82.41.32.2-2.42.2-2.4-2.12.42.4
Mn content in liver4.34.89.6-0.61.22.4-1.91.3-0.1-1.42.1-2.52.12.2-2.52.22.32.42.6-2.62.7-2.5-2.42.83.1
Na content in liver0.80.92.1-0.20.71.2-0.50.90.3-1.21.3-0.90.61.4-0.91.40.70.91.0-0.91.1-0.8-0.81.01.0
Rb content in liver0.50.61.3-0.81.01.1-0.11.00.5-1.10.4-1.0-0.11.1-1.00.90.40.90.9-0.30.9-0.2-0.30.60.3
Se content in liver0.30.30.7-0.60.70.7-0.10.70.2-0.50.5-0.80.30.6-0.80.80.20.60.5-0.50.6-0.5-0.80.50.8
Sr content in liver0.10.10.40.6-0.6-0.60.1-0.4-0.00.30.20.3-0.2-0.40.3-0.3-0.2-0.4-0.3-0.0-0.3-0.00.3-0.3-0.5
Zn content in liver1.11.33.21.6-1.4-0.6-1.6-1.3-1.51.01.50.51.80.10.50.51.5-0.50.6-1.30.4-1.3-1.20.71.5
Bone: minimum diameter5.210.029.55.4-5.2-4.9-2.3-4.8-3.44.60.64.32.4-2.54.2-1.31.4-4.2-1.5-0.8-1.8-0.7-0.7-1.4-0.6
Time in familiar zone, hab. session 10.40.51.11.0-0.8-0.8-1.0-0.4-0.90.10.90.30.60.40.30.70.6-0.20.5-0.90.6-0.9-0.70.5-0.6
Time in novel zone, hab. session 10.40.51.2-1.10.71.00.90.41.1-0.1-0.8-0.5-0.3-0.4-0.5-0.7-0.60.5-0.50.8-0.50.70.7-0.10.9
Total zone transitions, hab. session 10.30.51.3-0.90.50.41.00.31.20.0-0.7-0.1-0.7-0.6-0.1-0.8-1.00.2-0.90.9-0.80.80.7-0.50.2
Total locomotion distance, hab. session 10.81.24.4-1.61.21.01.70.92.1-0.5-1.2-0.8-1.2-0.5-0.9-0.9-1.40.6-0.71.0-0.61.21.1-0.50.1
Locomotion velocity, hab. session 10.71.13.1-1.41.10.71.60.81.8-0.4-1.4-0.6-1.3-0.6-0.7-1.0-1.40.4-0.81.1-0.61.21.2-0.7-0.1
Time in familiar zone, hab. session 21.21.43.10.9-1.5-1.8-0.0-1.6-1.01.6-0.71.5-0.0-1.41.5-1.2-0.5-1.5-1.10.7-1.20.70.7-1.2-1.2
Time in novel zone, hab. session 23.43.76.4-1.01.82.5-0.82.00.7-2.11.4-2.31.02.3-2.42.11.42.22.2-1.82.2-1.8-1.82.42.1
Total zone transitions, hab. session 20.10.20.7-0.90.60.30.50.40.3-0.3-0.2-0.4-0.4-0.1-0.5-0.1-0.50.4-0.40.3-0.30.3-0.2-0.10.6
Total locomotion distance, hab. session 21.21.54.7-2.21.91.31.41.81.6-1.4-0.8-1.7-1.30.3-1.7-0.0-1.21.6-0.00.60.10.70.30.10.2
Locomotion velocity, hab. session 21.21.64.7-2.22.01.41.41.91.7-1.4-0.8-1.7-1.30.4-1.70.1-1.11.60.10.50.20.60.30.20.3
Novel to familiar place preference ratio2.73.67.82.0-2.5-2.5-0.2-2.6-1.42.5-0.42.80.1-2.12.8-1.9-0.5-2.8-2.01.1-2.10.90.9-1.8-0.4
Novelty place preference2.22.86.31.9-2.3-2.3-0.3-2.4-1.42.3-0.12.50.1-1.82.5-1.6-0.3-2.5-1.70.9-1.80.70.8-1.6-0.2
Time in novel zone, NPP test2.02.45.31.7-2.1-2.1-0.3-2.3-1.32.1-0.12.30.2-1.72.3-1.6-0.3-2.3-1.60.8-1.70.60.7-1.4-0.1
Total zone transitions, NPP test0.61.03.4-1.51.41.40.61.21.2-0.80.2-1.4-0.20.4-1.40.3-0.21.50.3-0.30.4-0.2-0.60.71.8
Total locomotion distance, NPP test1.72.46.3-2.52.32.31.22.02.3-1.5-0.5-2.4-0.60.7-2.30.2-0.62.30.5-0.00.70.2-0.10.91.6
Locomotion velocity, NPP test1.62.26.7-2.52.32.11.62.02.6-1.4-0.7-2.1-1.10.4-2.10.0-1.02.10.10.40.30.60.30.51.2
Intraocular pressure2.54.19.20.7-1.8-2.31.2-2.2-0.12.9-1.32.1-0.9-3.02.1-2.4-1.8-2.2-2.81.9-2.72.01.7-2.5-0.5
Delta distance traveled before/after self-admin0.20.20.8-0.60.50.4-0.10.4-0.3-0.2-0.2-0.90.10.0-0.8-0.20.10.90.2-0.20.3-0.3-0.40.50.3
Delta ambulatory time before/after self-admin0.30.61.20.1-0.00.4-1.00.2-0.8-0.10.6-1.00.90.5-0.90.40.71.10.9-0.80.9-0.9-1.11.10.5
Parametrial fat weight1.02.44.40.90.10.6-2.10.5-1.6-1.11.4-0.91.82.0-0.92.02.00.82.1-2.02.0-1.9-2.11.90.5
Pavlov. Cond. lever latency1.72.25.00.50.20.9-1.50.5-0.2-0.92.0-0.71.51.8-0.72.11.90.81.8-2.11.7-2.2-1.61.91.2
Pavlov. Cond. magazine entry latency0.40.52.0-0.90.50.20.60.30.30.0-1.4-0.3-0.6-0.5-0.2-0.9-0.90.1-0.71.1-0.61.10.6-0.6-1.0
Pavlov. Cond. change in total contacts1.51.64.0-0.0-0.6-0.90.9-0.90.01.1-1.81.0-0.9-1.61.0-2.0-1.4-1.1-1.71.7-1.61.71.1-1.6-1.1
Pavlov. Cond. index score0.81.02.7-0.5-0.1-0.50.9-0.20.10.6-1.60.4-0.9-1.10.4-1.4-1.3-0.5-1.31.6-1.11.61.0-1.2-1.2
Pavlov. Cond. latency score1.01.33.1-0.5-0.0-0.51.1-0.20.30.5-1.80.5-1.1-1.20.5-1.5-1.5-0.6-1.41.7-1.31.81.2-1.4-1.3
Pavlov. Cond. lever contacts1.11.33.1-0.5-0.1-0.61.2-0.30.30.7-1.60.5-1.2-1.30.5-1.6-1.5-0.6-1.41.7-1.31.81.3-1.5-1.0
Pavlov. Cond. magazine entry number0.30.31.20.5-0.20.0-0.5-0.1-0.1-0.11.10.10.50.40.00.70.80.00.6-1.00.5-1.0-0.50.51.1
Pavlov. Cond. intertrial magazine entries4.65.512.82.3-3.2-3.40.2-3.4-1.13.6-0.33.0-0.0-3.13.0-2.3-0.9-3.0-2.51.3-2.61.21.0-2.5-0.5
Pavlov. Cond. lever-magazine prob. diff.0.50.71.8-0.4-0.1-0.30.7-0.20.10.5-1.30.2-0.6-0.90.3-1.2-1.1-0.3-1.11.4-1.01.30.8-1.0-0.8
Pavlov. Cond. response bias0.30.31.4-0.4-0.0-0.20.3-0.2-0.30.5-1.20.0-0.3-0.60.1-1.0-0.6-0.1-0.60.9-0.50.90.5-0.6-0.7
Pavlov. Cond. lever latency0.40.62.5-0.91.10.40.91.20.5-1.3-0.7-0.4-1.30.5-0.40.3-0.80.40.00.60.10.70.8-0.2-1.6
Pavlov. Cond. magazine entry latency0.10.10.70.2-0.2-0.7-0.1-0.1-0.60.20.40.3-0.2-0.10.20.3-0.1-0.2-0.20.3-0.20.0-0.4-0.3-0.8
Pavlov. Cond. change in total contacts0.20.41.80.6-1.1-0.8-0.6-1.1-0.71.30.40.50.7-0.80.6-0.40.2-0.7-0.50.0-0.5-0.0-0.5-0.40.6
Pavlov. Cond. index score0.50.82.31.2-1.4-1.2-1.0-1.4-1.21.50.70.81.0-0.70.8-0.20.6-0.8-0.3-0.4-0.4-0.5-0.8-0.20.4
Pavlov. Cond. latency score0.40.72.31.1-1.4-1.2-0.8-1.3-1.21.50.60.80.8-0.80.8-0.30.4-0.8-0.4-0.3-0.4-0.4-0.7-0.30.4
Pavlov. Cond. lever contacts0.40.53.00.6-0.80.0-0.9-0.8-0.30.90.8-0.01.3-0.30.0-0.10.8-0.00.2-0.80.2-0.9-0.90.51.7
Pavlov. Cond. magazine entry number0.10.10.60.10.20.8-0.00.10.5-0.4-0.4-0.10.30.3-0.1-0.20.30.10.3-0.30.3-0.20.20.40.6
Pavlov. Cond. intertrial magazine entries0.40.92.30.50.10.7-1.20.3-0.7-0.50.5-0.61.41.0-0.60.81.20.61.2-1.51.1-1.4-1.11.41.2
Pavlov. Cond. lever-magazine prob. diff.0.40.72.11.1-1.3-1.2-0.9-1.3-1.11.40.70.80.9-0.70.8-0.20.5-0.8-0.3-0.3-0.3-0.4-0.7-0.20.3
Pavlov. Cond. response bias0.50.61.80.9-1.0-0.3-1.0-1.0-0.51.01.00.21.3-0.20.20.10.9-0.20.3-0.80.2-0.9-1.00.51.3
Time in closed arm before self-admin0.50.94.2-0.90.3-0.41.20.00.20.7-2.0-0.2-1.1-1.4-0.2-1.8-1.30.2-1.01.0-0.91.00.9-0.7-0.5
Time in closed arm after self-admin0.40.52.1-0.40.1-0.60.7-0.1-0.10.5-1.4-0.1-1.0-0.9-0.0-1.1-0.70.1-0.60.8-0.60.80.7-0.6-1.1
Time in open arm before self-admin0.60.73.8-0.60.4-0.21.00.61.0-0.6-0.20.1-1.20.00.10.2-1.0-0.1-0.61.2-0.51.21.1-0.9-2.0
Time in open arm after self-admin0.20.20.80.3-0.4-0.60.3-0.20.20.00.60.9-0.1-0.10.80.4-0.5-0.8-0.60.5-0.60.40.1-0.7-0.4
Bone: periosteal estimation3.78.826.75.2-4.8-4.5-2.5-4.5-3.54.20.54.02.5-2.23.8-1.11.5-3.8-1.2-1.0-1.6-0.8-1.0-1.1-0.5
Bone: periosteal perimeter2.95.818.14.3-4.0-3.8-1.6-3.6-2.13.50.73.41.5-2.03.3-0.81.0-3.2-1.2-0.6-1.4-0.4-0.3-1.2-0.5
Bone: post-yield work0.91.55.52.4-2.0-1.7-1.2-1.7-1.21.60.91.71.2-0.61.60.20.7-1.5-0.5-0.5-0.7-0.3-0.6-0.40.2
Progressive ratio test 1 active lever presses2.23.98.5-1.40.5-0.22.9-0.02.71.0-2.60.5-2.4-2.40.5-2.6-2.5-0.5-2.32.4-2.22.62.8-2.0-0.8
Progressive ratio test 1 breakpoint2.03.57.5-1.30.5-0.22.7-0.02.51.0-2.60.5-2.2-2.30.5-2.5-2.3-0.5-2.22.2-2.02.42.7-1.8-0.7
Progressive ratio test 1 inactive lever presses0.41.04.4-0.70.60.41.40.32.1-0.1-1.00.3-1.3-0.90.2-1.1-1.2-0.5-1.31.3-1.21.20.8-1.00.4
Progressive ratio test 2 active lever presses1.52.13.9-0.5-0.3-0.72.0-0.71.61.2-1.30.9-1.4-1.90.9-1.8-1.6-0.8-1.91.9-1.82.02.0-1.8-0.6
Progressive ratio test 2 breakpoint1.72.24.0-0.5-0.3-0.72.0-0.81.71.2-1.30.9-1.5-1.90.9-1.8-1.7-0.9-1.91.9-1.92.02.0-1.8-0.7
Progressive ratio test 2 inactive lever presses0.30.91.7-0.1-0.3-0.41.2-0.61.20.9-0.60.7-0.8-1.20.7-1.0-0.9-0.8-1.31.3-1.31.31.0-1.2-0.2
Incentive Sensitization - Responses0.30.81.40.8-1.0-1.10.8-1.00.50.90.11.2-0.4-0.91.2-0.5-0.6-1.2-1.00.7-1.00.70.8-1.1-0.8
Incentive Sensitization - Breakpoint0.30.71.40.8-1.0-1.10.7-1.00.50.90.21.2-0.4-0.91.2-0.5-0.5-1.1-0.90.6-1.00.70.7-1.1-0.8
Sum of active levers in priming session hrs 5-60.30.31.4-0.70.7-0.20.70.60.2-0.5-1.2-0.3-1.0-0.1-0.2-0.4-0.60.2-0.20.4-0.00.40.5-0.2-0.8
Progressive ratio0.30.93.71.3-1.1-1.7-0.8-0.8-1.90.40.61.30.50.21.30.80.2-1.1-0.3-0.0-0.4-0.2-0.5-0.5-1.2
Food seeking constrained by brief footshock0.60.72.01.1-1.1-1.1-1.0-1.2-1.30.80.21.40.6-0.31.4-0.30.3-1.0-0.50.3-0.60.0-0.9-0.5-0.7
Seeking ratio, punishment vs. effort0.10.31.5-0.40.10.60.4-0.20.90.4-0.6-0.1-0.4-0.8-0.0-1.2-0.40.0-0.50.5-0.40.40.3-0.20.4
Retroperitoneal fat weight1.25.312.6-1.30.8-0.82.80.61.9-0.2-3.41.2-3.2-1.71.2-2.4-3.2-1.2-2.43.1-2.43.12.7-2.6-3.5
Reaction time number correct0.31.22.50.10.10.1-1.30.4-1.5-0.11.0-1.11.10.9-1.11.31.31.11.4-1.61.4-1.5-1.11.40.9
Reaction time mean minus median0.10.81.80.00.60.4-0.71.0-1.2-1.3-0.0-0.80.21.3-0.81.10.50.81.3-0.81.2-0.6-0.81.0-1.0
Reaction time mean minus median AUC0.42.44.50.20.60.9-1.71.1-1.7-1.30.9-1.51.52.0-1.41.81.61.52.1-1.92.0-1.7-2.02.10.6
Reaction time num false alarms0.81.44.81.7-2.0-2.2-0.4-1.9-1.32.00.41.30.7-1.31.2-0.60.1-1.2-0.9-0.1-1.0-0.2-0.2-0.6-0.4
Reaction time num false alarms AUC0.61.44.12.0-1.9-1.8-1.2-1.6-1.91.61.00.81.5-0.50.70.20.9-0.8-0.1-1.0-0.1-1.1-1.00.30.2
Reaction time trials correct on left0.31.22.50.10.10.1-1.30.4-1.5-0.11.0-1.11.10.9-1.11.31.31.11.4-1.61.4-1.5-1.11.40.9
Reaction time trials on left0.41.42.80.20.10.2-1.40.4-1.5-0.21.1-1.21.21.0-1.21.41.41.11.5-1.71.5-1.6-1.21.50.9
Reaction time mean0.20.51.0-0.40.80.9-0.60.8-0.7-1.0-0.1-0.70.21.0-0.70.50.50.71.0-0.40.9-0.3-0.60.8-0.2
Reaction time mean AUC0.20.51.1-0.70.91.1-0.40.9-0.5-1.1-0.3-0.70.11.0-0.80.40.40.80.9-0.30.8-0.2-0.40.7-0.2
Median of all reaction times0.20.41.1-0.60.81.1-0.50.7-0.5-0.8-0.1-0.60.20.8-0.60.30.50.60.8-0.30.8-0.2-0.50.70.1
Reaction time omissions1.72.75.3-0.41.21.6-1.41.6-1.0-1.90.6-1.91.42.3-1.81.91.41.92.2-1.62.1-1.5-1.92.20.4
Reaction time false alarm rate0.81.12.91.5-1.7-1.7-0.2-1.6-0.71.50.21.40.5-1.11.4-0.7-0.1-1.4-1.00.3-1.10.1-0.0-0.7-0.6
Reaction time premature initiation rate0.91.53.40.4-0.5-0.81.5-0.61.80.6-0.61.0-1.3-1.31.0-1.2-1.3-1.2-1.61.4-1.61.21.7-1.4-1.0
Reaction time premature initiations0.00.10.50.5-0.4-0.40.3-0.30.70.30.20.2-0.2-0.40.2-0.1-0.2-0.3-0.40.0-0.40.00.5-0.2-0.0
Std. dev. reaction times0.51.84.1-0.10.91.2-1.31.2-1.1-1.60.7-1.20.92.0-1.31.71.31.31.9-1.41.8-1.3-1.51.70.1
Reaction time trials completed0.41.42.80.20.10.2-1.40.4-1.5-0.21.1-1.21.21.0-1.21.41.41.11.5-1.71.5-1.6-1.21.50.9
Reaction time trials AUC0.41.22.40.10.20.2-1.20.5-1.4-0.30.9-1.21.11.1-1.21.41.31.11.4-1.61.5-1.4-1.11.40.8
Run reversals in cocaine runway, females1.92.19.9-1.20.9-0.22.10.91.2-1.0-1.60.3-2.2-0.30.3-0.6-2.2-0.5-1.11.9-0.91.91.6-1.5-3.1
Run reversals in cocaine runway, males1.21.34.91.4-1.3-1.3-0.3-1.4-0.91.2-0.22.10.0-0.82.2-0.70.3-2.1-0.80.3-0.90.30.6-1.1-0.9
Latency to leave start box in cocaine runway2.12.86.9-2.62.41.32.62.12.2-1.5-2.6-1.5-2.4-0.3-1.4-1.0-1.81.1-0.41.2-0.31.31.8-0.4-1.0
Latency to leave start box in cocaine runway, F3.74.712.8-2.51.80.63.41.53.6-0.7-2.7-0.3-3.3-1.3-0.3-1.8-3.0-0.1-1.82.6-1.72.62.7-1.9-1.6
Latency to leave start box in cocaine runway, M2.52.45.8-1.62.01.7-0.12.0-0.7-2.0-0.7-2.40.11.5-2.30.70.62.41.7-1.21.8-1.2-0.91.90.3
Std. dev. time between licks in bursts0.40.71.7-1.21.31.00.81.21.1-1.3-0.2-1.2-0.80.6-1.10.4-0.51.10.30.30.50.60.20.1-0.3
Total sessions with >9 infusions1.41.74.7-1.10.5-0.12.20.12.10.4-1.20.1-1.5-1.40.1-1.2-1.9-0.1-1.71.8-1.61.81.3-1.40.1
Short access day 1 total inactive lever presses0.51.02.2-0.0-0.4-0.41.3-0.61.50.9-0.30.8-0.8-1.20.8-0.9-1.1-0.8-1.41.3-1.41.31.0-1.30.2
Short access day 10 total inactive lever presses0.10.42.41.0-0.4-0.5-1.1-0.3-1.5-0.10.50.50.60.60.50.70.8-0.50.4-0.50.3-0.6-1.00.20.0
Short access day 1 total infusions0.91.84.4-1.40.3-0.32.1-0.11.70.8-1.20.3-1.4-1.60.2-1.4-2.0-0.2-1.91.9-1.71.91.3-1.50.4
Short access day 10 total infusions0.50.92.4-0.30.1-0.21.5-0.21.50.7-0.90.4-0.9-1.30.4-1.2-1.1-0.4-1.41.0-1.41.00.9-0.90.7
Short access total infusions0.60.82.1-0.4-0.3-0.31.2-0.61.11.1-0.60.4-0.5-1.40.4-1.2-1.0-0.5-1.41.0-1.31.00.7-0.91.0
Short access day 1 locomotion3.05.010.0-1.20.3-0.73.2-0.22.91.0-2.71.1-2.6-2.51.1-2.7-3.0-1.1-2.92.9-2.93.02.7-2.5-0.9
Short access day 10 total locomotion0.31.23.40.3-0.9-1.10.8-1.00.31.6-1.10.8-0.8-1.80.8-1.7-0.9-0.6-1.31.1-1.31.11.4-1.1-0.4
Short access total locomotion1.82.86.6-0.90.2-0.32.5-0.12.60.8-1.80.5-1.9-1.90.5-1.8-2.2-0.5-2.22.2-2.02.22.2-1.8-0.4
One hour access (0.3 mA shock)0.30.41.00.6-0.9-0.40.2-0.90.61.00.40.70.2-0.80.7-0.5-0.3-0.7-0.80.4-0.80.40.1-0.60.7
Compulsive drug intake0.40.61.81.3-1.1-0.5-1.0-0.9-1.00.80.60.91.0-0.21.0-0.10.6-0.8-0.2-0.3-0.2-0.5-0.60.00.6
One hour access (shock baseline)0.00.10.6-0.20.10.10.50.00.80.10.1-0.2-0.1-0.1-0.20.1-0.20.1-0.10.2-0.10.30.2-0.20.2
Social response proportion0.60.82.01.1-0.6-0.3-1.4-0.3-1.3-0.10.90.41.41.00.31.31.0-0.50.8-1.00.8-0.9-1.30.6-0.3
Social responses0.40.61.0-0.40.50.9-0.20.70.5-0.80.8-0.90.70.9-1.01.00.30.80.7-0.70.8-0.7-0.90.90.5
Social time1.01.63.91.8-1.2-0.8-1.9-0.8-2.00.41.60.51.60.80.51.41.6-0.61.1-1.61.1-1.5-1.60.80.0
Soleus weight0.51.45.02.0-1.8-2.2-1.1-1.5-2.21.40.41.30.6-0.61.30.00.6-1.1-0.1-0.6-0.2-0.5-0.3-0.3-1.1
Bone: stiffness0.30.62.51.6-0.8-0.8-1.1-0.5-1.00.40.40.71.00.40.80.80.9-0.70.2-0.80.1-0.7-0.80.3-0.4
Tibialis anterior weight0.41.47.10.2-0.3-1.41.0-0.3-0.10.4-1.81.1-1.2-1.11.1-1.1-1.2-1.0-1.21.2-1.11.01.2-1.2-2.7
Time to tail flick, vehicle, before self-admin0.20.20.70.7-0.6-0.1-0.1-0.60.40.30.60.8-0.1-0.00.90.30.2-0.9-0.10.3-0.30.00.3-0.5-0.3
Time to tail flick, vehicle, after self-admin0.30.61.71.3-1.1-1.2-0.9-0.8-1.30.51.10.70.70.20.70.80.8-0.60.3-0.50.1-0.3-0.6-0.1-0.6
Time to tail flick, test, before self-admin2.12.56.72.3-2.6-2.2-0.9-2.6-1.52.20.02.20.8-1.52.1-1.30.5-2.3-0.7-0.3-0.8-0.20.0-0.8-1.2
Time to tail flick, test, after self-admin0.20.30.90.9-0.7-0.1-0.5-0.60.10.40.90.50.80.10.40.40.5-0.50.1-0.50.1-0.4-0.50.20.6
Delta time to tail flick, vehicle, before/after SA0.70.81.70.7-0.10.3-1.00.3-0.3-0.61.2-0.41.11.1-0.41.21.10.51.1-1.31.0-1.0-1.21.10.7
Delta time to tail flick, test, before/after SA0.30.31.6-0.10.20.6-0.40.30.3-0.41.2-0.40.50.7-0.41.00.30.60.4-0.40.4-0.3-0.40.41.3
Tibia length1.74.88.00.3-1.0-2.02.0-1.30.81.4-2.32.2-2.1-2.42.2-2.5-2.3-1.9-2.72.7-2.72.82.5-2.8-2.8
Ambulatory time before self-admin0.20.61.6-1.11.00.11.10.90.6-1.0-1.0-0.0-1.30.3-0.10.1-0.9-0.1-0.30.9-0.20.90.9-0.6-1.2
Ambulatory time after self-admin0.20.31.0-0.90.90.20.20.9-0.3-1.0-0.6-0.6-0.50.6-0.60.2-0.30.60.20.20.40.2-0.20.1-0.9
Bone: tissue strength1.21.33.1-1.41.31.70.31.31.1-1.21.1-1.7-0.11.0-1.71.0-0.01.70.7-0.20.8-0.2-0.30.91.7
Total heroin consumption0.70.81.70.00.80.9-0.41.0-0.1-1.20.3-0.90.51.3-1.01.20.81.01.1-0.91.2-0.8-0.71.10.4
Bone: trabecular number2.85.312.41.2-0.51.5-3.0-0.2-1.3-0.33.0-1.33.52.1-1.22.43.11.22.5-2.92.4-3.0-3.02.83.3
Bone: trabecular spacing2.33.38.4-1.20.8-0.82.50.41.4-0.1-2.50.7-2.9-1.50.7-1.9-2.5-0.9-1.82.3-1.72.52.5-2.2-2.2
Bone: trabecular thickness1.42.05.12.2-1.8-0.8-2.0-1.6-1.71.41.50.42.20.00.50.61.9-0.50.7-1.60.6-1.7-1.41.01.4
Bone: trabecular tissue density0.81.43.1-1.81.60.81.61.61.4-1.2-1.0-1.1-1.80.2-1.2-0.0-1.21.1-0.01.00.11.21.4-0.4-1.3
Water consumed over 24 hours1.73.28.4-2.42.72.50.92.81.4-2.6-0.3-2.5-0.81.6-2.91.0-0.42.91.2-0.21.4-0.1-0.31.50.8
Number of responses in last shaping day0.81.12.7-1.30.70.21.60.31.5-0.1-0.80.0-1.5-0.7-0.0-0.7-1.40.1-1.11.7-1.01.61.2-1.1-0.3