Hub : Genes

Map2k6

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 NAcc mRNA stability Map2k6 0.09 0.04 4.8e-09 0.07 0.08 0.07 0.08 4.7e-09 5.7e-10 1.1e-08 2.6e-09
2 PL mRNA stability Map2k6 0.14 0.05 9.2e-13 0.12 0.12 0.13 0.13 2.0e-13 2.2e-13 3.1e-14 6.4e-14
3 Brain isoform ratio XM_039085033.1 0.07 0.04 2.0e-04 0.02 0.03 0.01 0.02 7.3e-03 1.1e-03 2.1e-02 4.6e-03
4 OFC gene expression Map2k6 0.42 0.12 6.7e-08 0.2 0.3 0.28 0.24 2.2e-05 1.0e-07 2.0e-07 2.6e-06
5 pVTA gene expression Map2k6 0.07 0.04 9.3e-03 0.01 0.04 -0.01 0 1.7e-01 1.2e-02 8.8e-01 2.9e-01
6 IL gene expression Map2k6 0.22 0.09 4.4e-04 0.01 0.05 0.03 0.04 2.1e-01 2.3e-02 5.7e-02 4.6e-02
7 IL mRNA stability Map2k6 0.13 0.07 5.1e-03 0.08 0.05 0.07 0.06 5.7e-03 2.9e-02 1.1e-02 1.4e-02
8 Brain alternative TSS XM_039085033.1 0.04 0.03 4.3e-03 0.01 0.01 0.01 0.01 1.8e-02 2.2e-02 2.8e-02 3.3e-02
9 Brain alternative TSS XM_039085034.1 0.04 0.03 3.3e-03 0.01 0.01 0.01 0.01 1.9e-02 2.1e-02 2.0e-02 3.4e-02
10 Brain mRNA stability Map2k6 0.19 0.06 0.0e+00 0.14 0.18 0.18 0.19 6.7e-13 4.2e-16 5.3e-17 2.8e-17
11 BLA gene expression Map2k6 0.17 0.06 6.5e-11 0.12 0.2 0.18 0.18 3.4e-07 1.1e-10 6.0e-10 7.6e-10
12 PL gene expression Map2k6 0.18 0.06 0.0e+00 0.18 0.19 0.19 0.19 1.5e-19 7.6e-21 1.9e-20 7.3e-21
13 Brain gene expression Map2k6 0.62 0.09 0.0e+00 0.3 0.48 0.47 0.48 2.7e-28 3.1e-50 5.4e-48 2.7e-50
14 IL intron excision ratio chr10_95373426_95448972 0.18 0.09 6.5e-04 0.12 0.18 0.17 0.16 7.6e-04 5.2e-05 8.0e-05 1.4e-04
15 NAcc gene expression Map2k6 0.11 0.04 2.3e-11 0.09 0.1 0.09 0.09 6.5e-11 3.8e-12 9.3e-11 6.6e-11
16 Brain alternative TSS XM_039085033.1 0.21 0.07 0.0e+00 0.12 0.21 0.21 0.22 5.8e-11 3.4e-19 4.0e-19 8.6e-20
17 Brain intron excision ratio chr10_95373426_95448972 0.18 0.07 7.1e-14 0.07 0.15 0.13 0.14 2.4e-07 5.7e-14 3.6e-12 4.3e-13
18 Brain intron excision ratio chr10_95447514_95448972 0.14 0.05 1.1e-12 0.07 0.14 0.12 0.13 5.5e-07 3.4e-13 2.8e-11 3.4e-12
19 Liver alternative TSS XM_039085034.1 0.04 0.03 8.6e-03 0.01 0.01 0.01 0.01 3.9e-02 2.3e-02 1.9e-02 1.6e-02
20 PL intron excision ratio chr10_95447514_95448972 0.24 0.07 0.0e+00 0.34 0.34 0.34 0.34 1.0e-38 6.6e-39 1.3e-38 4.9e-39
21 PL intron excision ratio chr10_95373426_95448972 0.24 0.07 0.0e+00 0.35 0.35 0.35 0.35 7.2e-40 1.2e-39 1.4e-39 6.8e-40
22 Liver alternative TSS XM_039085033.1 0.04 0.03 7.6e-03 0.01 0.01 0.01 0.01 4.6e-02 2.3e-02 2.0e-02 9.6e-03
23 PL alternative TSS NM_053703.3 0.1 0.04 2.8e-15 0.17 0.15 0.17 0.17 2.0e-18 5.6e-16 7.7e-18 5.7e-18
24 PL alternative TSS XM_039085033.1 0.13 0.05 0.0e+00 0.22 0.19 0.21 0.21 6.0e-24 4.3e-20 6.9e-23 6.3e-23
25 Adipose mRNA stability Map2k6 0.04 0.03 1.3e-03 0.01 0.01 0.01 0.01 5.4e-02 1.1e-02 6.2e-02 3.9e-02
26 Brain alternative TSS NM_053703.3 0.19 0.06 0.0e+00 0.14 0.19 0.19 0.2 2.1e-13 8.6e-18 3.6e-17 5.4e-18
27 RMTg gene expression Map2k6 0.2 0.09 1.6e-04 0.13 0.11 0.1 0.1 2.8e-04 5.8e-04 1.5e-03 1.6e-03

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27
Bone: apparent density3.15.111.61.4-2.0-0.1-1.6-3.3-0.7-3.4-0.60.61.0-3.30.5-1.5-3.3-2.51.7-2.22.31.43.2-3.3-1.53.0-3.0-1.6-2.53.1
Area under the delay curve0.30.31.20.4-0.4-0.3-0.0-0.4-0.5-0.21.1-1.10.3-0.2-0.5-0.3-0.10.3-0.60.9-0.8-0.8-0.30.40.8-0.20.20.20.20.1
BMI with tail4.113.227.40.30.8-2.21.43.3-1.34.03.5-3.50.63.8-3.10.44.23.0-4.65.0-5.0-3.4-4.84.73.4-5.25.23.54.9-3.5
BMI without tail4.08.315.22.4-1.0-3.60.71.2-2.41.83.9-3.92.02.3-3.5-1.22.91.1-3.43.7-3.9-2.8-3.33.32.8-3.63.63.03.5-2.1
Body weight5.020.741.01.30.3-3.80.63.1-2.52.95.0-5.01.54.2-4.7-0.04.83.4-5.96.4-6.4-4.5-6.05.94.5-6.26.24.56.4-5.2
Weight adjusted by age2.32.66.2-0.30.7-0.5-0.31.6-0.51.61.4-1.40.01.4-1.50.51.51.4-2.42.5-2.4-1.9-2.02.01.9-1.61.62.12.5-1.8
Bone surface4.17.118.93.4-3.6-2.2-3.3-4.3-2.5-4.21.2-1.22.8-4.2-1.2-3.1-3.8-3.30.3-0.81.00.13.1-3.1-0.22.8-2.8-0.2-1.52.8
Bone volume3.56.017.33.0-3.3-1.9-2.7-4.2-2.3-4.01.1-1.12.6-3.9-1.1-2.9-3.6-2.80.2-0.60.8-0.22.8-2.90.12.5-2.5-0.4-1.42.7
Breakpoint value in progressive ratio session0.30.32.5-0.10.60.20.50.70.71.6-0.40.4-0.80.10.10.80.80.5-0.20.6-0.40.7-0.40.4-0.7-0.20.2-0.60.40.5
Number of licking bursts0.60.71.61.2-0.9-1.2-1.1-0.5-1.1-0.31.1-1.11.1-0.4-1.3-0.8-0.1-0.4-0.81.0-0.9-0.7-0.30.30.7-0.60.60.80.8-0.3
Context. condit. distance diff. score0.10.10.4-0.60.30.60.50.50.30.20.2-0.2-0.40.60.30.30.40.5-0.10.1-0.1-0.0-0.30.30.0-0.40.40.10.1-0.2
Locomotion velocity, session 10.00.10.2-0.10.40.00.40.20.30.2-0.50.5-0.10.10.10.10.20.20.20.0-0.00.20.1-0.1-0.20.1-0.1-0.2-0.10.4
Locomotion distance, session 11.62.05.1-2.32.11.92.20.91.90.5-2.22.2-2.00.81.91.90.51.81.2-0.80.80.60.1-0.1-0.60.4-0.4-1.8-0.60.3
Locomotion velocity, session 20.60.72.3-0.81.30.40.70.30.90.1-1.51.5-1.10.41.11.20.30.61.0-1.11.0-0.10.3-0.30.10.6-0.6-0.8-0.7-0.1
Locomotion distance, session 21.92.77.5-2.22.12.02.00.62.10.5-2.72.7-2.00.32.21.80.11.31.8-1.51.51.00.8-0.8-1.01.1-1.1-2.3-1.30.9
Locomotion velocity, session 32.22.56.9-2.62.51.82.42.02.21.9-1.61.6-2.31.52.02.21.42.10.5-0.30.31.0-0.60.7-0.9-0.20.2-1.2-0.0-0.6
Locomotion distance, session 30.50.51.4-1.00.61.20.3-0.10.8-0.3-1.11.1-0.7-0.51.00.4-0.70.20.6-0.70.80.60.6-0.6-0.60.8-0.8-0.8-0.50.9
Stereotopy head waving bouts, day 32.42.86.1-2.01.52.41.91.02.41.5-1.91.9-1.90.42.51.70.50.61.8-1.41.52.21.0-1.0-2.21.4-1.4-2.2-1.50.8
Stereotopy head waving duration, day 30.50.61.5-0.80.70.90.60.61.11.0-0.90.9-0.90.21.20.70.3-0.00.7-0.80.71.10.6-0.6-1.10.8-0.8-0.6-0.70.2
Locomotion velocity, session 70.60.61.3-0.50.40.70.1-0.40.7-0.3-1.11.1-0.6-0.61.10.5-0.6-0.10.9-1.01.00.50.9-0.9-0.50.9-0.9-1.0-1.10.9
Locomotion distance, session 70.20.21.1-0.40.10.40.3-0.80.1-1.1-0.40.4-0.1-0.60.40.2-0.80.40.1-0.20.30.00.4-0.4-0.00.4-0.4-0.9-0.30.4
Stereotopy head waving bouts, day 70.80.92.60.1-0.10.4-0.40.10.60.6-0.80.8-0.2-0.40.7-0.0-0.4-1.41.2-1.61.41.61.1-1.1-1.61.2-1.2-0.1-1.21.0
Stereotopy head waving duration, day 71.51.84.80.2-0.10.6-0.8-0.10.80.5-1.41.4-0.3-0.91.1-0.2-0.8-1.91.7-2.22.01.91.7-1.7-1.91.8-1.8-0.3-1.81.5
Locomotion velocity, session 80.30.30.9-0.40.80.10.10.40.20.2-0.40.4-0.70.40.20.70.41.0-0.20.5-0.4-0.9-0.90.90.9-0.70.7-0.00.4-0.6
Locomotion distance, session 81.21.74.5-2.11.81.92.10.81.80.5-1.91.9-1.80.81.91.70.41.51.1-1.11.00.50.3-0.3-0.40.5-0.5-1.6-0.80.5
Degree of sensitization distance0.10.10.30.2-0.1-0.30.4-0.4-0.3-0.30.2-0.20.20.1-0.10.00.10.4-0.10.4-0.3-0.3-0.10.00.3-0.20.2-0.4-0.0-0.6
Degree of sensitization stereotypy0.30.32.00.8-0.5-0.5-0.90.1-0.20.4-0.20.20.4-0.2-0.2-0.6-0.2-1.40.3-1.00.70.60.5-0.5-0.60.5-0.50.9-0.40.6
Conditioned locomotion0.10.10.40.6-0.7-0.60.3-0.5-0.40.00.5-0.50.6-0.1-0.3-0.6-0.1-0.20.10.0-0.1-0.00.2-0.20.00.0-0.0-0.2-0.10.3
Cocaine response after cond. corrected1.11.32.91.5-1.7-1.3-1.1-1.4-1.7-1.21.5-1.51.7-0.8-1.3-1.6-0.8-0.7-1.11.0-0.9-1.10.2-0.21.10.0-0.00.90.5-0.5
Cocaine response after cond. not corrected2.02.24.82.0-2.1-1.9-1.6-1.4-2.2-1.32.2-2.22.1-0.9-1.8-2.0-0.8-1.0-1.61.3-1.3-1.2-0.10.11.2-0.30.31.50.9-0.6
Cocaine response before conditioning0.20.20.60.4-0.3-0.6-0.10.4-0.30.30.6-0.60.30.2-0.5-0.40.3-0.2-0.80.4-0.50.1-0.50.5-0.1-0.70.70.80.6-0.0
Saline control response2.43.211.3-2.12.10.93.42.31.62.1-0.30.3-1.62.50.91.82.63.1-0.61.5-1.4-0.1-1.91.90.1-1.81.8-1.01.2-1.6
Bone: connectivity density2.94.69.60.9-1.30.1-1.1-2.70.0-2.8-1.01.00.2-2.81.2-0.7-2.6-2.12.1-2.42.62.23.0-3.0-2.33.1-3.1-2.2-2.52.8
Bone: cortical apparent density3.95.212.0-3.53.13.03.42.93.12.4-2.52.5-3.12.72.43.02.22.41.7-1.00.91.9-1.01.0-1.9-0.60.6-1.9-0.6-1.0
Bone: cortical area0.71.02.80.00.1-1.01.70.2-0.50.11.1-1.10.30.8-0.7-0.11.01.6-1.51.7-1.6-1.1-0.90.91.1-0.80.8-0.11.4-0.9
Bone: cortical porosity2.02.26.22.5-2.2-2.4-1.8-1.6-2.1-1.72.0-2.02.1-1.2-1.7-1.8-1.0-1.8-0.90.1-0.2-0.80.7-0.70.80.2-0.21.40.10.6
Bone: cortical porosity2.73.07.62.7-2.4-2.7-1.9-1.5-2.5-1.72.5-2.52.5-1.1-2.3-2.1-0.8-1.6-1.61.0-1.1-1.20.2-0.21.2-0.40.41.90.80.2
Bone: cortical thickness5.99.731.9-4.74.43.05.64.43.74.0-2.02.0-4.04.52.64.04.04.50.30.3-0.51.1-2.22.3-1.0-1.61.6-1.70.8-2.4
Bone: cortical thickness2.52.911.7-2.51.92.23.41.72.41.9-1.41.4-2.11.62.11.91.41.61.2-0.80.82.10.1-0.1-2.10.4-0.4-2.1-0.80.0
Bone: cortical tissue density3.64.810.9-3.33.02.93.22.83.02.3-2.42.4-2.92.62.32.92.22.21.7-1.00.81.9-1.01.0-1.8-0.60.6-1.8-0.6-1.0
Condit. Reinf. active minus inactive responses1.01.12.71.0-0.8-1.4-0.60.1-1.30.11.6-1.61.10.4-1.4-0.90.4-0.1-1.21.2-1.3-0.8-1.00.90.8-1.21.21.61.3-0.7
Condit. Reinf. active-inactive response ratio0.30.31.11.0-1.1-0.6-0.7-0.3-0.7-0.20.8-0.80.9-0.3-0.7-1.0-0.2-1.0-0.00.3-0.30.50.1-0.2-0.5-0.30.30.6-0.00.3
Condit. Reinf. active responses0.91.12.50.9-0.7-1.5-0.4-0.0-1.30.11.4-1.41.20.4-1.3-1.00.4-0.0-1.41.1-1.3-1.2-0.80.81.2-0.90.91.61.3-0.8
Condit. Reinf. inactive responses0.60.72.60.5-0.2-1.10.2-0.2-1.00.20.7-0.70.90.3-1.0-0.70.20.5-1.31.0-1.1-1.6-0.60.61.6-0.30.31.01.1-0.6
Incentive salience index mean0.10.20.50.5-0.5-0.7-0.30.0-0.50.30.7-0.70.60.1-0.5-0.60.2-0.3-0.30.3-0.4-0.1-0.10.10.1-0.10.10.70.4-0.1
Condit. Reinf. lever presses0.20.21.1-0.60.60.50.50.70.71.1-0.50.5-0.50.50.60.40.50.30.3-0.20.20.40.2-0.3-0.30.5-0.5-0.10.0-0.0
Condit. Reinf. active minus inactive responses2.63.38.92.6-2.3-3.0-1.7-1.6-2.8-2.22.3-2.32.4-0.8-2.3-2.3-0.8-1.3-1.90.9-1.1-1.7-0.40.41.7-0.70.72.11.4-0.0
Condit. Reinf. active-inactive response ratio2.72.96.82.3-2.2-2.5-2.3-1.5-2.6-2.42.1-2.12.3-0.8-2.1-2.0-1.0-1.5-1.50.4-0.7-1.4-0.30.31.4-0.50.52.31.1-0.2
Condit. Reinf. active responses1.21.75.21.8-1.7-2.3-0.6-1.7-2.0-2.11.5-1.51.7-0.8-1.6-1.7-0.8-0.5-1.30.6-0.7-1.4-0.10.11.4-0.20.20.90.90.4
Condit. Reinf. inactive responses0.30.43.3-0.60.70.11.80.00.60.2-0.70.7-0.70.20.60.40.41.10.10.1-0.00.10.2-0.2-0.00.3-0.3-1.3-0.10.5
Condit. Reinf. lever presses0.30.41.30.6-0.4-1.20.9-0.2-0.6-0.30.7-0.70.50.5-0.5-0.50.60.6-0.60.7-0.8-0.8-0.50.60.8-0.40.40.20.8-0.2
Condit. Reinf. lever reinforcers received1.01.54.41.6-1.6-2.1-0.3-1.4-1.9-1.91.5-1.51.6-0.5-1.6-1.6-0.6-0.3-1.30.7-0.8-1.3-0.20.21.3-0.30.30.81.00.2
Conditioned reinforcement - actives1.31.33.81.2-1.4-0.4-1.0-1.3-0.4-0.9-0.50.50.6-1.60.5-1.1-1.4-1.90.7-1.21.21.21.4-1.3-1.21.4-1.4-0.2-1.21.4
Conditioned reinforcement - inactives0.20.21.1-0.1-0.10.10.0-0.7-0.1-0.8-0.10.10.0-0.40.30.0-0.70.10.2-0.30.3-1.10.6-0.61.10.5-0.5-0.2-0.40.4
Conditioned locomotion0.60.71.70.8-0.8-1.3-0.9-0.8-1.2-1.31.1-1.10.7-0.3-1.0-0.5-0.40.0-1.00.8-0.8-1.0-0.70.81.0-0.80.80.80.7-0.4
Patch foraging indifference point 0 sec1.82.87.2-0.71.3-0.92.31.3-0.20.70.9-0.9-0.72.4-0.71.22.22.7-1.31.6-1.8-1.9-2.32.31.9-2.22.20.31.8-2.3
Patch foraging indifference point AUC0.30.30.9-0.61.00.20.70.80.50.7-0.00.0-0.40.90.10.80.80.90.00.3-0.4-0.4-0.70.70.4-0.50.50.00.2-0.8
Delay disc. indifference point, 0s delay0.10.10.5-0.60.30.7-0.10.00.3-0.40.3-0.3-0.2-0.10.20.3-0.30.10.4-0.20.20.7-0.10.2-0.7-0.10.1-0.2-0.40.3
Delay disc. indifference point, 16s delay1.01.02.61.6-1.2-1.3-0.6-0.4-1.20.21.2-1.21.1-0.4-1.3-1.30.1-0.4-1.21.5-1.3-1.2-0.50.51.1-0.60.60.90.80.1
Delay disc. indifference point, 2s delay0.20.21.0-0.70.40.60.7-0.30.3-0.80.0-0.0-0.5-0.00.30.5-0.30.90.50.00.1-0.2-0.10.10.2-0.10.1-1.0-0.40.4
Delay disc. indifference point, 24s delay2.12.05.82.4-2.2-2.0-1.5-1.3-1.9-1.11.6-1.62.3-1.2-1.8-2.3-0.8-1.6-1.20.9-0.9-0.50.4-0.30.50.4-0.41.40.40.5
Delay disc. indifference point, 4s delay0.20.21.1-0.30.20.20.50.10.20.01.1-1.1-0.30.40.00.70.30.80.10.4-0.3-0.5-0.40.40.5-0.50.5-0.4-0.1-0.2
Delay disc. indifference point, 8s delay0.60.61.4-1.21.11.11.11.01.01.10.1-0.1-1.00.80.71.10.81.2-0.10.5-0.30.3-0.60.7-0.3-0.10.1-0.50.0-0.1
Indifference point function ln k0.10.20.60.1-0.2-0.20.6-0.40.1-0.3-0.40.4-0.1-0.30.5-0.2-0.4-0.20.3-0.60.60.10.7-0.7-0.10.6-0.6-0.4-0.50.8
Indifference point function log k0.10.20.60.1-0.2-0.20.6-0.40.1-0.3-0.40.4-0.1-0.30.5-0.2-0.4-0.20.3-0.60.60.10.7-0.7-0.10.6-0.6-0.4-0.50.8
Patch foraging total patch changes 0 sec1.82.87.8-0.81.3-0.82.51.3-0.10.80.8-0.8-0.72.5-0.61.22.32.8-1.21.7-1.8-1.9-2.32.31.9-2.22.20.11.7-2.2
Patch foraging total patch changes 12 sec0.91.24.2-1.11.20.12.00.90.40.60.5-0.5-0.91.60.01.21.42.0-0.60.8-0.9-0.7-1.31.30.7-1.21.2-0.41.0-1.3
Patch foraging total patch changes 18 sec1.92.45.4-1.31.90.02.02.00.61.6-0.00.0-0.82.3-0.21.32.12.3-0.91.3-1.4-1.2-2.12.11.3-2.22.20.41.4-1.9
Patch foraging total patch changes 24 sec0.91.12.80.30.1-1.21.20.1-0.7-0.20.7-0.70.31.0-1.2-0.10.91.3-1.11.3-1.4-1.7-1.21.21.7-1.21.20.41.1-1.2
Patch foraging total patch changes 6 sec3.04.410.0-0.21.1-1.61.11.7-0.80.71.8-1.8-0.22.7-1.50.72.52.2-2.12.1-2.4-2.2-3.13.12.2-3.23.21.82.5-3.0
Patch foraging time to switch 0 sec0.30.52.80.8-0.9-0.1-1.7-0.9-0.6-0.70.3-0.30.6-1.2-0.6-0.7-1.1-1.2-0.1-0.20.30.50.7-0.7-0.50.5-0.50.1-0.10.8
Patch foraging water rate 0 sec1.52.55.8-0.10.5-1.11.81.5-0.31.31.5-1.5-0.02.4-0.90.52.41.8-1.41.7-1.9-1.1-2.22.21.1-2.02.00.91.9-2.1
Patch foraging water rate 12 sec1.72.56.6-1.31.70.32.22.00.92.0-0.10.1-1.32.20.31.42.42.6-0.61.6-1.5-0.6-2.22.30.6-2.12.1-0.21.3-1.7
Patch foraging water rate 18 sec0.40.52.0-0.80.20.81.20.50.80.2-0.40.4-0.70.61.00.50.40.20.9-0.80.71.40.1-0.0-1.4-0.00.0-0.7-0.70.3
Patch foraging water rate 24 sec0.40.62.0-0.90.61.01.40.41.00.5-0.90.9-0.60.31.30.30.20.40.8-0.60.60.80.4-0.3-0.80.4-0.4-1.0-0.70.9
Patch foraging water rate 6 sec0.50.73.7-0.80.70.91.90.91.11.0-0.30.3-1.01.11.00.91.21.00.6-0.00.11.2-0.30.4-1.2-0.10.1-1.1-0.20.1
Seeking ratio, delayed vs. immediate footshock3.74.29.50.90.2-2.0-0.91.6-1.51.32.5-2.51.11.7-2.3-0.51.80.5-3.02.7-2.8-1.6-2.42.41.6-2.22.23.12.9-2.7
Distance traveled before self-admin0.30.31.00.2-0.30.1-0.70.2-0.5-0.00.7-0.70.30.1-0.8-0.3-0.1-0.1-0.80.5-0.5-0.6-0.50.50.6-1.01.01.00.6-0.1
Distance traveled after self-admin0.10.10.50.0-0.30.4-0.40.3-0.00.40.3-0.3-0.0-0.0-0.2-0.2-0.0-0.1-0.20.2-0.2-0.2-0.20.20.2-0.70.70.60.10.3
Extensor digitorum longus weight0.51.94.3-0.50.8-0.1-0.61.7-0.01.61.3-1.3-0.31.1-0.80.61.31.0-1.92.1-1.9-0.7-1.91.90.7-1.91.91.71.9-1.8
Bone: elastic displacement1.01.12.6-1.41.21.31.60.91.41.0-1.51.5-1.30.81.31.10.40.41.0-1.51.20.60.5-0.5-0.60.3-0.3-0.7-1.00.4
Bone: elastic work0.20.33.0-0.50.40.31.70.50.60.6-0.20.2-0.40.60.20.40.60.70.1-0.10.10.30.2-0.2-0.30.1-0.1-0.7-0.00.2
Bone: endosteal estimation10.322.454.17.4-6.7-6.6-6.0-5.8-6.7-5.75.6-5.66.9-4.7-6.0-6.2-3.7-3.9-3.73.1-2.8-3.90.9-1.03.80.3-0.33.41.91.2
Bone: endosteal perimeter9.820.246.36.8-6.1-6.4-5.3-5.5-6.4-5.55.3-5.36.4-4.5-5.5-6.0-3.5-3.3-3.83.3-2.9-4.30.8-0.94.20.1-0.13.21.91.1
Epididymis fat weight3.17.317.60.10.4-1.21.02.4-0.82.63.0-3.00.52.8-2.40.33.32.4-3.34.2-4.0-1.7-3.53.51.7-3.73.72.03.8-3.4
Delta time in closed arm before/after self-admin1.01.03.40.5-1.00.1-1.2-1.2-0.5-1.8-0.30.30.8-1.10.1-1.1-1.6-1.50.8-1.31.20.71.2-1.2-0.71.0-1.0-0.0-1.10.6
Delta time in open arm before/after self-admin1.61.63.4-0.70.31.30.7-0.71.1-0.2-1.91.9-0.8-0.91.40.4-0.9-0.11.6-1.41.50.61.6-1.6-0.61.7-1.7-1.8-1.51.7
Diff in mean of infusions in LGA sessions0.70.71.5-0.60.5-0.10.31.10.10.70.9-0.9-0.21.0-0.30.51.11.0-1.11.2-1.2-0.1-1.21.20.1-1.01.00.61.2-1.0
Delay discount exponential model param0.30.41.4-0.60.60.50.10.60.70.5-1.21.2-0.50.30.70.50.2-0.20.7-0.90.71.00.2-0.2-1.00.1-0.1-0.2-0.2-0.1
Extinction: sum of active levers before priming2.72.710.13.2-2.4-2.3-1.9-1.3-2.1-0.11.5-1.52.6-1.4-2.4-2.6-0.6-2.1-1.31.1-1.0-0.40.0-0.00.4-1.01.01.51.01.0
Active lever presses in extinction session 60.30.32.6-0.10.20.50.9-0.60.4-0.5-0.90.9-0.5-0.50.30.3-0.20.70.30.3-0.00.30.3-0.3-0.3-0.40.4-1.6-0.10.9
Bone: final force0.60.92.81.4-1.7-1.2-0.1-1.3-1.2-1.21.5-1.51.4-0.7-1.1-1.4-0.4-0.3-0.91.0-0.8-0.40.3-0.30.30.3-0.30.00.60.4
Bone: final moment0.60.92.81.4-1.7-1.2-0.1-1.2-1.2-1.11.6-1.61.4-0.7-1.1-1.3-0.4-0.4-0.80.9-0.7-0.40.5-0.40.30.4-0.40.20.50.4
Food consumed during 24 hour testing period1.72.15.5-1.81.91.42.31.82.22.3-1.41.4-1.81.31.61.91.71.51.00.00.11.4-0.10.1-1.40.1-0.1-1.8-0.3-0.5
Glucose0.20.21.4-0.5-0.10.30.00.2-0.2-0.00.4-0.40.5-0.0-0.3-0.5-0.10.6-0.91.2-1.0-0.2-0.40.50.2-0.40.40.40.7-0.4
Heart weight3.65.011.20.9-0.8-2.4-1.00.1-2.5-1.02.8-2.81.71.0-2.6-1.20.50.9-3.32.5-2.7-3.3-2.12.23.3-2.52.53.02.9-2.2
Delay discount hyperbolic model param0.30.31.5-0.40.40.3-0.10.40.50.4-1.21.2-0.30.10.50.20.1-0.50.5-0.90.80.90.3-0.3-0.90.2-0.2-0.1-0.20.0
Intermittent access intake day 1-15 change0.50.52.0-1.31.20.80.60.80.70.1-0.60.6-1.11.00.51.40.61.20.2-0.20.1-0.3-0.70.70.3-0.50.5-0.30.2-0.5
Intermittent access intake escalation0.30.31.3-1.10.91.00.30.60.6-0.2-0.70.7-0.90.60.51.20.20.80.3-0.40.3-0.2-0.40.30.2-0.30.3-0.30.0-0.3
Intermittent access intake escalation 20.20.20.6-0.60.20.60.10.10.3-0.6-0.20.2-0.30.40.30.70.00.10.7-0.60.50.7-0.20.1-0.7-0.00.0-0.4-0.3-0.2
Intermitt. access day 1 inactive lever presses0.80.92.8-0.21.0-0.70.80.2-0.2-0.4-0.00.0-0.61.1-0.61.21.01.6-0.20.5-0.6-1.7-1.21.21.7-1.21.2-0.20.8-1.0
Intermitt. access day 15 inactive lever presses0.50.62.8-1.31.40.80.40.80.90.2-0.50.5-1.10.80.41.70.61.30.4-0.20.2-0.5-0.60.50.5-0.60.6-0.40.2-0.4
Intermitt. access escalation Index0.50.42.01.0-0.8-0.5-0.7-0.4-0.4-0.2-0.10.10.8-0.3-0.3-0.7-0.3-1.40.6-1.00.80.40.8-0.8-0.40.7-0.70.6-0.60.5
Intermittent access day 1 total infusions0.10.10.40.10.1-0.70.60.2-0.10.30.4-0.4-0.10.20.4-0.10.40.2-0.70.5-0.5-0.0-0.30.30.00.1-0.10.20.2-0.5
Intermittent access day 15 total infusions0.10.10.5-0.60.60.10.40.40.30.0-0.30.3-0.60.50.50.70.30.6-0.2-0.1-0.0-0.1-0.40.40.1-0.10.1-0.10.2-0.4
Intermittent access terminal intake (last 3 days)0.10.20.6-0.20.20.10.1-0.10.3-0.3-0.50.5-0.5-0.10.80.5-0.1-0.00.5-0.50.50.50.1-0.1-0.50.4-0.4-0.5-0.50.2
Intermittent access total infusions0.30.30.9-0.60.8-0.11.00.60.50.4-0.30.3-0.90.70.90.90.60.8-0.10.0-0.10.2-0.50.5-0.1-0.20.2-0.40.0-0.6
Intermittent access day 1 locomotion0.30.30.9-0.40.3-0.30.20.3-0.1-0.10.4-0.4-0.30.40.10.40.30.8-0.90.8-0.7-0.7-0.70.70.7-0.40.40.40.7-0.8
Intermittent access day 15 total locomotion0.20.31.6-0.50.2-0.3-0.10.0-0.4-1.30.4-0.4-0.20.7-0.10.4-0.00.5-0.4-0.2-0.1-0.5-0.70.70.5-0.40.40.60.4-0.9
Intermittent access total locomotion0.70.82.1-1.01.1-0.20.80.90.20.10.2-0.2-0.91.20.31.21.01.4-0.80.5-0.7-0.6-1.31.30.6-1.01.00.30.8-1.3
Intermittent access standard deviation0.30.31.5-1.21.10.60.30.60.4-0.2-0.20.2-0.70.40.31.0-0.01.0-0.50.1-0.1-0.8-0.50.50.8-0.40.40.20.5-0.4
Left kidney weight0.41.02.4-0.10.6-0.90.10.8-0.30.61.2-1.2-0.10.9-1.00.61.11.0-1.61.2-1.3-1.4-1.11.21.4-0.90.91.01.6-1.2
Right kidney weight0.20.71.80.2-0.1-0.80.10.3-0.60.11.3-1.30.30.7-0.80.00.80.7-1.21.2-1.2-0.5-1.01.00.5-0.90.90.61.2-0.8
Cocaine induced anxiety0.10.11.6-0.2-0.30.2-0.8-0.3-0.4-1.30.2-0.2-0.1-0.0-0.0-0.1-0.4-0.00.1-0.40.3-0.1-0.20.20.1-0.20.20.30.1-0.2
Post-drug Anxiety0.10.11.5-0.5-0.00.6-0.6-0.4-0.1-1.2-0.20.2-0.5-0.20.20.1-0.50.30.3-0.20.20.3-0.20.2-0.3-0.10.1-0.3-0.1-0.0
Baseline Anxiety0.50.62.2-0.60.80.91.00.31.10.9-1.31.3-0.70.00.70.80.40.70.90.00.20.60.2-0.3-0.60.3-0.3-1.5-0.50.4
Tail length1.64.712.82.8-1.7-3.6-1.1-0.5-2.7-1.13.2-3.22.20.9-3.2-1.51.2-0.1-1.92.2-2.4-2.2-2.02.12.2-1.91.92.22.2-2.0
Length with tail0.93.48.70.6-0.0-1.9-0.40.7-1.4-0.42.1-2.10.71.6-2.20.11.61.4-2.12.3-2.4-1.9-2.52.51.9-2.22.21.62.5-3.0
Length without tail0.40.93.7-1.91.31.50.41.21.00.7-0.40.4-1.11.00.41.50.71.5-0.60.7-0.50.3-0.90.8-0.3-0.60.6-0.20.8-1.6
Times rat made contact with spout0.60.71.8-0.71.2-0.11.01.00.50.6-0.30.3-0.91.30.11.31.31.40.10.5-0.6-0.7-1.01.00.7-0.90.9-0.20.4-1.3
Lifetime Intake0.20.21.4-0.60.7-0.11.20.30.50.4-0.50.5-0.80.40.90.70.40.8-0.10.0-0.00.1-0.20.2-0.10.0-0.0-0.6-0.1-0.2
Liver weight, left0.20.41.40.2-0.30.10.2-0.50.3-0.2-0.10.10.4-0.60.2-0.1-0.4-0.50.5-0.50.60.90.9-0.9-0.91.2-1.2-0.8-0.70.9
Liver weight, right1.11.85.6-1.51.21.81.90.71.91.1-1.41.4-1.20.51.51.30.80.91.6-0.80.92.00.3-0.3-2.00.8-0.8-2.4-1.00.7
Locomotor activity0.81.23.20.6-0.6-1.41.00.5-0.90.51.8-1.81.00.9-1.1-0.81.10.5-1.51.6-1.7-0.7-1.01.10.7-1.21.21.01.2-0.6
Locomotor testing distance1.22.04.20.10.1-1.31.61.0-0.61.01.6-1.60.61.6-1.1-0.21.71.4-1.82.0-2.1-1.3-1.71.71.3-1.71.71.01.8-1.3
Locomotor testing rearing3.96.012.0-0.91.3-1.12.32.6-0.22.32.0-2.0-0.43.5-1.21.03.42.9-2.52.8-3.0-1.5-3.43.51.5-3.53.51.62.9-3.2
Locomotion in novel chamber0.60.72.31.5-1.3-0.5-0.9-0.7-0.90.60.4-0.41.1-0.9-1.2-1.5-0.5-0.8-0.70.9-0.7-1.10.3-0.31.1-0.30.30.70.40.7
Locomotion in novel chamber post-restriction1.21.43.4-0.6-0.01.51.4-0.41.20.2-1.51.5-0.6-0.41.40.2-0.4-0.11.8-1.21.31.21.5-1.5-1.21.4-1.4-1.9-1.81.2
Fecal boli incidents, locomotor time 10.60.72.0-0.40.20.7-0.6-1.10.2-1.3-1.31.3-0.4-1.20.80.2-1.4-0.30.6-1.01.00.00.9-0.9-0.00.9-0.9-0.8-0.90.6
Change in fecal boli incidents, locomotor task0.20.21.6-0.50.30.80.70.60.61.3-0.30.3-0.10.40.30.10.40.00.2-0.10.10.50.2-0.2-0.50.4-0.4-0.1-0.10.4
Time >=10cm from walls, locomotor time 10.30.31.1-0.50.70.60.6-0.20.70.1-0.90.9-0.4-0.50.70.6-0.20.50.3-0.10.30.10.4-0.4-0.10.3-0.3-1.1-0.30.7
Bouts of movement, locomotor time 10.70.83.4-0.90.8-0.10.61.20.3-0.20.5-0.5-0.61.70.10.91.41.2-0.40.4-0.6-0.7-1.21.20.7-0.70.70.60.7-1.9
Total resting periods, locomotor time 10.30.31.8-0.70.5-0.00.20.80.1-0.50.4-0.4-0.31.10.10.70.80.7-0.20.1-0.3-0.5-0.80.80.5-0.40.40.40.4-1.3
Rest time, locomotor task time 10.20.31.1-1.01.00.7-0.10.60.50.0-0.60.6-0.60.40.20.90.10.6-0.3-0.00.0-0.1-0.50.50.1-0.40.40.00.4-0.8
Distance moved, locomotor task time 10.30.41.4-0.20.40.21.10.90.51.2-0.40.4-0.40.90.20.21.10.70.00.4-0.40.3-0.70.7-0.3-0.70.7-0.20.2-0.1
Vertical activity count, locomotor time 10.50.62.0-0.30.4-0.11.10.90.31.00.3-0.3-0.31.2-0.20.31.40.90.00.9-0.90.5-1.01.0-0.5-1.01.0-0.20.4-0.7
Time >=10cm from walls, locomotor time 20.70.74.5-0.90.90.90.91.51.02.1-0.10.1-0.61.00.20.91.20.8-0.30.5-0.50.7-0.60.6-0.7-0.60.60.00.7-0.2
Bouts of movement, locomotor time 21.51.75.6-1.81.91.12.01.71.51.60.0-0.0-1.71.71.12.01.72.40.20.8-0.7-0.5-1.01.00.5-0.40.4-0.90.3-0.8
Total resting periods, locomotor time 21.51.65.4-2.02.01.41.91.61.61.2-0.20.2-1.81.51.42.11.42.30.40.6-0.5-0.4-0.80.80.5-0.20.2-1.00.1-0.7
Rest time, locomotor task time 21.41.64.50.0-0.30.9-1.4-1.40.2-1.8-1.31.30.1-1.90.7-0.4-2.1-1.41.2-1.51.60.51.6-1.6-0.51.7-1.7-0.7-1.71.3
Distance moved, locomotor task time 21.92.28.8-1.01.30.52.12.31.33.00.3-0.3-1.32.30.41.52.71.7-0.10.9-0.91.0-1.71.8-1.0-1.71.7-0.31.1-0.8
Vertical activity count, locomotor time 21.92.17.0-0.61.1-0.22.11.90.71.90.4-0.4-1.02.3-0.21.22.71.8-0.11.0-1.10.7-1.91.9-0.7-2.12.1-0.31.2-1.3
Light reinforcement 11.12.17.0-2.11.91.62.61.62.21.4-1.41.4-1.91.01.91.61.21.51.0-0.40.51.7-0.10.1-1.70.2-0.2-1.8-0.50.1
Light reinforcement 20.10.20.90.6-0.7-0.4-0.3-0.3-0.30.30.4-0.40.7-0.7-0.4-0.9-0.4-0.4-0.40.5-0.4-0.10.3-0.40.10.0-0.00.2-0.00.6
Bone: marrow area10.222.153.47.3-6.7-6.6-5.9-5.8-6.7-5.75.6-5.66.9-4.6-5.9-6.2-3.6-3.9-3.73.1-2.8-3.70.9-0.93.70.3-0.33.41.91.2
Bone: maximum diameter2.95.311.63.4-3.3-3.0-2.2-3.4-3.1-3.02.4-2.43.3-2.9-2.4-3.3-2.3-1.7-1.81.6-1.2-1.81.2-1.21.80.8-0.80.80.61.3
Bone: maximum force0.91.63.71.5-1.8-1.6-0.2-1.5-1.6-1.51.9-1.91.8-1.0-1.5-1.6-0.6-0.0-1.41.6-1.4-1.00.2-0.21.00.2-0.20.21.00.3
Bone: maximum moment0.91.64.11.6-1.8-1.6-0.2-1.5-1.7-1.52.0-2.01.8-0.9-1.5-1.6-0.6-0.1-1.41.5-1.3-1.00.3-0.31.00.3-0.30.40.90.3
Mean time between licks in bursts0.91.23.10.7-0.3-1.0-1.20.1-1.00.41.5-1.50.8-0.1-1.6-0.40.20.1-1.81.6-1.5-1.1-0.91.01.1-1.01.01.41.7-0.8
Mean num. licks in bursts1.01.23.4-1.61.61.21.81.01.40.7-1.51.5-1.61.11.41.50.91.40.9-0.60.50.3-0.20.3-0.30.1-0.1-1.2-0.6-0.4
Cd content in liver1.31.42.8-0.3-0.71.3-0.4-0.90.4-0.7-0.70.70.0-1.10.8-0.4-1.5-1.21.3-1.61.61.51.7-1.7-1.51.7-1.7-0.8-1.51.6
Co content in liver0.70.84.11.2-1.1-0.8-2.0-0.6-1.2-1.10.8-0.81.1-0.4-1.1-0.9-0.7-1.4-0.6-0.30.2-0.5-0.0-0.00.4-0.30.31.70.3-0.1
Cu content in liver0.50.61.60.4-0.60.1-0.7-1.0-0.2-1.1-0.60.60.4-1.10.0-0.6-1.2-0.90.5-0.80.80.51.0-1.0-0.51.2-1.2-0.4-0.70.8
Fe content in liver0.40.51.5-0.3-0.10.70.1-0.10.5-0.0-0.60.6-0.2-0.30.70.1-0.5-0.60.6-1.21.10.51.2-1.2-0.51.2-1.2-0.2-0.70.8
K content in liver1.61.65.40.6-0.80.10.1-1.70.2-0.8-0.70.70.1-1.50.9-0.5-1.2-0.81.4-1.11.20.91.9-1.9-0.92.3-2.3-1.8-1.51.6
Mg content in liver3.43.58.50.3-0.80.80.3-1.70.8-0.7-1.41.4-0.3-1.81.6-0.3-1.5-1.52.4-2.22.32.32.6-2.6-2.32.9-2.9-2.4-2.62.3
Mn content in liver4.34.911.3-0.6-0.11.60.5-1.51.4-0.8-2.22.2-0.7-2.02.5-0.0-1.9-1.22.5-2.52.72.92.9-2.9-2.93.4-3.4-2.9-2.72.7
Na content in liver1.01.12.9-0.60.11.10.3-0.60.9-0.3-1.31.3-0.6-1.11.20.2-0.9-0.21.1-0.81.00.81.4-1.4-0.91.7-1.7-1.5-1.31.2
Rb content in liver0.20.31.2-0.30.00.9-0.20.10.60.6-0.40.4-0.3-0.30.50.1-0.2-0.30.8-0.50.61.10.5-0.5-1.10.7-0.7-0.5-0.60.5
Se content in liver0.30.31.0-0.40.00.70.5-0.20.60.5-0.30.3-0.2-0.60.8-0.0-0.40.20.2-0.10.30.60.7-0.7-0.61.0-1.0-1.0-0.31.0
Sr content in liver0.10.10.70.00.2-0.4-0.3-0.0-0.3-0.20.1-0.10.20.1-0.50.2-0.10.2-0.50.2-0.3-0.8-0.20.20.8-0.30.30.60.3-0.3
Zn content in liver2.32.56.31.0-1.1-0.2-0.9-1.9-0.1-1.4-0.80.80.6-2.30.6-0.9-2.1-2.01.3-1.71.81.02.5-2.5-1.02.4-2.4-1.0-1.92.2
Bone: minimum diameter6.512.226.55.1-4.6-5.1-3.0-4.0-5.1-4.04.5-4.54.9-2.8-4.5-4.6-2.1-1.7-3.73.4-3.1-3.40.0-0.03.4-0.40.42.42.30.4
Time in familiar zone, hab. session 10.50.51.80.5-1.1-0.0-0.7-0.9-0.7-1.30.6-0.60.8-0.9-0.3-1.0-1.1-0.9-0.1-0.20.2-0.00.9-0.9-0.00.7-0.70.4-0.40.7
Time in novel zone, hab. session 10.70.71.5-0.81.20.31.10.80.91.1-0.90.9-1.10.90.61.21.01.00.5-0.20.10.3-0.90.9-0.3-0.70.7-0.80.0-0.5
Total zone transitions, hab. session 10.40.61.6-1.01.20.41.31.10.80.9-0.70.7-0.81.20.51.01.11.30.20.1-0.2-0.1-0.60.60.2-0.40.4-0.30.3-0.5
Total locomotion distance, hab. session 11.01.54.2-1.61.80.92.11.71.41.5-0.90.9-1.51.70.91.71.71.90.20.2-0.20.5-0.90.9-0.4-0.70.7-0.80.5-1.0
Locomotion velocity, hab. session 10.71.12.8-1.11.40.51.51.61.11.5-0.50.5-1.11.50.51.31.71.5-0.10.4-0.40.3-0.90.9-0.3-0.70.7-0.40.7-1.0
Time in familiar zone, hab. session 21.71.85.21.5-1.2-1.8-1.1-0.5-1.8-0.62.3-2.31.5-0.1-1.8-1.2-0.0-0.4-1.71.3-1.3-1.3-0.70.71.3-1.11.11.71.5-0.3
Time in novel zone, hab. session 23.83.88.6-1.51.02.21.2-0.22.10.1-2.92.9-1.6-0.72.51.0-0.7-0.22.8-2.22.32.41.8-1.7-2.42.1-2.1-2.7-2.61.5
Total zone transitions, hab. session 20.20.20.6-0.50.80.30.70.70.60.7-0.70.7-0.50.30.50.40.50.40.2-0.20.10.10.1-0.1-0.10.1-0.1-0.2-0.10.4
Total locomotion distance, hab. session 21.21.64.3-1.91.81.42.11.81.91.8-1.21.2-1.61.31.51.61.41.40.4-0.20.21.0-0.20.1-1.0-0.10.1-0.9-0.0-0.1
Locomotion velocity, hab. session 21.21.64.0-1.91.81.42.01.81.91.8-1.21.2-1.51.31.51.61.41.40.5-0.20.21.1-0.20.2-1.1-0.10.1-0.9-0.0-0.2
Novel to familiar place preference ratio2.12.26.61.7-1.2-2.0-0.9-0.7-2.0-0.81.5-1.51.70.2-2.1-1.40.0-0.1-1.51.5-1.6-2.6-1.11.12.6-1.31.31.91.2-0.9
Novelty place preference1.71.85.81.5-1.1-1.8-1.0-0.7-1.8-0.71.2-1.21.60.1-1.9-1.2-0.1-0.2-1.31.2-1.4-2.4-0.90.92.4-1.11.11.80.9-0.7
Time in novel zone, NPP test1.41.54.91.4-1.0-1.7-0.8-0.6-1.7-0.71.1-1.11.40.1-1.8-1.2-0.1-0.2-1.11.1-1.2-2.2-0.90.92.2-1.11.11.60.8-0.7
Total zone transitions, NPP test1.42.05.5-1.81.91.62.31.22.01.2-2.22.2-1.70.81.81.50.81.31.3-1.00.90.90.5-0.5-0.80.7-0.7-1.6-0.90.6
Total locomotion distance, NPP test2.43.310.1-2.62.32.13.21.82.61.6-2.22.2-2.31.62.32.11.51.81.6-1.11.01.90.1-0.1-1.90.4-0.4-2.1-0.80.2
Locomotion velocity, NPP test2.43.410.9-2.82.52.23.32.12.61.9-2.12.1-2.41.92.22.31.72.31.2-0.70.61.5-0.30.3-1.50.0-0.0-1.9-0.4-0.1
Intraocular pressure2.73.87.51.2-0.4-2.5-0.80.3-1.9-0.22.6-2.61.60.6-2.3-0.90.80.7-2.72.5-2.5-2.7-2.02.02.7-2.12.12.32.7-1.3
Delta distance traveled before/after self-admin0.40.51.3-0.50.30.60.80.60.90.9-0.70.7-0.50.21.00.20.3-0.20.9-0.70.71.10.6-0.6-1.10.6-0.6-0.5-0.80.5
Delta ambulatory time before/after self-admin0.70.72.3-0.2-0.30.50.3-0.30.5-0.4-0.60.6-0.1-0.50.9-0.3-0.5-0.91.3-1.21.21.51.1-1.0-1.50.9-0.9-0.7-1.20.7
Parametrial fat weight0.71.43.71.2-1.6-0.1-1.2-1.5-0.5-1.1-0.30.31.2-1.6-0.2-1.6-1.5-1.90.7-0.80.91.11.5-1.5-1.11.4-1.4-0.4-1.01.2
Pavlov. Cond. lever latency0.91.12.9-0.0-0.50.9-0.4-1.10.4-1.0-0.80.8-0.1-1.40.8-0.3-1.5-0.91.2-1.31.40.91.4-1.3-0.91.3-1.3-1.0-1.51.7
Pavlov. Cond. magazine entry latency0.30.41.10.3-0.4-0.70.20.5-0.40.71.0-1.00.30.7-0.5-0.40.90.1-0.70.8-0.80.1-0.70.6-0.1-0.70.70.50.8-0.8
Pavlov. Cond. change in total contacts1.01.12.20.7-0.4-1.3-0.10.6-0.90.61.4-1.40.71.1-1.3-0.51.20.3-1.21.1-1.3-0.9-1.21.20.9-1.11.11.41.5-1.3
Pavlov. Cond. index score0.50.71.50.4-0.2-0.90.10.6-0.60.71.1-1.10.40.9-0.8-0.31.00.4-1.01.1-1.2-0.4-1.01.00.4-0.90.90.81.2-1.2
Pavlov. Cond. latency score0.60.81.80.3-0.0-0.90.20.7-0.50.81.0-1.00.31.0-0.8-0.11.20.6-1.01.2-1.2-0.5-1.11.10.5-1.01.00.81.3-1.3
Pavlov. Cond. lever contacts0.70.92.10.10.3-0.80.20.9-0.40.90.8-0.80.21.1-0.80.11.20.7-1.11.2-1.2-0.7-1.21.20.8-1.11.11.01.4-1.4
Pavlov. Cond. magazine entry number0.20.20.8-0.30.60.40.1-0.20.5-0.3-0.90.9-0.4-0.40.40.6-0.40.20.6-0.60.6-0.30.4-0.40.30.4-0.4-0.6-0.70.4
Pavlov. Cond. intertrial magazine entries3.64.310.12.0-1.5-2.9-1.3-0.9-2.7-1.12.5-2.52.4-0.1-3.1-1.7-0.10.1-2.82.2-2.3-3.2-1.31.33.2-1.61.62.72.4-1.0
Pavlov. Cond. lever-magazine prob. diff.0.40.51.10.3-0.1-0.80.20.5-0.40.70.8-0.80.30.8-0.6-0.20.90.4-0.80.9-0.9-0.3-0.90.80.4-0.80.80.61.1-1.0
Pavlov. Cond. response bias0.30.41.00.6-0.6-0.8-0.10.3-0.70.51.0-1.00.60.6-0.8-0.60.6-0.2-0.70.7-0.80.0-0.60.5-0.0-0.60.60.80.9-0.7
Pavlov. Cond. lever latency0.30.31.3-0.50.40.6-0.31.00.41.10.1-0.1-0.20.6-0.00.40.60.1-0.30.5-0.40.6-0.70.7-0.6-0.90.90.50.4-0.8
Pavlov. Cond. magazine entry latency0.30.41.40.5-0.5-0.4-1.0-0.1-0.6-0.10.8-0.80.7-0.4-0.5-0.8-0.4-0.6-0.80.4-0.4-0.90.2-0.20.90.3-0.31.20.50.1
Pavlov. Cond. change in total contacts0.40.61.41.1-0.9-1.2-0.5-0.8-0.9-0.50.8-0.81.0-0.7-0.8-1.1-0.5-0.6-0.70.4-0.4-0.90.4-0.40.90.5-0.50.60.40.5
Pavlov. Cond. index score0.70.92.01.3-1.3-1.3-1.0-1.0-1.3-1.01.1-1.11.3-0.9-1.0-1.4-0.8-0.9-0.90.4-0.4-1.10.4-0.41.10.5-0.51.00.50.6
Pavlov. Cond. latency score0.81.02.01.3-1.2-1.4-1.0-0.9-1.3-0.91.2-1.21.3-0.8-1.0-1.4-0.7-0.8-1.00.5-0.5-1.30.3-0.31.30.4-0.41.10.60.5
Pavlov. Cond. lever contacts0.20.30.80.2-0.2-0.30.7-0.70.0-0.8-0.30.3-0.1-0.40.4-0.1-0.3-0.10.6-0.60.60.00.7-0.7-0.00.9-0.9-0.8-0.60.8
Pavlov. Cond. magazine entry number0.40.52.2-0.40.40.50.8-0.20.7-0.1-0.90.9-0.70.20.70.70.20.41.2-0.70.71.00.1-0.2-1.10.0-0.0-1.5-0.90.1
Pavlov. Cond. intertrial magazine entries1.11.55.00.5-0.70.30.6-1.60.3-1.0-1.51.50.1-1.31.0-0.7-1.1-0.61.8-1.01.21.41.3-1.3-1.41.1-1.1-2.2-1.81.5
Pavlov. Cond. lever-magazine prob. diff.0.70.91.81.2-1.2-1.3-1.0-1.0-1.3-0.91.2-1.21.3-0.9-0.9-1.3-0.8-0.8-0.90.4-0.4-1.20.5-0.41.20.5-0.51.00.40.6
Pavlov. Cond. response bias0.20.31.10.5-0.5-0.40.1-0.9-0.3-1.1-0.10.10.3-0.60.0-0.5-0.6-0.40.4-0.50.5-0.20.7-0.70.20.9-0.9-0.4-0.40.8
Time in closed arm before self-admin0.70.81.90.8-0.1-1.40.30.8-0.51.31.1-1.10.50.8-0.9-0.31.3-0.1-1.11.1-1.20.2-0.90.9-0.2-0.90.91.01.1-1.0
Time in closed arm after self-admin0.50.51.40.8-0.5-1.1-0.50.3-0.8-0.11.0-1.00.90.4-1.1-0.70.4-0.6-0.70.4-0.60.2-0.50.5-0.2-0.50.51.20.7-0.9
Time in open arm before self-admin0.40.50.9-0.90.70.7-0.30.80.20.60.6-0.6-0.20.5-0.20.50.30.9-0.50.9-0.8-0.8-0.90.90.9-0.80.80.50.7-0.5
Time in open arm after self-admin0.20.21.9-0.20.10.3-0.3-0.1-0.00.30.1-0.10.1-0.4-0.1-0.0-0.30.6-0.40.7-0.5-1.4-0.20.21.4-0.10.10.10.40.5
Bone: periosteal estimation5.611.525.65.1-4.7-5.0-3.1-4.0-4.9-4.04.4-4.44.9-2.9-4.4-4.4-2.1-1.9-3.22.9-2.6-3.10.4-0.43.1-0.00.02.21.90.5
Bone: periosteal perimeter4.67.715.43.6-3.3-3.9-2.6-2.8-3.9-3.03.6-3.63.7-2.1-3.5-3.4-1.6-1.0-3.22.9-2.6-3.3-0.20.23.3-0.60.62.32.0-0.1
Bone: post-yield work1.01.43.61.5-1.5-1.3-0.8-1.9-1.6-1.71.0-1.01.7-1.5-1.2-1.7-1.2-0.2-1.11.4-1.1-1.20.4-0.41.20.5-0.5-0.10.70.6
Progressive ratio test 1 active lever presses1.81.95.2-1.21.70.12.31.91.22.2-0.40.4-1.72.01.01.92.32.0-0.30.8-0.80.4-1.41.5-0.4-1.01.0-0.60.6-1.5
Progressive ratio test 1 breakpoint1.91.95.7-1.11.6-0.22.31.91.02.1-0.10.1-1.62.10.71.82.42.0-0.61.0-1.10.2-1.61.6-0.1-1.11.1-0.50.9-1.7
Progressive ratio test 1 inactive lever presses1.21.35.4-1.21.40.72.30.91.61.6-1.51.5-1.50.91.41.51.11.40.8-0.30.30.40.2-0.2-0.30.6-0.6-1.5-0.60.1
Progressive ratio test 2 active lever presses0.40.51.30.20.1-0.90.20.5-0.40.40.7-0.7-0.10.9-0.50.30.90.5-0.90.8-0.9-0.4-1.11.10.5-0.70.70.70.9-0.9
Progressive ratio test 2 breakpoint0.50.61.80.10.3-0.80.30.7-0.30.50.7-0.7-0.31.2-0.50.61.10.7-0.80.7-0.9-0.4-1.31.30.4-0.80.80.70.9-1.1
Progressive ratio test 2 inactive lever presses0.10.11.00.3-0.3-0.6-0.1-0.5-0.5-1.00.3-0.30.3-0.2-0.3-0.0-0.3-0.1-0.2-0.10.0-0.40.1-0.20.40.2-0.20.10.0-0.2
Incentive Sensitization - Responses0.30.31.00.6-0.4-0.7-0.6-0.4-0.8-0.70.7-0.70.40.1-0.8-0.2-0.10.0-0.50.4-0.4-1.0-0.50.51.0-0.30.30.60.4-0.2
Incentive Sensitization - Breakpoint0.30.31.00.6-0.3-0.7-0.7-0.4-0.8-0.70.6-0.60.40.1-0.9-0.1-0.1-0.0-0.40.3-0.4-1.0-0.50.51.0-0.30.30.60.5-0.1
Sum of active levers in priming session hrs 5-60.40.41.50.40.1-0.6-0.10.5-0.40.51.2-1.20.20.4-0.80.10.50.1-1.00.8-0.8-0.5-0.50.50.5-0.80.80.90.8-0.4
Progressive ratio1.31.53.61.9-1.8-0.9-1.8-1.6-1.4-1.11.1-1.11.8-1.8-1.4-1.8-1.5-1.5-0.50.8-0.5-0.80.6-0.60.70.2-0.20.70.11.2
Food seeking constrained by brief footshock0.60.72.51.2-1.6-0.9-1.2-0.8-1.0-0.60.6-0.61.6-0.6-1.0-1.5-0.6-1.30.0-0.10.0-0.40.7-0.70.40.3-0.30.9-0.0-0.1
Seeking ratio, punishment vs. effort0.30.41.7-0.90.70.21.00.90.60.5-0.60.6-0.61.30.50.71.00.70.4-0.60.30.3-0.30.3-0.3-0.20.2-0.1-0.0-1.1
Retroperitoneal fat weight1.75.712.8-0.10.8-1.30.92.5-0.62.12.2-2.20.03.1-2.20.93.32.1-2.62.9-3.1-1.5-3.33.31.5-3.33.32.13.2-3.6
Reaction time number correct0.50.71.90.6-1.20.0-0.2-1.2-0.4-0.6-0.00.00.9-1.40.2-1.4-1.2-0.90.2-0.10.20.81.3-1.2-0.81.3-1.3-0.5-0.71.0
Reaction time mean minus median0.50.62.60.7-1.10.1-0.9-0.6-0.1-0.3-0.30.30.7-0.90.0-0.9-0.7-1.50.6-0.40.51.60.9-0.9-1.60.6-0.6-0.3-0.70.5
Reaction time mean minus median AUC1.62.04.60.9-1.50.3-0.4-1.50.1-0.7-1.01.00.7-1.80.6-1.3-1.5-1.91.4-1.01.22.12.0-2.0-2.11.8-1.8-1.4-1.71.7
Reaction time num false alarms1.11.53.01.6-1.5-1.7-0.6-1.3-1.7-1.11.5-1.51.7-1.0-1.3-1.7-0.9-0.5-1.41.1-1.1-1.7-0.10.11.7-0.50.51.00.60.4
Reaction time num false alarms AUC1.11.53.91.8-1.9-1.5-0.8-2.0-1.6-1.51.1-1.11.7-1.7-0.9-1.9-1.5-1.1-0.70.4-0.3-1.10.7-0.71.10.3-0.30.4-0.21.3
Reaction time trials correct on left0.50.71.90.6-1.20.0-0.2-1.2-0.4-0.6-0.00.00.9-1.40.2-1.4-1.2-0.90.2-0.10.20.81.3-1.2-0.81.3-1.3-0.5-0.71.0
Reaction time trials on left0.60.92.10.6-1.30.1-0.2-1.3-0.4-0.6-0.10.10.9-1.50.3-1.4-1.3-1.00.3-0.10.30.91.4-1.3-0.91.4-1.4-0.6-0.81.1
Reaction time mean0.30.42.30.1-0.40.3-0.50.00.20.5-0.50.50.2-0.10.3-0.3-0.1-1.21.0-0.80.71.50.5-0.6-1.50.3-0.3-0.2-0.7-0.1
Reaction time mean AUC0.30.42.20.0-0.20.3-0.30.20.40.6-0.50.5-0.10.00.40.10.1-0.91.0-0.80.81.50.5-0.5-1.50.4-0.4-0.3-0.7-0.1
Median of all reaction times0.30.41.8-0.1-0.10.3-0.50.20.40.6-0.50.5-0.00.10.40.0-0.0-1.01.0-0.90.81.30.4-0.4-1.30.2-0.2-0.1-0.6-0.2
Reaction time omissions2.33.27.40.2-0.81.30.2-1.40.9-0.4-1.61.6-0.1-1.91.5-0.5-1.5-1.52.4-1.82.02.72.3-2.3-2.72.2-2.2-2.4-2.42.2
Reaction time false alarm rate0.60.82.31.2-0.9-1.4-0.6-0.9-1.3-0.81.2-1.21.1-0.6-1.0-1.0-0.5-0.4-0.90.7-0.7-1.5-0.30.31.5-0.70.70.90.40.3
Reaction time premature initiation rate1.01.44.3-1.21.40.41.01.20.40.5-0.00.0-1.01.60.01.41.32.1-0.80.8-0.9-1.6-1.71.71.6-1.51.50.31.0-1.0
Reaction time premature initiations0.20.21.4-0.70.50.50.90.20.30.0-0.40.4-0.50.40.40.50.21.2-0.20.4-0.3-0.7-0.40.50.7-0.20.2-0.40.20.1
Std. dev. reaction times0.91.34.30.4-1.00.7-0.5-0.80.3-0.2-1.01.00.3-1.10.7-0.7-1.0-1.61.4-1.21.32.11.5-1.4-2.11.3-1.3-1.0-1.41.0
Reaction time trials completed0.60.92.10.6-1.30.1-0.2-1.3-0.4-0.6-0.10.10.9-1.50.3-1.4-1.3-1.00.3-0.10.30.91.4-1.3-0.91.4-1.4-0.6-0.81.1
Reaction time trials AUC0.50.71.70.6-1.20.1-0.1-1.1-0.3-0.5-0.10.10.8-1.30.3-1.3-1.2-0.90.3-0.00.20.91.3-1.2-0.91.3-1.3-0.6-0.71.0
Run reversals in cocaine runway, females1.51.53.6-0.70.80.5-0.21.80.11.20.5-0.5-0.31.8-1.00.91.61.2-0.71.2-1.3-0.7-1.91.90.7-1.71.71.31.6-1.4
Run reversals in cocaine runway, males1.41.42.91.3-1.1-1.5-1.6-0.5-1.6-1.31.7-1.71.3-0.0-1.7-0.9-0.1-0.6-1.20.8-0.9-1.4-0.80.81.4-0.70.71.70.9-1.0
Latency to leave start box in cocaine runway2.73.010.5-1.52.20.62.32.71.63.2-0.20.2-1.72.50.72.12.82.2-0.11.2-1.10.7-2.02.0-0.6-1.81.8-0.40.8-1.4
Latency to leave start box in cocaine runway, F5.96.515.3-2.43.20.62.63.41.43.10.3-0.3-2.13.60.03.03.63.9-1.22.3-2.3-1.2-3.53.51.2-3.33.30.22.2-2.8
Latency to leave start box in cocaine runway, M1.21.16.50.2-0.10.30.60.71.02.0-0.50.5-0.40.10.90.10.6-1.11.2-0.90.92.50.9-0.9-2.51.0-1.0-0.6-1.00.8
Std. dev. time between licks in bursts0.60.72.0-1.41.31.30.81.11.31.2-0.80.8-1.20.70.91.40.60.80.7-0.40.40.80.0-0.0-0.80.3-0.3-0.6-0.2-0.2
Total sessions with >9 infusions0.90.93.8-1.51.60.61.91.01.21.2-0.80.8-1.50.81.21.40.81.7-0.10.2-0.10.1-0.50.6-0.1-0.30.3-0.90.2-0.1
Short access day 1 total inactive lever presses0.40.51.6-1.21.20.60.80.40.70.0-1.01.0-1.10.40.41.20.21.3-0.20.2-0.2-0.3-0.40.30.4-0.10.1-0.60.3-0.6
Short access day 10 total inactive lever presses0.20.20.60.4-0.6-0.3-0.1-0.6-0.5-0.80.3-0.30.5-0.3-0.6-0.6-0.30.10.00.2-0.2-0.70.1-0.10.7-0.20.2-0.10.10.4
Short access day 1 total infusions0.60.63.6-1.01.10.41.90.81.01.2-0.70.7-0.90.50.70.90.81.4-0.30.5-0.40.1-0.30.2-0.1-0.40.4-0.90.30.1
Short access day 10 total infusions1.11.27.1-1.31.50.72.70.81.31.3-1.01.0-1.60.91.61.41.11.90.20.3-0.2-0.2-0.10.10.20.3-0.3-1.5-0.3-0.2
Short access total infusions0.30.42.7-0.70.80.11.60.40.70.8-0.70.7-0.80.41.10.60.50.9-0.00.0-0.00.20.1-0.1-0.10.3-0.3-0.8-0.10.0
Short access day 1 locomotion1.31.46.1-1.51.60.62.51.41.31.5-0.60.6-1.61.71.01.91.72.0-0.00.3-0.30.0-0.70.7-0.0-0.30.3-1.00.3-0.7
Short access day 10 total locomotion0.70.72.90.2-0.2-1.0-0.10.2-0.8-0.01.1-1.10.40.4-0.6-0.10.30.5-1.71.3-1.3-1.1-0.80.91.2-0.60.61.11.1-1.2
Short access total locomotion1.11.24.4-1.51.50.62.11.31.11.4-0.40.4-1.51.30.91.71.31.9-0.40.5-0.50.1-0.80.9-0.0-0.40.4-0.80.5-0.6
One hour access (0.3 mA shock)0.20.20.90.2-0.1-0.40.2-0.6-0.1-0.9-0.70.7-0.3-0.30.60.1-0.4-0.20.5-0.80.70.20.2-0.2-0.20.3-0.3-0.5-0.50.1
Compulsive drug intake0.60.62.80.9-1.1-0.7-0.9-1.4-0.9-1.7-0.00.01.1-1.0-0.7-1.1-1.0-0.90.2-0.40.4-0.30.7-0.70.30.4-0.4-0.0-0.20.1
One hour access (shock baseline)0.20.20.60.1-0.10.0-0.0-0.30.2-0.2-0.40.4-0.4-0.50.80.1-0.4-0.40.4-0.50.50.70.2-0.2-0.70.4-0.4-0.5-0.60.7
Social response proportion0.91.03.31.0-1.6-0.2-0.4-1.8-0.9-1.21.0-1.01.4-1.4-0.4-1.4-1.3-0.80.30.20.10.41.1-1.1-0.41.1-1.1-0.7-0.51.1
Social responses0.70.93.7-1.00.51.21.7-0.31.00.3-0.70.7-0.7-0.21.40.5-0.20.71.1-0.60.80.71.0-0.9-0.71.3-1.3-1.9-0.91.0
Social time1.41.95.01.6-2.2-0.7-1.6-2.0-1.4-1.51.1-1.11.9-2.0-0.8-2.2-2.0-1.8-0.10.10.10.11.4-1.4-0.11.3-1.30.4-0.41.2
Soleus weight0.82.45.62.1-2.1-1.9-1.8-1.4-2.1-1.41.8-1.82.4-1.4-2.1-2.3-1.1-1.3-1.81.4-1.3-0.80.1-0.20.8-0.20.21.60.90.2
Bone: stiffness0.60.92.51.2-1.6-0.9-0.2-1.4-1.2-1.11.5-1.51.4-0.9-1.1-1.4-0.6-0.0-0.91.4-1.1-0.40.2-0.20.40.4-0.4-0.20.70.4
Tibialis anterior weight0.51.84.71.4-0.8-1.8-1.10.4-1.20.82.2-2.21.10.2-1.6-0.80.9-0.1-2.02.0-1.9-0.7-1.31.30.7-1.41.41.71.7-0.8
Time to tail flick, vehicle, before self-admin0.50.52.3-1.00.80.4-0.40.3-0.1-1.00.7-0.7-0.50.8-0.10.90.21.0-0.20.2-0.3-1.0-0.80.71.0-0.40.40.40.4-1.5
Time to tail flick, vehicle, after self-admin1.01.12.61.3-1.3-0.8-1.6-1.5-1.5-1.60.8-0.81.5-1.2-1.3-1.5-1.3-0.9-0.50.5-0.4-1.10.2-0.21.0-0.30.31.00.20.6
Time to tail flick, test, before self-admin3.03.07.12.2-2.1-2.2-2.7-1.5-2.5-2.12.5-2.52.4-0.7-2.4-1.8-0.9-1.5-1.00.7-0.9-1.4-0.50.51.3-0.90.92.20.7-1.1
Time to tail flick, test, after self-admin0.40.43.00.5-0.6-0.40.1-1.4-0.7-1.70.3-0.30.9-0.7-0.6-0.8-0.80.10.20.3-0.1-0.80.3-0.30.8-0.20.2-0.7-0.30.1
Delta time to tail flick, vehicle, before/after SA1.41.44.00.7-0.90.3-0.0-1.60.0-0.9-1.31.30.3-1.70.5-0.9-1.5-1.11.3-1.01.20.71.6-1.6-0.71.5-1.5-1.4-1.52.0
Delta time to tail flick, test, before/after SA0.50.51.20.0-0.10.50.5-1.00.1-0.9-1.01.00.2-0.90.3-0.6-1.0-0.00.5-0.40.5-0.20.9-0.90.20.7-0.7-1.0-0.61.1
Tibia length1.44.08.70.60.1-1.8-0.61.3-1.31.02.4-2.40.51.6-2.00.21.81.2-2.82.5-2.5-2.4-2.52.42.4-2.42.42.43.0-2.6
Ambulatory time before self-admin0.20.20.70.20.00.2-0.50.5-0.20.40.3-0.30.00.2-0.5-0.10.20.2-0.70.5-0.5-0.6-0.60.60.6-0.80.80.80.70.3
Ambulatory time after self-admin0.10.10.50.3-0.50.4-0.40.20.00.60.1-0.10.2-0.2-0.1-0.4-0.1-0.70.1-0.20.20.50.0-0.1-0.5-0.50.50.4-0.20.6
Bone: tissue strength2.82.76.6-2.52.02.61.90.92.21.1-2.42.4-2.20.52.51.80.21.21.6-1.51.51.10.7-0.7-1.11.0-1.0-1.9-1.20.6
Total heroin consumption0.40.41.70.5-0.3-0.1-0.2-1.00.2-0.6-0.40.4-0.4-1.10.30.3-0.7-0.50.6-0.30.50.80.7-0.8-0.90.7-0.7-1.3-0.70.8
Bone: trabecular number3.45.310.80.8-1.40.5-0.9-2.90.0-2.9-1.11.10.3-3.01.3-0.9-2.9-2.22.3-2.62.72.13.3-3.3-2.23.3-3.3-2.3-2.83.1
Bone: trabecular spacing2.33.06.9-0.81.3-0.10.92.50.22.00.4-0.4-0.62.6-0.80.82.51.7-1.41.7-1.9-1.1-2.62.61.1-2.62.61.62.0-2.4
Bone: trabecular thickness1.41.65.21.7-2.0-1.3-0.9-2.3-1.5-2.11.0-1.01.6-1.8-0.8-1.7-1.7-1.3-0.2-0.10.2-0.11.3-1.30.10.9-0.9-0.2-0.51.4
Bone: trabecular tissue density1.11.64.0-1.61.60.91.12.01.01.80.1-0.1-1.21.70.41.51.61.5-0.60.9-0.90.2-1.61.6-0.2-1.51.50.21.0-1.4
Water consumed over 24 hours2.73.37.4-2.32.22.32.61.52.72.0-2.32.3-2.30.92.42.21.11.31.9-1.01.11.80.6-0.6-1.80.8-0.8-2.4-1.30.4
Number of responses in last shaping day1.11.23.3-1.61.60.91.31.81.11.5-0.40.4-1.31.60.81.61.41.5-0.30.1-0.3-0.2-0.91.00.2-0.50.50.20.8-1.1