Hub : Genes

Zfp950

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R² and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

#	Tissue	Modality	RNA phenotype	h2	h2 SE	h2 P	xQTL R2	BLUP R2	ENET R2	LASSO R2	xQTL P	BLUP P	ENET P	LASSO P
1	NAcc	gene expression	Zfp950	0.07	0.04	1.4e-09	0.06	0.07	0.08	0.06	2.8e-07	4.6e-09	3.7e-09	2.2e-07
2	PL	gene expression	Zfp950	0.04	0.03	4.1e-04	0.03	0.03	0.02	0.03	7.5e-04	3.5e-04	2.3e-03	7.8e-04
3	Adipose	gene expression	Zfp950	0.03	0.02	3.1e-04	0.03	0.03	0.03	0.03	6.1e-04	8.5e-04	7.6e-04	8.3e-04
4	Brain	gene expression	Zfp950	0.06	0.05	9.5e-05	0.03	0.05	0.03	0.04	6.0e-04	3.2e-05	1.3e-03	1.3e-04

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4
Bone: apparent density	1.5	2.5	5.8	-2.4	1.1	-1.6	0.7
Area under the delay curve	1.2	1.2	2.4	-0.3	1.4	-0.7	1.6
BMI with tail	24.9	80.7	124.6	-11.2	8.3	-8.5	7.5
BMI without tail	17.2	35.6	50.9	-7.1	6.0	-5.4	5.2
Body weight	22.8	95.5	149.1	-12.2	9.1	-9.2	8.1
Weight adjusted by age	5.2	5.9	9.1	-3.0	2.4	-2.0	2.2
Bone surface	1.8	3.2	6.2	-2.5	1.3	-2.0	1.0
Bone volume	4.2	7.1	12.3	-3.5	2.1	-2.9	1.8
Breakpoint value in progressive ratio session	2.4	2.7	4.3	-1.4	2.1	-1.0	1.9
Number of licking bursts	0.2	0.2	0.5	0.3	0.3	0.7	-0.0
Context. condit. distance diff. score	0.1	0.1	0.2	0.2	-0.3	0.2	-0.5
Locomotion velocity, session 1	1.5	1.6	2.3	1.3	-1.1	1.5	-1.1
Locomotion distance, session 1	1.3	1.7	2.6	1.6	-1.5	0.8	-1.1
Locomotion velocity, session 2	0.9	1.0	1.7	1.0	-1.3	0.6	-1.0
Locomotion distance, session 2	0.5	0.7	1.7	-1.0	0.1	-1.3	0.4
Locomotion velocity, session 3	1.7	2.0	3.2	1.8	-1.5	1.0	-1.2
Locomotion distance, session 3	1.0	1.1	1.4	1.1	-1.2	0.7	-1.0
Stereotopy head waving bouts, day 3	0.1	0.1	0.2	0.5	-0.3	-0.1	-0.0
Stereotopy head waving duration, day 3	0.1	0.1	0.3	0.5	0.1	0.0	0.4
Locomotion velocity, session 7	0.1	0.1	0.2	0.4	-0.3	0.1	-0.3
Locomotion distance, session 7	0.3	0.3	0.6	-0.8	-0.2	-0.8	-0.2
Stereotopy head waving bouts, day 7	0.5	0.6	0.9	0.9	0.9	0.6	0.7
Stereotopy head waving duration, day 7	0.7	0.9	1.9	1.4	0.8	0.7	0.6
Locomotion velocity, session 8	2.3	2.8	3.6	1.5	-1.8	1.4	-1.9
Locomotion distance, session 8	0.8	1.2	2.1	0.6	-1.4	0.6	-1.4
Degree of sensitization distance	1.3	1.3	3.0	-1.7	0.9	-1.0	0.7
Degree of sensitization stereotypy	0.8	0.9	1.8	0.5	1.3	0.4	1.1
Conditioned locomotion	0.1	0.1	0.4	0.2	0.0	0.6	0.1
Cocaine response after cond. corrected	2.2	2.5	5.9	0.9	-2.4	0.0	-1.8
Cocaine response after cond. not corrected	3.7	4.1	7.4	1.5	-2.7	1.1	-2.3
Cocaine response before conditioning	1.3	1.6	4.7	1.0	-0.1	2.2	-0.7
Saline control response	0.1	0.1	0.2	0.3	0.1	0.2	0.4
Bone: connectivity density	0.1	0.2	0.3	-0.6	-0.2	-0.4	-0.4
Bone: cortical apparent density	5.5	7.2	9.7	3.0	-3.1	1.9	-2.6
Bone: cortical area	10.7	16.2	23.3	-4.8	3.9	-3.8	3.5
Bone: cortical porosity	0.8	0.9	1.5	-1.2	1.0	-0.9	0.7
Bone: cortical porosity	1.9	2.0	2.7	-1.6	1.6	-1.2	1.2
Bone: cortical thickness	7.4	12.1	17.6	-4.2	3.0	-3.6	2.9
Bone: cortical thickness	9.1	10.5	13.2	-3.4	2.8	-3.6	3.1
Bone: cortical tissue density	6.3	8.3	10.9	3.2	-3.3	2.1	-2.8
Condit. Reinf. active minus inactive responses	2.5	2.8	4.7	1.2	-1.9	1.1	-2.2
Condit. Reinf. active-inactive response ratio	2.5	2.7	3.5	1.5	-1.7	1.5	-1.9
Condit. Reinf. active responses	0.6	0.7	1.6	-0.4	-1.0	-0.4	-1.3
Condit. Reinf. inactive responses	1.3	1.6	3.4	-1.8	0.5	-1.6	0.2
Incentive salience index mean	1.5	1.9	3.7	0.7	-1.8	0.3	-1.9
Condit. Reinf. lever presses	0.7	0.9	1.7	0.2	-1.3	-0.7	-1.2
Condit. Reinf. active minus inactive responses	1.1	1.3	2.3	-1.4	1.5	-0.5	1.0
Condit. Reinf. active-inactive response ratio	2.4	2.5	4.2	-1.5	2.0	-0.9	1.6
Condit. Reinf. active responses	1.1	1.6	2.6	-1.5	1.6	-0.6	1.0
Condit. Reinf. inactive responses	0.2	0.3	0.6	-0.8	0.6	-0.0	0.2
Condit. Reinf. lever presses	1.1	1.5	2.8	-1.7	1.2	-0.8	0.9
Condit. Reinf. lever reinforcers received	0.4	0.6	1.1	-1.1	1.0	-0.1	0.5
Conditioned reinforcement - actives	5.0	5.0	5.7	2.4	-2.2	2.1	-2.2
Conditioned reinforcement - inactives	0.3	0.3	0.4	0.7	-0.6	0.3	-0.6
Conditioned locomotion	4.2	5.1	5.9	2.1	-2.4	2.1	-2.4
Patch foraging indifference point 0 sec	5.4	8.6	10.9	-3.3	2.9	-2.8	2.7
Patch foraging indifference point AUC	0.6	0.7	1.4	-0.4	1.0	-0.6	1.2
Delay disc. indifference point, 0s delay	1.2	1.3	1.8	-1.1	1.0	-1.3	1.1
Delay disc. indifference point, 16s delay	0.6	0.6	1.3	0.2	1.1	0.1	1.1
Delay disc. indifference point, 2s delay	0.3	0.4	0.7	0.0	0.5	-0.8	0.8
Delay disc. indifference point, 24s delay	1.0	0.9	1.6	-0.3	1.2	-0.7	1.3
Delay disc. indifference point, 4s delay	0.7	0.8	1.4	-0.2	1.1	-0.7	1.2
Delay disc. indifference point, 8s delay	0.4	0.4	0.9	0.1	0.7	-0.3	0.9
Indifference point function ln k	0.2	0.3	0.7	-0.9	-0.2	-0.6	-0.2
Indifference point function log k	0.2	0.3	0.7	-0.9	-0.2	-0.6	-0.2
Patch foraging total patch changes 0 sec	6.5	10.5	13.4	-3.7	3.2	-3.0	3.0
Patch foraging total patch changes 12 sec	3.9	5.0	5.7	-2.4	2.3	-2.0	2.2
Patch foraging total patch changes 18 sec	2.2	2.8	3.7	-1.9	1.7	-1.5	1.6
Patch foraging total patch changes 24 sec	0.7	0.8	1.1	-0.7	1.1	-0.6	1.1
Patch foraging total patch changes 6 sec	4.6	6.8	7.7	-2.8	2.7	-2.2	2.7
Patch foraging time to switch 0 sec	1.5	2.3	2.8	1.7	-1.5	1.5	-1.5
Patch foraging water rate 0 sec	3.3	5.3	6.8	-2.6	2.1	-2.3	2.2
Patch foraging water rate 12 sec	2.7	4.1	5.3	-2.3	2.2	-1.6	2.0
Patch foraging water rate 18 sec	1.7	2.2	3.2	-1.8	1.1	-1.6	1.4
Patch foraging water rate 24 sec	5.3	7.4	10.6	-3.3	2.1	-2.9	2.4
Patch foraging water rate 6 sec	2.1	3.1	5.3	-2.3	1.4	-1.8	1.5
Seeking ratio, delayed vs. immediate footshock	8.5	9.8	12.1	3.3	-3.5	2.3	-3.3
Distance traveled before self-admin	0.2	0.2	0.5	0.4	-0.2	-0.7	0.4
Distance traveled after self-admin	0.6	0.7	1.3	1.1	-1.0	0.3	-0.6
Extensor digitorum longus weight	1.5	5.8	10.1	-3.2	2.4	-1.8	2.0
Bone: elastic displacement	0.4	0.5	0.9	-0.5	0.7	-0.6	0.9
Bone: elastic work	4.5	5.7	8.1	-2.3	1.9	-2.8	2.4
Bone: endosteal estimation	1.7	3.7	5.4	-2.3	1.8	-1.9	1.6
Bone: endosteal perimeter	3.3	6.8	7.9	-2.7	2.8	-2.3	2.6
Epididymis fat weight	26.2	61.1	97.5	-9.9	7.7	-6.8	6.5
Delta time in closed arm before/after self-admin	0.4	0.4	0.9	0.1	-1.0	0.0	-0.8
Delta time in open arm before/after self-admin	0.6	0.5	1.8	0.1	0.6	1.3	-0.2
Diff in mean of infusions in LGA sessions	0.7	0.8	1.8	-0.2	1.4	-0.2	1.2
Delay discount exponential model param	1.3	1.4	2.8	0.3	-1.5	0.7	-1.7
Extinction: sum of active levers before priming	0.1	0.1	0.2	0.4	0.3	0.5	0.1
Active lever presses in extinction session 6	3.2	3.1	4.5	-1.3	2.0	-1.6	2.1
Bone: final force	8.6	13.8	19.9	-4.5	3.2	-3.9	3.1
Bone: final moment	8.8	14.3	21.1	-4.6	3.3	-3.9	3.2
Food consumed during 24 hour testing period	0.3	0.3	1.0	-1.0	0.3	-0.2	0.3
Glucose	5.8	8.7	14.9	-2.7	3.9	-1.6	3.2
Heart weight	8.2	11.7	15.5	-3.9	3.6	-2.7	3.3
Delay discount hyperbolic model param	1.2	1.3	2.4	0.2	-1.4	0.8	-1.6
Intermittent access intake day 1-15 change	0.1	0.1	0.3	-0.2	0.5	-0.0	0.5
Intermittent access intake escalation	0.1	0.1	0.1	-0.3	0.2	-0.2	0.3
Intermittent access intake escalation 2	0.2	0.2	0.4	-0.6	0.4	-0.2	0.4
Intermitt. access day 1 inactive lever presses	0.8	0.8	1.2	-0.9	1.1	-0.6	0.9
Intermitt. access day 15 inactive lever presses	2.6	2.9	3.8	-1.5	1.7	-1.6	1.9
Intermitt. access escalation Index	0.2	0.2	0.3	0.1	-0.4	0.3	-0.5
Intermittent access day 1 total infusions	0.4	0.4	0.8	0.9	-0.6	0.5	-0.5
Intermittent access day 15 total infusions	0.1	0.1	0.3	0.5	-0.3	0.3	-0.2
Intermittent access terminal intake (last 3 days)	0.0	0.0	0.1	0.3	-0.0	0.3	0.1
Intermittent access total infusions	0.7	0.7	1.2	1.1	-0.7	0.9	-0.6
Intermittent access day 1 locomotion	2.0	2.1	3.0	1.7	-1.7	1.1	-1.3
Intermittent access day 15 total locomotion	0.1	0.1	0.2	0.2	0.5	0.2	0.4
Intermittent access total locomotion	1.0	1.1	1.7	1.3	-1.2	0.7	-0.9
Intermittent access standard deviation	0.4	0.4	1.0	0.7	-0.1	1.0	-0.3
Left kidney weight	10.4	29.3	53.5	-7.3	4.0	-5.6	4.0
Right kidney weight	10.0	28.1	51.5	-7.2	3.8	-5.5	4.0
Cocaine induced anxiety	3.7	4.2	4.9	2.1	-2.2	1.9	-2.0
Post-drug Anxiety	1.1	1.3	1.7	1.3	-0.9	1.3	-1.0
Baseline Anxiety	1.2	1.3	2.5	-0.9	1.6	-0.7	1.2
Tail length	0.8	2.4	3.6	-1.7	1.9	-0.9	1.5
Length with tail	2.7	10.1	15.4	-3.9	3.1	-2.8	2.7
Length without tail	3.6	7.9	14.7	-3.8	2.3	-2.7	2.0
Times rat made contact with spout	1.0	1.1	2.2	-1.5	1.0	-0.9	0.8
Lifetime Intake	0.8	0.9	1.5	1.2	-0.9	0.8	-0.7
Liver weight, left	5.1	8.1	11.5	-3.4	2.8	-2.6	2.4
Liver weight, right	6.9	11.4	18.2	-4.3	3.3	-3.0	2.7
Locomotor activity	0.1	0.2	0.4	0.3	-0.4	0.6	-0.5
Locomotor testing distance	0.2	0.4	0.7	0.4	-0.9	0.2	-0.7
Locomotor testing rearing	0.1	0.2	0.5	-0.2	0.5	0.0	0.7
Locomotion in novel chamber	1.1	1.4	3.0	-1.3	0.4	-1.7	0.9
Locomotion in novel chamber post-restriction	0.5	0.7	2.1	-0.5	-0.1	-1.4	0.6
Fecal boli incidents, locomotor time 1	0.3	0.3	0.8	-0.0	0.9	0.5	0.5
Change in fecal boli incidents, locomotor task	0.3	0.3	0.9	-1.0	-0.0	-0.6	-0.1
Time >=10cm from walls, locomotor time 1	0.3	0.3	0.4	0.6	-0.5	0.6	-0.6
Bouts of movement, locomotor time 1	0.1	0.1	0.2	-0.3	0.4	0.1	0.1
Total resting periods, locomotor time 1	0.1	0.1	0.3	-0.5	0.4	-0.1	0.2
Rest time, locomotor task time 1	0.6	0.7	1.8	-1.3	-0.1	-0.9	0.1
Distance moved, locomotor task time 1	0.1	0.2	0.5	0.7	0.2	-0.1	0.3
Vertical activity count, locomotor time 1	0.3	0.3	1.0	1.0	-0.3	-0.0	-0.1
Time >=10cm from walls, locomotor time 2	0.2	0.2	0.4	-0.5	0.0	-0.7	0.1
Bouts of movement, locomotor time 2	0.1	0.1	0.2	0.3	-0.1	0.4	-0.1
Total resting periods, locomotor time 2	0.1	0.1	0.2	0.4	-0.1	0.4	-0.1
Rest time, locomotor task time 2	0.1	0.1	0.3	0.2	-0.2	0.6	-0.2
Distance moved, locomotor task time 2	0.2	0.2	0.8	-0.2	-0.1	-0.9	0.1
Vertical activity count, locomotor time 2	0.2	0.2	0.3	0.3	-0.6	-0.3	-0.4
Light reinforcement 1	0.3	0.5	1.3	-0.3	-0.6	-1.1	-0.2
Light reinforcement 2	0.3	0.4	0.5	0.7	-0.6	0.1	-0.7
Bone: marrow area	1.9	4.1	6.0	-2.5	1.9	-2.0	1.7
Bone: maximum diameter	4.6	8.4	11.2	-3.3	3.2	-2.3	2.6
Bone: maximum force	6.9	12.0	18.5	-4.3	2.8	-3.9	2.6
Bone: maximum moment	6.9	12.0	19.0	-4.4	2.8	-3.8	2.6
Mean time between licks in bursts	1.3	1.8	4.1	0.8	-0.9	2.0	-1.4
Mean num. licks in bursts	0.9	1.0	2.1	-1.3	0.2	-1.5	0.5
Cd content in liver	2.1	2.2	3.3	1.1	-1.8	1.1	-1.8
Co content in liver	0.3	0.4	1.0	-0.5	-0.4	-1.0	-0.2
Cu content in liver	0.3	0.3	0.5	-0.7	0.7	-0.3	0.6
Fe content in liver	0.1	0.1	0.1	0.3	-0.1	0.3	-0.2
K content in liver	0.4	0.4	0.7	-0.5	0.8	0.2	0.8
Mg content in liver	0.9	0.9	1.9	-0.5	1.2	-0.2	1.4
Mn content in liver	0.4	0.5	0.8	-0.8	0.3	-0.9	0.6
Na content in liver	3.1	3.3	5.5	-1.5	2.3	-0.7	2.2
Rb content in liver	0.2	0.3	0.7	0.9	-0.2	0.5	-0.0
Se content in liver	0.1	0.2	0.4	0.5	-0.1	0.6	-0.1
Sr content in liver	1.2	1.1	2.0	1.4	-1.3	0.6	-0.7
Zn content in liver	0.5	0.5	0.8	-0.8	0.3	-0.9	0.8
Bone: minimum diameter	5.3	10.0	13.5	-3.7	3.2	-2.9	2.8
Time in familiar zone, hab. session 1	2.7	2.5	3.3	-1.4	1.8	-1.4	1.7
Time in novel zone, hab. session 1	5.6	5.5	6.4	2.4	-2.1	2.5	-2.3
Total zone transitions, hab. session 1	0.2	0.2	0.5	-0.1	0.2	-0.7	0.6
Total locomotion distance, hab. session 1	0.3	0.4	0.6	0.7	-0.4	0.7	-0.5
Locomotion velocity, hab. session 1	0.1	0.2	0.3	0.4	-0.4	0.5	-0.5
Time in familiar zone, hab. session 2	0.8	0.9	1.3	0.9	-0.5	1.1	-1.1
Time in novel zone, hab. session 2	0.3	0.3	0.5	-0.6	0.4	-0.6	0.7
Total zone transitions, hab. session 2	0.3	0.3	0.6	-0.4	0.4	-0.7	0.7
Total locomotion distance, hab. session 2	0.2	0.3	0.5	-0.7	0.6	-0.4	0.4
Locomotion velocity, hab. session 2	0.4	0.6	0.8	-0.9	0.8	-0.6	0.7
Novel to familiar place preference ratio	0.6	0.7	1.1	0.5	-0.6	1.1	-1.0
Novelty place preference	0.7	0.7	1.3	0.6	-0.6	1.1	-1.0
Time in novel zone, NPP test	0.9	1.0	2.1	0.6	-0.5	1.5	-1.1
Total zone transitions, NPP test	0.6	0.8	1.7	-1.1	0.2	-1.3	0.4
Total locomotion distance, NPP test	0.1	0.2	0.4	-0.6	-0.2	-0.6	-0.1
Locomotion velocity, NPP test	0.4	0.6	1.5	-0.8	-0.4	-1.2	-0.0
Intraocular pressure	0.0	0.1	0.1	0.3	0.1	-0.1	-0.3
Delta distance traveled before/after self-admin	1.1	1.2	1.5	1.0	-1.2	1.0	-1.2
Delta ambulatory time before/after self-admin	1.0	1.1	1.5	0.9	-1.2	0.9	-1.2
Parametrial fat weight	19.1	37.3	55.6	-7.5	6.1	-5.4	5.2
Pavlov. Cond. lever latency	1.0	1.2	2.7	1.2	-0.6	1.6	-0.7
Pavlov. Cond. magazine entry latency	0.6	0.8	1.3	-1.1	0.6	-1.1	0.5
Pavlov. Cond. change in total contacts	1.3	1.4	2.4	-1.6	1.3	-0.9	0.8
Pavlov. Cond. index score	0.9	1.2	2.0	-1.4	0.8	-1.3	0.7
Pavlov. Cond. latency score	0.8	1.0	1.7	-1.3	0.8	-1.2	0.6
Pavlov. Cond. lever contacts	1.2	1.4	1.9	-1.3	1.1	-1.4	0.9
Pavlov. Cond. magazine entry number	0.5	0.6	1.3	1.1	-0.5	0.8	-0.3
Pavlov. Cond. intertrial magazine entries	1.4	1.7	3.9	-2.0	0.5	-1.5	0.4
Pavlov. Cond. lever-magazine prob. diff.	0.9	1.1	1.9	-1.4	0.8	-1.2	0.6
Pavlov. Cond. response bias	0.8	1.0	1.7	-1.2	0.7	-1.3	0.6
Pavlov. Cond. lever latency	0.3	0.4	1.2	1.1	-0.6	0.2	-0.2
Pavlov. Cond. magazine entry latency	0.4	0.4	0.8	0.9	-0.2	0.8	-0.5
Pavlov. Cond. change in total contacts	0.1	0.2	0.4	-0.3	0.4	0.7	0.1
Pavlov. Cond. index score	0.0	0.0	0.1	-0.2	0.1	0.3	-0.2
Pavlov. Cond. latency score	0.0	0.0	0.1	-0.2	0.1	0.3	-0.1
Pavlov. Cond. lever contacts	0.2	0.3	0.7	-0.8	0.5	-0.0	0.2
Pavlov. Cond. magazine entry number	0.1	0.1	0.2	-0.4	0.1	-0.3	0.2
Pavlov. Cond. intertrial magazine entries	4.0	5.2	8.0	-2.8	1.8	-2.5	1.9
Pavlov. Cond. lever-magazine prob. diff.	0.0	0.0	0.1	-0.0	0.1	0.3	-0.2
Pavlov. Cond. response bias	0.1	0.1	0.3	-0.2	0.2	0.6	-0.3
Time in closed arm before self-admin	0.1	0.1	0.3	0.5	0.3	0.2	0.3
Time in closed arm after self-admin	0.2	0.2	0.4	0.6	-0.6	0.2	-0.3
Time in open arm before self-admin	0.6	0.6	0.8	0.9	-0.8	0.7	-0.7
Time in open arm after self-admin	0.7	0.8	2.5	0.7	0.3	1.6	-0.3
Bone: periosteal estimation	7.0	14.5	21.2	-4.6	3.5	-3.8	3.2
Bone: periosteal perimeter	9.7	16.2	19.7	-4.4	4.2	-3.6	3.8
Bone: post-yield work	0.4	0.6	1.3	-1.1	0.3	-1.0	-0.0
Progressive ratio test 1 active lever presses	0.7	0.7	1.2	1.1	-1.0	0.5	-0.7
Progressive ratio test 1 breakpoint	0.5	0.5	1.2	1.1	-0.7	0.5	-0.4
Progressive ratio test 1 inactive lever presses	0.5	0.6	0.8	0.8	-0.9	0.6	-0.7
Progressive ratio test 2 active lever presses	0.8	0.8	1.3	-0.7	0.9	-0.8	1.1
Progressive ratio test 2 breakpoint	0.8	0.9	1.4	-0.7	0.9	-1.0	1.2
Progressive ratio test 2 inactive lever presses	0.0	0.0	0.1	-0.3	-0.1	0.0	-0.1
Incentive Sensitization - Responses	2.3	2.4	2.6	-1.5	1.6	-1.4	1.6
Incentive Sensitization - Breakpoint	1.9	1.9	2.2	-1.4	1.5	-1.3	1.5
Sum of active levers in priming session hrs 5-6	0.0	0.0	0.1	0.1	0.1	0.3	-0.0
Progressive ratio	1.9	2.2	3.4	1.8	-1.4	1.4	-1.1
Food seeking constrained by brief footshock	5.3	6.5	11.2	3.4	-2.2	2.4	-2.0
Seeking ratio, punishment vs. effort	0.1	0.1	0.1	0.2	-0.3	-0.1	-0.3
Retroperitoneal fat weight	33.7	110.7	165.2	-12.9	9.9	-10.2	8.7
Reaction time number correct	0.3	0.5	0.8	-0.8	0.9	-0.2	0.7
Reaction time mean minus median	0.2	0.3	0.6	0.1	0.5	-0.5	0.7
Reaction time mean minus median AUC	0.8	1.0	2.1	-0.3	1.0	-1.0	1.5
Reaction time num false alarms	0.7	0.9	1.9	-1.3	-0.1	-1.4	-0.0
Reaction time num false alarms AUC	1.1	1.5	3.0	-1.6	0.4	-1.7	0.4
Reaction time trials correct on left	0.3	0.5	0.8	-0.8	0.9	-0.2	0.7
Reaction time trials on left	0.3	0.4	0.8	-0.7	0.9	-0.1	0.7
Reaction time mean	0.8	1.1	3.5	1.9	-0.6	0.7	-0.2
Reaction time mean AUC	0.8	1.1	3.7	1.9	-0.6	0.7	-0.2
Median of all reaction times	1.0	1.3	4.2	2.0	-0.7	0.7	-0.3
Reaction time omissions	0.4	0.6	1.2	1.1	-0.3	1.0	-0.4
Reaction time false alarm rate	0.6	0.8	2.2	-1.0	-0.2	-1.5	-0.1
Reaction time premature initiation rate	0.1	0.1	0.4	0.1	-0.1	-0.6	0.3
Reaction time premature initiations	0.3	0.5	0.6	-0.5	0.6	-0.8	0.8
Std. dev. reaction times	0.1	0.2	0.3	0.3	0.4	-0.3	0.6
Reaction time trials completed	0.3	0.4	0.8	-0.7	0.9	-0.1	0.7
Reaction time trials AUC	0.5	0.7	1.1	-1.0	1.1	-0.3	0.8
Run reversals in cocaine runway, females	0.4	0.3	0.8	0.9	-0.1	0.7	-0.2
Run reversals in cocaine runway, males	0.1	0.1	0.3	0.1	-0.5	-0.4	0.1
Latency to leave start box in cocaine runway	0.8	0.9	1.9	1.0	0.8	1.4	0.4
Latency to leave start box in cocaine runway, F	0.4	0.4	0.7	0.1	0.9	0.8	0.5
Latency to leave start box in cocaine runway, M	0.4	0.4	0.7	0.8	0.4	0.6	0.4
Std. dev. time between licks in bursts	2.6	3.1	3.7	1.4	-1.7	1.9	-1.9
Total sessions with >9 infusions	0.2	0.3	0.7	0.5	-0.9	-0.1	-0.3
Short access day 1 total inactive lever presses	1.7	1.9	2.7	1.0	-1.6	1.1	-1.7
Short access day 10 total inactive lever presses	2.4	2.6	5.0	-2.2	1.0	-1.9	1.1
Short access day 1 total infusions	1.0	1.1	1.9	1.1	-1.4	0.5	-1.0
Short access day 10 total infusions	1.4	1.6	2.8	1.7	-1.1	1.2	-1.0
Short access total infusions	0.9	1.1	1.8	1.3	-1.2	0.6	-0.8
Short access day 1 locomotion	0.2	0.2	0.3	0.6	-0.5	0.2	-0.2
Short access day 10 total locomotion	0.6	0.6	1.1	1.0	-0.8	0.7	-0.6
Short access total locomotion	0.6	0.6	1.3	1.1	-1.1	0.2	-0.4
One hour access (0.3 mA shock)	0.4	0.5	0.9	1.0	-0.4	0.8	-0.4
Compulsive drug intake	0.1	0.1	0.2	-0.2	-0.3	-0.2	-0.5
One hour access (shock baseline)	0.6	0.7	1.3	1.2	-0.5	1.0	-0.4
Social response proportion	0.4	0.4	0.6	-0.8	-0.5	-0.7	-0.6
Social responses	1.3	1.7	2.9	-1.7	1.4	-1.1	1.0
Social time	0.2	0.2	0.5	-0.4	0.7	-0.0	0.6
Soleus weight	4.0	11.8	14.7	-3.8	2.9	-3.8	3.2
Bone: stiffness	2.8	4.4	7.3	-2.7	1.6	-2.4	1.5
Tibialis anterior weight	0.1	0.5	0.9	-1.0	0.8	-0.2	0.5
Time to tail flick, vehicle, before self-admin	0.1	0.2	0.3	-0.3	-0.2	0.5	-0.5
Time to tail flick, vehicle, after self-admin	0.6	0.6	0.8	-0.9	0.8	-0.5	0.8
Time to tail flick, test, before self-admin	0.3	0.3	0.5	0.7	-0.7	-0.1	-0.3
Time to tail flick, test, after self-admin	0.1	0.1	0.3	-0.1	0.1	0.6	-0.2
Delta time to tail flick, vehicle, before/after SA	3.7	3.7	5.4	-1.5	2.2	-1.5	2.3
Delta time to tail flick, test, before/after SA	0.5	0.5	1.2	-1.1	0.8	0.2	0.1
Tibia length	0.3	0.9	1.6	-1.3	0.7	-1.0	0.6
Ambulatory time before self-admin	0.2	0.2	0.5	0.1	0.0	-0.7	0.5
Ambulatory time after self-admin	1.2	1.3	2.3	1.5	-1.3	0.5	-0.9
Bone: tissue strength	0.6	0.6	1.4	0.9	-0.2	1.2	-0.4
Total heroin consumption	5.8	6.8	9.0	-2.3	3.0	-2.2	2.8
Bone: trabecular number	1.0	1.6	3.0	-1.7	1.0	-1.3	0.7
Bone: trabecular spacing	4.1	5.3	7.1	2.7	-1.9	2.5	-2.1
Bone: trabecular thickness	11.5	13.7	17.9	-4.2	3.6	-3.6	3.4
Bone: trabecular tissue density	2.1	2.9	3.7	1.5	-1.9	1.5	-1.8
Water consumed over 24 hours	0.2	0.2	0.4	-0.7	0.2	-0.3	0.4
Number of responses in last shaping day	0.8	0.8	1.1	1.0	-1.1	0.7	-0.9