Hub : Genes

Cspg5

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 PL gene expression Cspg5 0.56 0.23 1.3e-12 0.1 0.11 0.11 0.11 2.0e-11 4.1e-12 2.2e-12 7.0e-12
2 LHb gene expression Cspg5 0.83 0.12 2.1e-10 0.23 0.22 0.25 0.25 3.4e-06 6.6e-06 1.2e-06 1.3e-06
3 NAcc gene expression Cspg5 0.18 0.19 0.0e+00 0.12 0.12 0.12 0.12 2.5e-17 3.2e-17 1.8e-17 2.0e-17
4 Brain gene expression Cspg5 0.2 0.13 5.6e-17 0.17 0.18 0.17 0.18 6.5e-16 1.3e-16 8.7e-16 2.7e-16
5 pVTA gene expression Cspg5 0.32 0.16 0.0e+00 0.32 0.33 0.33 0.33 3.4e-26 1.5e-27 3.9e-27 2.7e-27
6 Brain isoform ratio NM_019284.3 0.04 0.04 2.3e-04 0.02 0.04 0.03 0.03 2.5e-03 1.8e-04 1.7e-03 1.5e-03
7 BLA gene expression Cspg5 0.19 0.15 4.8e-09 0.14 0.15 0.13 0.14 9.5e-08 2.2e-08 2.6e-07 1.3e-07
8 NAcc isoform ratio NM_133652.2 0.04 0.04 3.4e-05 0.03 0.03 0.01 0.03 5.6e-05 4.4e-05 8.6e-03 6.2e-05
9 Brain isoform ratio NM_133652.2 0.04 0.04 3.1e-04 0.02 0.04 0.02 0.02 3.1e-03 2.2e-04 2.5e-03 2.2e-03
10 NAcc isoform ratio NM_019284.3 0.03 0.03 6.9e-05 0.02 0.03 0.02 0.02 1.3e-04 9.1e-05 1.2e-04 2.1e-04
11 Adipose mRNA stability Cspg5 0.03 0.02 9.5e-04 0.01 0.01 0.01 0.01 2.2e-02 1.2e-02 3.3e-02 4.9e-02
12 Brain intron excision ratio chr8_119106408_119112556 0.04 0.04 3.3e-04 0.03 0.03 0.03 0.03 1.5e-03 3.4e-04 9.3e-04 1.6e-03
13 Brain intron excision ratio chr8_119106489_119112556 0.05 0.04 1.9e-04 0.03 0.04 0.03 0.03 8.6e-04 1.8e-04 4.7e-04 9.1e-04
14 IL gene expression Cspg5 0.48 0.25 9.5e-08 0.24 0.25 0.24 0.24 2.3e-06 1.1e-06 1.7e-06 1.9e-06
15 OFC gene expression Cspg5 0.74 0.18 1.9e-05 0.15 0.09 0.11 0.12 2.6e-04 3.9e-03 1.4e-03 9.3e-04
16 PL isoform ratio NM_133652.2 0.02 0.03 6.3e-03 0.01 0.01 0.01 0.01 1.7e-02 6.5e-02 3.3e-02 4.2e-02
17 Liver gene expression Cspg5 0.13 0.09 4.4e-14 0.12 0.11 0.1 0.11 2.2e-13 1.4e-12 1.0e-11 1.3e-12
18 Adipose gene expression Cspg5 0.26 0.14 0.0e+00 0.23 0.24 0.24 0.23 5.6e-25 1.4e-26 3.2e-26 8.6e-26
19 Brain mRNA stability Cspg5 0.04 0.04 6.5e-04 0.04 0.04 0.03 0.04 2.3e-04 3.0e-04 3.7e-04 2.0e-04
20 BLA intron excision ratio chr8_119106489_119112556 0.08 0.08 7.2e-04 0.05 0.05 0.05 0.05 1.3e-03 1.5e-03 1.6e-03 1.9e-03
21 BLA intron excision ratio chr8_119106408_119112556 0.08 0.08 9.6e-04 0.05 0.04 0.04 0.04 1.7e-03 1.9e-03 2.0e-03 2.3e-03
22 PL isoform ratio NM_019284.3 0.03 0.03 4.9e-03 0.01 0.01 0.01 0.01 1.3e-02 4.4e-02 8.7e-03 2.6e-02

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22
Bone: apparent density0.00.00.1-0.0-0.1-0.0-0.0-0.00.0-0.0-0.0-0.00.0-0.10.1-0.1-0.10.20.2-0.0-0.10.0-0.00.00.4
Area under the delay curve1.51.72.21.51.21.31.41.4-1.41.41.41.4-1.41.4-1.41.41.41.21.21.51.41.21.2-1.20.3
BMI with tail0.10.31.5-0.8-0.9-0.8-0.6-0.50.4-0.4-0.4-0.40.4-0.40.4-0.4-0.3-0.5-0.5-0.4-0.1-0.4-0.40.4-1.2
BMI without tail0.51.72.7-1.4-1.6-1.5-1.4-1.31.2-1.2-1.3-1.21.2-1.21.2-1.2-1.2-1.5-1.5-1.1-1.0-1.2-1.21.21.3
Body weight4.620.024.8-5.0-4.8-4.9-4.8-4.64.6-4.6-4.6-4.64.6-4.64.6-4.6-4.5-4.4-4.4-4.6-4.2-4.3-4.34.30.5
Weight adjusted by age0.00.00.20.0-0.3-0.1-0.1-0.10.0-0.0-0.1-0.00.1-0.00.0-0.0-0.0-0.4-0.4-0.1-0.1-0.3-0.30.30.5
Bone surface0.10.20.50.40.40.40.40.5-0.50.50.50.5-0.50.5-0.50.50.50.70.70.50.50.50.5-0.5-0.5
Bone volume0.10.10.30.20.20.20.20.3-0.30.30.30.3-0.30.3-0.30.30.30.60.60.30.30.30.3-0.3-0.4
Breakpoint value in progressive ratio session0.10.10.20.40.30.30.40.4-0.40.40.30.4-0.40.4-0.40.40.40.30.30.40.30.20.2-0.20.2
Number of licking bursts0.20.31.20.70.70.60.60.5-0.50.50.50.5-0.50.5-0.50.50.50.60.60.40.40.50.5-0.5-1.1
Context. condit. distance diff. score0.00.00.10.0-0.00.00.00.0-0.00.00.00.0-0.00.0-0.00.00.0-0.0-0.00.00.00.0-0.00.0-0.3
Locomotion velocity, session 10.10.10.10.10.00.20.30.3-0.30.30.30.3-0.30.3-0.30.30.30.10.10.30.40.10.1-0.10.2
Locomotion distance, session 10.91.12.0-1.3-1.4-1.2-1.1-1.00.9-0.9-1.0-0.91.0-0.90.9-0.9-0.9-1.2-1.2-0.9-0.7-1.1-1.01.01.4
Locomotion velocity, session 20.30.40.60.40.40.50.60.6-0.70.70.60.7-0.70.7-0.70.70.70.40.40.70.80.60.6-0.6-0.3
Locomotion distance, session 20.10.11.1-0.1-0.2-0.00.10.2-0.20.30.20.3-0.20.3-0.30.30.3-0.0-0.00.20.40.00.1-0.11.0
Locomotion velocity, session 30.10.10.4-0.5-0.6-0.5-0.4-0.30.3-0.3-0.3-0.30.3-0.30.3-0.3-0.2-0.1-0.1-0.1-0.1-0.3-0.20.20.6
Locomotion distance, session 30.91.01.40.90.80.90.91.0-1.01.01.01.0-1.01.0-1.01.01.01.21.21.01.21.11.2-1.2-0.2
Stereotopy head waving bouts, day 30.10.11.5-0.10.0-0.1-0.1-0.10.1-0.1-0.1-0.10.1-0.10.1-0.1-0.1-0.2-0.2-0.2-0.1-0.1-0.10.1-1.2
Stereotopy head waving duration, day 30.20.20.4-0.4-0.3-0.4-0.4-0.50.5-0.5-0.5-0.50.5-0.50.5-0.5-0.5-0.6-0.6-0.6-0.6-0.5-0.50.5-0.4
Locomotion velocity, session 70.30.31.2-0.3-0.4-0.4-0.5-0.50.6-0.6-0.5-0.60.5-0.60.6-0.6-0.6-0.2-0.2-0.7-0.6-0.3-0.40.41.1
Locomotion distance, session 70.70.81.41.01.00.90.80.9-0.80.80.90.8-0.90.8-0.80.80.81.21.20.60.81.11.1-1.10.1
Stereotopy head waving bouts, day 70.00.00.6-0.0-0.1-0.00.10.0-0.10.10.00.1-0.00.1-0.10.10.1-0.2-0.20.30.0-0.0-0.10.10.8
Stereotopy head waving duration, day 70.40.41.4-0.7-0.8-0.7-0.6-0.60.6-0.6-0.6-0.60.6-0.60.6-0.6-0.6-0.9-0.9-0.4-0.6-0.6-0.70.71.2
Locomotion velocity, session 80.20.30.7-0.7-0.8-0.7-0.6-0.50.5-0.4-0.5-0.40.5-0.40.4-0.4-0.4-0.6-0.6-0.3-0.2-0.5-0.40.40.7
Locomotion distance, session 80.20.32.8-0.7-0.9-0.6-0.5-0.40.4-0.3-0.4-0.40.4-0.30.3-0.3-0.3-0.6-0.6-0.3-0.1-0.3-0.30.31.7
Degree of sensitization distance1.21.31.9-0.9-0.9-1.0-1.1-1.21.2-1.2-1.2-1.21.2-1.21.2-1.2-1.2-1.0-1.0-1.4-1.3-1.1-1.21.20.6
Degree of sensitization stereotypy0.20.22.0-0.3-0.4-0.3-0.2-0.20.2-0.2-0.2-0.20.2-0.20.2-0.2-0.2-0.4-0.40.1-0.2-0.3-0.40.41.4
Conditioned locomotion3.03.53.92.02.02.01.91.9-1.91.91.91.9-1.91.9-1.91.91.91.91.92.01.81.91.9-1.9-0.0
Cocaine response after cond. corrected0.20.30.6-0.5-0.4-0.5-0.5-0.50.5-0.5-0.5-0.50.5-0.50.5-0.5-0.5-0.6-0.6-0.6-0.5-0.5-0.50.5-0.8
Cocaine response after cond. not corrected1.61.82.0-1.4-1.3-1.4-1.4-1.41.4-1.4-1.4-1.41.4-1.41.4-1.4-1.4-1.4-1.4-1.4-1.3-1.4-1.41.4-0.5
Cocaine response before conditioning1.11.31.9-1.3-1.4-1.3-1.2-1.11.1-1.1-1.1-1.11.1-1.11.1-1.1-1.1-1.0-1.0-1.0-1.0-1.2-1.21.20.6
Saline control response0.81.11.4-1.0-1.0-1.0-1.0-1.11.1-1.1-1.1-1.11.1-1.11.1-1.1-1.1-0.8-0.8-1.1-1.2-1.2-1.21.20.5
Bone: connectivity density0.20.40.50.70.60.70.70.6-0.60.60.60.6-0.60.6-0.60.60.60.70.70.70.50.50.5-0.50.6
Bone: cortical apparent density0.10.20.40.40.40.50.50.5-0.50.50.50.5-0.50.5-0.50.50.50.40.40.60.50.40.4-0.40.2
Bone: cortical area0.20.31.50.50.50.50.50.5-0.50.50.50.5-0.50.5-0.50.50.50.40.40.30.50.50.5-0.5-1.2
Bone: cortical porosity0.20.22.50.50.30.40.40.3-0.30.30.30.3-0.30.3-0.30.30.30.30.30.30.10.20.2-0.21.6
Bone: cortical porosity0.10.11.60.40.30.40.30.2-0.20.20.20.2-0.20.2-0.20.20.20.30.30.10.00.20.2-0.21.3
Bone: cortical thickness0.10.21.9-0.3-0.2-0.4-0.3-0.30.3-0.3-0.3-0.30.3-0.30.3-0.3-0.3-0.3-0.3-0.4-0.3-0.3-0.30.3-1.4
Bone: cortical thickness0.00.00.00.10.20.10.00.0-0.00.00.00.0-0.00.0-0.00.00.00.20.2-0.1-0.00.10.1-0.1-0.2
Bone: cortical tissue density0.10.20.40.40.40.50.50.5-0.50.50.50.5-0.50.5-0.50.50.50.40.40.60.50.30.3-0.30.1
Condit. Reinf. active minus inactive responses0.10.10.3-0.2-0.1-0.2-0.3-0.40.4-0.4-0.4-0.40.4-0.40.4-0.4-0.4-0.4-0.4-0.5-0.5-0.4-0.40.40.1
Condit. Reinf. active-inactive response ratio0.30.30.5-0.4-0.3-0.4-0.5-0.60.6-0.6-0.6-0.60.6-0.60.6-0.6-0.6-0.5-0.5-0.7-0.7-0.7-0.70.7-0.3
Condit. Reinf. active responses0.00.00.10.20.30.20.10.1-0.00.00.10.0-0.10.0-0.00.00.0-0.0-0.00.2-0.00.10.1-0.1-0.0
Condit. Reinf. inactive responses0.60.71.40.80.80.80.80.9-0.90.90.90.8-0.90.9-0.80.80.90.70.71.20.91.01.0-1.0-0.1
Incentive salience index mean0.00.00.10.20.20.20.20.2-0.20.20.20.2-0.20.2-0.20.20.20.10.10.20.20.20.2-0.2-0.1
Condit. Reinf. lever presses1.41.92.31.31.21.31.41.4-1.41.41.41.4-1.41.5-1.51.51.51.41.41.41.51.31.4-1.4-0.8
Condit. Reinf. active minus inactive responses1.41.82.3-1.5-1.4-1.5-1.5-1.41.4-1.4-1.4-1.41.4-1.41.4-1.4-1.4-1.2-1.2-1.5-1.3-1.3-1.31.3-0.7
Condit. Reinf. active-inactive response ratio1.41.62.0-1.4-1.4-1.4-1.4-1.31.3-1.3-1.3-1.31.3-1.31.3-1.3-1.3-1.2-1.2-1.2-1.2-1.2-1.21.2-0.5
Condit. Reinf. active responses1.21.72.2-1.5-1.4-1.4-1.4-1.41.4-1.3-1.4-1.31.4-1.31.3-1.3-1.3-1.1-1.1-1.4-1.3-1.3-1.31.3-1.0
Condit. Reinf. inactive responses0.10.10.80.30.30.40.30.3-0.30.30.30.3-0.30.3-0.30.30.30.40.40.30.30.20.2-0.2-0.9
Condit. Reinf. lever presses2.02.73.4-1.8-1.8-1.8-1.8-1.71.7-1.7-1.7-1.71.7-1.71.7-1.7-1.7-1.7-1.7-1.7-1.6-1.6-1.51.50.4
Condit. Reinf. lever reinforcers received1.62.22.6-1.6-1.5-1.6-1.6-1.51.5-1.5-1.5-1.51.5-1.51.5-1.5-1.5-1.3-1.3-1.6-1.4-1.5-1.51.5-0.8
Conditioned reinforcement - actives1.93.23.71.91.81.91.91.9-1.91.91.81.9-1.91.9-1.91.91.91.71.71.91.81.51.5-1.5-1.3
Conditioned reinforcement - inactives2.03.03.51.71.91.71.71.7-1.71.71.71.7-1.71.7-1.71.71.71.81.81.71.71.81.8-1.8-1.4
Conditioned locomotion0.40.50.70.60.60.80.70.7-0.80.80.70.8-0.70.8-0.80.80.80.60.60.80.70.50.5-0.5-0.1
Patch foraging indifference point 0 sec1.12.13.6-1.4-1.5-1.3-1.4-1.41.3-1.3-1.4-1.31.4-1.31.3-1.3-1.3-1.5-1.5-1.5-1.4-1.6-1.61.61.9
Patch foraging indifference point AUC0.00.10.9-0.1-0.2-0.3-0.2-0.10.2-0.2-0.1-0.20.1-0.10.2-0.2-0.1-0.2-0.20.0-0.1-0.1-0.10.10.9
Delay disc. indifference point, 0s delay0.00.00.10.00.1-0.00.00.0-0.00.10.00.0-0.00.0-0.10.10.1-0.1-0.10.10.1-0.00.1-0.1-0.2
Delay disc. indifference point, 16s delay0.80.91.01.00.90.91.01.0-1.01.01.01.0-1.01.0-1.01.01.00.90.91.01.01.00.9-0.90.0
Delay disc. indifference point, 2s delay0.20.30.60.60.30.40.50.5-0.50.60.50.5-0.50.5-0.50.50.50.40.40.70.50.30.4-0.40.8
Delay disc. indifference point, 24s delay0.80.91.11.10.90.91.01.0-1.01.01.01.0-1.01.0-1.01.01.01.01.01.01.01.01.0-1.00.3
Delay disc. indifference point, 4s delay1.51.62.21.41.11.21.41.4-1.41.41.31.4-1.31.4-1.41.41.41.21.21.51.31.11.1-1.10.2
Delay disc. indifference point, 8s delay1.72.02.41.51.31.41.51.5-1.51.51.51.5-1.51.5-1.51.51.51.41.41.61.41.31.4-1.40.0
Indifference point function ln k0.30.50.80.40.60.60.60.7-0.70.70.70.7-0.70.7-0.70.70.70.70.70.40.80.90.9-0.9-0.9
Indifference point function log k0.30.50.80.40.60.60.60.7-0.70.70.70.7-0.70.7-0.70.70.70.70.70.40.80.90.9-0.9-0.9
Patch foraging total patch changes 0 sec1.22.22.9-1.5-1.6-1.3-1.4-1.41.4-1.4-1.4-1.41.4-1.41.4-1.4-1.4-1.5-1.5-1.6-1.4-1.7-1.71.71.5
Patch foraging total patch changes 12 sec1.01.31.5-1.2-1.1-1.1-1.1-1.11.1-1.1-1.1-1.11.1-1.11.1-1.1-1.1-1.1-1.1-1.2-1.1-1.2-1.11.10.7
Patch foraging total patch changes 18 sec1.92.93.4-1.6-1.5-1.6-1.7-1.71.7-1.7-1.7-1.71.7-1.71.7-1.7-1.7-1.6-1.6-1.8-1.8-1.8-1.81.81.2
Patch foraging total patch changes 24 sec2.03.54.0-2.0-1.9-1.9-1.9-1.91.9-1.9-1.9-1.91.9-1.91.9-1.9-1.9-1.8-1.8-2.0-1.8-1.9-1.91.90.7
Patch foraging total patch changes 6 sec0.30.53.3-0.5-0.7-0.5-0.5-0.60.5-0.5-0.6-0.50.6-0.50.5-0.5-0.5-0.7-0.7-0.6-0.6-0.8-0.80.81.8
Patch foraging time to switch 0 sec0.10.30.40.70.70.60.60.5-0.50.50.50.5-0.50.5-0.50.50.50.50.50.60.40.50.5-0.5-0.2
Patch foraging water rate 0 sec0.10.30.5-0.5-0.5-0.5-0.5-0.50.5-0.5-0.5-0.50.5-0.50.5-0.5-0.5-0.5-0.5-0.7-0.4-0.5-0.50.5-0.5
Patch foraging water rate 12 sec0.20.40.8-0.7-0.5-0.6-0.6-0.60.6-0.6-0.6-0.60.6-0.60.6-0.6-0.6-0.6-0.6-0.9-0.5-0.5-0.40.4-0.8
Patch foraging water rate 18 sec0.10.10.8-0.3-0.2-0.3-0.3-0.20.2-0.2-0.2-0.20.2-0.20.2-0.2-0.2-0.2-0.2-0.4-0.1-0.1-0.10.1-0.9
Patch foraging water rate 24 sec0.71.01.2-0.9-1.0-1.0-1.0-1.01.0-1.0-1.0-1.01.0-1.01.0-1.0-1.0-1.1-1.1-1.0-1.0-1.0-1.01.0-0.0
Patch foraging water rate 6 sec0.40.51.0-0.9-0.7-0.8-0.8-0.80.8-0.8-0.8-0.80.8-0.80.8-0.8-0.7-0.6-0.6-1.0-0.6-0.5-0.50.50.1
Seeking ratio, delayed vs. immediate footshock2.02.42.91.71.61.61.61.6-1.61.61.61.6-1.61.6-1.61.61.61.51.51.51.61.61.6-1.6-0.3
Distance traveled before self-admin0.40.64.00.70.80.60.60.6-0.60.60.60.6-0.60.6-0.60.60.60.80.80.30.60.80.8-0.8-2.0
Distance traveled after self-admin0.30.31.70.60.60.50.50.5-0.50.40.50.5-0.50.5-0.50.50.50.60.60.10.50.70.7-0.7-1.3
Extensor digitorum longus weight0.20.83.90.70.70.80.80.8-0.80.80.80.8-0.80.8-0.80.80.81.11.10.70.90.70.7-0.7-2.0
Bone: elastic displacement0.10.11.2-0.2-0.1-0.2-0.2-0.20.2-0.2-0.2-0.20.2-0.20.2-0.2-0.2-0.1-0.1-0.3-0.3-0.3-0.30.3-1.1
Bone: elastic work0.30.40.5-0.7-0.7-0.7-0.7-0.60.6-0.6-0.6-0.60.6-0.60.6-0.6-0.6-0.6-0.6-0.7-0.5-0.5-0.50.5-0.6
Bone: endosteal estimation0.00.10.9-0.1-0.1-0.2-0.2-0.20.3-0.3-0.2-0.30.3-0.30.3-0.3-0.3-0.2-0.2-0.5-0.3-0.1-0.20.20.9
Bone: endosteal perimeter1.12.42.71.51.51.61.61.6-1.61.61.61.6-1.61.6-1.61.61.61.31.31.51.71.61.6-1.6-0.4
Epididymis fat weight0.31.01.2-1.0-0.8-1.0-1.1-1.11.1-1.1-1.1-1.11.1-1.11.1-1.1-1.1-0.9-0.9-0.9-1.1-0.9-0.90.9-0.9
Delta time in closed arm before/after self-admin0.60.60.90.50.90.60.70.7-0.70.70.70.7-0.70.7-0.70.70.70.90.90.60.70.90.9-0.9-1.0
Delta time in open arm before/after self-admin0.40.41.5-0.4-0.6-0.5-0.6-0.60.6-0.6-0.6-0.60.6-0.60.6-0.6-0.6-0.6-0.6-0.7-0.6-0.5-0.50.51.2
Diff in mean of infusions in LGA sessions0.00.10.5-0.1-0.2-0.2-0.1-0.10.0-0.0-0.1-0.00.1-0.00.0-0.0-0.0-0.3-0.30.2-0.1-0.3-0.30.3-0.7
Delay discount exponential model param1.71.92.4-1.5-1.2-1.3-1.5-1.51.5-1.5-1.4-1.51.4-1.51.5-1.5-1.5-1.3-1.3-1.5-1.4-1.3-1.31.3-0.3
Extinction: sum of active levers before priming0.00.00.60.30.20.20.20.2-0.20.20.20.2-0.20.2-0.20.20.20.10.10.10.10.00.0-0.00.8
Active lever presses in extinction session 60.10.10.6-0.2-0.4-0.2-0.3-0.30.3-0.3-0.3-0.30.3-0.30.3-0.3-0.3-0.3-0.3-0.3-0.3-0.4-0.40.40.8
Bone: final force1.01.62.2-1.3-1.4-1.4-1.3-1.31.2-1.2-1.3-1.21.3-1.21.2-1.2-1.2-1.5-1.5-1.2-1.2-1.3-1.31.30.3
Bone: final moment1.21.92.6-1.5-1.5-1.5-1.4-1.41.4-1.3-1.4-1.31.4-1.31.3-1.3-1.3-1.6-1.6-1.4-1.3-1.4-1.41.40.3
Food consumed during 24 hour testing period1.31.82.2-1.5-1.4-1.4-1.4-1.41.3-1.3-1.4-1.31.4-1.31.3-1.3-1.3-1.4-1.4-1.4-1.3-1.3-1.31.30.3
Glucose0.91.41.7-1.3-1.3-1.3-1.3-1.21.2-1.2-1.2-1.21.2-1.21.2-1.2-1.2-1.0-1.0-1.2-1.1-1.1-1.11.10.6
Heart weight1.52.33.0-1.7-1.5-1.6-1.6-1.51.5-1.5-1.5-1.51.5-1.51.5-1.5-1.5-1.7-1.7-1.5-1.5-1.5-1.51.5-1.0
Delay discount hyperbolic model param1.92.22.7-1.6-1.3-1.4-1.6-1.61.6-1.6-1.5-1.61.5-1.61.6-1.6-1.6-1.4-1.4-1.6-1.5-1.3-1.41.4-0.3
Intermittent access intake day 1-15 change0.71.51.81.31.31.31.21.2-1.21.21.21.2-1.21.2-1.21.21.21.31.31.21.21.31.3-1.3-0.8
Intermittent access intake escalation1.02.12.41.51.51.51.51.5-1.41.41.51.4-1.51.4-1.41.41.41.51.51.41.41.51.5-1.5-0.7
Intermittent access intake escalation 20.30.41.10.50.80.60.50.5-0.50.50.50.5-0.50.5-0.50.50.50.70.70.40.50.70.7-0.7-1.0
Intermitt. access day 1 inactive lever presses0.00.10.40.30.20.30.30.3-0.30.30.30.3-0.30.3-0.30.40.40.20.20.40.40.20.2-0.2-0.6
Intermitt. access day 15 inactive lever presses0.91.82.21.51.31.41.41.4-1.41.41.41.4-1.41.4-1.41.41.41.31.31.41.41.11.1-1.1-1.0
Intermitt. access escalation Index0.00.11.20.1-0.10.10.10.1-0.10.10.10.1-0.10.1-0.10.10.10.00.00.10.10.00.0-0.01.1
Intermittent access day 1 total infusions0.20.40.60.80.60.70.70.7-0.70.70.70.7-0.70.7-0.70.70.70.50.50.60.60.40.4-0.40.5
Intermittent access day 15 total infusions1.62.42.91.71.51.71.61.6-1.61.61.61.6-1.61.6-1.61.61.61.51.51.61.61.41.4-1.40.2
Intermittent access terminal intake (last 3 days)1.21.62.11.41.21.41.41.4-1.41.41.31.4-1.31.4-1.41.41.31.21.21.31.31.01.0-1.00.8
Intermittent access total infusions1.82.22.71.61.41.61.61.6-1.61.61.61.6-1.61.6-1.61.61.61.31.31.61.51.21.2-1.20.5
Intermittent access day 1 locomotion0.10.22.4-0.1-0.3-0.2-0.2-0.20.2-0.2-0.2-0.20.2-0.20.2-0.2-0.2-0.4-0.4-0.3-0.3-0.4-0.40.41.5
Intermittent access day 15 total locomotion0.40.70.90.81.00.90.80.8-0.80.80.80.8-0.80.8-0.80.80.80.90.90.80.80.80.8-0.80.4
Intermittent access total locomotion1.01.21.41.11.11.21.11.1-1.11.11.11.1-1.11.1-1.11.11.11.01.01.11.10.90.9-0.90.8
Intermittent access standard deviation0.00.00.20.10.10.10.00.1-0.00.00.00.0-0.00.0-0.00.00.0-0.0-0.00.00.0-0.1-0.10.10.5
Left kidney weight0.62.93.9-2.0-1.9-1.9-1.8-1.81.8-1.8-1.8-1.81.8-1.81.8-1.8-1.7-1.6-1.6-1.6-1.6-1.6-1.61.60.2
Right kidney weight0.31.21.7-1.3-1.3-1.2-1.2-1.11.1-1.1-1.1-1.11.1-1.11.1-1.1-1.1-1.0-1.0-1.0-1.0-1.2-1.21.20.2
Cocaine induced anxiety0.20.33.0-0.3-0.8-0.4-0.3-0.30.2-0.2-0.3-0.20.3-0.20.2-0.2-0.2-0.8-0.8-0.1-0.3-0.7-0.70.71.7
Post-drug Anxiety0.10.11.00.0-0.3-0.00.00.0-0.10.10.00.1-0.00.1-0.10.10.1-0.3-0.30.20.1-0.3-0.30.31.0
Baseline Anxiety0.20.31.00.50.70.40.40.4-0.30.30.40.3-0.40.3-0.30.30.30.70.70.20.30.70.7-0.7-1.0
Tail length5.019.420.6-4.4-4.3-4.4-4.5-4.54.5-4.5-4.5-4.54.5-4.54.5-4.5-4.5-4.4-4.4-4.4-4.5-4.3-4.44.43.0
Length with tail8.537.241.4-6.4-6.1-6.3-6.4-6.36.3-6.3-6.3-6.36.3-6.36.3-6.3-6.3-6.0-6.0-6.2-6.2-5.9-6.06.01.8
Length without tail6.621.325.6-5.1-4.6-4.9-4.9-4.84.8-4.8-4.8-4.84.8-4.84.8-4.8-4.8-4.4-4.4-5.0-4.6-4.4-4.44.4-0.3
Times rat made contact with spout0.50.60.8-0.9-0.9-0.8-0.8-0.80.8-0.7-0.8-0.80.8-0.70.7-0.7-0.7-0.9-0.9-0.6-0.8-0.9-0.90.9-0.0
Lifetime Intake2.12.53.01.71.61.71.71.7-1.71.71.71.7-1.71.7-1.71.71.71.51.51.61.61.41.4-1.40.3
Liver weight, left0.61.11.2-1.0-1.0-1.1-1.1-1.11.1-1.1-1.1-1.11.1-1.11.1-1.1-1.1-0.8-0.8-0.9-1.1-1.1-1.11.10.1
Liver weight, right1.72.94.4-1.6-1.7-1.7-1.7-1.71.7-1.7-1.7-1.71.7-1.71.7-1.7-1.7-1.7-1.7-1.7-1.7-1.8-1.81.82.1
Locomotor activity5.78.910.3-2.9-3.0-3.0-3.0-3.03.0-3.0-3.0-3.03.0-3.03.0-3.0-3.0-3.1-3.1-3.2-3.0-3.0-3.03.02.2
Locomotor testing distance4.27.59.5-2.7-2.7-2.7-2.8-2.82.8-2.8-2.8-2.82.8-2.82.8-2.8-2.8-2.7-2.7-3.1-2.8-2.7-2.62.61.7
Locomotor testing rearing0.00.10.5-0.0-0.0-0.1-0.3-0.30.3-0.3-0.3-0.30.3-0.40.4-0.4-0.4-0.0-0.0-0.7-0.5-0.3-0.30.3-0.1
Locomotion in novel chamber0.20.32.70.20.30.30.40.4-0.40.40.40.4-0.40.4-0.40.40.40.20.20.40.50.40.4-0.4-1.6
Locomotion in novel chamber post-restriction0.30.50.8-0.9-0.6-0.8-0.8-0.80.8-0.8-0.8-0.80.8-0.80.8-0.8-0.8-0.6-0.6-0.8-0.8-0.5-0.50.5-0.5
Fecal boli incidents, locomotor time 10.30.40.7-0.6-0.6-0.7-0.6-0.60.7-0.6-0.7-0.70.7-0.70.7-0.7-0.7-0.8-0.8-0.7-0.7-0.8-0.60.6-0.2
Change in fecal boli incidents, locomotor task0.00.00.40.10.10.00.10.1-0.10.10.10.1-0.10.1-0.10.10.10.30.30.00.10.20.2-0.2-0.6
Time >=10cm from walls, locomotor time 10.20.20.40.20.60.50.40.4-0.30.30.40.3-0.40.3-0.30.30.30.60.60.30.40.70.6-0.60.2
Bouts of movement, locomotor time 10.10.11.2-0.1-0.3-0.4-0.2-0.20.2-0.2-0.2-0.20.2-0.20.2-0.2-0.2-0.2-0.2-0.2-0.2-0.4-0.20.21.1
Total resting periods, locomotor time 10.00.10.6-0.1-0.2-0.3-0.1-0.10.1-0.1-0.1-0.20.1-0.10.2-0.2-0.2-0.1-0.1-0.1-0.2-0.2-0.10.10.8
Rest time, locomotor task time 10.60.81.70.81.00.70.80.8-0.80.80.80.8-0.80.8-0.80.80.81.01.00.90.81.01.0-1.0-1.3
Distance moved, locomotor task time 11.01.51.8-1.4-1.2-1.2-1.3-1.31.3-1.3-1.3-1.31.3-1.31.3-1.3-1.3-1.3-1.3-1.3-1.2-1.1-1.21.2-0.3
Vertical activity count, locomotor time 10.41.01.1-1.1-1.1-1.0-1.0-1.01.0-1.0-1.0-1.01.0-1.01.0-1.0-1.0-1.0-1.0-1.0-0.9-0.9-1.01.00.6
Time >=10cm from walls, locomotor time 20.91.41.8-1.3-1.0-1.1-1.2-1.21.2-1.2-1.2-1.21.2-1.21.2-1.2-1.2-1.0-1.0-1.2-1.2-1.0-1.11.1-0.9
Bouts of movement, locomotor time 20.00.00.10.20.10.10.10.1-0.00.00.10.0-0.10.0-0.00.00.00.10.1-0.10.00.00.0-0.0-0.4
Total resting periods, locomotor time 20.10.10.20.40.40.30.30.3-0.30.30.30.3-0.30.3-0.30.30.30.30.30.10.30.30.3-0.3-0.4
Rest time, locomotor task time 20.00.10.10.30.20.20.20.2-0.20.20.20.2-0.20.2-0.20.20.20.30.30.10.20.30.3-0.30.2
Distance moved, locomotor task time 20.91.11.6-1.3-1.0-1.0-1.1-1.11.1-1.1-1.1-1.11.1-1.11.1-1.1-1.1-1.0-1.0-1.0-1.0-1.0-0.90.9-0.4
Vertical activity count, locomotor time 20.00.00.1-0.3-0.2-0.1-0.2-0.20.2-0.2-0.2-0.20.2-0.20.2-0.2-0.2-0.2-0.2-0.1-0.2-0.2-0.10.10.1
Light reinforcement 10.51.11.5-1.1-1.1-1.1-1.1-1.11.0-1.0-1.1-1.01.1-1.01.0-1.0-1.0-1.2-1.2-0.9-1.0-1.1-1.01.01.0
Light reinforcement 20.10.10.50.20.20.20.20.3-0.30.30.30.3-0.30.3-0.30.30.30.40.40.40.40.40.5-0.50.7
Bone: marrow area0.10.11.1-0.1-0.2-0.2-0.3-0.30.3-0.3-0.3-0.30.3-0.30.3-0.3-0.3-0.3-0.3-0.5-0.3-0.2-0.20.21.0
Bone: maximum diameter0.40.70.90.80.80.90.90.9-0.90.90.90.9-0.90.9-0.90.90.90.60.60.80.90.80.8-0.8-0.7
Bone: maximum force0.61.11.3-1.1-1.1-1.1-1.1-1.11.1-1.1-1.1-1.11.1-1.11.1-1.1-1.1-1.1-1.1-1.1-1.0-1.1-1.11.10.3
Bone: maximum moment0.71.21.5-1.1-1.2-1.2-1.1-1.11.1-1.1-1.1-1.11.1-1.11.1-1.1-1.1-1.2-1.2-1.2-1.1-1.1-1.11.10.3
Mean time between licks in bursts0.82.02.11.41.41.41.41.4-1.41.41.41.4-1.41.4-1.41.41.41.41.41.11.51.41.4-1.4-1.1
Mean num. licks in bursts0.71.01.4-1.2-1.2-1.1-1.0-1.01.0-1.0-1.0-1.01.0-1.01.0-1.0-0.9-1.1-1.1-0.8-0.9-1.0-1.01.01.2
Cd content in liver0.10.10.20.20.20.30.30.3-0.30.30.30.3-0.30.3-0.30.40.30.10.10.30.40.30.3-0.30.4
Co content in liver1.21.42.11.41.41.31.31.2-1.21.21.21.2-1.21.2-1.21.21.20.90.91.01.11.21.2-1.2-0.5
Cu content in liver4.04.75.8-2.2-2.1-2.2-2.2-2.22.2-2.2-2.2-2.22.2-2.22.2-2.2-2.2-2.4-2.4-2.1-2.1-2.1-2.12.11.6
Fe content in liver1.21.41.9-1.0-1.0-1.0-1.1-1.21.2-1.2-1.2-1.21.2-1.21.2-1.2-1.2-1.4-1.4-1.3-1.4-1.3-1.31.30.3
K content in liver0.40.33.1-0.5-0.6-0.5-0.4-0.40.4-0.4-0.4-0.40.4-0.40.4-0.4-0.3-0.9-0.9-0.3-0.2-0.3-0.30.31.8
Mg content in liver1.11.13.00.80.80.80.91.1-1.11.11.11.1-1.11.1-1.11.11.10.20.21.01.31.21.2-1.21.7
Mn content in liver0.30.36.5-0.3-0.4-0.3-0.2-0.10.1-0.1-0.1-0.10.1-0.10.1-0.1-0.0-0.6-0.6-0.10.20.10.1-0.12.5
Na content in liver0.70.82.2-0.6-0.6-0.7-0.7-0.80.8-0.8-0.8-0.80.8-0.80.8-0.8-0.8-1.2-1.2-0.7-0.9-0.9-0.90.91.5
Rb content in liver0.60.71.5-0.4-0.3-0.5-0.7-0.80.8-0.9-0.8-0.80.8-0.90.9-0.9-0.9-0.6-0.6-1.2-1.1-1.1-1.01.0-0.5
Se content in liver0.10.10.3-0.4-0.4-0.4-0.3-0.20.2-0.2-0.2-0.20.2-0.20.2-0.2-0.2-0.5-0.50.1-0.1-0.1-0.10.10.5
Sr content in liver0.20.11.4-0.3-0.3-0.20.00.2-0.20.20.20.2-0.20.2-0.20.20.3-0.2-0.20.40.60.40.4-0.41.2
Zn content in liver2.12.43.6-1.6-1.6-1.6-1.5-1.51.5-1.5-1.5-1.51.5-1.51.5-1.5-1.4-1.9-1.9-1.5-1.4-1.4-1.41.41.9
Bone: minimum diameter0.61.01.31.11.11.01.01.0-1.01.01.01.0-1.01.0-1.01.01.01.01.00.81.01.11.1-1.1-0.5
Time in familiar zone, hab. session 11.51.42.41.51.61.41.21.2-1.11.11.21.1-1.21.1-1.11.11.11.31.30.90.91.21.2-1.2-1.2
Time in novel zone, hab. session 10.70.71.1-1.0-1.1-1.0-0.9-0.90.8-0.8-0.9-0.80.9-0.80.8-0.8-0.8-1.0-1.0-0.6-0.7-0.9-0.80.80.6
Total zone transitions, hab. session 10.70.92.9-1.1-1.2-1.1-1.0-0.90.9-0.9-0.9-0.90.9-0.80.8-0.8-0.8-1.1-1.1-0.8-0.7-0.8-0.80.81.7
Total locomotion distance, hab. session 10.30.40.7-0.8-0.8-0.8-0.7-0.70.6-0.6-0.6-0.60.6-0.60.6-0.6-0.6-0.7-0.7-0.5-0.5-0.6-0.60.60.7
Locomotion velocity, hab. session 10.40.50.8-0.9-0.9-0.8-0.7-0.70.7-0.7-0.7-0.70.7-0.70.7-0.7-0.6-0.7-0.7-0.5-0.5-0.7-0.70.70.9
Time in familiar zone, hab. session 20.70.71.11.01.00.90.90.9-0.90.90.90.9-0.90.9-0.90.90.80.70.70.60.80.90.8-0.8-1.0
Time in novel zone, hab. session 20.10.10.2-0.2-0.2-0.1-0.2-0.20.2-0.2-0.2-0.20.2-0.20.2-0.2-0.2-0.1-0.1-0.3-0.3-0.3-0.20.20.5
Total zone transitions, hab. session 20.10.10.6-0.6-0.6-0.5-0.3-0.20.2-0.2-0.2-0.20.2-0.20.2-0.2-0.1-0.4-0.4-0.20.0-0.2-0.10.10.8
Total locomotion distance, hab. session 20.30.50.8-0.9-0.9-0.8-0.7-0.70.6-0.6-0.7-0.60.6-0.60.6-0.6-0.6-0.7-0.7-0.5-0.5-0.7-0.60.60.7
Locomotion velocity, hab. session 20.30.40.8-0.8-0.9-0.7-0.6-0.60.6-0.5-0.6-0.50.6-0.50.5-0.5-0.5-0.7-0.7-0.3-0.4-0.6-0.50.50.8
Novel to familiar place preference ratio1.01.17.5-0.8-0.9-0.8-0.9-0.90.9-0.9-0.9-0.90.9-0.90.9-0.9-0.9-0.9-0.9-1.1-0.9-0.8-0.80.82.7
Novelty place preference1.01.18.1-0.8-0.9-0.8-0.9-0.90.9-0.9-0.9-0.90.9-0.90.9-0.9-0.9-0.9-0.9-1.1-0.9-0.8-0.80.82.8
Time in novel zone, NPP test1.21.37.5-0.9-1.0-0.9-1.0-1.01.0-1.0-1.0-1.01.0-1.01.0-1.0-1.0-1.0-1.0-1.2-1.1-0.9-1.01.02.7
Total zone transitions, NPP test2.53.66.1-2.3-2.4-2.2-1.9-1.81.8-1.7-1.8-1.81.8-1.71.7-1.7-1.7-2.1-2.1-1.6-1.4-1.8-1.71.72.5
Total locomotion distance, NPP test1.11.62.4-1.5-1.6-1.4-1.3-1.21.2-1.2-1.2-1.21.2-1.21.2-1.2-1.2-1.4-1.4-1.0-1.0-1.2-1.21.21.1
Locomotion velocity, NPP test1.21.72.8-1.6-1.7-1.5-1.4-1.31.3-1.3-1.3-1.31.3-1.21.2-1.2-1.2-1.5-1.5-1.0-1.0-1.3-1.31.31.4
Intraocular pressure0.91.31.9-0.9-0.8-0.9-1.1-1.21.2-1.2-1.2-1.21.2-1.21.2-1.2-1.3-1.0-1.0-1.3-1.4-1.3-1.21.2-0.3
Delta distance traveled before/after self-admin0.10.11.1-0.2-0.5-0.3-0.2-0.20.2-0.2-0.2-0.20.2-0.20.2-0.2-0.2-0.4-0.4-0.3-0.2-0.3-0.30.31.1
Delta ambulatory time before/after self-admin1.01.34.0-0.9-1.3-1.1-1.1-1.01.1-1.1-1.0-1.11.0-1.11.1-1.1-1.0-1.1-1.1-1.2-1.0-1.0-1.01.02.0
Parametrial fat weight0.81.82.7-1.6-1.5-1.5-1.5-1.41.4-1.4-1.4-1.41.4-1.41.4-1.4-1.4-1.4-1.4-1.3-1.2-1.2-1.21.20.5
Pavlov. Cond. lever latency4.45.56.1-2.2-2.3-2.3-2.3-2.42.4-2.4-2.4-2.42.4-2.42.4-2.4-2.4-2.4-2.4-2.4-2.5-2.5-2.42.41.6
Pavlov. Cond. magazine entry latency7.79.910.43.13.23.23.23.2-3.23.23.23.2-3.23.2-3.23.23.23.13.13.13.23.23.2-3.2-2.0
Pavlov. Cond. change in total contacts1.71.82.21.41.51.41.41.4-1.41.41.41.4-1.41.3-1.31.31.31.31.31.21.31.31.3-1.3-1.2
Pavlov. Cond. index score6.58.38.62.82.92.92.92.9-2.92.92.92.9-2.92.9-2.92.92.92.92.92.82.92.92.9-2.9-2.2
Pavlov. Cond. latency score6.38.08.52.82.82.82.92.9-2.92.92.92.9-2.92.9-2.92.92.92.82.82.82.92.92.9-2.9-1.9
Pavlov. Cond. lever contacts2.53.03.61.61.61.61.71.8-1.81.81.81.8-1.81.8-1.81.81.81.81.81.81.91.81.8-1.8-1.3
Pavlov. Cond. magazine entry number7.89.910.3-3.2-3.2-3.2-3.2-3.23.2-3.2-3.2-3.23.2-3.23.2-3.2-3.2-3.1-3.1-3.0-3.2-3.2-3.23.22.3
Pavlov. Cond. intertrial magazine entries0.40.50.6-0.5-0.5-0.6-0.7-0.70.7-0.7-0.7-0.70.7-0.70.7-0.7-0.7-0.7-0.7-0.7-0.8-0.6-0.60.60.7
Pavlov. Cond. lever-magazine prob. diff.5.97.37.62.62.72.72.72.7-2.72.72.72.7-2.72.7-2.72.72.72.72.72.62.82.72.7-2.7-2.3
Pavlov. Cond. response bias7.08.79.22.92.92.93.03.0-3.03.03.03.0-3.03.0-3.03.03.02.92.92.93.03.03.0-3.0-2.4
Pavlov. Cond. lever latency0.50.71.01.01.01.01.00.9-0.90.90.90.9-0.90.9-0.90.90.90.80.81.00.80.80.6-0.6-0.4
Pavlov. Cond. magazine entry latency0.10.20.40.30.30.30.40.4-0.40.40.40.4-0.40.4-0.40.40.50.30.30.30.60.50.6-0.6-0.1
Pavlov. Cond. change in total contacts2.03.34.4-1.9-1.9-1.9-1.9-1.91.9-1.9-1.9-1.91.9-1.91.8-1.8-1.8-2.0-2.0-2.1-1.7-1.8-1.61.60.6
Pavlov. Cond. index score0.10.20.4-0.5-0.5-0.5-0.5-0.40.5-0.5-0.4-0.40.4-0.40.4-0.4-0.4-0.5-0.5-0.6-0.3-0.3-0.20.20.1
Pavlov. Cond. latency score0.10.10.2-0.4-0.4-0.4-0.4-0.30.3-0.3-0.3-0.30.3-0.30.3-0.3-0.3-0.4-0.4-0.4-0.1-0.20.0-0.00.1
Pavlov. Cond. lever contacts0.81.11.5-1.1-1.2-1.2-1.1-1.11.1-1.1-1.1-1.11.1-1.11.1-1.1-1.1-1.0-1.0-1.2-1.0-1.0-0.90.90.7
Pavlov. Cond. magazine entry number0.20.30.5-0.4-0.4-0.5-0.5-0.50.5-0.5-0.5-0.50.5-0.50.5-0.5-0.6-0.4-0.4-0.3-0.6-0.6-0.70.70.2
Pavlov. Cond. intertrial magazine entries0.50.81.21.11.11.01.00.9-0.90.90.90.9-0.90.9-0.90.90.81.01.00.80.70.70.6-0.6-0.4
Pavlov. Cond. lever-magazine prob. diff.0.10.10.3-0.5-0.5-0.5-0.4-0.40.4-0.4-0.4-0.40.4-0.30.3-0.3-0.3-0.4-0.4-0.5-0.2-0.2-0.10.10.1
Pavlov. Cond. response bias0.00.10.2-0.3-0.3-0.3-0.3-0.30.3-0.3-0.3-0.30.3-0.30.3-0.3-0.2-0.2-0.2-0.4-0.1-0.20.0-0.0-0.0
Time in closed arm before self-admin0.70.91.1-1.0-0.9-0.9-1.0-1.01.0-1.0-1.0-1.01.0-1.01.0-1.0-1.0-1.0-1.0-1.0-1.0-1.1-1.11.1-0.2
Time in closed arm after self-admin0.40.43.50.30.70.50.50.5-0.50.50.50.5-0.50.5-0.50.50.50.60.60.50.50.60.6-0.6-1.9
Time in open arm before self-admin0.91.01.71.00.80.81.11.0-1.11.11.01.1-1.01.1-1.11.11.10.90.91.31.01.01.0-1.00.2
Time in open arm after self-admin0.40.44.60.50.30.50.40.4-0.40.40.40.4-0.40.4-0.40.40.40.40.40.50.40.50.5-0.52.1
Bone: periosteal estimation0.00.00.00.10.10.00.00.0-0.00.00.00.0-0.0-0.0-0.00.0-0.0-0.1-0.1-0.2-0.00.10.1-0.10.1
Bone: periosteal perimeter1.01.71.91.41.31.41.41.4-1.41.41.41.4-1.41.4-1.41.41.41.21.21.21.31.31.3-1.3-0.5
Bone: post-yield work0.00.00.0-0.1-0.1-0.1-0.1-0.10.1-0.1-0.1-0.10.1-0.10.1-0.0-0.0-0.0-0.0-0.1-0.0-0.1-0.10.10.1
Progressive ratio test 1 active lever presses0.10.12.30.20.00.10.10.1-0.10.10.10.1-0.10.1-0.10.10.10.00.00.10.1-0.1-0.10.11.5
Progressive ratio test 1 breakpoint0.10.12.20.20.00.20.20.1-0.10.20.10.1-0.10.1-0.10.10.10.00.00.10.1-0.0-0.00.01.5
Progressive ratio test 1 inactive lever presses0.40.50.70.80.70.70.80.7-0.80.80.70.8-0.70.7-0.80.80.70.70.70.70.70.50.5-0.5-0.9
Progressive ratio test 2 active lever presses2.02.43.21.61.41.61.71.6-1.71.71.61.7-1.61.7-1.71.71.71.31.31.81.61.31.3-1.3-0.0
Progressive ratio test 2 breakpoint2.12.43.21.61.41.61.71.7-1.71.71.61.7-1.71.7-1.71.71.71.31.31.81.61.31.3-1.3-0.1
Progressive ratio test 2 inactive lever presses2.23.64.22.01.71.92.02.0-2.02.02.02.0-2.02.0-2.02.02.01.71.72.12.01.51.5-1.5-1.6
Incentive Sensitization - Responses2.02.93.41.71.61.71.81.8-1.81.81.71.8-1.81.8-1.81.81.81.61.61.81.71.51.5-1.5-1.2
Incentive Sensitization - Breakpoint2.22.93.41.81.61.71.81.8-1.81.81.81.8-1.81.8-1.81.81.81.61.61.81.81.51.5-1.5-1.2
Sum of active levers in priming session hrs 5-60.10.11.6-0.1-0.3-0.1-0.1-0.10.1-0.0-0.1-0.10.1-0.10.1-0.1-0.1-0.3-0.30.1-0.1-0.3-0.30.31.2
Progressive ratio2.43.74.7-2.0-2.0-2.0-1.9-1.91.9-1.9-1.9-1.91.9-1.91.9-1.9-1.9-2.2-2.2-2.0-1.9-1.9-1.91.91.1
Food seeking constrained by brief footshock1.31.73.10.91.31.21.21.2-1.21.21.21.2-1.21.2-1.21.21.21.41.41.21.31.41.4-1.4-1.8
Seeking ratio, punishment vs. effort4.76.77.92.52.72.62.52.6-2.62.62.62.6-2.62.6-2.62.62.62.82.82.62.62.72.7-2.7-2.4
Retroperitoneal fat weight1.56.48.0-2.8-2.5-2.6-2.7-2.72.7-2.7-2.7-2.72.7-2.72.7-2.7-2.7-2.4-2.4-2.6-2.5-2.3-2.32.30.4
Reaction time number correct0.40.71.30.91.21.00.80.8-0.80.80.80.8-0.80.8-0.80.80.80.90.90.40.71.01.0-1.0-1.0
Reaction time mean minus median0.00.10.7-0.4-0.5-0.3-0.3-0.30.3-0.3-0.3-0.30.3-0.30.3-0.3-0.3-0.4-0.4-0.1-0.2-0.3-0.30.30.8
Reaction time mean minus median AUC0.10.41.4-0.6-0.7-0.6-0.6-0.60.6-0.6-0.5-0.60.5-0.60.6-0.6-0.5-0.6-0.6-0.5-0.5-0.5-0.60.61.2
Reaction time num false alarms0.20.30.50.70.60.70.60.6-0.60.60.60.6-0.60.6-0.60.60.60.50.50.50.50.40.5-0.50.4
Reaction time num false alarms AUC0.10.10.90.40.30.40.30.3-0.30.30.30.3-0.30.3-0.30.30.20.20.20.20.20.10.2-0.20.9
Reaction time trials correct on left0.40.71.30.91.21.00.80.8-0.80.80.80.8-0.80.8-0.80.80.80.90.90.40.71.01.0-1.0-1.0
Reaction time trials on left0.40.81.40.91.21.00.80.8-0.80.80.80.8-0.80.8-0.80.80.80.90.90.50.71.01.0-1.0-1.0
Reaction time mean0.00.00.5-0.00.10.1-0.0-0.10.1-0.1-0.1-0.10.1-0.10.1-0.1-0.1-0.1-0.1-0.0-0.1-0.0-0.00.00.7
Reaction time mean AUC0.00.00.60.00.20.20.00.0-0.0-0.00.00.0-0.0-0.00.0-0.0-0.0-0.0-0.00.1-0.10.10.0-0.00.8
Median of all reaction times0.00.00.30.20.40.30.10.1-0.10.10.10.1-0.10.1-0.10.10.10.10.10.1-0.00.10.1-0.10.6
Reaction time omissions0.10.10.20.40.40.50.40.3-0.30.30.30.3-0.30.3-0.30.30.20.30.30.40.10.10.1-0.10.0
Reaction time false alarm rate0.00.11.00.1-0.10.10.10.1-0.10.10.10.1-0.10.0-0.00.00.0-0.1-0.10.2-0.0-0.2-0.10.11.0
Reaction time premature initiation rate2.53.54.5-1.8-2.1-1.9-1.9-1.91.9-1.9-1.9-1.91.9-1.91.9-1.9-1.9-2.0-2.0-1.6-1.8-2.1-2.12.10.9
Reaction time premature initiations0.91.72.1-1.3-1.4-1.3-1.3-1.31.3-1.3-1.3-1.31.3-1.31.3-1.3-1.3-1.4-1.4-1.2-1.3-1.4-1.41.40.3
Std. dev. reaction times0.10.21.7-0.4-0.4-0.3-0.4-0.40.4-0.4-0.4-0.40.4-0.40.4-0.4-0.4-0.5-0.5-0.2-0.4-0.4-0.40.41.3
Reaction time trials completed0.40.81.40.91.21.00.80.8-0.80.80.80.8-0.80.8-0.80.80.80.90.90.50.71.01.0-1.0-1.0
Reaction time trials AUC0.51.01.71.01.31.11.00.9-0.90.90.90.9-0.90.9-0.90.90.91.11.10.60.91.21.1-1.1-1.1
Run reversals in cocaine runway, females1.61.64.30.91.41.11.11.1-1.11.01.11.1-1.11.1-1.01.01.11.51.51.21.11.61.6-1.6-2.1
Run reversals in cocaine runway, males1.21.21.6-1.1-1.2-1.0-1.1-1.11.0-1.0-1.1-1.01.1-1.01.0-1.0-1.0-1.2-1.2-1.1-1.0-1.3-1.31.30.3
Latency to leave start box in cocaine runway0.30.30.5-0.6-0.6-0.6-0.6-0.60.5-0.5-0.6-0.50.5-0.50.5-0.5-0.5-0.7-0.7-0.7-0.5-0.6-0.60.6-0.5
Latency to leave start box in cocaine runway, F0.70.91.3-1.0-0.9-0.9-1.0-0.90.9-0.9-0.9-0.90.9-0.90.9-0.9-0.9-1.0-1.0-1.1-0.9-0.9-0.90.9-0.4
Latency to leave start box in cocaine runway, M0.60.61.10.80.60.70.80.8-0.80.80.80.8-0.80.8-0.80.80.80.50.51.10.80.60.6-0.6-0.5
Std. dev. time between licks in bursts4.46.06.92.62.62.52.42.5-2.42.42.52.4-2.52.4-2.42.42.42.62.62.02.42.52.6-2.6-2.0
Total sessions with >9 infusions0.60.71.50.80.90.90.90.9-0.90.90.80.9-0.90.9-0.90.90.90.80.80.90.80.70.7-0.7-1.2
Short access day 1 total inactive lever presses4.45.87.92.42.72.42.32.3-2.32.32.32.3-2.32.3-2.32.32.32.62.62.22.32.52.5-2.5-2.8
Short access day 10 total inactive lever presses0.10.20.6-0.3-0.4-0.5-0.3-0.30.3-0.3-0.3-0.30.3-0.30.3-0.3-0.3-0.5-0.5-0.3-0.3-0.5-0.50.5-0.7
Short access day 1 total infusions2.93.94.52.12.12.12.02.0-2.02.02.02.0-2.02.0-2.02.02.02.02.02.02.01.91.9-1.9-1.0
Short access day 10 total infusions2.32.93.21.81.71.81.81.8-1.81.81.81.8-1.81.8-1.81.81.81.81.81.71.71.61.6-1.6-0.1
Short access total infusions3.54.45.22.12.32.22.22.2-2.12.12.22.1-2.12.1-2.12.12.12.22.22.12.12.12.1-2.1-0.6
Short access day 1 locomotion0.60.82.30.80.70.80.90.9-0.90.90.90.9-0.90.9-0.90.90.90.70.70.90.90.70.7-0.7-1.5
Short access day 10 total locomotion0.00.11.7-0.2-0.1-0.1-0.1-0.10.1-0.1-0.1-0.10.1-0.10.1-0.1-0.1-0.0-0.0-0.1-0.1-0.1-0.10.11.3
Short access total locomotion0.10.10.40.20.10.20.20.2-0.30.30.20.3-0.20.3-0.30.30.30.10.10.30.30.00.0-0.00.6
One hour access (0.3 mA shock)0.80.91.11.01.01.01.01.0-0.90.91.00.9-0.90.9-0.90.90.91.01.00.90.90.90.9-0.91.1
Compulsive drug intake0.91.12.20.91.20.90.90.9-0.90.90.90.9-0.90.9-0.90.90.91.31.30.70.91.51.5-1.5-0.5
One hour access (shock baseline)0.30.50.70.80.40.80.80.8-0.80.80.70.8-0.80.8-0.80.80.80.40.40.90.70.20.2-0.20.8
Social response proportion0.30.30.5-0.6-0.4-0.5-0.5-0.60.6-0.6-0.6-0.60.6-0.60.6-0.6-0.6-0.4-0.4-0.5-0.7-0.7-0.70.7-0.5
Social responses0.40.61.2-0.6-0.9-0.7-0.7-0.70.7-0.7-0.7-0.70.7-0.70.7-0.7-0.7-0.8-0.8-0.6-0.7-0.8-0.90.91.1
Social time0.40.50.60.70.70.60.70.7-0.70.70.70.7-0.70.7-0.70.70.70.70.70.80.70.80.8-0.8-0.4
Soleus weight3.911.512.9-3.6-3.6-3.6-3.5-3.53.5-3.5-3.5-3.53.5-3.43.4-3.4-3.4-3.4-3.4-3.6-3.3-3.3-3.33.31.8
Bone: stiffness0.20.30.4-0.5-0.5-0.5-0.5-0.50.5-0.5-0.5-0.50.5-0.50.5-0.5-0.5-0.6-0.6-0.5-0.5-0.5-0.50.50.5
Tibialis anterior weight0.00.11.4-0.2-0.2-0.2-0.2-0.10.1-0.1-0.1-0.10.1-0.10.1-0.1-0.10.00.0-0.2-0.1-0.1-0.10.1-1.2
Time to tail flick, vehicle, before self-admin1.61.72.0-1.3-1.1-1.3-1.3-1.41.4-1.4-1.4-1.41.4-1.41.4-1.4-1.4-1.2-1.2-1.4-1.4-1.3-1.31.30.0
Time to tail flick, vehicle, after self-admin0.30.40.8-0.5-0.8-0.5-0.6-0.50.5-0.5-0.5-0.50.5-0.50.5-0.5-0.5-0.9-0.9-0.6-0.5-0.9-0.90.90.2
Time to tail flick, test, before self-admin0.10.11.9-0.2-0.3-0.1-0.1-0.10.0-0.0-0.1-0.00.0-0.00.0-0.0-0.0-0.3-0.30.10.0-0.1-0.10.11.4
Time to tail flick, test, after self-admin0.10.10.30.40.30.40.40.4-0.40.40.40.4-0.40.4-0.40.40.40.30.30.60.40.20.2-0.2-0.3
Delta time to tail flick, vehicle, before/after SA0.30.30.50.70.30.60.60.6-0.70.70.60.7-0.60.7-0.70.70.70.20.20.60.70.30.3-0.30.1
Delta time to tail flick, test, before/after SA0.20.30.40.70.60.50.50.5-0.50.50.50.5-0.50.5-0.50.50.50.50.50.50.40.40.4-0.4-0.7
Tibia length6.317.321.8-4.6-4.7-4.6-4.4-4.24.2-4.2-4.2-4.24.2-4.24.2-4.2-4.1-4.3-4.3-4.0-3.8-4.1-4.14.12.0
Ambulatory time before self-admin0.81.34.91.11.21.11.01.0-1.01.01.01.0-1.01.0-1.01.01.01.21.20.80.91.11.1-1.1-2.2
Ambulatory time after self-admin0.00.00.20.30.10.10.10.1-0.10.10.20.1-0.10.1-0.10.10.10.20.2-0.20.10.30.3-0.3-0.4
Bone: tissue strength2.92.93.6-1.7-1.6-1.8-1.8-1.81.8-1.8-1.8-1.81.8-1.81.8-1.8-1.8-1.7-1.7-1.9-1.8-1.6-1.61.6-0.1
Total heroin consumption1.72.02.5-1.3-1.6-1.5-1.5-1.41.5-1.5-1.4-1.51.5-1.51.5-1.5-1.5-1.5-1.5-1.5-1.5-1.3-1.31.30.7
Bone: trabecular number0.61.01.91.01.01.01.01.0-1.01.01.01.0-1.01.0-1.01.01.01.41.41.01.01.11.0-1.0-0.4
Bone: trabecular spacing1.52.02.9-1.4-1.4-1.5-1.4-1.41.4-1.4-1.4-1.41.4-1.51.5-1.5-1.4-1.7-1.7-1.4-1.4-1.4-1.41.40.4
Bone: trabecular thickness0.00.10.4-0.4-0.4-0.3-0.2-0.20.2-0.2-0.2-0.20.2-0.20.2-0.2-0.2-0.0-0.0-0.1-0.1-0.1-0.20.20.6
Bone: trabecular tissue density0.40.60.8-0.9-0.9-0.9-0.8-0.80.8-0.7-0.8-0.80.8-0.70.7-0.7-0.7-0.9-0.9-0.6-0.7-0.9-0.90.90.9
Water consumed over 24 hours0.10.10.8-0.3-0.2-0.2-0.2-0.20.1-0.1-0.2-0.10.2-0.10.1-0.1-0.1-0.3-0.3-0.0-0.1-0.2-0.20.2-0.9
Number of responses in last shaping day0.20.30.50.70.40.50.60.6-0.60.60.60.6-0.60.5-0.60.60.50.40.40.50.50.30.3-0.3-0.4