Hub : Genes

Polr3f

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 OFC gene expression Polr3f 0.23 0.16 4.6e-03 0.12 0.09 0.13 0.12 7.5e-04 3.4e-03 6.2e-04 1.2e-03
2 PL gene expression Polr3f 0.11 0.07 3.9e-07 0.06 0.06 0.06 0.04 5.0e-07 2.8e-07 1.5e-07 6.8e-05
3 NAcc gene expression Polr3f 0.02 0.01 9.2e-04 0.01 0.01 0.01 0 6.9e-03 6.7e-03 4.2e-03 6.1e-02
4 Liver mRNA stability Polr3f 0.29 0.11 0.0e+00 0.23 0.23 0.23 0.23 3.6e-25 4.1e-25 9.1e-25 5.5e-25
5 Liver alternative TSS NM_001107784.1 0.04 0.03 2.3e-03 0.02 0.02 0.01 0.02 1.1e-03 4.7e-03 8.7e-03 1.3e-03
6 Liver alternative TSS XM_039105045.2 0.03 0.03 2.5e-03 0.02 0.01 0.01 0.02 1.1e-03 7.0e-03 8.8e-03 1.9e-03
7 Liver gene expression Polr3f 0.3 0.1 0.0e+00 0.2 0.23 0.24 0.23 3.8e-22 1.0e-25 6.5e-26 1.0e-25
8 Adipose gene expression Polr3f 0.1 0.05 2.6e-11 0.04 0.06 0.05 0.05 4.8e-05 2.3e-07 1.4e-06 1.1e-06
9 BLA mRNA stability Polr3f 0.28 0.1 1.2e-14 0.24 0.28 0.24 0.25 4.6e-13 6.3e-15 3.0e-13 1.8e-13
10 PL mRNA stability Polr3f 0.25 0.09 0.0e+00 0.24 0.3 0.29 0.28 4.7e-26 1.5e-32 1.0e-31 9.6e-31
11 Adipose mRNA stability Polr3f 0.42 0.14 0.0e+00 0.24 0.23 0.23 0.23 5.0e-26 2.5e-25 4.0e-25 1.1e-24
12 RMTg mRNA stability Polr3f 0.2 0.12 4.4e-03 0.02 -0.01 -0.01 -0 1.2e-01 8.6e-01 8.1e-01 4.4e-01
13 pVTA mRNA stability Polr3f 0.17 0.08 1.9e-10 0.16 0.14 0.15 0.15 1.1e-12 5.6e-11 6.2e-12 3.5e-12
14 pVTA gene expression Polr3f 0.16 0.08 1.3e-07 0.06 0.09 0.07 0.08 6.4e-06 1.5e-07 1.2e-06 9.1e-07
15 IC mRNA stability Polr3f 0.52 0.13 6.4e-14 0.33 0.32 0.34 0.36 2.6e-14 2.8e-14 4.7e-15 1.1e-15
16 Adipose alternative TSS NM_001107784.1 0.03 0.02 1.6e-03 0.03 0.02 0.02 0.03 2.2e-04 6.5e-03 1.3e-03 6.4e-04
17 Adipose alternative TSS XM_039105045.2 0.03 0.02 1.7e-03 0.03 0.02 0.03 0.03 2.5e-04 5.3e-03 8.4e-04 6.5e-04
18 LHb mRNA stability Polr3f 0.4 0.23 1.4e-03 0.08 0.04 0.02 0.02 6.1e-03 3.7e-02 1.3e-01 1.0e-01
19 OFC mRNA stability Polr3f 0.55 0.16 2.6e-07 0.27 0.15 0.24 0.21 4.4e-07 2.5e-04 1.9e-06 1.2e-05
20 IL mRNA stability Polr3f 0.42 0.14 4.5e-08 0.25 0.26 0.25 0.27 8.5e-07 5.3e-07 9.0e-07 3.4e-07
21 NAcc mRNA stability Polr3f 0.24 0.09 0.0e+00 0.19 0.2 0.22 0.22 1.5e-27 6.2e-30 7.7e-32 5.0e-33
22 Brain mRNA stability Polr3f 0.29 0.11 0.0e+00 0.23 0.28 0.3 0.29 1.3e-21 1.8e-26 2.2e-28 1.4e-27

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22
Bone: apparent density0.00.00.1-0.2-0.0-0.1-0.00.1-0.1-0.00.10.30.10.0-0.2-0.00.2-0.10.2-0.2-0.2-0.2-0.2-0.1-0.2
Area under the delay curve1.51.84.2-0.7-1.2-1.60.30.5-0.50.41.11.91.71.51.61.52.01.6-1.41.41.41.41.21.31.1
BMI with tail3.311.340.26.35.95.76.1-5.75.74.53.40.30.8-0.5-0.4-0.20.1-0.40.0-0.0-0.0-0.01.10.81.8
BMI without tail2.88.631.95.75.44.85.5-4.84.83.82.80.00.4-1.1-0.8-0.7-0.2-0.90.6-0.6-0.6-0.60.50.01.1
Body weight3.816.761.77.97.67.37.3-6.66.64.62.7-0.9-0.5-1.8-1.7-1.6-1.0-1.81.6-1.6-1.6-1.6-0.3-0.40.9
Weight adjusted by age0.40.71.5-0.3-0.0-0.1-0.30.6-0.6-0.8-0.9-0.7-0.8-0.9-1.1-1.1-0.6-1.00.9-0.9-0.9-0.9-1.2-1.1-0.8
Bone surface0.10.20.70.80.90.80.5-0.70.70.40.2-0.4-0.3-0.2-0.5-0.1-0.4-0.20.5-0.5-0.5-0.5-0.1-0.1-0.4
Bone volume0.20.30.60.40.60.40.1-0.20.2-0.1-0.3-0.5-0.5-0.6-0.8-0.5-0.5-0.70.7-0.7-0.7-0.7-0.7-0.7-0.7
Breakpoint value in progressive ratio session0.20.20.60.60.80.30.4-0.60.60.30.3-0.4-0.4-0.3-0.4-0.4-0.7-0.40.4-0.4-0.4-0.40.1-0.1-0.2
Number of licking bursts0.10.10.60.30.3-0.10.5-0.40.40.50.50.80.60.10.10.10.6-0.1-0.10.10.10.10.0-0.10.4
Context. condit. distance diff. score0.30.40.90.10.40.5-0.0-0.10.1-0.1-0.2-0.4-0.5-1.0-0.8-0.6-0.6-0.80.8-0.8-0.8-0.8-0.8-0.9-0.5
Locomotion velocity, session 10.80.82.4-1.1-1.2-1.5-1.41.4-1.4-1.1-1.1-1.1-0.9-0.3-0.5-0.3-0.9-0.30.4-0.4-0.4-0.4-0.1-0.5-1.0
Locomotion distance, session 11.51.97.7-2.3-2.5-2.8-2.32.2-2.2-1.5-1.3-0.1-0.10.50.50.60.30.6-0.40.40.40.40.0-0.0-0.3
Locomotion velocity, session 22.02.45.3-1.6-2.1-2.3-1.21.2-1.2-0.30.00.91.02.01.81.61.31.8-1.81.81.81.81.61.50.8
Locomotion distance, session 22.43.38.4-2.7-2.5-2.7-2.92.9-2.9-2.5-2.4-1.3-1.4-0.6-0.8-0.9-1.0-0.70.8-0.8-0.8-0.8-1.2-1.2-1.8
Locomotion velocity, session 31.01.24.9-2.0-2.0-2.2-2.01.8-1.8-1.1-0.80.30.10.40.40.40.30.4-0.30.30.30.30.0-0.0-0.2
Locomotion distance, session 30.60.62.3-1.2-1.2-1.5-1.10.8-0.8-0.3-0.10.70.50.80.70.60.60.8-0.70.70.70.70.40.60.2
Stereotopy head waving bouts, day 30.10.10.3-0.0-0.10.0-0.20.2-0.2-0.4-0.4-0.6-0.4-0.3-0.2-0.3-0.5-0.30.3-0.3-0.3-0.3-0.2-0.3-0.4
Stereotopy head waving duration, day 30.10.20.40.30.30.30.1-0.10.1-0.3-0.3-0.7-0.5-0.5-0.4-0.5-0.6-0.50.5-0.5-0.5-0.5-0.3-0.4-0.4
Locomotion velocity, session 70.50.61.9-1.0-1.1-1.0-1.31.2-1.2-1.0-1.4-0.7-0.7-0.2-0.2-0.2-0.2-0.20.1-0.1-0.1-0.1-0.6-0.4-0.3
Locomotion distance, session 70.40.51.8-0.2-0.2-0.4-0.60.6-0.6-0.7-1.4-1.1-1.1-0.7-0.7-0.7-0.6-0.70.6-0.6-0.6-0.6-1.1-0.8-0.7
Stereotopy head waving bouts, day 70.20.30.50.40.20.10.5-0.60.60.50.50.40.50.60.60.40.50.5-0.60.60.60.60.60.70.4
Stereotopy head waving duration, day 70.10.10.3-0.4-0.4-0.5-0.20.2-0.20.00.20.30.30.50.50.20.20.4-0.40.40.40.40.50.50.1
Locomotion velocity, session 80.80.91.7-1.1-1.0-1.1-1.31.3-1.3-1.2-1.3-1.2-1.1-0.8-0.5-0.5-0.9-0.70.6-0.6-0.6-0.6-0.7-1.0-1.0
Locomotion distance, session 81.31.94.2-1.9-1.6-1.7-2.02.0-2.0-1.9-1.9-1.1-1.2-0.9-0.8-0.6-0.8-0.70.9-0.9-0.9-0.9-1.3-1.3-1.2
Degree of sensitization distance1.21.22.31.01.01.00.6-0.30.3-0.3-1.1-1.5-1.4-1.4-1.3-1.1-1.0-1.31.2-1.2-1.2-1.2-1.3-1.4-0.7
Degree of sensitization stereotypy0.20.20.60.70.70.40.7-0.80.80.70.60.30.30.30.2-0.10.10.2-0.20.20.20.20.40.50.1
Conditioned locomotion1.01.12.3-0.20.0-0.1-0.50.6-0.6-1.0-1.2-1.4-1.4-1.1-1.3-1.3-1.4-1.21.1-1.1-1.1-1.1-1.0-1.1-1.5
Cocaine response after cond. corrected1.01.32.8-1.2-1.0-1.0-1.61.4-1.4-1.5-1.7-0.8-0.9-1.1-0.7-0.7-0.5-0.81.0-1.0-1.0-1.0-1.5-1.2-0.8
Cocaine response after cond. not corrected1.51.83.8-1.7-1.5-1.4-1.91.8-1.8-1.8-1.9-0.8-1.0-1.1-0.8-0.8-0.5-0.91.0-1.0-1.0-1.0-1.7-1.4-1.1
Cocaine response before conditioning0.10.10.3-0.6-0.5-0.4-0.20.4-0.4-0.1-0.10.20.10.30.10.10.20.1-0.20.20.20.20.00.0-0.1
Saline control response3.64.88.01.01.31.20.10.2-0.2-1.3-2.0-2.8-2.7-2.6-2.5-2.6-2.6-2.72.6-2.6-2.6-2.6-2.5-2.6-2.4
Bone: connectivity density0.10.10.5-0.6-0.5-0.2-0.30.3-0.3-0.20.20.40.30.70.20.40.30.5-0.30.30.30.30.40.5-0.1
Bone: cortical apparent density0.60.91.9-0.8-0.9-0.2-0.20.1-0.10.30.91.21.21.31.21.41.11.2-0.90.90.90.91.01.01.0
Bone: cortical area0.30.40.90.50.20.60.9-0.60.60.80.80.60.70.60.60.80.70.6-0.60.60.60.60.50.50.9
Bone: cortical porosity0.20.30.70.50.30.20.8-0.50.50.50.80.40.50.40.30.20.20.3-0.50.50.50.50.80.40.5
Bone: cortical porosity0.20.21.10.70.60.61.0-0.70.70.50.70.10.30.10.10.0-0.0-0.0-0.20.20.20.20.50.10.3
Bone: cortical thickness1.42.23.60.2-0.30.21.1-0.80.81.41.91.71.91.81.81.81.61.7-1.61.61.61.61.91.71.7
Bone: cortical thickness1.01.21.9-0.9-1.3-1.1-0.20.5-0.50.00.51.21.21.41.21.31.41.3-1.21.21.21.21.01.10.8
Bone: cortical tissue density0.50.61.5-0.8-0.8-0.1-0.30.2-0.20.20.71.01.01.11.11.20.91.0-0.80.80.80.80.80.80.8
Condit. Reinf. active minus inactive responses0.20.20.5-0.10.2-0.0-0.10.1-0.1-0.0-0.20.0-0.2-0.4-0.6-0.6-0.2-0.50.7-0.7-0.7-0.7-0.6-0.5-0.3
Condit. Reinf. active-inactive response ratio0.10.20.4-0.10.1-0.1-0.10.2-0.2-0.1-0.20.1-0.2-0.5-0.6-0.5-0.1-0.40.6-0.6-0.6-0.6-0.6-0.4-0.2
Condit. Reinf. active responses0.10.10.2-0.2-0.1-0.3-0.30.2-0.2-0.0-0.20.1-0.1-0.1-0.3-0.3-0.0-0.20.4-0.4-0.4-0.4-0.3-0.2-0.2
Condit. Reinf. inactive responses0.00.00.10.0-0.2-0.1-0.10.1-0.1-0.0-0.2-0.3-0.10.30.20.1-0.00.1-0.10.10.10.10.20.1-0.1
Incentive salience index mean0.40.51.4-0.6-0.6-0.9-0.30.2-0.20.40.51.21.01.00.70.81.10.8-0.70.70.70.70.60.70.9
Condit. Reinf. lever presses2.23.05.4-0.4-0.8-1.00.2-0.30.31.21.52.32.22.31.92.02.32.0-2.02.02.02.01.91.92.2
Condit. Reinf. active minus inactive responses0.60.82.11.41.41.50.9-0.80.80.3-0.3-1.2-1.0-1.2-1.0-1.1-1.2-1.00.3-0.3-0.3-0.3-0.3-0.6-0.4
Condit. Reinf. active-inactive response ratio0.60.72.01.31.41.10.9-0.90.90.5-0.0-0.8-0.7-1.1-1.0-1.0-0.9-0.90.5-0.5-0.5-0.5-0.4-0.6-0.2
Condit. Reinf. active responses0.50.61.41.10.91.21.0-1.01.00.90.80.00.20.10.30.2-0.00.3-1.11.11.11.11.00.60.7
Condit. Reinf. inactive responses1.62.14.10.2-0.20.20.6-0.60.61.01.41.31.41.61.61.51.21.7-2.02.02.02.02.01.81.4
Condit. Reinf. lever presses1.21.66.32.42.52.31.8-1.81.81.20.6-0.9-0.8-0.9-1.1-1.2-1.2-0.90.3-0.3-0.3-0.30.1-0.1-0.5
Condit. Reinf. lever reinforcers received0.40.61.71.31.11.31.1-1.11.10.90.7-0.20.0-0.10.0-0.1-0.30.1-0.80.80.80.80.90.50.5
Conditioned reinforcement - actives2.13.66.8-0.8-0.6-0.6-1.51.5-1.5-2.4-2.6-2.5-2.5-1.8-1.8-2.0-2.1-1.81.8-1.8-1.8-1.8-2.2-2.0-2.5
Conditioned reinforcement - inactives3.55.18.6-1.2-0.7-0.4-2.11.9-1.9-2.8-2.9-2.7-2.8-2.3-2.3-2.3-2.5-2.22.3-2.3-2.3-2.3-2.6-2.5-2.7
Conditioned locomotion0.10.20.6-0.8-0.8-0.6-0.60.7-0.7-0.6-0.2-0.0-0.10.00.0-0.1-0.2-0.0-0.00.00.00.00.1-0.1-0.4
Patch foraging indifference point 0 sec1.63.05.6-0.40.10.4-1.40.9-0.9-1.6-2.4-2.3-2.3-2.0-1.9-2.1-2.1-2.01.5-1.5-1.5-1.5-2.2-2.1-2.0
Patch foraging indifference point AUC0.50.71.8-1.2-1.3-1.2-0.60.8-0.8-0.10.51.00.91.00.91.00.81.0-0.70.70.70.70.90.80.3
Delay disc. indifference point, 0s delay1.92.13.40.60.2-0.61.3-0.90.91.51.71.81.71.51.51.51.81.5-1.61.61.61.61.81.61.7
Delay disc. indifference point, 16s delay0.91.03.3-1.3-1.4-1.8-0.61.0-1.0-0.20.41.31.11.01.01.01.41.1-0.90.90.90.90.70.70.4
Delay disc. indifference point, 2s delay1.41.52.91.00.5-0.21.7-1.01.01.41.51.61.51.11.01.11.61.1-1.31.31.31.31.21.11.4
Delay disc. indifference point, 24s delay1.82.17.7-2.1-2.4-2.8-1.61.9-1.9-1.0-0.31.31.01.21.31.21.71.3-1.11.11.11.10.40.60.4
Delay disc. indifference point, 4s delay1.31.43.40.70.1-0.31.5-0.70.71.21.31.61.51.21.21.21.81.2-1.21.21.21.21.11.21.2
Delay disc. indifference point, 8s delay0.70.82.5-1.1-1.5-1.6-0.41.1-1.1-0.40.41.00.80.90.90.91.00.9-0.80.80.80.80.80.60.3
Indifference point function ln k0.40.81.80.00.10.3-0.40.4-0.4-0.8-1.3-1.4-1.3-1.2-1.1-1.0-1.0-1.10.7-0.7-0.7-0.7-1.2-1.1-0.8
Indifference point function log k0.40.81.80.00.10.3-0.40.4-0.4-0.8-1.3-1.4-1.3-1.2-1.1-1.0-1.0-1.10.7-0.7-0.7-0.7-1.2-1.1-0.8
Patch foraging total patch changes 0 sec1.63.05.4-0.7-0.10.1-1.61.1-1.1-1.7-2.3-2.2-2.2-1.9-1.9-2.0-2.1-2.01.5-1.5-1.5-1.5-2.1-2.0-2.1
Patch foraging total patch changes 12 sec0.00.00.20.40.20.40.4-0.20.20.1-0.1-0.3-0.20.20.10.0-0.00.1-0.10.10.10.10.10.2-0.2
Patch foraging total patch changes 18 sec0.91.42.7-1.4-1.0-0.6-1.71.4-1.4-1.6-1.5-1.0-1.2-0.7-1.0-0.9-1.0-0.81.2-1.2-1.2-1.2-1.2-1.0-1.4
Patch foraging total patch changes 24 sec0.20.30.5-0.2-0.1-0.1-0.50.3-0.3-0.4-0.5-0.4-0.5-0.5-0.7-0.7-0.5-0.60.7-0.7-0.7-0.7-0.7-0.5-0.7
Patch foraging total patch changes 6 sec0.50.71.5-0.5-0.00.0-0.90.5-0.5-0.7-1.1-0.8-0.9-1.0-1.0-1.1-0.8-1.00.8-0.8-0.8-0.8-1.2-1.1-1.0
Patch foraging time to switch 0 sec0.71.43.51.81.51.61.8-1.91.91.61.40.70.90.80.80.60.80.7-0.50.50.50.50.91.11.1
Patch foraging water rate 0 sec0.61.24.4-2.1-1.8-1.7-2.01.9-1.9-1.4-1.1-0.2-0.4-0.3-0.3-0.1-0.3-0.1-0.10.10.10.1-0.5-0.6-0.8
Patch foraging water rate 12 sec1.02.05.8-2.4-2.4-2.4-1.91.9-1.9-1.0-0.41.10.81.11.01.11.11.1-1.31.31.31.30.50.50.2
Patch foraging water rate 18 sec3.04.714.3-3.7-3.5-3.6-3.43.8-3.8-3.1-2.7-0.6-0.9-0.4-0.4-0.2-0.0-0.3-0.00.00.00.0-1.5-1.3-1.3
Patch foraging water rate 24 sec2.02.76.4-2.3-1.9-2.2-2.42.5-2.5-2.3-2.2-1.0-1.3-1.0-1.3-1.0-0.8-0.90.8-0.8-0.8-0.8-1.6-1.5-1.5
Patch foraging water rate 6 sec1.62.37.6-2.8-2.6-2.7-2.52.7-2.7-2.0-1.5-0.1-0.3-0.00.00.10.10.0-0.10.10.10.1-0.7-0.7-0.8
Seeking ratio, delayed vs. immediate footshock0.30.30.70.50.60.70.1-0.30.3-0.1-0.3-0.8-0.6-0.5-0.5-0.5-0.8-0.50.7-0.7-0.7-0.7-0.5-0.4-0.4
Distance traveled before self-admin0.70.92.00.70.20.11.0-0.90.91.01.11.11.21.21.01.01.31.1-0.60.60.60.61.01.21.4
Distance traveled after self-admin0.60.71.6-0.7-0.8-0.7-0.20.2-0.20.41.11.31.21.00.90.90.91.0-0.70.70.70.71.21.01.0
Extensor digitorum longus weight0.10.51.00.60.70.70.4-0.20.2-0.1-0.5-0.9-0.9-0.7-1.0-0.8-0.8-0.70.7-0.7-0.7-0.7-0.6-0.6-0.8
Bone: elastic displacement1.01.22.70.60.30.10.8-1.01.01.11.10.70.91.21.21.20.81.3-1.31.31.31.31.61.50.9
Bone: elastic work1.62.25.72.01.61.42.4-2.22.22.12.01.01.20.90.91.00.90.9-0.80.80.80.81.41.21.2
Bone: endosteal estimation1.94.17.42.42.72.21.4-1.41.40.2-1.0-2.0-2.0-2.4-2.5-2.1-1.8-2.42.3-2.3-2.3-2.3-2.3-2.1-1.5
Bone: endosteal perimeter1.53.15.41.01.41.10.2-0.10.1-0.8-1.5-2.1-2.1-2.2-2.3-2.0-1.9-2.22.1-2.1-2.1-2.1-2.2-2.2-1.7
Epididymis fat weight3.210.837.76.16.15.85.5-5.35.33.62.0-1.2-0.7-2.0-1.8-1.5-1.3-1.81.5-1.5-1.5-1.5-0.4-0.60.3
Delta time in closed arm before/after self-admin0.20.10.4-0.6-0.4-0.0-0.60.5-0.5-0.3-0.5-0.2-0.4-0.2-0.2-0.2-0.3-0.1-0.50.50.50.5-0.1-0.1-0.5
Delta time in open arm before/after self-admin1.11.13.21.81.81.51.2-1.71.71.00.8-0.00.0-0.3-0.4-0.4-0.3-0.41.3-1.3-1.3-1.3-0.10.00.2
Diff in mean of infusions in LGA sessions2.02.44.10.2-0.1-0.50.7-0.90.91.51.72.02.01.91.91.92.01.9-1.51.51.51.51.81.92.0
Delay discount exponential model param1.51.74.00.91.31.7-0.1-0.70.7-0.2-0.9-1.8-1.6-1.5-1.5-1.5-2.0-1.51.3-1.3-1.3-1.3-1.1-1.2-1.0
Extinction: sum of active levers before priming0.20.30.8-0.7-0.4-0.6-0.90.6-0.6-0.7-0.7-0.6-0.6-0.2-0.3-0.3-0.6-0.30.3-0.3-0.3-0.3-0.4-0.3-0.6
Active lever presses in extinction session 60.60.62.11.41.41.41.2-1.11.10.60.3-0.9-0.6-0.3-0.5-0.5-0.9-0.40.1-0.1-0.1-0.10.1-0.1-0.5
Bone: final force0.20.21.20.90.70.71.1-0.80.80.70.50.20.3-0.1-0.00.10.3-0.1-0.00.00.00.0-0.1-0.00.3
Bone: final moment0.10.21.00.80.70.61.0-0.70.70.70.40.20.20.1-0.00.10.3-0.0-0.20.20.20.2-0.10.10.3
Food consumed during 24 hour testing period0.00.10.40.60.40.20.6-0.10.10.3-0.10.10.1-0.0-0.00.00.4-0.10.0-0.0-0.0-0.0-0.3-0.20.3
Glucose0.61.02.31.31.21.30.7-0.60.60.0-0.6-1.5-1.3-1.0-1.1-1.2-1.3-1.10.8-0.8-0.8-0.8-0.6-0.8-0.8
Heart weight0.71.03.01.71.51.71.6-1.11.10.40.1-1.0-0.7-0.8-0.8-0.8-0.8-0.81.1-1.1-1.1-1.1-0.5-0.4-0.4
Delay discount hyperbolic model param1.31.53.70.40.91.4-0.5-0.30.3-0.5-1.0-1.7-1.5-1.4-1.4-1.4-1.9-1.41.3-1.3-1.3-1.3-1.1-1.2-1.1
Intermittent access intake day 1-15 change0.40.82.41.41.31.50.8-0.90.90.1-0.4-1.1-1.0-0.8-0.8-0.9-1.0-0.90.8-0.8-0.8-0.8-0.7-0.5-0.4
Intermittent access intake escalation0.20.51.71.11.01.30.6-0.70.70.1-0.4-0.9-0.8-0.6-0.6-0.6-0.8-0.60.6-0.6-0.6-0.6-0.6-0.3-0.2
Intermittent access intake escalation 20.60.72.41.41.41.60.9-1.11.10.4-0.1-0.6-0.6-0.7-0.7-0.7-0.5-0.70.7-0.7-0.7-0.7-0.7-0.4-0.0
Intermitt. access day 1 inactive lever presses0.31.12.9-0.8-0.7-0.2-1.11.2-1.2-1.6-1.7-1.4-1.4-0.8-0.8-0.8-1.1-0.80.8-0.8-0.8-0.8-1.3-0.9-1.4
Intermitt. access day 15 inactive lever presses1.93.87.70.30.81.6-1.00.4-0.4-1.7-2.3-2.8-2.6-2.1-2.1-2.2-2.5-2.22.1-2.1-2.1-2.1-2.3-2.0-2.1
Intermitt. access escalation Index0.20.20.60.70.80.50.8-0.60.60.60.6-0.1-0.1-0.2-0.2-0.2-0.5-0.20.2-0.2-0.2-0.20.50.1-0.5
Intermittent access day 1 total infusions0.00.00.10.1-0.20.00.2-0.00.0-0.20.0-0.3-0.10.30.30.1-0.00.2-0.30.30.30.30.40.3-0.1
Intermittent access day 15 total infusions0.30.41.71.20.71.30.8-0.70.7-0.1-0.3-1.1-0.8-0.3-0.3-0.4-0.7-0.30.3-0.3-0.3-0.3-0.2-0.1-0.3
Intermittent access terminal intake (last 3 days)0.30.42.11.40.91.41.0-1.01.00.3-0.1-0.9-0.5-0.1-0.1-0.1-0.5-0.10.1-0.1-0.1-0.10.10.2-0.1
Intermittent access total infusions0.40.41.30.90.81.20.5-0.70.7-0.1-0.2-1.0-0.8-0.5-0.5-0.6-0.9-0.50.5-0.5-0.5-0.5-0.2-0.3-0.5
Intermittent access day 1 locomotion0.60.71.4-0.5-1.0-0.80.20.3-0.3-0.00.60.80.81.01.01.00.91.0-1.01.01.01.01.20.90.5
Intermittent access day 15 total locomotion0.10.20.60.70.70.80.6-0.60.60.10.3-0.3-0.2-0.3-0.3-0.5-0.4-0.40.3-0.3-0.3-0.30.1-0.10.1
Intermittent access total locomotion0.10.20.6-0.1-0.4-0.30.2-0.00.00.00.40.30.40.50.50.40.30.5-0.50.50.50.50.80.60.4
Intermittent access standard deviation0.10.10.3-0.0-0.10.4-0.50.1-0.1-0.4-0.5-0.6-0.5-0.2-0.2-0.3-0.5-0.30.2-0.2-0.2-0.2-0.3-0.2-0.1
Left kidney weight0.42.17.22.72.72.72.5-2.22.21.40.8-0.8-0.5-0.7-0.7-0.6-0.8-0.80.7-0.7-0.7-0.7-0.1-0.2-0.2
Right kidney weight0.20.82.71.51.61.61.2-1.11.10.50.1-0.9-0.7-0.7-0.8-0.8-0.9-0.80.5-0.5-0.5-0.5-0.3-0.4-0.4
Cocaine induced anxiety0.20.30.7-0.6-0.6-0.4-0.60.8-0.8-0.8-0.5-0.7-0.6-0.3-0.3-0.3-0.6-0.30.3-0.3-0.3-0.3-0.0-0.5-0.5
Post-drug Anxiety0.10.10.50.70.70.70.6-0.60.60.30.1-0.3-0.2-0.2-0.2-0.2-0.2-0.20.2-0.2-0.2-0.20.1-0.00.1
Baseline Anxiety1.11.34.21.91.91.71.9-2.12.11.81.20.60.60.20.20.20.60.2-0.20.20.20.20.30.70.8
Tail length0.31.22.81.71.71.51.5-1.11.10.70.0-0.7-0.7-1.0-0.9-0.9-0.6-1.11.3-1.3-1.3-1.3-0.8-0.9-0.2
Length with tail1.14.712.53.53.53.43.0-2.52.51.2-0.1-1.8-1.6-1.9-2.0-2.0-1.6-2.02.0-2.0-2.0-2.0-1.4-1.4-0.8
Length without tail0.92.810.42.82.83.22.4-2.12.11.00.1-1.2-1.0-1.2-1.4-1.4-1.2-1.31.3-1.3-1.3-1.3-0.9-0.7-0.5
Times rat made contact with spout1.11.34.92.22.11.91.9-1.81.81.20.7-0.5-0.3-0.5-0.5-0.5-0.5-0.70.5-0.5-0.5-0.50.1-0.3-0.1
Lifetime Intake0.30.40.80.80.80.90.3-0.60.6-0.1-0.2-0.9-0.7-0.6-0.6-0.7-0.9-0.60.6-0.6-0.6-0.6-0.3-0.4-0.5
Liver weight, left1.21.94.72.02.21.81.5-1.31.30.5-0.2-1.2-1.1-1.7-1.5-1.5-1.1-1.61.3-1.3-1.3-1.3-1.2-1.3-0.5
Liver weight, right0.91.64.72.12.22.01.7-1.51.50.80.1-0.9-0.8-1.4-1.1-1.2-0.7-1.21.1-1.1-1.1-1.1-0.9-0.9-0.3
Locomotor activity0.10.10.40.50.30.60.4-0.30.30.20.2-0.2-0.1-0.3-0.2-0.2-0.2-0.30.4-0.4-0.4-0.4-0.1-0.2-0.3
Locomotor testing distance0.00.00.2-0.3-0.50.0-0.20.3-0.3-0.10.10.10.10.00.10.20.00.10.0-0.0-0.0-0.00.1-0.0-0.0
Locomotor testing rearing0.10.20.70.20.50.80.2-0.20.20.20.3-0.2-0.2-0.6-0.5-0.6-0.6-0.60.6-0.6-0.6-0.6-0.2-0.5-0.3
Locomotion in novel chamber1.72.13.5-1.6-0.9-0.9-1.81.7-1.7-1.9-1.5-1.3-1.4-1.2-1.3-1.2-1.6-1.21.5-1.5-1.5-1.5-1.4-1.3-1.8
Locomotion in novel chamber post-restriction1.01.63.5-1.9-1.5-1.3-1.71.9-1.9-1.7-1.3-0.6-0.8-0.9-0.9-0.8-0.9-0.81.0-1.0-1.0-1.0-1.2-1.1-1.6
Fecal boli incidents, locomotor time 11.72.44.0-0.9-0.9-0.9-1.21.7-1.7-1.9-2.0-1.6-1.7-1.5-1.5-1.5-1.3-1.51.6-1.6-1.6-1.6-1.8-1.8-1.7
Change in fecal boli incidents, locomotor task0.10.10.3-0.4-0.10.1-0.5-0.10.10.10.1-0.00.00.30.20.3-0.30.2-0.20.20.20.20.30.3-0.2
Time >=10cm from walls, locomotor time 10.20.20.5-0.6-0.4-0.2-0.70.5-0.5-0.5-0.5-0.2-0.3-0.2-0.2-0.2-0.3-0.20.5-0.5-0.5-0.5-0.5-0.3-0.6
Bouts of movement, locomotor time 10.80.92.9-1.3-1.4-1.7-1.01.5-1.5-1.5-1.3-0.4-0.5-0.4-0.3-0.40.2-0.30.4-0.4-0.4-0.4-1.0-0.8-0.5
Total resting periods, locomotor time 11.21.33.6-1.6-1.6-1.9-1.51.8-1.8-1.8-1.7-0.6-0.8-0.5-0.4-0.5-0.0-0.40.5-0.5-0.5-0.5-1.1-0.9-0.6
Rest time, locomotor task time 11.11.33.1-0.6-0.4-1.0-1.00.9-0.9-1.3-1.8-1.2-1.3-1.2-1.3-1.2-0.7-1.21.2-1.2-1.2-1.2-1.6-1.4-1.0
Distance moved, locomotor task time 12.74.06.9-0.8-1.4-0.9-0.00.2-0.20.81.62.12.22.62.62.62.12.5-2.62.62.62.62.42.41.8
Vertical activity count, locomotor time 10.30.71.60.80.50.71.0-0.80.81.11.31.01.00.80.80.80.90.8-0.70.70.70.70.90.90.8
Time >=10cm from walls, locomotor time 20.40.61.81.31.31.21.2-1.11.10.60.2-0.5-0.5-0.6-0.6-0.6-0.5-0.60.8-0.8-0.8-0.8-0.3-0.3-0.2
Bouts of movement, locomotor time 20.10.10.40.30.0-0.20.6-0.10.10.30.60.30.40.30.30.30.40.3-0.40.40.40.40.60.40.5
Total resting periods, locomotor time 20.00.10.40.40.10.10.6-0.20.20.30.40.00.20.00.10.00.10.1-0.10.10.10.10.30.10.3
Rest time, locomotor task time 20.10.10.4-0.2-0.2-0.3-0.40.2-0.2-0.4-0.6-0.5-0.4-0.2-0.2-0.2-0.1-0.20.1-0.1-0.1-0.1-0.4-0.3-0.2
Distance moved, locomotor task time 21.01.21.7-0.9-1.2-1.0-0.40.7-0.70.00.61.31.21.31.31.31.31.3-1.31.31.31.31.11.01.1
Vertical activity count, locomotor time 20.20.20.70.0-0.1-0.10.3-0.10.10.50.80.90.70.50.50.50.70.5-0.30.30.30.30.50.50.6
Light reinforcement 10.71.72.80.00.20.0-0.40.8-0.8-1.1-1.4-1.4-1.5-1.6-1.5-1.6-1.2-1.61.4-1.4-1.4-1.4-1.6-1.7-1.7
Light reinforcement 22.43.76.4-0.30.2-0.2-0.91.1-1.1-1.7-1.8-2.4-2.3-2.4-2.3-2.3-2.4-2.42.2-2.2-2.2-2.2-1.9-2.4-2.5
Bone: marrow area1.94.27.32.42.72.21.4-1.31.30.1-1.0-2.1-2.0-2.4-2.5-2.2-1.8-2.42.3-2.3-2.3-2.3-2.3-2.2-1.5
Bone: maximum diameter0.71.32.11.41.51.40.9-0.80.80.1-0.6-1.1-1.0-1.3-1.3-1.0-0.8-1.31.4-1.4-1.4-1.4-1.4-1.3-0.5
Bone: maximum force0.10.20.80.70.70.80.9-0.60.60.50.30.10.1-0.1-0.3-0.10.2-0.20.0-0.0-0.0-0.0-0.3-0.10.1
Bone: maximum moment0.10.20.70.70.70.70.9-0.60.60.60.30.20.20.1-0.20.00.3-0.0-0.20.20.20.2-0.20.10.2
Mean time between licks in bursts0.10.20.5-0.7-0.4-0.4-0.60.7-0.7-0.5-0.2-0.0-0.1-0.4-0.4-0.4-0.4-0.40.4-0.4-0.4-0.4-0.3-0.5-0.3
Mean num. licks in bursts0.20.31.21.00.81.10.6-0.60.60.2-0.3-1.1-0.8-0.3-0.3-0.3-0.8-0.20.3-0.3-0.3-0.3-0.0-0.0-0.4
Cd content in liver0.10.10.20.30.4-0.10.2-0.20.20.2-0.30.3-0.00.1-0.4-0.40.4-0.10.2-0.2-0.2-0.2-0.5-0.00.0
Co content in liver0.30.30.8-0.6-0.7-0.8-0.80.9-0.9-0.7-0.9-0.6-0.60.0-0.3-0.3-0.3-0.10.1-0.1-0.1-0.1-0.3-0.2-0.6
Cu content in liver0.20.31.0-0.7-1.0-0.8-0.60.8-0.8-0.6-0.6-0.0-0.00.40.30.30.40.3-0.40.40.40.4-0.10.10.1
Fe content in liver0.60.72.01.11.01.31.4-1.21.21.11.10.60.70.20.50.50.50.3-0.30.30.30.30.50.50.8
K content in liver2.82.74.1-1.4-1.8-1.7-0.60.5-0.50.41.21.91.91.82.02.01.81.9-2.02.02.02.01.81.51.6
Mg content in liver0.20.20.4-0.2-0.2-0.10.0-0.30.30.30.60.60.60.20.60.60.40.4-0.40.40.40.40.50.30.6
Mn content in liver1.41.62.7-1.1-0.8-1.0-1.61.3-1.3-1.5-1.4-1.5-1.4-1.3-1.0-1.0-1.6-1.11.0-1.0-1.0-1.0-1.0-1.4-1.6
Na content in liver1.81.93.6-0.1-0.30.20.7-0.80.81.31.81.51.71.41.61.61.11.5-1.71.71.71.71.91.61.5
Rb content in liver0.20.20.50.40.30.50.6-0.50.50.40.40.60.60.50.40.40.70.4-0.50.50.50.50.20.40.7
Se content in liver1.01.11.70.60.20.00.9-0.90.91.21.01.11.21.11.21.21.31.2-1.21.21.21.21.11.21.3
Sr content in liver0.70.61.0-0.8-0.6-0.7-0.91.0-1.0-0.9-1.0-0.7-0.8-0.7-0.6-0.6-0.6-0.60.6-0.6-0.6-0.6-0.8-0.8-0.9
Zn content in liver0.40.40.9-0.6-0.8-0.7-0.10.5-0.50.10.40.80.80.60.80.90.90.7-0.60.60.60.60.40.40.7
Bone: minimum diameter0.20.41.41.01.01.20.9-0.80.80.50.2-0.4-0.3-0.6-0.5-0.3-0.4-0.60.5-0.5-0.5-0.5-0.4-0.6-0.2
Time in familiar zone, hab. session 11.81.72.70.40.2-0.10.5-0.90.91.31.31.61.51.51.71.31.51.4-1.61.61.61.61.41.51.6
Time in novel zone, hab. session 11.91.93.70.30.50.80.10.2-0.2-0.8-0.9-1.5-1.5-1.7-1.9-1.5-1.6-1.61.9-1.9-1.9-1.9-1.5-1.5-1.4
Total zone transitions, hab. session 10.40.62.7-1.2-1.4-1.6-1.21.1-1.1-0.7-0.60.10.10.20.40.70.40.5-0.40.40.40.40.30.00.0
Total locomotion distance, hab. session 10.71.03.6-1.7-1.9-1.8-1.51.6-1.6-1.1-0.80.00.10.50.60.80.40.7-0.60.60.60.60.20.2-0.0
Locomotion velocity, hab. session 10.91.34.5-2.0-2.1-2.1-1.71.7-1.7-1.1-0.70.30.30.60.81.00.60.8-0.70.70.70.70.30.30.1
Time in familiar zone, hab. session 20.20.20.5-0.4-0.3-0.2-0.70.5-0.5-0.7-0.4-0.5-0.5-0.3-0.5-0.5-0.7-0.40.4-0.4-0.4-0.4-0.3-0.4-0.6
Time in novel zone, hab. session 20.30.31.01.01.00.81.0-0.80.80.60.1-0.3-0.3-0.5-0.4-0.3-0.2-0.40.5-0.5-0.5-0.5-0.3-0.3-0.1
Total zone transitions, hab. session 20.81.01.7-0.10.0-0.3-0.40.5-0.5-0.7-1.0-1.2-1.1-1.3-1.3-1.0-1.0-1.11.3-1.3-1.3-1.3-1.2-1.3-1.0
Total locomotion distance, hab. session 22.43.14.9-1.0-0.6-0.5-1.31.4-1.4-1.9-2.0-2.0-2.1-1.9-1.9-1.8-2.0-1.82.0-2.0-2.0-2.0-1.9-2.0-2.2
Locomotion velocity, hab. session 21.92.53.9-1.4-1.0-1.0-1.71.7-1.7-1.9-1.9-1.7-1.7-1.5-1.5-1.4-1.7-1.41.5-1.5-1.5-1.5-1.6-1.7-2.0
Novel to familiar place preference ratio0.30.30.70.30.60.50.1-0.30.30.1-0.1-0.1-0.2-0.8-0.8-0.5-0.2-0.70.8-0.8-0.8-0.8-0.8-0.8-0.2
Novelty place preference0.20.20.50.40.60.40.2-0.40.40.20.10.20.0-0.7-0.7-0.4-0.0-0.60.6-0.6-0.6-0.6-0.6-0.7-0.0
Time in novel zone, NPP test0.60.61.10.81.00.80.5-0.70.70.30.1-0.1-0.2-1.0-1.0-0.7-0.3-1.01.0-1.0-1.0-1.0-0.9-1.0-0.2
Total zone transitions, NPP test0.30.41.9-1.0-1.0-1.4-1.01.0-1.0-0.8-0.8-0.3-0.3-0.2-0.30.1-0.0-0.00.3-0.3-0.3-0.3-0.4-0.4-0.3
Total locomotion distance, NPP test1.62.23.5-1.5-1.2-1.3-1.71.8-1.8-1.8-1.9-1.4-1.5-1.3-1.4-1.1-1.2-1.11.5-1.5-1.5-1.5-1.6-1.4-1.6
Locomotion velocity, NPP test1.42.04.0-1.8-1.5-1.7-1.92.0-2.0-1.8-1.8-1.1-1.2-0.9-1.1-0.7-0.9-0.71.1-1.1-1.1-1.1-1.3-1.1-1.4
Intraocular pressure1.42.04.1-1.1-0.7-1.4-1.61.5-1.5-1.8-2.0-1.2-1.5-1.2-1.3-1.2-0.9-1.21.4-1.4-1.4-1.4-1.8-1.5-1.4
Delta distance traveled before/after self-admin0.20.21.2-1.1-0.7-0.7-0.90.7-0.7-0.20.50.60.40.00.10.1-0.10.1-0.20.20.20.20.4-0.0-0.1
Delta ambulatory time before/after self-admin0.20.20.8-0.9-0.6-0.5-0.80.7-0.7-0.30.20.30.1-0.3-0.3-0.3-0.4-0.30.2-0.2-0.2-0.20.0-0.3-0.4
Parametrial fat weight6.816.060.77.87.66.66.9-6.56.54.62.7-1.2-0.7-2.0-1.9-1.9-1.5-1.91.7-1.7-1.7-1.70.1-0.30.4
Pavlov. Cond. lever latency3.03.77.21.31.61.70.4-0.30.3-0.8-1.4-2.7-2.4-2.3-2.2-2.5-2.7-2.32.2-2.2-2.2-2.2-1.8-1.8-2.1
Pavlov. Cond. magazine entry latency1.21.52.50.20.00.20.6-0.80.81.41.61.61.61.51.21.41.31.3-1.31.31.31.31.51.41.3
Pavlov. Cond. change in total contacts3.94.18.4-1.3-1.5-1.4-0.30.2-0.21.01.62.92.62.52.32.52.72.4-2.42.42.42.41.92.12.1
Pavlov. Cond. index score3.44.28.1-0.7-1.1-1.00.2-0.30.31.42.02.92.72.62.42.62.62.5-2.32.32.32.32.22.22.3
Pavlov. Cond. latency score3.24.08.0-1.2-1.4-1.4-0.20.1-0.11.11.82.82.62.52.32.52.62.4-2.32.32.32.32.12.02.2
Pavlov. Cond. lever contacts2.93.56.7-0.7-1.1-1.20.1-0.20.21.21.52.52.42.22.22.52.62.2-2.12.12.12.11.91.92.3
Pavlov. Cond. magazine entry number1.62.03.6-0.20.1-0.0-0.70.8-0.8-1.4-1.6-1.9-1.8-1.8-1.5-1.6-1.7-1.61.5-1.5-1.5-1.5-1.6-1.6-1.6
Pavlov. Cond. intertrial magazine entries4.85.88.3-0.9-0.2-0.2-1.81.6-1.6-2.3-2.7-2.8-2.8-2.7-2.6-2.6-2.8-2.72.7-2.7-2.7-2.7-2.8-2.8-2.9
Pavlov. Cond. lever-magazine prob. diff.4.25.29.9-0.6-1.0-0.80.4-0.50.51.72.33.13.02.82.62.92.92.7-2.62.62.62.62.52.52.6
Pavlov. Cond. response bias2.73.36.20.0-0.4-0.30.7-0.80.81.71.92.52.42.22.02.32.42.1-2.02.02.02.02.02.02.2
Pavlov. Cond. lever latency1.52.08.0-2.8-2.7-2.4-2.52.3-2.3-1.8-1.00.20.00.40.40.50.20.4-0.10.10.10.1-0.3-0.2-0.5
Pavlov. Cond. magazine entry latency3.03.65.52.02.32.01.0-0.90.9-0.1-1.0-2.2-2.0-2.4-2.2-2.3-2.1-2.32.2-2.2-2.2-2.2-1.8-1.9-1.3
Pavlov. Cond. change in total contacts1.52.59.13.02.92.72.7-2.72.72.11.4-0.20.1-0.3-0.4-0.3-0.3-0.3-0.20.20.20.20.60.50.7
Pavlov. Cond. index score2.02.79.83.03.12.82.4-2.32.31.40.5-1.0-0.8-1.3-1.3-1.4-1.1-1.31.0-1.0-1.0-1.0-0.4-0.6-0.2
Pavlov. Cond. latency score1.52.07.52.72.72.42.2-2.12.11.40.6-0.7-0.5-1.0-1.0-1.0-0.7-1.00.8-0.8-0.8-0.8-0.2-0.40.1
Pavlov. Cond. lever contacts1.62.28.62.92.92.62.6-2.42.41.71.0-0.4-0.2-0.7-0.7-0.8-0.4-0.70.4-0.4-0.4-0.40.0-0.00.3
Pavlov. Cond. magazine entry number1.82.26.1-2.4-2.5-2.3-1.61.5-1.5-0.70.21.41.21.51.51.51.31.5-1.31.31.31.30.91.00.5
Pavlov. Cond. intertrial magazine entries0.60.92.2-1.4-1.5-1.4-0.80.9-0.9-0.20.41.31.10.91.01.01.11.0-1.01.01.01.00.70.60.4
Pavlov. Cond. lever-magazine prob. diff.1.92.69.73.13.12.82.6-2.42.41.70.9-0.7-0.5-1.0-1.0-1.0-0.8-0.90.7-0.7-0.7-0.7-0.1-0.20.1
Pavlov. Cond. response bias2.23.09.63.03.12.92.3-2.12.11.20.2-1.4-1.2-1.6-1.6-1.6-1.3-1.51.2-1.2-1.2-1.2-0.8-0.9-0.4
Time in closed arm before self-admin0.00.00.30.0-0.20.1-0.10.1-0.1-0.1-0.5-0.5-0.40.00.0-0.0-0.2-0.1-0.10.10.10.1-0.2-0.1-0.2
Time in closed arm after self-admin0.40.41.6-0.8-0.9-0.2-0.90.9-0.9-0.7-1.3-0.9-0.8-0.3-0.3-0.3-0.5-0.2-0.50.50.50.5-0.5-0.4-0.8
Time in open arm before self-admin0.10.20.6-0.00.0-0.10.3-0.10.10.20.80.60.50.40.40.40.20.4-0.40.40.40.40.70.40.3
Time in open arm after self-admin0.91.03.31.31.10.71.2-1.51.51.21.80.91.10.70.60.60.50.70.5-0.5-0.5-0.51.11.01.0
Bone: periosteal estimation0.81.63.51.81.91.81.3-1.21.20.4-0.3-1.2-1.1-1.4-1.4-1.1-0.9-1.41.3-1.3-1.3-1.3-1.3-1.3-0.7
Bone: periosteal perimeter0.61.01.70.71.01.00.3-0.30.3-0.2-0.6-1.2-1.1-1.3-1.3-1.1-1.1-1.31.2-1.2-1.2-1.2-1.2-1.3-0.8
Bone: post-yield work0.30.41.1-0.00.40.4-0.40.2-0.2-0.4-0.7-0.7-0.7-0.5-1.1-0.9-0.7-0.70.6-0.6-0.6-0.6-0.9-0.6-0.6
Progressive ratio test 1 active lever presses0.10.10.60.80.50.60.6-0.60.60.20.1-0.4-0.30.00.0-0.1-0.4-0.0-0.00.00.00.00.20.1-0.2
Progressive ratio test 1 breakpoint0.10.20.80.90.60.70.7-0.70.70.30.1-0.4-0.20.00.0-0.1-0.3-0.0-0.00.00.00.00.20.2-0.1
Progressive ratio test 1 inactive lever presses1.72.44.10.10.60.5-0.60.4-0.4-1.3-1.8-2.0-2.0-1.8-1.8-1.9-1.8-1.81.8-1.8-1.8-1.8-1.9-1.8-1.7
Progressive ratio test 2 active lever presses0.20.20.40.60.50.50.3-0.40.4-0.1-0.2-0.7-0.5-0.5-0.5-0.6-0.5-0.50.5-0.5-0.5-0.5-0.3-0.40.0
Progressive ratio test 2 breakpoint0.20.30.50.70.60.50.4-0.50.5-0.1-0.2-0.7-0.6-0.5-0.5-0.6-0.5-0.50.5-0.5-0.5-0.5-0.3-0.4-0.0
Progressive ratio test 2 inactive lever presses2.54.06.81.11.61.30.2-0.30.3-0.9-1.4-2.4-2.3-2.6-2.6-2.6-2.4-2.52.6-2.6-2.6-2.6-2.1-2.2-1.6
Incentive Sensitization - Responses0.71.02.00.20.60.2-0.30.1-0.1-0.6-0.7-1.1-1.1-1.3-1.3-1.4-1.2-1.31.3-1.3-1.3-1.3-1.0-1.2-0.7
Incentive Sensitization - Breakpoint0.91.12.10.30.70.4-0.20.0-0.0-0.5-0.7-1.2-1.2-1.4-1.4-1.4-1.3-1.31.4-1.4-1.4-1.4-1.0-1.2-0.8
Sum of active levers in priming session hrs 5-60.30.30.9-0.7-0.6-0.9-0.90.6-0.6-0.6-0.9-0.6-0.60.10.00.0-0.5-0.0-0.10.10.10.1-0.1-0.2-0.7
Progressive ratio1.93.04.4-1.5-0.9-1.0-2.01.7-1.7-2.1-2.1-1.7-1.8-1.5-1.7-1.5-1.7-1.41.9-1.9-1.9-1.9-1.8-1.6-2.1
Food seeking constrained by brief footshock1.51.93.2-1.5-1.8-1.8-1.30.9-0.9-0.20.51.11.11.61.51.60.91.5-1.81.81.81.81.51.30.7
Seeking ratio, punishment vs. effort2.63.85.51.10.50.41.5-1.51.52.12.32.02.21.92.12.01.91.9-2.32.32.32.32.32.02.3
Retroperitoneal fat weight7.130.3113.910.710.19.410.0-9.39.37.04.6-0.40.3-1.5-1.3-1.2-0.4-1.41.2-1.2-1.2-1.20.80.71.9
Reaction time number correct1.73.24.6-1.3-0.8-1.0-1.62.0-2.0-2.1-2.0-1.5-1.8-1.9-2.1-1.9-1.6-1.81.8-1.8-1.8-1.8-2.0-2.1-2.0
Reaction time mean minus median0.51.23.91.92.01.91.3-1.81.81.10.5-0.6-0.4-0.7-0.7-0.6-0.7-0.60.8-0.8-0.8-0.8-0.2-0.1-0.1
Reaction time mean minus median AUC0.71.74.31.92.11.81.3-1.61.60.80.1-1.0-0.9-1.3-1.3-1.2-1.2-1.11.4-1.4-1.4-1.4-0.7-0.7-0.7
Reaction time num false alarms0.91.24.8-1.9-2.2-1.8-1.62.0-2.0-1.3-1.2-0.2-0.20.20.50.50.30.3-0.50.50.50.5-0.2-0.3-0.0
Reaction time num false alarms AUC0.61.03.9-1.8-2.0-1.7-1.51.8-1.8-1.1-1.0-0.1-0.10.10.50.50.40.2-0.40.40.40.4-0.2-0.30.0
Reaction time trials correct on left1.73.24.6-1.3-0.8-1.0-1.62.0-2.0-2.1-2.0-1.5-1.8-1.9-2.1-1.9-1.6-1.81.8-1.8-1.8-1.8-2.0-2.1-2.0
Reaction time trials on left1.83.55.1-1.3-0.7-0.9-1.62.0-2.0-2.1-2.0-1.6-1.9-2.1-2.3-2.0-1.7-1.91.9-1.9-1.9-1.9-2.1-2.2-2.1
Reaction time mean1.22.07.32.72.72.22.2-2.22.21.40.6-0.6-0.4-1.0-0.7-0.6-0.5-0.80.9-0.9-0.9-0.9-0.3-0.4-0.0
Reaction time mean AUC1.01.55.82.42.31.92.0-2.02.01.30.7-0.5-0.3-0.8-0.6-0.4-0.4-0.60.8-0.8-0.8-0.8-0.2-0.20.0
Median of all reaction times1.11.56.22.52.41.92.0-2.02.01.30.6-0.5-0.3-0.8-0.5-0.5-0.3-0.70.7-0.7-0.7-0.7-0.3-0.30.1
Reaction time omissions1.11.72.81.11.61.20.5-0.70.70.1-0.3-1.1-1.2-1.7-1.6-1.5-1.5-1.61.7-1.7-1.7-1.7-1.2-1.3-1.0
Reaction time false alarm rate0.60.81.9-1.0-1.4-1.1-0.70.7-0.7-0.2-0.20.40.50.81.31.10.90.9-1.11.11.11.10.60.40.8
Reaction time premature initiation rate0.10.10.5-0.0-0.3-0.2-0.20.4-0.4-0.4-0.7-0.5-0.5-0.2-0.1-0.1-0.2-0.30.0-0.0-0.0-0.0-0.5-0.5-0.2
Reaction time premature initiations0.81.32.8-0.8-0.8-0.8-1.11.4-1.4-1.5-1.7-1.3-1.3-1.1-1.1-1.0-0.9-1.10.9-0.9-0.9-0.9-1.4-1.4-1.2
Std. dev. reaction times0.81.55.02.22.22.01.7-2.02.01.30.6-0.5-0.4-0.7-0.7-0.6-0.6-0.60.8-0.8-0.8-0.8-0.2-0.20.0
Reaction time trials completed1.83.55.1-1.3-0.7-0.9-1.62.0-2.0-2.1-2.0-1.6-1.9-2.1-2.3-2.0-1.7-1.91.9-1.9-1.9-1.9-2.1-2.2-2.1
Reaction time trials AUC2.24.36.3-1.3-0.7-0.8-1.62.1-2.1-2.3-2.3-1.9-2.2-2.3-2.5-2.3-2.0-2.22.1-2.1-2.1-2.1-2.4-2.4-2.4
Run reversals in cocaine runway, females1.11.13.51.81.81.41.8-1.91.91.61.40.30.4-0.2-0.2-0.3-0.1-0.10.1-0.1-0.1-0.10.50.30.5
Run reversals in cocaine runway, males2.52.54.11.50.91.42.0-1.71.72.01.91.51.61.41.51.41.51.4-1.41.41.41.41.61.71.9
Latency to leave start box in cocaine runway1.01.11.9-0.8-0.5-0.2-1.21.1-1.1-1.3-1.0-1.2-1.1-0.9-1.0-1.0-1.4-0.91.2-1.2-1.2-1.2-0.8-0.9-1.3
Latency to leave start box in cocaine runway, F1.01.22.70.10.30.5-0.30.4-0.4-0.9-1.0-1.2-1.2-1.1-1.2-1.2-1.1-1.11.6-1.6-1.6-1.6-1.2-1.0-1.0
Latency to leave start box in cocaine runway, M0.90.82.9-1.5-1.1-0.7-1.71.4-1.4-1.2-0.7-0.9-0.7-0.4-0.4-0.4-1.2-0.40.4-0.4-0.4-0.4-0.1-0.5-1.3
Std. dev. time between licks in bursts0.20.31.1-0.9-0.8-1.1-0.80.9-0.9-0.6-0.30.30.00.00.00.00.10.1-0.00.00.00.0-0.1-0.1-0.4
Total sessions with >9 infusions0.30.40.80.90.90.90.5-0.70.70.20.0-0.7-0.5-0.6-0.6-0.7-0.8-0.60.6-0.6-0.6-0.6-0.2-0.4-0.2
Short access day 1 total inactive lever presses2.63.56.0-0.6-0.20.1-1.11.2-1.2-2.0-2.4-2.4-2.4-1.9-1.9-2.0-2.2-2.01.9-1.9-1.9-1.9-2.2-2.2-2.4
Short access day 10 total inactive lever presses2.15.18.1-0.00.60.8-0.90.9-0.9-1.9-2.5-2.7-2.8-2.7-2.7-2.7-2.6-2.62.7-2.7-2.7-2.7-2.8-2.6-2.6
Short access day 1 total infusions0.60.81.3-0.8-0.5-0.7-1.10.9-0.9-1.1-1.1-0.8-0.9-0.8-0.8-0.9-0.8-0.90.8-0.8-0.8-0.8-1.0-1.0-0.9
Short access day 10 total infusions0.40.51.00.50.50.80.1-0.20.2-0.4-0.5-1.0-0.9-0.7-0.7-0.8-1.0-0.80.7-0.7-0.7-0.7-0.6-0.6-0.7
Short access total infusions0.30.40.80.70.80.80.3-0.50.50.0-0.2-0.8-0.7-0.7-0.7-0.8-0.9-0.80.7-0.7-0.7-0.7-0.4-0.6-0.5
Short access day 1 locomotion0.10.10.30.20.30.40.1-0.30.30.10.2-0.3-0.2-0.3-0.3-0.4-0.5-0.40.3-0.3-0.3-0.30.1-0.3-0.1
Short access day 10 total locomotion0.10.30.6-0.6-0.6-0.4-0.60.7-0.7-0.7-0.8-0.3-0.5-0.4-0.4-0.4-0.3-0.40.4-0.4-0.4-0.4-0.6-0.5-0.6
Short access total locomotion0.10.10.3-0.2-0.4-0.40.10.2-0.20.00.40.40.40.30.30.20.20.3-0.30.30.30.30.60.20.3
One hour access (0.3 mA shock)0.40.51.3-0.30.0-0.1-0.90.2-0.2-0.7-0.8-1.0-0.9-0.6-0.6-0.7-1.1-0.70.6-0.6-0.6-0.6-0.5-0.6-1.0
Compulsive drug intake0.81.04.2-1.9-1.5-1.8-2.01.2-1.2-0.7-0.60.50.20.70.70.70.30.7-0.70.70.70.70.40.3-0.5
One hour access (shock baseline)0.20.41.81.10.91.30.9-0.90.90.30.2-0.5-0.3-0.4-0.4-0.5-0.4-0.40.4-0.4-0.4-0.4-0.2-0.10.2
Social response proportion1.51.75.82.42.42.12.1-2.32.31.81.4-0.10.1-0.2-0.3-0.2-0.4-0.20.0-0.0-0.0-0.00.80.50.2
Social responses0.10.10.80.80.50.60.9-0.40.40.30.30.00.10.00.00.00.20.0-0.20.20.20.20.20.10.2
Social time0.50.73.21.41.21.11.8-1.11.11.11.10.40.40.30.00.00.20.2-0.40.40.40.40.80.60.5
Soleus weight0.10.30.70.20.40.1-0.10.1-0.1-0.3-0.5-0.6-0.7-0.6-0.8-0.7-0.5-0.60.7-0.7-0.7-0.7-0.7-0.6-0.8
Bone: stiffness0.20.30.80.30.40.60.40.0-0.0-0.3-0.3-0.5-0.4-0.7-0.8-0.6-0.4-0.70.6-0.6-0.6-0.6-0.9-0.7-0.6
Tibialis anterior weight0.30.93.41.71.81.71.3-1.41.41.00.4-0.4-0.4-0.5-0.8-0.6-0.4-0.60.8-0.8-0.8-0.8-0.3-0.2-0.2
Time to tail flick, vehicle, before self-admin1.31.33.61.21.31.50.5-0.60.6-0.2-0.9-1.9-1.6-1.2-1.2-1.2-1.6-1.21.0-1.0-1.0-1.0-0.9-1.0-1.3
Time to tail flick, vehicle, after self-admin0.20.20.7-0.1-0.6-0.40.20.2-0.2-0.1-0.50.00.10.60.70.70.90.7-0.60.60.60.60.10.50.3
Time to tail flick, test, before self-admin0.30.30.6-0.3-0.5-0.6-0.40.2-0.2-0.2-0.30.00.10.70.60.60.30.7-0.80.80.80.80.30.60.1
Time to tail flick, test, after self-admin3.43.56.9-0.4-0.10.4-1.11.2-1.2-2.1-2.5-2.2-2.3-1.9-1.9-1.9-1.7-1.82.3-2.3-2.3-2.3-2.6-2.0-2.1
Delta time to tail flick, vehicle, before/after SA0.40.41.2-0.9-1.1-1.1-0.60.9-0.9-0.6-0.60.50.30.40.40.40.90.4-0.30.30.30.3-0.30.10.4
Delta time to tail flick, test, before/after SA1.92.04.3-0.10.20.5-0.40.6-0.6-1.3-1.3-1.3-1.4-1.5-1.5-1.5-1.2-1.52.1-2.1-2.1-2.1-1.9-1.5-1.3
Tibia length0.82.38.93.02.32.22.8-2.52.51.91.2-0.10.20.40.30.30.20.2-0.80.80.80.81.00.80.8
Ambulatory time before self-admin0.60.81.70.90.60.41.2-1.11.11.11.10.91.11.00.80.81.10.9-0.50.50.50.50.91.11.3
Ambulatory time after self-admin0.60.71.9-0.5-0.5-0.5-0.10.0-0.00.61.21.41.30.90.80.81.00.9-0.60.60.60.61.10.91.1
Bone: tissue strength0.40.41.21.01.10.71.0-1.11.11.10.70.20.20.2-0.00.00.10.1-0.20.20.20.20.30.40.2
Total heroin consumption1.31.53.5-0.10.40.0-0.70.4-0.4-0.9-1.3-1.8-1.7-1.3-1.4-1.4-1.9-1.41.2-1.2-1.2-1.2-1.1-1.4-1.6
Bone: trabecular number0.10.10.3-0.5-0.4-0.3-0.30.2-0.2-0.00.30.50.40.50.20.50.40.4-0.20.20.20.20.30.30.1
Bone: trabecular spacing0.60.82.51.61.21.51.5-1.41.41.20.80.20.40.10.40.50.50.2-0.20.20.20.20.30.31.3
Bone: trabecular thickness0.20.20.5-0.4-0.4-0.7-0.10.2-0.20.10.20.50.40.50.40.40.50.4-0.60.60.60.60.50.4-0.1
Bone: trabecular tissue density0.81.22.40.60.40.41.1-1.11.11.21.51.41.41.01.11.11.21.0-1.01.01.01.01.11.11.4
Water consumed over 24 hours1.01.42.40.40.40.4-0.10.2-0.2-0.8-1.3-1.5-1.5-1.4-1.4-1.4-1.2-1.51.4-1.4-1.4-1.4-1.5-1.5-1.2
Number of responses in last shaping day1.11.22.6-0.9-0.5-0.4-1.21.1-1.1-1.4-1.6-1.1-1.2-1.0-1.0-1.0-0.8-1.01.0-1.0-1.0-1.0-1.5-1.2-0.9