Polr3f

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 PL gene expression Polr3f 0.12 0.07 5.9e-07 0.06 0.05 0.06 0.03 3.9e-07 1.5e-06 4.1e-07 1.2e-04
2 OFC alternative TSS NM_001107784.1 0.2 0.15 9.2e-03 0.04 0.07 0.07 0.06 4.4e-02 1.1e-02 8.5e-03 1.4e-02
3 Liver alternative TSS XM_039105045.1 0.04 0.03 5.0e-04 0.03 0.02 0.02 0.03 3.6e-04 1.0e-03 6.5e-03 2.7e-04
4 Liver alternative TSS NM_001107784.1 0.06 0.04 2.5e-04 0.03 0.03 0.02 0.03 2.5e-04 4.3e-04 4.2e-03 1.6e-04
5 Liver mRNA stability Polr3f 0.28 0.11 0.0e+00 0.23 0.23 0.24 0.23 2.0e-25 1.2e-25 7.7e-26 8.7e-26
6 Liver gene expression Polr3f 0.27 0.1 0.0e+00 0.2 0.22 0.22 0.22 1.2e-21 6.6e-24 8.4e-24 4.3e-24
7 LHb mRNA stability Polr3f 0.45 0.28 9.6e-04 0.12 0.05 0.06 0.07 1.1e-03 2.5e-02 2.0e-02 1.2e-02
8 IL mRNA stability Polr3f 0.43 0.15 2.7e-08 0.26 0.27 0.3 0.28 4.8e-07 3.9e-07 4.9e-08 2.2e-07
9 Adipose mRNA stability Polr3f 0.4 0.13 0.0e+00 0.23 0.23 0.23 0.23 1.3e-25 1.3e-25 2.9e-25 1.8e-25
10 BLA mRNA stability Polr3f 0.28 0.1 8.4e-15 0.25 0.28 0.25 0.26 2.1e-13 2.3e-15 1.2e-13 2.6e-14
11 Adipose gene expression Polr3f 0.08 0.04 8.1e-10 0.03 0.05 0.03 0.05 1.8e-04 1.3e-06 1.1e-04 5.7e-06
12 OFC mRNA stability Polr3f 0.56 0.15 6.2e-08 0.28 0.14 0.13 0.23 2.3e-07 4.0e-04 5.3e-04 2.6e-06
13 Adipose alternative TSS NM_001107784.1 0.03 0.02 7.6e-04 0.02 0.02 0.02 0.02 3.2e-03 3.5e-03 3.3e-03 3.2e-03
14 PL mRNA stability Polr3f 0.26 0.1 0.0e+00 0.26 0.3 0.3 0.29 7.0e-28 5.0e-34 2.9e-33 3.7e-32
15 Adipose alternative TSS XM_039105045.1 0.03 0.02 7.5e-04 0.03 0.02 0.02 0.02 7.8e-04 2.9e-03 2.9e-03 2.3e-03
16 RMTg mRNA stability Polr3f 0.25 0.14 1.1e-03 0.08 0.01 0.07 0.09 3.6e-03 1.6e-01 5.9e-03 1.9e-03
17 pVTA mRNA stability Polr3f 0.12 0.07 1.9e-04 0.11 0.1 0.09 0.1 2.0e-05 5.0e-05 9.5e-05 4.4e-05
18 Brain mRNA stability Polr3f 0.27 0.1 0.0e+00 0.24 0.29 0.29 0.29 5.8e-22 1.6e-27 1.9e-27 3.9e-27
19 pVTA gene expression Polr3f 0.22 0.12 3.4e-04 0.1 0.08 0.09 0.08 4.3e-05 1.9e-04 1.3e-04 1.9e-04
20 NAcc mRNA stability Polr3f 0.17 0.07 0.0e+00 0.16 0.16 0.18 0.18 4.3e-18 5.5e-18 6.5e-20 6.3e-20

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20
Bone: apparent density0.10.10.80.1-0.0-0.20.20.3-0.20.00.4-0.1-0.0-0.30.30.3-0.20.1-0.20.4-0.20.9-0.3
Area under the delay curve1.81.94.61.01.60.4-0.40.50.9-1.9-2.11.71.81.0-1.1-1.11.6-1.51.4-1.41.5-1.51.4
BMI with tail2.58.228.1-5.1-4.85.3-5.3-5.04.41.0-0.90.30.42.90.20.20.60.0-0.40.60.80.61.2
BMI without tail2.24.615.8-4.0-3.93.4-3.4-3.42.51.20.1-0.9-1.01.11.51.5-0.91.6-1.61.7-0.71.6-0.3
Body weight3.012.544.1-6.6-6.26.3-6.3-5.74.82.50.4-1.1-0.92.21.71.7-0.61.8-1.81.9-0.41.80.2
Weight adjusted by age0.80.92.0-0.2-0.30.00.00.4-0.31.01.4-1.1-0.9-0.91.31.3-1.01.0-1.21.2-1.01.0-1.0
Bone surface0.20.31.0-0.7-1.00.4-0.4-0.70.10.80.5-0.4-0.50.00.80.8-0.50.2-0.30.5-0.40.9-0.2
Bone volume0.40.71.9-0.5-0.70.0-0.0-0.0-0.31.01.1-0.8-0.8-0.61.21.2-0.90.7-0.80.9-0.81.4-0.7
Breakpoint value in progressive ratio session0.20.20.6-0.6-0.80.5-0.5-0.70.20.6-0.1-0.4-0.60.00.40.4-0.50.4-0.40.3-0.40.1-0.1
Number of licking bursts0.20.20.7-0.40.10.5-0.4-0.00.7-0.8-0.40.50.80.5-0.7-0.70.6-0.10.1-0.10.5-0.40.1
Context. condit. distance diff. score0.20.31.5-0.4-0.5-0.00.0-0.1-0.10.20.6-0.4-0.4-0.20.50.5-0.50.6-0.50.9-0.51.2-0.6
Locomotion velocity, session 10.60.71.71.20.8-1.31.31.0-1.1-0.30.0-0.7-1.1-1.1-0.1-0.1-1.00.4-0.40.3-1.0-0.1-0.7
Locomotion distance, session 11.51.96.52.62.5-2.32.32.3-1.7-0.9-0.20.0-0.1-1.2-1.0-1.0-0.1-0.60.6-0.6-0.1-0.9-0.1
Locomotion velocity, session 21.82.16.02.12.4-1.11.21.2-0.4-1.7-1.51.10.80.0-1.8-1.80.9-1.61.6-1.90.9-1.61.2
Locomotion distance, session 22.23.18.22.72.1-2.82.82.9-2.50.11.2-1.3-1.3-2.40.20.2-1.40.9-0.90.6-1.50.8-1.5
Locomotion velocity, session 31.21.44.52.02.0-2.12.11.8-1.5-1.2-0.20.20.2-0.8-0.7-0.70.1-0.40.4-0.50.0-0.5-0.2
Locomotion distance, session 30.70.82.11.31.4-1.21.21.0-0.7-1.3-0.50.60.6-0.1-0.9-0.90.5-0.60.6-0.90.5-0.50.4
Stereotopy head waving bouts, day 30.10.10.5-0.0-0.3-0.20.2-0.1-0.30.70.3-0.5-0.5-0.30.30.3-0.40.3-0.30.2-0.4-0.3-0.3
Stereotopy head waving duration, day 30.10.10.4-0.4-0.50.1-0.1-0.3-0.10.60.2-0.4-0.5-0.20.50.5-0.40.4-0.30.4-0.4-0.3-0.3
Locomotion velocity, session 70.50.61.51.11.1-1.21.21.2-1.00.10.8-0.7-0.7-1.2-0.2-0.2-0.70.1-0.10.1-0.50.3-0.4
Locomotion distance, session 70.50.71.70.20.1-0.70.60.7-0.80.81.3-1.2-1.1-1.30.50.5-1.10.7-0.70.7-0.90.7-0.8
Stereotopy head waving bouts, day 70.00.00.2-0.2-0.20.2-0.2-0.30.2-0.1-0.0-0.1-0.10.0-0.0-0.0-0.20.2-0.2-0.0-0.10.4-0.1
Stereotopy head waving duration, day 70.10.10.50.50.5-0.40.30.2-0.1-0.7-0.50.40.30.2-0.3-0.30.3-0.20.2-0.40.2-0.00.2
Locomotion velocity, session 80.70.91.81.10.6-1.31.31.1-1.30.50.5-1.0-1.3-1.40.20.2-1.10.6-0.60.6-1.10.6-0.9
Locomotion distance, session 81.21.84.41.81.4-2.02.02.1-1.90.51.2-1.1-1.1-1.90.40.4-1.20.6-0.60.8-1.21.1-1.2
Degree of sensitization distance1.31.33.0-1.0-1.10.6-0.6-0.30.01.71.4-1.5-1.5-1.01.31.3-1.31.1-1.01.4-1.11.1-1.0
Degree of sensitization stereotypy0.20.20.5-0.6-0.40.6-0.6-0.70.7-0.5-0.50.30.30.5-0.2-0.20.20.0-0.0-0.20.20.50.2
Conditioned locomotion1.41.63.90.3-0.2-0.80.80.7-1.21.21.2-1.3-1.4-1.32.02.0-1.51.4-1.31.1-1.51.1-1.3
Cocaine response after cond. corrected1.11.22.61.11.1-1.51.51.6-1.60.81.3-1.0-0.8-1.60.80.8-0.90.8-0.70.6-0.90.6-1.0
Cocaine response after cond. not corrected1.61.84.51.51.4-1.91.92.1-1.90.71.6-1.1-0.9-1.91.01.0-1.10.9-0.80.8-1.00.8-1.2
Cocaine response before conditioning0.10.10.30.60.3-0.20.20.5-0.0-0.50.20.10.2-0.1-0.1-0.10.1-0.20.10.00.10.2-0.1
Saline control response3.34.48.2-1.3-2.00.4-0.4-0.3-0.52.92.1-2.6-2.7-1.72.52.5-2.62.3-2.32.4-2.52.4-2.1
Bone: connectivity density0.10.10.40.60.3-0.50.50.4-0.50.1-0.10.20.1-0.1-0.2-0.20.1-0.50.3-0.20.10.30.0
Bone: cortical apparent density0.91.12.80.60.60.2-0.2-0.10.5-1.0-1.01.41.41.0-1.2-1.21.4-1.71.4-1.21.4-0.81.2
Bone: cortical area0.30.40.9-0.4-0.41.0-0.9-0.60.9-0.1-0.50.50.40.7-0.3-0.30.6-0.80.6-0.50.6-0.70.8
Bone: cortical porosity0.20.31.0-0.5-0.70.8-0.8-0.70.60.4-0.50.30.10.70.30.30.20.10.0-0.30.1-1.00.3
Bone: cortical porosity0.30.41.2-0.7-0.91.1-1.1-0.90.90.3-0.60.30.10.80.00.00.30.10.0-0.20.2-0.80.3
Bone: cortical thickness1.42.23.50.10.01.2-1.2-0.91.5-1.3-1.91.71.51.7-1.6-1.61.7-1.91.6-1.61.6-1.81.7
Bone: cortical thickness0.80.92.01.41.4-0.30.30.8-0.1-0.8-1.11.11.10.4-0.2-0.21.1-1.31.2-1.21.0-1.20.9
Bone: cortical tissue density0.60.82.10.50.40.1-0.1-0.20.4-0.8-0.81.21.20.9-1.0-1.01.2-1.51.2-1.01.2-0.61.0
Condit. Reinf. active minus inactive responses0.10.10.4-0.2-0.0-0.20.20.3-0.0-0.40.4-0.20.0-0.3-0.2-0.2-0.20.6-0.60.5-0.30.6-0.5
Condit. Reinf. active-inactive response ratio0.10.10.3-0.00.0-0.20.20.4-0.1-0.20.4-0.20.1-0.30.00.0-0.20.5-0.50.5-0.30.6-0.5
Condit. Reinf. active responses0.10.10.50.10.3-0.30.30.4-0.1-0.70.1-0.10.1-0.2-0.6-0.6-0.10.3-0.30.1-0.10.2-0.3
Condit. Reinf. inactive responses0.00.10.30.10.1-0.10.10.0-0.0-0.0-0.2-0.2-0.3-0.2-0.6-0.6-0.1-0.10.1-0.3-0.1-0.40.1
Incentive salience index mean0.70.82.40.61.1-0.30.30.50.2-1.6-0.81.01.20.4-1.4-1.41.0-0.80.8-0.80.9-0.70.6
Condit. Reinf. lever presses2.33.15.90.61.50.4-0.4-0.01.1-2.4-2.02.12.31.5-2.1-2.12.2-2.02.0-2.02.1-1.81.8
Condit. Reinf. active minus inactive responses0.80.92.4-1.4-1.50.8-0.8-1.00.41.10.7-1.1-1.3-0.30.50.5-1.11.0-1.01.0-1.01.2-0.8
Condit. Reinf. active-inactive response ratio0.70.72.0-1.4-1.40.8-0.9-1.00.60.60.5-0.8-0.70.00.40.4-0.80.9-0.90.9-0.70.9-0.7
Condit. Reinf. active responses0.30.41.3-0.9-0.90.9-0.9-1.20.80.1-0.50.1-0.00.7-0.7-0.70.2-0.40.3-0.20.2-0.10.4
Condit. Reinf. inactive responses1.21.52.90.30.40.5-0.5-0.60.8-0.9-1.51.31.21.2-1.6-1.61.3-1.71.6-1.31.4-1.51.4
Condit. Reinf. lever presses1.21.76.0-2.4-2.51.8-1.8-2.11.40.70.3-0.7-0.80.60.60.6-0.71.0-1.01.2-0.61.1-0.5
Condit. Reinf. lever reinforcers received0.30.41.8-1.1-1.21.0-1.0-1.30.90.2-0.3-0.0-0.20.6-0.5-0.5-0.0-0.10.10.10.00.10.2
Conditioned reinforcement - actives1.61.63.20.90.4-1.11.11.3-1.41.61.4-1.4-1.5-1.81.11.1-1.51.3-0.90.9-1.51.1-1.2
Conditioned reinforcement - inactives2.93.26.90.90.1-1.81.81.7-2.22.42.6-2.0-1.8-2.41.81.8-1.91.5-1.41.4-1.80.9-2.0
Conditioned locomotion0.20.20.91.00.7-0.60.60.5-0.4-0.4-0.40.30.2-0.1-0.4-0.40.2-0.10.2-0.20.0-0.50.3
Patch foraging indifference point 0 sec2.23.58.30.0-0.7-1.41.31.0-1.82.12.9-2.4-2.3-2.31.41.4-2.31.9-1.92.0-2.21.7-2.2
Patch foraging indifference point AUC0.40.51.21.11.0-0.60.60.6-0.2-1.1-0.80.70.60.2-0.7-0.70.6-0.60.6-0.60.5-0.80.4
Delay disc. indifference point, 0s delay1.31.42.7-0.40.01.2-1.2-0.91.5-1.3-1.61.31.31.3-1.0-1.01.3-1.11.0-1.01.2-1.51.2
Delay disc. indifference point, 16s delay1.21.24.21.62.0-0.60.61.2-0.1-1.5-1.31.21.20.2-0.9-0.91.0-1.11.0-1.00.9-1.20.8
Delay disc. indifference point, 2s delay1.71.83.7-0.50.21.7-1.7-0.81.9-1.5-1.91.51.61.6-1.1-1.11.5-1.01.0-1.11.4-1.31.3
Delay disc. indifference point, 24s delay2.62.58.82.53.0-1.41.42.0-0.7-1.7-1.41.41.5-0.1-1.2-1.21.3-1.61.5-1.51.2-1.71.0
Delay disc. indifference point, 4s delay1.01.13.1-0.30.51.5-1.4-0.41.6-1.0-1.81.11.21.0-0.5-0.51.1-0.80.8-0.81.0-0.91.0
Delay disc. indifference point, 8s delay1.01.02.81.61.7-0.50.51.0-0.0-1.4-1.71.21.10.4-0.7-0.71.0-0.91.0-1.00.8-0.80.7
Indifference point function ln k0.71.02.00.1-0.3-0.60.60.6-0.91.41.4-1.4-1.4-1.30.70.7-1.30.9-1.10.9-1.21.0-1.0
Indifference point function log k0.71.02.00.1-0.3-0.60.60.6-0.91.41.4-1.4-1.4-1.30.70.7-1.30.9-1.10.9-1.21.0-1.0
Patch foraging total patch changes 0 sec2.03.27.30.2-0.5-1.51.41.1-1.81.92.7-2.3-2.2-2.21.31.3-2.21.8-1.91.9-2.11.7-2.1
Patch foraging total patch changes 12 sec0.10.10.4-0.3-0.60.6-0.6-0.50.50.20.2-0.2-0.20.1-0.2-0.2-0.10.00.1-0.10.00.00.2
Patch foraging total patch changes 18 sec1.11.52.81.00.3-1.51.51.3-1.60.91.7-1.1-1.0-1.51.31.3-1.10.9-1.00.9-1.11.1-1.2
Patch foraging total patch changes 24 sec0.20.20.50.1-0.1-0.40.40.4-0.50.30.7-0.5-0.4-0.50.60.6-0.40.4-0.70.5-0.5-0.1-0.6
Patch foraging total patch changes 6 sec0.50.72.6-0.0-0.1-0.80.70.6-0.80.41.6-1.0-0.7-1.00.40.4-0.90.8-1.00.9-0.81.1-1.0
Patch foraging time to switch 0 sec0.81.34.1-1.5-1.22.0-2.0-1.71.70.1-0.70.70.71.40.00.00.8-0.30.7-0.70.9-0.71.0
Patch foraging water rate 0 sec0.81.34.51.81.7-2.12.11.9-1.7-0.50.6-0.2-0.2-1.1-0.6-0.6-0.3-0.1-0.30.2-0.40.2-0.6
Patch foraging water rate 12 sec1.31.96.52.52.5-2.02.02.0-1.3-1.4-0.30.91.0-0.5-1.1-1.10.8-1.31.0-1.10.7-0.60.4
Patch foraging water rate 18 sec3.14.215.13.63.5-3.43.43.9-2.9-0.01.1-0.7-0.6-2.6-0.8-0.8-0.8-0.3-0.20.1-0.8-0.1-1.0
Patch foraging water rate 24 sec1.82.56.32.01.7-2.52.52.5-2.30.61.5-1.1-1.0-2.20.70.7-1.30.6-1.21.0-1.41.0-1.4
Patch foraging water rate 6 sec1.52.27.22.62.6-2.72.72.7-2.1-0.60.4-0.1-0.1-1.5-0.6-0.6-0.3-0.30.1-0.1-0.3-0.0-0.6
Seeking ratio, delayed vs. immediate footshock0.10.10.3-0.5-0.50.1-0.1-0.4-0.00.50.2-0.4-0.5-0.10.00.0-0.30.4-0.20.2-0.3-0.3-0.2
Distance traveled before self-admin0.40.41.7-0.20.30.6-0.6-0.50.50.3-0.80.60.60.6-0.2-0.20.7-0.90.6-0.50.8-1.30.9
Distance traveled after self-admin0.91.02.50.40.4-0.00.0-0.40.4-1.6-1.31.51.41.3-0.7-0.71.3-1.30.9-0.91.2-1.31.1
Extensor digitorum longus weight0.10.50.9-0.9-0.80.5-0.5-0.40.20.90.7-0.8-0.9-0.40.50.5-0.80.9-0.80.8-0.70.8-0.6
Bone: elastic displacement0.80.91.6-0.3-0.10.8-0.8-0.90.9-0.6-1.30.90.61.0-1.1-1.10.9-1.31.1-1.10.9-1.11.2
Bone: elastic work1.52.05.3-1.7-1.42.3-2.3-2.12.2-0.5-1.31.00.91.8-0.5-0.51.1-0.90.9-0.91.1-1.01.4
Bone: endosteal estimation1.94.27.9-2.6-2.41.4-1.4-1.10.42.52.1-2.1-1.9-0.82.82.8-1.92.4-2.12.4-1.72.4-1.5
Bone: endosteal perimeter1.53.15.4-1.3-1.50.1-0.1-0.0-0.62.12.1-2.1-2.0-1.42.32.3-2.02.1-2.02.3-1.92.2-1.8
Epididymis fat weight1.94.415.6-3.9-3.53.7-3.7-3.42.91.2-0.0-0.8-0.61.31.01.0-0.41.1-1.21.2-0.21.30.4
Delta time in closed arm before/after self-admin0.30.30.90.40.0-0.90.90.4-0.8-0.20.9-0.4-0.4-0.6-0.3-0.3-0.50.6-0.20.2-0.50.7-0.6
Delta time in open arm before/after self-admin0.70.72.6-1.5-1.61.3-1.3-1.30.80.80.2-0.1-0.00.70.80.8-0.00.4-0.50.5-0.00.2-0.0
Diff in mean of infusions in LGA sessions0.70.71.30.61.0-0.20.20.20.1-0.9-0.80.91.00.5-1.1-1.11.0-1.11.0-1.01.0-1.10.9
Delay discount exponential model param1.81.94.4-1.2-1.8-0.20.2-0.7-0.71.82.1-1.7-1.7-0.91.01.0-1.61.5-1.51.5-1.51.6-1.3
Extinction: sum of active levers before priming0.40.40.70.10.0-0.60.60.4-0.80.80.9-0.8-0.8-0.80.40.4-0.80.6-0.50.7-0.70.7-0.7
Active lever presses in extinction session 61.41.32.8-1.0-1.50.6-0.6-0.80.01.71.1-1.5-1.7-0.71.11.1-1.41.3-1.21.2-1.31.1-0.9
Bone: final force0.30.41.8-1.0-0.81.3-1.3-0.81.10.1-0.20.20.30.70.20.20.3-0.00.1-0.00.4-0.30.4
Bone: final moment0.20.31.5-1.0-0.81.2-1.2-0.71.00.2-0.10.20.20.50.00.00.3-0.10.1-0.00.3-0.20.4
Food consumed during 24 hour testing period0.10.20.6-0.50.20.7-0.7-0.10.8-0.4-0.4-0.10.10.0-0.6-0.60.1-0.00.0-0.00.2-0.00.1
Glucose0.81.22.3-1.0-1.40.5-0.5-0.60.11.21.3-1.4-1.4-0.81.21.2-1.30.9-1.11.0-1.21.5-0.9
Heart weight1.11.64.9-2.2-2.11.9-1.9-1.61.21.40.2-0.8-0.70.41.01.0-0.60.9-1.21.1-0.61.1-0.3
Delay discount hyperbolic model param1.71.84.5-0.9-1.5-0.60.5-0.4-1.01.82.1-1.7-1.7-1.01.01.0-1.61.4-1.41.4-1.41.5-1.3
Intermittent access intake day 1-15 change1.11.12.3-0.8-1.20.5-0.5-0.6-0.01.51.3-1.4-1.4-0.80.80.8-1.31.3-1.01.0-1.21.1-0.8
Intermittent access intake escalation1.00.92.2-0.5-1.00.3-0.3-0.3-0.21.51.3-1.3-1.3-0.90.70.7-1.21.3-0.90.9-1.21.0-0.9
Intermittent access intake escalation 21.31.32.6-0.9-1.60.5-0.5-0.5-0.01.61.6-1.5-1.3-0.81.01.0-1.31.4-1.11.1-1.21.4-1.0
Intermitt. access day 1 inactive lever presses0.10.10.40.30.2-0.30.30.3-0.30.50.5-0.2-0.0-0.4-0.6-0.6-0.00.30.4-0.4-0.00.4-0.1
Intermitt. access day 15 inactive lever presses2.62.89.1-0.8-2.0-0.20.2-0.2-1.02.83.0-2.2-2.1-1.61.51.5-1.91.7-1.41.4-1.71.5-1.5
Intermitt. access escalation Index1.41.23.2-1.5-1.80.7-0.7-1.20.31.10.4-1.0-1.3-0.11.21.2-1.21.3-1.31.3-1.21.2-0.9
Intermittent access day 1 total infusions0.20.21.00.20.20.5-0.5-0.40.40.5-1.00.30.00.3-0.2-0.20.2-0.50.6-0.60.2-0.60.6
Intermittent access day 15 total infusions0.40.53.0-0.3-0.70.7-0.7-0.70.21.70.4-0.9-1.1-0.50.40.4-0.80.6-0.30.3-0.70.3-0.2
Intermittent access terminal intake (last 3 days)0.20.31.5-0.2-0.50.8-0.8-0.90.41.2-0.2-0.5-0.8-0.1-0.1-0.1-0.40.20.2-0.3-0.3-0.00.2
Intermittent access total infusions0.30.31.9-0.4-0.70.6-0.6-0.70.21.40.0-0.6-0.9-0.20.50.5-0.60.5-0.30.3-0.60.2-0.1
Intermittent access day 1 locomotion1.41.44.20.50.70.7-0.7-0.60.9-0.8-2.01.41.11.2-1.1-1.11.2-1.41.4-1.41.2-1.71.5
Intermittent access day 15 total locomotion0.10.10.3-0.2-0.50.3-0.3-0.40.10.50.3-0.2-0.20.00.50.5-0.20.1-0.30.3-0.2-0.1-0.1
Intermittent access total locomotion0.50.51.60.50.50.3-0.3-0.30.4-0.4-1.20.90.70.7-0.6-0.60.8-0.90.9-0.90.7-1.30.9
Intermittent access standard deviation0.60.61.60.5-0.2-0.60.60.5-0.81.11.3-1.0-1.0-1.00.60.6-0.90.8-0.50.5-0.90.3-0.7
Left kidney weight0.61.75.1-2.3-2.22.2-2.2-1.71.51.30.3-0.7-0.60.50.90.9-0.51.0-0.81.0-0.50.9-0.3
Right kidney weight0.51.54.8-2.2-2.11.9-1.9-1.61.21.60.4-0.8-0.70.40.91.0-0.60.9-0.81.0-0.51.0-0.3
Cocaine induced anxiety0.60.71.50.6-0.1-0.70.70.8-1.01.20.6-1.0-1.1-1.11.01.0-1.00.6-0.60.6-1.00.5-0.9
Post-drug Anxiety1.11.22.4-1.4-1.60.8-0.8-0.80.21.51.1-1.3-1.2-0.51.21.2-1.11.2-1.11.1-1.01.1-0.8
Baseline Anxiety1.01.14.4-2.1-1.91.3-1.3-1.70.90.61.0-0.7-0.50.40.60.6-0.50.9-0.90.9-0.41.0-0.3
Tail length0.72.13.9-1.5-1.50.5-0.5-0.5-0.01.51.4-1.8-1.8-1.01.81.8-1.72.0-1.71.7-1.61.2-1.3
Length with tail0.93.57.2-2.7-2.62.1-2.1-1.61.22.01.4-1.8-1.7-0.42.02.0-1.62.2-1.91.9-1.51.7-1.2
Length without tail0.51.14.1-1.7-1.72.0-2.0-1.41.51.00.3-0.3-0.30.60.50.5-0.20.5-0.40.4-0.10.7-0.0
Times rat made contact with spout1.11.24.6-2.1-2.11.9-1.9-1.91.50.6-0.2-0.4-0.50.70.30.3-0.40.5-0.50.5-0.30.4-0.0
Lifetime Intake0.30.41.8-0.4-0.60.2-0.2-0.5-0.21.40.4-0.7-0.9-0.40.70.7-0.70.6-0.60.5-0.70.3-0.4
Liver weight, left0.00.00.0-0.2-0.10.1-0.1-0.20.10.00.1-0.1-0.0-0.0-0.1-0.1-0.0-0.20.0-0.10.00.00.0
Liver weight, right0.10.10.20.20.40.4-0.3-0.00.4-0.3-0.30.20.20.1-0.5-0.50.2-0.40.4-0.30.3-0.20.5
Locomotor activity0.10.20.5-0.5-0.70.6-0.6-0.50.40.2-0.1-0.1-0.10.20.60.6-0.10.3-0.20.3-0.1-0.0-0.1
Locomotor testing distance0.00.00.20.40.1-0.40.40.2-0.3-0.2-0.1-0.0-0.1-0.10.00.0-0.1-0.2-0.10.2-0.1-0.1-0.2
Locomotor testing rearing0.20.30.7-0.5-0.80.2-0.2-0.40.1-0.40.4-0.2-0.20.10.80.8-0.30.7-0.60.7-0.40.7-0.5
Locomotion in novel chamber1.92.33.20.60.3-1.51.51.4-1.71.41.7-1.5-1.6-1.81.51.5-1.71.4-1.61.4-1.81.8-1.8
Locomotion in novel chamber post-restriction0.91.12.71.31.3-1.41.41.6-1.3-0.30.8-0.4-0.4-1.01.51.5-0.51.0-0.60.6-0.70.6-1.0
Fecal boli incidents, locomotor time 11.41.63.21.00.8-1.21.21.7-1.41.10.9-1.3-1.3-1.81.21.2-1.31.2-1.21.3-1.40.5-1.4
Change in fecal boli incidents, locomotor task0.10.11.00.1-0.1-0.30.3-0.2-0.1-0.5-0.00.30.10.3-0.1-0.10.1-0.10.2-0.40.11.00.1
Time >=10cm from walls, locomotor time 10.20.21.90.50.5-0.50.50.6-0.5-0.00.4-0.2-0.2-0.50.50.5-0.30.2-0.20.1-0.31.4-0.4
Bouts of movement, locomotor time 10.70.82.81.31.4-1.21.21.7-1.20.70.4-0.6-0.4-1.30.50.5-0.50.3-0.40.3-0.6-0.3-0.7
Total resting periods, locomotor time 11.11.24.01.51.6-1.61.62.0-1.70.90.6-0.8-0.6-1.60.60.6-0.70.4-0.50.4-0.7-0.2-0.9
Rest time, locomotor task time 10.80.91.80.50.7-1.11.01.2-1.20.81.0-1.0-0.7-1.30.90.9-0.90.9-1.00.7-0.90.4-1.0
Distance moved, locomotor task time 13.84.17.61.31.60.1-0.10.10.9-2.2-2.42.32.11.6-2.7-2.72.3-2.52.7-2.42.2-2.22.3
Vertical activity count, locomotor time 10.80.81.9-0.7-0.11.3-1.3-0.81.4-0.9-1.20.90.91.2-0.6-0.60.9-0.80.7-0.60.9-0.21.1
Time >=10cm from walls, locomotor time 20.60.72.0-1.4-1.41.3-1.3-1.31.00.50.3-0.4-0.40.40.70.7-0.30.7-0.60.5-0.30.7-0.1
Bouts of movement, locomotor time 20.20.30.8-0.3-0.20.8-0.8-0.50.8-0.2-0.90.40.20.6-0.2-0.20.3-0.50.1-0.20.3-0.80.5
Total resting periods, locomotor time 20.10.10.6-0.3-0.40.8-0.7-0.50.70.0-0.60.1-0.10.40.10.10.0-0.2-0.10.10.0-0.50.3
Rest time, locomotor task time 20.10.10.30.30.2-0.30.30.4-0.40.50.2-0.5-0.5-0.60.10.1-0.40.0-0.20.1-0.30.1-0.3
Distance moved, locomotor task time 20.91.12.81.01.2-0.50.50.5-0.1-1.2-0.81.21.20.5-1.3-1.31.1-1.11.2-1.21.1-1.71.0
Vertical activity count, locomotor time 20.40.41.2-0.10.30.4-0.4-0.30.6-1.1-0.70.90.90.8-0.3-0.30.8-0.50.5-0.50.7-0.70.8
Light reinforcement 10.91.62.9-0.1-0.4-0.40.40.8-0.81.31.5-1.6-1.5-1.61.01.0-1.61.4-1.71.7-1.61.2-1.7
Light reinforcement 22.33.16.0-0.0-0.8-0.70.70.9-1.21.91.4-2.2-2.4-1.91.71.7-2.42.2-2.42.3-2.51.1-2.3
Bone: marrow area2.04.38.2-2.6-2.41.3-1.3-1.10.32.62.1-2.2-1.9-0.92.92.9-2.02.4-2.12.4-1.82.4-1.6
Bone: maximum diameter0.81.53.5-1.5-1.50.9-0.9-0.60.21.71.4-1.3-1.1-0.61.91.9-1.11.1-1.11.3-1.01.0-0.8
Bone: maximum force0.20.31.2-1.0-0.91.1-1.1-0.50.70.70.3-0.2-0.00.20.60.6-0.00.2-0.30.4-0.00.20.0
Bone: maximum moment0.20.31.1-0.9-0.81.1-1.0-0.50.80.60.2-0.10.10.30.30.30.10.0-0.10.20.10.10.1
Mean time between licks in bursts0.10.20.50.40.3-0.60.60.6-0.6-0.00.1-0.0-0.0-0.30.30.3-0.20.3-0.30.3-0.30.7-0.5
Mean num. licks in bursts0.40.51.5-0.8-1.10.6-0.6-1.00.21.20.3-0.8-1.1-0.20.80.8-0.80.3-0.30.3-0.60.6-0.1
Cd content in liver0.40.41.2-1.1-0.31.0-1.0-0.71.0-0.90.00.50.90.7-0.0-0.00.70.40.1-0.10.70.10.5
Co content in liver0.50.62.51.11.2-0.40.40.60.1-1.6-0.70.80.80.2-0.8-0.80.7-0.60.8-0.80.7-0.60.6
Cu content in liver0.20.30.70.80.7-0.70.70.8-0.70.40.5-0.4-0.3-0.70.40.4-0.40.3-0.10.1-0.3-0.1-0.2
Fe content in liver0.30.41.4-1.0-1.20.7-0.7-0.60.50.60.7-0.3-0.20.20.70.7-0.20.5-0.40.6-0.20.6-0.4
K content in liver3.73.78.01.71.9-0.40.40.50.4-2.2-2.22.32.21.3-2.1-2.12.2-2.12.4-2.12.1-2.81.9
Mg content in liver1.31.43.50.60.50.2-0.2-0.30.6-1.2-1.31.51.51.2-1.2-1.21.5-1.21.4-1.31.4-1.91.2
Mn content in liver1.11.33.31.20.7-1.81.81.5-1.70.30.7-0.8-1.0-1.31.01.0-1.00.8-0.70.8-1.10.6-1.2
Na content in liver3.13.25.10.40.30.8-0.8-1.01.4-2.2-2.22.32.02.1-2.0-2.02.1-2.12.0-1.82.0-2.22.0
Rb content in liver0.60.71.90.30.40.6-0.6-0.10.8-0.8-0.41.11.40.8-0.8-0.81.2-0.90.9-1.01.2-0.91.0
Se content in liver0.91.11.8-0.00.60.6-0.6-0.50.9-1.2-1.31.21.21.0-0.8-0.81.3-1.11.3-1.21.3-1.31.3
Sr content in liver0.50.40.90.60.5-0.70.70.9-0.70.20.5-0.6-0.7-0.90.60.6-0.70.6-0.60.6-0.70.7-0.7
Zn content in liver0.20.20.90.20.60.1-0.10.20.3-1.0-0.80.60.60.4-0.2-0.20.5-0.30.5-0.40.50.00.4
Bone: minimum diameter0.30.51.4-1.1-1.21.0-1.0-0.90.70.50.2-0.4-0.50.20.90.9-0.40.6-0.40.6-0.30.6-0.1
Time in familiar zone, hab. session 11.61.52.6-0.20.50.6-0.6-0.81.0-1.5-1.11.41.51.3-1.5-1.51.5-1.31.3-1.61.5-0.91.5
Time in novel zone, hab. session 11.81.73.7-0.5-1.10.00.00.1-0.51.51.1-1.4-1.5-1.01.91.9-1.51.5-1.51.9-1.51.4-1.5
Total zone transitions, hab. session 10.50.62.31.41.5-1.11.11.1-0.8-0.6-0.50.20.1-0.5-0.6-0.60.2-0.70.7-0.40.3-1.20.2
Total locomotion distance, hab. session 10.81.13.92.01.9-1.71.71.5-1.4-0.1-0.20.10.0-0.8-0.6-0.60.1-0.80.8-0.70.2-1.30.3
Locomotion velocity, hab. session 11.01.54.72.22.2-1.91.81.7-1.4-0.5-0.40.40.3-0.7-0.9-0.90.4-1.01.0-0.90.4-1.40.4
Time in familiar zone, hab. session 20.30.30.70.40.0-0.70.70.5-0.80.70.4-0.4-0.5-0.50.50.5-0.50.5-0.50.3-0.60.7-0.7
Time in novel zone, hab. session 20.30.31.0-1.0-0.91.0-1.0-0.80.80.10.2-0.3-0.20.20.30.3-0.20.3-0.40.5-0.10.00.0
Total zone transitions, hab. session 20.50.71.30.1-0.1-0.40.40.5-0.60.60.7-1.1-1.1-1.00.90.9-1.11.0-1.01.1-1.10.8-1.0
Total locomotion distance, hab. session 22.12.74.20.7-0.0-1.31.31.3-1.61.51.8-1.9-2.0-2.01.61.6-2.01.8-1.81.8-2.01.8-2.0
Locomotion velocity, hab. session 21.62.23.51.20.5-1.61.61.6-1.81.11.5-1.5-1.7-1.91.21.2-1.71.4-1.41.4-1.71.4-1.7
Novel to familiar place preference ratio0.20.20.7-0.7-0.60.2-0.2-0.10.00.50.8-0.3-0.0-0.10.60.6-0.10.5-0.50.8-0.2-0.0-0.5
Novelty place preference0.10.10.5-0.7-0.50.3-0.3-0.20.20.20.6-0.10.20.10.50.50.10.4-0.40.70.0-0.2-0.4
Time in novel zone, NPP test0.40.41.3-1.1-1.00.6-0.6-0.40.40.40.8-0.3-0.00.10.80.8-0.20.7-0.71.0-0.20.1-0.6
Total zone transitions, NPP test0.20.31.21.11.1-0.90.91.1-0.7-0.3-0.1-0.2-0.3-0.7-0.2-0.2-0.3-0.10.10.1-0.3-0.3-0.2
Total locomotion distance, NPP test1.41.93.51.40.9-1.71.71.8-1.80.71.3-1.3-1.4-1.91.01.0-1.51.1-1.11.2-1.51.1-1.4
Locomotion velocity, NPP test1.21.73.81.81.3-1.91.92.0-1.80.41.0-1.0-1.1-1.80.70.7-1.20.7-0.70.8-1.20.8-1.2
Intraocular pressure1.82.54.51.01.2-1.91.92.1-2.11.21.5-1.6-1.3-2.11.71.7-1.51.4-1.41.3-1.41.3-1.6
Delta distance traveled before/after self-admin1.01.15.30.1-0.00.1-0.1-0.50.7-2.3-1.01.61.61.5-0.8-0.81.4-0.90.8-0.91.2-0.10.8
Delta ambulatory time before/after self-admin0.40.43.60.1-0.1-0.10.1-0.20.4-1.9-0.61.11.01.0-0.3-0.30.8-0.30.2-0.30.60.30.3
Parametrial fat weight4.07.826.2-5.1-4.95.0-5.0-5.04.01.3-0.9-0.5-0.82.20.80.8-0.40.8-0.90.9-0.10.90.7
Pavlov. Cond. lever latency3.34.28.3-1.5-2.40.4-0.4-0.7-0.62.92.0-2.5-2.7-1.42.52.5-2.52.5-2.52.2-2.41.6-1.9
Pavlov. Cond. magazine entry latency1.41.84.30.20.40.6-0.6-0.51.1-2.1-1.41.61.61.4-1.7-1.71.6-1.41.4-1.31.5-1.11.3
Pavlov. Cond. change in total contacts4.64.911.11.52.4-0.30.30.70.7-3.3-2.22.72.91.6-2.9-2.92.7-2.52.5-2.42.6-1.52.0
Pavlov. Cond. index score3.94.99.71.01.70.3-0.3-0.01.2-3.1-2.32.82.92.0-2.7-2.72.7-2.62.6-2.42.7-1.92.2
Pavlov. Cond. latency score3.74.710.51.42.1-0.10.10.40.9-3.2-2.22.72.81.7-2.7-2.72.6-2.52.6-2.42.6-1.72.1
Pavlov. Cond. lever contacts3.23.76.60.91.80.2-0.20.11.0-2.6-1.92.32.41.5-2.4-2.42.3-2.42.4-2.22.3-1.42.0
Pavlov. Cond. magazine entry number1.92.43.90.1-0.4-1.01.00.8-1.52.01.6-1.8-1.9-1.71.91.9-1.91.6-1.61.6-1.91.2-1.7
Pavlov. Cond. intertrial magazine entries4.55.48.20.3-0.5-2.02.01.4-2.52.42.6-2.8-2.8-2.71.91.9-2.82.6-2.72.6-2.92.1-2.8
Pavlov. Cond. lever-magazine prob. diff.4.55.610.50.91.70.4-0.4-0.21.4-3.2-2.53.03.12.2-2.9-2.92.9-2.82.8-2.62.9-2.02.4
Pavlov. Cond. response bias2.83.45.80.31.10.8-0.8-0.41.4-2.4-1.92.32.41.8-2.2-2.22.3-2.22.2-2.02.3-1.42.0
Pavlov. Cond. lever latency1.72.38.73.02.5-2.72.72.6-2.2-0.60.00.30.2-1.1-0.8-0.80.1-0.60.6-0.7-0.0-0.5-0.2
Pavlov. Cond. magazine entry latency3.13.55.4-2.1-2.21.0-1.0-1.00.22.11.7-2.2-2.1-1.02.32.3-2.12.1-2.32.2-1.92.2-1.7
Pavlov. Cond. change in total contacts1.72.48.3-2.9-2.52.7-2.8-2.92.30.3-0.50.1-0.01.5-0.1-0.10.20.1-0.30.10.30.70.6
Pavlov. Cond. index score2.22.89.8-3.1-2.82.5-2.6-2.51.81.10.6-0.9-0.90.71.41.4-0.81.3-1.31.2-0.61.3-0.4
Pavlov. Cond. latency score1.61.97.3-2.7-2.32.2-2.2-2.21.70.80.4-0.7-0.60.71.11.1-0.51.0-1.00.9-0.41.0-0.2
Pavlov. Cond. lever contacts1.52.07.5-2.7-2.32.6-2.6-2.32.00.7-0.0-0.3-0.21.00.80.8-0.10.6-0.60.7-0.00.50.1
Pavlov. Cond. magazine entry number1.92.36.12.52.4-1.71.71.7-0.9-1.7-1.01.41.40.1-1.7-1.71.3-1.41.5-1.31.1-1.40.8
Pavlov. Cond. intertrial magazine entries0.81.02.41.41.5-0.90.91.0-0.3-1.5-0.91.11.20.3-1.0-1.01.0-0.60.9-0.80.8-1.00.5
Pavlov. Cond. lever-magazine prob. diff.2.02.69.9-3.1-2.82.7-2.7-2.72.10.90.2-0.6-0.61.01.01.0-0.40.9-0.90.9-0.31.0-0.1
Pavlov. Cond. response bias1.92.68.2-2.9-2.62.3-2.3-2.21.61.50.7-1.2-1.10.31.51.5-1.01.4-1.41.4-0.91.3-0.6
Time in closed arm before self-admin0.40.40.90.40.4-0.50.50.7-0.60.30.6-0.9-0.9-1.00.90.9-0.80.5-0.40.3-0.70.2-0.6
Time in closed arm after self-admin1.21.22.61.00.6-1.51.51.2-1.40.21.3-1.3-1.3-1.60.60.6-1.30.9-0.60.5-1.20.7-1.0
Time in open arm before self-admin0.70.71.8-0.4-0.40.5-0.5-1.00.7-0.6-1.21.21.01.3-1.1-1.11.0-0.80.7-0.61.0-0.10.8
Time in open arm after self-admin1.61.84.4-1.5-1.31.7-1.7-2.11.6-0.1-1.71.41.22.1-0.8-0.81.3-1.00.7-0.51.2-0.81.2
Bone: periosteal estimation0.91.83.9-1.9-1.91.3-1.3-1.00.51.81.2-1.2-1.1-0.32.02.0-1.11.3-1.11.4-0.91.3-0.7
Bone: periosteal perimeter0.61.02.0-0.9-1.10.3-0.3-0.3-0.21.31.1-1.1-1.1-0.61.41.4-1.11.0-1.01.3-1.01.0-0.8
Bone: post-yield work0.20.31.2-0.3-0.5-0.10.10.2-0.41.11.1-0.7-0.5-0.60.60.6-0.50.5-0.60.7-0.50.5-0.6
Progressive ratio test 1 active lever presses0.10.10.4-0.2-0.10.5-0.5-0.60.30.5-0.60.20.00.4-0.1-0.10.2-0.30.5-0.50.2-0.50.4
Progressive ratio test 1 breakpoint0.40.40.9-0.4-0.10.8-0.8-0.90.60.3-0.90.50.30.7-0.4-0.40.5-0.50.7-0.80.5-0.80.7
Progressive ratio test 1 inactive lever presses1.21.33.5-0.4-0.9-0.30.30.2-0.81.91.8-1.4-1.3-1.21.21.2-1.31.3-1.21.2-1.20.6-1.3
Progressive ratio test 2 active lever presses0.10.10.5-0.0-0.20.5-0.5-0.30.30.70.0-0.1-0.1-0.00.10.1-0.1-0.20.1-0.10.0-0.10.3
Progressive ratio test 2 breakpoint0.10.10.4-0.1-0.30.5-0.5-0.40.30.6-0.10.0-0.10.10.10.10.1-0.30.2-0.20.1-0.30.4
Progressive ratio test 2 inactive lever presses2.42.76.1-0.8-1.70.3-0.3-0.2-0.52.52.0-2.0-2.0-1.42.12.1-1.91.7-2.02.0-1.91.1-1.6
Incentive Sensitization - Responses0.50.51.0-0.3-0.7-0.00.00.0-0.30.90.9-0.8-0.8-0.60.90.9-0.80.7-1.01.0-0.80.6-0.8
Incentive Sensitization - Breakpoint0.60.61.1-0.4-0.90.0-0.0-0.1-0.30.91.0-0.9-0.9-0.60.90.9-0.90.8-1.01.0-0.90.7-0.8
Sum of active levers in priming session hrs 5-60.80.72.01.31.0-1.41.41.2-1.40.50.6-0.7-0.8-1.20.10.1-0.70.40.0-0.0-0.70.2-0.6
Progressive ratio1.82.15.11.20.7-1.81.81.6-2.00.71.5-1.0-1.0-1.52.32.3-1.21.5-1.10.9-1.20.8-1.3
Food seeking constrained by brief footshock1.82.24.41.72.1-1.21.20.7-0.5-1.9-1.81.81.50.8-1.0-1.01.6-1.11.8-2.01.4-2.01.3
Seeking ratio, punishment vs. effort3.13.87.0-0.8-0.11.6-1.6-1.72.0-1.8-2.52.01.92.3-2.6-2.62.1-2.01.9-1.92.1-2.02.0
Retroperitoneal fat weight4.414.351.3-7.0-6.07.2-7.1-6.55.91.0-1.20.00.13.50.80.80.40.9-0.80.80.71.21.4
Reaction time number correct2.02.94.60.80.7-1.61.62.0-1.80.81.6-1.6-1.5-2.01.81.8-1.72.1-2.12.0-1.91.3-2.1
Reaction time mean minus median0.81.04.2-2.1-2.01.4-1.4-1.91.00.70.4-0.6-0.60.50.60.6-0.40.7-0.70.5-0.30.8-0.1
Reaction time mean minus median AUC1.11.44.4-2.1-2.11.2-1.3-1.60.80.80.6-1.0-1.00.10.80.8-0.91.2-1.31.1-0.81.5-0.7
Reaction time num false alarms0.71.04.42.11.8-1.51.51.8-1.1-0.5-0.0-0.1-0.3-1.1-0.7-0.7-0.2-0.50.5-0.3-0.2-0.4-0.1
Reaction time num false alarms AUC0.60.83.51.91.6-1.41.41.6-1.0-0.60.0-0.0-0.1-0.9-0.6-0.6-0.1-0.50.5-0.2-0.1-0.6-0.1
Reaction time trials correct on left2.02.94.60.80.7-1.61.62.0-1.80.81.6-1.6-1.5-2.01.81.8-1.72.1-2.12.0-1.91.3-2.1
Reaction time trials on left2.23.15.10.70.6-1.61.61.9-1.80.91.6-1.7-1.6-2.02.02.0-1.82.2-2.22.1-2.01.5-2.3
Reaction time mean1.31.87.4-2.7-2.42.2-2.2-2.31.61.20.2-0.6-0.60.80.70.7-0.40.7-0.70.6-0.21.00.1
Reaction time mean AUC1.01.45.6-2.4-2.02.0-2.0-2.11.50.9-0.1-0.4-0.40.80.40.4-0.30.4-0.60.4-0.10.80.2
Median of all reaction times1.11.56.1-2.5-2.12.1-2.1-2.11.51.10.0-0.5-0.40.80.60.6-0.30.5-0.50.4-0.10.90.2
Reaction time omissions0.81.13.0-1.6-1.60.6-0.6-0.90.30.71.0-0.8-0.70.00.80.8-0.81.3-1.31.3-0.81.7-0.9
Reaction time false alarm rate0.50.71.71.31.1-0.60.60.6-0.2-0.7-0.50.50.4-0.1-1.3-1.30.5-1.21.2-0.90.6-1.00.7
Reaction time premature initiation rate0.10.10.40.40.1-0.10.10.3-0.20.40.1-0.5-0.6-0.60.30.3-0.50.2-0.10.3-0.4-0.4-0.2
Reaction time premature initiations0.91.22.60.90.5-1.01.01.3-1.20.80.9-1.3-1.2-1.61.11.1-1.31.1-1.01.1-1.30.1-1.2
Std. dev. reaction times0.91.35.3-2.3-2.11.7-1.7-2.01.20.80.1-0.5-0.50.70.40.4-0.40.6-0.70.5-0.20.90.0
Reaction time trials completed2.23.15.10.70.6-1.61.61.9-1.80.91.6-1.7-1.6-2.02.02.0-1.82.2-2.22.1-2.01.5-2.3
Reaction time trials AUC2.84.06.40.60.4-1.71.72.0-2.01.22.0-2.0-1.9-2.32.22.2-2.12.5-2.52.4-2.31.8-2.5
Run reversals in cocaine runway, females1.11.03.9-2.0-1.71.7-1.7-1.71.40.1-0.40.0-0.00.90.70.7-0.10.7-0.50.4-0.00.70.1
Run reversals in cocaine runway, males2.72.65.1-1.1-0.82.1-2.1-1.82.3-1.2-1.41.51.52.0-1.5-1.51.7-1.41.5-1.41.7-1.11.8
Latency to leave start box in cocaine runway1.31.42.50.8-0.0-1.21.20.9-1.51.20.9-1.2-1.5-1.21.61.6-1.40.7-1.21.2-1.41.2-1.1
Latency to leave start box in cocaine runway, F1.71.84.60.1-0.8-0.30.30.5-0.91.91.5-1.6-1.6-1.32.22.2-1.61.0-1.41.5-1.51.5-1.1
Latency to leave start box in cocaine runway, M0.60.51.61.11.0-1.31.20.5-0.8-0.9-1.10.60.10.2-0.5-0.50.2-0.60.5-0.60.1-0.40.2
Std. dev. time between licks in bursts0.20.31.11.01.0-0.90.91.0-0.6-0.5-0.10.20.3-0.3-0.1-0.10.1-0.00.0-0.10.00.2-0.2
Total sessions with >9 infusions0.30.31.2-1.1-0.80.9-0.9-1.10.70.2-0.2-0.1-0.20.50.40.4-0.10.4-0.40.4-0.10.2-0.1
Short access day 1 total inactive lever presses3.84.38.80.4-0.7-1.31.31.3-1.82.13.0-2.5-2.4-2.51.91.9-2.52.6-2.12.1-2.52.0-2.5
Short access day 10 total inactive lever presses1.21.33.1-0.9-1.30.1-0.1-0.1-0.31.21.6-1.3-1.2-0.80.80.8-1.31.8-1.31.3-1.31.6-1.3
Short access day 1 total infusions1.11.22.00.3-0.1-0.90.90.8-1.11.01.4-1.2-1.2-1.21.41.4-1.21.1-1.21.2-1.20.5-1.2
Short access day 10 total infusions0.10.10.4-0.0-0.20.2-0.2-0.3-0.00.6-0.0-0.3-0.5-0.20.40.4-0.40.5-0.20.2-0.50.0-0.3
Short access total infusions0.20.20.5-0.6-0.70.2-0.2-0.60.00.60.4-0.4-0.5-0.00.70.7-0.50.5-0.60.5-0.50.3-0.3
Short access day 1 locomotion0.20.20.9-0.6-1.00.4-0.4-0.70.3-0.10.2-0.2-0.20.20.60.6-0.20.4-0.50.5-0.30.1-0.2
Short access day 10 total locomotion0.30.31.00.91.0-0.30.30.7-0.1-0.5-0.70.40.4-0.2-0.5-0.50.4-0.30.5-0.50.3-0.90.3
Short access total locomotion0.80.82.40.10.30.5-0.5-0.60.8-1.2-1.51.21.01.1-0.7-0.71.0-0.80.8-0.80.9-1.00.9
One hour access (0.3 mA shock)0.30.31.20.70.6-1.01.00.5-1.10.70.3-0.4-0.5-0.70.40.4-0.50.4-0.10.1-0.50.1-0.4
Compulsive drug intake1.01.14.40.80.7-2.12.01.2-1.8-0.11.3-0.6-0.4-1.10.30.3-0.60.8-0.30.3-0.70.6-1.0
One hour access (shock baseline)0.20.21.0-0.3-0.51.0-1.0-0.70.70.7-0.40.20.10.4-0.0-0.00.2-0.30.3-0.30.3-0.40.5
Social response proportion1.51.65.9-2.3-2.12.1-2.1-2.41.7-0.1-0.60.2-0.01.40.80.80.10.5-0.20.20.20.40.5
Social responses0.10.20.8-0.4-0.30.9-0.9-0.50.70.0-0.40.10.10.30.30.30.10.10.00.00.1-0.10.3
Social time0.60.83.3-1.2-1.01.8-1.8-1.31.7-0.4-1.00.50.41.1-0.2-0.20.4-0.30.00.20.40.20.5
Soleus weight0.10.20.7-0.6-0.50.2-0.2-0.10.10.20.6-0.5-0.4-0.30.40.4-0.50.7-0.60.8-0.50.8-0.6
Bone: stiffness0.30.51.6-0.5-0.70.4-0.40.10.01.00.8-0.6-0.5-0.41.31.3-0.50.8-0.80.9-0.60.6-0.6
Tibialis anterior weight0.31.04.5-2.1-1.81.7-1.7-1.81.40.20.2-0.10.00.80.00.0-0.00.4-0.40.60.10.50.1
Time to tail flick, vehicle, before self-admin3.13.25.8-1.7-2.10.2-0.2-0.7-0.52.32.2-2.3-2.4-1.31.61.6-2.21.9-1.92.1-2.02.2-1.7
Time to tail flick, vehicle, after self-admin0.50.51.91.11.4-0.20.30.9-0.0-0.3-0.40.20.4-0.4-1.0-1.00.4-0.90.9-0.90.6-0.80.7
Time to tail flick, test, before self-admin0.30.31.20.71.1-0.50.50.4-0.40.2-0.20.00.0-0.4-0.9-0.90.1-0.30.6-0.70.1-0.10.3
Time to tail flick, test, after self-admin4.44.69.40.1-0.6-1.21.21.3-2.03.12.8-2.6-2.4-2.52.22.2-2.52.2-2.12.2-2.42.4-2.3
Delta time to tail flick, vehicle, before/after SA1.21.13.91.72.0-0.60.61.5-0.2-0.7-0.60.91.2-0.1-1.0-1.01.0-1.11.1-1.31.0-1.40.9
Delta time to tail flick, test, before/after SA2.72.44.4-0.3-0.9-0.60.60.7-1.22.11.9-1.7-1.6-1.52.02.0-1.71.6-1.71.8-1.71.7-1.7
Tibia length0.82.28.0-2.4-2.22.8-2.8-2.72.40.6-0.80.1-0.11.4-0.6-0.60.3-0.30.4-0.20.5-0.01.0
Ambulatory time before self-admin0.30.30.9-0.50.00.8-0.8-0.70.60.4-0.50.30.40.60.10.10.5-0.70.4-0.30.6-1.00.7
Ambulatory time after self-admin0.90.92.60.30.50.1-0.1-0.30.5-1.6-1.21.51.51.3-0.5-0.51.3-1.20.8-0.81.2-1.11.0
Bone: tissue strength0.70.71.8-1.3-1.01.3-1.3-1.31.3-0.5-0.40.40.51.0-0.6-0.60.5-0.30.2-0.20.6-0.20.6
Total heroin consumption2.22.54.10.4-0.1-1.31.31.0-1.61.61.6-1.8-2.0-1.81.51.5-2.01.7-1.71.7-2.01.7-1.8
Bone: trabecular number0.10.10.50.70.5-0.50.50.5-0.4-0.3-0.10.30.3-0.00.00.00.2-0.40.3-0.20.20.30.1
Bone: trabecular spacing0.60.82.3-1.3-1.11.5-1.5-1.51.20.5-0.50.40.41.0-0.3-0.30.6-0.50.5-0.40.7-0.80.9
Bone: trabecular thickness0.00.00.10.40.3-0.10.10.30.0-0.3-0.10.10.1-0.1-0.2-0.20.1-0.30.1-0.20.00.10.0
Bone: trabecular tissue density0.91.32.5-0.6-0.41.3-1.3-1.11.4-0.9-1.01.31.41.6-0.4-0.41.4-0.90.9-1.11.4-1.11.2
Water consumed over 24 hours1.01.22.3-0.6-0.90.1-0.10.1-0.31.41.2-1.5-1.5-1.11.11.1-1.41.3-1.31.3-1.31.1-1.2
Number of responses in last shaping day1.01.03.90.2-0.3-0.80.80.8-1.11.32.0-1.2-0.9-1.31.11.1-1.00.7-1.01.0-0.90.2-0.9