Best TWAS P=2.102194e-07 · Best GWAS P=1.389725e-08 conditioned to 0.02150025
# | Tissue | Gene | Modality | RNA phenotype | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | BLA | Eif4e | gene expression | ENSRNOG00000052343 | 0.11 | 0.04 | lasso | 6 | 0.04 | 0.0029 | -5.2 | 5.2 | 2.1e-07 | -0.9 | 0.34 | 0.54 | TRUE |
h2: Heritability estimate for the given transcriptomic model. PP3: Posterior probability of two distinct causal variants. PP4: Posterior probability of a single shared causal variant. joint: Whether the RNA phenotype is in the joint model.