Hub : Genes

Fhip2a

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 NAcc isoform ratio NM_001400898.1 0.03 0.03 1.1e-03 0.02 0.02 0.03 0.02 3.3e-04 2.3e-04 9.8e-05 1.3e-04
2 NAcc alternative TSS NM_001400898.1 0.04 0.03 2.3e-04 0.02 0.02 0.03 0.03 1.7e-04 4.1e-04 5.2e-05 4.6e-05
3 NAcc alternative TSS XM_039101457.2 0.04 0.03 1.1e-04 0.03 0.02 0.03 0.03 7.8e-05 1.7e-04 2.7e-05 2.6e-05
4 NAcc isoform ratio XM_039101457.2 0.05 0.04 6.0e-06 0.03 0.04 0.04 0.04 1.4e-05 3.5e-06 5.0e-07 6.8e-07
5 BLA intron excision ratio chr1_266430137_266432655 0.1 0.08 6.9e-03 -0 -0 0 0 4.3e-01 4.1e-01 3.4e-01 2.7e-01
6 OFC alternative TSS NM_001400898.1 0.32 0.23 5.2e-03 0.07 0 0.05 -0.01 7.8e-03 2.7e-01 2.2e-02 6.8e-01
7 OFC alternative TSS XM_039101457.2 0.27 0.23 7.3e-03 0.07 0 0.04 -0.01 1.2e-02 3.0e-01 4.2e-02 6.9e-01
8 PL isoform ratio NM_001400898.1 0.07 0.04 1.3e-07 0.06 0.04 0.05 0.05 1.9e-07 1.7e-05 5.8e-06 3.0e-06
9 PL alternative TSS XM_039101457.2 0.07 0.04 8.0e-09 0.06 0.06 0.06 0.05 2.8e-07 9.0e-07 7.5e-07 1.5e-06
10 PL alternative TSS NM_001400898.1 0.08 0.05 1.8e-09 0.07 0.07 0.06 0.06 5.5e-08 9.3e-08 1.3e-07 2.5e-07
11 Brain gene expression Fhip2a 0.06 0.04 4.1e-07 0.09 0.08 0.08 0.08 1.7e-08 7.9e-08 5.8e-08 3.2e-08
12 BLA gene expression Fhip2a 0.16 0.1 2.2e-06 0.05 0.08 0.08 0.07 1.3e-03 7.5e-05 5.4e-05 9.9e-05
13 PL gene expression Fhip2a 0.1 0.05 3.9e-12 0.07 0.09 0.09 0.09 6.0e-08 2.9e-10 7.3e-10 1.2e-09
14 IC gene expression Fhip2a 0.28 0.14 4.3e-09 0.12 0.17 0.15 0.18 7.2e-06 1.3e-07 5.3e-07 3.1e-08
15 Liver gene expression Fhip2a 0.04 0.03 1.8e-05 0.03 0.03 0.02 0.03 2.0e-04 1.8e-04 3.0e-03 3.7e-04
16 NAcc gene expression Fhip2a 0.09 0.05 1.6e-09 0.04 0.06 0.05 0.05 5.5e-07 7.2e-09 3.4e-08 1.2e-08
17 PL isoform ratio XM_039101457.2 0.07 0.04 5.0e-08 0.06 0.05 0.06 0.05 4.8e-07 5.3e-06 3.0e-07 5.4e-06
18 LHb isoform ratio NM_001400898.1 0.21 0.16 8.5e-03 0.03 0.07 0.04 0.03 7.4e-02 9.0e-03 4.7e-02 7.1e-02
19 Adipose alternative TSS XM_039101457.2 0.03 0.02 1.3e-03 0.02 0.02 0.01 0.02 1.3e-03 3.0e-03 6.9e-03 2.3e-03
20 Adipose isoform ratio XM_039101457.2 0.04 0.03 4.3e-04 0.03 0.03 0.03 0.03 3.9e-04 7.0e-04 7.1e-04 6.2e-04
21 Adipose alternative TSS NM_001400898.1 0.03 0.02 1.3e-03 0.02 0.02 0.02 0.02 1.3e-03 2.8e-03 6.5e-03 2.2e-03
22 pVTA gene expression Fhip2a 0.05 0.03 6.9e-05 0.06 0.05 0.04 0.05 2.0e-05 5.3e-05 3.4e-04 5.1e-05
23 Brain isoform ratio XR_005499772.2 0.03 0.02 9.1e-03 0.01 0.01 0.01 0 8.7e-02 7.6e-02 8.6e-02 1.5e-01
24 Adipose mRNA stability Fhip2a 0.14 0.09 5.8e-11 0.07 0.07 0.09 0.08 1.5e-08 2.0e-08 7.8e-10 7.6e-09

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24
Bone: apparent density1.11.95.6-2.4-2.02.02.41.8-1.31.3-1.31.3-1.3-0.9-0.6-0.5-0.8-0.4-0.91.3-1.8-0.8-0.80.60.7-1.11.7
Area under the delay curve1.41.74.0-1.4-1.11.01.30.3-1.81.8-1.81.8-1.8-1.8-0.5-1.3-1.2-1.1-0.72.0-1.10.90.9-0.9-0.50.4-1.0
BMI with tail7.726.643.1-6.4-6.66.56.25.8-6.16.1-6.06.0-6.0-5.8-5.5-5.2-5.5-5.0-5.35.1-3.53.13.1-3.1-3.11.9-2.2
BMI without tail5.316.325.3-4.9-5.05.04.64.6-4.54.5-4.54.5-4.5-4.6-4.6-4.2-4.5-4.1-4.23.6-2.42.92.9-3.0-2.82.0-2.1
Body weight6.428.152.4-7.2-7.07.07.06.5-6.26.2-6.26.2-6.2-5.6-5.5-5.0-5.4-4.8-5.34.9-4.32.42.4-2.4-2.61.1-1.6
Weight adjusted by age6.09.212.6-3.0-3.53.52.83.5-3.23.2-3.43.4-3.4-3.4-3.4-3.5-3.2-3.4-3.52.4-1.42.52.5-2.5-2.72.2-1.7
Bone surface0.61.13.1-1.8-1.71.61.71.3-1.11.1-1.11.1-1.1-0.7-1.0-0.6-0.7-0.5-0.81.0-1.1-0.3-0.30.10.1-0.51.1
Bone volume1.83.27.8-2.8-2.62.62.72.3-2.02.0-2.02.0-2.0-1.5-1.9-1.5-1.6-1.4-1.61.7-1.80.30.3-0.5-0.5-0.20.8
Breakpoint value in progressive ratio session0.40.51.4-0.8-0.50.50.70.3-1.01.0-1.01.0-1.0-0.9-0.6-0.8-0.7-0.5-0.30.7-1.20.20.2-0.1-0.3-0.10.1
Number of licking bursts0.20.41.4-0.60.00.00.60.0-0.20.2-0.10.1-0.10.10.50.30.30.50.40.0-1.0-1.0-1.00.91.0-1.20.9
Context. condit. distance diff. score1.21.54.01.51.5-1.5-1.5-2.01.2-1.21.2-1.21.21.51.31.21.21.31.4-0.91.0-0.8-0.80.80.8-0.50.2
Locomotion velocity, session 10.10.10.80.40.2-0.2-0.30.10.4-0.40.4-0.40.40.40.00.40.10.30.0-0.70.9-0.2-0.20.10.10.1-0.3
Locomotion distance, session 10.20.32.40.4-0.10.1-0.40.50.1-0.10.1-0.10.1-0.2-0.5-0.1-0.5-0.3-0.7-0.11.60.40.4-0.6-0.50.9-0.7
Locomotion velocity, session 20.60.73.80.80.1-0.1-0.9-0.11.1-1.11.0-1.01.00.8-0.20.4-0.10.0-0.2-1.62.00.50.5-0.5-0.41.0-1.2
Locomotion distance, session 20.71.02.5-0.7-1.31.30.71.4-0.60.6-0.60.6-0.6-0.7-1.5-0.7-1.4-0.9-1.6-0.01.40.80.8-0.8-0.71.2-1.3
Locomotion velocity, session 30.20.22.00.60.3-0.2-0.6-0.20.4-0.40.5-0.50.50.7-0.10.4-0.20.2-0.2-0.21.40.20.2-0.20.10.6-0.3
Locomotion distance, session 30.40.43.60.80.3-0.3-0.8-0.40.5-0.50.5-0.50.50.7-0.20.4-0.30.2-0.2-0.61.90.20.2-0.2-0.00.8-0.8
Stereotopy head waving bouts, day 30.10.21.3-0.3-0.40.50.40.50.3-0.30.3-0.30.30.10.00.30.40.20.1-0.0-0.4-0.2-0.20.20.3-0.41.1
Stereotopy head waving duration, day 30.20.32.4-0.2-0.10.10.30.20.3-0.30.3-0.30.30.20.30.30.70.30.50.3-1.0-0.4-0.40.40.4-0.71.6
Locomotion velocity, session 70.70.82.1-0.6-0.60.60.60.4-1.11.1-1.01.0-1.0-1.2-1.0-1.0-0.9-0.9-0.71.5-0.50.90.9-0.9-0.90.7-0.4
Locomotion distance, session 70.10.20.4-0.0-0.20.2-0.0-0.4-0.30.3-0.30.3-0.3-0.3-0.6-0.4-0.5-0.3-0.10.60.20.60.6-0.5-0.50.5-0.5
Stereotopy head waving bouts, day 70.10.10.3-0.2-0.30.40.20.3-0.40.4-0.40.4-0.4-0.2-0.5-0.4-0.4-0.4-0.40.30.10.50.5-0.5-0.40.4-0.4
Stereotopy head waving duration, day 71.01.21.9-1.1-1.11.11.11.3-1.41.4-1.41.4-1.4-1.2-1.0-1.2-1.0-1.1-1.11.4-0.70.80.8-0.8-0.80.5-0.3
Locomotion velocity, session 82.42.94.41.71.7-1.7-1.7-1.81.8-1.81.8-1.81.82.11.72.01.62.01.7-1.41.5-1.7-1.71.71.7-1.10.7
Locomotion distance, session 81.62.35.51.81.5-1.5-1.8-1.61.8-1.81.8-1.81.81.81.31.81.21.61.1-1.72.3-1.0-1.01.01.2-0.30.1
Degree of sensitization distance0.20.22.7-0.30.2-0.30.3-0.7-0.20.2-0.20.2-0.2-0.50.3-0.20.40.10.80.5-1.6-0.1-0.10.1-0.1-0.60.6
Degree of sensitization stereotypy0.20.20.3-0.3-0.30.30.30.3-0.50.5-0.50.5-0.5-0.5-0.4-0.5-0.4-0.5-0.40.4-0.20.50.5-0.5-0.50.4-0.3
Conditioned locomotion0.10.10.60.50.2-0.2-0.6-0.30.2-0.20.2-0.20.2-0.2-0.0-0.30.1-0.30.1-0.00.10.50.5-0.6-0.80.6-0.4
Cocaine response after cond. corrected1.11.35.51.71.0-1.0-1.8-1.31.2-1.21.2-1.21.21.30.20.60.30.40.4-1.42.30.50.5-0.5-0.51.2-1.2
Cocaine response after cond. not corrected1.41.74.31.91.4-1.4-1.9-1.61.6-1.61.6-1.61.61.50.71.00.80.80.9-1.82.10.20.2-0.1-0.10.8-0.7
Cocaine response before conditioning0.60.81.70.10.7-0.60.0-0.60.8-0.80.8-0.80.80.31.20.81.10.91.2-0.6-1.1-0.9-0.90.91.0-1.21.3
Saline control response0.30.41.20.70.2-0.2-0.70.10.5-0.50.5-0.50.50.2-0.5-0.20.1-0.4-0.2-0.60.70.90.9-1.0-1.01.1-0.4
Bone: connectivity density0.30.52.7-0.9-0.70.70.90.4-0.30.3-0.30.3-0.3-0.00.20.30.10.40.00.5-0.6-1.0-1.00.91.0-1.01.6
Bone: cortical apparent density0.91.27.71.70.9-0.9-1.8-0.80.9-0.90.9-0.90.91.1-0.10.40.10.1-0.2-0.72.80.80.8-0.7-0.71.6-1.3
Bone: cortical area6.59.918.8-4.2-4.34.34.14.2-3.23.2-3.23.2-3.2-3.3-3.7-3.2-3.0-3.2-3.22.8-2.91.91.9-2.1-2.01.00.0
Bone: cortical porosity0.60.61.30.30.4-0.4-0.3-0.20.8-0.80.8-0.80.80.51.11.01.00.90.7-0.5-0.1-1.1-1.11.01.1-1.00.8
Bone: cortical porosity0.60.72.6-0.20.0-0.00.30.20.5-0.50.5-0.50.50.31.00.90.90.90.7-0.2-0.7-1.3-1.31.21.3-1.41.6
Bone: cortical thickness2.84.69.6-2.7-2.93.02.73.1-2.02.0-2.02.0-2.0-2.0-2.7-2.1-2.3-2.3-2.41.6-1.41.61.6-1.8-1.71.1-0.2
Bone: cortical thickness1.41.73.9-1.2-1.51.51.21.6-1.21.2-1.11.1-1.1-1.0-2.0-1.4-1.5-1.6-1.50.9-0.41.41.4-1.4-1.41.2-0.7
Bone: cortical tissue density1.01.38.31.91.1-1.1-2.0-1.01.0-1.01.0-1.01.01.30.20.60.20.30.0-0.92.90.60.6-0.5-0.51.4-1.2
Condit. Reinf. active minus inactive responses1.51.73.20.70.6-0.6-0.5-0.31.4-1.41.4-1.41.41.81.01.80.81.50.6-1.51.4-1.7-1.71.81.8-1.10.9
Condit. Reinf. active-inactive response ratio1.11.12.00.60.7-0.7-0.5-0.41.2-1.21.2-1.21.21.31.21.40.91.20.7-1.20.7-1.3-1.31.41.4-1.00.6
Condit. Reinf. active responses0.70.92.6-0.6-0.60.70.81.20.5-0.50.5-0.50.51.10.11.1-0.00.8-0.4-1.00.8-1.6-1.61.61.6-1.11.0
Condit. Reinf. inactive responses0.80.94.3-1.5-1.41.61.72.1-0.40.4-0.50.5-0.50.1-1.00.1-0.7-0.1-1.2-0.0-0.1-0.9-0.90.90.8-0.70.8
Incentive salience index mean1.51.94.20.80.6-0.6-0.7-0.31.5-1.51.5-1.51.52.00.91.90.81.50.5-1.81.9-1.7-1.71.71.8-0.90.6
Condit. Reinf. lever presses0.60.82.70.40.2-0.2-0.3-0.00.9-0.90.9-0.90.91.50.41.30.21.00.1-1.21.7-1.2-1.21.21.3-0.50.2
Condit. Reinf. active minus inactive responses1.11.55.2-2.0-1.51.62.11.7-1.11.1-1.11.1-1.1-1.1-0.7-0.6-0.5-0.6-0.61.2-2.3-0.4-0.40.30.4-1.01.4
Condit. Reinf. active-inactive response ratio0.40.52.7-1.0-0.70.71.10.7-0.70.7-0.70.7-0.7-0.7-0.2-0.5-0.2-0.4-0.30.9-1.6-0.0-0.0-0.00.0-0.50.8
Condit. Reinf. active responses2.02.87.7-2.6-2.02.12.82.3-1.81.8-1.81.8-1.8-1.9-1.2-1.2-1.2-1.1-1.22.0-2.5-0.1-0.10.00.1-0.91.1
Condit. Reinf. inactive responses0.71.02.8-1.5-1.21.31.71.4-1.11.1-1.01.0-1.0-1.2-0.8-0.6-0.8-0.6-0.81.1-1.2-0.2-0.20.10.2-0.50.5
Condit. Reinf. lever presses0.60.82.1-1.3-0.90.91.31.0-1.01.0-1.11.1-1.1-1.4-0.6-0.8-0.7-0.7-0.61.0-1.40.20.2-0.3-0.3-0.20.0
Condit. Reinf. lever reinforcers received1.31.85.2-2.1-1.61.72.31.9-1.41.4-1.41.4-1.4-1.5-0.9-0.9-0.9-0.8-1.01.6-2.2-0.2-0.20.10.1-0.81.0
Conditioned reinforcement - actives0.30.62.10.3-0.30.3-0.40.4-0.10.1-0.00.0-0.0-0.2-0.6-0.5-0.8-0.8-0.7-0.21.11.21.2-1.2-1.11.5-1.4
Conditioned reinforcement - inactives0.40.61.0-0.8-0.90.90.70.8-0.90.9-0.80.8-0.8-1.0-0.6-0.8-1.0-0.8-0.80.1-0.30.60.6-0.5-0.50.5-0.9
Conditioned locomotion0.50.62.30.6-0.10.1-0.70.30.0-0.00.1-0.10.1-0.0-0.6-0.4-0.7-0.7-0.8-0.61.51.01.0-1.0-1.11.5-1.4
Patch foraging indifference point 0 sec3.46.29.2-2.9-2.82.82.83.0-2.92.9-2.92.9-2.9-2.8-2.8-2.6-2.8-2.6-2.51.7-1.81.81.8-1.8-1.71.2-1.4
Patch foraging indifference point AUC0.60.92.4-0.9-0.60.70.90.7-1.11.1-1.11.1-1.1-1.0-0.7-1.1-0.5-1.0-0.51.3-1.51.01.0-0.9-0.90.30.2
Delay disc. indifference point, 0s delay0.91.01.6-0.6-0.80.80.50.2-1.21.2-1.11.1-1.1-1.1-1.0-1.2-1.1-1.1-0.70.9-0.41.21.2-1.2-0.90.9-1.1
Delay disc. indifference point, 16s delay0.50.61.4-1.0-0.60.50.9-0.1-1.21.2-1.11.1-1.1-1.2-0.0-0.6-0.7-0.4-0.21.1-0.80.20.2-0.20.0-0.2-0.6
Delay disc. indifference point, 2s delay0.30.31.80.30.4-0.5-0.5-1.1-0.50.5-0.50.5-0.5-0.50.2-0.4-0.4-0.20.20.60.40.60.6-0.6-0.30.5-1.4
Delay disc. indifference point, 24s delay0.50.61.8-1.3-0.70.61.30.2-1.01.0-0.90.9-0.9-1.10.6-0.4-0.3-0.20.11.1-1.40.10.1-0.10.4-0.60.1
Delay disc. indifference point, 4s delay0.20.21.30.10.3-0.4-0.1-0.8-0.60.6-0.60.6-0.6-0.60.2-0.5-0.3-0.20.21.1-0.20.40.4-0.4-0.20.2-0.7
Delay disc. indifference point, 8s delay6.17.111.6-3.0-2.92.82.82.3-3.33.3-3.43.4-3.4-3.2-2.2-2.9-2.8-2.7-2.42.9-1.72.12.1-2.1-1.71.4-1.5
Indifference point function ln k0.30.51.60.40.2-0.2-0.4-0.00.9-0.90.9-0.90.90.80.60.90.50.70.4-1.30.7-0.7-0.70.80.8-0.40.5
Indifference point function log k0.30.51.60.40.2-0.2-0.4-0.00.9-0.90.9-0.90.90.80.60.90.50.70.4-1.30.7-0.7-0.70.80.8-0.40.5
Patch foraging total patch changes 0 sec3.46.59.0-3.0-2.82.82.93.0-2.92.9-2.92.9-2.9-2.9-2.8-2.7-2.8-2.7-2.51.9-2.01.91.9-1.9-1.81.2-1.4
Patch foraging total patch changes 12 sec2.22.94.7-1.9-1.61.61.91.4-2.22.2-2.22.2-2.2-2.2-1.6-1.9-1.5-1.7-1.32.1-1.81.21.2-1.3-1.20.6-0.6
Patch foraging total patch changes 18 sec3.75.69.2-2.9-2.52.52.82.6-2.82.8-2.82.8-2.8-2.8-2.2-2.6-2.0-2.4-1.92.7-3.01.71.7-1.7-1.60.6-0.3
Patch foraging total patch changes 24 sec3.15.39.1-2.5-2.12.12.52.1-2.82.8-2.82.8-2.8-3.0-2.0-2.7-2.1-2.4-1.92.7-2.61.81.8-1.8-1.70.8-0.7
Patch foraging total patch changes 6 sec5.38.011.7-3.4-3.23.23.33.3-3.23.2-3.23.2-3.2-3.0-3.1-3.0-2.8-3.0-2.62.7-2.72.22.2-2.1-2.01.1-0.7
Patch foraging time to switch 0 sec0.30.52.21.00.8-0.9-1.0-1.50.6-0.60.7-0.70.70.60.80.70.40.80.7-0.31.0-0.5-0.50.50.5-0.1-0.6
Patch foraging water rate 0 sec0.40.92.6-1.2-1.21.31.31.6-0.90.9-1.01.0-1.0-0.9-1.3-0.9-0.9-1.0-1.00.5-1.00.60.6-0.6-0.70.20.3
Patch foraging water rate 12 sec0.92.04.8-2.1-1.71.72.22.0-1.61.6-1.61.6-1.6-1.6-1.2-1.1-1.2-1.0-1.11.5-2.00.00.0-0.1-0.2-0.50.9
Patch foraging water rate 18 sec0.50.81.8-0.7-1.01.00.71.3-0.70.7-0.70.7-0.7-1.3-1.1-1.0-1.1-1.1-1.20.30.10.90.9-0.9-1.21.0-0.7
Patch foraging water rate 24 sec1.01.42.7-1.1-1.31.31.01.3-1.21.2-1.21.2-1.2-1.3-1.7-1.3-1.4-1.3-1.30.7-0.21.21.2-1.2-1.31.1-0.7
Patch foraging water rate 6 sec0.91.33.1-0.9-1.11.20.91.3-0.90.9-1.01.0-1.0-1.4-1.8-1.3-1.3-1.4-1.10.7-0.51.41.4-1.4-1.51.1-0.3
Seeking ratio, delayed vs. immediate footshock1.41.73.51.41.0-1.0-1.3-1.11.7-1.71.7-1.71.71.80.91.61.21.30.9-1.71.9-0.8-0.80.80.9-0.30.3
Distance traveled before self-admin0.81.15.01.71.0-1.0-1.9-1.00.7-0.70.7-0.70.70.9-0.40.20.1-0.00.0-0.72.20.90.9-0.9-0.71.5-1.3
Distance traveled after self-admin0.70.85.01.30.5-0.5-1.4-0.50.6-0.60.6-0.60.60.8-0.70.1-0.2-0.1-0.3-0.72.20.80.8-0.8-0.71.4-1.4
Extensor digitorum longus weight0.41.43.7-1.6-1.21.21.61.0-1.51.5-1.41.4-1.4-1.4-0.8-1.2-0.8-0.9-0.71.9-1.90.40.4-0.4-0.4-0.20.5
Bone: elastic displacement0.20.20.60.50.7-0.8-0.6-0.50.2-0.20.2-0.20.2-0.20.6-0.30.5-0.20.50.0-0.70.70.7-0.7-0.60.3-0.5
Bone: elastic work0.70.92.3-0.2-0.60.60.10.9-0.60.6-0.60.6-0.6-0.4-1.2-1.0-0.9-1.2-1.00.40.31.41.4-1.5-1.41.4-0.8
Bone: endosteal estimation1.22.65.1-2.3-2.12.12.21.9-1.91.9-1.91.9-1.9-1.5-1.9-1.5-1.5-1.4-1.51.6-1.50.50.5-0.7-0.70.1-0.2
Bone: endosteal perimeter4.810.215.7-3.7-3.93.93.53.6-3.43.4-3.43.4-3.4-3.5-4.0-3.5-3.3-3.4-3.32.7-2.32.52.5-2.6-2.61.6-1.4
Epididymis fat weight7.525.557.3-7.6-6.96.97.36.3-5.85.8-5.85.8-5.8-5.6-4.8-4.6-4.8-4.3-4.64.6-5.31.61.6-1.5-1.7-0.1-0.8
Delta time in closed arm before/after self-admin0.30.31.50.40.1-0.1-0.4-0.20.7-0.70.8-0.80.80.90.00.60.10.40.1-1.11.2-0.2-0.20.10.20.2-0.6
Delta time in open arm before/after self-admin0.90.94.0-1.2-0.80.81.21.0-1.11.1-1.11.1-1.1-1.3-0.2-1.0-0.4-0.7-0.61.0-2.00.10.10.1-0.3-0.40.6
Diff in mean of infusions in LGA sessions0.50.61.60.71.2-1.2-0.6-1.30.2-0.20.2-0.20.20.40.90.70.71.00.90.0-0.0-1.0-1.01.10.7-1.00.6
Delay discount exponential model param1.51.64.01.31.0-0.9-1.3-0.31.8-1.81.8-1.81.81.80.41.31.21.00.7-2.01.0-0.9-0.90.90.5-0.41.0
Extinction: sum of active levers before priming0.20.20.9-0.00.4-0.5-0.0-1.0-0.10.1-0.10.1-0.10.10.80.20.20.40.7-0.2-0.5-0.4-0.40.40.4-0.60.3
Active lever presses in extinction session 60.00.00.20.10.2-0.10.00.2-0.20.2-0.20.2-0.20.10.1-0.0-0.1-0.00.00.3-0.10.00.0-0.10.2-0.10.4
Bone: final force2.84.58.5-2.5-2.92.92.42.9-2.22.2-2.22.2-2.2-1.6-2.9-2.1-2.4-2.2-2.52.1-0.81.41.4-1.6-1.61.2-0.5
Bone: final moment2.74.38.2-2.5-2.82.92.42.8-2.22.2-2.22.2-2.2-1.6-2.7-2.0-2.3-2.1-2.42.0-0.91.31.3-1.5-1.41.1-0.4
Food consumed during 24 hour testing period1.21.62.70.80.9-0.9-0.8-1.11.5-1.51.5-1.51.51.61.31.61.31.51.4-1.60.6-1.2-1.21.31.3-1.01.2
Glucose1.32.14.1-1.7-1.81.81.72.0-1.41.4-1.41.4-1.4-1.6-1.6-1.5-1.3-1.6-1.61.3-1.31.21.2-1.2-1.10.7-0.1
Heart weight1.72.75.6-2.4-2.32.32.32.2-1.91.9-1.91.9-1.9-1.8-1.4-1.5-1.6-1.4-1.71.3-1.40.60.6-0.6-0.60.10.0
Delay discount hyperbolic model param1.21.43.71.10.8-0.7-1.0-0.11.6-1.61.7-1.71.71.60.41.31.11.00.6-1.90.9-0.9-0.90.90.5-0.51.1
Intermittent access intake day 1-15 change1.42.84.0-1.0-1.41.40.91.2-1.91.9-1.91.9-1.9-1.8-1.5-2.0-1.9-2.0-1.81.20.02.02.0-1.9-1.91.9-1.5
Intermittent access intake escalation1.12.23.2-1.0-1.21.20.91.1-1.81.8-1.71.7-1.7-1.7-1.2-1.8-1.7-1.7-1.61.2-0.21.61.6-1.6-1.51.5-1.1
Intermittent access intake escalation 21.51.73.0-0.6-1.01.00.50.9-1.31.3-1.31.3-1.3-1.3-1.1-1.5-1.5-1.6-1.51.00.41.71.7-1.7-1.61.7-1.3
Intermitt. access day 1 inactive lever presses0.52.05.6-2.1-1.61.62.01.3-1.71.7-1.81.8-1.8-1.9-0.5-1.4-1.0-1.1-0.91.5-2.40.30.3-0.2-0.5-0.30.3
Intermitt. access day 15 inactive lever presses0.30.51.3-0.4-0.20.20.40.3-0.90.9-0.80.8-0.8-1.10.0-1.1-0.5-0.9-0.50.7-1.10.90.9-0.7-0.90.5-0.4
Intermitt. access escalation Index0.30.40.90.50.6-0.6-0.5-0.60.8-0.80.7-0.70.70.90.80.70.50.70.6-0.60.5-0.5-0.50.40.5-0.40.3
Intermittent access day 1 total infusions0.30.50.9-0.5-0.80.80.50.7-0.70.7-0.60.6-0.6-0.6-0.8-0.7-1.0-0.8-0.80.20.30.80.8-0.8-0.70.8-0.9
Intermittent access day 15 total infusions1.11.62.8-0.6-0.90.90.50.6-1.41.4-1.31.3-1.3-1.4-1.0-1.5-1.5-1.5-1.31.00.21.71.7-1.6-1.51.6-1.4
Intermittent access terminal intake (last 3 days)0.81.11.9-0.3-0.60.60.20.4-1.21.2-1.11.1-1.1-1.1-0.7-1.3-1.2-1.2-1.01.00.21.41.4-1.3-1.21.3-1.2
Intermittent access total infusions1.92.23.1-1.0-1.41.40.91.3-1.61.6-1.51.5-1.5-1.5-1.3-1.7-1.8-1.8-1.71.10.11.81.8-1.7-1.61.7-1.5
Intermittent access day 1 locomotion1.31.73.5-0.1-0.50.60.10.6-1.21.2-1.11.1-1.1-1.2-1.1-1.5-1.5-1.5-1.31.00.61.91.9-1.8-1.81.9-1.8
Intermittent access day 15 total locomotion2.85.18.2-1.9-1.91.91.91.9-2.92.9-2.82.8-2.8-2.9-1.7-2.7-2.2-2.5-2.12.8-1.62.12.1-2.0-2.01.5-0.9
Intermittent access total locomotion2.83.46.2-0.7-1.21.20.61.3-1.81.8-1.71.7-1.7-1.8-1.6-2.1-2.1-2.2-2.01.40.52.52.5-2.4-2.42.4-2.2
Intermittent access standard deviation1.53.04.9-1.4-1.41.31.30.9-2.22.2-2.12.1-2.1-2.2-1.4-2.2-1.8-2.0-1.41.6-1.21.91.9-1.9-1.61.4-1.5
Left kidney weight1.15.08.7-2.0-2.62.51.82.2-2.22.2-2.22.2-2.2-2.1-2.9-2.6-2.6-2.6-2.51.1-0.52.32.3-2.4-2.42.1-2.4
Right kidney weight2.611.920.4-2.9-3.73.72.73.5-3.33.3-3.33.3-3.3-3.3-4.5-3.8-4.0-4.0-3.92.0-0.43.63.6-3.7-3.73.3-3.6
Cocaine induced anxiety3.44.89.53.12.9-2.9-3.0-2.82.7-2.72.5-2.52.52.32.72.02.41.92.2-1.21.9-0.7-0.70.70.9-0.20.0
Post-drug Anxiety1.21.32.71.21.4-1.4-1.1-1.31.3-1.31.1-1.11.11.11.61.11.61.21.50.2-0.2-0.8-0.80.80.9-0.91.2
Baseline Anxiety1.92.25.1-2.2-1.81.82.31.9-1.61.6-1.71.7-1.7-1.4-1.5-1.0-1.1-0.9-1.11.6-2.2-0.2-0.20.20.1-0.81.5
Tail length0.00.20.6-0.7-0.50.50.70.6-0.30.3-0.30.3-0.3-0.4-0.5-0.4-0.3-0.4-0.3-0.1-0.80.20.2-0.2-0.2-0.1-0.1
Length with tail0.42.05.4-2.3-2.12.02.32.2-1.51.5-1.41.4-1.4-1.2-1.3-1.1-1.3-1.0-1.30.7-1.70.00.00.0-0.2-0.4-0.1
Length without tail1.65.013.3-3.6-3.33.33.63.3-2.52.5-2.42.4-2.4-2.0-1.9-1.7-1.8-1.6-2.01.8-2.9-0.1-0.10.1-0.2-0.80.3
Times rat made contact with spout0.10.10.40.10.00.0-0.10.2-0.10.1-0.20.2-0.20.0-0.3-0.1-0.4-0.2-0.40.00.60.30.3-0.3-0.40.5-0.4
Lifetime Intake1.82.23.1-0.9-1.41.40.91.4-1.61.6-1.41.4-1.4-1.4-1.5-1.7-1.8-1.8-1.71.00.11.71.7-1.7-1.61.7-1.5
Liver weight, left3.76.211.0-2.8-2.82.82.62.2-3.03.0-2.92.9-2.9-3.3-2.4-2.8-2.4-2.5-2.32.8-2.11.71.7-1.8-1.91.0-1.6
Liver weight, right3.86.610.2-2.4-3.03.02.22.7-2.72.7-2.72.7-2.7-2.8-3.0-2.6-3.1-2.7-3.21.70.22.12.1-2.2-2.22.1-2.7
Locomotor activity0.91.52.3-1.0-1.41.40.91.4-1.01.0-1.01.0-1.0-1.4-1.5-1.3-1.3-1.4-1.40.4-0.11.41.4-1.3-1.41.3-1.0
Locomotor testing distance1.32.35.0-0.8-1.51.60.61.5-1.11.1-1.01.0-1.0-1.3-2.0-1.6-1.7-1.8-1.70.50.62.22.2-2.0-1.92.1-1.7
Locomotor testing rearing0.81.64.4-0.2-0.80.80.10.6-0.90.9-0.80.8-0.8-1.2-1.4-1.5-1.1-1.6-1.00.8-0.12.12.1-2.0-1.81.8-1.7
Locomotion in novel chamber0.81.05.71.50.8-0.8-1.5-0.61.1-1.11.1-1.11.11.30.40.90.30.60.0-0.92.4-0.3-0.30.30.00.6-1.0
Locomotion in novel chamber post-restriction0.91.45.41.61.0-1.0-1.5-0.71.6-1.61.5-1.51.51.70.71.30.60.90.4-1.52.3-0.4-0.40.40.50.3-0.3
Fecal boli incidents, locomotor time 11.01.42.9-1.5-1.51.61.51.6-1.11.1-0.90.9-0.9-1.2-1.7-1.2-1.1-1.3-1.0-0.2-1.11.21.2-1.2-1.00.8-0.0
Change in fecal boli incidents, locomotor task4.64.56.62.12.4-2.5-2.1-2.42.2-2.22.1-2.12.12.42.62.42.22.52.1-0.81.3-2.3-2.32.32.1-1.60.7
Time >=10cm from walls, locomotor time 13.73.95.52.22.4-2.2-1.9-1.62.3-2.32.2-2.22.22.32.02.22.02.11.9-0.80.8-1.8-1.81.81.9-1.52.0
Bouts of movement, locomotor time 12.02.33.5-1.7-1.51.51.71.3-1.81.8-1.91.9-1.9-1.6-1.2-1.8-1.5-1.6-1.11.7-1.61.41.4-1.4-1.10.7-0.3
Total resting periods, locomotor time 11.71.92.8-1.4-1.31.31.41.2-1.61.6-1.71.7-1.7-1.3-1.1-1.6-1.5-1.5-1.01.7-1.21.51.5-1.5-1.10.8-0.3
Rest time, locomotor task time 11.41.83.7-0.9-1.31.30.81.2-1.01.0-1.01.0-1.0-1.0-1.5-1.5-1.5-1.7-1.40.90.11.91.9-1.9-1.61.8-1.2
Distance moved, locomotor task time 10.40.61.50.81.2-1.2-0.7-0.90.6-0.60.6-0.60.60.11.20.71.10.81.00.1-0.3-0.7-0.70.70.7-0.90.6
Vertical activity count, locomotor time 11.02.44.41.82.1-2.0-1.6-1.61.7-1.71.6-1.61.61.01.91.71.91.71.6-0.70.8-1.3-1.31.31.4-1.11.1
Time >=10cm from walls, locomotor time 20.40.62.40.20.6-0.5-0.1-0.20.6-0.60.3-0.30.30.70.71.00.70.90.80.4-0.4-1.0-1.01.01.4-1.21.5
Bouts of movement, locomotor time 20.30.53.11.01.1-1.1-1.1-1.70.6-0.60.5-0.50.50.40.70.30.60.51.10.20.20.10.1-0.1-0.10.1-0.3
Total resting periods, locomotor time 20.20.32.00.60.6-0.7-0.7-1.40.0-0.0-0.10.1-0.1-0.20.3-0.30.1-0.00.60.7-0.00.50.5-0.5-0.60.4-0.6
Rest time, locomotor task time 20.91.12.0-0.8-1.00.90.60.5-1.01.0-0.90.9-0.9-1.0-1.2-1.3-1.1-1.3-0.80.4-0.31.41.4-1.4-1.31.2-1.1
Distance moved, locomotor task time 20.10.10.4-0.3-0.10.20.40.4-0.00.0-0.10.1-0.1-0.60.2-0.00.2-0.0-0.00.5-0.6-0.0-0.00.00.3-0.40.7
Vertical activity count, locomotor time 20.10.21.2-0.10.00.10.40.60.5-0.50.5-0.50.5-0.20.40.40.50.30.1-0.1-0.1-0.2-0.20.20.7-0.51.1
Light reinforcement 11.02.64.52.12.1-2.1-2.0-2.01.7-1.71.7-1.71.71.71.81.61.91.61.8-0.60.9-1.1-1.11.01.2-0.71.0
Light reinforcement 22.03.14.92.22.0-1.9-2.1-2.12.1-2.12.1-2.12.12.21.71.81.81.71.7-1.71.7-1.1-1.11.01.0-0.40.8
Bone: marrow area1.22.65.2-2.3-2.12.12.21.9-1.91.9-1.91.9-1.9-1.5-2.0-1.5-1.5-1.4-1.51.6-1.50.50.5-0.6-0.70.1-0.2
Bone: maximum diameter5.410.019.3-4.4-4.34.34.34.1-3.33.3-3.33.3-3.3-3.5-3.7-3.1-2.9-3.1-3.02.9-3.31.71.7-1.8-1.80.6-0.0
Bone: maximum force1.62.86.7-2.2-2.62.62.12.5-1.61.6-1.61.6-1.6-1.2-2.3-1.4-1.8-1.6-2.01.5-0.70.90.9-1.1-1.00.7-0.1
Bone: maximum moment1.42.46.0-2.2-2.42.52.12.4-1.51.5-1.51.5-1.5-1.1-2.1-1.3-1.6-1.5-1.81.4-0.80.70.7-0.9-0.80.50.1
Mean time between licks in bursts0.41.02.6-0.00.3-0.30.1-0.50.8-0.80.8-0.80.80.71.01.10.91.21.0-0.9-0.4-1.6-1.61.51.4-1.51.2
Mean num. licks in bursts0.50.82.90.5-0.20.2-0.50.4-0.00.0-0.10.1-0.1-0.1-0.9-0.5-0.8-0.8-0.9-0.01.61.31.3-1.3-1.31.7-1.3
Cd content in liver1.01.13.41.71.2-1.2-1.6-0.91.3-1.31.3-1.31.31.10.40.80.60.50.5-1.61.80.30.3-0.3-0.20.8-0.2
Co content in liver0.30.32.40.30.0-0.0-0.30.30.0-0.00.0-0.00.00.2-0.4-0.1-0.4-0.3-0.5-0.91.10.50.5-0.5-0.50.8-1.5
Cu content in liver0.10.10.60.50.3-0.3-0.5-0.20.0-0.00.0-0.00.0-0.3-0.1-0.1-0.1-0.2-0.1-0.20.70.30.3-0.3-0.50.6-0.8
Fe content in liver0.60.71.9-1.3-0.80.81.40.9-0.50.5-0.50.5-0.5-0.2-0.10.2-0.00.2-0.10.5-1.3-1.1-1.11.11.0-1.41.3
K content in liver0.20.21.00.40.5-0.5-0.5-0.50.0-0.00.0-0.00.0-0.4-0.2-0.3-0.0-0.20.10.00.10.60.6-0.6-0.70.6-1.0
Mg content in liver0.40.41.40.60.6-0.6-0.7-0.90.1-0.10.1-0.10.1-0.6-0.2-0.60.1-0.40.5-0.2-0.31.11.1-1.1-1.20.8-0.9
Mn content in liver0.20.21.40.70.7-0.8-0.9-1.20.3-0.30.3-0.30.30.20.40.00.40.20.7-0.20.20.30.3-0.3-0.40.3-0.6
Na content in liver0.20.20.60.50.7-0.7-0.5-0.8-0.20.2-0.20.2-0.2-0.70.3-0.30.2-0.10.30.4-0.20.40.4-0.4-0.50.3-0.6
Rb content in liver1.31.53.41.31.7-1.7-1.3-1.81.4-1.41.4-1.41.40.91.40.91.61.11.8-1.1-0.5-0.7-0.70.70.5-0.80.6
Se content in liver0.50.61.20.91.1-1.1-0.9-0.90.7-0.70.7-0.70.70.60.80.70.90.80.9-0.50.1-0.6-0.60.60.6-0.50.7
Sr content in liver1.10.93.21.51.1-1.2-1.6-1.30.9-0.90.9-0.90.91.00.80.70.50.60.7-1.51.8-0.0-0.00.00.00.6-0.8
Zn content in liver0.40.51.31.00.8-0.9-1.1-1.10.5-0.50.5-0.50.5-0.20.40.00.20.00.5-0.80.90.70.7-0.7-0.70.8-1.1
Bone: minimum diameter2.64.79.6-3.1-2.93.03.02.7-2.32.3-2.32.3-2.3-2.5-2.4-2.2-1.9-2.0-1.92.0-2.51.01.0-1.2-1.20.20.3
Time in familiar zone, hab. session 10.10.10.40.2-0.10.1-0.30.0-0.00.0-0.00.0-0.00.1-0.2-0.1-0.1-0.2-0.20.00.40.40.4-0.3-0.40.5-0.6
Time in novel zone, hab. session 10.30.31.3-0.9-0.40.40.90.5-0.60.6-0.60.6-0.6-0.7-0.0-0.4-0.2-0.2-0.20.7-1.1-0.3-0.30.20.3-0.60.7
Total zone transitions, hab. session 11.62.23.5-0.8-1.31.30.71.4-1.61.6-1.51.5-1.5-1.4-1.8-1.6-1.8-1.7-1.91.60.51.61.6-1.6-1.71.7-1.0
Total locomotion distance, hab. session 10.50.70.90.90.9-0.8-0.8-0.70.9-0.90.9-0.90.90.80.91.00.91.00.8-0.50.6-0.9-0.90.90.9-0.60.8
Locomotion velocity, hab. session 10.71.01.31.11.1-1.1-1.1-1.01.1-1.11.1-1.11.10.91.11.11.01.10.9-0.60.9-1.0-1.00.90.9-0.60.7
Time in familiar zone, hab. session 21.01.13.1-1.5-0.80.81.50.8-1.31.3-1.31.3-1.3-0.90.0-0.4-0.4-0.1-0.31.4-1.7-0.7-0.70.80.8-1.20.8
Time in novel zone, hab. session 20.60.62.60.80.1-0.1-0.8-0.00.8-0.80.8-0.80.80.5-0.40.1-0.1-0.2-0.3-0.91.60.70.7-0.8-0.91.2-0.9
Total zone transitions, hab. session 21.92.43.8-1.1-1.51.51.11.5-1.71.7-1.71.7-1.7-1.7-1.9-1.7-1.9-1.7-1.91.40.21.51.5-1.6-1.71.5-1.3
Total locomotion distance, hab. session 20.00.00.20.10.0-0.0-0.0-0.00.1-0.10.1-0.10.1-0.2-0.00.1-0.20.1-0.1-0.20.4-0.2-0.20.10.00.0-0.2
Locomotion velocity, hab. session 20.00.00.20.20.1-0.1-0.1-0.10.1-0.10.1-0.10.1-0.3-0.10.0-0.20.0-0.1-0.20.4-0.0-0.0-0.1-0.10.2-0.3
Novel to familiar place preference ratio0.70.72.0-0.20.1-0.10.40.20.8-0.80.8-0.80.80.50.90.90.90.80.7-0.9-0.5-1.2-1.21.11.2-1.21.4
Novelty place preference0.50.51.6-0.2-0.00.00.40.20.7-0.70.7-0.70.70.50.70.80.80.70.6-0.9-0.5-1.0-1.00.91.0-1.01.3
Time in novel zone, NPP test0.40.51.9-0.7-0.40.40.80.50.3-0.30.3-0.30.30.10.60.50.50.50.3-0.4-0.9-1.0-1.01.01.0-1.21.4
Total zone transitions, NPP test0.60.91.6-0.7-1.00.90.60.6-1.01.0-1.01.0-1.0-1.0-1.1-1.0-1.3-1.0-1.10.40.51.01.0-0.9-0.91.0-1.1
Total locomotion distance, NPP test0.30.41.40.20.3-0.3-0.1-0.40.6-0.60.6-0.60.60.60.50.70.30.70.4-1.20.6-0.8-0.80.80.8-0.50.3
Locomotion velocity, NPP test0.60.82.40.80.7-0.7-0.7-0.81.1-1.11.1-1.11.11.00.71.00.50.90.6-1.61.2-0.8-0.80.70.8-0.40.1
Intraocular pressure2.94.27.6-2.7-2.62.62.72.8-2.42.4-2.42.4-2.4-2.0-2.0-1.9-2.1-1.9-2.32.1-1.60.90.9-0.8-0.80.30.2
Delta distance traveled before/after self-admin0.20.31.4-0.3-0.30.20.30.0-0.50.5-0.50.5-0.5-0.5-0.1-0.5-0.7-0.5-0.40.50.20.50.5-0.6-0.70.6-1.2
Delta ambulatory time before/after self-admin0.20.20.5-0.6-0.40.30.60.1-0.60.6-0.50.5-0.5-0.60.1-0.4-0.5-0.4-0.30.7-0.40.20.2-0.3-0.30.1-0.5
Parametrial fat weight10.725.144.6-6.7-6.16.16.55.7-6.06.0-6.06.0-6.0-5.8-4.6-5.1-4.7-4.7-4.65.3-5.32.62.6-2.5-2.50.9-0.7
Pavlov. Cond. lever latency0.10.11.3-0.20.1-0.10.30.0-0.40.4-0.40.4-0.4-0.70.2-0.40.1-0.20.20.3-1.10.20.2-0.2-0.2-0.20.2
Pavlov. Cond. magazine entry latency0.20.30.70.1-0.0-0.0-0.1-0.30.4-0.40.4-0.40.40.60.40.70.10.60.2-0.40.7-0.8-0.80.90.8-0.50.2
Pavlov. Cond. change in total contacts0.10.10.6-0.2-0.40.40.20.1-0.00.0-0.00.0-0.00.3-0.30.3-0.20.2-0.20.10.8-0.4-0.40.40.5-0.1-0.2
Pavlov. Cond. index score0.10.10.4-0.2-0.40.40.20.10.1-0.10.1-0.10.10.3-0.20.2-0.40.1-0.3-0.10.6-0.3-0.30.30.3-0.0-0.1
Pavlov. Cond. latency score0.10.10.4-0.2-0.50.40.20.20.0-0.00.0-0.00.00.2-0.40.1-0.4-0.0-0.4-0.10.7-0.1-0.10.10.10.2-0.2
Pavlov. Cond. lever contacts0.00.10.5-0.1-0.20.20.00.2-0.00.0-0.00.0-0.00.4-0.30.1-0.40.0-0.40.20.7-0.1-0.10.10.10.2-0.2
Pavlov. Cond. magazine entry number0.10.20.70.50.8-0.8-0.5-0.60.3-0.30.3-0.30.3-0.00.60.10.60.20.6-0.3-0.30.00.0-0.1-0.1-0.1-0.0
Pavlov. Cond. intertrial magazine entries0.20.30.7-0.1-0.10.20.30.80.4-0.40.4-0.40.40.80.00.70.10.4-0.3-0.60.6-0.7-0.70.70.8-0.40.7
Pavlov. Cond. lever-magazine prob. diff.0.10.10.3-0.2-0.30.30.20.10.2-0.20.1-0.10.10.5-0.00.4-0.10.3-0.1-0.10.5-0.5-0.50.60.6-0.30.2
Pavlov. Cond. response bias0.10.10.90.1-0.10.1-0.1-0.00.3-0.30.3-0.30.30.70.00.5-0.10.4-0.2-0.10.9-0.5-0.50.50.6-0.10.2
Pavlov. Cond. lever latency0.30.41.41.00.7-0.7-1.0-0.70.6-0.60.6-0.60.60.80.00.40.40.30.3-0.51.20.20.2-0.2-0.10.5-0.2
Pavlov. Cond. magazine entry latency0.40.41.4-0.8-0.50.50.80.2-0.90.9-0.90.9-0.9-1.0-0.1-0.6-0.5-0.4-0.41.2-1.0-0.0-0.0-0.0-0.0-0.3-0.2
Pavlov. Cond. change in total contacts0.40.62.7-1.1-0.80.81.21.0-0.70.7-0.70.7-0.7-1.0-0.3-0.7-0.4-0.6-0.40.8-1.60.10.1-0.2-0.2-0.30.3
Pavlov. Cond. index score0.50.71.7-1.2-1.01.01.31.0-0.90.9-0.90.9-0.9-1.1-0.3-0.8-0.6-0.6-0.60.9-1.30.10.1-0.1-0.2-0.30.0
Pavlov. Cond. latency score0.50.62.0-1.2-0.90.91.31.0-0.80.8-0.90.9-0.9-1.1-0.3-0.8-0.6-0.6-0.60.8-1.40.20.2-0.2-0.2-0.30.1
Pavlov. Cond. lever contacts0.20.30.8-0.9-0.70.70.90.7-0.60.6-0.60.6-0.6-0.8-0.3-0.5-0.5-0.5-0.50.4-0.80.10.1-0.1-0.1-0.1-0.2
Pavlov. Cond. magazine entry number0.30.41.10.80.5-0.5-0.8-0.20.8-0.80.8-0.80.80.90.20.60.50.40.3-1.01.0-0.0-0.00.10.10.20.3
Pavlov. Cond. intertrial magazine entries0.10.20.3-0.2-0.00.00.2-0.0-0.60.6-0.50.5-0.5-0.5-0.4-0.5-0.4-0.4-0.20.5-0.30.60.6-0.5-0.30.30.0
Pavlov. Cond. lever-magazine prob. diff.0.50.71.5-1.2-1.01.01.21.0-0.90.9-1.01.0-1.0-1.2-0.4-0.8-0.7-0.7-0.70.9-1.20.30.3-0.3-0.3-0.1-0.2
Pavlov. Cond. response bias0.30.51.3-1.1-0.80.81.10.8-0.70.7-0.80.8-0.8-0.8-0.2-0.5-0.5-0.4-0.50.7-1.1-0.2-0.20.10.1-0.40.1
Time in closed arm before self-admin0.20.20.60.50.5-0.6-0.6-0.7-0.00.0-0.10.1-0.1-0.20.6-0.30.1-0.20.20.80.20.80.8-0.6-0.40.5-0.4
Time in closed arm after self-admin0.80.81.81.20.9-1.0-1.3-1.41.0-1.01.0-1.01.00.70.90.40.40.30.6-0.81.30.50.5-0.5-0.30.8-1.3
Time in open arm before self-admin2.62.84.71.11.3-1.3-1.1-1.21.8-1.81.9-1.91.92.01.12.21.82.01.7-1.70.8-2.0-2.01.92.0-1.61.5
Time in open arm after self-admin0.30.31.8-0.5-0.30.40.70.9-0.20.2-0.20.2-0.2-0.3-0.40.00.20.1-0.20.3-0.9-0.7-0.70.70.4-0.81.3
Bone: periosteal estimation3.88.115.2-3.8-3.93.93.83.7-3.03.0-3.03.0-3.0-2.9-3.5-2.8-2.8-2.8-2.92.6-2.41.51.5-1.7-1.70.8-0.2
Bone: periosteal perimeter10.117.425.9-4.9-5.15.14.74.9-4.44.4-4.44.4-4.4-4.6-5.0-4.5-4.2-4.5-4.33.8-3.33.33.3-3.4-3.32.0-1.2
Bone: post-yield work0.91.33.30.20.3-0.3-0.1-0.60.8-0.80.8-0.80.81.01.01.41.11.40.9-0.70.1-1.8-1.81.81.8-1.61.8
Progressive ratio test 1 active lever presses1.62.03.4-0.5-1.01.00.51.0-1.51.5-1.31.3-1.3-1.5-1.3-1.6-1.6-1.7-1.51.10.41.81.8-1.8-1.81.8-1.5
Progressive ratio test 1 breakpoint1.61.93.4-0.5-1.01.00.51.1-1.41.4-1.31.3-1.3-1.4-1.4-1.6-1.6-1.6-1.51.10.41.81.8-1.8-1.81.8-1.4
Progressive ratio test 1 inactive lever presses0.10.20.4-0.2-0.20.20.20.3-0.60.6-0.50.5-0.5-0.5-0.1-0.5-0.5-0.5-0.50.30.00.50.5-0.5-0.40.5-0.6
Progressive ratio test 2 active lever presses2.83.34.8-1.2-1.51.51.11.5-2.12.1-2.02.0-2.0-2.1-1.4-2.2-1.9-2.1-1.81.9-0.52.02.0-2.0-1.91.8-1.6
Progressive ratio test 2 breakpoint2.93.34.8-1.2-1.51.51.21.5-2.12.1-2.02.0-2.0-2.2-1.3-2.2-1.8-2.1-1.91.9-0.52.02.0-2.0-1.91.7-1.5
Progressive ratio test 2 inactive lever presses1.11.82.9-1.5-1.51.51.51.6-1.71.7-1.51.5-1.5-1.6-1.0-1.5-1.4-1.4-1.40.9-1.10.90.9-0.9-0.90.6-0.6
Incentive Sensitization - Responses1.21.72.8-1.2-1.21.21.11.2-1.71.7-1.61.6-1.6-1.7-0.8-1.6-1.1-1.4-1.21.5-1.11.11.1-1.1-1.00.8-0.8
Incentive Sensitization - Breakpoint1.21.52.6-1.1-1.11.11.11.1-1.61.6-1.61.6-1.6-1.6-0.6-1.5-1.0-1.3-1.11.5-1.11.01.0-1.0-0.90.6-0.7
Sum of active levers in priming session hrs 5-60.10.10.60.50.8-0.8-0.5-0.30.1-0.10.1-0.10.10.10.50.20.30.30.30.1-0.1-0.4-0.40.30.2-0.30.3
Progressive ratio0.40.61.10.81.0-1.0-0.7-1.00.8-0.80.7-0.70.71.00.80.71.00.80.9-0.10.0-0.7-0.70.70.5-0.60.8
Food seeking constrained by brief footshock0.70.94.20.51.0-1.1-0.5-1.50.4-0.40.4-0.40.40.82.00.81.11.01.40.8-0.5-0.8-0.80.81.2-1.10.5
Seeking ratio, punishment vs. effort0.20.31.2-0.3-0.40.30.2-0.0-0.70.7-0.60.6-0.6-0.70.1-0.6-0.6-0.5-0.30.60.00.70.7-0.7-0.50.6-1.1
Retroperitoneal fat weight8.536.174.2-8.6-7.97.88.37.1-7.37.3-7.27.2-7.2-6.6-5.3-5.7-5.7-5.2-5.56.0-6.22.12.1-2.1-2.20.2-1.1
Reaction time number correct1.01.93.4-1.3-1.21.31.31.2-1.61.6-1.61.6-1.6-1.6-1.6-1.6-1.2-1.4-1.11.8-1.31.21.2-1.2-1.30.70.1
Reaction time mean minus median0.51.21.8-0.7-0.90.90.60.9-1.11.1-1.11.1-1.1-1.3-1.1-1.3-1.1-1.3-1.20.9-0.31.31.3-1.2-1.21.1-1.0
Reaction time mean minus median AUC0.82.04.2-0.4-0.80.80.30.6-1.21.2-1.21.2-1.2-1.3-1.5-1.7-1.5-1.7-1.40.90.22.12.1-1.9-1.92.0-1.9
Reaction time num false alarms0.10.10.6-0.1-0.10.10.10.3-0.10.1-0.10.1-0.10.1-0.30.3-0.20.2-0.2-0.10.8-0.3-0.30.30.4-0.1-0.5
Reaction time num false alarms AUC0.10.10.8-0.1-0.10.20.10.5-0.20.2-0.20.2-0.2-0.1-0.50.0-0.4-0.1-0.50.10.90.10.1-0.10.10.3-0.8
Reaction time trials correct on left1.01.93.4-1.3-1.21.31.31.2-1.61.6-1.61.6-1.6-1.6-1.6-1.6-1.2-1.4-1.11.8-1.31.21.2-1.2-1.30.70.1
Reaction time trials on left1.12.13.6-1.4-1.31.41.41.3-1.71.7-1.71.7-1.7-1.6-1.7-1.7-1.3-1.5-1.21.9-1.41.31.3-1.2-1.30.70.0
Reaction time mean0.61.02.1-0.7-1.01.00.70.8-1.01.0-1.01.0-1.0-1.1-0.9-1.1-1.3-1.1-1.20.20.21.11.1-0.9-1.11.1-1.4
Reaction time mean AUC0.40.61.8-0.3-0.60.50.30.4-0.70.7-0.70.7-0.7-1.0-0.6-0.9-0.9-0.9-0.80.00.21.11.1-0.9-1.11.0-1.3
Median of all reaction times0.50.82.2-0.6-0.90.80.50.6-0.80.8-0.80.8-0.8-0.9-0.8-0.9-1.2-0.9-1.10.00.51.01.0-0.7-1.01.0-1.5
Reaction time omissions0.71.01.9-1.0-0.80.80.90.8-1.41.4-1.41.4-1.4-1.3-0.6-1.2-0.9-1.0-0.91.3-0.90.70.7-0.5-0.60.3-0.7
Reaction time false alarm rate0.40.51.90.60.5-0.5-0.5-0.20.6-0.60.6-0.60.60.80.51.00.30.90.2-0.81.4-0.9-0.90.91.1-0.4-0.5
Reaction time premature initiation rate0.40.61.90.2-0.50.5-0.20.6-0.30.3-0.20.2-0.2-0.1-0.8-0.6-0.9-0.8-1.0-0.11.31.01.0-1.0-1.01.4-1.3
Reaction time premature initiations1.12.03.5-0.6-1.21.20.51.4-1.21.2-1.21.2-1.2-1.1-1.8-1.6-1.6-1.7-1.71.10.41.91.9-1.8-1.81.9-1.3
Std. dev. reaction times1.73.14.2-1.7-1.91.91.61.7-1.91.9-1.91.9-1.9-2.0-1.8-2.0-2.1-2.0-2.01.1-0.61.71.7-1.5-1.71.4-1.6
Reaction time trials completed1.12.13.6-1.4-1.31.41.41.3-1.71.7-1.71.7-1.7-1.6-1.7-1.7-1.3-1.5-1.21.9-1.41.31.3-1.2-1.30.70.0
Reaction time trials AUC1.12.13.5-1.5-1.41.41.41.3-1.71.7-1.71.7-1.7-1.6-1.8-1.7-1.3-1.5-1.21.9-1.41.31.3-1.2-1.30.70.0
Run reversals in cocaine runway, females1.01.02.1-0.8-1.21.20.71.4-0.90.9-0.90.9-0.9-1.0-1.0-1.1-1.1-1.2-1.40.10.00.70.7-0.7-1.20.9-1.4
Run reversals in cocaine runway, males1.21.23.11.41.7-1.7-1.3-1.81.1-1.11.1-1.11.10.81.50.91.40.91.7-0.20.10.20.2-0.20.5-0.20.6
Latency to leave start box in cocaine runway0.40.52.60.81.1-1.2-0.9-1.60.5-0.50.5-0.50.50.30.70.30.90.51.2-0.3-0.6-0.0-0.00.00.1-0.3-0.3
Latency to leave start box in cocaine runway, F1.11.33.61.21.6-1.6-1.3-1.91.2-1.21.2-1.21.21.21.10.91.41.11.7-0.8-0.3-0.6-0.60.60.7-0.70.3
Latency to leave start box in cocaine runway, M0.70.71.7-0.4-0.30.20.3-0.1-1.11.1-1.01.0-1.0-1.3-0.3-1.1-0.6-0.8-0.41.0-0.60.80.8-0.8-0.90.6-1.1
Std. dev. time between licks in bursts0.81.13.00.10.4-0.4-0.1-0.50.9-0.90.9-0.90.91.20.91.30.81.30.8-1.20.2-1.7-1.71.71.5-1.31.0
Total sessions with >9 infusions2.73.35.5-1.7-2.32.31.62.3-2.02.0-1.81.8-1.8-1.7-2.2-1.8-2.3-2.0-2.30.7-0.01.61.6-1.6-1.61.6-1.3
Short access day 1 total inactive lever presses0.70.91.90.30.7-0.7-0.3-0.70.8-0.80.9-0.90.91.01.21.20.91.21.0-1.0-0.1-1.3-1.31.41.3-1.30.7
Short access day 10 total inactive lever presses0.20.40.8-0.6-0.60.60.60.3-0.60.6-0.60.6-0.6-0.9-0.6-0.8-0.7-0.7-0.50.0-0.40.60.6-0.6-0.70.5-0.8
Short access day 1 total infusions0.40.51.4-0.3-0.70.70.20.5-0.60.6-0.50.5-0.5-0.3-0.9-0.7-1.1-0.8-0.9-0.20.70.90.9-0.9-0.81.1-1.2
Short access day 10 total infusions0.50.72.00.1-0.50.5-0.20.5-0.40.4-0.30.3-0.3-0.2-1.0-0.6-0.9-0.8-0.9-0.21.21.21.2-1.2-1.11.4-1.3
Short access total infusions0.70.92.1-0.3-1.01.00.21.1-0.60.6-0.50.5-0.5-0.5-1.2-0.9-1.2-1.1-1.3-0.10.91.21.2-1.3-1.11.5-1.3
Short access day 1 locomotion1.62.03.5-0.8-1.11.00.70.7-1.71.7-1.51.5-1.5-1.5-1.3-1.6-1.9-1.5-1.40.90.21.71.7-1.6-1.61.6-1.6
Short access day 10 total locomotion2.03.65.3-1.2-1.61.61.11.6-2.12.1-2.02.0-2.0-1.9-1.9-2.2-2.3-2.2-2.11.80.12.22.2-2.1-2.12.0-1.7
Short access total locomotion3.54.26.6-1.1-1.81.81.01.7-2.12.1-2.02.0-2.0-1.9-2.2-2.3-2.6-2.4-2.41.30.52.52.5-2.5-2.42.5-2.2
One hour access (0.3 mA shock)0.81.02.0-1.1-1.01.01.10.7-1.41.4-1.31.3-1.3-1.4-0.3-1.1-0.9-0.9-0.71.3-1.10.60.6-0.4-0.60.2-0.3
Compulsive drug intake0.60.82.20.10.6-0.60.0-0.70.5-0.50.4-0.40.40.31.10.90.91.11.0-0.4-0.6-1.4-1.41.51.2-1.51.0
One hour access (shock baseline)1.32.13.3-0.8-1.31.30.81.1-1.51.5-1.41.4-1.4-1.3-1.4-1.7-1.6-1.7-1.51.1-0.21.81.8-1.8-1.71.7-1.5
Social response proportion1.82.04.4-0.8-1.41.40.71.5-1.31.3-1.41.4-1.4-1.0-1.8-1.3-2.0-1.5-2.10.71.31.31.3-1.2-1.61.7-1.8
Social responses4.66.09.0-2.5-2.52.62.52.8-3.03.0-3.03.0-3.0-2.9-2.3-2.6-2.6-2.5-2.72.7-1.41.91.9-1.6-1.91.3-1.1
Social time2.02.84.3-1.0-1.41.41.01.6-1.81.8-1.81.8-1.8-1.7-1.8-1.8-2.0-1.9-2.11.40.31.71.7-1.6-1.81.7-1.8
Soleus weight4.112.117.7-3.1-3.83.72.83.2-3.83.8-3.83.8-3.8-3.3-4.2-3.8-4.1-3.8-3.83.0-0.63.43.4-3.4-3.33.0-3.3
Bone: stiffness1.32.25.4-1.8-2.32.31.72.0-1.31.3-1.31.3-1.3-1.0-2.3-1.3-1.5-1.5-1.71.3-0.50.90.9-1.0-1.00.8-0.1
Tibialis anterior weight0.30.93.2-1.4-1.01.01.41.0-1.01.0-1.01.0-1.0-1.3-0.7-1.0-0.7-0.8-0.51.4-1.80.40.4-0.5-0.4-0.20.3
Time to tail flick, vehicle, before self-admin0.20.20.5-0.6-0.60.60.60.7-0.20.2-0.20.2-0.2-0.4-0.2-0.5-0.3-0.6-0.50.4-0.70.30.3-0.3-0.30.10.1
Time to tail flick, vehicle, after self-admin0.10.21.40.40.7-0.6-0.3-0.30.2-0.20.2-0.20.20.00.20.30.50.40.60.2-0.3-0.2-0.20.30.4-0.41.2
Time to tail flick, test, before self-admin1.61.76.00.4-0.60.5-0.50.2-0.40.4-0.40.4-0.4-0.4-1.2-1.0-1.4-1.3-1.3-0.62.21.91.9-1.9-1.72.4-2.4
Time to tail flick, test, after self-admin0.70.71.8-1.1-1.11.11.11.3-0.70.7-0.80.8-0.8-1.1-0.5-0.8-0.5-0.8-0.80.9-1.10.40.4-0.4-0.30.10.7
Delta time to tail flick, vehicle, before/after SA0.20.20.9-0.20.2-0.10.3-0.1-0.60.6-0.60.6-0.6-0.5-0.1-0.10.20.10.40.5-1.0-0.2-0.20.20.3-0.61.0
Delta time to tail flick, test, before/after SA0.60.73.1-1.2-0.80.91.31.4-0.40.4-0.40.4-0.4-0.7-0.3-0.30.1-0.3-0.30.8-1.8-0.3-0.30.20.3-0.81.6
Tibia length1.33.56.0-1.5-1.92.01.42.3-1.91.9-2.02.0-2.0-1.9-2.4-1.9-2.2-2.1-2.41.70.11.71.7-1.7-1.71.7-1.4
Ambulatory time before self-admin0.50.73.00.90.1-0.1-1.0-0.10.1-0.10.1-0.10.10.4-0.9-0.4-0.5-0.6-0.6-0.41.71.21.2-1.1-1.01.6-1.2
Ambulatory time after self-admin0.60.72.90.80.2-0.2-0.9-0.30.0-0.0-0.00.0-0.00.3-0.8-0.4-0.7-0.6-0.60.01.71.11.1-1.2-1.01.6-1.5
Bone: tissue strength0.10.10.40.20.3-0.4-0.3-0.60.3-0.30.3-0.30.30.30.60.20.50.30.60.1-0.3-0.2-0.20.20.2-0.30.3
Total heroin consumption1.31.53.0-1.4-1.11.11.41.2-1.71.7-1.71.7-1.7-1.6-1.0-1.3-1.2-1.1-1.01.7-1.30.60.6-0.6-0.50.10.1
Bone: trabecular number0.71.13.0-1.6-1.21.21.61.0-0.90.9-0.90.9-0.9-0.50.1-0.1-0.20.1-0.31.1-1.5-1.1-1.11.01.0-1.31.7
Bone: trabecular spacing0.10.20.60.60.8-0.7-0.5-0.50.5-0.50.4-0.40.40.20.40.20.50.30.5-0.3-0.10.00.00.10.0-0.1-0.1
Bone: trabecular thickness4.15.110.3-3.2-3.13.03.12.6-2.62.6-2.62.6-2.6-2.3-2.3-2.2-2.1-2.1-2.02.2-2.31.11.1-1.2-1.10.30.2
Bone: trabecular tissue density0.50.71.8-0.2-0.70.70.30.8-0.40.4-0.40.4-0.4-0.6-1.3-0.8-0.8-1.0-0.90.10.51.21.2-1.2-1.21.2-1.3
Water consumed over 24 hours0.10.20.5-0.1-0.30.30.10.4-0.20.2-0.20.2-0.2-0.1-0.6-0.3-0.5-0.5-0.5-0.10.50.60.6-0.6-0.60.7-0.5
Number of responses in last shaping day0.91.02.8-0.1-0.60.6-0.10.4-0.60.6-0.50.5-0.5-0.6-1.2-1.1-1.0-1.2-1.0-0.20.81.61.6-1.6-1.51.7-1.7