Hub : Genes

LOC120098271

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R² and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

#	Tissue	Modality	RNA phenotype	h2	h2 SE	h2 P	xQTL R2	BLUP R2	ENET R2	LASSO R2	xQTL P	BLUP P	ENET P	LASSO P
1	PL	gene expression	LOC120098271	0.03	0.02	1.8e-03	0.01	0.02	0.02	0.02	1.2e-02	1.5e-03	2.5e-03	4.8e-03
2	BLA	gene expression	LOC120098271	0.05	0.03	2.5e-03	0.03	0.02	0	0.03	7.0e-03	2.2e-02	1.8e-01	1.2e-02
3	NAcc	gene expression	LOC120098271	0.02	0.01	4.1e-03	0	0.02	0.02	0.01	1.1e-01	2.1e-03	5.5e-03	1.2e-02

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3
Bone: apparent density	0.2	0.3	0.4	0.6	-0.4	0.6
Area under the delay curve	5.0	5.3	6.0	2.5	-2.4	2.1
BMI with tail	6.2	20.1	24.1	-4.9	4.5	-4.0
BMI without tail	4.3	8.8	9.7	-3.1	3.0	-2.8
Body weight	6.6	27.6	31.4	-5.6	5.5	-4.6
Weight adjusted by age	1.6	1.8	2.8	-1.3	1.7	-1.0
Bone surface	0.5	0.9	1.3	0.8	-1.1	0.9
Bone volume	0.3	0.4	0.7	0.6	-0.8	0.6
Breakpoint value in progressive ratio session	0.0	0.1	0.1	-0.1	0.3	-0.2
Number of licking bursts	0.8	0.9	1.2	0.8	-0.9	1.1
Context. condit. distance diff. score	0.0	0.0	0.0	0.1	0.0	0.0
Locomotion velocity, session 1	0.8	0.9	1.5	-1.1	0.3	-1.2
Locomotion distance, session 1	0.0	0.1	0.1	-0.3	0.1	-0.3
Locomotion velocity, session 2	0.7	0.8	1.5	-1.2	0.4	-0.8
Locomotion distance, session 2	0.4	0.5	0.8	0.6	-0.9	0.7
Locomotion velocity, session 3	0.3	0.4	0.6	-0.6	0.4	-0.7
Locomotion distance, session 3	0.1	0.1	0.1	0.4	0.1	0.2
Stereotopy head waving bouts, day 3	2.8	3.3	5.0	1.6	-2.2	1.5
Stereotopy head waving duration, day 3	0.5	0.6	1.6	0.5	-1.3	0.3
Locomotion velocity, session 7	0.1	0.1	0.2	-0.4	0.4	-0.2
Locomotion distance, session 7	0.3	0.4	0.7	0.8	-0.1	0.8
Stereotopy head waving bouts, day 7	0.2	0.3	0.3	-0.6	0.5	-0.5
Stereotopy head waving duration, day 7	0.1	0.1	0.2	-0.4	0.1	-0.3
Locomotion velocity, session 8	0.2	0.3	0.4	-0.6	-0.3	-0.6
Locomotion distance, session 8	0.0	0.0	0.1	0.1	-0.3	-0.1
Degree of sensitization distance	0.1	0.1	0.1	-0.2	0.4	0.2
Degree of sensitization stereotypy	0.2	0.2	0.2	-0.5	0.5	-0.3
Conditioned locomotion	0.0	0.0	0.0	-0.1	0.1	0.1
Cocaine response after cond. corrected	1.1	1.3	1.6	-1.0	1.1	-1.3
Cocaine response after cond. not corrected	0.2	0.2	0.4	-0.2	0.6	-0.5
Cocaine response before conditioning	4.3	5.2	6.6	2.2	-2.0	2.6
Saline control response	0.4	0.6	1.1	0.8	0.1	1.0
Bone: connectivity density	1.4	2.2	2.7	1.5	-1.6	1.3
Bone: cortical apparent density	0.9	1.2	1.3	1.2	-1.0	1.1
Bone: cortical area	2.3	3.5	4.5	2.0	-1.3	2.1
Bone: cortical porosity	1.0	1.1	1.4	-1.0	0.9	-1.2
Bone: cortical porosity	0.7	0.8	1.0	-0.8	0.8	-1.0
Bone: cortical thickness	2.2	3.6	5.1	2.0	-1.3	2.2
Bone: cortical thickness	0.3	0.3	0.6	0.6	-0.1	0.8
Bone: cortical tissue density	0.7	0.9	1.0	1.0	-0.9	1.0
Condit. Reinf. active minus inactive responses	2.6	2.9	4.5	1.6	-2.1	1.3
Condit. Reinf. active-inactive response ratio	1.7	1.8	1.9	1.4	-1.4	1.3
Condit. Reinf. active responses	1.5	1.9	3.4	1.3	-1.8	0.8
Condit. Reinf. inactive responses	0.5	0.6	1.1	0.7	-1.1	0.3
Incentive salience index mean	1.8	2.1	3.1	1.4	-1.8	1.1
Condit. Reinf. lever presses	0.8	1.0	1.6	1.2	-0.8	0.9
Condit. Reinf. active minus inactive responses	2.0	2.5	3.7	1.9	-1.5	1.3
Condit. Reinf. active-inactive response ratio	0.2	0.2	0.4	-0.0	0.3	-0.6
Condit. Reinf. active responses	6.1	8.5	10.8	3.3	-2.7	2.7
Condit. Reinf. inactive responses	7.6	9.3	10.2	3.2	-2.9	3.1
Condit. Reinf. lever presses	1.3	1.7	2.3	1.5	-1.1	1.2
Condit. Reinf. lever reinforcers received	5.6	7.9	9.8	3.1	-2.7	2.6
Conditioned reinforcement - actives	0.1	0.1	0.2	-0.0	0.3	-0.5
Conditioned reinforcement - inactives	0.0	0.0	0.1	0.2	-0.2	0.2
Conditioned locomotion	0.0	0.0	0.0	0.2	0.0	-0.1
Patch foraging indifference point 0 sec	2.0	3.3	3.9	2.0	-1.5	1.9
Patch foraging indifference point AUC	3.5	4.0	4.8	2.0	-2.2	1.9
Delay disc. indifference point, 0s delay	1.8	2.0	2.3	1.5	-1.4	1.3
Delay disc. indifference point, 16s delay	5.9	5.9	6.5	2.5	-2.4	2.4
Delay disc. indifference point, 2s delay	0.9	1.1	1.3	1.1	-1.1	0.8
Delay disc. indifference point, 24s delay	1.0	1.0	1.2	1.1	-1.0	0.7
Delay disc. indifference point, 4s delay	1.0	1.1	1.4	1.2	-1.1	0.8
Delay disc. indifference point, 8s delay	6.1	6.3	7.4	2.7	-2.5	2.2
Indifference point function ln k	8.7	12.1	15.6	-3.4	3.9	-3.1
Indifference point function log k	8.7	12.1	15.6	-3.4	3.9	-3.1
Patch foraging total patch changes 0 sec	2.0	3.2	3.6	1.9	-1.6	1.8
Patch foraging total patch changes 12 sec	9.3	12.1	13.1	3.4	-3.6	3.4
Patch foraging total patch changes 18 sec	5.0	6.4	7.1	2.7	-2.6	2.3
Patch foraging total patch changes 24 sec	3.3	4.0	4.3	2.0	-1.9	2.1
Patch foraging total patch changes 6 sec	3.7	5.5	6.4	2.5	-2.2	2.3
Patch foraging time to switch 0 sec	0.1	0.1	0.2	-0.3	0.2	-0.5
Patch foraging water rate 0 sec	0.0	0.0	0.0	-0.0	0.1	0.1
Patch foraging water rate 12 sec	0.8	1.2	2.3	-0.9	1.5	-0.8
Patch foraging water rate 18 sec	0.4	0.5	0.6	-0.5	0.8	-0.8
Patch foraging water rate 24 sec	0.4	0.6	1.1	-0.7	0.5	-1.0
Patch foraging water rate 6 sec	0.1	0.2	0.2	-0.4	0.5	-0.5
Seeking ratio, delayed vs. immediate footshock	0.2	0.2	0.4	0.6	-0.2	0.6
Distance traveled before self-admin	0.3	0.3	0.7	0.8	-0.4	0.3
Distance traveled after self-admin	0.5	0.5	1.3	1.1	-0.6	0.1
Extensor digitorum longus weight	1.9	7.7	10.0	-2.7	3.2	-2.3
Bone: elastic displacement	1.2	1.4	1.6	-1.2	1.0	-1.3
Bone: elastic work	2.2	2.8	3.2	-1.7	1.8	-1.6
Bone: endosteal estimation	0.4	0.9	1.6	0.7	-1.3	0.7
Bone: endosteal perimeter	0.1	0.2	0.3	0.3	-0.5	0.3
Epididymis fat weight	4.6	10.8	12.4	-3.5	2.9	-3.4
Delta time in closed arm before/after self-admin	3.2	3.1	3.8	-2.0	1.4	-1.9
Delta time in open arm before/after self-admin	1.4	1.3	2.1	0.9	-1.1	1.5
Diff in mean of infusions in LGA sessions	1.9	2.1	2.8	-1.1	1.7	-1.5
Delay discount exponential model param	5.2	5.5	6.2	-2.5	2.4	-2.1
Extinction: sum of active levers before priming	0.1	0.1	0.2	-0.1	0.4	-0.4
Active lever presses in extinction session 6	1.5	1.5	2.0	1.4	-0.9	1.3
Bone: final force	1.2	1.9	2.0	1.4	-1.3	1.4
Bone: final moment	0.5	0.9	0.9	1.0	-0.9	1.0
Food consumed during 24 hour testing period	1.2	1.5	1.8	-1.2	1.3	-1.1
Glucose	7.9	11.9	13.4	-3.3	3.7	-3.4
Heart weight	3.1	4.3	6.3	-2.1	2.5	-1.5
Delay discount hyperbolic model param	4.7	5.0	5.6	-2.4	2.3	-2.0
Intermittent access intake day 1-15 change	0.3	0.3	0.7	-0.8	0.5	-0.3
Intermittent access intake escalation	0.1	0.1	0.3	-0.5	0.3	-0.1
Intermittent access intake escalation 2	0.2	0.2	0.3	-0.5	0.5	-0.1
Intermitt. access day 1 inactive lever presses	0.1	0.1	0.1	-0.4	0.1	-0.2
Intermitt. access day 15 inactive lever presses	0.2	0.2	0.2	-0.5	0.5	-0.4
Intermitt. access escalation Index	1.5	1.3	1.8	-1.3	1.0	-1.1
Intermittent access day 1 total infusions	0.0	0.1	0.1	0.2	-0.3	-0.1
Intermittent access day 15 total infusions	0.0	0.0	0.0	-0.1	-0.2	-0.2
Intermittent access terminal intake (last 3 days)	0.0	0.0	0.0	-0.0	-0.0	0.0
Intermittent access total infusions	0.1	0.2	0.3	-0.3	0.2	-0.6
Intermittent access day 1 locomotion	0.2	0.2	0.4	-0.3	0.2	-0.6
Intermittent access day 15 total locomotion	3.6	3.9	4.3	-2.1	2.0	-1.9
Intermittent access total locomotion	1.8	2.1	2.2	-1.4	1.4	-1.5
Intermittent access standard deviation	0.1	0.1	0.1	-0.3	-0.3	-0.2
Left kidney weight	0.3	0.9	1.3	-0.9	1.1	-0.7
Right kidney weight	0.3	0.8	1.4	-0.9	1.2	-0.3
Cocaine induced anxiety	0.1	0.2	0.4	-0.3	0.1	-0.6
Post-drug Anxiety	0.2	0.2	0.4	0.4	-0.2	0.6
Baseline Anxiety	0.6	0.6	1.5	0.6	-0.3	1.2
Tail length	0.1	0.3	0.4	-0.5	0.6	-0.5
Length with tail	0.8	2.8	4.2	-1.6	2.0	-1.3
Length without tail	0.8	1.8	2.6	-1.4	1.6	-0.9
Times rat made contact with spout	0.3	0.3	0.7	-0.2	0.8	-0.4
Lifetime Intake	0.2	0.3	0.6	-0.3	0.3	-0.8
Liver weight, left	0.1	0.2	0.3	-0.5	0.4	-0.6
Liver weight, right	0.8	1.3	2.2	1.0	-1.5	0.9
Locomotor activity	0.2	0.3	0.6	0.6	-0.3	0.7
Locomotor testing distance	0.1	0.1	0.1	0.3	0.2	0.4
Locomotor testing rearing	0.5	0.8	1.1	1.0	-0.5	1.1
Locomotion in novel chamber	0.2	0.2	0.3	-0.0	-0.6	-0.5
Locomotion in novel chamber post-restriction	0.1	0.1	0.2	-0.3	0.0	0.4
Fecal boli incidents, locomotor time 1	0.1	0.1	0.2	-0.2	0.1	-0.5
Change in fecal boli incidents, locomotor task	0.2	0.2	0.3	-0.3	-0.2	-0.6
Time >=10cm from walls, locomotor time 1	0.7	0.7	1.0	-0.8	0.7	-1.0
Bouts of movement, locomotor time 1	0.8	0.9	1.0	1.0	-0.9	0.9
Total resting periods, locomotor time 1	0.6	0.7	0.8	0.9	-0.9	0.7
Rest time, locomotor task time 1	0.2	0.2	0.3	-0.5	0.4	-0.4
Distance moved, locomotor task time 1	0.2	0.2	0.4	0.3	-0.1	0.7
Vertical activity count, locomotor time 1	0.2	0.2	0.4	-0.2	0.6	0.2
Time >=10cm from walls, locomotor time 2	5.0	5.3	6.7	-2.2	2.6	-2.0
Bouts of movement, locomotor time 2	0.3	0.4	0.4	0.5	-0.6	0.6
Total resting periods, locomotor time 2	0.1	0.1	0.1	0.2	-0.3	0.3
Rest time, locomotor task time 2	1.2	1.3	1.4	-1.1	1.2	-1.2
Distance moved, locomotor task time 2	0.4	0.5	1.1	0.5	-0.2	1.1
Vertical activity count, locomotor time 2	0.5	0.6	1.1	0.7	-0.3	1.1
Light reinforcement 1	1.4	2.6	3.1	1.8	-1.6	1.5
Light reinforcement 2	4.3	5.7	6.7	2.5	-2.6	2.0
Bone: marrow area	0.4	0.9	1.7	0.7	-1.3	0.7
Bone: maximum diameter	1.9	3.4	3.8	2.0	-1.8	1.8
Bone: maximum force	0.3	0.5	0.8	0.8	-0.4	0.9
Bone: maximum moment	0.1	0.1	0.2	0.3	0.0	0.4
Mean time between licks in bursts	0.2	0.3	0.7	-0.9	0.2	-0.4
Mean num. licks in bursts	1.4	1.7	2.4	-1.0	1.5	-1.4
Cd content in liver	0.0	0.0	0.1	-0.0	-0.2	-0.2
Co content in liver	0.3	0.4	0.6	-0.8	-0.0	-0.8
Cu content in liver	3.8	4.7	5.8	2.4	-1.9	2.1
Fe content in liver	1.9	2.2	2.8	1.7	-1.3	1.5
K content in liver	0.1	0.1	0.2	0.3	-0.4	0.3
Mg content in liver	1.0	1.0	1.3	1.0	-1.1	0.8
Mn content in liver	0.8	0.9	1.1	-1.0	1.0	-0.8
Na content in liver	0.0	0.0	0.1	0.4	0.0	-0.0
Rb content in liver	1.2	1.5	1.9	0.9	-1.4	1.4
Se content in liver	0.5	0.6	0.9	0.5	-1.0	0.8
Sr content in liver	1.3	1.2	1.4	1.2	-1.2	0.8
Zn content in liver	2.7	3.0	3.4	1.8	-1.8	1.5
Bone: minimum diameter	0.5	0.9	1.3	1.1	-0.4	1.1
Time in familiar zone, hab. session 1	0.2	0.2	0.4	-0.4	0.6	-0.3
Time in novel zone, hab. session 1	1.4	1.4	1.5	1.2	-1.2	1.1
Total zone transitions, hab. session 1	2.3	3.3	4.2	-1.9	1.5	-2.0
Total locomotion distance, hab. session 1	0.2	0.3	0.7	-0.2	-0.2	-0.8
Locomotion velocity, hab. session 1	0.3	0.4	1.0	-0.3	-0.2	-1.0
Time in familiar zone, hab. session 2	3.6	3.7	4.0	2.0	-1.8	2.0
Time in novel zone, hab. session 2	2.9	2.9	3.6	-1.7	1.4	-1.9
Total zone transitions, hab. session 2	0.2	0.3	0.4	-0.5	0.6	-0.5
Total locomotion distance, hab. session 2	0.1	0.1	0.2	0.5	-0.4	0.1
Locomotion velocity, hab. session 2	0.0	0.0	0.1	0.1	-0.2	-0.3
Novel to familiar place preference ratio	1.0	1.0	1.8	-0.7	1.4	-0.9
Novelty place preference	1.2	1.3	2.1	-0.9	1.4	-1.0
Time in novel zone, NPP test	1.0	1.1	1.8	-0.8	1.3	-0.9
Total zone transitions, NPP test	0.1	0.1	0.2	-0.4	0.2	-0.5
Total locomotion distance, NPP test	0.2	0.2	0.5	0.5	-0.7	-0.0
Locomotion velocity, NPP test	0.2	0.3	0.6	0.6	-0.8	0.1
Intraocular pressure	3.9	5.4	6.8	-2.6	2.2	-2.1
Delta distance traveled before/after self-admin	0.8	0.8	1.2	1.1	-1.1	0.1
Delta ambulatory time before/after self-admin	0.8	0.9	1.6	1.3	-1.1	0.2
Parametrial fat weight	0.7	1.4	2.1	-1.0	1.0	-1.4
Pavlov. Cond. lever latency	0.1	0.1	0.2	0.5	-0.3	0.4
Pavlov. Cond. magazine entry latency	0.3	0.4	0.8	0.6	-0.2	0.9
Pavlov. Cond. change in total contacts	0.1	0.1	0.1	0.4	-0.4	0.4
Pavlov. Cond. index score	0.0	0.0	0.0	-0.0	0.0	0.1
Pavlov. Cond. latency score	0.0	0.0	0.0	-0.2	0.1	-0.2
Pavlov. Cond. lever contacts	0.0	0.0	0.0	0.1	-0.2	0.1
Pavlov. Cond. magazine entry number	0.2	0.3	0.4	-0.5	0.5	-0.6
Pavlov. Cond. intertrial magazine entries	0.1	0.1	0.2	0.2	-0.4	-0.1
Pavlov. Cond. lever-magazine prob. diff.	0.0	0.1	0.1	0.2	-0.2	0.3
Pavlov. Cond. response bias	0.1	0.1	0.2	0.3	-0.2	0.4
Pavlov. Cond. lever latency	0.7	1.0	1.5	-1.2	0.9	-0.8
Pavlov. Cond. magazine entry latency	0.1	0.1	0.3	0.2	-0.5	-0.1
Pavlov. Cond. change in total contacts	1.6	2.3	2.8	1.7	-1.6	1.2
Pavlov. Cond. index score	0.5	0.7	1.1	0.8	-1.0	0.5
Pavlov. Cond. latency score	0.5	0.6	1.0	0.8	-1.0	0.5
Pavlov. Cond. lever contacts	0.6	0.8	1.1	1.0	-0.9	0.7
Pavlov. Cond. magazine entry number	1.1	1.3	1.9	-1.1	1.4	-0.9
Pavlov. Cond. intertrial magazine entries	0.0	0.0	0.0	0.2	0.1	0.0
Pavlov. Cond. lever-magazine prob. diff.	0.6	0.7	1.2	0.9	-1.1	0.5
Pavlov. Cond. response bias	1.5	2.0	2.6	1.6	-1.4	1.2
Time in closed arm before self-admin	0.5	0.6	0.9	-0.8	1.0	-0.5
Time in closed arm after self-admin	1.3	1.3	1.5	-1.2	1.2	-1.1
Time in open arm before self-admin	0.1	0.1	0.2	0.0	-0.3	-0.4
Time in open arm after self-admin	0.3	0.3	0.6	0.3	-0.4	0.8
Bone: periosteal estimation	1.1	2.3	2.6	1.5	-1.4	1.6
Bone: periosteal perimeter	0.5	0.8	1.2	1.0	-0.6	1.1
Bone: post-yield work	0.1	0.1	0.2	0.4	-0.1	0.4
Progressive ratio test 1 active lever presses	0.4	0.4	0.8	-0.4	0.4	-0.9
Progressive ratio test 1 breakpoint	0.4	0.4	0.8	-0.4	0.4	-0.9
Progressive ratio test 1 inactive lever presses	0.1	0.1	0.3	0.1	-0.5	-0.3
Progressive ratio test 2 active lever presses	0.8	0.9	1.7	-0.7	0.7	-1.3
Progressive ratio test 2 breakpoint	1.0	1.1	2.0	-0.8	0.9	-1.4
Progressive ratio test 2 inactive lever presses	0.5	0.6	1.0	-0.8	0.5	-1.0
Incentive Sensitization - Responses	0.2	0.2	0.3	-0.4	0.4	-0.6
Incentive Sensitization - Breakpoint	0.2	0.2	0.4	-0.4	0.4	-0.6
Sum of active levers in priming session hrs 5-6	2.8	2.7	4.0	2.0	-1.8	1.0
Progressive ratio	0.0	0.0	0.1	0.3	-0.1	-0.2
Food seeking constrained by brief footshock	0.2	0.3	0.4	0.5	-0.5	0.6
Seeking ratio, punishment vs. effort	0.1	0.1	0.4	-0.0	-0.2	0.6
Retroperitoneal fat weight	3.5	11.6	12.3	-3.5	3.3	-3.3
Reaction time number correct	1.2	1.8	2.2	-1.5	1.2	-1.3
Reaction time mean minus median	0.5	0.6	0.8	0.9	-0.8	0.7
Reaction time mean minus median AUC	0.1	0.1	0.2	0.5	-0.1	-0.1
Reaction time num false alarms	0.6	0.8	1.5	-0.7	0.6	-1.2
Reaction time num false alarms AUC	1.1	1.5	2.6	-1.1	0.9	-1.6
Reaction time trials correct on left	1.2	1.8	2.2	-1.5	1.2	-1.3
Reaction time trials on left	1.3	1.8	2.2	-1.5	1.2	-1.3
Reaction time mean	0.1	0.2	0.3	-0.4	0.3	-0.5
Reaction time mean AUC	0.0	0.1	0.2	-0.1	-0.0	-0.4
Median of all reaction times	0.6	0.8	1.1	-0.8	0.7	-1.0
Reaction time omissions	0.1	0.1	0.2	0.3	-0.5	0.2
Reaction time false alarm rate	0.2	0.2	0.6	-0.2	0.3	-0.8
Reaction time premature initiation rate	1.4	1.8	3.1	1.2	-1.0	1.8
Reaction time premature initiations	0.3	0.5	1.0	0.5	-0.5	1.0
Std. dev. reaction times	0.0	0.0	0.1	0.0	0.1	-0.3
Reaction time trials completed	1.3	1.8	2.2	-1.5	1.2	-1.3
Reaction time trials AUC	1.2	1.8	2.1	-1.5	1.2	-1.3
Run reversals in cocaine runway, females	0.8	0.8	0.8	0.9	-0.9	0.9
Run reversals in cocaine runway, males	0.1	0.1	0.2	0.1	-0.4	0.3
Latency to leave start box in cocaine runway	1.7	1.8	2.2	1.5	-1.1	1.4
Latency to leave start box in cocaine runway, F	1.1	1.2	2.1	1.0	-0.7	1.5
Latency to leave start box in cocaine runway, M	0.1	0.1	0.2	0.5	-0.1	-0.2
Std. dev. time between licks in bursts	0.1	0.1	0.2	0.1	-0.4	0.2
Total sessions with >9 infusions	1.3	1.4	1.9	-1.1	1.0	-1.4
Short access day 1 total inactive lever presses	0.1	0.2	0.2	0.5	-0.4	-0.4
Short access day 10 total inactive lever presses	0.1	0.1	0.3	0.3	-0.2	0.6
Short access day 1 total infusions	0.4	0.4	1.3	-0.2	0.1	-1.1
Short access day 10 total infusions	0.0	0.0	0.0	0.1	0.1	-0.2
Short access total infusions	0.1	0.1	0.2	0.1	-0.2	-0.4
Short access day 1 locomotion	2.1	2.3	3.8	-1.2	1.3	-2.0
Short access day 10 total locomotion	2.0	2.2	3.0	-1.7	1.4	-1.3
Short access total locomotion	1.1	1.1	1.3	-1.1	1.0	-1.1
One hour access (0.3 mA shock)	0.4	0.5	0.7	-0.5	0.7	-0.8
Compulsive drug intake	0.4	0.4	0.6	-0.5	0.8	-0.7
One hour access (shock baseline)	0.0	0.0	0.1	-0.2	-0.1	-0.3
Social response proportion	0.4	0.4	0.6	-0.7	0.5	-0.6
Social responses	0.7	0.9	1.3	1.1	-1.1	0.5
Social time	0.1	0.2	0.3	-0.3	0.6	-0.2
Soleus weight	1.5	4.4	5.1	-2.3	2.2	-1.8
Bone: stiffness	0.7	1.1	1.5	1.0	-0.9	1.2
Tibialis anterior weight	1.0	3.6	4.5	-2.1	2.1	-1.4
Time to tail flick, vehicle, before self-admin	3.9	4.0	4.7	2.2	-1.7	2.1
Time to tail flick, vehicle, after self-admin	0.3	0.3	0.5	0.5	-0.7	0.5
Time to tail flick, test, before self-admin	0.3	0.3	0.7	-0.2	0.8	-0.4
Time to tail flick, test, after self-admin	0.6	0.7	1.0	1.0	-0.7	0.7
Delta time to tail flick, vehicle, before/after SA	1.0	1.0	1.5	-1.2	0.8	-0.9
Delta time to tail flick, test, before/after SA	0.2	0.2	0.3	0.4	-0.5	0.4
Tibia length	0.7	1.9	2.0	-1.4	1.4	-1.3
Ambulatory time before self-admin	0.1	0.1	0.3	0.6	-0.0	0.3
Ambulatory time after self-admin	0.5	0.5	1.4	1.2	-0.4	0.2
Bone: tissue strength	0.0	0.0	0.0	-0.0	0.2	-0.1
Total heroin consumption	0.1	0.1	0.2	0.1	-0.3	-0.4
Bone: trabecular number	0.1	0.1	0.1	0.3	-0.2	0.3
Bone: trabecular spacing	0.1	0.1	0.2	0.1	-0.3	0.5
Bone: trabecular thickness	0.1	0.1	0.3	0.4	-0.2	0.5
Bone: trabecular tissue density	0.0	0.1	0.1	-0.3	-0.1	0.2
Water consumed over 24 hours	0.1	0.1	0.1	0.4	0.3	0.2
Number of responses in last shaping day	0.3	0.3	0.7	0.4	-0.9	0.1