Hub : Traits : body_g : ← →

chr3:114,188,900-117,826,996

Best TWAS P=3.289043e-08 · Best GWAS P=2.968915e-08 conditioned to 1

Associated models

#	Tissue	Gene	Modality	RNA phenotype	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	Adipose	Snrpb	alternative polyA	ENSRNOT00000049857	0.16	0.17	blup	1800	0.18	4.2e-20	-5.2	5.1	3.2e-07	-0.98	0.58	0.42	FALSE
2	Adipose	Snrpb	alternative polyA	ENSRNOT00000079923	0.16	0.17	blup	1800	0.19	3.0e-20	-5.2	-5.1	3.1e-07	0.98	0.57	0.43	FALSE
3	Adipose	Snrpb	alternative polyA	ENSRNOT00000049857	0.15	0.16	blup	1800	0.18	1.1e-19	-5.2	5.1	3.3e-07	-0.98	0.59	0.41	FALSE
4	Adipose	Snrpb	alternative polyA	ENSRNOT00000079923	0.16	0.16	blup	1800	0.18	7.2e-20	-5.2	-5.1	3.2e-07	0.98	0.58	0.42	FALSE
5	Adipose	Cpxm1	gene expression	ENSRNOG00000021220	0.05	0.04	lasso	3	0.04	1.8e-05	-5.1	-5.2	2.1e-07	0.98	0.57	0.42	FALSE
6	Adipose	Pced1a	gene expression	ENSRNOG00000021221	0.09	0.08	top1	1	0.08	4.1e-09	-5.2	-5.2	1.7e-07	0.98	0.41	0.58	FALSE
7	Adipose	Mrps26	gene expression	ENSRNOG00000021224	0.04	0.01	top1	1	0.01	1.1e-02	-5.2	-5.2	1.8e-07	0.98	0.04	0.04	FALSE
8	Adipose	Ubox5	gene expression	ENSRNOG00000021230	0.09	0.07	top1	1	0.07	1.5e-08	-5.2	-5.2	1.7e-07	0.98	0.36	0.63	FALSE
9	Adipose	NA	gene expression	ENSRNOG00000068360	0.07	0.05	top1	1	0.05	6.8e-06	-5.4	5.4	7.1e-08	-0.98	0.17	0.58	FALSE
10	Adipose	Ptpra	intron excision ratio	chr3:117705569:117714664	0.02	0.01	top1	1	0.01	2.7e-02	-5.2	5.2	2.4e-07	-0.98	0.04	0.03	FALSE
11	Adipose	Ubox5	intron excision ratio	chr3:117833084:117846375	0.03	0.01	top1	1	0.01	2.0e-02	-5.1	5.1	2.6e-07	-0.98	0.03	0.03	FALSE
12	Adipose	AABR07053741.1	intron excision ratio	chr3:117833084:117846375	0.03	0.01	top1	1	0.01	2.0e-02	-5.1	5.1	2.6e-07	-0.98	0.03	0.03	FALSE
13	Adipose	Mal	mRNA stability	ENSRNOG00000015445	0.05	0.02	top1	1	0.02	9.0e-04	-5.2	5.2	1.9e-07	-0.90	0.05	0.12	FALSE
14	Adipose	Pced1a	mRNA stability	ENSRNOG00000021221	0.03	0.03	top1	1	0.03	6.5e-04	-5.2	-5.2	1.7e-07	0.98	0.06	0.06	FALSE
15	BLA	Mrps26	gene expression	ENSRNOG00000021224	0.12	0.04	blup	1026	0.05	9.2e-04	-5.4	-5.1	2.7e-07	0.98	0.43	0.49	FALSE
16	BLA	Ubox5	gene expression	ENSRNOG00000021230	0.17	0.06	top1	1	0.06	5.3e-04	-5.5	-5.5	3.3e-08	0.98	0.06	0.38	TRUE
17	BLA	NA	gene expression	ENSRNOG00000066318	0.24	0.20	blup	1487	0.20	3.9e-11	-5.0	5.1	3.1e-07	-0.98	0.58	0.42	FALSE
18	BLA	NA	gene expression	ENSRNOG00000068360	0.59	0.22	lasso	19	0.24	5.6e-13	-5.3	5.3	1.0e-07	-0.99	0.40	0.60	FALSE
19	BLA	Ubox5	intron excision ratio	chr3:117817986:117819831	0.75	0.50	top1	1	0.50	1.8e-30	-5.1	5.1	3.2e-07	-0.98	0.52	0.48	FALSE
20	BLA	Ubox5	intron excision ratio	chr3:117817986:117819882	0.76	0.49	top1	1	0.49	1.5e-29	-5.1	-5.1	3.2e-07	0.98	0.52	0.48	FALSE
21	BLA	Ubox5	intron excision ratio	chr3:117820001:117847621	0.12	0.05	top1	1	0.05	9.5e-04	-5.2	-5.2	2.4e-07	0.98	0.08	0.10	FALSE
22	BLA	AABR07053741.1	intron excision ratio	chr3:117820001:117847621	0.12	0.05	top1	1	0.05	9.5e-04	-5.2	-5.2	2.4e-07	0.98	0.08	0.10	FALSE
23	BLA	NA	mRNA stability	ENSRNOG00000068184	0.17	0.09	top1	1	0.09	1.3e-05	-5.3	-5.3	1.4e-07	0.93	0.17	0.47	FALSE
24	Brain	Snrpb	alternative polyA	ENSRNOT00000079923	0.09	0.09	blup	1800	0.10	3.8e-09	-5.2	-5.1	3.2e-07	0.98	0.57	0.43	FALSE
25	Brain	Zc3h6	alternative polyA	ENSRNOT00000024322	0.04	0.05	top1	1	0.05	2.8e-05	-5.3	5.3	1.4e-07	-0.92	0.08	0.09	FALSE
26	Brain	Zc3h6	alternative polyA	ENSRNOT00000108152	0.04	0.05	top1	1	0.05	2.8e-05	-5.3	-5.3	1.4e-07	0.92	0.08	0.09	FALSE
27	Brain	Ebf4	gene expression	ENSRNOG00000007408	0.18	0.18	top1	1	0.18	1.3e-16	-5.3	5.3	1.4e-07	-0.98	0.39	0.61	FALSE
28	Brain	Ptpra	gene expression	ENSRNOG00000021223	0.11	0.07	blup	1343	0.07	2.9e-07	-5.2	-5.1	3.0e-07	0.95	0.46	0.54	FALSE
29	Brain	Ubox5	gene expression	ENSRNOG00000021230	0.13	0.10	blup	815	0.11	1.0e-10	-5.2	-5.2	2.3e-07	0.98	0.45	0.55	FALSE
30	Brain	NA	gene expression	ENSRNOG00000066318	0.19	0.18	enet	21	0.19	5.9e-17	-5.1	5.3	1.3e-07	-0.99	0.42	0.58	FALSE
31	Brain	NA	gene expression	ENSRNOG00000068184	0.04	0.03	top1	1	0.03	1.3e-03	-5.2	5.2	2.0e-07	-0.91	0.07	0.05	FALSE
32	Brain	NA	gene expression	ENSRNOG00000068360	0.28	0.23	lasso	53	0.23	8.1e-21	-5.3	5.3	1.3e-07	-1.00	0.41	0.59	FALSE
33	Brain	Pced1a	isoform ratio	ENSRNOT00000055810	0.04	0.04	top1	1	0.04	1.2e-04	-5.2	-5.2	1.8e-07	0.98	0.10	0.10	FALSE
34	Brain	Pced1a	isoform ratio	ENSRNOT00000082369	0.04	0.04	top1	1	0.04	1.4e-04	-5.2	5.2	1.8e-07	-0.98	0.09	0.09	FALSE
35	Brain	Vps16	isoform ratio	ENSRNOT00000028821	0.02	0.02	enet	9	0.02	3.1e-03	-5.1	5.2	1.6e-07	-0.93	0.46	0.42	FALSE
36	Brain	Vps16	isoform ratio	ENSRNOT00000114809	0.02	0.01	blup	1438	0.02	3.8e-03	-5.1	-5.1	3.3e-07	0.98	0.45	0.44	FALSE
37	Brain	Zc3h8	intron excision ratio	chr3:116190795:116192573	0.16	0.12	top1	1	0.12	7.0e-11	-5.4	-5.4	6.8e-08	0.91	0.15	0.85	FALSE
38	Brain	Zc3h8	intron excision ratio	chr3:116190795:116193598	0.09	0.07	lasso	17	0.07	2.3e-07	-5.4	5.4	6.8e-08	-0.88	0.28	0.72	FALSE
39	Brain	Ubox5	intron excision ratio	chr3:117817986:117819831	0.88	0.78	blup	815	0.79	1.8e-116	-5.3	5.4	7.2e-08	-1.00	0.19	0.81	FALSE
40	Brain	Ubox5	intron excision ratio	chr3:117817986:117819882	0.86	0.75	enet	41	0.77	1.2e-108	-5.3	-5.4	6.4e-08	1.00	0.19	0.81	FALSE
41	Brain	NA	intron excision ratio	chr3:116408104:116408408	0.04	0.03	top1	1	0.03	6.7e-04	-5.2	5.2	2.2e-07	-0.94	0.09	0.08	FALSE
42	Brain	Ebf4	mRNA stability	ENSRNOG00000007408	0.19	0.21	top1	1	0.21	2.5e-19	-5.2	5.2	1.6e-07	-0.98	0.43	0.57	FALSE
43	Eye	NA	gene expression	ENSRNOG00000068360	0.35	0.16	top1	1	0.16	1.9e-03	-5.2	5.2	1.8e-07	-0.98	0.06	0.06	FALSE
44	Eye	Ubox5	intron excision ratio	chr3:117817986:117819831	0.76	0.23	lasso	18	0.24	1.5e-04	-5.3	5.2	1.9e-07	-0.99	0.34	0.52	FALSE
45	IL	Mall	gene expression	ENSRNOG00000015599	0.40	0.21	top1	1	0.21	1.1e-05	-5.3	-5.3	1.1e-07	0.91	0.09	0.19	FALSE
46	IL	Fbln7	gene expression	ENSRNOG00000017550	0.41	0.16	lasso	5	0.20	1.4e-05	-5.2	-5.1	2.8e-07	0.92	0.40	0.57	FALSE
47	IL	Ubox5	gene expression	ENSRNOG00000021230	0.16	0.08	top1	1	0.08	5.3e-03	-5.2	-5.2	1.8e-07	0.98	0.04	0.06	FALSE
48	IL	NA	gene expression	ENSRNOG00000068360	0.32	0.19	top1	1	0.19	2.9e-05	-5.1	5.1	2.9e-07	-0.98	0.09	0.09	FALSE
49	IL	Sirpa	isoform ratio	ENSRNOT00000095684	0.59	-0.01	lasso	10	-0.01	5.3e-01	-5.3	5.2	2.4e-07	-0.88	0.28	0.16	FALSE
50	LHb	Ttl	gene expression	ENSRNOG00000018205	0.27	0.05	top1	1	0.05	2.9e-02	-5.2	-5.2	1.7e-07	0.85	0.10	0.06	FALSE
51	LHb	Mrps26	gene expression	ENSRNOG00000021224	0.23	0.06	blup	1020	0.12	8.3e-04	-5.1	-5.1	3.0e-07	0.98	0.43	0.42	FALSE
52	Liver	Snrpb	alternative polyA	ENSRNOT00000079923	0.05	0.03	enet	18	0.03	1.1e-04	-5.1	-5.3	1.1e-07	0.89	0.57	0.41	FALSE
53	Liver	Mertk	gene expression	ENSRNOG00000017319	0.19	0.09	enet	172	0.11	2.5e-12	5.0	5.2	2.1e-07	-0.84	0.45	0.55	FALSE
54	Liver	Ubox5	gene expression	ENSRNOG00000021230	0.14	0.11	blup	815	0.12	9.1e-13	-4.9	-5.1	2.7e-07	0.98	0.45	0.55	FALSE
55	Liver	AABR07053741.1	gene expression	ENSRNOG00000053270	0.03	0.00	blup	813	0.01	6.9e-02	-5.2	5.2	2.5e-07	-0.98	0.26	0.33	FALSE
56	Liver	NA	gene expression	ENSRNOG00000067465	0.17	0.15	top1	1	0.15	2.1e-16	-5.3	5.3	1.4e-07	-0.91	0.42	0.58	FALSE
57	Liver	Zc3h8	intron excision ratio	chr3:116190795:116192573	0.04	0.00	top1	1	0.00	8.7e-02	-5.2	-5.2	1.7e-07	0.88	0.06	0.04	FALSE
58	Liver	Zc3h8	intron excision ratio	chr3:116190795:116193598	0.07	0.04	top1	1	0.04	7.7e-05	-5.2	5.2	2.2e-07	-0.91	0.12	0.14	FALSE
59	Liver	Ubox5	intron excision ratio	chr3:117817986:117819831	0.71	0.36	enet	25	0.37	3.7e-43	-5.3	5.4	7.5e-08	-0.99	0.37	0.63	FALSE
60	Liver	Ubox5	intron excision ratio	chr3:117817986:117819882	0.70	0.36	enet	25	0.37	8.3e-43	-5.3	-5.4	7.6e-08	0.99	0.37	0.63	FALSE
61	NAcc	NA	gene expression	ENSRNOG00000066318	0.31	0.21	enet	8	0.21	1.8e-05	-5.1	5.1	3.1e-07	-0.98	0.53	0.44	FALSE
62	NAcc	NA	gene expression	ENSRNOG00000068360	0.26	0.09	blup	946	0.10	2.6e-03	-5.3	5.1	3.0e-07	-0.98	0.36	0.38	FALSE
63	NAcc2	Ebf4	gene expression	ENSRNOG00000007408	0.07	0.02	blup	1633	0.04	3.1e-03	-5.2	5.1	3.1e-07	-0.96	0.50	0.40	FALSE
64	NAcc2	Slc20a1	gene expression	ENSRNOG00000018567	0.16	0.06	top1	1	0.06	2.3e-04	-5.3	-5.3	1.4e-07	0.94	0.09	0.07	FALSE
65	NAcc2	Ubox5	gene expression	ENSRNOG00000021230	0.07	0.03	blup	815	0.04	2.7e-03	-5.1	-5.1	2.9e-07	0.98	0.43	0.47	FALSE
66	NAcc2	NA	gene expression	ENSRNOG00000066318	0.17	0.14	blup	1487	0.15	1.2e-08	-4.7	5.1	2.9e-07	-0.97	0.55	0.45	FALSE
67	NAcc2	NA	gene expression	ENSRNOG00000068360	0.16	0.12	top1	1	0.12	4.7e-07	-5.2	5.2	2.4e-07	-0.98	0.44	0.48	FALSE
68	NAcc2	Stk35	intron excision ratio	chr3:117019469:117044703	0.05	0.02	top1	1	0.02	1.9e-02	-5.1	5.1	2.9e-07	-0.97	0.09	0.04	FALSE
69	NAcc2	Zc3h8	intron excision ratio	chr3:116190795:116193598	0.08	0.04	blup	2189	0.04	3.3e-03	-4.8	5.1	2.9e-07	-0.92	0.37	0.50	FALSE
70	NAcc2	Zc3h8	intron excision ratio	chr3:116192760:116193598	0.11	0.05	top1	1	0.05	1.6e-03	-5.3	-5.3	1.4e-07	0.89	0.09	0.05	FALSE
71	NAcc2	Ubox5	intron excision ratio	chr3:117817986:117819831	0.49	0.45	lasso	21	0.46	3.5e-27	-5.1	5.1	3.1e-07	-0.98	0.50	0.50	FALSE
72	NAcc2	Tmem87b	mRNA stability	ENSRNOG00000017443	0.06	0.03	enet	3	0.04	5.2e-03	5.0	5.2	2.5e-07	-0.53	0.42	0.43	FALSE
73	NAcc2	Pced1a	mRNA stability	ENSRNOG00000021221	0.09	0.07	blup	1437	0.08	6.6e-05	-5.3	-5.1	2.8e-07	0.98	0.53	0.46	FALSE
74	OFC	Snrpb	alternative polyA	ENSRNOT00000049857	0.22	0.15	top1	1	0.15	1.7e-04	-5.1	5.1	3.0e-07	-0.98	0.11	0.06	FALSE
75	OFC	Snrpb	alternative polyA	ENSRNOT00000079923	0.23	0.16	top1	1	0.16	1.1e-04	-5.1	-5.1	3.0e-07	0.98	0.11	0.07	FALSE
76	OFC	Snrpb	gene expression	ENSRNOG00000006961	0.12	0.10	top1	1	0.10	2.0e-03	-5.1	5.1	2.8e-07	-0.98	0.09	0.05	FALSE
77	OFC	Mall	gene expression	ENSRNOG00000015599	0.23	0.13	top1	1	0.13	5.5e-04	-5.3	-5.3	1.4e-07	0.91	0.07	0.07	FALSE
78	OFC	Nphp1	gene expression	ENSRNOG00000015756	0.21	0.13	top1	1	0.13	5.3e-04	-5.3	5.3	1.4e-07	-0.91	0.07	0.06	FALSE
79	OFC	Zc3h6	gene expression	ENSRNOG00000026277	0.28	0.08	top1	1	0.08	7.1e-03	-5.2	5.2	1.8e-07	-0.89	0.11	0.06	FALSE
80	OFC	NA	gene expression	ENSRNOG00000068360	0.37	0.24	blup	948	0.26	8.6e-07	-5.1	5.1	2.7e-07	-0.98	0.48	0.52	FALSE
81	PL	Fbln7	gene expression	ENSRNOG00000017550	0.47	0.22	lasso	8	0.24	2.0e-06	-5.3	-5.2	1.6e-07	0.90	0.36	0.63	FALSE
82	PL	Ttl	gene expression	ENSRNOG00000018205	0.80	0.05	lasso	6	0.10	2.2e-03	4.4	5.1	2.8e-07	-0.82	0.38	0.36	FALSE
83	PL	Itpa	isoform ratio	ENSRNOT00000112870	0.19	0.09	top1	1	0.09	4.6e-03	-5.1	5.1	2.9e-07	-0.98	0.04	0.06	FALSE
84	PL	Ttl	mRNA stability	ENSRNOG00000018205	0.23	0.07	lasso	1	0.07	9.0e-03	-5.2	5.2	1.7e-07	-0.89	0.26	0.44	FALSE
85	PL2	Snrpb	alternative polyA	ENSRNOT00000079923	0.20	0.17	top1	1	0.17	1.6e-09	-5.2	-5.2	2.6e-07	0.98	0.56	0.44	FALSE
86	PL2	Snrpb	alternative polyA	ENSRNOT00000079923	0.26	0.17	top1	1	0.17	1.5e-09	-5.2	-5.2	2.6e-07	0.98	0.56	0.44	FALSE
87	PL2	Pced1a	alternative TSS	ENSRNOT00000055810	0.04	0.02	top1	1	0.02	2.4e-02	-5.3	-5.3	1.4e-07	0.98	0.06	0.04	FALSE
88	PL2	Zc3h6	gene expression	ENSRNOG00000026277	0.07	0.05	top1	1	0.05	7.7e-04	-5.2	5.2	1.6e-07	-0.91	0.09	0.05	FALSE
89	PL2	NA	gene expression	ENSRNOG00000068184	0.32	0.21	enet	160	0.28	1.1e-15	4.1	5.2	1.6e-07	-0.85	0.42	0.58	FALSE
90	PL2	NA	gene expression	ENSRNOG00000068360	0.74	0.13	lasso	18	0.14	3.4e-08	-5.2	5.4	7.2e-08	-0.99	0.33	0.67	FALSE
91	PL2	Snrpb	isoform ratio	ENSRNOT00000118374	0.09	0.09	top1	1	0.09	9.4e-06	-5.1	5.1	3.0e-07	-0.98	0.21	0.14	FALSE
92	PL2	Zc3h8	intron excision ratio	chr3:116190795:116193598	0.21	0.17	top1	1	0.17	2.5e-09	-5.4	5.4	6.8e-08	-0.91	0.15	0.85	FALSE
93	PL2	Ubox5	intron excision ratio	chr3:117817986:117819831	0.73	0.53	enet	37	0.55	9.2e-35	-5.3	5.3	9.6e-08	-0.99	0.30	0.70	FALSE
94	PL2	Ubox5	intron excision ratio	chr3:117817986:117819882	0.73	0.53	lasso	30	0.55	5.6e-35	-5.3	-5.4	6.7e-08	0.99	0.29	0.71	FALSE
95	PL2	Pced1a	mRNA stability	ENSRNOG00000021221	0.16	0.17	enet	67	0.17	1.4e-09	-5.2	-5.2	2.0e-07	0.99	0.54	0.46	FALSE

h2: Heritability estimate for the given transcriptomic model. PP3: Posterior probability of two distinct causal variants. PP4: Posterior probability of a single shared causal variant. joint: Whether the RNA phenotype is in the joint model.