chr3:114,120,424-117,823,761

Trait: Body weight

Best TWAS P=3.45e-08 · Best GWAS P=2.97e-08 conditioned to 1.00e+00

Associated models

Tissue Gene RNA modality RNA phenotype h2 # weights Model R2 Model R2 P TWAS Z TWAS P Coloc P Joint
Adipose Snrpb alternative polyA NM_134358.1 0.15 37 0.17 2.2e-18 5.28 1.31e-07 0.42 FALSE
Adipose Snrpb alternative polyA XM_039104198.1 0.15 37 0.17 7.7e-19 -5.28 1.26e-07 0.42 FALSE
Adipose Zc3h6 alternative TSS NM_001107772.1 0.04 1 0.02 4.8e-03 -5.23 1.70e-07 0.03 FALSE
Adipose Cpxm1 gene expression Cpxm1 0.05 1 0.05 2.5e-06 5.39 7.13e-08 0.66 FALSE
Adipose LOC129351010 gene expression LOC129351010 0.03 1 0.02 3.1e-03 -5.39 7.13e-08 0.05 FALSE
Adipose Mrps26 gene expression Mrps26 0.04 1 0.02 5.5e-03 5.2 1.97e-07 0.04 FALSE
Adipose Nop56 gene expression Nop56 0.03 1 0.02 3.6e-03 -5.2 2.04e-07 0.04 FALSE
Adipose Pced1a gene expression Pced1a 0.03 1 0.02 1.4e-03 5.2 1.95e-07 0.04 FALSE
Adipose Ubox5 gene expression Ubox5 0.11 1 0.08 6.6e-09 5.39 7.13e-08 0.8 FALSE
Adipose Zc3h6 gene expression Zc3h6 0.12 1 0.06 9.7e-07 -5.23 1.70e-07 0.63 FALSE
Adipose Snrpb isoform ratio NM_134358.1 0.15 4 0.16 1.5e-17 -5.39 6.85e-08 0.42 FALSE
Adipose Snrpb isoform ratio XM_039104198.1 0.16 17 0.17 9.0e-19 5.34 9.29e-08 0.42 FALSE
Adipose Zc3h6 isoform ratio XM_006234999.4 0.06 1 0.03 1.7e-04 -5.23 1.70e-07 0.12 FALSE
Adipose Zc3h6 isoform ratio XM_039104996.1 0.07 1 0.03 1.2e-04 5.23 1.70e-07 0.1 FALSE
Adipose Fastkd5 intron excision ratio chr3_117833084_117846375 0.03 1 0.01 2.5e-02 -5.2 1.98e-07 0.03 FALSE
Adipose Ptpra intron excision ratio chr3_117705569_117714664 0.02 1 0.01 7.1e-02 -5.2 1.97e-07 0.03 FALSE
Adipose Ubox5 intron excision ratio chr3_117833084_117846375 0.03 1 0.01 2.5e-02 -5.2 1.98e-07 0.03 FALSE
Adipose Ubox5 mRNA stability Ubox5 0.04 1 0.03 7.4e-04 5.39 7.13e-08 0.08 FALSE
Adipose Zc3h6 mRNA stability Zc3h6 0.12 1 0.06 1.5e-07 -5.23 1.70e-07 0.69 FALSE
BLA Zc3h6 alternative polyA NM_001107772.1 0.2 1 0.13 2.1e-07 5.3 1.16e-07 0.73 FALSE
BLA Zc3h6 alternative polyA XM_039104996.1 0.2 1 0.13 3.3e-07 -5.3 1.16e-07 0.71 FALSE
BLA Zc3h6 alternative polyA NM_001107772.1 0.2 1 0.13 2.3e-07 5.3 1.16e-07 0.73 FALSE
BLA Zc3h6 alternative polyA XM_006234999.4 0.19 1 0.12 3.8e-07 -5.3 1.16e-07 0.71 FALSE
BLA Bcl2l11 gene expression Bcl2l11 0.06 1671 0.03 9.6e-03 5.24 1.59e-07 0.39 FALSE
BLA LOC103691888 gene expression LOC103691888 0.34 1 0.2 8.9e-11 -5.27 1.36e-07 0.66 FALSE
BLA Mrps26 gene expression Mrps26 0.14 1 0.06 4.3e-04 5.49 4.10e-08 0.16 FALSE
BLA Pced1a gene expression Pced1a 0.19 1 0.16 4.2e-09 -5.39 7.13e-08 0.76 FALSE
BLA Ubox5 gene expression Ubox5 0.68 1 0.1 5.0e-06 5.2 2.04e-07 0.47 FALSE
BLA Pced1a isoform ratio XM_039104578.1 0.22 1 0.2 9.2e-11 -5.39 7.13e-08 0.76 FALSE
BLA Zc3h6 isoform ratio XM_039104996.1 0.1 1 0.04 5.8e-03 5.18 2.22e-07 0.06 FALSE
BLA Fastkd5 intron excision ratio chr3_117820001_117847621 0.13 1 0.07 1.3e-04 5.2 1.98e-07 0.12 FALSE
BLA Ubox5 intron excision ratio chr3_117817986_117819831 0.87 816 0.51 4.2e-31 5.26 1.43e-07 0.75 FALSE
BLA Ubox5 intron excision ratio chr3_117817986_117819882 0.86 816 0.51 4.8e-31 -5.26 1.43e-07 0.75 FALSE
BLA Ubox5 intron excision ratio chr3_117820001_117847621 0.13 1 0.07 1.3e-04 5.2 1.98e-07 0.12 FALSE
BLA Bcl2l11 mRNA stability Bcl2l11 0.07 1 0.04 2.5e-03 5.43 5.63e-08 0.07 FALSE
BLA Vinac1 mRNA stability Vinac1 0.16 1 0.11 3.0e-06 5.3 1.16e-07 0.47 FALSE
Brain Snrpb alternative polyA NM_134358.1 0.11 11 0.13 9.7e-12 5.34 9.23e-08 0.44 FALSE
Brain Snrpb alternative polyA XM_039104198.1 0.11 13 0.13 8.2e-12 -5.32 1.01e-07 0.43 FALSE
Brain LOC103691888 gene expression LOC103691888 0.27 25 0.26 4.8e-24 -5.23 1.67e-07 0.55 FALSE
Brain Mrps26 gene expression Mrps26 0.2 1 0.17 1.9e-15 5.2 1.97e-07 0.56 FALSE
Brain Pced1a gene expression Pced1a 0.05 3 0.05 1.1e-05 5.21 1.86e-07 0.54 FALSE
Brain Ttl gene expression Ttl 0.06 1 0.03 1.0e-03 -5.2 2.04e-07 0.12 FALSE
Brain Ubox5 gene expression Ubox5 0.15 1 0.15 1.5e-13 5.22 1.78e-07 0.62 FALSE
Brain Vinac1 gene expression Vinac1 0.05 1 0.03 6.1e-04 -5.24 1.60e-07 0.15 FALSE
Brain Pced1a isoform ratio NM_001399285.1 0.07 2 0.09 2.0e-08 -5.22 1.81e-07 0.53 FALSE
Brain Snrpb isoform ratio NM_134358.1 0.14 17 0.14 6.7e-13 5.35 8.76e-08 0.49 FALSE
Brain Snrpb isoform ratio XM_039104198.1 0.14 16 0.13 2.2e-12 -5.38 7.56e-08 0.49 FALSE
Brain Vinac1 isoform ratio XM_039106562.1 0.06 1 0.04 1.6e-04 -5.29 1.25e-07 0.4 FALSE
Brain Vinac1 isoform ratio XM_039106563.1 0.06 1 0.04 2.5e-04 5.29 1.25e-07 0.4 FALSE
Brain LOC102549592 intron excision ratio chr3_116408104_116408408 0.03 1 0.02 2.9e-03 -5.24 1.60e-07 0.07 FALSE
Brain Ubox5 intron excision ratio chr3_117817986_117819831 0.93 71 0.77 7.8e-110 -5.39 6.96e-08 0.8 FALSE
Brain Ubox5 intron excision ratio chr3_117817986_117819882 0.94 78 0.76 2.4e-106 5.39 7.04e-08 0.8 FALSE
Brain Zc3h8 intron excision ratio chr3_116190795_116192573 0.14 1 0.12 1.3e-11 5.4 6.80e-08 0.85 FALSE
Brain Zc3h8 intron excision ratio chr3_116190795_116193598 0.1 35 0.08 4.7e-08 -5.28 1.31e-07 0.72 FALSE
Brain Ebf4 mRNA stability Ebf4 0.19 1 0.2 4.7e-18 -5.26 1.42e-07 0.6 FALSE
Brain Vps16 mRNA stability Vps16 0.04 1 0.03 5.7e-04 -5.39 7.13e-08 0.06 FALSE
Eye Ubox5 intron excision ratio chr3_117817986_117819831 0.86 1 0.39 4.4e-07 -5.17 2.28e-07 0.08 FALSE
Eye Ubox5 intron excision ratio chr3_117817986_117819882 0.85 1 0.39 5.4e-07 5.17 2.28e-07 0.08 FALSE
IL Mall gene expression Mall 0.45 1 0.19 2.0e-05 5.31 1.07e-07 0.16 FALSE
LHb LOC100909998 gene expression LOC100909998 0.28 1 0.06 1.5e-02 5.34 9.32e-08 0.06 FALSE
LHb Tgm6 gene expression Tgm6 0.24 2 0.17 7.3e-05 -5.2 1.96e-07 0.37 FALSE
Liver Snrpb alternative polyA NM_134358.1 0.14 14 0.14 8.2e-15 5.42 5.94e-08 0.44 FALSE
Liver Snrpb alternative polyA XM_039104198.1 0.16 20 0.15 5.6e-16 -5.32 1.01e-07 0.49 FALSE
Liver Fastkd5 gene expression Fastkd5 0.02 1 0.01 2.4e-02 -5.39 7.13e-08 0.03 FALSE
Liver LOC108350462 gene expression LOC108350462 0.02 1 0.01 9.6e-03 -5.39 7.13e-08 0.03 FALSE
Liver Snrpb gene expression Snrpb 0.04 1 0.02 1.9e-03 5.2 1.94e-07 0.04 FALSE
Liver Zc3h8 isoform ratio XM_039104994.1 0.04 1 0.02 2.5e-03 5.25 1.49e-07 0.04 FALSE
Liver Ubox5 intron excision ratio chr3_117816374_117817892 0.02 1 0.02 4.8e-03 -5.2 1.97e-07 0.03 FALSE
Liver Ubox5 intron excision ratio chr3_117817986_117819831 0.68 1 0.35 1.1e-40 -5.32 1.04e-07 0.73 FALSE
Liver Ubox5 intron excision ratio chr3_117817986_117819882 0.67 1 0.35 1.8e-40 5.32 1.04e-07 0.73 FALSE
Liver Zc3h8 intron excision ratio chr3_116190795_116192573 0.04 30 0.02 6.3e-03 5.22 1.84e-07 0.54 FALSE
Liver Zc3h8 intron excision ratio chr3_116190795_116193598 0.08 1 0.04 5.8e-05 -5.23 1.70e-07 0.22 FALSE
Liver Pced1a mRNA stability Pced1a 0.02 1 0.01 1.1e-02 5.2 1.95e-07 0.03 FALSE
NAcc Zc3h6 alternative polyA NM_001107772.1 0.24 25 0.18 6.8e-20 -5.25 1.50e-07 0.72 FALSE
NAcc Zc3h6 alternative polyA XM_039104996.1 0.24 28 0.18 8.0e-20 5.24 1.59e-07 0.71 FALSE
NAcc Zc3h6 alternative polyA NM_001107772.1 0.23 48 0.17 1.9e-19 -5.26 1.44e-07 0.72 FALSE
NAcc Zc3h6 alternative polyA XM_006234999.4 0.23 34 0.17 9.3e-20 5.25 1.56e-07 0.71 FALSE
NAcc Vinac1 alternative TSS XM_039106562.1 0.04 1 0.03 2.0e-04 -5.29 1.25e-07 0.16 FALSE
NAcc Mrps26 gene expression Mrps26 0.76 11 0.13 1.0e-14 -5.33 1.01e-07 0.76 FALSE
NAcc Pced1a gene expression Pced1a 0.14 1 0.08 4.1e-09 -5.19 2.07e-07 0.53 FALSE
NAcc Ptpra gene expression Ptpra 0.07 18 0.08 1.0e-09 -5.2 2.04e-07 0.44 FALSE
NAcc Slc20a1 gene expression Slc20a1 0.05 1 0.04 4.8e-05 5.21 1.93e-07 0.45 FALSE
NAcc Zc3h6 gene expression Zc3h6 0.2 1 0.04 5.8e-06 -5.35 8.87e-08 0.75 FALSE
NAcc Zc3h6 isoform ratio XM_039104996.1 0.24 1 0.11 1.0e-12 5.3 1.16e-07 0.77 FALSE
NAcc Fastkd5 intron excision ratio chr3_117820001_117847621 0.02 816 0.01 7.1e-03 -5.18 2.18e-07 0.5 FALSE
NAcc Ubox5 intron excision ratio chr3_117817986_117819831 0.49 816 0.53 1.7e-71 5.22 1.82e-07 0.58 FALSE
NAcc Ubox5 intron excision ratio chr3_117820001_117847621 0.02 816 0.01 7.1e-03 -5.18 2.18e-07 0.5 FALSE
NAcc Zc3h8 intron excision ratio chr3_116190795_116193598 0.11 1 0.1 2.3e-11 -5.3 1.16e-07 0.77 FALSE
NAcc Zc3h8 mRNA stability Zc3h8 0.04 1 0.02 2.2e-03 5.4 6.80e-08 0.09 FALSE
OFC Pdyn gene expression Pdyn 0.56 421 0.47 1.1e-12 -5.42 6.07e-08 0.48 FALSE
OFC Zc3h8 intron excision ratio chr3_116190795_116192573 0.31 1 0.19 2.4e-05 5.23 1.71e-07 0.08 FALSE
OFC Zc3h8 intron excision ratio chr3_116190795_116193598 0.32 1 0.2 2.1e-05 -5.23 1.71e-07 0.08 FALSE
OFC Ebf4 mRNA stability Ebf4 0.18 1 0.09 3.9e-03 -5.2 1.99e-07 0.05 FALSE
OFC Pced1a mRNA stability Pced1a 0.22 82 0.14 2.8e-04 5.19 2.14e-07 0.41 FALSE
PL LOC108350462 alternative polyA XR_005502459.1 0.03 1 0.02 1.6e-03 5.39 7.13e-08 0.06 FALSE
PL Pced1a alternative polyA XM_039104578.1 0.69 46 0.26 5.6e-29 5.2 1.98e-07 0.54 FALSE
PL Zc3h6 alternative polyA NM_001107772.1 0.11 1 0.09 8.6e-10 5.28 1.27e-07 0.76 FALSE
PL Zc3h6 alternative polyA XM_006234999.4 0.1 1 0.09 1.0e-09 -5.28 1.27e-07 0.76 FALSE
PL Zc3h6 alternative TSS NM_001107772.1 0.16 17 0.09 1.1e-09 5.33 9.71e-08 0.72 FALSE
PL Zc3h6 alternative TSS XM_039104996.1 0.06 1 0.04 2.1e-05 5.3 1.16e-07 0.46 FALSE
PL Cpxm1 gene expression Cpxm1 0.02 1 0.03 6.8e-04 -5.2 1.96e-07 0.04 FALSE
PL LOC103691888 gene expression LOC103691888 0.31 951 0.15 1.1e-15 5.22 1.81e-07 0.6 FALSE
PL Mrps26 gene expression Mrps26 0.26 19 0.13 3.6e-14 5.26 1.43e-07 0.67 FALSE
PL Pced1a gene expression Pced1a 0.12 4 0.1 4.5e-11 5.42 5.88e-08 0.65 FALSE
PL Ubox5 gene expression Ubox5 0.12 816 0.15 6.2e-16 -5.18 2.20e-07 0.56 FALSE
PL Zc3h6 gene expression Zc3h6 0.04 1 0.01 7.8e-03 -5.35 8.87e-08 0.16 FALSE
PL Pced1a isoform ratio NM_001399285.1 0.07 7 0.06 2.8e-07 -5.22 1.81e-07 0.51 FALSE
PL Pced1a isoform ratio XM_039104578.1 0.55 102 0.29 1.3e-31 -5.28 1.26e-07 0.54 FALSE
PL Cpxm1 intron excision ratio chr3_117601886_117617729 0.03 1 0.03 1.2e-04 -5.39 7.13e-08 0.23 FALSE
PL Pced1a intron excision ratio chr3_117601886_117617729 0.03 1 0.03 1.2e-04 -5.39 7.13e-08 0.24 FALSE
PL Ubox5 intron excision ratio chr3_117817986_117819831 0.58 816 0.62 1.1e-87 5.36 8.22e-08 0.8 FALSE
PL Ubox5 intron excision ratio chr3_117817986_117819882 0.55 816 0.6 4.0e-83 -5.33 9.66e-08 0.79 FALSE
PL Zc3h8 intron excision ratio chr3_116190795_116193598 0.16 1 0.15 8.7e-16 -5.24 1.60e-07 0.71 FALSE
PL Pced1a mRNA stability Pced1a 0.21 8 0.16 2.1e-17 -5.26 1.42e-07 0.54 FALSE
pVTA Pced1a alternative polyA NM_001399286.1 0.14 59 0.09 8.5e-05 5.28 1.31e-07 0.51 FALSE
pVTA Pced1a alternative polyA XM_039104578.1 0.15 1 0.1 4.2e-05 -5.22 1.78e-07 0.24 FALSE
pVTA Pced1a alternative TSS NM_001399286.1 0.07 7 0.09 8.5e-05 5.25 1.56e-07 0.45 FALSE
pVTA Pced1a alternative TSS NM_001399286.1 0.06 5 0.09 1.4e-04 -5.25 1.56e-07 0.43 FALSE
pVTA Fbln7 gene expression Fbln7 0.13 111 0.11 1.9e-05 5.23 1.72e-07 0.62 FALSE
pVTA LOC103691888 gene expression LOC103691888 0.87 1 0.14 1.6e-06 -5.52 3.45e-08 0.84 TRUE
pVTA Mrps26 gene expression Mrps26 0.3 57 0.19 1.7e-08 5.24 1.59e-07 0.59 FALSE
pVTA Ptpra gene expression Ptpra 0.08 6 0.1 6.9e-05 5.22 1.84e-07 0.44 FALSE
pVTA Pced1a isoform ratio XM_039104578.1 0.1 1 0.06 1.2e-03 -5.2 1.97e-07 0.13 FALSE
pVTA Ubox5 intron excision ratio chr3_117817986_117819831 0.81 76 0.65 1.9e-36 -5.26 1.41e-07 0.65 FALSE
pVTA Ubox5 intron excision ratio chr3_117817986_117819882 0.84 62 0.66 1.6e-37 5.27 1.40e-07 0.66 FALSE
pVTA Pced1a mRNA stability Pced1a 0.11 1 0.08 3.0e-04 5.24 1.61e-07 0.08 FALSE
RMTg Ubox5 gene expression Ubox5 0.3 1 0.12 4.4e-04 5.22 1.82e-07 0.06 FALSE