LOC120093830

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 pVTA alternative TSS XR_005487584.1 0.13 0.11 1.5e-04 0.09 0.08 0.09 0.11 1.5e-04 2.5e-04 9.5e-05 1.7e-05
2 pVTA alternative TSS XR_005487585.1 0.11 0.1 3.4e-04 0.08 0.07 0.08 0.08 3.1e-04 5.3e-04 1.8e-04 2.7e-04
3 PL isoform ratio XR_005487584.1 0.03 0.03 8.1e-04 0.02 0.02 0.02 0.02 2.1e-03 2.0e-03 2.0e-03 2.2e-03
4 Adipose alternative TSS XR_005487585.1 0.03 0.04 6.1e-04 0.02 0.02 0.01 0.02 3.2e-03 2.2e-03 7.5e-03 4.2e-03
5 Adipose alternative TSS XR_005487584.1 0.03 0.04 6.0e-04 0.02 0.02 0.02 0.02 3.0e-03 2.3e-03 5.0e-03 4.1e-03
6 NAcc isoform ratio XR_005487584.1 0.13 0.11 2.1e-14 0.12 0.11 0.1 0.11 3.2e-13 8.0e-13 1.5e-11 3.7e-13
7 NAcc alternative TSS XR_005487584.1 0.12 0.12 8.7e-12 0.09 0.1 0.09 0.1 8.4e-11 4.2e-11 4.8e-11 2.8e-11
8 NAcc alternative TSS XR_005487585.1 0.11 0.11 1.1e-10 0.08 0.08 0.08 0.08 1.4e-09 7.4e-10 1.6e-09 6.2e-10
9 pVTA isoform ratio XR_005487584.1 0.12 0.08 2.6e-05 0.12 0.12 0.11 0.11 9.2e-06 1.2e-05 1.7e-05 1.3e-05
10 Liver gene expression LOC120093830 0.05 0.05 5.7e-05 0.04 0.03 0.03 0.03 8.9e-05 4.6e-04 1.9e-04 4.0e-04

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10
Bone: apparent density10.617.719.4-4.3-4.3-4.2-4.24.24.4-4.14.14.3-4.0
Area under the delay curve0.91.01.3-1.0-1.2-1.0-1.01.01.0-0.90.91.0-0.9
BMI with tail4.614.816.9-3.8-3.9-3.8-3.83.83.5-4.14.13.6-4.1
BMI without tail0.00.10.30.20.00.20.1-0.1-0.3-0.30.3-0.3-0.5
Body weight6.427.030.4-5.1-5.3-5.1-5.15.14.8-5.55.55.0-5.5
Weight adjusted by age2.22.53.3-1.5-1.5-1.5-1.51.51.5-1.81.81.5-1.8
Bone surface12.421.923.7-4.8-4.7-4.7-4.74.74.9-4.64.64.7-4.5
Bone volume9.215.717.1-4.1-4.0-4.0-4.04.04.1-3.83.84.1-3.7
Breakpoint value in progressive ratio session0.20.20.3-0.4-0.4-0.5-0.50.50.5-0.60.60.3-0.6
Number of licking bursts0.30.40.70.60.60.70.7-0.7-0.80.3-0.3-0.70.1
Context. condit. distance diff. score0.30.30.6-0.5-0.5-0.5-0.50.50.3-0.70.70.5-0.8
Locomotion velocity, session 11.21.31.81.11.01.01.1-1.1-0.91.3-1.3-1.01.3
Locomotion distance, session 13.24.05.71.91.91.91.9-1.9-1.72.3-2.3-1.92.4
Locomotion velocity, session 20.40.41.20.40.30.50.5-0.5-0.31.0-1.0-0.41.1
Locomotion distance, session 22.63.65.41.81.71.81.8-1.8-1.62.2-2.2-1.72.3
Locomotion velocity, session 34.14.85.42.12.12.22.2-2.2-2.02.3-2.3-2.12.3
Locomotion distance, session 35.15.66.22.32.42.42.4-2.4-2.12.5-2.5-2.22.4
Stereotopy head waving bouts, day 31.11.41.9-1.3-1.4-1.2-1.21.21.3-0.90.91.3-0.8
Stereotopy head waving duration, day 30.50.61.0-0.9-1.0-0.9-0.90.80.9-0.40.40.9-0.2
Locomotion velocity, session 70.20.20.30.40.50.50.5-0.5-0.40.5-0.5-0.40.4
Locomotion distance, session 71.51.92.41.41.51.51.5-1.5-1.41.2-1.2-1.41.1
Stereotopy head waving bouts, day 71.01.11.5-1.1-1.2-1.0-1.01.01.2-0.90.91.1-0.9
Stereotopy head waving duration, day 71.21.41.8-1.2-1.4-1.2-1.21.21.3-1.11.11.2-1.1
Locomotion velocity, session 80.00.00.1-0.0-0.2-0.1-0.10.1-0.00.2-0.20.00.3
Locomotion distance, session 81.21.72.11.31.31.31.3-1.3-1.21.4-1.4-1.21.4
Degree of sensitization distance0.60.60.9-0.7-0.7-0.7-0.70.70.5-0.90.90.6-0.9
Degree of sensitization stereotypy0.20.20.3-0.4-0.5-0.4-0.40.40.5-0.40.40.4-0.5
Conditioned locomotion0.00.00.1-0.2-0.2-0.2-0.20.20.3-0.00.00.30.0
Cocaine response after cond. corrected0.00.00.10.0-0.00.10.1-0.1-0.00.2-0.2-0.10.2
Cocaine response after cond. not corrected0.60.60.80.80.70.80.8-0.8-0.70.9-0.9-0.80.9
Cocaine response before conditioning3.44.14.42.12.12.02.1-2.1-1.92.0-2.0-2.02.0
Saline control response0.10.20.2-0.4-0.4-0.4-0.40.40.5-0.40.40.4-0.4
Bone: connectivity density7.712.114.0-3.6-3.5-3.5-3.53.53.7-3.33.33.6-3.2
Bone: cortical apparent density0.20.30.50.60.70.60.6-0.6-0.60.5-0.5-0.60.4
Bone: cortical area10.115.215.9-3.9-4.0-3.8-3.83.94.0-4.04.03.7-4.0
Bone: cortical porosity0.80.91.20.91.10.90.9-0.9-0.91.0-1.0-0.81.1
Bone: cortical porosity1.31.41.81.11.31.11.1-1.1-1.11.3-1.3-1.01.3
Bone: cortical thickness3.65.96.9-2.4-2.6-2.3-2.42.42.4-2.42.42.2-2.5
Bone: cortical thickness0.20.20.5-0.4-0.4-0.3-0.30.30.4-0.60.60.2-0.7
Bone: cortical tissue density0.30.50.70.70.80.70.7-0.7-0.70.6-0.6-0.60.6
Condit. Reinf. active minus inactive responses0.10.10.40.20.10.20.2-0.2-0.20.5-0.6-0.20.6
Condit. Reinf. active-inactive response ratio0.20.20.3-0.5-0.5-0.5-0.50.50.6-0.20.20.5-0.1
Condit. Reinf. active responses0.70.91.50.80.70.80.8-0.8-0.81.1-1.1-0.81.2
Condit. Reinf. inactive responses2.93.43.61.81.71.81.8-1.8-1.91.9-1.9-1.91.8
Incentive salience index mean0.00.00.1-0.2-0.3-0.1-0.10.10.20.0-0.00.10.0
Condit. Reinf. lever presses0.10.10.3-0.4-0.6-0.4-0.40.40.4-0.30.30.3-0.3
Condit. Reinf. active minus inactive responses0.00.00.10.10.20.10.1-0.1-0.1-0.00.0-0.0-0.1
Condit. Reinf. active-inactive response ratio0.30.30.40.60.60.60.6-0.6-0.50.5-0.5-0.60.5
Condit. Reinf. active responses0.10.20.40.50.60.50.5-0.5-0.50.2-0.2-0.40.2
Condit. Reinf. inactive responses0.50.60.90.81.00.90.9-0.9-0.90.6-0.6-0.80.6
Condit. Reinf. lever presses0.00.00.1-0.00.2-0.00.0-0.0-0.0-0.30.30.0-0.3
Condit. Reinf. lever reinforcers received0.40.61.10.81.00.80.9-0.9-0.80.6-0.6-0.70.5
Conditioned reinforcement - actives1.61.62.01.41.41.31.3-1.3-1.21.2-1.2-1.11.1
Conditioned reinforcement - inactives2.12.32.71.61.51.61.5-1.5-1.51.5-1.5-1.31.5
Conditioned locomotion0.30.40.70.80.80.70.7-0.7-0.60.5-0.5-0.50.4
Patch foraging indifference point 0 sec2.23.63.92.01.81.91.9-1.9-2.01.8-1.8-2.01.7
Patch foraging indifference point AUC0.20.20.30.50.40.50.5-0.5-0.30.3-0.3-0.50.2
Delay disc. indifference point, 0s delay1.21.31.7-1.2-1.3-1.2-1.21.21.3-1.01.01.2-0.9
Delay disc. indifference point, 16s delay1.01.01.1-0.9-1.0-0.9-1.01.01.0-1.01.01.0-1.0
Delay disc. indifference point, 2s delay1.31.51.8-1.3-1.4-1.3-1.31.31.2-1.11.11.2-1.0
Delay disc. indifference point, 24s delay1.51.51.8-1.1-1.2-1.2-1.21.21.2-1.31.31.1-1.3
Delay disc. indifference point, 4s delay0.20.20.4-0.6-0.6-0.5-0.50.50.4-0.40.40.5-0.4
Delay disc. indifference point, 8s delay2.62.73.2-1.6-1.8-1.6-1.61.61.8-1.61.61.6-1.6
Indifference point function ln k3.75.26.0-2.4-2.3-2.4-2.42.42.3-2.22.22.4-2.0
Indifference point function log k3.75.26.0-2.4-2.3-2.4-2.42.42.3-2.22.22.4-2.0
Patch foraging total patch changes 0 sec2.13.43.91.91.81.91.9-1.9-1.91.8-1.8-2.01.7
Patch foraging total patch changes 12 sec2.02.53.11.81.61.71.7-1.7-1.61.4-1.4-1.71.2
Patch foraging total patch changes 18 sec4.05.25.72.42.42.42.4-2.4-2.22.2-2.2-2.32.0
Patch foraging total patch changes 24 sec2.02.52.91.61.61.71.6-1.6-1.61.5-1.5-1.71.3
Patch foraging total patch changes 6 sec2.43.54.02.01.92.02.0-2.0-1.81.8-1.8-1.91.6
Patch foraging time to switch 0 sec2.33.64.31.92.01.91.9-1.9-2.11.9-1.9-1.91.8
Patch foraging water rate 0 sec2.94.75.7-2.2-2.4-2.1-2.22.22.3-2.12.12.1-2.0
Patch foraging water rate 12 sec3.75.76.5-2.5-2.4-2.4-2.42.42.5-2.32.32.6-2.2
Patch foraging water rate 18 sec0.30.40.6-0.6-0.5-0.6-0.60.60.6-0.80.80.5-0.7
Patch foraging water rate 24 sec3.24.44.7-2.2-2.1-2.1-2.12.12.1-2.12.12.1-2.0
Patch foraging water rate 6 sec3.75.35.8-2.4-2.4-2.3-2.32.32.4-2.22.22.4-2.1
Seeking ratio, delayed vs. immediate footshock0.30.30.4-0.6-0.7-0.6-0.60.60.6-0.50.50.6-0.5
Distance traveled before self-admin1.21.21.31.11.11.11.1-1.1-1.11.1-1.1-1.11.1
Distance traveled after self-admin0.20.20.50.40.30.40.4-0.4-0.40.6-0.6-0.30.7
Extensor digitorum longus weight4.216.721.4-3.9-4.0-3.9-4.04.03.8-4.54.53.5-4.6
Bone: elastic displacement4.95.56.72.32.32.22.2-2.2-2.42.5-2.5-2.32.6
Bone: elastic work0.00.00.1-0.00.1-0.1-0.10.1-0.00.2-0.20.10.4
Bone: endosteal estimation8.117.618.5-4.2-4.1-4.2-4.24.24.3-4.24.24.3-4.1
Bone: endosteal perimeter7.315.217.5-3.8-3.7-3.8-3.83.83.9-4.14.13.8-4.2
Epididymis fat weight0.20.40.5-0.7-0.6-0.6-0.60.60.4-0.60.60.6-0.6
Delta time in closed arm before/after self-admin0.20.20.4-0.5-0.5-0.5-0.50.50.6-0.40.40.4-0.4
Delta time in open arm before/after self-admin4.64.55.02.12.02.12.1-2.1-2.12.2-2.2-2.02.2
Diff in mean of infusions in LGA sessions1.51.61.8-1.3-1.3-1.4-1.31.31.3-1.21.21.3-1.1
Delay discount exponential model param0.80.91.21.01.10.91.0-1.0-0.90.9-0.9-0.90.9
Extinction: sum of active levers before priming0.40.40.5-0.6-0.6-0.7-0.70.70.6-0.60.60.6-0.5
Active lever presses in extinction session 60.40.40.6-0.7-0.7-0.7-0.70.70.7-0.60.60.6-0.5
Bone: final force10.316.617.7-4.1-4.2-4.1-4.14.14.2-4.03.94.1-3.8
Bone: final moment10.817.418.5-4.3-4.3-4.3-4.34.34.3-4.04.04.2-3.8
Food consumed during 24 hour testing period1.82.22.8-1.5-1.5-1.5-1.51.51.7-1.41.41.5-1.4
Glucose0.10.20.6-0.2-0.2-0.2-0.20.2-0.0-0.60.60.1-0.8
Heart weight0.00.00.1-0.2-0.1-0.3-0.30.30.2-0.20.20.2-0.1
Delay discount hyperbolic model param0.80.81.11.01.10.90.9-0.9-0.90.8-0.8-0.90.8
Intermittent access intake day 1-15 change1.31.31.91.21.41.31.3-1.3-1.20.9-0.9-1.10.7
Intermittent access intake escalation0.90.91.41.01.21.11.1-1.1-1.00.7-0.7-0.90.5
Intermittent access intake escalation 21.51.52.01.31.41.41.3-1.3-1.21.0-1.0-1.20.8
Intermitt. access day 1 inactive lever presses2.93.13.91.71.81.61.7-1.7-2.01.7-1.7-1.91.8
Intermitt. access day 15 inactive lever presses1.31.41.91.21.21.21.2-1.2-1.41.2-1.2-1.11.2
Intermitt. access escalation Index0.20.20.50.30.50.40.5-0.5-0.60.3-0.2-0.70.2
Intermittent access day 1 total infusions1.21.41.61.31.21.21.2-1.2-1.11.2-1.1-1.21.1
Intermittent access day 15 total infusions2.52.83.81.81.91.81.8-1.8-1.71.4-1.4-1.71.2
Intermittent access terminal intake (last 3 days)2.83.04.01.92.01.91.9-1.9-1.61.5-1.5-1.71.4
Intermittent access total infusions2.52.83.51.81.91.81.8-1.8-1.61.5-1.5-1.71.3
Intermittent access day 1 locomotion0.90.91.31.01.11.01.0-1.0-1.00.8-0.8-1.10.8
Intermittent access day 15 total locomotion1.51.62.71.51.61.41.4-1.4-1.30.9-0.9-1.20.7
Intermittent access total locomotion3.13.65.22.12.32.02.0-2.0-2.01.5-1.5-1.91.4
Intermittent access standard deviation0.50.50.60.80.80.80.8-0.8-0.70.6-0.6-0.80.5
Left kidney weight0.30.91.3-1.0-1.1-1.0-1.01.01.0-0.70.71.1-0.6
Right kidney weight2.77.68.5-2.7-2.8-2.7-2.82.82.7-2.72.72.9-2.7
Cocaine induced anxiety1.21.42.2-1.1-1.0-1.1-1.11.11.1-1.41.41.1-1.5
Post-drug Anxiety5.35.96.4-2.4-2.4-2.4-2.42.42.3-2.52.52.5-2.5
Baseline Anxiety0.91.01.3-1.0-1.2-1.0-1.01.01.0-0.90.91.1-0.8
Tail length0.10.20.40.60.50.60.6-0.6-0.60.3-0.3-0.50.2
Length with tail2.07.27.6-2.7-2.8-2.7-2.72.72.6-2.72.72.7-2.7
Length without tail7.716.917.7-4.2-4.2-4.1-4.14.14.0-4.14.14.1-4.0
Times rat made contact with spout0.10.10.20.30.20.30.3-0.3-0.50.3-0.3-0.40.2
Lifetime Intake2.32.63.41.81.81.81.8-1.8-1.51.4-1.4-1.61.2
Liver weight, left2.13.34.5-1.7-1.6-1.7-1.71.71.7-2.12.11.6-2.1
Liver weight, right1.62.73.5-1.6-1.5-1.6-1.61.61.5-1.81.81.5-1.9
Locomotor activity1.11.72.01.41.41.41.4-1.4-1.21.2-1.2-1.31.2
Locomotor testing distance2.94.85.22.22.32.32.3-2.3-2.12.1-2.1-2.22.1
Locomotor testing rearing2.23.43.91.92.02.02.0-2.0-1.91.6-1.6-1.91.5
Locomotion in novel chamber0.50.70.9-0.8-0.9-0.8-0.80.80.8-0.80.80.8-0.8
Locomotion in novel chamber post-restriction0.00.00.0-0.2-0.2-0.1-0.10.10.1-0.10.10.2-0.0
Fecal boli incidents, locomotor time 12.32.52.81.51.41.51.5-1.5-1.61.7-1.7-1.61.6
Change in fecal boli incidents, locomotor task1.41.31.8-1.2-1.2-1.2-1.21.21.2-0.90.91.4-0.8
Time >=10cm from walls, locomotor time 10.20.20.2-0.4-0.4-0.4-0.40.40.4-0.40.40.4-0.4
Bouts of movement, locomotor time 10.00.00.10.0-0.0-0.1-0.10.10.00.2-0.30.10.4
Total resting periods, locomotor time 10.30.30.80.50.40.40.4-0.4-0.50.7-0.8-0.40.9
Rest time, locomotor task time 10.40.50.70.70.60.60.6-0.6-0.70.8-0.8-0.60.8
Distance moved, locomotor task time 10.10.10.3-0.2-0.0-0.2-0.20.20.1-0.50.50.2-0.5
Vertical activity count, locomotor time 11.51.61.8-1.3-1.2-1.2-1.21.21.3-1.31.31.2-1.3
Time >=10cm from walls, locomotor time 20.70.71.10.80.70.80.8-0.8-0.71.0-1.0-0.71.1
Bouts of movement, locomotor time 22.52.73.0-1.6-1.7-1.7-1.71.71.7-1.61.61.7-1.6
Total resting periods, locomotor time 22.93.13.3-1.7-1.8-1.8-1.81.81.7-1.71.71.8-1.7
Rest time, locomotor task time 20.00.00.1-0.2-0.2-0.1-0.10.1-0.1-0.20.20.1-0.3
Distance moved, locomotor task time 20.10.10.10.30.40.20.3-0.3-0.20.3-0.3-0.20.4
Vertical activity count, locomotor time 20.00.00.1-0.1-0.1-0.1-0.10.10.4-0.20.20.2-0.3
Light reinforcement 12.74.96.32.32.52.32.4-2.4-2.21.9-1.9-2.31.7
Light reinforcement 20.91.21.41.21.21.11.1-1.1-1.01.0-1.0-1.10.9
Bone: marrow area7.917.118.0-4.1-4.0-4.1-4.14.14.2-4.24.24.2-4.1
Bone: maximum diameter4.17.59.1-2.6-2.7-2.6-2.62.62.8-2.92.92.6-3.0
Bone: maximum force14.725.426.2-5.1-5.0-5.1-5.15.15.1-5.05.05.1-4.8
Bone: maximum moment15.226.227.5-5.2-5.1-5.2-5.25.25.2-5.05.05.2-4.8
Mean time between licks in bursts0.10.20.60.20.30.20.3-0.3-0.20.6-0.6-0.10.7
Mean num. licks in bursts0.00.10.3-0.1-0.1-0.2-0.10.10.10.3-0.30.10.5
Cd content in liver0.60.70.80.80.90.90.9-0.9-0.80.7-0.7-0.90.5
Co content in liver0.50.61.10.90.60.90.8-0.8-0.90.5-0.5-1.00.3
Cu content in liver0.60.70.8-0.9-0.8-0.9-0.90.90.5-0.90.90.7-0.8
Fe content in liver0.30.40.70.60.70.70.6-0.6-0.80.3-0.2-0.80.1
K content in liver0.20.20.3-0.5-0.5-0.4-0.50.50.1-0.50.50.4-0.5
Mg content in liver0.00.00.00.1-0.10.10.1-0.1-0.20.2-0.2-0.10.2
Mn content in liver0.10.10.2-0.3-0.3-0.3-0.30.30.10.0-0.00.40.1
Na content in liver0.10.10.20.20.30.20.2-0.2-0.40.1-0.1-0.30.1
Rb content in liver0.30.40.60.70.60.70.7-0.7-0.80.5-0.5-0.80.4
Se content in liver0.60.71.00.80.70.90.9-0.9-1.00.9-0.9-0.80.8
Sr content in liver0.50.40.7-0.6-0.6-0.5-0.50.50.9-0.70.70.5-0.8
Zn content in liver1.82.02.41.51.41.51.5-1.5-1.51.3-1.3-1.61.2
Bone: minimum diameter9.517.819.1-4.2-4.1-4.1-4.24.24.4-4.34.34.2-4.3
Time in familiar zone, hab. session 10.50.40.90.60.50.50.5-0.5-0.60.8-0.8-0.60.9
Time in novel zone, hab. session 10.40.40.7-0.5-0.5-0.5-0.50.50.6-0.80.80.6-0.8
Total zone transitions, hab. session 10.40.50.80.70.70.70.7-0.7-0.60.8-0.8-0.70.9
Total locomotion distance, hab. session 10.00.00.1-0.2-0.1-0.1-0.10.10.20.2-0.20.20.3
Locomotion velocity, hab. session 10.00.00.1-0.2-0.2-0.2-0.20.20.30.0-0.00.30.1
Time in familiar zone, hab. session 20.20.20.4-0.5-0.6-0.6-0.60.60.5-0.30.30.6-0.2
Time in novel zone, hab. session 20.20.20.40.50.60.50.5-0.5-0.50.2-0.2-0.50.1
Total zone transitions, hab. session 20.40.51.00.60.50.60.6-0.6-0.50.9-0.9-0.61.0
Total locomotion distance, hab. session 20.10.20.60.20.20.30.3-0.3-0.20.7-0.7-0.10.8
Locomotion velocity, hab. session 20.10.10.40.00.00.10.2-0.2-0.00.5-0.50.00.6
Novel to familiar place preference ratio2.02.13.3-1.3-1.2-1.4-1.41.41.2-1.71.71.2-1.8
Novelty place preference1.51.62.6-1.1-1.0-1.2-1.21.21.0-1.51.51.0-1.6
Time in novel zone, NPP test1.31.32.3-1.0-0.9-1.0-1.01.00.9-1.41.40.9-1.5
Total zone transitions, NPP test1.52.13.01.41.21.41.4-1.4-1.31.7-1.7-1.41.7
Total locomotion distance, NPP test1.82.53.61.41.41.51.5-1.5-1.31.8-1.8-1.31.9
Locomotion velocity, NPP test1.01.42.31.01.01.11.1-1.1-1.01.4-1.4-1.01.5
Intraocular pressure7.710.811.23.33.33.33.3-3.3-3.23.3-3.3-3.23.3
Delta distance traveled before/after self-admin0.10.10.2-0.3-0.3-0.3-0.30.30.2-0.20.20.4-0.1
Delta ambulatory time before/after self-admin0.00.00.0-0.1-0.1-0.0-0.10.10.0-0.10.10.2-0.1
Parametrial fat weight2.34.44.62.12.02.12.1-2.1-2.22.1-2.1-2.12.1
Pavlov. Cond. lever latency0.10.10.2-0.2-0.1-0.4-0.30.30.3-0.20.10.30.0
Pavlov. Cond. magazine entry latency0.00.00.0-0.00.0-0.0-0.00.0-0.0-0.10.10.1-0.1
Pavlov. Cond. change in total contacts0.00.10.2-0.2-0.2-0.0-0.10.10.1-0.30.30.1-0.5
Pavlov. Cond. index score0.00.10.3-0.2-0.2-0.0-0.10.10.0-0.40.40.0-0.5
Pavlov. Cond. latency score0.00.00.2-0.1-0.20.10.0-0.0-0.0-0.30.3-0.0-0.4
Pavlov. Cond. lever contacts0.40.50.70.70.60.80.8-0.8-0.80.5-0.4-0.90.3
Pavlov. Cond. magazine entry number0.00.00.1-0.1-0.2-0.2-0.20.20.20.0-0.00.20.1
Pavlov. Cond. intertrial magazine entries0.50.61.60.60.50.60.6-0.6-0.51.1-1.1-0.61.3
Pavlov. Cond. lever-magazine prob. diff.0.20.30.6-0.4-0.5-0.3-0.40.40.4-0.60.60.3-0.8
Pavlov. Cond. response bias0.10.10.10.30.30.30.3-0.3-0.30.1-0.1-0.30.0
Pavlov. Cond. lever latency0.00.00.1-0.1-0.1-0.1-0.10.10.20.0-0.00.20.1
Pavlov. Cond. magazine entry latency1.21.31.5-1.1-1.1-1.2-1.21.21.2-1.21.21.1-1.2
Pavlov. Cond. change in total contacts1.62.13.3-1.4-1.5-1.3-1.41.41.1-1.71.71.2-1.8
Pavlov. Cond. index score0.50.71.1-0.8-0.8-0.8-0.80.80.7-1.01.00.7-1.0
Pavlov. Cond. latency score0.60.71.0-0.8-0.8-0.8-0.80.80.7-0.90.90.7-1.0
Pavlov. Cond. lever contacts0.10.10.30.40.40.40.4-0.4-0.50.2-0.2-0.50.1
Pavlov. Cond. magazine entry number2.42.93.51.71.61.71.7-1.7-1.61.8-1.8-1.61.9
Pavlov. Cond. intertrial magazine entries5.47.17.92.62.52.72.6-2.6-2.52.8-2.8-2.62.8
Pavlov. Cond. lever-magazine prob. diff.1.01.31.7-1.1-1.1-1.1-1.11.10.9-1.31.30.9-1.3
Pavlov. Cond. response bias0.00.00.10.10.10.10.1-0.1-0.2-0.20.2-0.2-0.3
Time in closed arm before self-admin1.71.92.5-1.3-1.2-1.3-1.31.31.3-1.61.61.3-1.6
Time in closed arm after self-admin0.80.81.0-0.8-0.7-0.9-0.90.90.9-1.01.00.9-1.0
Time in open arm before self-admin0.70.81.1-0.9-0.8-0.9-0.90.90.8-1.01.00.8-1.0
Time in open arm after self-admin0.30.40.60.60.50.50.5-0.5-0.70.7-0.7-0.60.8
Bone: periosteal estimation12.525.827.0-5.1-5.0-5.0-5.05.05.2-5.25.25.0-5.2
Bone: periosteal perimeter10.817.918.8-4.2-4.2-4.2-4.24.24.3-4.34.34.1-4.3
Bone: post-yield work8.812.012.7-3.5-3.3-3.5-3.53.53.6-3.53.53.5-3.4
Progressive ratio test 1 active lever presses4.54.75.72.32.42.32.3-2.3-2.02.0-2.0-2.21.8
Progressive ratio test 1 breakpoint4.04.25.32.22.32.22.2-2.2-1.91.9-1.8-2.11.7
Progressive ratio test 1 inactive lever presses3.74.04.62.12.12.02.0-2.0-2.11.8-1.8-2.01.8
Progressive ratio test 2 active lever presses2.32.43.21.71.81.71.7-1.7-1.71.3-1.3-1.51.1
Progressive ratio test 2 breakpoint2.93.34.22.02.02.01.9-1.9-1.91.6-1.6-1.71.4
Progressive ratio test 2 inactive lever presses2.52.93.81.92.01.81.8-1.8-1.91.5-1.5-1.51.4
Incentive Sensitization - Responses0.00.00.2-0.0-0.0-0.0-0.00.0-0.0-0.20.20.5-0.3
Incentive Sensitization - Breakpoint0.00.00.10.10.10.10.1-0.1-0.1-0.10.10.4-0.2
Sum of active levers in priming session hrs 5-60.00.00.10.20.30.10.1-0.1-0.20.1-0.1-0.20.2
Progressive ratio0.00.00.10.20.20.20.2-0.2-0.10.1-0.1-0.10.0
Food seeking constrained by brief footshock0.30.40.50.70.70.70.6-0.6-0.60.5-0.5-0.70.5
Seeking ratio, punishment vs. effort0.00.00.00.10.10.00.1-0.1-0.20.1-0.1-0.20.1
Retroperitoneal fat weight0.51.52.01.21.21.31.3-1.3-1.31.1-1.1-1.41.0
Reaction time number correct1.42.02.9-1.6-1.4-1.6-1.51.51.6-1.11.11.7-0.9
Reaction time mean minus median8.411.111.63.43.43.43.4-3.4-3.43.3-3.3-3.33.2
Reaction time mean minus median AUC6.17.98.82.92.92.82.8-2.8-3.02.7-2.7-2.72.7
Reaction time num false alarms1.62.22.41.51.41.51.5-1.5-1.41.6-1.6-1.51.5
Reaction time num false alarms AUC2.33.23.41.81.81.81.8-1.8-1.81.8-1.8-1.81.8
Reaction time trials correct on left1.42.02.9-1.6-1.4-1.6-1.51.51.6-1.11.11.7-0.9
Reaction time trials on left1.11.52.3-1.4-1.2-1.4-1.31.31.4-0.90.91.5-0.7
Reaction time mean0.60.91.21.00.91.01.0-1.0-1.10.9-0.9-0.90.8
Reaction time mean AUC0.40.50.70.70.70.70.7-0.7-0.90.7-0.6-0.70.6
Median of all reaction times0.00.00.1-0.1-0.1-0.1-0.10.10.0-0.20.20.1-0.3
Reaction time omissions10.213.914.63.83.83.73.7-3.7-3.63.8-3.8-3.63.7
Reaction time false alarm rate2.63.74.12.01.92.02.0-2.0-2.01.8-1.8-2.01.7
Reaction time premature initiation rate6.18.29.43.13.03.13.0-3.0-2.92.5-2.5-3.02.3
Reaction time premature initiations2.84.04.72.12.22.12.1-2.1-1.91.8-1.8-2.01.7
Std. dev. reaction times6.28.79.33.03.03.03.0-3.0-3.02.9-2.9-2.92.8
Reaction time trials completed1.11.52.3-1.4-1.2-1.4-1.31.31.4-0.90.91.5-0.7
Reaction time trials AUC1.72.53.6-1.7-1.6-1.7-1.71.71.8-1.21.21.9-1.0
Run reversals in cocaine runway, females0.00.00.00.10.10.00.0-0.0-0.1-0.20.2-0.1-0.2
Run reversals in cocaine runway, males1.61.51.61.21.21.21.2-1.2-1.11.3-1.3-1.21.3
Latency to leave start box in cocaine runway0.00.00.00.10.00.10.1-0.1-0.10.1-0.1-0.1-0.0
Latency to leave start box in cocaine runway, F1.71.92.01.41.41.41.4-1.4-1.31.3-1.3-1.31.2
Latency to leave start box in cocaine runway, M2.12.02.2-1.4-1.5-1.4-1.41.41.4-1.41.41.4-1.4
Std. dev. time between licks in bursts0.91.11.41.11.11.21.2-1.2-1.01.0-1.0-1.10.8
Total sessions with >9 infusions0.80.91.31.11.11.11.1-1.1-0.70.8-0.8-0.90.5
Short access day 1 total inactive lever presses1.41.51.81.31.41.41.3-1.3-1.41.0-1.0-1.30.8
Short access day 10 total inactive lever presses0.20.30.60.50.50.40.4-0.4-0.80.4-0.4-0.60.5
Short access day 1 total infusions0.00.00.10.30.30.30.3-0.3-0.10.1-0.1-0.2-0.0
Short access day 10 total infusions0.91.01.31.11.11.11.1-1.1-0.90.8-0.8-1.10.7
Short access total infusions0.40.50.80.80.90.90.8-0.8-0.50.5-0.4-0.70.2
Short access day 1 locomotion0.10.10.20.40.50.40.4-0.4-0.30.1-0.1-0.4-0.1
Short access day 10 total locomotion0.20.20.30.50.50.40.4-0.4-0.50.3-0.3-0.50.3
Short access total locomotion0.40.40.80.80.90.70.7-0.7-0.70.4-0.4-0.80.3
One hour access (0.3 mA shock)0.20.30.50.60.70.70.6-0.6-0.40.2-0.2-0.60.1
Compulsive drug intake0.90.91.7-1.1-1.3-1.1-1.11.10.9-0.60.60.8-0.5
One hour access (shock baseline)0.20.20.50.60.70.60.5-0.5-0.3-0.00.0-0.2-0.2
Social response proportion0.10.10.20.40.30.40.4-0.4-0.40.3-0.3-0.30.2
Social responses7.59.610.73.23.33.33.2-3.2-3.22.8-2.8-3.22.6
Social time0.00.00.00.10.10.00.0-0.0-0.00.1-0.1-0.10.2
Soleus weight0.61.92.3-1.3-1.3-1.3-1.31.31.3-1.51.51.3-1.5
Bone: stiffness17.728.028.7-5.3-5.2-5.3-5.35.35.3-5.35.35.4-5.2
Tibialis anterior weight1.13.98.3-1.6-1.7-1.6-1.71.71.3-2.62.61.3-2.9
Time to tail flick, vehicle, before self-admin1.11.11.61.01.00.91.0-1.0-1.01.2-1.2-1.01.3
Time to tail flick, vehicle, after self-admin0.30.30.4-0.5-0.4-0.5-0.50.50.6-0.60.60.5-0.6
Time to tail flick, test, before self-admin0.50.50.90.70.60.50.5-0.5-0.60.8-0.9-0.51.0
Time to tail flick, test, after self-admin0.20.20.3-0.4-0.4-0.5-0.40.40.5-0.50.50.5-0.5
Delta time to tail flick, vehicle, before/after SA0.50.50.7-0.7-0.6-0.6-0.60.60.7-0.80.80.7-0.9
Delta time to tail flick, test, before/after SA0.30.20.5-0.4-0.4-0.4-0.40.40.5-0.60.60.4-0.7
Tibia length7.822.024.1-4.7-4.8-4.5-4.64.64.5-4.84.84.6-4.9
Ambulatory time before self-admin4.14.34.42.12.12.02.0-2.0-2.12.1-2.1-2.12.1
Ambulatory time after self-admin1.92.02.11.41.41.51.4-1.4-1.41.5-1.5-1.41.4
Bone: tissue strength1.11.01.3-1.1-1.0-1.1-1.11.11.1-0.90.91.1-0.7
Total heroin consumption2.12.43.1-1.4-1.4-1.5-1.51.51.5-1.71.71.4-1.8
Bone: trabecular number6.610.311.6-3.4-3.3-3.3-3.33.23.4-3.03.03.4-2.8
Bone: trabecular spacing2.43.13.51.91.81.81.8-1.8-1.81.6-1.6-1.91.6
Bone: trabecular thickness0.10.10.10.30.30.40.4-0.4-0.20.3-0.3-0.30.3
Bone: trabecular tissue density0.10.10.10.30.40.30.3-0.3-0.10.3-0.3-0.20.2
Water consumed over 24 hours0.00.00.1-0.1-0.1-0.1-0.10.10.3-0.10.00.2-0.0
Number of responses in last shaping day0.10.10.6-0.10.1-0.1-0.10.10.1-0.60.60.1-0.8