Hub : Genes

Sptbn5

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 BLA mRNA stability Sptbn5 0.11 0.06 2.3e-04 0.03 0 0 0.01 7.7e-03 1.9e-01 2.8e-01 1.1e-01
2 PL intron excision ratio chr3_107017537_107018049 0.07 0.04 1.1e-08 0.06 0.07 0.07 0.07 2.3e-07 1.5e-08 1.5e-08 2.1e-08
3 Brain isoform ratio XM_039106497.1 0.03 0.02 2.5e-03 0.04 0.02 0.02 0.03 1.6e-04 5.6e-03 6.2e-03 5.3e-04
4 Brain mRNA stability Sptbn5 0.16 0.07 1.4e-11 0.1 0.13 0.13 0.13 7.2e-10 4.4e-12 3.0e-12 4.7e-12
5 PL mRNA stability Sptbn5 0.11 0.05 1.3e-09 0.07 0.08 0.07 0.08 8.7e-08 2.7e-09 1.1e-08 5.4e-09
6 PL intron excision ratio chr3_107014161_107016922 0.04 0.02 1.6e-05 0.04 0.05 0.04 0.04 3.0e-05 6.5e-06 3.4e-05 2.3e-05
7 NAcc intron excision ratio chr3_107017537_107018049 0.05 0.03 1.1e-05 0.03 0.04 0.04 0.03 6.8e-05 1.2e-05 2.6e-05 6.5e-05
8 Brain gene expression Sptbn5 0.26 0.1 0.0e+00 0.21 0.21 0.2 0.21 2.5e-19 1.7e-19 6.1e-18 4.9e-19
9 Eye gene expression Sptbn5 0.35 0.17 6.3e-03 0.04 0.03 0.06 0.05 7.9e-02 1.0e-01 4.3e-02 6.8e-02
10 PL isoform ratio XM_039106497.1 0.04 0.02 2.5e-05 0.04 0.03 0.02 0.02 5.1e-05 4.1e-04 3.3e-03 1.0e-03
11 PL intron excision ratio chr3_107017188_107017466 0.02 0.01 2.3e-03 0.01 0.01 0.01 0.01 1.0e-02 1.6e-02 2.9e-02 3.0e-02
12 IL gene expression Sptbn5 0.4 0.16 1.4e-06 0.18 0.17 0.16 0.15 3.6e-05 6.7e-05 1.2e-04 1.8e-04
13 OFC gene expression Sptbn5 0.26 0.13 2.1e-04 0.12 0.11 0.08 0.1 8.9e-04 1.4e-03 6.4e-03 2.4e-03
14 PL gene expression Sptbn5 0.26 0.09 0.0e+00 0.27 0.3 0.31 0.3 3.5e-29 5.3e-34 4.5e-35 5.9e-33
15 NAcc mRNA stability Sptbn5 0.04 0.03 6.8e-03 0.01 0 0.01 0 1.4e-02 1.2e-01 3.2e-02 1.9e-01
16 Brain intron excision ratio chr3_107017004_107017087 0.04 0.03 4.9e-03 0.02 0.01 0.01 0.01 9.2e-03 7.5e-02 2.1e-02 5.3e-02
17 Adipose mRNA stability Sptbn5 0.1 0.06 1.8e-04 0.03 0.02 0.02 0.03 1.4e-04 1.7e-03 9.7e-04 8.2e-04
18 Liver gene expression Sptbn5 0.14 0.06 7.8e-16 0.14 0.14 0.14 0.14 2.2e-15 4.1e-15 4.1e-15 4.7e-15
19 BLA gene expression Sptbn5 0.2 0.09 3.5e-09 0.14 0.12 0.11 0.13 5.7e-08 4.4e-07 1.2e-06 1.2e-07
20 Liver mRNA stability Sptbn5 0.03 0.02 1.8e-03 0.03 0.02 0.02 0.02 4.8e-04 2.2e-03 6.4e-03 2.7e-03
21 Liver intron excision ratio chr3_107018153_107018261 0.04 0.03 4.0e-04 0.01 0.02 0.01 0.01 3.0e-02 2.4e-03 2.6e-02 2.9e-02

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21
Bone: apparent density0.61.11.9-1.0-1.1-1.0-0.60.6-1.41.00.71.2-1.2-1.2-1.2-1.2-1.1-1.2-1.11.2-0.4-1.3-0.50.4
Area under the delay curve1.81.97.3-0.5-0.6-0.50.9-0.1-0.70.80.61.7-1.8-1.8-1.7-1.7-1.70.2-0.3-0.2-2.7-1.6-2.02.5
BMI with tail3.912.719.4-4.1-4.2-4.0-3.03.4-4.44.13.74.0-3.9-3.9-3.9-3.9-3.8-3.1-4.23.1-0.2-4.1-0.01.1
BMI without tail4.08.212.2-3.1-3.2-3.1-2.12.0-3.52.82.43.3-3.2-3.2-3.4-3.4-3.0-3.4-3.03.3-0.6-3.2-1.10.9
Body weight4.619.328.3-5.1-5.3-5.0-4.14.4-5.35.04.74.8-4.7-4.7-4.6-4.6-4.7-3.9-5.24.00.3-4.8-0.01.0
Weight adjusted by age0.91.01.7-1.1-1.0-1.1-0.71.1-0.81.21.31.3-1.3-1.3-1.1-1.1-1.3-0.2-0.70.2-0.4-0.9-0.50.9
Bone surface0.71.22.4-1.3-1.4-1.3-1.21.0-1.51.11.01.0-0.9-0.9-0.9-0.9-0.8-1.4-1.41.40.5-1.10.6-0.4
Bone volume0.81.32.4-1.3-1.3-1.3-1.21.0-1.61.21.21.1-1.1-1.1-1.1-1.1-0.8-1.5-1.21.50.3-1.00.7-0.3
Breakpoint value in progressive ratio session0.10.20.6-0.0-0.1-0.1-0.2-0.1-0.4-0.1-0.1-0.10.20.20.40.40.4-0.8-0.30.60.3-0.10.8-0.8
Number of licking bursts0.30.41.00.70.70.70.6-0.90.2-0.8-0.8-0.60.60.60.60.61.0-0.40.60.4-0.10.50.6-0.7
Context. condit. distance diff. score2.12.67.3-2.0-1.8-2.0-2.11.5-1.91.31.51.3-1.3-1.3-1.2-1.2-1.0-2.7-1.32.71.2-0.60.5-1.0
Locomotion velocity, session 13.43.76.42.52.32.32.5-2.22.4-2.0-2.1-1.61.41.41.41.41.22.52.2-2.4-1.31.3-1.41.0
Locomotion distance, session 11.41.93.21.71.71.61.8-1.71.8-1.5-1.6-1.10.90.90.90.90.81.51.7-1.4-1.11.0-1.50.8
Locomotion velocity, session 21.21.45.1-0.1-0.2-0.11.0-0.5-0.30.40.11.3-1.5-1.5-1.5-1.5-1.30.00.1-0.0-2.3-1.2-2.32.1
Locomotion distance, session 20.50.71.51.01.01.01.1-1.20.9-1.1-1.2-0.70.50.50.50.50.50.31.0-0.3-0.60.6-1.10.2
Locomotion velocity, session 30.40.52.70.60.60.51.2-0.80.3-0.3-0.20.4-0.5-0.5-0.6-0.6-0.10.61.0-0.5-1.6-0.1-0.81.1
Locomotion distance, session 30.40.42.10.30.60.30.3-0.80.3-0.7-0.1-0.10.10.10.10.11.0-0.91.40.9-0.21.30.6-0.8
Stereotopy head waving bouts, day 32.83.25.6-1.8-1.8-1.8-1.01.6-1.62.12.02.3-2.3-2.3-2.2-2.2-2.4-0.5-1.50.5-1.0-2.1-0.91.6
Stereotopy head waving duration, day 33.84.68.9-1.8-1.9-1.7-0.51.4-1.92.31.92.7-2.8-2.8-2.7-2.7-2.9-0.3-1.90.4-1.8-3.0-1.72.6
Locomotion velocity, session 70.30.31.2-0.6-0.2-0.6-0.40.1-0.20.10.60.7-0.6-0.6-0.7-0.7-0.2-1.10.71.1-0.20.6-0.4-0.1
Locomotion distance, session 70.30.41.7-0.3-0.0-0.3-0.7-0.0-0.0-0.3-0.1-0.30.40.40.40.40.6-1.20.41.21.11.00.5-1.3
Stereotopy head waving bouts, day 70.10.10.4-0.3-0.3-0.3-0.40.7-0.20.50.60.2-0.2-0.2-0.2-0.2-0.20.4-0.4-0.40.3-0.30.50.1
Stereotopy head waving duration, day 70.10.10.8-0.00.00.0-0.00.40.10.30.50.00.10.10.00.00.10.9-0.0-0.90.0-0.00.70.2
Locomotion velocity, session 82.02.45.1-1.3-1.2-1.4-0.40.6-1.31.31.22.1-2.3-2.3-2.2-2.2-1.9-1.3-0.51.3-1.4-1.4-1.81.5
Locomotion distance, session 80.60.94.2-1.0-0.9-1.1-1.00.4-0.90.40.60.7-0.8-0.8-0.7-0.7-0.6-2.0-0.32.10.5-0.0-0.5-0.6
Degree of sensitization distance0.50.52.7-0.2-0.3-0.2-1.00.70.00.1-0.0-0.70.80.80.90.90.20.1-0.8-0.21.60.20.8-1.0
Degree of sensitization stereotypy0.40.41.50.20.40.2-0.20.20.5-0.30.1-0.70.80.80.70.70.80.50.4-0.50.90.91.2-0.9
Conditioned locomotion2.22.53.8-1.9-1.9-1.9-1.51.4-1.91.61.51.8-1.7-1.7-1.7-1.7-1.6-1.9-1.62.00.1-1.5-0.30.2
Cocaine response after cond. corrected1.51.74.21.71.71.71.9-2.11.0-1.7-1.7-1.11.01.01.01.01.60.41.6-0.3-1.00.90.0-0.2
Cocaine response after cond. not corrected2.12.45.92.12.02.12.3-2.41.3-2.0-2.1-1.21.11.11.11.11.50.71.8-0.7-1.40.9-0.60.2
Cocaine response before conditioning0.20.31.50.40.30.40.5-0.30.6-0.2-0.4-0.0-0.0-0.0-0.0-0.0-0.30.80.3-0.9-0.6-0.0-1.20.9
Saline control response2.43.16.1-2.2-2.3-2.2-2.12.5-1.72.32.31.7-1.6-1.6-1.6-1.6-2.0-0.7-2.20.70.7-1.60.20.5
Bone: connectivity density0.40.61.6-0.8-1.0-0.8-0.70.9-0.90.90.60.7-0.7-0.7-0.7-0.7-0.9-0.2-1.30.30.1-1.2-0.20.4
Bone: cortical apparent density1.41.84.90.80.80.7-0.2-0.30.8-1.0-0.6-1.61.81.81.81.81.90.30.5-0.31.71.62.2-2.0
Bone: cortical area1.62.33.3-1.8-1.7-1.8-1.31.5-1.81.71.81.8-1.8-1.8-1.8-1.8-1.6-1.3-1.41.3-0.2-1.50.10.5
Bone: cortical porosity1.51.65.31.41.41.42.1-2.01.1-1.2-1.5-0.2-0.1-0.10.10.10.10.51.6-0.5-2.10.2-2.31.5
Bone: cortical porosity0.80.94.20.50.50.51.3-1.10.3-0.3-0.50.6-0.8-0.8-0.7-0.7-0.60.20.8-0.2-1.9-0.4-2.01.6
Bone: cortical thickness1.11.83.0-1.4-1.4-1.4-0.81.0-1.41.41.41.7-1.7-1.7-1.7-1.7-1.5-1.0-1.01.0-0.6-1.4-0.50.8
Bone: cortical thickness0.20.20.80.30.20.30.3-0.6-0.4-0.4-0.4-0.20.20.20.30.30.6-0.9-0.10.9-0.1-0.10.8-0.6
Bone: cortical tissue density1.31.74.60.80.80.8-0.2-0.30.8-1.0-0.7-1.61.81.81.81.81.80.30.5-0.31.61.52.2-1.9
Condit. Reinf. active minus inactive responses0.91.03.6-0.00.1-0.1-1.00.90.6-0.00.4-1.11.21.21.21.20.90.9-0.0-0.91.91.21.8-1.3
Condit. Reinf. active-inactive response ratio0.50.51.7-0.9-0.8-0.9-1.21.3-0.50.91.20.3-0.2-0.2-0.2-0.2-0.30.0-0.60.01.0-0.01.2-0.5
Condit. Reinf. active responses1.92.47.00.40.50.3-1.10.81.2-0.5-0.1-1.92.12.12.02.01.61.30.3-1.32.62.02.2-2.0
Condit. Reinf. inactive responses1.92.34.50.90.90.8-0.4-0.11.4-1.1-0.8-2.02.12.12.12.11.80.80.9-0.82.12.11.6-1.9
Incentive salience index mean1.51.83.60.70.70.6-0.50.41.3-0.6-0.3-1.71.81.81.81.81.31.70.5-1.61.91.61.5-1.3
Condit. Reinf. lever presses1.01.43.50.90.70.7-0.20.21.4-0.6-0.5-1.61.61.61.51.51.01.90.4-1.81.31.20.7-0.7
Condit. Reinf. active minus inactive responses1.61.95.5-1.6-1.7-1.6-2.32.0-1.41.41.30.3-0.1-0.1-0.1-0.1-0.5-1.0-2.11.02.2-0.61.7-1.4
Condit. Reinf. active-inactive response ratio1.11.23.4-1.2-1.3-1.2-1.81.5-1.11.01.00.2-0.0-0.00.00.0-0.3-0.9-1.60.91.8-0.41.4-1.3
Condit. Reinf. active responses2.02.87.8-2.0-2.1-2.0-2.82.6-1.71.81.80.6-0.4-0.4-0.3-0.3-0.8-1.1-2.41.12.5-0.72.0-1.5
Condit. Reinf. inactive responses1.21.44.1-1.5-1.5-1.5-1.92.0-1.11.51.60.6-0.5-0.5-0.5-0.5-0.8-0.2-1.60.21.4-0.71.4-0.6
Condit. Reinf. lever presses0.91.23.8-1.2-1.3-1.2-1.62.0-0.91.51.50.5-0.4-0.4-0.4-0.4-0.80.5-1.6-0.51.2-0.81.3-0.2
Condit. Reinf. lever reinforcers received1.82.57.3-1.9-2.0-1.9-2.72.5-1.51.71.70.4-0.2-0.2-0.2-0.2-0.7-0.7-2.30.72.5-0.71.9-1.4
Conditioned reinforcement - actives0.20.20.8-0.1-0.10.10.10.30.20.30.10.1-0.2-0.2-0.2-0.2-0.60.8-0.2-0.8-0.2-0.3-0.90.8
Conditioned reinforcement - inactives0.20.21.0-0.4-0.3-0.2-0.50.2-0.30.00.2-0.0-0.1-0.10.20.20.1-1.0-0.11.00.70.30.2-0.8
Conditioned locomotion0.50.62.70.10.10.20.50.30.70.40.20.3-0.4-0.4-0.4-0.4-0.91.70.1-1.7-0.9-0.3-1.21.6
Patch foraging indifference point 0 sec2.13.46.1-1.6-1.7-1.6-0.92.2-1.22.42.42.0-2.3-2.3-2.4-2.4-2.51.0-1.5-0.8-0.9-2.0-0.82.1
Patch foraging indifference point AUC2.32.74.71.81.71.50.9-1.21.9-1.7-1.4-1.92.22.21.91.92.01.41.6-1.40.71.91.0-1.0
Delay disc. indifference point, 0s delay0.60.73.00.30.30.30.9-0.10.60.20.20.3-0.2-0.2-0.4-0.4-0.51.70.4-1.7-1.4-0.3-0.91.7
Delay disc. indifference point, 16s delay1.01.16.80.50.50.51.6-1.00.3-0.2-0.30.7-0.8-0.8-0.7-0.7-0.50.80.7-0.7-2.6-0.5-1.42.0
Delay disc. indifference point, 2s delay0.50.51.1-1.0-0.8-1.0-1.01.0-0.80.91.00.8-0.7-0.7-0.6-0.6-0.6-0.6-0.60.60.5-0.30.1-0.1
Delay disc. indifference point, 24s delay1.31.32.61.41.31.31.6-1.31.4-1.1-1.1-0.80.60.60.70.70.51.61.2-1.5-1.30.6-1.01.0
Delay disc. indifference point, 4s delay1.01.13.9-0.3-0.3-0.30.7-0.2-0.30.50.21.1-1.2-1.2-1.2-1.2-1.30.2-0.1-0.2-2.0-1.1-1.91.9
Delay disc. indifference point, 8s delay3.53.79.3-1.2-1.2-1.20.50.4-1.41.61.42.5-2.6-2.6-2.4-2.4-2.4-0.1-1.00.1-3.0-2.4-1.83.0
Indifference point function ln k3.24.56.9-2.4-2.3-2.2-1.41.4-2.62.11.92.5-2.6-2.6-2.4-2.4-2.2-2.6-2.02.6-0.6-2.2-0.70.7
Indifference point function log k3.24.56.9-2.4-2.3-2.2-1.41.4-2.62.11.92.5-2.6-2.6-2.4-2.4-2.2-2.6-2.02.6-0.6-2.2-0.70.7
Patch foraging total patch changes 0 sec1.82.95.4-1.5-1.6-1.4-0.92.1-1.12.32.31.8-2.0-2.0-2.1-2.1-2.21.0-1.4-0.8-0.7-1.8-0.51.9
Patch foraging total patch changes 12 sec0.30.42.2-0.0-0.1-0.3-0.61.00.50.50.8-0.10.30.30.00.0-0.11.5-0.1-1.30.70.30.50.1
Patch foraging total patch changes 18 sec0.40.61.80.70.60.50.10.01.0-0.4-0.1-0.81.01.00.60.60.71.30.6-1.30.51.00.5-0.3
Patch foraging total patch changes 24 sec1.21.43.7-0.7-1.2-1.0-0.51.2-0.91.51.11.2-1.2-1.2-1.5-1.5-1.60.6-1.7-0.4-0.6-1.9-0.61.4
Patch foraging total patch changes 6 sec0.20.21.70.20.20.1-0.20.60.50.20.6-0.20.10.10.20.20.11.30.4-1.20.30.60.50.2
Patch foraging time to switch 0 sec0.30.52.00.40.30.4-0.20.40.7-0.1-0.1-0.80.80.81.01.00.41.40.0-1.40.90.60.7-0.3
Patch foraging water rate 0 sec0.71.23.0-1.3-1.2-1.3-1.21.0-1.41.01.21.0-0.9-0.9-1.0-1.0-0.5-1.7-0.91.70.5-0.60.8-0.6
Patch foraging water rate 12 sec0.40.63.8-0.2-0.1-0.1-0.2-0.5-0.8-0.4-0.3-0.10.10.10.20.20.7-2.0-0.01.80.50.20.9-1.4
Patch foraging water rate 18 sec0.50.72.1-0.5-0.4-0.40.2-0.3-1.00.30.20.9-1.1-1.1-1.1-1.1-0.5-1.4-0.11.4-1.0-0.7-0.40.3
Patch foraging water rate 24 sec0.91.34.9-1.1-0.8-1.1-1.40.8-1.20.51.00.2-0.2-0.2-0.1-0.10.5-2.0-0.51.91.40.32.2-1.9
Patch foraging water rate 6 sec0.91.44.60.50.70.6-0.1-0.80.2-1.1-0.8-1.31.31.31.31.31.8-1.10.71.11.31.31.7-2.2
Seeking ratio, delayed vs. immediate footshock1.11.34.0-1.2-1.1-1.2-1.91.3-1.20.80.80.3-0.0-0.00.10.1-0.1-1.6-1.01.72.0-0.11.3-1.6
Distance traveled before self-admin0.20.20.6-0.5-0.6-0.4-0.40.5-0.50.50.30.5-0.2-0.2-0.4-0.4-0.5-0.2-0.70.10.0-0.8-0.10.2
Distance traveled after self-admin0.30.31.5-0.2-0.4-0.2-0.70.3-0.50.10.1-0.20.30.30.40.40.3-0.7-0.70.81.0-0.21.2-1.1
Extensor digitorum longus weight0.20.81.6-0.8-0.7-0.9-0.30.4-0.90.80.91.3-1.2-1.2-1.3-1.3-0.8-0.8-0.20.8-0.8-0.8-0.30.6
Bone: elastic displacement0.10.20.50.30.30.30.5-0.20.4-0.10.10.1-0.2-0.2-0.1-0.1-0.10.70.6-0.7-0.70.1-0.40.7
Bone: elastic work0.50.71.8-0.9-0.9-1.0-0.81.1-0.71.11.41.0-0.9-0.9-0.9-0.9-0.80.1-0.6-0.1-0.0-0.60.40.4
Bone: endosteal estimation0.10.20.9-0.3-0.2-0.3-0.40.1-0.50.00.10.10.00.0-0.0-0.00.2-0.9-0.30.90.4-0.00.5-0.7
Bone: endosteal perimeter0.00.00.1-0.1-0.0-0.0-0.10.0-0.1-0.10.0-0.10.10.10.10.10.2-0.3-0.00.30.20.10.3-0.4
Epididymis fat weight0.61.32.3-1.5-1.4-1.5-1.21.3-1.21.41.51.4-1.2-1.2-1.3-1.3-1.2-0.8-1.00.80.0-1.0-0.20.4
Delta time in closed arm before/after self-admin0.30.21.0-0.4-0.1-0.3-0.70.30.1-0.10.2-0.20.40.40.40.40.3-0.60.30.61.00.80.3-0.9
Delta time in open arm before/after self-admin1.61.66.1-1.4-1.3-1.4-1.50.8-1.70.80.81.0-0.8-0.8-0.8-0.8-0.5-2.5-1.22.40.8-0.70.9-1.1
Diff in mean of infusions in LGA sessions0.20.31.4-0.3-0.2-0.4-0.90.6-0.00.20.3-0.30.40.40.50.50.3-0.1-0.2-0.11.20.40.8-0.9
Delay discount exponential model param1.31.45.90.30.30.3-0.90.30.5-0.6-0.3-1.41.41.41.31.31.3-0.20.20.22.41.31.8-2.2
Extinction: sum of active levers before priming0.90.91.71.11.21.21.3-1.11.0-1.0-0.9-0.80.70.70.90.90.71.11.1-1.1-0.80.6-0.40.3
Active lever presses in extinction session 60.30.31.60.30.30.40.8-0.60.2-0.2-0.40.3-0.4-0.4-0.2-0.2-0.30.20.3-0.2-1.3-0.4-1.11.0
Bone: final force1.01.63.4-1.6-1.4-1.7-1.81.5-1.31.21.60.9-0.8-0.8-0.8-0.8-0.5-1.7-0.81.71.2-0.01.2-1.0
Bone: final moment0.71.22.6-1.5-1.2-1.5-1.61.3-1.11.01.50.8-0.7-0.7-0.7-0.7-0.4-1.5-0.61.51.00.01.2-1.0
Food consumed during 24 hour testing period0.10.20.50.40.30.40.3-0.70.0-0.6-0.7-0.30.30.30.30.30.4-0.60.10.6-0.00.1-0.1-0.4
Glucose0.61.03.2-1.3-1.0-1.2-1.10.7-1.10.71.01.0-0.9-0.9-0.9-0.9-0.5-1.8-0.41.70.4-0.10.4-0.6
Heart weight5.78.112.6-3.4-3.5-3.5-3.23.1-3.43.22.93.0-2.7-2.7-2.9-2.9-2.9-2.7-3.52.80.9-2.8-0.10.2
Delay discount hyperbolic model param1.41.54.90.50.50.5-0.60.00.6-0.8-0.5-1.51.61.61.41.41.5-0.10.30.02.21.41.8-2.1
Intermittent access intake day 1-15 change0.30.32.6-0.1-0.1-0.00.1-0.6-0.6-0.3-0.30.1-0.2-0.2-0.2-0.20.3-1.60.11.6-0.10.10.3-0.7
Intermittent access intake escalation0.50.53.0-0.00.10.1-0.0-0.6-0.4-0.5-0.5-0.20.20.20.10.10.6-1.70.21.70.40.40.5-1.2
Intermittent access intake escalation 21.01.03.50.70.80.81.1-1.90.1-1.3-1.4-0.40.20.20.20.21.0-1.81.01.8-0.80.6-0.4-0.6
Intermitt. access day 1 inactive lever presses0.60.71.7-1.0-1.1-0.8-1.01.3-0.51.10.90.5-0.6-0.6-0.6-0.6-1.10.1-1.2-0.10.7-0.9-0.30.3
Intermitt. access day 15 inactive lever presses0.20.21.1-0.3-0.1-0.3-0.70.40.10.00.2-0.30.30.30.30.30.2-0.30.10.31.00.60.5-0.8
Intermitt. access escalation Index0.20.21.7-0.3-0.3-0.3-0.60.7-0.20.40.7-0.00.10.1-0.1-0.10.20.2-0.3-0.20.70.11.3-0.5
Intermittent access day 1 total infusions0.20.20.7-0.1-0.0-0.1-0.50.70.30.30.4-0.30.30.30.40.40.00.8-0.0-0.80.80.40.6-0.2
Intermittent access day 15 total infusions0.10.10.5-0.2-0.0-0.0-0.40.2-0.0-0.10.1-0.20.20.20.30.30.3-0.50.10.50.70.50.6-0.7
Intermittent access terminal intake (last 3 days)0.20.21.1-0.2-0.1-0.1-0.3-0.1-0.3-0.2-0.0-0.10.10.10.10.10.3-1.00.11.00.50.40.6-0.8
Intermittent access total infusions0.10.10.4-0.3-0.2-0.2-0.50.4-0.10.20.2-0.10.00.00.10.1-0.1-0.2-0.20.20.60.20.4-0.4
Intermittent access day 1 locomotion0.80.81.7-0.9-0.9-0.8-0.61.3-0.31.31.20.9-0.9-0.9-0.8-0.8-1.30.9-0.8-0.9-0.2-0.8-0.31.1
Intermittent access day 15 total locomotion0.60.61.6-0.9-0.9-0.9-1.30.9-0.90.60.50.3-0.2-0.2-0.2-0.2-0.3-1.2-1.01.21.3-0.30.7-0.9
Intermittent access total locomotion0.10.10.3-0.3-0.3-0.3-0.50.5-0.00.30.20.00.00.00.10.1-0.30.1-0.3-0.10.5-0.00.0-0.1
Intermittent access standard deviation0.20.21.5-0.3-0.2-0.0-0.2-0.2-0.5-0.1-0.2-0.0-0.1-0.1-0.2-0.20.1-1.2-0.31.20.3-0.10.3-0.6
Left kidney weight2.57.113.5-2.5-2.4-2.4-1.11.7-2.32.62.33.4-3.5-3.5-3.7-3.7-3.5-1.7-1.81.9-1.7-2.7-2.92.4
Right kidney weight3.810.820.2-2.9-3.0-2.8-1.12.0-2.73.22.64.2-4.2-4.2-4.4-4.4-4.5-1.5-2.41.5-2.5-3.8-3.93.6
Cocaine induced anxiety0.80.93.8-0.8-0.7-0.8-0.30.5-0.30.80.51.1-1.2-1.2-1.1-1.1-1.5-0.2-0.40.2-0.8-0.8-2.01.3
Post-drug Anxiety0.40.41.0-0.6-0.5-0.5-0.10.1-0.60.40.20.8-0.8-0.8-0.9-0.9-0.8-0.8-0.40.8-0.6-0.7-1.00.6
Baseline Anxiety0.20.20.8-0.4-0.3-0.3-0.40.2-0.60.20.30.2-0.2-0.2-0.2-0.20.2-0.8-0.30.80.3-0.10.9-0.7
Tail length0.30.83.5-0.9-0.9-1.0-1.10.5-1.10.50.50.6-0.5-0.5-0.6-0.6-0.4-1.9-0.91.90.7-0.40.0-0.8
Length with tail0.72.74.1-2.0-2.0-1.9-1.71.6-1.91.81.51.6-1.7-1.7-1.6-1.6-1.8-1.8-2.02.00.5-1.6-0.40.1
Length without tail0.81.73.3-1.6-1.7-1.4-1.31.8-1.41.81.61.2-1.3-1.3-1.1-1.1-1.5-0.2-1.80.40.4-1.50.40.5
Times rat made contact with spout0.40.40.8-0.6-0.6-0.6-0.20.5-0.50.70.80.9-0.9-0.9-0.9-0.9-0.8-0.1-0.30.1-0.6-0.6-0.30.8
Lifetime Intake0.10.10.20.20.20.30.10.00.3-0.1-0.1-0.40.30.30.40.40.10.40.1-0.40.30.30.3-0.1
Liver weight, left2.43.87.9-2.1-2.4-2.0-1.71.5-2.81.91.41.8-1.8-1.8-1.8-1.8-1.8-2.6-2.82.60.3-2.50.2-0.1
Liver weight, right1.42.44.5-1.3-1.4-1.3-0.40.8-1.41.51.11.9-2.0-2.0-1.9-1.9-2.1-0.7-1.40.7-1.3-2.1-1.61.7
Locomotor activity0.20.30.70.70.50.70.7-0.60.7-0.5-0.7-0.40.40.40.40.40.20.80.2-0.8-0.4-0.1-0.70.5
Locomotor testing distance0.40.61.21.00.90.90.9-0.81.1-0.8-0.8-0.60.60.60.80.80.51.10.9-1.0-0.40.5-0.50.4
Locomotor testing rearing1.01.52.81.11.21.20.5-0.91.5-1.3-1.2-1.51.51.51.71.71.40.81.2-0.90.81.60.3-0.9
Locomotion in novel chamber0.70.91.8-1.2-1.0-1.0-0.60.9-0.91.21.31.2-1.3-1.3-0.9-0.9-1.1-0.3-0.60.2-0.4-0.80.20.6
Locomotion in novel chamber post-restriction1.11.43.4-1.2-1.4-1.2-1.21.0-1.81.20.71.0-0.9-0.9-1.0-1.0-1.0-1.5-1.81.50.5-1.60.5-0.3
Fecal boli incidents, locomotor time 11.01.12.81.31.31.21.7-1.41.2-1.1-1.1-0.80.60.60.60.60.81.11.2-1.1-1.40.6-0.50.8
Change in fecal boli incidents, locomotor task3.12.94.4-2.1-2.1-2.1-1.81.7-2.01.81.71.9-1.7-1.7-1.8-1.8-1.7-2.0-1.91.80.5-1.6-0.2-0.0
Time >=10cm from walls, locomotor time 10.20.20.70.10.10.2-0.20.0-0.1-0.2-0.1-0.40.30.30.40.40.5-0.40.00.50.70.30.9-0.9
Bouts of movement, locomotor time 13.43.76.02.32.32.42.3-2.22.2-2.1-2.2-2.11.91.91.91.91.72.01.9-2.0-1.01.4-0.10.2
Total resting periods, locomotor time 13.23.55.22.22.22.32.0-1.92.2-2.0-2.0-2.12.02.01.91.91.82.01.9-2.0-0.51.70.1-0.1
Rest time, locomotor task time 10.00.00.1-0.1-0.1-0.2-0.30.3-0.00.20.20.0-0.0-0.0-0.2-0.2-0.10.4-0.1-0.30.30.10.1-0.0
Distance moved, locomotor task time 10.20.20.40.40.40.30.1-0.10.5-0.30.0-0.30.50.50.60.60.50.50.4-0.40.20.50.7-0.2
Vertical activity count, locomotor time 10.20.20.8-0.3-0.4-0.3-0.60.5-0.60.40.30.10.00.00.30.3-0.0-0.5-0.70.50.7-0.40.9-0.6
Time >=10cm from walls, locomotor time 29.910.516.5-3.8-3.9-3.7-3.33.8-3.84.03.53.4-3.3-3.3-3.2-3.2-3.7-2.3-4.12.30.8-3.6-0.10.8
Bouts of movement, locomotor time 20.30.32.7-0.3-0.4-0.1-0.50.7-0.70.50.4-0.20.10.10.10.10.0-0.1-1.1-0.00.8-0.71.6-0.6
Total resting periods, locomotor time 20.30.32.9-0.1-0.3-0.0-0.50.6-0.50.40.3-0.30.20.20.30.30.20.1-0.9-0.20.9-0.51.7-0.7
Rest time, locomotor task time 24.14.76.72.52.52.31.8-2.22.6-2.6-2.3-2.42.32.32.32.32.41.82.6-1.70.02.6-0.1-0.7
Distance moved, locomotor task time 22.02.33.7-1.8-1.8-1.7-1.51.8-1.51.91.91.8-1.6-1.6-1.6-1.6-1.8-0.9-1.60.80.2-1.6-0.10.6
Vertical activity count, locomotor time 24.54.98.2-2.8-2.7-2.5-2.62.9-2.82.82.72.1-2.0-2.0-1.8-1.8-2.0-1.9-2.71.81.4-2.11.2-0.3
Light reinforcement 11.32.48.7-1.8-1.8-1.9-2.22.9-0.82.22.61.1-1.0-1.0-0.9-0.9-1.40.9-1.6-0.81.5-0.71.10.2
Light reinforcement 20.60.91.90.70.80.70.2-0.21.2-0.7-0.5-1.11.11.11.41.40.91.10.8-1.30.71.20.6-0.5
Bone: marrow area0.10.20.9-0.3-0.3-0.3-0.40.1-0.50.10.20.2-0.1-0.1-0.1-0.10.1-1.0-0.31.00.4-0.10.5-0.6
Bone: maximum diameter0.81.42.3-1.5-1.5-1.5-1.41.4-1.51.41.41.1-1.1-1.1-1.1-1.1-1.0-1.2-1.41.20.5-1.10.7-0.2
Bone: maximum force1.72.84.7-2.1-2.0-2.2-1.81.9-1.81.92.11.9-1.8-1.8-1.8-1.8-1.7-1.6-1.41.60.3-1.20.20.2
Bone: maximum moment1.32.23.5-1.9-1.7-1.9-1.51.6-1.61.71.91.8-1.6-1.6-1.7-1.7-1.5-1.3-1.21.30.1-1.10.00.3
Mean time between licks in bursts0.91.22.61.41.41.41.5-1.61.2-1.4-1.5-1.00.80.80.80.80.80.71.2-0.7-0.90.7-0.80.3
Mean num. licks in bursts0.80.91.9-1.2-1.1-1.2-1.01.3-0.61.31.31.1-1.0-1.0-1.0-1.0-1.40.1-0.9-0.10.1-0.8-0.50.7
Cd content in liver0.20.20.5-0.4-0.4-0.3-0.10.3-0.60.50.40.5-0.6-0.6-0.6-0.6-0.5-0.2-0.60.2-0.3-0.70.00.3
Co content in liver0.40.51.80.60.70.71.2-1.00.4-0.5-0.60.1-0.3-0.3-0.3-0.3-0.00.30.9-0.4-1.30.1-1.00.9
Cu content in liver0.60.71.30.80.80.90.6-1.10.4-1.1-1.1-1.00.80.80.90.91.1-0.80.70.80.30.90.5-1.1
Fe content in liver2.42.97.70.60.80.7-0.60.11.2-1.0-0.4-2.22.32.32.32.32.10.50.5-0.52.52.32.8-2.5
K content in liver0.20.20.4-0.1-0.3-0.20.1-0.2-0.60.1-0.10.5-0.5-0.5-0.4-0.4-0.4-0.6-0.40.6-0.5-0.6-0.40.3
Mg content in liver0.70.73.7-0.6-0.7-0.7-0.3-0.1-1.30.30.30.9-1.0-1.0-0.8-0.8-0.3-1.9-0.41.9-0.4-0.50.1-0.3
Mn content in liver0.80.91.8-0.8-0.8-0.9-0.30.4-0.80.90.81.3-1.3-1.3-1.2-1.2-1.2-0.7-0.40.7-0.8-0.9-1.00.9
Na content in liver1.71.83.51.31.21.20.6-1.11.2-1.5-1.7-1.81.81.81.91.91.60.40.7-0.40.91.30.3-1.2
Rb content in liver3.84.78.5-2.1-2.1-2.2-1.21.2-2.72.02.02.7-2.9-2.9-2.8-2.8-2.2-2.5-1.52.6-1.1-2.2-0.70.9
Se content in liver0.20.21.1-0.5-0.4-0.5-0.40.2-0.50.20.50.5-0.5-0.5-0.4-0.4-0.1-1.0-0.01.00.00.00.2-0.3
Sr content in liver0.60.51.50.80.60.81.1-0.70.5-0.3-0.7-0.2-0.1-0.1-0.1-0.1-0.21.10.3-1.0-1.0-0.5-1.21.2
Zn content in liver0.50.61.50.80.60.80.4-0.80.5-0.9-1.2-1.01.01.01.01.00.8-0.00.10.00.40.50.0-0.7
Bone: minimum diameter1.32.44.7-1.0-1.1-1.00.10.6-1.21.41.12.0-2.2-2.2-2.2-2.2-2.1-0.3-0.90.3-1.8-2.1-1.62.1
Time in familiar zone, hab. session 11.51.42.81.51.41.61.3-1.41.0-1.4-1.7-1.41.31.31.41.41.30.70.8-0.8-0.20.60.1-0.3
Time in novel zone, hab. session 12.32.24.9-1.9-1.7-2.0-1.81.9-1.41.82.21.7-1.5-1.5-1.6-1.6-1.4-1.0-1.01.10.5-0.70.40.1
Total zone transitions, hab. session 10.50.71.71.10.81.01.2-1.00.8-0.8-1.3-0.70.60.60.60.60.31.10.2-1.1-0.7-0.1-1.00.7
Total locomotion distance, hab. session 10.50.71.90.90.70.91.1-0.90.8-0.6-1.1-0.50.40.40.40.40.01.10.3-1.1-0.8-0.2-1.41.0
Locomotion velocity, hab. session 10.71.02.41.21.01.21.4-1.01.1-0.8-1.4-0.70.60.60.60.60.11.50.4-1.5-0.9-0.1-1.51.1
Time in familiar zone, hab. session 20.10.10.70.20.00.1-0.00.1-0.20.0-0.0-0.30.20.20.20.20.30.3-0.4-0.10.3-0.20.9-0.3
Time in novel zone, hab. session 20.60.61.2-0.9-0.7-0.8-0.50.6-0.40.70.91.1-1.0-1.0-1.1-1.1-1.0-0.7-0.10.6-0.4-0.2-0.80.5
Total zone transitions, hab. session 20.40.52.10.80.60.81.1-1.10.4-0.7-1.2-0.30.10.10.20.2-0.00.40.3-0.4-1.0-0.3-1.50.8
Total locomotion distance, hab. session 20.10.10.90.0-0.00.10.2-0.10.00.0-0.30.0-0.1-0.1-0.1-0.1-0.40.2-0.2-0.2-0.3-0.4-0.90.5
Locomotion velocity, hab. session 20.10.10.90.30.10.30.4-0.20.2-0.1-0.5-0.20.10.10.10.1-0.30.5-0.2-0.5-0.3-0.4-1.00.6
Novel to familiar place preference ratio1.71.73.3-1.7-1.7-1.6-1.61.8-1.31.71.71.3-1.2-1.2-1.2-1.2-1.5-0.6-1.60.50.6-1.20.20.3
Novelty place preference1.61.63.0-1.7-1.6-1.5-1.51.7-1.21.71.71.3-1.2-1.2-1.2-1.2-1.5-0.6-1.50.50.5-1.20.10.3
Time in novel zone, NPP test1.51.63.0-1.7-1.6-1.5-1.61.7-1.21.61.61.3-1.1-1.1-1.1-1.1-1.4-0.7-1.50.60.6-1.10.30.2
Total zone transitions, NPP test1.21.74.71.61.51.62.0-2.21.1-1.7-2.0-0.90.70.70.70.70.80.41.4-0.4-1.40.5-1.80.6
Total locomotion distance, NPP test0.71.05.90.80.80.81.5-1.40.6-0.8-1.20.1-0.3-0.3-0.3-0.3-0.30.10.9-0.1-1.7-0.2-2.41.3
Locomotion velocity, NPP test0.81.26.80.90.90.91.7-1.60.7-0.9-1.30.1-0.3-0.3-0.3-0.3-0.30.31.0-0.3-1.9-0.2-2.61.5
Intraocular pressure1.11.63.71.41.51.61.3-0.91.6-1.1-0.7-1.21.11.11.01.01.21.91.5-1.9-0.41.20.60.2
Delta distance traveled before/after self-admin0.30.30.90.40.30.3-0.1-0.10.2-0.4-0.2-0.70.50.50.70.70.60.10.1-0.00.80.50.9-0.8
Delta ambulatory time before/after self-admin0.30.31.00.40.30.3-0.30.20.4-0.3-0.1-0.80.70.70.80.80.50.50.1-0.41.00.60.8-0.7
Parametrial fat weight0.10.20.8-0.3-0.6-0.3-0.20.5-0.30.50.20.4-0.4-0.4-0.3-0.3-0.80.2-0.9-0.0-0.1-0.9-0.70.6
Pavlov. Cond. lever latency0.20.31.3-0.5-0.4-0.4-0.40.3-0.70.30.60.4-0.2-0.2-0.2-0.20.2-1.1-0.31.00.3-0.01.1-0.7
Pavlov. Cond. magazine entry latency0.70.93.5-1.1-1.1-1.3-1.71.9-0.31.21.30.3-0.3-0.3-0.3-0.3-0.90.5-1.0-0.51.4-0.10.3-0.2
Pavlov. Cond. change in total contacts0.20.20.9-0.4-0.4-0.6-0.90.4-0.10.10.1-0.10.10.10.10.1-0.1-0.6-0.20.71.00.3-0.2-0.6
Pavlov. Cond. index score0.20.21.40.20.10.1-0.20.40.60.0-0.1-0.40.40.40.30.3-0.11.2-0.0-1.10.40.2-0.50.3
Pavlov. Cond. latency score0.20.31.80.20.0-0.0-0.10.40.50.2-0.0-0.20.10.10.10.1-0.41.4-0.2-1.20.1-0.2-0.80.7
Pavlov. Cond. lever contacts0.30.41.30.60.50.50.5-0.30.8-0.4-0.7-0.50.40.40.30.3-0.11.10.3-1.1-0.20.1-1.10.7
Pavlov. Cond. magazine entry number0.40.51.90.80.81.01.2-1.40.2-0.9-1.0-0.40.30.30.30.30.7-0.50.60.4-0.90.0-0.0-0.0
Pavlov. Cond. intertrial magazine entries0.70.94.20.40.40.50.0-0.50.0-0.8-0.5-1.01.11.11.01.01.5-0.80.20.60.90.92.0-1.7
Pavlov. Cond. lever-magazine prob. diff.0.20.21.20.40.30.20.10.00.7-0.2-0.3-0.50.40.40.40.40.01.10.3-1.00.20.4-0.60.3
Pavlov. Cond. response bias0.20.21.0-0.00.1-0.2-0.60.40.5-0.10.0-0.50.50.50.50.50.20.50.1-0.41.00.70.0-0.5
Pavlov. Cond. lever latency3.44.610.22.82.72.82.9-3.22.2-2.8-3.0-1.91.71.71.71.71.91.02.5-1.0-1.51.5-1.30.2
Pavlov. Cond. magazine entry latency1.71.96.2-1.7-1.5-1.7-2.52.3-0.91.41.90.3-0.0-0.0-0.1-0.1-0.3-0.5-1.20.52.40.32.1-1.5
Pavlov. Cond. change in total contacts1.62.27.1-1.8-1.7-1.9-2.72.4-1.21.51.80.4-0.1-0.1-0.2-0.2-0.5-0.8-1.80.82.5-0.11.9-1.5
Pavlov. Cond. index score2.53.39.6-2.3-2.1-2.3-3.12.9-1.52.02.50.8-0.5-0.5-0.6-0.6-0.8-1.1-1.91.02.6-0.32.3-1.6
Pavlov. Cond. latency score2.22.78.1-2.1-1.9-2.1-2.82.6-1.41.82.20.7-0.5-0.5-0.5-0.5-0.7-1.1-1.71.12.4-0.12.1-1.5
Pavlov. Cond. lever contacts2.73.69.5-2.4-2.4-2.5-2.83.1-1.92.52.71.4-1.2-1.2-1.2-1.2-1.5-0.5-2.50.51.7-1.31.7-0.4
Pavlov. Cond. magazine entry number1.82.16.71.81.71.92.6-2.31.1-1.5-1.9-0.50.30.30.30.30.41.01.3-1.0-2.3-0.1-1.91.5
Pavlov. Cond. intertrial magazine entries0.60.83.80.20.10.21.1-0.7-0.30.1-0.20.8-1.0-1.0-1.0-1.0-0.70.10.20.0-1.9-1.0-1.41.6
Pavlov. Cond. lever-magazine prob. diff.2.43.19.1-2.2-2.1-2.3-3.02.8-1.51.92.40.7-0.4-0.4-0.5-0.5-0.7-1.0-1.81.02.6-0.22.3-1.6
Pavlov. Cond. response bias3.34.511.9-2.7-2.6-2.7-3.43.5-2.02.62.91.2-0.9-0.9-1.0-1.0-1.3-0.9-2.60.92.6-1.02.4-1.2
Time in closed arm before self-admin1.61.83.51.61.51.61.2-1.01.5-1.2-1.2-1.71.51.51.41.41.41.81.1-1.90.21.20.7-0.3
Time in closed arm after self-admin1.31.32.50.90.90.8-0.00.01.2-0.7-0.3-1.51.51.51.31.31.31.40.9-1.31.31.61.3-1.0
Time in open arm before self-admin0.40.41.0-0.5-0.6-0.7-0.40.6-0.60.81.00.8-1.0-1.0-0.8-0.8-0.7-0.1-0.40.2-0.5-0.60.10.5
Time in open arm after self-admin2.62.88.9-1.9-1.8-1.9-1.50.9-2.21.31.41.9-1.8-1.8-1.5-1.5-1.1-3.0-1.52.90.1-1.40.5-0.5
Bone: periosteal estimation0.61.22.0-1.3-1.2-1.3-1.01.0-1.41.11.21.2-1.2-1.2-1.2-1.2-0.9-1.3-1.01.30.0-1.00.3-0.0
Bone: periosteal perimeter0.61.01.9-1.0-0.9-0.9-0.40.7-1.01.01.01.3-1.4-1.4-1.4-1.4-1.2-0.6-0.60.6-0.7-1.1-0.50.8
Bone: post-yield work0.10.21.50.30.20.30.5-0.60.2-0.4-0.7-0.0-0.0-0.0-0.1-0.1-0.2-0.20.20.2-0.5-0.2-1.20.4
Progressive ratio test 1 active lever presses0.30.41.8-0.4-0.3-0.3-0.90.9-0.00.40.5-0.30.30.30.40.40.10.1-0.3-0.11.30.41.3-0.8
Progressive ratio test 1 breakpoint0.30.31.6-0.2-0.1-0.1-0.70.60.10.10.2-0.40.50.50.50.50.20.1-0.2-0.11.30.51.1-0.8
Progressive ratio test 1 inactive lever presses0.30.31.9-0.2-0.00.0-0.70.60.3-0.00.2-0.60.60.60.70.70.40.1-0.0-0.11.40.70.8-0.9
Progressive ratio test 2 active lever presses0.60.73.1-0.00.10.0-0.80.50.4-0.2-0.0-0.90.90.91.01.00.80.10.2-0.11.81.11.2-1.4
Progressive ratio test 2 breakpoint0.70.84.2-0.3-0.2-0.3-1.20.90.10.10.4-0.70.80.80.80.80.60.0-0.1-0.02.11.01.7-1.5
Progressive ratio test 2 inactive lever presses0.20.31.3-0.5-0.4-0.5-0.90.7-0.10.30.5-0.10.10.10.20.20.1-0.5-0.10.51.20.50.6-0.9
Incentive Sensitization - Responses0.10.10.4-0.3-0.2-0.4-0.50.2-0.20.10.30.10.00.00.00.00.2-0.50.00.50.50.30.6-0.6
Incentive Sensitization - Breakpoint0.10.10.5-0.3-0.3-0.4-0.60.4-0.20.10.40.00.00.00.10.10.2-0.5-0.00.50.70.30.7-0.7
Sum of active levers in priming session hrs 5-60.20.20.40.30.40.30.3-0.70.2-0.6-0.6-0.30.20.20.30.30.5-0.60.40.5-0.00.4-0.1-0.5
Progressive ratio0.20.30.70.60.30.70.3-0.30.2-0.4-0.8-0.70.80.80.50.50.50.4-0.5-0.20.4-0.20.2-0.3
Food seeking constrained by brief footshock0.00.00.10.1-0.0-0.00.00.10.00.10.00.0-0.0-0.0-0.0-0.0-0.20.2-0.2-0.2-0.1-0.3-0.30.3
Seeking ratio, punishment vs. effort0.10.10.4-0.10.1-0.2-0.00.20.30.10.40.2-0.2-0.20.00.0-0.10.30.6-0.4-0.20.40.00.3
Retroperitoneal fat weight3.611.818.9-4.3-4.3-4.3-4.14.3-4.14.14.13.3-3.1-3.1-3.0-3.0-3.3-2.8-4.32.91.6-3.21.3-0.2
Reaction time number correct2.63.89.2-2.2-2.2-2.2-1.91.6-2.61.81.81.9-1.8-1.8-2.0-2.0-1.5-2.9-2.03.00.5-1.60.5-0.5
Reaction time mean minus median0.71.01.8-1.1-1.2-1.2-1.01.1-1.21.31.11.2-1.0-1.0-0.7-0.7-1.2-0.4-1.30.50.0-1.30.10.4
Reaction time mean minus median AUC2.33.04.9-2.0-2.1-2.2-1.71.9-2.02.11.92.1-1.9-1.9-1.7-1.7-2.0-1.1-1.91.1-0.0-1.9-0.10.7
Reaction time num false alarms0.00.00.30.10.1-0.0-0.10.10.3-0.00.1-0.00.10.1-0.3-0.3-0.00.20.4-0.20.10.4-0.50.1
Reaction time num false alarms AUC0.10.10.50.30.30.1-0.20.10.4-0.2-0.1-0.40.50.50.20.20.40.20.4-0.20.60.70.1-0.4
Reaction time trials correct on left2.63.89.2-2.2-2.2-2.2-1.91.6-2.61.81.81.9-1.8-1.8-2.0-2.0-1.5-2.9-2.03.00.5-1.60.5-0.5
Reaction time trials on left2.73.89.1-2.2-2.2-2.2-2.01.6-2.61.81.81.9-1.8-1.8-1.9-1.9-1.5-2.9-2.03.00.6-1.60.5-0.5
Reaction time mean0.71.02.70.60.60.6-0.20.00.6-0.6-0.4-1.21.31.31.41.41.30.70.3-0.71.31.01.6-1.3
Reaction time mean AUC0.30.41.80.30.30.3-0.20.20.2-0.2-0.1-0.80.90.90.90.90.80.50.1-0.51.00.61.4-0.9
Median of all reaction times1.82.54.61.31.41.40.4-0.61.4-1.3-1.0-2.12.12.12.12.12.11.21.1-1.21.51.81.8-1.7
Reaction time omissions0.30.40.9-0.7-0.6-0.6-0.60.9-0.30.90.90.7-0.8-0.8-0.6-0.6-0.90.4-0.5-0.4-0.0-0.5-0.30.7
Reaction time false alarm rate0.81.12.51.21.21.00.7-0.61.5-0.9-0.8-1.11.11.10.90.90.91.61.2-1.60.21.2-0.20.0
Reaction time premature initiation rate0.91.22.80.70.60.6-0.30.31.1-0.5-0.6-1.51.51.51.51.50.91.50.0-1.41.71.00.8-1.0
Reaction time premature initiations0.40.63.6-0.5-0.6-0.6-1.41.1-0.30.50.5-0.50.50.50.50.50.1-0.1-0.90.31.90.21.0-1.2
Std. dev. reaction times0.60.81.6-1.0-1.1-1.1-1.01.3-1.01.31.31.0-0.9-0.9-0.6-0.6-0.9-0.1-1.20.10.2-1.00.60.3
Reaction time trials completed2.73.89.1-2.2-2.2-2.2-2.01.6-2.61.81.81.9-1.8-1.8-1.9-1.9-1.5-2.9-2.03.00.6-1.60.5-0.5
Reaction time trials AUC2.63.89.4-2.3-2.2-2.2-2.21.8-2.61.81.91.7-1.6-1.6-1.7-1.7-1.3-3.0-2.13.11.0-1.40.9-0.9
Run reversals in cocaine runway, females0.30.32.1-0.1-0.10.0-0.1-0.5-0.4-0.4-0.5-0.10.10.10.10.10.2-1.5-0.01.40.30.1-0.6-0.8
Run reversals in cocaine runway, males1.31.22.11.51.41.21.2-1.31.4-1.3-1.1-1.21.01.01.11.11.20.81.4-0.6-0.31.3-0.2-0.2
Latency to leave start box in cocaine runway0.30.31.9-0.1-0.3-0.1-0.80.7-0.20.20.1-0.50.60.60.40.40.30.2-0.7-0.11.40.01.1-0.9
Latency to leave start box in cocaine runway, F0.20.20.90.50.30.50.6-0.30.4-0.2-0.4-0.20.30.3-0.1-0.10.00.90.1-0.9-0.4-0.2-0.50.6
Latency to leave start box in cocaine runway, M1.81.88.3-1.0-1.0-1.0-2.11.6-0.80.60.8-0.50.70.70.70.70.4-1.0-1.31.02.90.32.3-2.3
Std. dev. time between licks in bursts1.41.62.9-1.0-1.1-1.0-0.20.6-1.11.21.01.7-1.7-1.7-1.7-1.7-1.7-0.4-0.90.4-1.4-1.6-1.21.6
Total sessions with >9 infusions0.60.73.20.30.30.51.0-0.20.60.2-0.00.2-0.4-0.4-0.3-0.3-0.81.60.3-1.6-1.4-0.5-1.21.8
Short access day 1 total inactive lever presses0.20.20.5-0.5-0.6-0.4-0.30.5-0.50.50.40.4-0.5-0.5-0.5-0.5-0.7-0.3-0.70.3-0.0-0.7-0.60.2
Short access day 10 total inactive lever presses0.91.02.5-1.2-1.1-1.3-1.50.9-0.80.70.60.7-0.6-0.6-0.6-0.6-0.9-1.6-0.81.61.0-0.2-1.2-0.5
Short access day 1 total infusions0.70.82.01.01.01.21.2-0.81.1-0.7-0.8-0.80.60.60.70.70.41.40.8-1.4-0.70.4-0.50.7
Short access day 10 total infusions0.20.20.6-0.4-0.4-0.2-0.30.8-0.20.60.40.1-0.2-0.2-0.0-0.0-0.60.6-0.7-0.60.3-0.60.10.4
Short access total infusions0.10.20.90.30.30.50.4-0.00.4-0.0-0.1-0.30.20.20.30.3-0.00.9-0.0-0.9-0.2-0.10.10.4
Short access day 1 locomotion0.30.41.70.50.50.60.30.00.7-0.2-0.2-0.70.60.60.60.60.31.30.3-1.30.20.40.20.1
Short access day 10 total locomotion0.80.94.70.70.60.71.6-1.30.4-0.5-0.80.4-0.5-0.5-0.4-0.4-0.40.30.7-0.3-2.2-0.5-1.61.6
Short access total locomotion0.50.52.2-0.2-0.2-0.10.20.50.10.70.40.5-0.6-0.6-0.5-0.5-1.01.2-0.3-1.2-0.8-0.8-0.81.5
One hour access (0.3 mA shock)0.91.14.5-0.00.20.0-0.7-0.2-0.1-0.7-0.3-0.80.80.80.90.91.2-1.60.41.61.61.21.7-2.1
Compulsive drug intake0.40.41.90.10.10.1-0.4-0.1-0.3-0.3-0.2-0.50.60.60.60.60.9-0.8-0.10.81.00.41.2-1.4
One hour access (shock baseline)0.10.10.5-0.10.1-0.0-0.40.30.3-0.00.1-0.30.30.30.40.40.20.10.3-0.10.70.70.4-0.4
Social response proportion2.12.311.8-1.3-1.1-1.2-2.62.1-0.70.81.1-0.50.60.60.90.90.4-0.8-1.10.93.40.92.4-2.5
Social responses2.02.610.50.10.30.0-1.61.10.7-0.30.4-1.71.91.91.81.81.70.60.2-0.53.22.02.9-2.7
Social time0.40.63.3-0.3-0.4-0.4-1.00.7-0.30.20.4-0.40.60.60.50.50.6-0.2-0.70.21.50.11.8-1.3
Soleus weight0.20.52.7-0.1-0.1-0.1-0.60.4-0.1-0.10.1-0.60.80.80.70.70.8-0.2-0.30.11.20.51.6-1.2
Bone: stiffness1.11.83.0-1.7-1.7-1.7-1.61.5-1.51.51.51.4-1.3-1.3-1.3-1.3-1.3-1.4-1.41.40.5-1.0-0.0-0.0
Tibialis anterior weight0.41.35.4-1.1-1.1-1.2-1.81.4-1.00.71.0-0.10.40.40.40.40.4-1.0-1.21.02.00.22.3-1.8
Time to tail flick, vehicle, before self-admin0.60.61.5-0.3-0.5-0.40.20.1-0.60.60.20.8-1.0-1.0-0.9-0.9-1.1-0.1-0.70.0-1.0-1.2-0.81.2
Time to tail flick, vehicle, after self-admin0.20.20.7-0.5-0.4-0.4-0.10.1-0.70.30.40.5-0.5-0.5-0.5-0.5-0.3-0.8-0.20.8-0.3-0.40.3-0.0
Time to tail flick, test, before self-admin0.60.61.1-0.8-0.9-0.9-0.91.0-0.71.01.00.6-0.8-0.8-1.0-1.0-1.0-0.2-0.90.20.3-0.70.10.2
Time to tail flick, test, after self-admin0.60.61.2-0.8-0.9-0.9-0.80.8-1.00.90.80.7-0.8-0.8-0.8-0.8-0.8-0.7-1.10.80.3-0.90.2-0.0
Delta time to tail flick, vehicle, before/after SA0.70.73.2-1.0-0.9-0.9-1.10.6-1.00.50.70.5-0.3-0.3-0.4-0.4-0.1-1.8-0.61.70.8-0.10.7-1.0
Delta time to tail flick, test, before/after SA0.10.00.1-0.2-0.2-0.2-0.00.1-0.30.30.20.3-0.2-0.2-0.2-0.2-0.10.0-0.3-0.0-0.3-0.40.20.2
Tibia length0.82.25.0-1.3-1.3-1.3-0.61.3-0.81.71.41.8-1.9-1.9-1.8-1.8-2.20.4-1.0-0.3-0.9-1.5-1.71.9
Ambulatory time before self-admin0.20.20.6-0.4-0.5-0.5-0.20.5-0.30.60.40.6-0.4-0.4-0.5-0.5-0.60.3-0.5-0.4-0.4-0.7-0.40.8
Ambulatory time after self-admin0.40.41.10.40.40.3-0.2-0.20.3-0.5-0.3-0.70.90.90.80.80.9-0.10.30.10.90.81.0-1.1
Bone: tissue strength0.30.31.2-0.4-0.4-0.5-0.10.2-0.30.40.30.8-0.7-0.7-0.8-0.8-0.8-0.3-0.10.3-0.6-0.5-1.10.7
Total heroin consumption0.40.52.50.50.50.41.1-1.00.4-0.5-0.60.3-0.3-0.3-0.2-0.2-0.20.20.7-0.4-1.6-0.3-1.51.2
Bone: trabecular number1.32.04.9-1.6-1.7-1.6-1.41.0-1.91.21.01.4-1.3-1.3-1.4-1.4-1.2-2.2-1.62.20.3-1.3-0.0-0.3
Bone: trabecular spacing0.70.95.00.80.90.80.60.01.3-0.30.1-0.60.70.70.60.60.52.20.9-2.2-0.20.80.40.6
Bone: trabecular thickness0.50.61.40.60.50.60.2-0.60.2-0.8-0.8-1.00.90.91.01.01.1-0.50.20.50.60.61.0-1.2
Bone: trabecular tissue density2.63.67.72.12.12.11.6-2.61.5-2.7-2.8-2.02.02.02.02.02.3-0.62.00.60.12.0-0.4-1.4
Water consumed over 24 hours0.10.21.1-0.10.0-0.1-0.40.30.1-0.00.2-0.30.30.30.30.30.4-0.10.10.10.70.51.0-0.8
Number of responses in last shaping day0.30.42.10.50.50.60.6-0.10.7-0.1-0.1-0.40.30.30.30.3-0.01.50.4-1.5-0.40.2-0.40.7