Sptbn5

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 PL intron excision ratio chr3_127471321_127471833 0.07 0.04 1.2e-08 0.07 0.07 0.07 0.07 1.7e-08 1.7e-08 8.7e-08 2.0e-08
2 IC isoform ratio XM_039106497.2 0.12 0.07 4.3e-04 0.12 0.07 0.08 0.09 9.2e-06 6.2e-04 4.0e-04 1.8e-04
3 NAcc intron excision ratio chr3_127471321_127471833 0.07 0.04 1.2e-10 0.07 0.07 0.07 0.07 1.7e-11 1.5e-10 8.2e-11 1.0e-10
4 Brain intron excision ratio chr3_127470788_127470871 0.04 0.03 3.8e-03 0.03 0.02 0.01 0.02 1.2e-03 9.1e-03 1.7e-02 7.0e-03
5 IC isoform ratio XM_039106500.2 0.11 0.07 1.9e-03 0.08 0.06 0.06 0.08 2.4e-04 1.1e-03 1.2e-03 3.7e-04
6 NAcc intron excision ratio chr3_127467945_127470706 0.02 0.01 4.9e-03 0.02 0.01 0.02 0.01 1.5e-03 1.8e-03 7.4e-04 1.8e-03
7 Brain gene expression Sptbn5 0.25 0.09 0.0e+00 0.25 0.24 0.24 0.25 3.9e-23 1.2e-22 2.0e-22 1.9e-23
8 IC intron excision ratio chr3_127471321_127471833 0.16 0.08 5.4e-06 0.12 0.12 0.12 0.13 9.0e-06 1.4e-05 1.4e-05 5.9e-06
9 PL intron excision ratio chr3_127470972_127471250 0.02 0.01 2.4e-03 0.02 0.02 0.01 0.02 5.9e-03 5.2e-03 9.0e-03 5.2e-03
10 IC intron excision ratio chr3_127467945_127470706 0.12 0.06 8.9e-05 0.09 0.08 0.07 0.09 2.1e-04 2.4e-04 7.5e-04 1.9e-04
11 IL gene expression Sptbn5 0.47 0.17 8.9e-07 0.18 0.16 0.14 0.14 3.3e-05 1.4e-04 2.8e-04 2.5e-04
12 PL intron excision ratio chr3_127467945_127470706 0.04 0.02 1.8e-05 0.04 0.04 0.04 0.03 2.3e-05 5.5e-05 5.9e-05 1.2e-04
13 PL isoform ratio XM_039106497.2 0.04 0.02 5.3e-05 0.04 0.03 0.03 0.04 3.1e-05 1.4e-04 1.4e-04 7.8e-05
14 OFC gene expression Sptbn5 0.33 0.16 4.5e-05 0.14 0.13 0.1 0.12 3.7e-04 6.4e-04 2.2e-03 7.9e-04
15 PL gene expression Sptbn5 0.28 0.1 0.0e+00 0.32 0.35 0.35 0.34 4.3e-36 2.3e-39 3.3e-39 6.3e-39
16 BLA gene expression Sptbn5 0.26 0.1 2.0e-12 0.19 0.18 0.19 0.13 2.6e-10 1.2e-09 1.7e-10 1.7e-07
17 BLA isoform ratio XM_039106497.2 0.06 0.04 4.1e-03 0.06 0.01 0.03 0.03 6.8e-04 6.9e-02 9.1e-03 1.5e-02
18 Adipose mRNA stability Sptbn5 0.09 0.05 5.7e-04 0.03 0.02 0.03 0.03 2.2e-04 3.1e-03 5.4e-04 8.1e-04
19 PL mRNA stability Sptbn5 0.05 0.03 1.3e-03 0.01 0.02 0 0.01 2.2e-02 5.9e-03 9.6e-02 7.1e-03
20 Brain mRNA stability Sptbn5 0.21 0.08 5.6e-16 0.1 0.18 0.18 0.18 2.5e-09 3.2e-16 1.4e-16 1.9e-16
21 Liver isoform ratio XM_039106500.2 0.03 0.02 6.8e-03 0 0 0 0 1.1e-01 1.2e-01 8.3e-02 1.7e-01
22 IC gene expression Sptbn5 0.3 0.11 4.0e-10 0.19 0.22 0.2 0.2 2.7e-08 2.1e-09 8.3e-09 7.8e-09
23 Liver gene expression Sptbn5 0.14 0.06 1.1e-16 0.15 0.15 0.15 0.15 3.2e-16 4.9e-16 2.4e-16 3.0e-16
24 NAcc gene expression Sptbn5 0.03 0.02 3.2e-03 0.01 0.01 0.01 0 5.2e-03 3.8e-02 6.6e-03 5.1e-02
25 Liver intron excision ratio chr3_127471937_127472045 0.04 0.02 1.7e-03 -0 0.01 0 0 5.0e-01 1.7e-02 2.8e-01 1.6e-01

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25
Bone: apparent density0.71.32.41.21.21.21.2-1.2-1.31.21.41.4-1.61.3-1.21.31.21.21.41.4-1.30.40.4-0.50.90.0-0.30.3
Area under the delay curve2.12.47.00.60.60.60.6-0.6-0.61.21.31.8-1.61.9-0.61.91.91.91.91.40.2-1.7-1.8-2.02.12.61.12.6
BMI with tail3.913.519.54.34.24.14.1-4.1-4.24.34.44.3-4.34.4-4.14.34.24.14.24.4-3.31.71.60.53.60.01.11.2
BMI without tail5.316.323.94.94.84.74.8-4.8-4.54.54.94.7-4.74.7-4.24.54.64.44.54.5-4.42.12.30.53.4-0.60.20.7
Body weight4.821.230.65.55.35.35.3-5.3-5.45.35.55.2-5.55.3-5.25.15.15.15.25.2-4.22.72.50.84.4-0.61.51.1
Weight adjusted by age1.01.52.41.21.41.51.5-1.5-1.11.51.51.3-1.31.3-1.31.41.51.41.21.0-0.50.70.7-0.31.5-0.01.30.6
Bone surface0.91.63.71.51.51.41.5-1.5-1.91.51.41.0-1.51.0-1.80.90.90.81.11.2-1.61.21.20.90.5-0.9-0.4-0.7
Bone volume0.91.63.11.61.51.51.5-1.5-1.71.71.41.2-1.51.2-1.71.11.10.91.11.1-1.61.11.10.70.7-0.7-0.2-0.5
Breakpoint value in progressive ratio session0.30.41.1-0.6-0.5-0.6-0.50.50.4-0.2-0.7-0.60.8-0.60.3-0.7-0.5-0.9-0.5-0.9-0.0-0.10.10.4-0.9-0.2-1.0-0.8
Number of licking bursts0.20.41.8-0.7-0.7-0.6-0.70.70.4-0.4-0.7-0.30.6-0.60.1-0.6-0.6-0.9-0.6-0.9-0.4-0.4-0.30.1-1.00.1-1.3-0.7
Context. condit. distance diff. score1.92.37.22.02.02.02.0-2.0-1.41.51.51.5-1.31.2-1.11.31.21.00.90.8-2.71.61.80.90.4-1.4-1.0-1.1
Locomotion velocity, session 13.13.45.9-2.3-2.3-2.3-2.32.32.3-2.2-1.8-1.61.6-1.42.4-1.5-1.4-1.2-1.4-1.22.4-2.2-2.2-1.5-0.81.60.11.1
Locomotion distance, session 11.41.84.1-1.6-1.6-1.6-1.61.61.9-1.7-1.2-0.90.9-0.92.0-0.9-0.9-0.8-1.0-0.81.4-1.7-1.6-1.7-0.61.2-0.20.9
Locomotion velocity, session 21.31.54.60.10.10.10.1-0.10.00.41.01.5-1.21.50.41.41.41.41.31.70.0-1.7-1.7-2.11.32.10.12.0
Locomotion distance, session 20.50.72.0-0.9-0.9-1.0-1.01.01.2-1.2-0.6-0.40.5-0.51.4-0.5-0.5-0.5-0.6-0.30.3-1.1-1.0-1.4-0.60.7-0.80.3
Locomotion velocity, session 30.50.62.7-0.5-0.5-0.5-0.60.60.50.10.00.6-0.20.50.50.50.50.20.20.50.5-1.4-1.5-1.50.51.6-0.11.1
Locomotion distance, session 30.30.32.4-0.2-0.2-0.2-0.20.20.50.1-0.20.20.3-0.10.8-0.0-0.2-0.7-0.8-0.4-0.9-0.4-0.2-0.0-0.70.1-1.6-0.7
Stereotopy head waving bouts, day 33.03.56.01.91.81.82.0-2.0-1.82.32.22.2-2.32.3-1.52.32.52.42.22.2-0.60.30.2-0.62.50.81.61.6
Stereotopy head waving duration, day 33.54.27.91.61.51.51.6-1.6-1.72.12.32.5-2.42.6-1.62.62.72.82.82.7-0.2-0.5-0.7-1.42.81.71.72.5
Locomotion velocity, session 70.20.31.10.60.60.60.6-0.60.10.50.50.8-0.40.60.70.60.60.3-0.20.2-1.1-0.10.2-0.50.2-0.0-0.7-0.1
Locomotion distance, session 70.30.41.60.30.30.30.3-0.30.3-0.2-0.1-0.20.3-0.40.6-0.4-0.3-0.5-0.7-0.6-1.20.70.90.2-0.8-1.1-1.3-1.2
Stereotopy head waving bouts, day 70.10.10.7-0.3-0.3-0.3-0.20.20.00.1-0.2-0.30.1-0.1-0.0-0.1-0.2-0.1-0.1-0.10.8-0.2-0.20.20.20.30.80.3
Stereotopy head waving duration, day 70.10.11.20.0-0.00.0-0.00.0-0.40.4-0.0-0.2-0.00.1-0.40.0-0.1-0.00.00.10.80.20.10.60.40.01.10.2
Locomotion velocity, session 82.12.55.71.51.31.41.3-1.3-0.71.41.82.4-1.82.2-0.42.32.22.11.82.0-1.3-0.6-0.5-1.71.81.20.11.6
Locomotion distance, session 80.60.84.21.21.11.11.1-1.1-0.40.51.01.1-0.90.80.10.80.80.60.40.5-2.10.60.7-0.60.1-0.6-1.4-0.6
Degree of sensitization distance0.50.52.40.20.20.20.2-0.2-0.0-0.4-0.3-1.00.6-0.9-0.4-0.8-0.7-0.4-0.4-0.70.21.31.30.9-0.5-1.50.5-1.0
Degree of sensitization stereotypy0.40.41.5-0.3-0.2-0.2-0.30.30.1-0.3-0.6-0.90.7-0.70.1-0.8-0.9-0.9-0.9-0.80.50.70.71.2-0.6-0.80.4-0.9
Conditioned locomotion1.41.62.41.51.51.51.5-1.5-1.51.31.51.5-1.41.4-1.31.41.41.41.51.2-1.50.70.80.41.0-0.2-0.10.2
Cocaine response after cond. corrected1.51.83.4-1.8-1.8-1.8-1.81.81.3-1.2-1.4-0.71.2-1.01.0-1.0-1.0-1.3-1.0-1.00.4-1.7-1.7-0.9-1.31.2-1.8-0.1
Cocaine response after cond. not corrected2.22.55.1-2.1-2.2-2.1-2.12.11.8-1.6-1.6-0.81.3-1.11.4-1.1-1.1-1.3-1.0-1.10.8-2.3-2.2-1.7-1.31.6-1.70.4
Cocaine response before conditioning0.30.43.0-0.2-0.4-0.4-0.40.40.9-0.60.0-0.1-0.10.10.90.10.10.30.00.10.9-0.7-0.7-1.70.40.70.71.0
Saline control response2.53.35.42.32.32.22.3-2.3-2.12.02.11.4-1.91.7-1.91.71.71.91.71.8-0.71.81.70.92.0-0.81.90.4
Bone: connectivity density0.50.81.70.90.90.90.9-0.9-1.20.81.10.6-1.30.8-1.20.70.71.01.01.1-0.20.70.6-0.30.9-0.30.90.3
Bone: cortical apparent density1.52.14.7-0.8-0.8-0.8-0.70.70.5-0.9-1.5-1.91.7-1.90.1-1.9-1.9-2.0-1.8-1.90.11.01.11.6-1.9-1.7-0.8-2.2
Bone: cortical area1.72.53.91.91.81.81.8-1.8-2.01.91.81.8-1.91.8-1.91.81.81.71.81.8-1.30.80.80.71.6-0.10.60.5
Bone: cortical porosity1.61.86.8-1.4-1.3-1.3-1.41.41.6-1.1-0.50.40.30.11.70.20.20.10.1-0.00.5-2.5-2.4-2.60.02.2-0.91.6
Bone: cortical porosity0.91.04.7-0.5-0.4-0.5-0.50.50.8-0.20.20.9-0.40.81.00.80.80.70.60.60.1-1.8-1.8-2.20.71.9-0.41.6
Bone: cortical thickness1.22.03.41.51.41.41.4-1.4-1.41.51.61.8-1.91.8-1.31.81.81.71.71.8-0.90.10.1-0.41.60.60.51.0
Bone: cortical thickness0.10.21.5-0.4-0.3-0.3-0.30.3-0.20.2-0.30.00.1-0.2-0.7-0.2-0.2-0.40.1-0.1-0.6-0.3-0.20.0-0.60.1-1.2-0.5
Bone: cortical tissue density1.41.94.2-0.9-0.8-0.8-0.80.80.5-0.9-1.5-1.91.6-1.90.1-1.9-1.8-2.0-1.7-1.90.20.91.01.5-1.9-1.6-0.8-2.0
Condit. Reinf. active minus inactive responses1.11.25.10.10.10.20.2-0.2-0.2-0.2-0.7-1.50.8-1.10.0-1.2-1.2-1.1-1.3-1.30.91.61.62.3-0.6-1.81.3-1.3
Condit. Reinf. active-inactive response ratio0.60.72.81.01.01.01.0-1.0-1.01.00.50.0-0.30.3-0.80.20.30.20.0-0.2-0.11.31.31.70.4-1.01.1-0.5
Condit. Reinf. active responses2.12.67.3-0.3-0.3-0.3-0.30.30.2-0.9-1.3-2.41.5-2.00.5-2.1-2.1-1.8-2.1-1.81.32.02.02.7-1.4-2.51.3-2.0
Condit. Reinf. inactive responses1.92.45.3-0.9-0.8-0.8-0.80.80.9-1.4-1.5-2.31.7-2.11.1-2.2-2.1-2.0-2.2-1.60.81.11.21.5-1.8-1.90.0-1.9
Incentive salience index mean1.51.95.0-0.6-0.6-0.6-0.50.50.5-1.0-1.3-2.21.4-1.80.7-1.8-1.8-1.6-1.8-1.81.61.31.21.8-1.1-1.71.5-1.3
Condit. Reinf. lever presses1.01.33.9-0.7-0.7-0.7-0.60.60.7-1.2-1.1-2.01.1-1.60.8-1.6-1.6-1.2-1.5-1.21.70.90.80.7-0.8-1.21.5-0.7
Condit. Reinf. active minus inactive responses1.31.75.51.41.61.51.6-1.6-1.71.00.90.0-0.70.1-1.80.10.20.40.50.5-0.92.32.32.10.1-2.20.6-1.4
Condit. Reinf. active-inactive response ratio1.11.34.21.11.31.21.3-1.3-1.30.90.6-0.0-0.40.0-1.50.00.10.20.30.2-0.92.02.02.0-0.1-1.90.3-1.4
Condit. Reinf. active responses1.82.57.61.82.01.92.0-2.0-2.01.41.20.2-0.90.3-2.10.40.40.60.60.6-0.92.82.72.30.4-2.41.1-1.4
Condit. Reinf. inactive responses0.91.23.11.31.31.31.3-1.3-1.41.10.90.2-0.70.5-1.50.50.50.70.60.3-0.01.81.61.10.8-1.21.7-0.4
Condit. Reinf. lever presses1.41.95.51.41.61.51.6-1.6-2.01.61.30.3-1.20.7-2.20.70.71.01.00.90.31.91.71.61.2-1.22.3-0.1
Condit. Reinf. lever reinforcers received1.62.27.41.61.91.71.8-1.8-1.91.21.1-0.1-0.80.1-2.00.20.30.50.50.5-0.52.72.72.10.4-2.41.4-1.3
Conditioned reinforcement - actives0.20.31.0-1.0-0.7-0.7-0.70.70.6-0.7-0.5-0.50.6-0.50.3-0.5-0.3-0.4-0.4-0.30.8-0.9-0.8-0.2-0.30.7-0.00.4
Conditioned reinforcement - inactives0.10.11.1-0.00.10.30.1-0.1-0.1-0.00.00.20.1-0.1-0.10.00.1-0.2-0.1-0.1-0.8-0.00.20.4-0.4-0.2-1.1-0.5
Conditioned locomotion0.50.63.0-0.6-0.4-0.3-0.40.40.4-0.2-0.00.0-0.10.30.60.30.30.60.20.31.5-1.1-1.1-0.80.91.41.61.7
Patch foraging indifference point 0 sec2.13.911.51.91.81.71.8-1.8-1.82.22.11.8-2.12.3-2.02.32.22.42.12.30.70.70.3-0.23.00.73.42.0
Patch foraging indifference point AUC1.62.34.0-1.7-1.5-1.8-1.51.51.8-1.5-1.7-2.01.9-1.71.8-1.9-1.6-1.8-2.0-1.91.5-0.6-0.5-0.1-1.5-0.1-0.4-0.6
Delay disc. indifference point, 0s delay0.60.63.6-0.1-0.1-0.1-0.10.10.00.30.20.1-0.30.60.10.40.60.70.60.31.4-0.8-1.1-0.71.21.41.91.7
Delay disc. indifference point, 16s delay1.11.26.4-0.4-0.4-0.5-0.40.40.30.30.30.8-0.50.80.20.80.80.60.70.40.7-2.0-2.2-1.91.02.50.52.0
Delay disc. indifference point, 2s delay0.60.71.31.11.11.21.1-1.1-0.70.90.90.7-0.90.9-0.60.80.80.70.60.4-0.80.91.00.20.6-0.60.4-0.2
Delay disc. indifference point, 24s delay1.11.32.7-1.3-1.3-1.5-1.31.31.3-1.1-1.0-0.80.8-0.71.1-0.6-0.6-0.6-0.7-0.91.6-1.6-1.6-1.2-0.21.40.51.1
Delay disc. indifference point, 4s delay1.11.23.40.30.40.40.4-0.4-0.20.70.91.3-1.11.3-0.11.31.41.41.30.90.0-1.2-1.3-1.61.41.80.61.9
Delay disc. indifference point, 8s delay3.64.38.41.21.21.21.2-1.2-1.42.12.12.6-2.32.7-1.52.72.72.62.72.1-0.1-1.4-1.7-1.82.82.81.52.9
Indifference point function ln k2.33.97.02.22.12.32.2-2.2-2.22.22.32.7-2.42.3-2.12.42.42.22.42.2-2.40.50.6-0.11.70.2-0.50.6
Indifference point function log k2.33.97.02.22.12.32.2-2.2-2.22.22.32.7-2.42.3-2.12.42.42.22.42.2-2.40.50.6-0.11.70.2-0.50.6
Patch foraging total patch changes 0 sec1.83.310.01.71.71.61.7-1.7-1.82.12.01.6-2.02.1-1.92.12.02.11.92.10.60.70.4-0.02.70.63.21.7
Patch foraging total patch changes 12 sec0.30.43.40.30.70.20.6-0.6-0.00.50.2-0.40.1-0.00.0-0.10.20.0-0.3-0.10.90.90.80.70.5-0.61.80.0
Patch foraging total patch changes 18 sec0.20.41.1-0.4-0.3-0.5-0.30.30.7-0.4-0.6-1.00.7-0.60.5-0.9-0.6-0.8-1.1-0.61.00.30.30.2-0.4-0.50.5-0.3
Patch foraging total patch changes 24 sec0.91.63.01.01.30.81.2-1.2-1.31.41.61.1-1.51.4-1.61.31.51.61.61.70.10.20.1-0.41.70.51.41.3
Patch foraging total patch changes 6 sec0.10.21.8-0.00.2-0.10.2-0.20.10.3-0.1-0.30.3-0.00.2-0.0-0.0-0.2-0.5-0.31.00.40.40.70.4-0.21.40.1
Patch foraging time to switch 0 sec0.30.52.3-0.5-0.3-0.3-0.30.30.2-0.6-0.6-1.10.6-0.90.2-0.8-0.9-0.6-0.7-0.61.40.70.60.9-0.2-0.91.5-0.3
Patch foraging water rate 0 sec0.51.13.21.41.31.21.3-1.3-1.31.51.00.9-0.80.8-1.30.70.80.50.60.5-1.81.11.20.80.2-0.8-0.7-0.9
Patch foraging water rate 12 sec0.30.65.70.20.00.10.1-0.1-0.40.1-0.10.30.2-0.3-0.4-0.2-0.2-0.6-0.2-0.3-1.80.20.30.8-1.1-0.5-2.4-1.4
Patch foraging water rate 18 sec0.30.51.80.40.20.40.2-0.2-0.60.60.61.3-0.70.8-0.50.90.80.50.90.6-1.3-0.6-0.6-0.20.20.8-1.30.2
Patch foraging water rate 24 sec0.91.25.01.00.80.90.9-0.9-1.41.10.30.3-0.20.1-1.30.00.1-0.5-0.2-0.1-1.91.41.52.2-0.7-1.4-1.3-1.9
Patch foraging water rate 6 sec1.11.65.1-0.7-0.8-0.6-0.80.80.4-0.8-1.3-0.91.4-1.40.2-1.3-1.4-1.8-1.4-1.4-1.10.50.61.4-2.0-1.2-2.3-2.2
Seeking ratio, delayed vs. immediate footshock0.91.04.00.81.11.11.1-1.1-0.50.60.40.00.2-0.3-0.5-0.20.2-0.10.0-0.4-1.71.62.01.3-0.6-2.0-0.9-1.7
Distance traveled before self-admin0.40.61.40.70.90.80.9-0.9-1.00.90.90.8-0.80.7-0.70.71.00.91.11.2-0.80.10.20.30.60.2-0.10.3
Distance traveled after self-admin0.20.21.50.20.40.30.3-0.3-0.60.3-0.0-0.10.1-0.3-0.3-0.1-0.2-0.20.1-0.1-0.60.80.71.2-0.3-0.8-0.3-0.8
Extensor digitorum longus weight0.31.12.61.00.90.80.9-0.9-1.21.31.31.5-1.61.4-0.61.41.41.11.11.4-0.9-0.2-0.2-0.41.10.7-0.10.6
Bone: elastic displacement0.10.20.6-0.3-0.1-0.1-0.20.20.50.1-0.00.10.10.30.40.30.20.1-0.00.10.7-0.4-0.5-0.70.50.60.80.7
Bone: elastic work0.60.82.01.01.01.01.0-1.0-0.91.40.90.8-0.81.0-1.01.00.90.80.70.8-0.00.70.60.51.1-0.11.30.4
Bone: endosteal estimation0.10.31.50.50.40.40.4-0.4-0.60.40.20.2-0.1-0.1-0.3-0.1-0.0-0.10.1-0.1-1.20.50.61.0-0.5-0.7-1.2-0.9
Bone: endosteal perimeter0.10.21.40.40.30.30.3-0.3-0.40.3-0.10.00.0-0.1-0.3-0.1-0.1-0.1-0.0-0.2-0.60.50.51.2-0.2-0.5-0.5-0.6
Epididymis fat weight0.41.53.30.90.80.80.7-0.7-0.40.91.31.7-1.41.8-0.21.61.61.51.41.7-0.7-0.7-0.8-1.81.41.30.31.4
Delta time in closed arm before/after self-admin0.30.31.00.30.40.40.3-0.30.0-0.10.0-0.10.2-0.20.1-0.3-0.2-0.4-0.5-0.4-0.90.60.80.4-0.6-0.9-0.9-1.0
Delta time in open arm before/after self-admin1.31.24.61.21.21.31.4-1.4-1.21.20.80.9-0.70.4-1.20.60.70.30.50.4-2.11.21.31.2-0.3-1.3-1.5-1.4
Diff in mean of infusions in LGA sessions0.20.30.8-0.00.1-0.00.2-0.20.1-0.0-0.3-0.70.5-0.50.1-0.6-0.4-0.5-0.6-0.50.60.80.90.8-0.3-0.90.8-0.6
Delay discount exponential model param1.71.96.0-0.4-0.5-0.5-0.50.50.4-1.0-1.2-1.61.4-1.70.4-1.7-1.7-1.7-1.7-1.1-0.11.61.72.0-1.8-2.4-0.8-2.4
Extinction: sum of active levers before priming0.91.01.9-1.4-1.3-1.2-1.21.21.4-1.0-1.1-0.71.1-0.61.3-0.6-0.7-0.8-0.8-0.81.2-1.2-1.2-0.8-0.51.0-0.00.5
Active lever presses in extinction session 60.60.62.1-0.8-0.6-0.8-0.70.71.1-0.5-0.4-0.10.4-0.11.3-0.1-0.1-0.1-0.2-0.30.7-1.3-1.3-1.5-0.01.2-0.10.9
Bone: final force1.01.73.21.81.71.71.7-1.7-1.71.61.20.9-1.20.8-1.20.80.80.60.50.7-1.61.71.71.60.5-1.3-0.1-1.0
Bone: final moment0.91.42.81.71.51.51.5-1.5-1.51.51.00.8-1.10.7-1.00.70.80.50.40.6-1.51.61.61.60.4-1.2-0.1-1.0
Food consumed during 24 hour testing period0.20.22.0-0.4-0.4-0.4-0.40.40.2-0.5-0.3-0.10.1-0.30.2-0.3-0.4-0.4-0.2-0.0-0.8-0.3-0.3-0.2-0.7-0.0-1.4-0.5
Glucose1.01.55.11.61.71.61.6-1.6-0.81.61.41.6-1.31.4-0.41.41.40.80.60.7-2.30.81.0-0.10.5-0.5-1.0-0.6
Heart weight3.96.19.33.03.02.93.0-3.0-2.92.73.02.8-3.02.7-2.72.72.82.72.72.9-2.51.41.50.22.1-0.50.00.4
Delay discount hyperbolic model param1.61.74.3-0.6-0.7-0.6-0.70.70.5-1.1-1.2-1.61.4-1.70.5-1.7-1.7-1.7-1.7-1.10.11.21.31.7-1.7-2.1-0.8-2.1
Intermittent access intake day 1-15 change0.40.75.60.40.30.50.3-0.3-1.10.40.30.7-0.30.2-1.50.20.1-0.10.30.6-1.90.30.31.3-0.7-0.5-2.4-1.1
Intermittent access intake escalation0.40.84.40.60.50.70.5-0.5-1.30.60.50.8-0.50.4-1.70.40.30.10.60.7-1.90.40.41.3-0.4-0.5-2.1-1.0
Intermittent access intake escalation 20.70.810.4-0.6-0.7-0.5-0.70.7-0.0-0.5-0.40.30.3-0.3-0.5-0.3-0.3-0.6-0.20.1-1.6-1.0-0.90.1-1.30.4-3.2-0.7
Intermitt. access day 1 inactive lever presses0.51.93.61.81.51.71.5-1.5-1.61.11.61.4-1.81.5-1.11.61.31.91.71.6-0.71.00.9-0.11.7-0.31.20.8
Intermitt. access day 15 inactive lever presses0.40.91.81.21.31.31.3-1.3-1.01.01.00.9-0.90.7-0.90.80.80.70.50.7-1.41.01.10.70.4-0.9-0.2-0.5
Intermitt. access escalation Index0.81.14.21.11.01.01.0-1.0-1.40.90.5-0.1-0.40.1-1.20.10.00.00.00.4-0.52.01.92.10.1-1.80.8-1.2
Intermittent access day 1 total infusions0.20.21.1-0.6-0.3-0.4-0.30.30.5-0.1-0.3-0.30.4-0.10.5-0.10.0-0.1-0.3-0.51.1-0.6-0.6-0.10.30.71.00.8
Intermittent access day 15 total infusions0.30.41.40.50.70.60.7-0.7-0.90.70.50.6-0.40.4-1.20.40.50.20.30.4-0.90.40.51.20.1-0.3-0.6-0.4
Intermittent access terminal intake (last 3 days)0.20.32.30.00.30.30.3-0.3-0.70.40.20.5-0.10.2-1.00.20.3-0.10.10.3-1.2-0.10.01.0-0.4-0.0-1.5-0.6
Intermittent access total infusions0.10.10.40.00.30.20.3-0.3-0.50.50.30.3-0.10.2-0.60.30.40.20.10.1-0.3-0.10.00.60.10.1-0.10.1
Intermittent access day 1 locomotion0.91.23.80.40.60.60.6-0.6-0.40.91.01.1-0.91.2-0.21.31.41.41.11.10.7-0.7-0.8-0.71.81.41.71.9
Intermittent access day 15 total locomotion0.30.52.10.60.80.80.8-0.8-0.80.80.71.0-0.60.7-0.60.70.80.60.70.6-1.50.10.30.50.2-0.1-1.1-0.2
Intermittent access total locomotion0.20.20.7-0.10.20.20.2-0.2-0.30.40.40.6-0.30.5-0.20.60.70.60.60.6-0.0-0.6-0.6-0.10.60.80.10.9
Intermittent access standard deviation0.20.32.80.20.20.40.2-0.2-0.70.20.30.6-0.40.3-0.90.30.1-0.10.00.5-1.40.00.10.7-0.4-0.2-1.7-0.7
Left kidney weight2.612.121.84.03.83.93.9-3.9-2.63.54.24.7-4.34.6-2.04.54.44.33.93.9-3.50.80.8-1.93.70.70.41.9
Right kidney weight3.817.429.84.74.54.54.5-4.5-3.34.15.15.4-5.25.5-2.95.35.35.45.05.0-3.40.80.7-2.24.71.11.12.7
Cocaine induced anxiety1.11.53.31.21.21.21.2-1.2-0.60.81.51.4-1.51.5-0.21.51.61.81.31.7-0.20.0-0.0-0.81.80.61.41.5
Post-drug Anxiety1.61.73.01.71.71.71.7-1.7-0.80.91.71.5-1.61.5-0.21.51.51.71.21.6-1.20.80.9-0.61.4-0.40.60.6
Baseline Anxiety0.20.21.10.40.30.40.3-0.3-0.1-0.00.0-0.10.0-0.2-0.1-0.2-0.3-0.3-0.3-0.3-0.80.80.90.2-0.5-1.0-0.7-1.1
Tail length1.97.313.73.43.43.43.4-3.4-3.12.83.23.0-3.12.8-2.82.72.82.72.82.5-3.72.02.20.51.7-1.3-0.7-0.4
Length with tail1.46.09.63.13.03.13.0-3.0-2.92.72.92.6-2.92.5-2.62.62.52.62.62.4-2.61.91.90.62.1-1.00.40.0
Length without tail0.61.83.41.51.41.51.4-1.4-1.61.61.61.6-1.81.4-1.41.61.51.51.61.7-1.30.70.6-0.11.3-0.00.30.3
Times rat made contact with spout0.40.51.00.60.60.60.6-0.6-0.70.80.70.8-0.90.9-0.40.90.80.80.70.7-0.1-0.0-0.10.11.00.50.70.7
Lifetime Intake0.10.10.4-0.4-0.1-0.2-0.10.1-0.20.30.00.20.10.1-0.40.20.30.10.1-0.00.2-0.5-0.50.40.20.70.20.5
Liver weight, left3.76.113.93.02.82.92.8-2.8-3.42.62.72.3-2.72.4-3.72.32.22.62.92.7-2.12.21.91.22.0-1.10.90.0
Liver weight, right2.33.96.32.12.02.22.1-2.1-2.32.52.42.3-2.52.4-2.42.42.42.32.42.2-1.20.80.6-0.12.20.31.11.0
Locomotor activity0.20.30.7-0.8-0.7-0.7-0.70.70.7-0.8-0.5-0.30.4-0.50.7-0.3-0.2-0.1-0.1-0.00.7-0.7-0.8-0.7-0.00.70.40.6
Locomotor testing distance0.30.61.4-1.1-0.9-0.9-0.80.81.1-0.8-0.7-0.60.8-0.81.2-0.6-0.4-0.5-0.7-0.41.0-0.9-0.8-0.7-0.20.70.40.5
Locomotor testing rearing0.71.53.1-1.5-1.2-1.2-1.11.11.5-1.5-1.3-1.51.5-1.71.8-1.5-1.4-1.5-1.6-1.10.9-0.3-0.0-0.2-1.3-0.5-0.3-0.7
Locomotion in novel chamber0.30.30.90.50.70.70.7-0.7-0.50.90.60.7-0.40.6-0.60.80.80.60.60.20.10.30.40.20.80.00.70.3
Locomotion in novel chamber post-restriction0.91.54.11.41.41.41.3-1.3-1.71.31.21.1-1.20.9-2.00.91.01.11.60.9-1.61.21.20.70.5-0.8-0.6-0.5
Fecal boli incidents, locomotor time 10.71.02.8-1.4-1.4-1.3-1.31.31.0-0.9-1.1-0.70.9-0.70.7-0.6-0.7-0.7-0.7-0.61.2-1.5-1.7-0.6-0.41.4-0.10.8
Change in fecal boli incidents, locomotor task2.22.23.71.91.91.91.9-1.9-1.51.71.91.6-1.71.5-1.31.51.61.41.41.5-1.91.21.4-0.00.9-0.9-0.3-0.3
Time >=10cm from walls, locomotor time 10.20.20.9-0.1-0.2-0.2-0.30.30.0-0.3-0.3-0.30.4-0.4-0.1-0.4-0.6-0.6-0.5-0.2-0.60.40.40.5-0.8-0.7-0.9-1.0
Bouts of movement, locomotor time 13.43.96.5-2.5-2.5-2.4-2.62.61.9-2.3-2.4-2.02.2-2.01.8-2.0-2.1-1.9-1.7-1.92.1-1.9-1.90.1-1.51.2-0.40.3
Total resting periods, locomotor time 13.33.75.7-2.3-2.4-2.3-2.42.41.9-2.2-2.4-2.22.2-2.11.8-2.1-2.1-2.0-1.9-1.92.1-1.4-1.40.2-1.60.7-0.3-0.1
Rest time, locomotor task time 10.10.10.30.10.1-0.10.0-0.0-0.1-0.1-0.1-0.40.1-0.30.1-0.3-0.3-0.3-0.3-0.00.30.50.50.5-0.2-0.60.3-0.4
Distance moved, locomotor task time 10.10.10.3-0.4-0.2-0.3-0.30.30.3-0.1-0.3-0.50.5-0.30.0-0.4-0.4-0.4-0.5-0.50.40.10.00.1-0.1-0.10.4-0.1
Vertical activity count, locomotor time 10.10.21.10.20.40.40.3-0.3-0.60.30.10.00.10.0-1.0-0.0-0.10.10.3-0.1-0.60.80.81.1-0.1-0.8-0.1-0.7
Time >=10cm from walls, locomotor time 26.59.514.23.73.63.83.6-3.6-3.73.43.53.1-3.43.2-3.63.23.23.53.63.2-2.32.52.31.23.0-1.21.70.5
Bouts of movement, locomotor time 20.30.42.70.50.20.40.2-0.2-1.20.50.1-0.0-0.1-0.0-1.40.1-0.10.00.50.4-0.01.00.81.70.0-0.80.2-0.6
Total resting periods, locomotor time 20.20.43.20.40.10.20.2-0.2-1.10.5-0.0-0.20.1-0.1-1.4-0.1-0.2-0.10.40.20.01.00.81.8-0.1-0.90.2-0.8
Rest time, locomotor task time 23.64.67.7-2.4-2.3-2.6-2.32.32.7-2.5-2.5-2.32.5-2.42.8-2.3-2.3-2.4-2.6-2.21.7-1.3-1.1-0.5-2.20.3-1.0-0.6
Distance moved, locomotor task time 21.61.93.11.71.71.81.6-1.6-1.41.61.61.4-1.61.6-1.41.51.51.61.51.2-0.81.10.90.01.6-0.31.40.5
Vertical activity count, locomotor time 23.04.17.92.52.42.62.3-2.3-2.62.32.01.8-2.01.8-2.81.81.61.82.01.5-1.82.42.31.51.5-1.60.9-0.6
Light reinforcement 11.23.014.62.02.12.02.1-2.1-1.71.81.40.5-1.00.9-1.61.01.11.30.90.70.92.52.22.02.0-1.53.80.2
Light reinforcement 20.60.92.4-0.7-0.5-0.7-0.50.50.9-0.8-1.0-1.41.3-1.20.8-1.3-1.0-1.0-1.1-1.61.20.30.40.9-0.7-0.70.6-0.6
Bone: marrow area0.10.31.50.60.50.40.5-0.5-0.70.50.30.3-0.20.0-0.40.10.1-0.00.20.1-1.20.50.60.9-0.4-0.6-1.1-0.8
Bone: maximum diameter0.91.84.01.71.61.61.6-1.6-2.01.61.31.1-1.31.1-1.81.01.21.11.21.2-1.21.31.21.70.9-0.80.4-0.3
Bone: maximum force1.83.15.72.42.32.32.2-2.2-2.12.12.01.7-2.11.8-1.61.71.71.71.51.7-1.71.51.60.91.5-0.80.6-0.0
Bone: maximum moment1.42.54.72.22.02.02.0-2.0-1.92.01.81.6-1.91.6-1.41.61.61.51.41.6-1.51.31.40.81.4-0.70.50.0
Mean time between licks in bursts0.51.22.9-1.4-1.5-1.4-1.51.51.3-1.4-1.0-0.60.7-0.51.4-0.7-0.7-0.6-0.6-0.30.5-1.7-1.7-1.2-0.61.2-0.90.7
Mean num. licks in bursts0.60.92.31.11.11.11.1-1.1-0.90.91.10.8-1.11.0-0.51.01.01.20.91.10.00.70.60.21.4-0.11.50.7
Cd content in liver0.30.30.90.70.50.60.5-0.5-0.80.70.60.5-0.70.6-0.90.50.40.50.60.3-0.40.50.5-0.10.4-0.20.2-0.1
Co content in liver0.50.52.4-0.4-0.4-0.5-0.50.50.10.20.20.8-0.40.70.20.60.60.40.60.50.2-1.4-1.4-1.20.51.5-0.31.1
Cu content in liver0.60.72.8-0.6-0.7-0.7-0.70.70.9-0.9-0.9-0.71.0-0.80.7-0.9-0.9-1.0-1.0-1.1-0.6-0.2-0.10.0-1.3-0.4-1.7-1.0
Fe content in liver2.53.06.7-0.7-0.9-0.9-0.90.90.2-1.3-1.7-2.51.6-2.40.3-2.4-2.5-2.2-2.2-2.20.61.51.42.6-2.0-2.1-0.2-2.3
K content in liver0.20.21.10.20.30.30.2-0.2-0.60.10.40.5-0.50.4-0.80.30.30.30.70.7-0.9-0.2-0.1-0.1-0.10.1-1.1-0.0
Mg content in liver0.70.73.10.60.70.70.6-0.6-1.20.90.70.9-0.70.6-1.30.60.60.30.70.8-1.70.20.30.7-0.2-0.2-1.7-0.6
Mn content in liver1.61.82.81.41.61.61.6-1.6-1.51.61.61.6-1.51.5-1.21.61.71.61.51.5-1.00.60.60.31.40.00.50.6
Na content in liver0.50.51.5-0.8-0.8-0.8-0.90.90.4-1.2-0.8-1.00.6-1.10.4-1.1-1.1-0.8-0.6-0.40.3-0.2-0.20.0-1.0-0.3-0.7-0.5
Rb content in liver3.03.46.91.91.91.91.9-1.9-1.82.22.32.6-2.42.5-1.32.42.42.12.12.2-1.80.10.1-0.51.80.7-0.20.9
Se content in liver0.10.10.40.20.30.30.2-0.20.00.30.10.2-0.00.20.20.10.1-0.1-0.2-0.1-0.70.30.40.1-0.1-0.3-0.6-0.4
Sr content in liver0.30.20.7-0.5-0.6-0.6-0.60.60.5-0.5-0.2-0.00.00.00.20.1-0.10.10.10.20.5-0.8-0.8-0.80.20.70.20.8
Zn content in liver1.31.53.6-0.7-0.6-0.6-0.70.70.3-1.1-1.2-1.31.3-1.5-0.0-1.6-1.6-1.5-1.1-1.2-0.60.50.71.5-1.9-1.3-1.8-1.9
Bone: minimum diameter1.42.64.71.41.21.21.2-1.2-1.31.61.72.1-2.12.1-1.12.12.12.22.22.1-0.5-0.5-0.6-1.12.11.30.81.8
Time in familiar zone, hab. session 11.41.42.3-1.4-1.5-1.5-1.51.51.0-1.4-1.4-1.31.4-1.30.6-1.3-1.3-1.2-0.9-1.20.8-0.9-0.9-0.2-1.30.3-0.9-0.3
Time in novel zone, hab. session 12.12.13.71.81.91.91.9-1.9-1.51.81.61.4-1.51.5-1.01.51.51.31.01.3-1.11.41.41.01.4-0.71.00.0
Total zone transitions, hab. session 10.50.71.6-1.2-1.0-1.1-1.01.00.8-1.1-0.6-0.70.5-0.70.6-0.6-0.5-0.3-0.1-0.31.1-1.0-1.1-1.3-0.30.80.00.6
Total locomotion distance, hab. session 10.50.62.4-1.1-0.9-0.9-0.90.91.0-1.0-0.5-0.40.4-0.40.8-0.4-0.3-0.00.0-0.21.1-1.1-1.1-1.5-0.00.90.31.0
Locomotion velocity, hab. session 10.71.03.3-1.4-1.1-1.2-1.11.11.2-1.3-0.7-0.70.5-0.61.0-0.6-0.5-0.1-0.1-0.31.5-1.3-1.3-1.8-0.11.10.51.1
Time in familiar zone, hab. session 20.10.10.90.0-0.0-0.00.0-0.0-0.70.3-0.0-0.30.0-0.2-0.9-0.2-0.1-0.20.1-0.10.10.30.30.9-0.1-0.30.1-0.3
Time in novel zone, hab. session 20.50.51.00.70.80.80.7-0.70.00.50.71.0-0.71.00.41.00.90.90.50.7-0.60.00.0-0.70.80.30.30.6
Total zone transitions, hab. session 20.40.52.3-0.9-0.8-0.8-0.80.80.7-0.9-0.3-0.10.1-0.20.7-0.2-0.20.00.10.00.3-1.3-1.2-1.5-0.21.1-0.70.8
Total locomotion distance, hab. session 20.00.10.4-0.1-0.1-0.0-0.00.00.2-0.30.10.1-0.10.10.20.10.10.30.20.10.2-0.3-0.3-0.70.10.20.10.4
Locomotion velocity, hab. session 20.10.10.5-0.3-0.3-0.3-0.20.20.3-0.5-0.1-0.20.0-0.10.3-0.1-0.10.20.10.00.5-0.4-0.4-0.70.10.30.30.5
Novel to familiar place preference ratio1.51.72.91.71.71.61.7-1.7-1.51.61.31.0-1.01.2-1.41.21.31.41.20.8-0.51.31.31.21.4-0.71.40.2
Novelty place preference1.41.52.71.61.61.61.6-1.6-1.41.51.21.0-1.01.2-1.31.21.31.41.20.8-0.51.21.21.01.4-0.61.40.3
Time in novel zone, NPP test1.41.52.61.61.61.61.6-1.6-1.31.51.21.0-0.91.1-1.21.11.21.31.10.6-0.61.31.21.11.3-0.71.30.2
Total zone transitions, NPP test1.31.95.2-1.7-1.6-1.6-1.71.71.7-1.7-1.0-0.40.6-0.71.7-0.7-0.7-0.7-0.6-0.40.4-2.2-2.0-2.3-1.01.5-1.70.7
Total locomotion distance, NPP test0.81.16.9-0.8-0.8-0.8-0.80.81.3-0.9-0.20.4-0.10.31.50.30.20.30.10.10.1-1.9-1.8-2.60.01.7-0.91.3
Locomotion velocity, NPP test1.01.37.9-1.0-1.0-0.9-0.90.91.4-1.0-0.20.4-0.10.31.60.30.20.30.10.20.3-2.2-2.0-2.80.11.9-0.91.5
Intraocular pressure1.01.43.7-1.5-1.5-1.5-1.61.61.1-0.9-1.4-1.21.4-1.00.9-1.0-1.2-1.1-1.1-0.91.9-0.9-1.10.3-0.40.80.70.4
Delta distance traveled before/after self-admin0.20.20.6-0.3-0.5-0.4-0.50.50.2-0.5-0.6-0.60.5-0.60.1-0.4-0.8-0.6-0.6-0.70.50.40.20.5-0.3-0.50.4-0.4
Delta ambulatory time before/after self-admin0.40.51.1-0.4-0.5-0.5-0.60.60.5-0.7-0.8-1.00.8-1.00.5-0.7-1.0-0.7-0.8-1.00.90.50.40.6-0.4-0.70.8-0.5
Parametrial fat weight0.10.32.00.50.40.50.5-0.5-0.40.10.60.2-0.70.4-0.10.40.50.70.40.70.50.20.2-0.10.90.01.40.7
Pavlov. Cond. lever latency0.30.31.90.60.50.50.4-0.4-1.00.80.30.4-0.20.3-0.90.30.2-0.10.10.3-1.00.50.51.4-0.1-0.4-0.7-0.7
Pavlov. Cond. magazine entry latency0.60.84.71.11.11.11.1-1.1-0.30.50.5-0.2-0.20.0-0.20.20.20.50.1-0.30.51.61.50.60.8-1.32.2-0.2
Pavlov. Cond. change in total contacts0.20.21.10.50.50.50.5-0.50.3-0.20.0-0.10.2-0.20.6-0.2-0.2-0.1-0.3-0.6-0.70.80.90.1-0.3-1.0-0.3-0.7
Pavlov. Cond. index score0.20.32.1-0.1-0.1-0.1-0.00.00.7-0.5-0.3-0.70.4-0.40.5-0.4-0.3-0.0-0.3-0.71.10.30.3-0.50.2-0.31.40.3
Pavlov. Cond. latency score0.20.33.0-0.1-0.0-0.10.0-0.00.5-0.4-0.1-0.50.1-0.20.3-0.1-0.10.30.0-0.31.30.20.1-0.70.5-0.11.70.6
Pavlov. Cond. lever contacts0.30.31.5-0.5-0.4-0.4-0.30.31.0-0.8-0.4-0.60.3-0.40.8-0.4-0.3-0.1-0.3-0.51.0-0.2-0.2-1.20.00.10.90.5
Pavlov. Cond. magazine entry number0.50.73.4-1.1-1.1-1.1-1.21.20.3-0.6-0.6-0.10.4-0.30.2-0.4-0.5-0.6-0.20.3-0.3-1.3-1.3-0.3-0.90.9-1.80.0
Pavlov. Cond. intertrial magazine entries0.70.82.9-0.4-0.4-0.4-0.40.4-0.5-0.1-0.6-0.80.5-1.0-0.8-1.0-1.0-1.3-0.9-0.2-0.70.50.61.3-1.4-0.9-1.6-1.7
Pavlov. Cond. lever-magazine prob. diff.0.30.31.1-0.3-0.3-0.3-0.20.21.0-0.7-0.5-0.70.6-0.50.9-0.5-0.4-0.2-0.5-0.91.00.10.0-0.7-0.0-0.21.00.2
Pavlov. Cond. response bias0.30.41.30.10.20.10.2-0.20.7-0.4-0.4-0.70.6-0.70.8-0.5-0.5-0.4-0.8-1.10.40.80.90.0-0.3-1.00.8-0.5
Pavlov. Cond. lever latency3.14.27.1-2.5-2.6-2.5-2.62.62.7-2.5-2.1-1.22.0-1.52.6-1.5-1.6-1.6-1.5-1.50.7-2.5-2.4-2.0-1.81.5-2.20.3
Pavlov. Cond. magazine entry latency1.82.27.31.81.81.81.8-1.8-1.71.41.0-0.0-0.80.3-1.60.30.30.30.10.2-0.52.72.62.40.5-2.31.6-1.3
Pavlov. Cond. change in total contacts1.52.58.11.81.91.81.9-1.9-1.81.31.1-0.1-0.80.2-1.80.20.20.30.20.2-0.82.82.82.60.3-2.61.2-1.5
Pavlov. Cond. index score2.83.710.52.42.42.32.4-2.4-2.42.01.50.4-1.20.6-2.40.60.60.70.50.5-1.03.23.22.90.8-2.71.6-1.5
Pavlov. Cond. latency score2.33.08.62.22.22.12.2-2.2-2.11.71.30.3-1.10.5-2.00.50.60.60.40.4-1.02.92.92.60.6-2.51.4-1.4
Pavlov. Cond. lever contacts3.44.89.02.62.82.62.7-2.7-2.92.62.21.1-2.01.5-3.01.51.51.71.51.5-0.72.82.62.31.8-1.82.5-0.4
Pavlov. Cond. magazine entry number2.02.58.1-2.0-1.9-1.9-1.91.91.8-1.4-1.1-0.10.9-0.31.7-0.3-0.3-0.3-0.1-0.21.0-2.8-2.8-2.4-0.42.5-1.11.6
Pavlov. Cond. intertrial magazine entries0.71.04.1-0.4-0.3-0.3-0.30.30.30.20.41.1-0.51.00.31.01.00.91.00.90.1-1.7-1.8-2.00.92.0-0.21.7
Pavlov. Cond. lever-magazine prob. diff.2.63.49.82.32.32.32.3-2.3-2.31.91.40.3-1.20.6-2.20.60.60.70.50.5-1.03.13.12.80.8-2.61.6-1.4
Pavlov. Cond. response bias4.25.712.42.93.02.93.0-3.0-3.22.72.20.9-1.91.3-3.21.31.31.41.31.3-1.03.53.43.11.6-2.62.4-1.1
Time in closed arm before self-admin1.72.23.9-1.7-1.9-1.8-1.81.81.1-1.6-1.8-2.01.6-1.81.1-1.8-1.9-1.7-1.5-1.41.8-0.4-0.50.5-1.3-0.10.3-0.5
Time in closed arm after self-admin1.31.43.1-0.8-1.0-0.9-0.90.90.7-1.2-1.2-1.71.2-1.60.6-1.6-1.6-1.6-1.6-1.30.70.60.71.0-1.3-1.2-0.0-1.3
Time in open arm before self-admin0.60.71.50.70.80.50.7-0.7-0.61.10.91.0-0.81.2-0.61.21.11.00.80.90.0-0.1-0.2-0.41.20.80.91.0
Time in open arm after self-admin1.71.85.11.41.61.61.6-1.6-1.41.81.41.9-1.21.4-1.31.61.61.11.21.0-2.30.50.70.40.5-0.2-1.4-0.4
Bone: periosteal estimation0.61.22.21.51.31.31.3-1.3-1.51.51.21.2-1.31.1-1.21.11.21.01.21.1-1.30.70.70.90.8-0.3-0.2-0.1
Bone: periosteal perimeter0.81.42.41.41.31.31.3-1.3-1.21.41.31.5-1.41.5-1.11.51.61.51.41.4-0.80.20.20.21.40.40.50.8
Bone: post-yield work0.10.21.5-0.1-0.3-0.3-0.20.20.5-0.7-0.10.1-0.1-0.10.9-0.1-0.10.0-0.1-0.1-0.6-0.6-0.5-0.8-0.40.3-1.20.0
Progressive ratio test 1 active lever presses0.10.10.8-0.4-0.1-0.2-0.10.1-0.1-0.0-0.3-0.40.4-0.4-0.2-0.3-0.2-0.2-0.3-0.40.50.10.10.9-0.1-0.10.5-0.0
Progressive ratio test 1 breakpoint0.10.10.6-0.4-0.2-0.2-0.20.2-0.0-0.1-0.3-0.40.4-0.4-0.1-0.3-0.2-0.2-0.3-0.40.5-0.00.10.8-0.1-0.10.40.0
Progressive ratio test 1 inactive lever presses0.10.10.80.10.20.20.2-0.2-0.1-0.1-0.1-0.30.2-0.30.0-0.2-0.2-0.2-0.4-0.30.10.50.60.9-0.1-0.60.4-0.3
Progressive ratio test 2 active lever presses0.20.32.2-0.10.40.20.4-0.4-0.40.5-0.0-0.40.3-0.4-0.5-0.4-0.0-0.4-0.4-0.50.00.70.81.5-0.4-0.80.2-0.7
Progressive ratio test 2 breakpoint0.30.32.40.10.60.40.6-0.6-0.70.60.2-0.30.2-0.3-0.7-0.30.1-0.2-0.3-0.3-0.10.80.91.6-0.3-0.90.3-0.7
Progressive ratio test 2 inactive lever presses0.20.30.80.40.80.60.8-0.8-0.60.70.50.3-0.20.2-0.50.20.60.2-0.00.1-0.50.50.70.90.1-0.40.0-0.3
Incentive Sensitization - Responses0.00.10.5-0.10.30.00.3-0.3-0.30.50.1-0.10.1-0.1-0.4-0.10.3-0.2-0.2-0.1-0.10.00.10.7-0.2-0.0-0.1-0.2
Incentive Sensitization - Breakpoint0.10.10.7-0.00.30.10.3-0.3-0.40.50.1-0.10.1-0.1-0.5-0.10.3-0.2-0.1-0.1-0.10.20.20.9-0.1-0.20.1-0.3
Sum of active levers in priming session hrs 5-60.40.42.3-0.5-0.4-0.4-0.40.40.7-0.6-0.5-0.20.6-0.60.8-0.4-0.5-0.7-0.6-0.8-0.5-0.2-0.0-0.3-1.0-0.3-1.5-0.7
Progressive ratio0.10.10.40.1-0.3-0.2-0.30.3-0.2-0.3-0.3-0.60.3-0.4-0.4-0.6-0.4-0.30.1-0.0-0.10.50.40.5-0.4-0.7-0.1-0.5
Food seeking constrained by brief footshock0.00.10.3-0.2-0.3-0.3-0.20.20.3-0.2-0.1-0.10.1-0.00.3-0.1-0.00.10.1-0.20.3-0.2-0.2-0.50.20.20.30.4
Seeking ratio, punishment vs. effort0.10.10.3-0.3-0.0-0.1-0.00.00.40.1-0.10.00.1-0.00.60.10.0-0.0-0.3-0.30.5-0.3-0.2-0.30.20.40.40.4
Retroperitoneal fat weight3.012.920.04.54.34.44.4-4.4-4.44.24.13.2-4.03.6-3.93.63.63.83.63.8-2.03.13.01.73.7-1.43.00.7
Reaction time number correct1.73.28.22.42.02.11.9-1.9-2.22.02.02.1-2.01.9-2.11.81.61.51.71.9-2.91.31.30.70.9-0.7-1.0-0.6
Reaction time mean minus median0.41.12.00.81.31.31.3-1.3-1.11.41.11.0-0.90.8-1.41.11.21.21.31.0-0.50.70.70.21.1-0.20.80.3
Reaction time mean minus median AUC1.33.25.51.82.32.22.3-2.3-1.92.32.11.9-1.91.6-2.02.02.12.02.11.8-1.21.11.10.31.8-0.31.10.6
Reaction time num false alarms0.10.11.10.2-0.00.1-0.00.00.5-0.20.20.1-0.30.20.80.10.00.2-0.20.30.1-0.1-0.1-1.10.20.10.30.3
Reaction time num false alarms AUC0.10.10.60.1-0.1-0.1-0.10.10.5-0.4-0.1-0.30.1-0.20.8-0.3-0.3-0.2-0.5-0.00.10.20.2-0.4-0.2-0.40.1-0.3
Reaction time trials correct on left1.73.28.22.42.02.11.9-1.9-2.22.02.02.1-2.01.9-2.11.81.61.51.71.9-2.91.31.30.70.9-0.7-1.0-0.6
Reaction time trials on left1.73.28.02.42.02.12.0-2.0-2.22.02.02.1-2.01.9-2.11.81.61.51.71.9-2.81.31.30.80.9-0.8-0.9-0.6
Reaction time mean0.60.91.7-0.5-0.4-0.4-0.40.40.3-0.4-1.0-1.31.2-1.3-0.1-1.2-1.2-1.2-1.0-1.30.60.90.91.3-1.0-1.30.0-1.3
Reaction time mean AUC0.30.41.2-0.3-0.1-0.1-0.10.1-0.1-0.0-0.6-0.80.7-0.9-0.3-0.7-0.7-0.7-0.5-0.80.40.80.81.1-0.6-1.00.2-1.0
Median of all reaction times1.62.34.6-1.2-1.3-1.3-1.21.21.0-1.2-1.9-2.12.0-2.00.7-2.0-2.0-2.0-1.9-2.21.10.60.71.3-1.7-1.3-0.3-1.6
Reaction time omissions0.71.02.21.11.21.31.2-1.2-0.91.11.00.9-0.91.0-0.81.10.91.21.00.9-0.10.90.80.31.3-0.31.50.5
Reaction time false alarm rate0.60.92.3-0.9-0.9-1.0-0.90.91.3-1.1-0.9-1.20.9-0.91.5-1.0-0.9-0.8-1.1-0.91.4-0.4-0.4-0.8-0.40.10.70.2
Reaction time premature initiation rate0.91.23.4-0.6-0.6-0.7-0.60.60.5-1.2-1.0-1.81.2-1.50.5-1.5-1.5-1.1-1.2-1.01.31.00.91.3-0.9-1.41.2-0.9
Reaction time premature initiations0.40.73.20.60.50.40.4-0.4-0.6-0.20.0-0.70.1-0.5-0.6-0.5-0.7-0.3-0.3-0.0-0.31.71.61.6-0.4-1.80.6-1.2
Std. dev. reaction times0.61.12.40.91.31.31.3-1.3-1.31.51.00.8-0.80.7-1.51.01.01.01.10.7-0.31.11.00.81.1-0.51.10.1
Reaction time trials completed1.73.28.02.42.02.12.0-2.0-2.22.02.02.1-2.01.9-2.11.81.61.51.71.9-2.81.31.30.80.9-0.8-0.9-0.6
Reaction time trials AUC1.73.28.42.42.02.12.0-2.0-2.31.91.91.9-1.91.7-2.21.61.31.31.51.7-2.91.61.61.20.7-1.1-1.0-1.0
Run reversals in cocaine runway, females0.20.23.10.20.10.20.1-0.10.2-0.20.00.5-0.00.10.30.10.10.00.20.0-1.3-0.2-0.0-0.4-0.5-0.1-1.8-0.5
Run reversals in cocaine runway, males1.11.12.1-1.2-1.5-1.5-1.21.21.1-1.2-1.3-1.01.1-1.11.0-1.1-1.1-1.2-1.3-0.80.6-0.9-0.8-0.1-1.10.3-0.8-0.2
Latency to leave start box in cocaine runway0.20.31.30.2-0.1-0.0-0.10.1-0.4-0.2-0.3-0.70.2-0.5-0.5-0.6-0.6-0.3-0.2-0.20.30.80.81.1-0.4-1.00.3-0.7
Latency to leave start box in cocaine runway, F0.30.40.9-0.8-0.9-0.8-0.90.90.5-0.7-0.7-0.70.5-0.60.4-0.7-0.6-0.4-0.3-0.30.9-0.7-0.7-0.2-0.40.5-0.00.3
Latency to leave start box in cocaine runway, M2.11.97.11.61.41.41.4-1.4-1.60.80.6-0.2-0.3-0.1-1.5-0.1-0.10.00.0-0.0-1.02.72.72.6-0.1-2.70.4-1.8
Std. dev. time between licks in bursts1.31.73.50.91.01.01.0-1.0-1.01.31.51.7-1.51.7-1.11.71.71.71.71.9-0.4-0.4-0.5-1.21.71.20.81.5
Total sessions with >9 infusions0.70.83.3-1.1-0.9-0.9-0.90.90.5-0.3-0.6-0.30.5-0.10.4-0.1-0.10.10.1-0.31.8-1.3-1.5-0.40.61.61.41.5
Short access day 1 total inactive lever presses1.01.32.70.60.40.50.4-0.4-0.50.61.11.5-1.31.5-0.41.51.41.51.51.6-0.5-1.1-1.2-1.31.31.60.01.7
Short access day 10 total inactive lever presses0.71.85.11.91.81.81.8-1.8-0.80.81.61.3-1.41.1-0.31.11.11.20.91.0-2.31.41.5-0.40.5-1.3-0.8-0.7
Short access day 1 total infusions0.81.03.2-1.3-1.2-1.2-1.21.21.1-0.7-0.7-0.20.7-0.21.1-0.2-0.2-0.2-0.2-0.31.2-1.8-1.8-1.20.11.80.21.3
Short access day 10 total infusions0.20.31.4-0.7-0.5-0.5-0.50.50.2-0.3-0.5-0.60.6-0.40.1-0.4-0.3-0.1-0.0-0.41.2-0.3-0.40.50.10.41.10.5
Short access total infusions0.30.41.5-1.0-0.7-0.8-0.70.70.3-0.2-0.5-0.30.6-0.20.1-0.2-0.1-0.10.1-0.31.2-1.0-1.1-0.00.21.20.80.9
Short access day 1 locomotion0.81.03.2-1.3-1.2-1.2-1.21.21.2-0.9-1.1-0.91.0-0.71.4-0.7-0.7-0.6-0.8-0.81.8-1.1-1.1-0.6-0.11.00.90.8
Short access day 10 total locomotion1.01.97.5-0.20.1-0.10.1-0.10.10.70.91.6-0.91.50.41.51.61.41.31.3-0.0-2.2-2.3-2.21.42.70.02.4
Short access total locomotion1.01.25.4-0.2-0.00.0-0.00.0-0.00.50.50.8-0.61.00.21.11.01.31.00.81.3-1.3-1.5-1.21.62.01.82.3
One hour access (0.3 mA shock)0.91.05.50.10.30.30.3-0.3-0.60.3-0.1-0.10.4-0.5-0.8-0.5-0.4-0.9-0.7-0.5-1.80.81.01.7-1.4-1.4-2.3-2.0
Compulsive drug intake0.50.52.80.50.30.50.3-0.3-0.80.40.20.3-0.2-0.1-0.80.0-0.2-0.4-0.00.2-1.50.90.80.9-0.7-1.0-1.7-1.4
One hour access (shock baseline)0.10.21.2-0.10.20.10.2-0.2-0.20.1-0.1-0.40.3-0.3-0.4-0.3-0.1-0.3-0.5-0.40.20.40.51.1-0.2-0.60.4-0.4
Social response proportion2.32.612.21.21.31.21.3-1.3-0.70.3-0.1-0.90.5-0.9-0.6-0.7-0.8-0.7-0.9-0.9-0.83.23.33.0-0.8-3.50.6-2.6
Social responses2.22.89.80.10.20.10.2-0.20.1-0.4-1.1-2.01.5-1.80.1-1.8-1.7-1.8-2.0-1.90.52.62.63.0-1.4-3.10.8-2.7
Social time0.60.85.80.50.50.50.6-0.6-1.10.5-0.1-0.60.2-0.4-1.1-0.5-0.4-0.5-0.30.0-0.41.61.52.4-0.5-1.60.2-1.4
Soleus weight0.20.51.90.30.20.20.2-0.2-0.80.2-0.1-0.7-0.1-0.6-0.8-0.7-0.7-0.7-0.5-0.4-0.11.21.11.4-0.6-1.20.1-1.2
Bone: stiffness1.21.93.51.91.81.81.7-1.7-1.81.41.61.2-1.81.2-1.31.21.21.31.21.4-1.41.31.40.91.0-0.90.4-0.2
Tibialis anterior weight0.41.45.31.11.11.01.0-1.0-1.50.90.4-0.3-0.4-0.2-1.5-0.3-0.4-0.5-0.30.0-1.12.12.12.3-0.5-2.0-0.1-1.9
Time to tail flick, vehicle, before self-admin0.50.51.9-0.1-0.2-0.1-0.10.10.00.30.30.6-0.50.7-0.00.80.60.80.90.50.7-0.8-0.9-1.10.91.20.91.4
Time to tail flick, vehicle, after self-admin0.10.21.00.00.10.00.1-0.1-0.60.70.30.4-0.20.4-1.00.30.40.20.60.6-0.3-0.3-0.40.00.20.5-0.40.2
Time to tail flick, test, before self-admin0.10.10.70.0-0.0-0.1-0.00.0-0.20.10.00.0-0.2-0.1-0.20.2-0.00.30.3-0.00.70.10.00.10.40.10.80.4
Time to tail flick, test, after self-admin0.50.61.80.80.70.60.7-0.7-1.20.90.80.7-0.80.7-1.30.80.70.81.00.9-0.20.40.30.70.8-0.00.70.3
Delta time to tail flick, vehicle, before/after SA1.31.34.01.31.41.31.4-1.4-1.41.31.10.8-0.70.6-1.50.50.80.40.60.8-2.01.21.21.10.0-1.1-1.1-1.1
Delta time to tail flick, test, before/after SA0.10.10.40.20.30.30.3-0.3-0.50.40.30.1-0.10.3-0.60.10.30.20.30.5-0.10.10.00.50.20.10.30.1
Tibia length0.92.45.61.51.31.31.3-1.3-0.91.21.71.6-1.92.0-0.41.91.92.21.72.00.3-0.1-0.2-1.02.41.02.22.0
Ambulatory time before self-admin0.40.61.60.60.80.70.8-0.8-0.91.01.00.8-0.91.0-0.70.81.11.01.11.3-0.4-0.1-0.10.00.90.50.30.7
Ambulatory time after self-admin0.20.31.0-0.2-0.0-0.2-0.10.10.0-0.1-0.4-0.70.5-0.70.3-0.6-0.6-0.7-0.6-0.7-0.00.60.61.0-0.6-0.8-0.2-0.9
Bone: tissue strength0.40.41.00.50.50.50.5-0.5-0.10.20.80.9-0.90.90.40.80.90.80.60.8-0.4-0.4-0.3-1.00.70.6-0.00.8
Total heroin consumption0.81.03.9-1.2-1.0-1.1-1.01.01.4-0.8-0.5-0.10.6-0.21.3-0.3-0.1-0.3-0.2-0.30.6-1.7-1.6-2.0-0.31.5-0.80.9
Bone: trabecular number1.32.25.61.81.81.81.8-1.8-1.71.61.81.6-1.81.4-1.61.41.41.31.41.5-2.41.11.20.10.6-0.8-1.0-0.6
Bone: trabecular spacing0.70.95.5-0.9-1.0-1.0-1.01.00.8-0.6-1.0-1.20.9-0.70.6-0.8-0.7-0.6-0.8-0.92.3-0.5-0.60.20.20.51.90.8
Bone: trabecular thickness0.50.61.8-0.3-0.3-0.3-0.30.3-0.0-0.3-0.7-0.70.8-0.8-0.3-0.9-0.9-0.9-0.6-0.8-0.60.50.61.2-1.2-0.9-1.2-1.4
Bone: trabecular tissue density2.74.010.5-2.1-2.1-2.1-2.12.12.4-2.6-2.2-1.62.1-2.02.2-2.1-2.1-2.2-2.0-2.1-0.4-1.3-1.0-0.9-2.7-0.1-3.2-1.3
Water consumed over 24 hours0.30.41.6-0.2-0.2-0.2-0.20.2-0.1-0.2-0.6-0.70.6-0.7-0.0-0.7-0.8-0.9-0.8-0.90.00.70.61.3-0.7-0.9-0.2-1.0
Number of responses in last shaping day0.40.51.9-0.8-0.7-0.6-0.70.70.8-0.7-0.5-0.60.5-0.41.0-0.4-0.4-0.4-0.5-0.31.4-0.6-0.7-0.50.10.61.20.6