Hub : Genes

Ccdc12

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Brain intron excision ratio chr8_110668671_110683304 0.05 0.04 2.9e-05 0.04 0.04 0.05 0.04 1.3e-04 6.0e-05 3.5e-05 6.2e-05
2 Brain mRNA stability Ccdc12 0.15 0.1 4.6e-14 0.15 0.16 0.15 0.16 7.2e-14 2.5e-14 4.9e-14 2.2e-14
3 PL alternative TSS NM_001108783.1 0.05 0.06 2.8e-04 0.02 0.02 0.01 0.02 5.7e-03 1.2e-03 7.4e-03 4.1e-03
4 PL alternative TSS XM_006243970.4 0.05 0.05 4.8e-05 0.02 0.03 0.02 0.02 1.8e-03 1.7e-04 2.8e-03 1.6e-03
5 PL isoform ratio NM_001108783.1 0.04 0.04 2.9e-04 0.02 0.03 0.02 0.02 4.6e-03 4.4e-04 3.4e-03 2.5e-03
6 PL isoform ratio XM_006243970.4 0.05 0.04 6.6e-05 0.02 0.03 0.02 0.02 2.3e-03 1.4e-04 2.0e-03 2.0e-03
7 NAcc intron excision ratio chr8_110668671_110683304 0.03 0.03 2.1e-03 0.01 0.01 0.01 0 6.7e-02 1.0e-02 2.1e-02 7.5e-02
8 NAcc isoform ratio NM_001108783.1 0.03 0.03 1.2e-03 0.02 0.02 0.02 0.02 1.9e-03 9.0e-04 2.1e-03 2.0e-03
9 NAcc gene expression Ccdc12 0.08 0.06 1.1e-08 0.06 0.06 0.05 0.05 1.1e-07 3.4e-07 3.0e-06 1.9e-06
10 NAcc alternative TSS NM_001108783.1 0.02 0.02 5.3e-03 0.02 0.02 0.01 0.02 5.2e-03 3.5e-03 7.5e-03 5.0e-03
11 NAcc alternative TSS XM_006243970.4 0.03 0.03 9.6e-04 0.02 0.03 0.02 0.02 1.3e-03 5.9e-04 1.4e-03 1.3e-03
12 NAcc isoform ratio XM_006243970.4 0.03 0.03 5.9e-04 0.02 0.03 0.02 0.02 1.2e-03 4.1e-04 1.7e-03 1.2e-03
13 PL intron excision ratio chr8_110635434_110635523 0.02 0.02 4.8e-03 0.01 0.02 0.01 0.01 1.4e-02 3.0e-03 1.3e-02 1.1e-02
14 Brain gene expression Ccdc12 0.05 0.04 1.2e-04 0.03 0.04 0.03 0.03 1.4e-03 3.0e-04 8.2e-04 1.7e-03
15 Brain intron excision ratio chr8_110635863_110668604 0.04 0.04 2.6e-04 0.03 0.03 0.03 0.03 1.0e-03 4.5e-04 5.5e-04 8.6e-04
16 Eye gene expression Ccdc12 0.33 0.24 4.1e-03 0.07 0.08 0.03 0.07 3.7e-02 2.1e-02 1.0e-01 2.8e-02
17 PL gene expression Ccdc12 0.09 0.16 4.6e-05 0.03 0.02 0.02 0.02 5.4e-04 9.5e-04 6.4e-03 1.2e-03
18 BLA gene expression Ccdc12 0.12 0.12 2.5e-05 0.07 0.08 0.06 0.08 8.0e-05 5.9e-05 3.8e-04 6.2e-05
19 PL mRNA stability Ccdc12 0.04 0.04 1.9e-04 0.02 0.03 0.03 0.03 1.6e-03 3.1e-04 4.0e-04 6.2e-04
20 RMTg gene expression Ccdc12 0.27 0.18 2.5e-05 0.14 0.12 0.08 0.12 1.2e-04 3.2e-04 3.0e-03 3.2e-04
21 LHb gene expression Ccdc12 0.48 0.24 2.9e-06 0.12 0.14 0.12 0.14 1.1e-03 2.9e-04 8.5e-04 2.9e-04
22 pVTA gene expression Ccdc12 0.63 0.23 1.4e-10 0.19 0.19 0.18 0.19 8.7e-09 1.5e-08 2.5e-08 1.3e-08
23 IL gene expression Ccdc12 0.15 0.13 6.2e-03 0.06 0.06 0.06 0.05 1.3e-02 1.4e-02 1.6e-02 2.0e-02
24 LHb alternative TSS NM_001108783.1 0.85 0.11 6.2e-03 -0 0.06 0.04 0.03 4.0e-01 1.9e-02 3.3e-02 6.2e-02
25 NAcc intron excision ratio chr8_110635863_110668604 0.02 0.03 4.5e-03 0 0.01 0.02 0 9.4e-02 1.1e-02 5.0e-03 8.0e-02

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25
Bone: apparent density0.00.10.30.20.2-0.20.2-0.20.2-0.2-0.20.2-0.20.20.20.2-0.20.2-0.20.2-0.20.20.20.20.2-0.4-0.30.6
Area under the delay curve2.22.43.0-1.5-1.61.6-1.61.6-1.61.61.6-1.51.6-1.6-1.6-1.61.6-1.51.6-1.61.6-1.6-1.51.7-1.5-1.70.71.3
BMI with tail0.62.012.51.01.3-1.21.2-1.21.1-1.1-1.11.4-1.11.11.11.1-1.21.1-1.11.5-1.11.10.8-1.50.71.5-3.5-2.2
BMI without tail1.93.86.91.92.0-2.02.0-2.02.0-2.0-2.02.2-2.02.02.01.9-2.01.9-1.92.2-1.91.91.8-1.71.41.6-2.6-1.9
Body weight6.828.331.55.45.6-5.55.4-5.45.4-5.4-5.45.6-5.45.45.45.4-5.45.4-5.45.6-5.45.45.2-5.44.95.1-4.2-4.6
Weight adjusted by age0.20.20.40.40.4-0.50.5-0.50.5-0.5-0.50.7-0.50.50.50.5-0.50.5-0.50.6-0.50.50.5-0.20.5-0.0-0.2-0.4
Bone surface0.10.10.5-0.3-0.20.2-0.20.2-0.30.30.3-0.10.3-0.3-0.3-0.30.2-0.30.3-0.10.3-0.3-0.30.5-0.3-0.6-0.70.0
Bone volume0.00.00.5-0.1-0.00.0-0.10.1-0.10.10.10.00.1-0.1-0.1-0.10.1-0.10.10.00.1-0.1-0.20.4-0.2-0.5-0.70.1
Breakpoint value in progressive ratio session0.10.10.90.70.2-0.30.3-0.30.3-0.3-0.3-0.0-0.30.30.30.3-0.30.3-0.30.0-0.30.30.3-0.50.30.60.10.9
Number of licking bursts0.10.20.4-0.4-0.40.5-0.40.4-0.40.40.4-0.40.4-0.4-0.4-0.40.4-0.40.4-0.40.4-0.4-0.40.0-0.40.20.60.1
Context. condit. distance diff. score0.00.00.1-0.00.0-0.00.0-0.00.0-0.0-0.00.1-0.00.00.00.0-0.00.0-0.00.1-0.00.00.0-0.0-0.10.0-0.0-0.3
Locomotion velocity, session 10.10.10.2-0.4-0.20.2-0.20.2-0.30.30.2-0.10.2-0.2-0.2-0.20.2-0.30.2-0.10.2-0.2-0.30.3-0.3-0.4-0.40.3
Locomotion distance, session 10.91.24.61.01.3-1.11.1-1.11.0-1.0-1.11.3-1.01.11.11.0-1.11.0-1.01.3-1.01.00.8-0.90.90.7-2.1-0.7
Locomotion velocity, session 20.20.30.7-0.6-0.40.5-0.50.5-0.50.50.5-0.40.5-0.5-0.5-0.60.5-0.60.6-0.40.6-0.6-0.70.4-0.6-0.4-0.8-0.2
Locomotion distance, session 20.10.23.0-0.30.20.0-0.10.1-0.10.10.10.20.1-0.1-0.1-0.10.0-0.10.10.20.1-0.1-0.30.4-0.3-0.6-1.70.1
Locomotion velocity, session 30.20.22.60.20.4-0.40.3-0.30.3-0.3-0.30.5-0.30.30.30.3-0.30.3-0.30.5-0.30.30.20.3-0.0-0.6-1.60.1
Locomotion distance, session 31.01.12.4-1.2-0.91.0-1.01.0-1.01.01.0-0.81.0-1.0-1.0-1.01.0-1.11.0-0.81.0-1.0-1.21.4-1.3-1.6-1.10.7
Stereotopy head waving bouts, day 30.10.10.90.30.2-0.20.2-0.20.2-0.2-0.20.2-0.20.20.20.2-0.20.2-0.20.2-0.20.20.2-0.70.21.00.3-0.9
Stereotopy head waving duration, day 30.30.30.60.60.5-0.50.5-0.50.6-0.6-0.60.5-0.60.60.60.6-0.60.6-0.60.5-0.60.60.6-0.70.50.80.7-0.4
Locomotion velocity, session 70.30.30.50.30.6-0.50.5-0.50.5-0.5-0.50.6-0.50.50.50.6-0.60.5-0.60.6-0.60.60.60.20.2-0.5-0.10.7
Locomotion distance, session 70.70.92.8-1.1-0.80.8-0.80.8-0.80.80.9-0.70.8-0.9-0.9-0.80.8-0.90.8-0.70.8-0.8-0.91.5-1.2-1.70.21.4
Stereotopy head waving bouts, day 70.10.10.2-0.2-0.30.3-0.30.3-0.30.30.3-0.40.3-0.3-0.3-0.30.3-0.20.3-0.40.3-0.3-0.20.2-0.1-0.20.30.1
Stereotopy head waving duration, day 70.20.20.40.60.5-0.50.5-0.50.5-0.5-0.50.4-0.50.50.50.5-0.50.5-0.50.4-0.50.50.5-0.60.60.5-0.3-0.4
Locomotion velocity, session 80.40.44.10.40.7-0.60.5-0.50.5-0.5-0.50.8-0.50.50.50.5-0.50.5-0.50.8-0.50.50.3-0.20.20.0-2.0-0.4
Locomotion distance, session 80.30.55.10.30.8-0.60.6-0.60.6-0.5-0.60.9-0.50.50.50.5-0.60.5-0.50.9-0.50.50.30.00.2-0.4-2.3-0.2
Degree of sensitization distance1.21.21.51.21.1-1.11.1-1.11.1-1.2-1.11.0-1.21.11.11.2-1.11.2-1.21.0-1.21.21.2-1.11.21.00.6-0.2
Degree of sensitization stereotypy0.00.00.10.2-0.1-0.00.1-0.10.1-0.1-0.1-0.2-0.00.00.00.00.00.1-0.0-0.2-0.00.00.2-0.00.3-0.10.30.1
Conditioned locomotion3.13.74.3-1.9-2.02.0-1.91.9-1.91.91.9-2.01.9-1.9-1.9-1.92.0-1.91.9-2.01.9-1.9-1.82.1-1.8-2.01.51.6
Cocaine response after cond. corrected0.30.41.70.60.5-0.50.5-0.50.5-0.5-0.50.4-0.50.50.50.5-0.50.5-0.50.4-0.50.50.5-1.10.51.30.2-1.2
Cocaine response after cond. not corrected1.92.13.71.51.4-1.41.4-1.41.4-1.4-1.41.4-1.41.41.41.4-1.41.4-1.41.4-1.41.41.4-1.81.41.9-0.6-1.7
Cocaine response before conditioning1.21.42.91.11.3-1.31.2-1.21.2-1.2-1.21.4-1.21.21.21.2-1.21.2-1.21.4-1.21.21.1-0.81.20.5-1.7-0.6
Saline control response1.21.62.21.41.3-1.31.4-1.41.4-1.4-1.41.3-1.41.41.41.4-1.41.4-1.41.3-1.41.41.4-1.01.50.70.1-0.0
Bone: connectivity density0.30.52.1-0.5-0.70.6-0.60.6-0.60.60.6-0.60.6-0.6-0.6-0.60.6-0.50.6-0.60.5-0.6-0.51.0-0.4-1.30.71.4
Bone: cortical apparent density0.30.40.6-0.6-0.70.6-0.60.6-0.60.60.6-0.70.6-0.6-0.6-0.60.6-0.60.6-0.70.6-0.6-0.40.7-0.4-0.80.70.6
Bone: cortical area0.10.20.7-0.5-0.40.4-0.40.4-0.40.40.4-0.40.4-0.4-0.4-0.40.4-0.40.4-0.40.4-0.4-0.40.1-0.40.10.2-0.8
Bone: cortical porosity0.20.22.2-0.1-0.30.2-0.20.2-0.20.20.2-0.40.2-0.2-0.2-0.20.2-0.20.2-0.40.2-0.2-0.10.60.0-0.71.21.5
Bone: cortical porosity0.40.43.1-0.4-0.50.5-0.40.4-0.40.40.4-0.60.4-0.4-0.4-0.40.4-0.40.4-0.60.4-0.4-0.30.8-0.2-1.01.41.8
Bone: cortical thickness0.20.32.70.40.4-0.40.4-0.40.4-0.4-0.40.4-0.40.40.40.4-0.40.4-0.40.4-0.40.40.4-0.90.31.1-0.2-1.6
Bone: cortical thickness0.00.00.00.00.1-0.10.1-0.10.1-0.1-0.10.1-0.10.10.10.1-0.10.1-0.10.1-0.10.10.1-0.1-0.00.10.0-0.0
Bone: cortical tissue density0.30.40.6-0.6-0.70.6-0.60.6-0.60.60.6-0.70.6-0.6-0.6-0.60.6-0.60.6-0.70.6-0.6-0.50.7-0.4-0.80.70.7
Condit. Reinf. active minus inactive responses0.10.10.70.30.2-0.30.3-0.30.3-0.3-0.30.2-0.30.30.30.3-0.30.3-0.30.2-0.30.30.4-0.30.40.40.8-0.1
Condit. Reinf. active-inactive response ratio0.30.30.70.50.4-0.50.5-0.50.5-0.5-0.50.4-0.50.50.50.5-0.50.5-0.50.4-0.50.50.6-0.70.60.80.9-0.4
Condit. Reinf. active responses0.00.00.6-0.1-0.30.2-0.20.1-0.10.10.1-0.20.1-0.1-0.1-0.10.2-0.10.1-0.20.1-0.1-0.00.0-0.10.00.8-0.2
Condit. Reinf. inactive responses0.60.71.0-0.8-1.00.9-0.90.9-0.90.90.9-0.90.9-0.9-0.9-0.90.9-0.90.9-0.90.9-0.9-0.80.8-0.9-0.80.10.1
Incentive salience index mean0.00.10.1-0.3-0.30.2-0.20.2-0.20.20.2-0.20.2-0.2-0.2-0.20.2-0.20.2-0.20.2-0.2-0.30.2-0.2-0.20.1-0.1
Condit. Reinf. lever presses1.41.92.4-1.5-1.41.4-1.41.4-1.41.41.4-1.21.4-1.4-1.4-1.41.4-1.51.4-1.21.4-1.4-1.61.4-1.5-1.3-0.20.5
Condit. Reinf. active minus inactive responses2.22.73.31.71.8-1.71.7-1.71.7-1.7-1.71.8-1.71.71.71.7-1.71.6-1.71.8-1.71.71.6-1.81.51.7-1.4-1.3
Condit. Reinf. active-inactive response ratio1.81.92.61.41.5-1.41.4-1.41.4-1.4-1.41.4-1.41.41.41.4-1.41.3-1.31.4-1.31.41.3-1.61.21.6-1.3-1.4
Condit. Reinf. active responses1.82.52.91.61.7-1.61.6-1.61.6-1.6-1.61.6-1.61.61.61.6-1.61.6-1.61.6-1.61.61.6-1.71.61.6-1.0-1.3
Condit. Reinf. inactive responses0.00.00.1-0.2-0.20.1-0.10.1-0.10.10.1-0.10.1-0.1-0.1-0.10.1-0.10.1-0.10.1-0.1-0.10.20.1-0.20.30.3
Condit. Reinf. lever presses2.63.54.21.92.0-1.91.9-1.91.9-1.9-1.92.0-1.91.91.91.9-1.91.8-1.92.0-1.81.91.8-2.01.71.9-1.8-1.5
Condit. Reinf. lever reinforcers received2.02.93.31.71.8-1.71.7-1.71.7-1.7-1.71.8-1.71.71.71.7-1.71.7-1.71.8-1.71.71.6-1.81.71.7-1.1-1.3
Conditioned reinforcement - actives0.30.30.7-0.6-0.70.5-0.60.6-0.60.50.5-0.30.5-0.5-0.5-0.50.5-0.60.5-0.20.5-0.5-0.70.5-0.7-0.4-0.10.9
Conditioned reinforcement - inactives0.80.91.3-1.1-1.01.0-1.01.0-1.01.01.0-0.91.0-1.0-1.0-1.01.0-1.01.0-1.01.0-1.0-1.00.7-1.2-0.40.4-0.3
Conditioned locomotion0.40.51.6-0.7-0.80.7-0.70.7-0.70.70.6-0.50.6-0.6-0.6-0.60.6-0.70.6-0.50.6-0.6-0.80.7-0.6-0.7-0.11.3
Patch foraging indifference point 0 sec0.91.41.91.21.4-1.31.3-1.31.3-1.3-1.31.2-1.31.31.31.3-1.31.3-1.31.2-1.31.31.4-0.71.20.3-0.20.0
Patch foraging indifference point AUC0.10.10.20.40.2-0.30.3-0.30.3-0.3-0.30.1-0.30.30.30.3-0.20.3-0.30.1-0.30.30.4-0.30.20.2-0.30.0
Delay disc. indifference point, 0s delay0.00.00.2-0.2-0.20.2-0.20.2-0.20.20.2-0.10.2-0.2-0.2-0.20.2-0.20.2-0.20.2-0.2-0.20.2-0.2-0.1-0.10.4
Delay disc. indifference point, 16s delay1.11.12.4-1.1-1.01.1-1.11.1-1.11.11.1-1.01.1-1.1-1.1-1.11.1-1.11.1-1.01.1-1.1-1.01.4-1.0-1.50.30.9
Delay disc. indifference point, 2s delay0.30.40.7-0.6-0.70.6-0.60.6-0.60.60.6-0.60.6-0.6-0.6-0.60.6-0.60.6-0.70.6-0.6-0.50.8-0.6-0.90.20.4
Delay disc. indifference point, 24s delay1.00.92.1-0.9-0.91.0-0.90.9-0.90.90.9-1.00.9-0.9-0.9-0.91.0-0.90.9-1.01.0-0.9-0.91.3-0.9-1.50.50.7
Delay disc. indifference point, 4s delay2.22.32.6-1.5-1.61.6-1.61.6-1.61.61.6-1.51.6-1.6-1.6-1.61.6-1.61.6-1.61.6-1.6-1.51.6-1.6-1.50.71.1
Delay disc. indifference point, 8s delay2.22.22.9-1.5-1.61.5-1.51.5-1.51.51.5-1.51.5-1.5-1.5-1.51.5-1.51.5-1.51.5-1.5-1.51.7-1.5-1.70.71.1
Indifference point function ln k0.20.31.9-0.8-0.20.4-0.40.4-0.40.40.4-0.10.4-0.4-0.4-0.40.4-0.50.4-0.00.4-0.5-0.60.8-0.6-0.9-1.4-0.1
Indifference point function log k0.20.31.9-0.8-0.20.4-0.40.4-0.40.40.4-0.10.4-0.4-0.4-0.40.4-0.50.4-0.00.4-0.5-0.60.8-0.6-0.9-1.4-0.1
Patch foraging total patch changes 0 sec1.11.72.21.31.5-1.41.4-1.41.4-1.4-1.41.3-1.41.41.41.4-1.41.4-1.41.3-1.41.41.5-0.91.40.7-0.2-0.3
Patch foraging total patch changes 12 sec0.81.01.61.21.1-1.11.1-1.11.1-1.1-1.10.9-1.11.11.11.1-1.01.1-1.10.9-1.11.11.3-0.91.20.70.0-0.4
Patch foraging total patch changes 18 sec2.43.03.81.91.6-1.81.8-1.81.8-1.9-1.91.7-1.91.91.91.9-1.91.9-1.91.7-1.91.91.9-1.61.71.50.30.2
Patch foraging total patch changes 24 sec3.03.64.32.02.1-2.02.0-2.02.0-2.0-2.01.9-2.02.02.02.0-2.02.0-2.01.9-1.92.02.0-2.01.91.9-0.9-1.1
Patch foraging total patch changes 6 sec0.10.10.30.40.4-0.40.4-0.40.4-0.4-0.40.2-0.40.40.40.4-0.40.4-0.40.2-0.40.40.6-0.10.5-0.10.20.3
Patch foraging time to switch 0 sec0.10.20.6-0.4-0.40.5-0.50.5-0.50.50.5-0.40.5-0.5-0.5-0.50.5-0.40.5-0.50.5-0.5-0.50.1-0.30.00.8-0.1
Patch foraging water rate 0 sec0.10.20.30.40.5-0.50.5-0.50.5-0.5-0.50.5-0.50.50.50.5-0.50.5-0.50.5-0.50.50.4-0.50.50.4-0.6-0.3
Patch foraging water rate 12 sec0.30.50.90.60.9-0.70.7-0.70.7-0.7-0.70.8-0.70.70.70.7-0.70.7-0.70.8-0.70.70.6-0.80.40.9-0.9-0.9
Patch foraging water rate 18 sec0.10.22.2-0.00.4-0.20.2-0.10.1-0.1-0.10.2-0.10.10.10.1-0.20.1-0.10.2-0.10.1-0.0-0.3-0.10.4-1.5-1.1
Patch foraging water rate 24 sec0.70.91.31.10.9-1.01.0-1.01.0-1.0-1.00.9-1.01.01.01.0-1.01.0-1.00.9-1.01.01.1-1.11.01.1-0.3-0.8
Patch foraging water rate 6 sec0.40.51.60.60.9-0.70.7-0.70.7-0.7-0.70.8-0.70.70.70.7-0.70.7-0.70.8-0.70.70.5-0.60.70.4-1.3-0.6
Seeking ratio, delayed vs. immediate footshock2.42.83.6-1.6-1.71.8-1.81.8-1.81.81.8-1.71.8-1.8-1.8-1.81.8-1.81.8-1.91.8-1.7-1.81.2-1.8-0.80.91.2
Distance traveled before self-admin0.10.11.3-0.30.2-0.10.1-0.10.1-0.1-0.1-0.1-0.10.10.10.1-0.10.1-0.10.1-0.10.10.10.0-0.1-0.10.1-1.1
Distance traveled after self-admin0.20.20.8-0.8-0.20.5-0.40.5-0.50.50.5-0.50.5-0.5-0.5-0.50.4-0.50.5-0.30.4-0.5-0.40.6-0.7-0.60.2-0.9
Extensor digitorum longus weight0.10.60.7-0.8-0.70.8-0.80.8-0.80.80.8-0.70.8-0.8-0.8-0.80.8-0.80.8-0.70.8-0.8-0.80.6-0.8-0.40.20.1
Bone: elastic displacement0.10.10.40.20.3-0.20.2-0.20.2-0.2-0.20.2-0.20.20.20.2-0.20.2-0.20.2-0.20.20.2-0.50.30.7-0.0-0.6
Bone: elastic work0.60.81.70.81.0-0.90.8-0.80.8-0.8-0.81.0-0.80.80.80.8-0.80.8-0.81.0-0.80.80.7-1.00.71.0-1.3-1.3
Bone: endosteal estimation0.10.20.40.40.5-0.40.4-0.40.4-0.4-0.40.4-0.40.40.40.4-0.40.4-0.40.4-0.40.40.40.00.3-0.20.30.6
Bone: endosteal perimeter1.12.33.0-1.7-1.51.6-1.61.6-1.61.61.6-1.51.6-1.6-1.6-1.61.5-1.61.6-1.51.6-1.6-1.61.7-1.5-1.70.40.7
Epididymis fat weight0.30.82.81.10.7-0.80.8-0.80.8-0.8-0.80.7-0.80.80.80.8-0.80.8-0.80.7-0.80.80.8-1.40.71.7-0.2-1.1
Delta time in closed arm before/after self-admin0.10.10.3-0.2-0.40.4-0.40.4-0.40.40.4-0.50.4-0.4-0.4-0.40.4-0.40.4-0.30.4-0.4-0.40.1-0.30.00.10.6
Delta time in open arm before/after self-admin0.30.30.80.10.6-0.50.5-0.50.5-0.5-0.50.8-0.50.50.50.5-0.50.5-0.50.6-0.50.50.60.20.3-0.5-0.1-0.9
Diff in mean of infusions in LGA sessions0.10.10.60.1-0.20.1-0.10.1-0.10.10.1-0.10.1-0.1-0.1-0.10.1-0.10.1-0.10.1-0.1-0.1-0.60.10.80.2-0.5
Delay discount exponential model param2.62.73.31.61.7-1.71.7-1.71.7-1.7-1.71.7-1.71.71.71.7-1.71.7-1.71.8-1.71.71.6-1.81.71.8-0.7-1.2
Extinction: sum of active levers before priming0.00.00.80.20.1-0.10.1-0.10.1-0.1-0.10.2-0.10.10.10.1-0.10.1-0.10.0-0.10.10.2-0.00.0-0.00.20.9
Active lever presses in extinction session 60.30.30.50.30.5-0.50.5-0.50.5-0.5-0.50.3-0.50.50.60.5-0.60.5-0.60.4-0.60.60.60.30.4-0.7-0.00.4
Bone: final force0.91.53.31.21.3-1.21.2-1.21.2-1.2-1.21.2-1.21.21.21.2-1.21.2-1.21.2-1.11.21.1-1.51.21.5-0.7-1.8
Bone: final moment1.21.94.11.41.5-1.41.3-1.31.3-1.3-1.31.4-1.31.31.31.3-1.31.3-1.31.4-1.31.31.3-1.71.41.7-0.9-2.0
Food consumed during 24 hour testing period1.41.72.01.31.4-1.41.3-1.31.3-1.3-1.31.4-1.31.31.31.3-1.41.3-1.31.4-1.31.31.2-1.31.41.2-1.1-1.0
Glucose0.30.40.70.80.7-0.70.7-0.60.6-0.6-0.60.6-0.60.60.60.6-0.60.6-0.60.6-0.60.60.6-0.60.70.4-0.80.0
Heart weight2.84.07.92.02.1-1.91.9-1.91.9-1.9-1.91.9-1.91.91.91.9-1.91.9-1.91.9-1.91.91.9-2.52.12.5-1.3-2.8
Delay discount hyperbolic model param2.62.73.31.61.7-1.71.7-1.71.7-1.7-1.71.7-1.71.71.71.7-1.71.7-1.71.8-1.71.71.6-1.81.71.8-0.7-1.2
Intermittent access intake day 1-15 change0.50.50.8-0.9-0.80.7-0.70.7-0.70.70.7-0.60.7-0.7-0.7-0.70.7-0.70.7-0.50.7-0.7-0.70.5-0.7-0.40.3-0.7
Intermittent access intake escalation0.40.40.7-0.8-0.70.6-0.60.6-0.60.60.6-0.50.6-0.6-0.6-0.60.6-0.60.6-0.40.6-0.6-0.60.6-0.7-0.50.3-0.5
Intermittent access intake escalation 20.10.11.3-0.10.1-0.20.2-0.20.2-0.2-0.20.3-0.20.20.20.2-0.20.2-0.20.4-0.20.20.0-0.20.20.2-0.1-1.1
Intermitt. access day 1 inactive lever presses0.00.00.1-0.1-0.00.0-0.00.0-0.00.00.00.10.0-0.0-0.0-0.10.0-0.10.1-0.10.1-0.1-0.30.10.1-0.2-0.30.1
Intermitt. access day 15 inactive lever presses0.70.71.0-0.9-0.80.9-0.90.9-0.90.90.9-0.90.9-0.9-0.9-0.90.9-0.90.9-1.00.9-0.9-0.80.7-1.0-0.60.4-0.3
Intermitt. access escalation Index0.10.10.7-0.10.0-0.00.0-0.00.0-0.0-0.0-0.0-0.00.00.00.0-0.00.0-0.0-0.1-0.00.0-0.10.5-0.0-0.7-0.10.8
Intermittent access day 1 total infusions0.00.00.1-0.2-0.20.1-0.10.1-0.10.10.1-0.00.1-0.1-0.1-0.10.1-0.10.1-0.10.1-0.1-0.20.3-0.3-0.3-0.10.4
Intermittent access day 15 total infusions0.30.30.6-0.8-0.70.6-0.60.6-0.60.50.5-0.40.5-0.5-0.5-0.50.5-0.60.5-0.40.5-0.5-0.60.8-0.7-0.70.20.0
Intermittent access terminal intake (last 3 days)0.10.20.6-0.6-0.50.3-0.40.4-0.40.30.3-0.20.3-0.3-0.3-0.30.3-0.40.3-0.20.3-0.3-0.40.7-0.5-0.80.00.3
Intermittent access total infusions0.50.51.1-0.9-0.80.7-0.70.7-0.70.70.7-0.60.7-0.7-0.7-0.70.6-0.70.7-0.60.7-0.6-0.81.0-0.8-1.10.00.7
Intermittent access day 1 locomotion0.10.10.5-0.4-0.40.3-0.30.3-0.30.30.3-0.20.3-0.3-0.3-0.30.3-0.30.3-0.30.3-0.3-0.30.5-0.6-0.40.00.7
Intermittent access day 15 total locomotion0.70.72.0-0.9-0.90.8-0.80.8-0.80.80.8-0.70.8-0.8-0.7-0.70.7-0.80.7-0.60.7-0.7-0.91.3-0.9-1.40.31.3
Intermittent access total locomotion1.21.42.2-1.3-1.31.1-1.21.2-1.21.21.1-1.11.1-1.1-1.1-1.11.1-1.21.1-1.11.1-1.1-1.21.4-1.1-1.50.21.3
Intermittent access standard deviation0.30.31.70.30.4-0.50.5-0.50.5-0.5-0.50.6-0.50.50.50.5-0.50.5-0.50.7-0.50.50.5-0.60.30.7-0.2-1.3
Left kidney weight0.82.27.91.51.6-1.51.5-1.41.4-1.4-1.41.5-1.41.41.41.4-1.41.4-1.31.5-1.31.31.4-1.31.41.0-2.8-1.7
Right kidney weight0.20.53.20.60.7-0.70.7-0.70.7-0.6-0.70.7-0.60.60.60.6-0.60.6-0.60.7-0.60.60.7-0.20.7-0.2-1.8-0.7
Cocaine induced anxiety0.50.60.8-0.9-0.80.8-0.80.8-0.80.80.8-0.90.8-0.8-0.8-0.80.8-0.80.8-0.90.8-0.8-0.80.6-0.7-0.50.4-0.2
Post-drug Anxiety0.20.20.4-0.5-0.40.5-0.50.5-0.50.50.5-0.70.5-0.5-0.5-0.50.6-0.50.5-0.70.5-0.5-0.40.2-0.4-0.10.4-0.4
Baseline Anxiety0.20.20.4-0.4-0.30.4-0.40.4-0.40.40.4-0.30.4-0.4-0.4-0.40.4-0.40.4-0.30.4-0.4-0.30.6-0.6-0.60.30.6
Tail length6.519.723.14.84.6-4.74.7-4.74.7-4.7-4.74.6-4.74.74.74.7-4.64.7-4.74.5-4.74.74.7-4.14.33.7-1.3-2.5
Length with tail9.233.838.26.26.1-6.16.1-6.16.1-6.1-6.16.0-6.16.16.16.1-6.06.1-6.15.9-6.16.06.1-5.65.85.0-2.3-3.8
Length without tail6.414.015.83.93.9-3.83.8-3.83.8-3.8-3.83.8-3.83.83.83.8-3.83.8-3.83.8-3.83.83.8-4.03.93.7-1.7-2.9
Times rat made contact with spout0.40.51.10.80.6-0.70.7-0.70.7-0.7-0.70.6-0.70.70.70.7-0.70.7-0.70.6-0.70.70.7-1.01.10.9-0.1-0.8
Lifetime Intake0.40.40.8-0.7-0.70.6-0.60.6-0.60.60.6-0.50.6-0.6-0.6-0.60.5-0.60.6-0.50.6-0.6-0.70.9-0.7-0.90.00.8
Liver weight, left0.10.21.60.40.1-0.20.2-0.20.2-0.2-0.20.1-0.20.20.20.2-0.20.3-0.20.0-0.20.20.40.20.3-0.40.91.3
Liver weight, right1.11.92.61.61.4-1.51.5-1.41.4-1.4-1.41.4-1.41.41.41.4-1.41.5-1.41.3-1.41.41.4-1.21.41.0-0.8-0.6
Locomotor activity5.79.011.72.93.1-3.13.1-3.13.1-3.1-3.13.4-3.13.13.13.1-3.23.1-3.13.4-3.23.13.1-2.72.82.5-1.4-1.6
Locomotor testing distance5.38.912.33.03.2-3.23.1-3.13.1-3.1-3.13.5-3.13.13.13.2-3.23.1-3.23.5-3.23.13.1-2.52.52.2-1.5-1.0
Locomotor testing rearing0.20.40.80.40.6-0.60.6-0.60.6-0.6-0.60.9-0.60.60.60.7-0.70.6-0.70.9-0.70.70.6-0.30.10.40.50.7
Locomotion in novel chamber0.20.20.4-0.4-0.50.5-0.50.5-0.50.50.5-0.30.5-0.4-0.4-0.50.4-0.50.5-0.40.5-0.4-0.5-0.3-0.20.6-0.0-0.3
Locomotion in novel chamber post-restriction0.81.02.01.01.0-1.01.0-1.01.0-1.0-1.01.1-1.01.01.01.0-1.01.0-1.01.0-1.01.01.0-1.31.11.4-0.5-0.9
Fecal boli incidents, locomotor time 10.50.51.40.70.7-0.70.7-0.70.7-0.7-0.70.7-0.70.70.70.7-0.70.7-0.70.6-0.70.70.7-1.10.61.2-0.3-0.9
Change in fecal boli incidents, locomotor task0.00.00.40.30.1-0.10.1-0.10.1-0.1-0.10.0-0.10.10.10.1-0.10.1-0.10.2-0.20.10.2-0.50.10.60.10.2
Time >=10cm from walls, locomotor time 10.10.10.3-0.2-0.30.3-0.30.3-0.30.40.3-0.40.3-0.3-0.4-0.30.4-0.30.4-0.50.3-0.4-0.30.5-0.3-0.50.30.6
Bouts of movement, locomotor time 10.00.00.10.20.1-0.10.1-0.10.1-0.1-0.10.0-0.10.10.10.1-0.10.1-0.10.0-0.10.10.1-0.30.10.30.20.1
Total resting periods, locomotor time 10.00.00.20.20.1-0.10.1-0.10.1-0.1-0.10.0-0.10.10.10.1-0.10.1-0.1-0.0-0.10.10.0-0.30.10.40.10.3
Rest time, locomotor task time 10.50.61.0-0.5-0.80.8-0.80.8-0.80.80.8-0.90.8-0.8-0.8-0.80.8-0.80.8-1.00.8-0.8-0.80.4-1.0-0.10.60.9
Distance moved, locomotor task time 11.71.92.41.41.4-1.41.4-1.41.4-1.4-1.41.5-1.41.41.41.4-1.41.4-1.41.5-1.41.41.3-1.31.61.2-0.9-1.3
Vertical activity count, locomotor time 10.80.91.30.90.9-0.91.0-0.90.9-0.9-0.91.0-0.90.90.90.9-0.90.9-0.91.0-0.90.90.9-1.11.21.0-0.6-0.7
Time >=10cm from walls, locomotor time 21.51.61.91.41.3-1.31.3-1.31.3-1.3-1.31.4-1.31.31.31.3-1.31.3-1.31.3-1.31.31.3-1.21.21.1-0.6-0.6
Bouts of movement, locomotor time 20.00.00.20.00.1-0.10.1-0.10.1-0.1-0.10.2-0.10.10.10.1-0.10.1-0.10.2-0.10.10.1-0.0-0.20.1-0.2-0.4
Total resting periods, locomotor time 20.00.00.3-0.3-0.20.2-0.20.2-0.20.20.2-0.10.2-0.2-0.2-0.20.1-0.20.20.00.2-0.2-0.20.3-0.5-0.1-0.1-0.2
Rest time, locomotor task time 20.00.00.2-0.1-0.10.2-0.20.2-0.20.20.2-0.20.2-0.2-0.2-0.20.2-0.20.20.00.2-0.2-0.2-0.1-0.40.30.30.2
Distance moved, locomotor task time 20.91.12.01.11.1-1.11.1-1.11.1-1.1-1.11.0-1.11.11.01.0-1.01.1-1.00.6-1.01.01.0-0.91.40.6-0.7-1.1
Vertical activity count, locomotor time 20.10.10.20.20.2-0.30.3-0.30.3-0.3-0.30.3-0.30.30.30.3-0.20.3-0.2-0.0-0.20.20.2-0.10.5-0.1-0.5-0.2
Light reinforcement 10.61.21.51.21.1-1.11.1-1.11.1-1.1-1.11.1-1.11.11.11.1-1.11.1-1.11.2-1.11.11.2-1.01.00.9-0.8-1.0
Light reinforcement 20.10.20.8-0.4-0.10.3-0.30.3-0.30.30.3-0.20.3-0.3-0.3-0.30.4-0.30.4-0.30.3-0.4-0.30.7-0.5-0.9-0.9-0.0
Bone: marrow area0.10.20.30.40.5-0.40.4-0.50.5-0.5-0.50.5-0.50.50.50.5-0.50.5-0.50.5-0.50.50.5-0.00.3-0.10.20.5
Bone: maximum diameter0.40.71.0-1.0-0.80.9-0.90.9-0.90.90.9-0.80.9-0.9-0.9-0.90.9-0.90.9-0.80.9-0.9-0.90.6-0.7-0.40.1-0.4
Bone: maximum force0.71.21.41.11.2-1.11.1-1.11.1-1.1-1.11.1-1.11.11.11.1-1.11.1-1.11.1-1.11.11.1-1.11.21.1-0.3-1.2
Bone: maximum moment0.81.41.81.21.3-1.21.2-1.21.2-1.2-1.21.2-1.21.21.21.2-1.21.2-1.21.2-1.21.21.2-1.31.21.2-0.4-1.3
Mean time between licks in bursts1.01.41.9-1.3-1.11.2-1.31.3-1.31.31.3-1.11.3-1.3-1.3-1.31.2-1.31.2-1.11.3-1.3-1.41.2-1.3-1.10.10.7
Mean num. licks in bursts0.50.61.10.80.8-0.90.9-0.90.8-0.8-0.90.8-0.80.90.90.8-0.80.8-0.80.8-0.80.80.8-0.51.00.2-0.7-0.4
Cd content in liver2.32.53.81.71.5-1.61.6-1.61.6-1.6-1.61.5-1.61.61.61.6-1.61.6-1.61.5-1.71.61.7-1.91.81.90.9-0.7
Co content in liver0.00.00.1-0.10.2-0.10.1-0.10.1-0.1-0.10.2-0.10.10.10.1-0.10.1-0.10.2-0.10.10.10.3-0.1-0.40.2-0.2
Cu content in liver3.94.75.72.42.2-2.22.2-2.22.2-2.2-2.22.2-2.22.22.22.2-2.32.2-2.32.2-2.32.32.2-2.32.22.2-0.6-0.7
Fe content in liver1.72.13.71.61.2-1.31.4-1.41.4-1.4-1.41.2-1.41.41.41.4-1.41.4-1.41.2-1.51.41.5-1.81.71.91.6-0.4
K content in liver0.90.82.41.00.9-0.90.9-0.90.9-0.9-0.91.0-0.90.90.90.8-0.90.8-0.81.0-0.80.80.8-1.00.80.9-1.5-0.9
Mg content in liver0.10.13.00.00.2-0.10.1-0.10.0-0.0-0.00.3-0.00.00.00.0-0.0-0.0-0.00.30.00.0-0.1-0.0-0.2-0.0-1.7-0.5
Mn content in liver0.70.83.40.81.0-0.90.9-0.90.9-0.9-0.91.1-0.90.90.90.9-0.90.8-0.91.1-0.90.90.7-0.30.7-0.1-1.8-0.2
Na content in liver0.30.41.10.70.4-0.60.6-0.60.6-0.6-0.60.4-0.60.60.60.6-0.60.6-0.60.4-0.60.60.7-0.40.80.31.00.4
Rb content in liver1.21.56.61.31.0-1.01.1-1.11.1-1.1-1.10.9-1.11.11.11.2-1.11.2-1.20.9-1.21.21.4-1.21.21.32.60.1
Se content in liver0.10.10.40.30.1-0.20.2-0.20.2-0.2-0.20.0-0.10.20.10.1-0.10.2-0.10.0-0.10.10.2-0.50.30.5-0.6-0.6
Sr content in liver0.20.24.3-0.00.3-0.20.1-0.10.1-0.1-0.10.3-0.10.10.10.1-0.10.0-0.00.3-0.00.0-0.10.0-0.1-0.1-2.1-0.6
Zn content in liver4.55.05.82.32.4-2.32.3-2.32.3-2.3-2.32.4-2.32.32.32.3-2.32.2-2.32.4-2.22.32.1-2.42.22.3-1.7-1.3
Bone: minimum diameter0.30.60.9-1.0-0.70.8-0.80.8-0.80.80.8-0.70.8-0.8-0.8-0.80.8-0.80.8-0.70.8-0.8-0.80.9-0.9-0.90.00.2
Time in familiar zone, hab. session 11.41.33.3-1.2-1.21.2-1.21.2-1.11.11.1-1.21.1-1.1-1.1-1.11.1-1.11.1-1.21.1-1.1-1.01.0-1.2-0.71.80.8
Time in novel zone, hab. session 10.60.60.90.80.8-0.80.8-0.80.8-0.8-0.80.7-0.80.80.80.7-0.70.8-0.70.7-0.70.70.8-0.81.00.6-0.9-0.8
Total zone transitions, hab. session 10.60.94.30.71.1-1.00.9-0.90.9-0.9-0.91.1-0.90.90.90.9-0.90.9-0.91.1-0.90.90.7-0.40.70.1-2.1-0.5
Total locomotion distance, hab. session 10.30.41.50.60.6-0.60.6-0.60.6-0.6-0.60.6-0.60.60.60.6-0.60.6-0.60.6-0.50.60.5-0.50.50.3-1.2-0.5
Locomotion velocity, hab. session 10.30.41.50.60.6-0.60.6-0.60.6-0.6-0.60.7-0.60.60.60.6-0.60.6-0.60.7-0.60.60.5-0.40.60.2-1.2-0.3
Time in familiar zone, hab. session 20.40.40.7-0.8-0.70.7-0.70.7-0.70.70.7-0.60.7-0.7-0.7-0.70.7-0.70.7-0.60.7-0.7-0.80.5-0.8-0.20.50.1
Time in novel zone, hab. session 20.00.00.20.10.1-0.20.2-0.20.2-0.2-0.20.1-0.20.20.20.2-0.20.2-0.20.1-0.20.20.20.10.3-0.30.20.4
Total zone transitions, hab. session 20.20.34.40.10.5-0.30.3-0.30.3-0.3-0.30.5-0.30.30.30.3-0.30.2-0.20.5-0.20.20.0-0.10.0-0.0-2.1-0.7
Total locomotion distance, hab. session 20.30.42.20.60.7-0.60.6-0.60.6-0.6-0.60.7-0.60.60.60.6-0.60.5-0.60.7-0.50.50.4-0.60.50.5-1.5-0.7
Locomotion velocity, hab. session 20.20.32.10.60.5-0.50.5-0.50.5-0.5-0.50.5-0.50.50.50.4-0.40.4-0.40.5-0.40.40.3-0.50.40.4-1.5-0.6
Novel to familiar place preference ratio0.80.81.00.91.0-1.00.9-0.90.9-0.9-0.90.9-0.90.90.90.9-1.00.9-0.90.9-0.90.90.9-0.20.9-0.2-0.50.9
Novelty place preference0.80.81.00.91.0-0.90.9-0.90.9-0.9-0.90.9-0.90.90.90.9-0.90.9-0.90.9-0.90.90.9-0.21.0-0.3-0.41.0
Time in novel zone, NPP test1.01.01.21.01.1-1.11.1-1.11.1-1.1-1.11.0-1.11.11.11.1-1.11.1-1.11.0-1.11.11.0-0.41.1-0.0-0.30.8
Total zone transitions, NPP test2.43.512.81.62.1-1.91.9-1.81.8-1.8-1.82.2-1.81.81.81.8-1.81.7-1.82.2-1.81.81.5-1.31.50.9-3.6-1.2
Total locomotion distance, NPP test1.11.43.81.21.2-1.21.2-1.21.2-1.2-1.21.3-1.21.21.21.1-1.21.1-1.11.3-1.11.11.0-1.21.11.1-2.0-1.1
Locomotion velocity, NPP test1.11.64.41.31.3-1.31.2-1.21.2-1.2-1.21.3-1.21.21.21.2-1.21.2-1.21.3-1.21.21.0-1.21.21.0-2.1-1.0
Intraocular pressure1.01.41.91.41.0-1.21.2-1.21.2-1.2-1.21.2-1.21.21.21.2-1.21.3-1.21.1-1.31.21.3-1.31.31.31.10.1
Delta distance traveled before/after self-admin0.20.20.4-0.5-0.30.4-0.40.4-0.40.40.4-0.30.4-0.4-0.5-0.40.5-0.40.4-0.30.4-0.5-0.40.6-0.5-0.6-0.00.1
Delta ambulatory time before/after self-admin0.20.20.40.40.6-0.50.6-0.50.6-0.5-0.50.6-0.50.50.50.5-0.50.5-0.50.6-0.50.50.5-0.20.30.1-0.2-0.4
Parametrial fat weight1.02.02.51.61.5-1.51.5-1.51.5-1.5-1.51.4-1.51.51.51.5-1.41.5-1.41.4-1.41.41.5-1.21.41.0-1.0-0.9
Pavlov. Cond. lever latency4.96.27.72.72.6-2.62.6-2.62.6-2.6-2.62.4-2.62.62.62.6-2.62.7-2.72.4-2.72.72.8-2.32.81.90.3-0.8
Pavlov. Cond. magazine entry latency6.17.89.7-3.1-2.93.0-3.03.0-3.03.03.0-2.73.0-3.0-3.0-3.02.9-3.03.0-2.73.0-3.0-3.02.6-3.0-2.20.60.9
Pavlov. Cond. change in total contacts1.61.72.0-1.4-1.41.4-1.41.4-1.41.41.4-1.31.4-1.4-1.4-1.41.4-1.41.4-1.31.4-1.4-1.41.0-1.4-0.70.80.6
Pavlov. Cond. index score6.07.79.3-3.0-2.92.9-2.92.9-2.92.92.9-2.72.9-2.9-2.9-2.92.9-3.02.9-2.72.9-2.9-3.02.5-3.0-2.00.50.9
Pavlov. Cond. latency score5.97.59.1-3.0-2.82.9-2.92.9-2.92.92.9-2.72.9-2.9-2.9-2.92.9-2.92.9-2.72.9-2.9-3.02.5-3.0-2.10.31.0
Pavlov. Cond. lever contacts2.83.34.4-2.0-1.91.9-1.91.9-1.92.01.9-1.71.9-1.9-1.9-2.01.9-2.02.0-1.72.0-2.0-2.11.6-2.0-1.3-0.50.5
Pavlov. Cond. magazine entry number7.18.810.63.33.1-3.13.1-3.13.1-3.1-3.12.9-3.13.13.13.1-3.13.2-3.12.9-3.13.13.2-2.73.12.3-0.9-1.2
Pavlov. Cond. intertrial magazine entries0.40.40.60.70.7-0.70.7-0.70.7-0.7-0.70.7-0.70.70.70.7-0.70.7-0.70.7-0.70.70.8-0.40.60.30.1-0.1
Pavlov. Cond. lever-magazine prob. diff.5.36.68.1-2.8-2.72.7-2.72.7-2.82.82.7-2.52.7-2.7-2.7-2.72.7-2.82.7-2.52.8-2.7-2.92.2-2.8-1.70.40.7
Pavlov. Cond. response bias6.68.09.6-3.1-2.93.0-3.03.0-3.03.03.0-2.83.0-3.0-3.0-3.03.0-3.03.0-2.83.0-3.0-3.12.5-3.0-2.00.50.9
Pavlov. Cond. lever latency0.50.71.9-0.7-1.00.8-0.80.8-0.80.80.8-1.00.8-0.8-0.8-0.80.8-0.70.8-1.00.8-0.8-0.60.8-0.7-0.71.40.7
Pavlov. Cond. magazine entry latency0.20.21.8-0.4-0.10.3-0.30.3-0.30.30.3-0.10.3-0.3-0.3-0.30.3-0.40.3-0.10.3-0.3-0.60.2-0.6-0.1-1.4-0.5
Pavlov. Cond. change in total contacts2.63.64.51.82.1-1.91.9-1.91.9-1.9-1.92.1-1.91.91.91.9-1.91.8-1.92.1-1.91.91.6-2.01.61.9-1.9-1.6
Pavlov. Cond. index score0.20.32.60.30.5-0.40.3-0.30.3-0.3-0.30.5-0.30.30.30.3-0.40.3-0.30.5-0.30.30.1-0.50.10.6-1.6-0.9
Pavlov. Cond. latency score0.20.22.50.20.5-0.30.3-0.30.3-0.3-0.30.5-0.30.30.30.2-0.30.2-0.20.5-0.20.20.0-0.40.00.5-1.6-0.8
Pavlov. Cond. lever contacts1.11.52.81.21.4-1.21.2-1.21.2-1.2-1.21.3-1.21.21.21.2-1.21.2-1.21.3-1.21.21.0-1.11.01.0-1.7-0.8
Pavlov. Cond. magazine entry number0.30.41.10.70.4-0.60.6-0.60.6-0.6-0.60.4-0.60.60.60.6-0.60.7-0.60.4-0.60.60.9-0.50.80.31.00.2
Pavlov. Cond. intertrial magazine entries0.50.73.1-0.8-0.80.7-0.70.7-0.70.70.7-0.80.7-0.7-0.7-0.70.7-0.70.7-0.80.7-0.7-0.50.9-0.6-0.91.81.2
Pavlov. Cond. lever-magazine prob. diff.0.20.33.10.20.5-0.30.3-0.30.3-0.3-0.30.5-0.30.30.30.3-0.30.2-0.30.5-0.30.30.0-0.50.00.5-1.7-0.9
Pavlov. Cond. response bias0.20.22.70.20.5-0.30.3-0.30.3-0.3-0.30.5-0.30.30.30.3-0.30.2-0.30.5-0.30.30.0-0.40.10.4-1.6-0.6
Time in closed arm before self-admin1.71.92.51.21.4-1.41.4-1.41.4-1.4-1.41.6-1.41.41.41.4-1.51.4-1.41.3-1.41.51.4-1.31.31.2-0.5-1.4
Time in closed arm after self-admin0.10.10.60.30.1-0.10.1-0.10.1-0.1-0.10.1-0.10.10.10.1-0.10.1-0.10.0-0.10.20.1-0.60.20.8-0.1-0.2
Time in open arm before self-admin1.21.32.1-1.0-1.31.2-1.11.2-1.11.21.2-1.41.2-1.2-1.2-1.21.2-1.21.2-1.21.2-1.2-1.20.9-0.9-0.90.41.1
Time in open arm after self-admin0.30.42.9-0.8-0.50.4-0.40.4-0.40.40.4-0.30.4-0.4-0.4-0.40.4-0.40.4-0.40.4-0.4-0.41.3-0.5-1.70.30.5
Bone: periosteal estimation0.00.00.10.00.2-0.10.1-0.10.1-0.1-0.10.2-0.10.10.10.1-0.20.1-0.10.2-0.10.10.1-0.00.1-0.0-0.0-0.3
Bone: periosteal perimeter1.11.92.5-1.6-1.41.4-1.41.4-1.41.41.4-1.41.4-1.4-1.4-1.41.4-1.41.4-1.41.4-1.4-1.41.4-1.3-1.30.50.4
Bone: post-yield work0.00.00.10.10.3-0.20.2-0.20.2-0.2-0.20.2-0.20.20.20.2-0.20.2-0.20.2-0.20.20.2-0.00.2-0.0-0.3-0.1
Progressive ratio test 1 active lever presses0.00.00.6-0.1-0.20.1-0.10.1-0.10.00.0-0.00.0-0.0-0.0-0.00.0-0.10.0-0.00.0-0.0-0.10.4-0.2-0.4-0.00.8
Progressive ratio test 1 breakpoint0.10.10.6-0.2-0.30.2-0.20.2-0.20.20.2-0.10.2-0.1-0.1-0.20.1-0.20.1-0.20.1-0.1-0.20.4-0.3-0.50.00.8
Progressive ratio test 1 inactive lever presses0.30.40.6-0.7-0.70.7-0.70.7-0.70.60.6-0.70.6-0.6-0.6-0.60.6-0.70.6-0.80.6-0.6-0.50.3-0.8-0.10.20.2
Progressive ratio test 2 active lever presses0.91.01.5-1.1-1.11.0-1.01.0-1.01.01.0-0.91.0-1.0-1.0-1.01.0-1.01.0-0.81.0-1.0-1.01.2-1.1-1.20.31.0
Progressive ratio test 2 breakpoint0.70.81.1-1.0-1.10.9-0.90.9-0.90.90.9-0.80.9-0.9-0.9-0.90.9-0.90.9-0.80.9-0.9-1.01.1-0.9-1.00.20.8
Progressive ratio test 2 inactive lever presses1.92.23.0-1.7-1.61.6-1.61.6-1.61.61.5-1.31.5-1.5-1.5-1.51.5-1.61.5-1.41.5-1.5-1.61.4-1.7-1.20.30.3
Incentive Sensitization - Responses1.71.72.0-1.4-1.41.3-1.31.3-1.31.41.4-1.31.4-1.4-1.4-1.41.4-1.41.4-1.31.4-1.4-1.41.3-1.3-1.20.40.7
Incentive Sensitization - Breakpoint1.61.61.9-1.3-1.41.3-1.31.3-1.31.31.3-1.31.3-1.3-1.3-1.31.3-1.31.3-1.21.3-1.3-1.41.3-1.3-1.20.40.7
Sum of active levers in priming session hrs 5-60.40.40.60.70.6-0.70.7-0.70.7-0.7-0.70.4-0.70.70.70.7-0.70.7-0.70.3-0.70.70.7-0.40.80.2-0.1-0.1
Progressive ratio3.43.94.82.12.1-2.02.0-2.02.0-2.0-2.02.0-2.02.02.02.0-2.12.0-2.02.0-2.02.12.0-2.22.22.1-0.8-1.0
Food seeking constrained by brief footshock0.70.91.6-1.1-1.00.9-1.01.0-1.01.00.9-0.81.0-0.9-0.9-1.00.9-1.01.0-0.91.0-1.0-1.01.2-0.7-1.3-0.10.2
Seeking ratio, punishment vs. effort5.26.47.7-2.8-2.72.6-2.62.6-2.62.62.6-2.52.6-2.6-2.6-2.62.6-2.62.6-2.62.6-2.6-2.62.7-2.6-2.60.60.9
Retroperitoneal fat weight0.61.92.21.51.5-1.51.5-1.41.4-1.4-1.41.3-1.41.41.41.4-1.41.4-1.41.3-1.41.41.5-1.31.41.0-0.9-1.2
Reaction time number correct0.30.50.8-0.9-0.70.7-0.70.7-0.70.70.7-0.70.7-0.7-0.7-0.70.6-0.70.6-0.70.6-0.7-0.60.9-0.6-0.90.70.6
Reaction time mean minus median0.10.10.60.30.2-0.30.2-0.20.2-0.2-0.20.4-0.20.20.20.2-0.20.2-0.20.4-0.20.20.2-0.30.20.3-0.8-0.1
Reaction time mean minus median AUC0.20.30.50.70.5-0.50.5-0.50.5-0.5-0.50.6-0.50.50.50.5-0.50.5-0.50.7-0.50.50.5-0.60.40.7-0.6-0.0
Reaction time num false alarms0.30.41.1-0.7-0.70.6-0.60.6-0.60.60.6-0.60.6-0.6-0.6-0.60.6-0.60.6-0.50.6-0.6-0.61.0-0.7-1.00.90.5
Reaction time num false alarms AUC0.10.20.9-0.3-0.30.3-0.20.3-0.20.30.3-0.30.3-0.3-0.3-0.30.3-0.20.3-0.30.2-0.3-0.20.8-0.3-0.90.80.4
Reaction time trials correct on left0.30.50.8-0.9-0.70.7-0.70.7-0.70.70.7-0.70.7-0.7-0.7-0.70.6-0.70.6-0.70.6-0.7-0.60.9-0.6-0.90.70.6
Reaction time trials on left0.40.50.9-0.9-0.70.7-0.70.7-0.70.70.7-0.70.7-0.7-0.7-0.70.7-0.70.7-0.70.7-0.7-0.70.9-0.7-0.90.70.6
Reaction time mean0.00.00.40.2-0.1-0.10.1-0.10.1-0.1-0.10.2-0.10.10.10.1-0.10.1-0.10.2-0.10.10.1-0.00.00.00.20.7
Reaction time mean AUC0.00.00.70.1-0.2-0.00.0-0.00.0-0.0-0.00.1-0.00.00.00.0-0.00.0-0.00.1-0.00.00.10.1-0.0-0.20.30.8
Median of all reaction times0.00.00.70.1-0.1-0.10.1-0.10.1-0.1-0.10.1-0.10.10.10.1-0.10.1-0.10.2-0.10.10.10.10.0-0.10.50.8
Reaction time omissions0.30.52.9-0.4-0.90.6-0.60.6-0.60.60.6-0.70.6-0.6-0.6-0.60.6-0.50.6-0.70.6-0.6-0.40.5-0.3-0.41.71.0
Reaction time false alarm rate0.00.00.3-0.1-0.20.2-0.10.2-0.10.20.2-0.20.2-0.2-0.2-0.20.2-0.10.2-0.20.1-0.2-0.10.4-0.2-0.50.60.1
Reaction time premature initiation rate2.02.63.31.81.6-1.71.7-1.71.7-1.7-1.71.6-1.71.71.61.7-1.61.7-1.71.7-1.71.61.8-1.61.71.5-0.6-0.9
Reaction time premature initiations0.91.21.81.21.1-1.21.2-1.21.2-1.2-1.21.1-1.21.21.11.2-1.11.2-1.21.2-1.21.11.3-1.01.20.8-0.3-0.6
Std. dev. reaction times0.10.10.40.40.2-0.40.4-0.40.4-0.4-0.40.6-0.40.40.40.4-0.40.3-0.40.6-0.40.40.4-0.20.30.1-0.20.6
Reaction time trials completed0.40.50.9-0.9-0.70.7-0.70.7-0.70.70.7-0.70.7-0.7-0.7-0.70.7-0.70.7-0.70.7-0.7-0.70.9-0.7-0.90.70.6
Reaction time trials AUC0.50.71.1-1.0-0.80.8-0.80.8-0.80.80.8-0.80.8-0.8-0.8-0.80.8-0.80.8-0.80.8-0.8-0.81.0-0.8-1.00.80.7
Run reversals in cocaine runway, females1.81.72.2-1.4-1.51.3-1.31.3-1.31.31.3-1.51.3-1.3-1.3-1.31.4-1.31.4-1.41.4-1.4-1.31.3-1.2-1.30.60.4
Run reversals in cocaine runway, males0.60.61.20.80.8-0.80.8-0.80.8-0.7-0.70.8-0.70.70.70.7-0.70.7-0.70.8-0.70.70.8-1.10.91.1-0.4-1.1
Latency to leave start box in cocaine runway0.40.51.60.80.8-0.60.6-0.60.6-0.6-0.60.6-0.60.60.60.6-0.60.6-0.60.6-0.60.60.6-1.10.81.3-0.5-0.8
Latency to leave start box in cocaine runway, F1.51.73.31.21.4-1.31.2-1.21.2-1.2-1.21.3-1.21.21.21.2-1.21.2-1.21.3-1.21.21.2-1.61.31.7-0.9-1.8
Latency to leave start box in cocaine runway, M0.40.31.1-0.2-0.50.6-0.60.6-0.60.60.6-0.60.6-0.6-0.6-0.60.6-0.60.6-0.60.6-0.6-0.60.2-0.5-0.10.31.1
Std. dev. time between licks in bursts3.54.25.7-2.4-2.02.2-2.22.2-2.22.22.2-1.92.2-2.2-2.2-2.22.1-2.22.2-1.92.2-2.2-2.31.9-2.4-1.50.60.8
Total sessions with >9 infusions0.10.10.3-0.1-0.30.2-0.20.2-0.20.20.2-0.20.2-0.2-0.2-0.20.2-0.20.20.00.2-0.2-0.1-0.3-0.40.60.1-0.0
Short access day 1 total inactive lever presses3.33.65.5-2.0-2.02.0-2.02.0-2.02.02.0-1.82.0-2.0-2.0-2.01.9-2.02.0-1.82.0-2.0-2.01.8-2.3-1.40.61.3
Short access day 10 total inactive lever presses0.00.10.7-0.00.10.1-0.10.1-0.10.10.1-0.10.1-0.1-0.1-0.10.1-0.10.1-0.30.1-0.10.0-0.3-0.10.50.0-0.8
Short access day 1 total infusions0.80.81.3-0.8-1.01.0-1.01.0-1.01.01.0-1.01.0-1.0-1.0-1.01.0-1.01.0-1.01.0-1.0-0.90.6-1.1-0.40.40.7
Short access day 10 total infusions0.10.10.5-0.3-0.30.2-0.20.2-0.20.20.2-0.00.2-0.2-0.2-0.20.1-0.20.2-0.10.2-0.2-0.30.5-0.3-0.5-0.20.7
Short access total infusions0.50.61.1-0.8-0.80.7-0.70.7-0.70.70.7-0.70.7-0.7-0.7-0.70.7-0.80.7-0.70.7-0.7-0.80.9-0.9-0.90.11.1
Short access day 1 locomotion0.00.00.2-0.2-0.30.2-0.20.2-0.20.20.2-0.00.2-0.2-0.2-0.20.2-0.20.2-0.10.2-0.2-0.30.0-0.20.1-0.10.5
Short access day 10 total locomotion0.00.00.30.10.1-0.20.2-0.20.2-0.2-0.20.1-0.20.20.20.2-0.20.2-0.20.2-0.20.20.0-0.20.20.1-0.20.5
Short access total locomotion0.00.00.8-0.1-0.20.1-0.10.1-0.10.10.1-0.00.1-0.1-0.1-0.10.1-0.10.10.00.1-0.1-0.30.1-0.1-0.0-0.20.9
One hour access (0.3 mA shock)0.20.21.4-0.6-0.50.3-0.40.4-0.40.30.3-0.10.3-0.3-0.3-0.30.3-0.40.3-0.10.3-0.3-0.41.0-0.5-1.2-0.01.1
Compulsive drug intake0.10.11.0-0.1-0.00.1-0.10.1-0.10.10.1-0.10.1-0.1-0.1-0.10.1-0.10.1-0.20.1-0.10.00.5-0.1-0.70.21.0
One hour access (shock baseline)0.10.10.3-0.5-0.40.2-0.20.2-0.20.20.2-0.10.2-0.2-0.2-0.20.1-0.20.2-0.00.2-0.2-0.40.6-0.4-0.6-0.20.3
Social response proportion0.40.41.10.70.6-0.70.7-0.70.7-0.7-0.70.6-0.70.70.70.7-0.60.7-0.70.5-0.70.70.8-0.51.00.30.5-0.4
Social responses0.30.40.60.60.7-0.70.7-0.70.7-0.7-0.70.6-0.70.70.70.7-0.70.7-0.70.6-0.70.70.7-0.40.80.2-0.5-0.4
Social time0.50.60.8-0.9-0.80.8-0.80.8-0.80.80.8-0.90.8-0.8-0.8-0.80.9-0.80.8-0.90.8-0.8-0.70.9-0.7-0.90.1-0.4
Soleus weight3.911.413.53.53.7-3.53.5-3.53.4-3.4-3.43.6-3.43.43.43.4-3.53.4-3.43.6-3.43.43.2-3.53.23.3-2.6-2.5
Bone: stiffness0.10.20.30.50.4-0.40.4-0.40.5-0.5-0.50.4-0.50.50.50.5-0.40.5-0.50.4-0.50.50.5-0.40.60.30.4-0.3
Tibialis anterior weight0.00.10.20.20.2-0.20.2-0.20.2-0.2-0.20.2-0.20.20.20.2-0.20.1-0.20.2-0.10.20.1-0.40.10.4-0.5-0.5
Time to tail flick, vehicle, before self-admin2.12.14.41.81.5-1.41.4-1.41.4-1.4-1.41.4-1.41.41.41.4-1.41.4-1.41.3-1.41.51.4-2.01.32.1-0.2-1.1
Time to tail flick, vehicle, after self-admin0.50.61.40.50.9-0.80.8-0.80.8-0.8-0.80.4-0.80.80.80.7-0.70.8-0.70.5-0.70.70.7-0.70.80.5-0.6-1.2
Time to tail flick, test, before self-admin0.10.10.30.30.2-0.20.2-0.20.2-0.2-0.2-0.1-0.20.20.10.1-0.10.2-0.1-0.0-0.10.10.20.10.5-0.4-0.30.5
Time to tail flick, test, after self-admin0.10.10.3-0.3-0.50.4-0.40.4-0.40.40.4-0.60.4-0.4-0.4-0.40.4-0.40.4-0.60.4-0.4-0.50.1-0.30.00.10.2
Delta time to tail flick, vehicle, before/after SA0.50.51.0-1.0-0.60.7-0.70.7-0.70.70.7-0.80.7-0.7-0.7-0.70.7-0.70.7-0.70.7-0.7-0.70.9-0.6-0.9-0.20.1
Delta time to tail flick, test, before/after SA0.30.20.5-0.5-0.60.5-0.60.5-0.50.50.5-0.50.5-0.5-0.5-0.50.5-0.50.5-0.50.5-0.5-0.60.2-0.7-0.00.30.3
Tibia length6.919.322.74.44.8-4.64.5-4.54.5-4.5-4.54.7-4.54.54.54.5-4.54.4-4.44.7-4.44.44.2-4.24.13.8-4.2-3.5
Ambulatory time before self-admin0.10.10.2-0.4-0.10.2-0.30.2-0.20.20.2-0.30.2-0.2-0.2-0.20.2-0.20.2-0.20.2-0.2-0.20.3-0.5-0.20.3-0.1
Ambulatory time after self-admin0.10.10.4-0.40.10.1-0.10.1-0.10.10.1-0.30.1-0.1-0.1-0.10.1-0.10.1-0.10.1-0.1-0.00.5-0.4-0.50.1-0.7
Bone: tissue strength3.13.03.61.71.8-1.81.8-1.81.8-1.8-1.81.8-1.81.81.81.8-1.81.8-1.81.8-1.81.81.7-1.91.71.9-0.6-1.6
Total heroin consumption1.11.31.61.21.3-1.21.2-1.21.2-1.2-1.20.9-1.21.21.21.2-1.21.2-1.21.1-1.21.21.2-1.21.01.2-0.3-0.8
Bone: trabecular number0.71.03.1-1.0-0.90.9-0.90.9-0.90.90.9-0.80.9-0.9-0.9-0.90.9-0.90.9-0.80.9-0.9-1.01.5-1.0-1.8-0.11.4
Bone: trabecular spacing1.51.93.81.51.3-1.31.3-1.31.3-1.3-1.31.2-1.31.31.31.3-1.31.4-1.31.2-1.31.31.4-1.81.31.9-0.0-1.8
Bone: trabecular thickness0.10.10.90.20.2-0.20.2-0.20.2-0.1-0.20.2-0.10.10.10.1-0.10.1-0.10.2-0.10.10.10.10.2-0.3-1.00.2
Bone: trabecular tissue density0.20.30.40.60.6-0.60.6-0.60.6-0.6-0.60.5-0.60.60.60.6-0.60.6-0.60.5-0.60.60.6-0.40.60.3-0.4-0.4
Water consumed over 24 hours0.00.10.7-0.1-0.00.1-0.10.1-0.10.10.1-0.00.1-0.1-0.1-0.10.1-0.10.1-0.00.1-0.1-0.2-0.30.10.4-0.5-0.8
Number of responses in last shaping day0.70.71.2-1.0-0.90.9-0.90.9-0.90.90.9-0.80.9-0.9-0.9-0.90.9-0.90.9-0.90.9-0.8-0.70.9-1.1-0.70.30.2