Hub : Genes

Ccdc12

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Brain intron excision ratio chr8_119547056_119561689 0.05 0.04 3.9e-05 0.05 0.05 0.05 0.05 1.5e-05 2.1e-05 2.2e-05 1.1e-05
2 Brain intron excision ratio chr8_119514247_119546989 0.04 0.04 2.8e-04 0.04 0.04 0.04 0.04 1.1e-04 1.5e-04 1.5e-04 9.9e-05
3 LHb gene expression Ccdc12 0.49 0.25 3.8e-06 0.11 0.15 0.16 0.15 1.6e-03 2.2e-04 1.1e-04 2.4e-04
4 NAcc intron excision ratio chr8_119513818_119513907 0.04 0.04 2.8e-05 0.03 0.03 0.03 0.03 2.2e-05 2.0e-05 1.5e-05 2.0e-05
5 Brain mRNA stability Ccdc12 0.17 0.12 2.6e-14 0.16 0.15 0.16 0.16 1.4e-14 6.2e-14 2.4e-14 8.4e-15
6 Brain gene expression Ccdc12 0.04 0.03 7.7e-04 0.03 0.02 0.02 0.02 1.3e-03 3.0e-03 3.4e-03 3.6e-03
7 Eye gene expression Ccdc12 0.28 0.22 7.7e-03 0.1 0.08 0.06 0.07 1.3e-02 2.5e-02 4.3e-02 3.0e-02
8 PL gene expression Ccdc12 0.07 0.1 6.9e-05 0.03 0.03 0.02 0.03 1.2e-04 1.7e-04 3.8e-03 1.1e-04
9 NAcc intron excision ratio chr8_119514247_119546989 0.01 0.01 1.0e-02 0.01 0.01 0 0.01 3.9e-02 8.9e-03 7.6e-02 3.1e-02
10 NAcc intron excision ratio chr8_119547056_119561689 0.01 0.01 6.6e-03 0.01 0.01 0.01 0.01 3.0e-02 5.7e-03 2.9e-02 3.2e-02
11 RMTg gene expression Ccdc12 0.27 0.18 4.3e-05 0.11 0.13 0.13 0.1 7.3e-04 2.4e-04 2.9e-04 1.0e-03
12 pVTA gene expression Ccdc12 0.29 0.16 0.0e+00 0.24 0.23 0.22 0.25 1.9e-19 9.0e-19 1.6e-17 7.4e-20
13 PL mRNA stability Ccdc12 0.04 0.04 1.8e-04 0.03 0.03 0.03 0.03 2.2e-04 1.4e-04 9.4e-04 4.9e-04
14 IC gene expression Ccdc12 0.15 0.12 3.0e-06 0.12 0.12 0.12 0.12 7.4e-06 6.5e-06 1.1e-05 7.6e-06
15 NAcc intron excision ratio chr8_119513818_119513981 0.04 0.04 3.9e-05 0.03 0.03 0.03 0.03 2.7e-05 2.6e-05 3.1e-05 3.5e-05
16 NAcc gene expression Ccdc12 0.05 0.04 1.3e-08 0.05 0.05 0.05 0.05 1.1e-08 1.1e-08 3.0e-08 2.0e-08
17 PL intron excision ratio chr8_119513818_119513907 0.02 0.02 8.7e-03 0.02 0.02 0.01 0.01 5.5e-03 5.9e-03 8.8e-03 7.2e-03
18 BLA gene expression Ccdc12 0.13 0.12 1.4e-05 0.09 0.08 0.09 0.08 1.2e-05 5.5e-05 1.9e-05 6.4e-05
19 IL gene expression Ccdc12 0.15 0.13 7.2e-03 0.06 0.06 0.05 0.05 1.7e-02 1.8e-02 2.0e-02 2.3e-02
20 OFC mRNA stability Ccdc12 0.16 0.13 4.5e-03 0.05 0.01 -0.01 0.03 2.2e-02 1.9e-01 7.6e-01 5.7e-02

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20
Bone: apparent density0.00.00.20.1-0.10.4-0.1-0.0-0.0-0.0-0.00.0-0.0-0.00.10.0-0.1-0.0-0.10.1-0.10.4-0.4
Area under the delay curve1.92.33.01.7-1.71.6-1.6-1.51.51.41.3-1.51.51.51.5-1.51.51.51.4-1.51.71.4-1.4
BMI with tail0.20.62.1-0.70.5-1.50.60.9-0.8-0.7-0.70.5-0.5-0.5-0.50.5-0.5-0.5-1.10.9-0.4-1.01.0
BMI without tail0.61.82.8-1.31.3-1.71.21.4-1.5-1.4-1.51.3-1.3-1.2-1.21.3-1.2-1.2-1.51.5-1.1-1.31.3
Body weight5.724.832.5-5.35.1-5.75.15.1-5.0-4.9-5.04.8-4.8-4.8-4.84.8-4.8-4.8-5.25.1-4.6-4.94.9
Weight adjusted by age0.00.00.1-0.30.3-0.30.20.1-0.1-0.0-0.00.0-0.0-0.0-0.10.0-0.0-0.0-0.10.0-0.1-0.20.2
Bone surface0.10.20.30.3-0.40.3-0.5-0.40.30.40.4-0.50.50.50.5-0.50.50.50.3-0.30.50.5-0.5
Bone volume0.00.10.20.2-0.20.3-0.2-0.20.20.20.2-0.20.20.20.3-0.20.20.20.1-0.10.20.5-0.5
Breakpoint value in progressive ratio session0.20.20.70.8-0.80.6-0.6-0.40.60.50.3-0.40.40.40.4-0.40.40.40.6-0.60.20.3-0.3
Number of licking bursts0.10.20.40.6-0.60.2-0.4-0.50.60.50.5-0.50.50.40.5-0.50.40.40.4-0.50.40.0-0.0
Context. condit. distance diff. score0.00.00.0-0.00.0-0.1-0.10.1-0.1-0.00.0-0.00.0-0.00.1-0.0-0.00.0-0.00.00.0-0.10.1
Locomotion velocity, session 10.10.10.30.3-0.30.5-0.3-0.20.30.30.3-0.30.30.30.2-0.30.30.30.1-0.10.20.6-0.6
Locomotion distance, session 10.81.01.6-1.11.1-0.91.01.1-1.1-1.1-1.11.0-1.0-1.0-1.01.0-0.9-1.0-1.31.3-0.9-0.40.4
Locomotion velocity, session 20.30.40.50.7-0.70.5-0.7-0.50.60.60.5-0.60.60.70.6-0.70.70.60.4-0.40.70.6-0.6
Locomotion distance, session 20.10.10.80.1-0.20.4-0.10.10.10.10.1-0.20.20.20.1-0.20.20.2-0.20.20.10.9-0.9
Locomotion velocity, session 30.10.10.3-0.30.2-0.20.10.4-0.5-0.6-0.50.3-0.3-0.3-0.20.3-0.3-0.3-0.50.5-0.10.2-0.2
Locomotion distance, session 30.90.91.51.0-1.10.9-1.1-0.80.80.80.7-0.90.91.01.1-1.01.01.00.7-0.71.01.2-1.2
Stereotopy head waving bouts, day 30.10.10.7-0.40.4-0.80.40.2-0.1-0.1-0.10.1-0.1-0.2-0.30.1-0.1-0.2-0.10.1-0.3-0.90.9
Stereotopy head waving duration, day 30.30.40.9-0.70.7-0.80.70.5-0.4-0.4-0.40.5-0.5-0.5-0.60.5-0.5-0.6-0.40.4-0.7-0.90.9
Locomotion velocity, session 70.40.40.8-0.90.9-0.40.70.7-0.8-0.7-0.60.6-0.7-0.7-0.30.7-0.7-0.7-0.70.7-0.6-0.00.0
Locomotion distance, session 70.50.61.20.7-0.70.9-0.8-0.60.60.60.7-0.70.70.71.1-0.70.70.70.6-0.60.71.1-1.1
Stereotopy head waving bouts, day 70.10.10.20.3-0.40.5-0.3-0.20.30.20.1-0.20.20.2-0.0-0.20.20.20.4-0.40.30.3-0.3
Stereotopy head waving duration, day 70.10.20.4-0.30.3-0.10.40.5-0.4-0.5-0.60.5-0.5-0.5-0.60.5-0.4-0.4-0.30.3-0.3-0.20.2
Locomotion velocity, session 80.20.30.7-0.50.4-0.60.30.7-0.6-0.6-0.70.5-0.5-0.5-0.40.5-0.5-0.5-0.80.8-0.4-0.20.2
Locomotion distance, session 80.20.30.7-0.50.5-0.20.30.7-0.7-0.6-0.60.4-0.4-0.4-0.30.4-0.4-0.4-0.80.8-0.40.4-0.4
Degree of sensitization distance1.41.52.1-1.41.5-1.11.41.2-1.2-1.1-1.01.2-1.2-1.2-1.11.2-1.3-1.3-1.11.1-1.3-1.11.1
Degree of sensitization stereotypy0.10.10.40.2-0.20.6-0.2-0.10.0-0.1-0.10.0-0.00.0-0.20.00.00.00.3-0.30.30.4-0.4
Conditioned locomotion3.74.26.22.1-2.12.5-2.1-2.21.92.02.0-2.02.02.01.9-2.02.02.02.1-2.01.92.3-2.3
Cocaine response after cond. corrected0.40.51.6-0.70.7-1.20.70.6-0.5-0.5-0.50.5-0.5-0.5-0.60.5-0.5-0.5-0.50.4-0.5-1.21.2
Cocaine response after cond. not corrected2.02.44.6-1.71.7-2.11.61.5-1.4-1.5-1.41.4-1.4-1.4-1.41.4-1.4-1.4-1.41.4-1.4-2.02.0
Cocaine response before conditioning1.11.31.7-1.21.2-1.11.11.2-1.2-1.3-1.21.2-1.1-1.1-1.11.1-1.1-1.1-1.31.3-1.1-0.70.7
Saline control response0.81.12.1-1.41.4-0.81.30.9-1.1-0.9-0.91.0-1.0-1.0-1.11.0-1.0-1.0-0.90.9-1.1-0.60.6
Bone: connectivity density0.50.82.11.0-1.01.5-1.0-0.90.80.70.8-0.70.70.70.8-0.70.70.70.8-0.80.71.2-1.2
Bone: cortical apparent density0.30.40.80.7-0.70.9-0.7-0.60.60.40.6-0.50.60.60.5-0.60.60.60.6-0.60.60.8-0.8
Bone: cortical area0.10.10.30.1-0.0-0.3-0.0-0.30.40.50.4-0.40.40.40.2-0.40.40.40.3-0.30.3-0.20.2
Bone: cortical porosity0.30.31.60.6-0.51.3-0.4-0.50.50.50.4-0.30.30.30.3-0.30.30.30.5-0.50.31.0-1.0
Bone: cortical porosity0.20.21.40.5-0.41.2-0.3-0.40.40.40.3-0.20.20.20.2-0.20.20.20.4-0.40.10.9-0.9
Bone: cortical thickness0.20.41.6-0.80.8-1.30.80.5-0.4-0.4-0.40.4-0.4-0.4-0.50.4-0.4-0.4-0.40.4-0.4-1.11.1
Bone: cortical thickness0.00.00.0-0.20.2-0.20.10.1-0.0-0.0-0.00.0-0.0-0.00.00.0-0.0-0.0-0.00.0-0.1-0.10.1
Bone: cortical tissue density0.30.40.90.7-0.80.9-0.8-0.60.60.40.6-0.50.50.60.5-0.60.60.60.6-0.60.60.8-0.8
Condit. Reinf. active minus inactive responses0.10.20.3-0.40.5-0.40.40.3-0.4-0.4-0.30.4-0.4-0.4-0.30.4-0.4-0.4-0.20.2-0.4-0.60.6
Condit. Reinf. active-inactive response ratio0.40.40.8-0.70.8-0.70.70.5-0.6-0.5-0.50.6-0.6-0.6-0.60.6-0.6-0.6-0.40.4-0.6-0.90.9
Condit. Reinf. active responses0.00.00.10.2-0.20.0-0.3-0.20.10.00.1-0.10.10.10.2-0.10.10.10.3-0.30.2-0.20.2
Condit. Reinf. inactive responses0.70.91.51.2-1.20.8-1.2-1.00.90.80.8-0.90.90.91.0-0.90.90.90.9-0.91.10.7-0.7
Incentive salience index mean0.00.00.10.2-0.20.2-0.3-0.20.20.20.2-0.20.20.20.3-0.20.20.20.2-0.20.20.1-0.1
Condit. Reinf. lever presses1.42.02.51.5-1.51.4-1.6-1.31.41.41.4-1.41.41.41.4-1.41.41.41.2-1.21.31.5-1.5
Condit. Reinf. active minus inactive responses2.12.74.4-1.91.8-2.11.81.6-1.6-1.5-1.51.5-1.5-1.5-1.61.5-1.5-1.5-1.61.6-1.5-1.71.7
Condit. Reinf. active-inactive response ratio1.92.24.1-1.61.6-2.01.51.4-1.5-1.5-1.51.3-1.3-1.3-1.41.3-1.3-1.3-1.31.3-1.2-1.71.7
Condit. Reinf. active responses1.62.23.2-1.61.6-1.81.61.4-1.4-1.3-1.41.4-1.4-1.4-1.61.4-1.4-1.4-1.51.5-1.4-1.61.6
Condit. Reinf. inactive responses0.10.10.20.5-0.40.5-0.3-0.40.50.50.4-0.30.30.30.2-0.30.30.30.2-0.30.20.3-0.3
Condit. Reinf. lever presses2.53.54.9-2.12.0-2.22.01.9-1.9-1.8-1.91.8-1.8-1.8-1.81.8-1.8-1.8-1.91.9-1.7-1.81.8
Condit. Reinf. lever reinforcers received2.12.94.1-1.91.9-2.01.91.7-1.6-1.5-1.51.6-1.6-1.6-1.71.6-1.6-1.6-1.71.7-1.6-1.81.8
Conditioned reinforcement - actives1.72.84.02.0-2.01.5-1.8-1.91.91.91.8-1.71.71.71.9-1.71.71.61.3-1.41.51.3-1.3
Conditioned reinforcement - inactives1.62.42.91.5-1.51.1-1.5-1.61.71.71.7-1.71.71.71.6-1.61.61.61.5-1.51.71.1-1.1
Conditioned locomotion0.40.50.80.9-0.90.8-0.7-0.80.80.80.7-0.70.70.70.7-0.70.70.60.4-0.40.50.8-0.8
Patch foraging indifference point 0 sec0.81.52.4-1.31.4-0.51.41.3-1.3-1.2-1.11.3-1.3-1.4-1.31.3-1.3-1.4-1.31.3-1.6-0.40.4
Patch foraging indifference point AUC0.00.00.1-0.10.10.00.20.0-0.2-0.3-0.30.2-0.1-0.1-0.20.2-0.1-0.10.2-0.0-0.10.0-0.0
Delay disc. indifference point, 0s delay0.00.00.20.0-0.0-0.4-0.0-0.00.10.1-0.1-0.00.00.10.0-0.00.00.0-0.10.00.2-0.40.4
Delay disc. indifference point, 16s delay1.01.11.51.1-1.11.2-1.1-1.01.01.10.9-1.11.11.11.0-1.11.11.10.9-1.01.11.2-1.2
Delay disc. indifference point, 2s delay0.40.40.80.8-0.80.8-0.7-0.70.70.60.5-0.60.60.60.6-0.60.60.60.6-0.60.90.6-0.6
Delay disc. indifference point, 24s delay1.11.21.71.2-1.31.3-1.2-1.01.01.00.9-1.01.01.11.1-1.01.11.11.1-1.11.21.1-1.1
Delay disc. indifference point, 4s delay2.02.12.81.6-1.61.4-1.6-1.51.51.31.3-1.41.41.51.4-1.41.41.51.4-1.41.71.2-1.2
Delay disc. indifference point, 8s delay2.22.63.21.8-1.81.8-1.8-1.61.61.51.5-1.51.51.61.6-1.51.51.61.5-1.51.81.5-1.5
Indifference point function ln k0.20.30.60.4-0.40.3-0.6-0.30.40.60.6-0.60.60.50.7-0.60.60.50.1-0.10.50.8-0.8
Indifference point function log k0.20.30.60.4-0.40.3-0.6-0.30.40.60.6-0.60.60.50.7-0.60.60.50.1-0.10.50.8-0.8
Patch foraging total patch changes 0 sec0.91.82.8-1.41.5-0.71.51.4-1.4-1.2-1.11.4-1.4-1.4-1.41.4-1.4-1.4-1.41.4-1.7-0.60.6
Patch foraging total patch changes 12 sec0.91.11.7-1.21.3-0.91.21.1-1.2-1.2-0.91.1-1.1-1.1-1.11.1-1.1-1.1-0.80.9-1.0-0.80.8
Patch foraging total patch changes 18 sec2.03.04.3-1.71.8-1.32.01.6-1.6-1.5-1.71.8-1.8-1.8-1.81.9-1.9-1.9-1.81.7-2.1-1.51.5
Patch foraging total patch changes 24 sec2.33.94.9-2.22.2-2.02.22.0-2.0-1.9-1.91.9-1.9-1.9-1.91.9-1.9-1.9-1.91.9-1.9-1.81.8
Patch foraging total patch changes 6 sec0.10.20.3-0.40.40.50.40.4-0.5-0.4-0.30.4-0.4-0.4-0.50.4-0.4-0.4-0.10.2-0.50.4-0.4
Patch foraging time to switch 0 sec0.20.40.70.8-0.80.6-0.8-0.60.70.60.6-0.60.60.60.6-0.60.60.60.5-0.60.60.3-0.3
Patch foraging water rate 0 sec0.30.51.3-1.11.1-1.01.00.7-0.7-0.6-0.50.6-0.6-0.6-0.70.6-0.6-0.6-0.50.6-0.8-0.70.7
Patch foraging water rate 12 sec0.40.81.8-1.21.2-1.31.11.0-0.9-0.8-0.70.7-0.7-0.7-0.70.7-0.7-0.7-0.70.7-0.8-0.90.9
Patch foraging water rate 18 sec0.30.41.8-1.01.0-1.30.80.6-0.7-0.6-0.50.3-0.3-0.3-0.40.3-0.3-0.3-0.30.3-0.3-0.70.7
Patch foraging water rate 24 sec0.91.32.1-1.31.3-1.51.21.1-1.1-1.1-1.01.0-1.0-1.0-1.11.0-1.0-1.0-1.01.0-1.1-1.31.3
Patch foraging water rate 6 sec0.71.02.4-1.51.6-1.21.31.1-1.2-1.1-0.90.8-0.8-0.8-1.00.8-0.8-0.8-1.00.9-0.8-0.60.6
Seeking ratio, delayed vs. immediate footshock1.82.32.81.5-1.41.2-1.3-1.51.71.71.6-1.61.61.61.4-1.51.61.61.5-1.71.71.2-1.2
Distance traveled before self-admin0.20.20.60.3-0.3-0.3-0.4-0.30.40.40.5-0.50.50.50.6-0.50.50.50.8-0.60.4-0.30.3
Distance traveled after self-admin0.10.10.2-0.20.2-0.5-0.0-0.10.10.20.4-0.40.40.40.4-0.40.40.40.5-0.40.3-0.20.2
Extensor digitorum longus weight0.10.50.70.8-0.80.4-0.8-0.60.80.80.8-0.80.80.80.9-0.80.80.80.6-0.60.70.4-0.4
Bone: elastic displacement0.10.10.4-0.20.3-0.50.30.3-0.1-0.1-0.20.2-0.2-0.2-0.30.2-0.2-0.2-0.20.2-0.3-0.70.7
Bone: elastic work0.60.71.7-0.90.9-1.30.90.9-0.7-0.8-0.80.7-0.7-0.7-0.70.7-0.7-0.7-0.90.8-0.7-1.11.1
Bone: endosteal estimation0.10.10.3-0.30.4-0.00.40.4-0.4-0.3-0.30.4-0.4-0.4-0.20.4-0.4-0.4-0.40.4-0.50.0-0.0
Bone: endosteal perimeter1.22.63.01.7-1.71.7-1.6-1.51.51.71.7-1.61.61.61.6-1.61.61.61.5-1.51.51.7-1.7
Epididymis fat weight0.31.22.6-0.70.7-1.40.91.0-0.8-1.0-1.21.1-1.1-1.1-1.01.1-1.1-1.1-1.00.9-1.0-1.61.6
Delta time in closed arm before/after self-admin0.40.40.60.7-0.70.8-0.7-0.70.60.60.7-0.60.60.60.6-0.60.60.60.7-0.60.50.7-0.7
Delta time in open arm before/after self-admin0.40.40.8-0.80.8-0.50.70.7-0.8-0.7-0.60.6-0.6-0.7-0.40.6-0.6-0.6-0.90.7-0.6-0.30.3
Diff in mean of infusions in LGA sessions0.10.10.90.2-0.3-0.5-0.1-0.10.10.2-0.10.0-0.00.0-0.20.0-0.0-0.0-0.00.0-0.1-0.90.9
Delay discount exponential model param2.22.53.3-1.71.7-1.71.71.6-1.5-1.5-1.41.5-1.5-1.6-1.51.5-1.5-1.6-1.51.5-1.8-1.51.5
Extinction: sum of active levers before priming0.00.00.20.3-0.40.3-0.2-0.10.30.30.1-0.10.10.10.1-0.10.10.10.1-0.2-0.00.1-0.1
Active lever presses in extinction session 60.10.10.4-0.0-0.10.00.20.3-0.1-0.1-0.30.3-0.3-0.3-0.10.3-0.3-0.3-0.10.1-0.6-0.10.1
Bone: final force1.32.03.3-1.61.5-1.81.51.4-1.4-1.3-1.31.3-1.3-1.3-1.41.3-1.3-1.3-1.41.4-1.3-1.61.6
Bone: final moment1.52.54.2-1.71.7-2.11.71.5-1.5-1.4-1.51.4-1.4-1.4-1.51.4-1.4-1.4-1.61.5-1.4-1.81.8
Food consumed during 24 hour testing period1.62.22.9-1.71.7-1.71.61.5-1.5-1.3-1.41.4-1.4-1.4-1.51.4-1.4-1.4-1.61.6-1.4-1.41.4
Glucose0.91.41.7-1.21.2-1.21.21.3-1.3-1.2-1.31.2-1.2-1.2-1.21.2-1.2-1.2-1.21.2-1.1-1.01.0
Heart weight2.13.36.5-1.71.6-2.51.81.7-1.5-1.5-1.71.6-1.6-1.6-1.61.6-1.6-1.6-1.71.7-1.7-2.52.5
Delay discount hyperbolic model param2.52.83.7-1.81.8-1.81.81.7-1.6-1.6-1.51.6-1.6-1.7-1.61.6-1.6-1.7-1.61.6-1.9-1.51.5
Intermittent access intake day 1-15 change0.61.31.71.3-1.31.1-1.2-1.21.21.21.2-1.11.11.11.2-1.11.11.11.0-1.01.01.0-1.0
Intermittent access intake escalation0.91.92.31.5-1.51.4-1.4-1.41.41.41.4-1.41.31.31.5-1.31.31.31.2-1.21.21.4-1.4
Intermittent access intake escalation 20.10.20.20.5-0.50.3-0.4-0.40.40.40.4-0.40.40.40.5-0.40.40.40.3-0.40.30.2-0.2
Intermitt. access day 1 inactive lever presses0.00.10.20.3-0.3-0.1-0.3-0.30.40.40.4-0.40.40.40.2-0.40.40.40.3-0.40.5-0.20.2
Intermitt. access day 15 inactive lever presses0.91.82.41.2-1.21.0-1.3-1.41.41.41.4-1.51.51.51.3-1.51.51.51.3-1.51.51.0-1.0
Intermitt. access escalation Index0.10.10.60.2-0.20.7-0.1-0.20.10.10.1-0.10.10.10.2-0.10.10.10.0-0.10.00.7-0.7
Intermittent access day 1 total infusions0.20.40.60.6-0.60.7-0.5-0.70.60.60.6-0.60.60.60.7-0.60.60.60.4-0.40.50.8-0.8
Intermittent access day 15 total infusions1.62.53.31.6-1.61.8-1.5-1.61.61.61.5-1.51.51.51.7-1.51.51.41.3-1.31.31.8-1.8
Intermittent access terminal intake (last 3 days)1.41.83.11.4-1.41.7-1.3-1.41.31.31.3-1.31.31.21.4-1.21.21.21.1-1.01.11.8-1.8
Intermittent access total infusions1.92.33.21.6-1.61.7-1.4-1.61.61.61.5-1.51.51.41.6-1.41.41.41.3-1.21.21.8-1.8
Intermittent access day 1 locomotion0.10.10.2-0.40.40.10.40.2-0.3-0.3-0.30.3-0.3-0.3-0.20.3-0.3-0.3-0.40.5-0.40.3-0.3
Intermittent access day 15 total locomotion0.40.71.80.9-0.91.3-0.7-0.80.80.80.7-0.70.70.60.8-0.60.60.60.6-0.30.51.3-1.3
Intermittent access total locomotion1.21.42.81.2-1.21.7-1.1-1.21.11.11.1-1.11.01.01.1-1.01.01.00.9-0.80.91.7-1.7
Intermittent access standard deviation0.00.00.1-0.10.1-0.30.20.00.00.0-0.00.0-0.0-0.0-0.00.0-0.0-0.00.00.0-0.2-0.20.2
Left kidney weight0.73.13.9-1.61.6-1.91.71.8-1.8-1.7-2.01.8-1.8-1.8-1.81.8-1.8-1.8-1.91.8-1.6-1.71.7
Right kidney weight0.31.21.7-1.11.0-1.01.11.1-1.2-1.1-1.21.2-1.2-1.1-1.21.2-1.1-1.1-1.31.2-1.0-0.90.9
Cocaine induced anxiety0.00.00.1-0.20.2-0.10.20.1-0.1-0.1-0.10.1-0.1-0.1-0.30.2-0.1-0.1-0.00.0-0.1-0.10.1
Post-drug Anxiety0.00.00.10.2-0.20.3-0.2-0.20.20.20.2-0.20.20.20.1-0.20.20.20.3-0.30.30.2-0.2
Baseline Anxiety0.10.10.10.2-0.20.2-0.3-0.20.20.20.3-0.30.30.20.4-0.30.20.30.1-0.20.30.3-0.3
Tail length5.019.622.5-4.74.7-4.24.74.3-4.5-4.4-4.54.5-4.5-4.5-4.64.5-4.5-4.5-4.24.3-4.4-3.93.9
Length with tail9.541.547.0-6.96.8-6.86.86.5-6.4-6.3-6.56.4-6.4-6.4-6.56.4-6.4-6.4-6.26.3-6.3-6.26.2
Length without tail8.326.633.6-5.55.5-5.85.55.3-5.0-5.0-5.05.0-5.0-5.0-5.15.0-5.0-5.0-5.15.1-4.9-5.25.2
Times rat made contact with spout0.40.40.6-0.60.6-0.60.60.6-0.6-0.6-0.60.7-0.7-0.6-0.80.7-0.6-0.6-0.50.6-0.6-0.80.8
Lifetime Intake2.12.63.81.7-1.71.9-1.5-1.71.61.61.6-1.61.61.51.7-1.51.51.51.4-1.31.32.0-2.0
Liver weight, left0.61.01.3-1.11.1-1.11.10.9-1.0-1.0-1.11.0-1.0-1.0-1.21.0-1.0-1.0-0.90.9-0.8-1.11.1
Liver weight, right1.62.94.5-2.12.1-1.52.01.7-1.9-1.8-1.71.7-1.7-1.7-1.81.7-1.7-1.6-1.71.6-1.5-1.11.1
Locomotor activity6.39.912.1-3.43.4-2.93.33.2-3.2-3.0-3.03.1-3.2-3.2-2.93.2-3.2-3.2-3.33.5-3.5-2.52.5
Locomotor testing distance5.29.412.1-3.33.3-3.03.23.1-3.0-2.8-3.03.0-3.1-3.1-2.63.1-3.1-3.1-3.43.5-3.4-2.52.5
Locomotor testing rearing0.20.30.9-0.60.7-0.40.70.5-0.4-0.2-0.40.5-0.5-0.6-0.20.5-0.6-0.6-0.70.8-0.9-0.40.4
Locomotion in novel chamber0.10.10.30.3-0.3-0.1-0.4-0.40.40.40.5-0.40.40.40.3-0.40.40.40.3-0.40.4-0.20.2
Locomotion in novel chamber post-restriction0.40.60.8-0.70.7-0.70.70.8-0.8-0.8-0.80.9-0.9-0.8-0.80.9-0.9-0.9-0.90.8-0.8-0.80.8
Fecal boli incidents, locomotor time 10.40.61.5-0.70.7-1.20.80.8-0.7-0.6-0.80.7-0.7-0.7-0.60.7-0.7-0.7-0.70.6-0.6-1.21.2
Change in fecal boli incidents, locomotor task0.00.00.0-0.10.1-0.1-0.0-0.00.00.0-0.0-0.00.00.00.0-0.00.00.00.1-0.1-0.1-0.10.1
Time >=10cm from walls, locomotor time 10.20.20.90.1-0.10.7-0.3-0.40.20.30.5-0.40.40.40.3-0.40.40.40.4-0.50.30.9-0.9
Bouts of movement, locomotor time 10.10.10.2-0.40.4-0.30.50.2-0.2-0.2-0.30.2-0.2-0.2-0.30.2-0.2-0.2-0.10.1-0.2-0.10.1
Total resting periods, locomotor time 10.00.00.2-0.30.3-0.30.40.1-0.1-0.1-0.30.1-0.2-0.1-0.30.2-0.2-0.2-0.10.0-0.1-0.10.1
Rest time, locomotor task time 10.40.51.00.7-0.70.1-0.7-0.80.90.90.5-0.80.80.80.7-0.80.80.80.8-1.00.9-0.00.0
Distance moved, locomotor task time 11.21.82.0-1.31.3-1.31.31.3-1.3-1.4-1.11.3-1.3-1.3-1.41.3-1.3-1.3-1.31.4-1.4-1.41.4
Vertical activity count, locomotor time 10.40.81.3-0.90.9-0.70.81.0-1.0-1.0-0.81.0-1.0-1.0-1.00.9-0.9-0.9-0.91.0-1.1-0.80.8
Time >=10cm from walls, locomotor time 21.21.82.6-1.31.3-1.61.41.3-1.2-1.2-1.21.3-1.3-1.3-1.31.3-1.3-1.3-1.31.3-1.2-1.61.6
Bouts of movement, locomotor time 20.00.00.10.1-0.10.00.10.1-0.1-0.0-0.10.1-0.1-0.10.00.1-0.1-0.1-0.20.3-0.0-0.00.0
Total resting periods, locomotor time 20.00.00.10.3-0.30.3-0.1-0.20.20.20.1-0.20.10.10.3-0.10.10.10.10.10.20.3-0.3
Rest time, locomotor task time 20.00.00.10.1-0.10.1-0.1-0.10.10.20.1-0.20.20.20.3-0.20.10.20.1-0.20.30.3-0.3
Distance moved, locomotor task time 21.01.21.9-1.11.1-1.31.11.1-1.0-1.1-1.01.0-1.0-1.0-1.21.0-1.0-1.0-0.90.9-1.0-1.41.4
Vertical activity count, locomotor time 20.00.00.10.0-0.00.10.10.1-0.1-0.2-0.00.2-0.2-0.2-0.30.2-0.1-0.2-0.10.1-0.3-0.10.1
Light reinforcement 10.51.11.6-1.21.2-1.21.01.0-1.3-1.1-1.11.0-1.0-1.0-1.01.0-1.0-1.0-1.11.1-1.0-1.01.0
Light reinforcement 20.10.20.70.1-0.20.4-0.4-0.2-0.10.10.2-0.30.30.30.4-0.40.40.40.3-0.20.50.8-0.8
Bone: marrow area0.10.10.3-0.40.4-0.00.50.4-0.4-0.3-0.30.4-0.4-0.4-0.20.4-0.4-0.4-0.50.5-0.50.0-0.0
Bone: maximum diameter0.30.61.00.7-0.70.5-0.6-0.80.81.00.9-0.90.90.90.7-0.90.90.90.8-0.80.80.5-0.5
Bone: maximum force0.81.52.0-1.41.4-1.41.41.2-1.2-1.1-1.11.1-1.1-1.2-1.21.1-1.2-1.2-1.21.2-1.2-1.21.2
Bone: maximum moment1.01.72.5-1.51.5-1.61.51.3-1.3-1.2-1.21.2-1.2-1.2-1.21.2-1.2-1.2-1.31.3-1.2-1.31.3
Mean time between licks in bursts0.71.62.21.1-1.01.1-1.1-1.11.21.51.4-1.41.41.31.3-1.41.31.31.2-1.21.21.3-1.3
Mean num. licks in bursts0.40.71.0-0.91.0-0.60.80.8-1.0-0.9-0.90.9-0.9-0.8-1.00.9-0.8-0.8-0.80.8-0.7-0.40.4
Cd content in liver0.10.10.30.3-0.30.5-0.3-0.30.30.40.4-0.30.30.30.3-0.30.30.30.3-0.30.30.6-0.6
Co content in liver1.01.11.61.0-0.90.7-1.0-1.11.11.21.3-1.21.21.11.2-1.21.11.11.1-1.11.00.6-0.6
Cu content in liver4.14.85.3-2.22.2-2.22.22.3-2.2-2.1-2.32.2-2.2-2.2-2.22.2-2.2-2.2-2.22.2-2.1-2.12.1
Fe content in liver1.21.42.3-1.11.2-1.21.31.1-1.0-1.0-1.11.2-1.2-1.2-1.21.2-1.2-1.2-1.01.0-1.3-1.51.5
K content in liver0.20.20.3-0.40.3-0.50.30.6-0.5-0.6-0.50.4-0.4-0.4-0.30.4-0.4-0.4-0.60.6-0.3-0.20.2
Mg content in liver0.70.81.40.7-0.80.6-1.0-0.50.60.60.8-1.01.01.01.1-1.01.01.00.6-0.61.01.2-1.2
Mn content in liver0.10.10.3-0.40.3-0.10.10.4-0.4-0.5-0.30.1-0.1-0.1-0.00.1-0.1-0.1-0.40.4-0.10.5-0.5
Na content in liver0.40.40.7-0.50.6-0.30.70.5-0.5-0.5-0.60.7-0.7-0.7-0.80.7-0.8-0.7-0.60.6-0.8-0.70.7
Rb content in liver0.81.02.0-1.31.4-1.01.40.8-0.7-0.7-0.60.9-0.9-0.9-1.10.9-0.9-0.9-0.60.6-1.2-1.21.2
Se content in liver0.00.00.10.1-0.2-0.2-0.20.1-0.2-0.3-0.40.2-0.2-0.1-0.10.1-0.1-0.1-0.10.10.1-0.20.2
Sr content in liver0.10.10.20.0-0.2-0.2-0.40.2-0.3-0.3-0.2-0.10.10.20.3-0.20.20.2-0.30.30.40.5-0.5
Zn content in liver2.22.42.8-1.71.7-1.61.71.7-1.6-1.6-1.61.5-1.5-1.5-1.61.5-1.5-1.6-1.71.7-1.5-1.21.2
Bone: minimum diameter0.40.70.90.7-0.60.6-0.6-0.80.81.00.9-0.90.90.90.9-0.90.90.90.8-0.80.80.9-0.9
Time in familiar zone, hab. session 11.21.11.81.1-1.00.9-0.9-1.21.31.31.2-1.11.11.11.1-1.11.01.01.2-1.20.90.6-0.6
Time in novel zone, hab. session 10.50.50.9-0.80.7-0.70.60.8-0.9-0.9-0.80.8-0.7-0.7-0.80.7-0.7-0.7-0.70.7-0.6-0.60.6
Total zone transitions, hab. session 10.60.81.3-0.90.8-0.70.71.1-1.2-1.1-1.10.9-0.9-0.9-0.80.9-0.9-0.9-1.01.0-0.7-0.20.2
Total locomotion distance, hab. session 10.20.30.6-0.60.5-0.60.40.6-0.8-0.7-0.70.6-0.6-0.6-0.60.6-0.5-0.5-0.60.6-0.4-0.40.4
Locomotion velocity, hab. session 10.20.30.6-0.60.5-0.50.40.7-0.8-0.8-0.80.6-0.6-0.6-0.60.6-0.6-0.6-0.60.6-0.4-0.30.3
Time in familiar zone, hab. session 20.40.40.80.5-0.40.2-0.3-0.60.80.90.8-0.80.70.70.6-0.70.70.70.6-0.60.50.2-0.2
Time in novel zone, hab. session 20.00.00.1-0.10.10.30.00.1-0.2-0.2-0.10.2-0.2-0.2-0.10.2-0.2-0.2-0.10.1-0.20.2-0.2
Total zone transitions, hab. session 20.10.10.3-0.20.1-0.20.10.5-0.5-0.4-0.50.3-0.3-0.2-0.10.2-0.2-0.2-0.50.5-0.10.1-0.1
Total locomotion distance, hab. session 20.20.30.6-0.40.4-0.50.40.7-0.7-0.7-0.80.6-0.6-0.5-0.60.6-0.5-0.5-0.60.6-0.4-0.40.4
Locomotion velocity, hab. session 20.10.20.5-0.20.2-0.30.20.6-0.6-0.6-0.70.5-0.5-0.4-0.50.5-0.4-0.4-0.50.5-0.2-0.20.2
Novel to familiar place preference ratio0.70.81.0-1.01.0-0.11.00.9-1.0-0.9-0.91.0-1.0-1.0-0.81.0-1.0-1.0-1.01.0-1.00.2-0.2
Novelty place preference0.70.81.0-1.01.00.01.00.9-1.0-0.9-0.90.9-0.9-1.0-0.81.0-1.0-1.0-1.01.0-0.90.3-0.3
Time in novel zone, NPP test0.91.01.4-1.11.2-0.21.21.1-1.1-1.0-1.01.1-1.1-1.1-0.91.1-1.1-1.1-1.11.1-1.10.1-0.1
Total zone transitions, NPP test2.23.24.7-1.81.7-1.71.62.1-2.0-2.0-2.11.8-1.8-1.8-1.71.8-1.7-1.8-2.22.2-1.6-1.01.0
Total locomotion distance, NPP test0.91.31.9-1.00.9-1.10.91.3-1.2-1.3-1.41.2-1.2-1.1-1.21.1-1.1-1.1-1.21.2-0.9-0.90.9
Locomotion velocity, NPP test1.01.42.0-1.11.0-1.11.01.3-1.3-1.4-1.41.2-1.2-1.2-1.21.2-1.2-1.2-1.31.3-1.0-0.80.8
Intraocular pressure0.91.42.3-1.01.0-1.01.21.0-1.0-1.0-1.01.2-1.2-1.2-1.11.2-1.2-1.2-1.01.1-1.4-1.51.5
Delta distance traveled before/after self-admin0.10.10.3-0.50.6-0.20.40.3-0.3-0.3-0.20.2-0.2-0.2-0.30.1-0.2-0.2-0.30.2-0.20.0-0.0
Delta ambulatory time before/after self-admin1.01.32.3-1.51.5-0.91.41.1-1.2-1.2-1.11.1-1.1-1.1-1.11.0-1.1-1.1-1.11.1-1.2-0.50.5
Parametrial fat weight0.81.82.6-1.51.5-1.41.31.4-1.6-1.5-1.41.4-1.3-1.3-1.41.3-1.2-1.3-1.31.3-1.2-1.11.1
Pavlov. Cond. lever latency4.15.26.0-2.42.4-2.02.42.3-2.2-2.3-2.22.4-2.4-2.4-2.42.4-2.4-2.4-2.22.2-2.3-2.02.0
Pavlov. Cond. magazine entry latency7.49.510.43.2-3.22.9-3.2-3.13.13.23.2-3.23.23.13.1-3.23.13.13.0-3.03.02.8-2.8
Pavlov. Cond. change in total contacts1.51.52.11.2-1.11.1-1.1-1.31.31.41.4-1.31.31.31.2-1.31.31.31.3-1.31.11.0-1.0
Pavlov. Cond. index score6.17.78.62.9-2.92.5-2.9-2.82.82.92.9-2.92.92.92.8-2.92.92.92.7-2.72.72.4-2.4
Pavlov. Cond. latency score6.07.58.22.9-2.92.5-2.8-2.72.72.82.8-2.82.82.82.8-2.82.82.82.7-2.72.72.5-2.5
Pavlov. Cond. lever contacts2.53.03.61.8-1.91.5-1.9-1.71.71.81.7-1.81.81.81.7-1.81.81.81.6-1.61.81.5-1.5
Pavlov. Cond. magazine entry number7.59.510.5-3.23.2-2.93.13.1-3.2-3.2-3.23.2-3.2-3.1-3.13.2-3.1-3.1-3.03.0-2.9-2.72.7
Pavlov. Cond. intertrial magazine entries0.50.60.7-0.70.7-0.80.80.7-0.7-0.7-0.80.8-0.8-0.8-0.70.8-0.8-0.8-0.70.7-0.8-0.80.8
Pavlov. Cond. lever-magazine prob. diff.5.46.77.62.8-2.72.2-2.7-2.62.72.82.7-2.72.72.72.6-2.72.72.72.5-2.52.52.1-2.1
Pavlov. Cond. response bias6.68.29.33.0-3.12.5-3.0-2.82.93.02.9-3.03.03.02.9-3.03.02.92.7-2.72.82.4-2.4
Pavlov. Cond. lever latency0.91.21.71.3-1.21.3-1.1-1.21.21.11.1-1.01.01.00.9-1.01.01.01.3-1.21.00.9-0.9
Pavlov. Cond. magazine entry latency0.10.10.30.2-0.3-0.1-0.4-0.00.10.20.2-0.30.30.30.5-0.30.30.30.1-0.10.30.3-0.3
Pavlov. Cond. change in total contacts2.94.67.0-2.52.5-2.72.42.3-2.2-2.0-2.12.0-2.0-2.0-1.92.0-2.0-2.0-2.12.1-2.0-2.12.1
Pavlov. Cond. index score0.30.51.2-0.80.7-1.10.60.8-0.8-0.7-0.70.6-0.6-0.6-0.40.6-0.6-0.6-0.80.8-0.5-0.60.6
Pavlov. Cond. latency score0.20.30.8-0.60.6-0.90.50.7-0.6-0.5-0.50.4-0.4-0.4-0.30.4-0.4-0.4-0.70.6-0.4-0.40.4
Pavlov. Cond. lever contacts1.11.62.0-1.41.4-1.41.31.4-1.4-1.3-1.31.2-1.2-1.2-1.11.2-1.2-1.2-1.41.3-1.1-0.90.9
Pavlov. Cond. magazine entry number0.10.10.3-0.30.3-0.10.30.1-0.2-0.4-0.30.4-0.4-0.4-0.50.4-0.4-0.4-0.10.2-0.3-0.40.4
Pavlov. Cond. intertrial magazine entries0.61.01.81.0-0.91.3-0.8-1.11.11.11.1-0.90.90.90.8-0.90.90.91.0-1.00.71.0-1.0
Pavlov. Cond. lever-magazine prob. diff.0.30.41.0-0.70.7-1.00.50.8-0.7-0.6-0.60.5-0.5-0.5-0.30.5-0.5-0.5-0.70.7-0.4-0.50.5
Pavlov. Cond. response bias0.20.30.6-0.60.6-0.80.50.6-0.6-0.5-0.50.4-0.4-0.4-0.30.4-0.4-0.4-0.60.6-0.4-0.40.4
Time in closed arm before self-admin0.91.21.8-1.11.1-1.31.01.1-0.9-1.0-1.01.1-1.1-1.0-0.91.1-1.1-1.1-1.41.1-1.0-1.21.2
Time in closed arm after self-admin0.10.20.20.4-0.40.0-0.5-0.40.50.30.5-0.40.40.50.4-0.40.40.40.4-0.40.4-0.10.1
Time in open arm before self-admin1.31.42.01.4-1.41.4-1.1-1.31.21.30.9-1.11.11.10.7-1.11.11.11.4-1.30.91.1-1.1
Time in open arm after self-admin0.50.52.30.6-0.61.4-0.5-0.60.40.50.4-0.40.40.40.5-0.40.40.40.3-0.60.41.5-1.5
Bone: periosteal estimation0.00.00.2-0.30.4-0.30.40.2-0.10.0-0.10.1-0.1-0.2-0.10.1-0.2-0.2-0.20.2-0.3-0.10.1
Bone: periosteal perimeter1.01.72.11.3-1.21.3-1.2-1.31.31.51.4-1.31.31.31.3-1.31.31.31.2-1.21.21.2-1.2
Bone: post-yield work0.00.00.00.0-0.00.2-0.00.1-0.1-0.1-0.10.1-0.1-0.10.00.1-0.1-0.1-0.20.2-0.10.2-0.2
Progressive ratio test 1 active lever presses0.10.10.70.1-0.10.7-0.0-0.20.10.10.1-0.00.00.00.2-0.0-0.0-0.0-0.10.2-0.10.9-0.9
Progressive ratio test 1 breakpoint0.10.10.70.2-0.20.8-0.1-0.20.10.10.1-0.10.10.00.2-0.00.00.0-0.10.1-0.10.9-0.9
Progressive ratio test 1 inactive lever presses0.30.40.60.6-0.60.4-0.6-0.70.70.70.7-0.70.70.70.7-0.70.70.70.6-0.60.70.4-0.4
Progressive ratio test 2 active lever presses2.32.73.31.8-1.81.7-1.6-1.81.81.81.7-1.71.61.71.6-1.61.61.61.5-1.41.41.6-1.6
Progressive ratio test 2 breakpoint2.42.73.31.8-1.81.7-1.6-1.81.81.81.7-1.71.71.71.6-1.61.71.61.5-1.51.51.6-1.6
Progressive ratio test 2 inactive lever presses2.13.44.22.0-2.01.4-1.8-2.02.12.12.0-2.02.02.01.9-1.91.91.91.6-1.81.81.3-1.3
Incentive Sensitization - Responses2.02.83.41.8-1.81.2-1.6-1.81.81.81.8-1.81.81.81.6-1.81.81.81.6-1.71.61.1-1.1
Incentive Sensitization - Breakpoint2.22.83.41.8-1.81.2-1.6-1.81.81.81.8-1.81.81.81.6-1.81.81.81.6-1.71.61.1-1.1
Sum of active levers in priming session hrs 5-60.10.10.30.5-0.60.6-0.3-0.10.30.2-0.1-0.00.00.1-0.0-0.00.00.00.2-0.3-0.00.3-0.3
Progressive ratio2.53.95.1-2.22.3-2.12.12.0-2.0-1.9-1.81.9-1.9-1.9-2.01.9-1.9-1.9-2.11.9-1.8-1.91.9
Food seeking constrained by brief footshock1.11.31.91.1-1.11.0-1.1-1.21.21.21.4-1.21.21.20.9-1.21.21.21.1-1.21.21.0-1.0
Seeking ratio, punishment vs. effort4.46.47.12.6-2.72.4-2.6-2.62.52.52.6-2.52.62.62.4-2.62.62.62.7-2.52.42.3-2.3
Retroperitoneal fat weight1.66.97.7-2.72.7-2.72.62.6-2.8-2.7-2.82.7-2.7-2.6-2.72.6-2.6-2.6-2.42.6-2.5-2.52.5
Reaction time number correct0.20.40.60.5-0.40.7-0.4-0.60.60.80.8-0.70.70.70.5-0.70.70.70.7-0.70.40.7-0.7
Reaction time mean minus median0.00.10.2-0.30.2-0.10.10.2-0.3-0.4-0.20.3-0.3-0.3-0.30.3-0.3-0.3-0.50.5-0.20.2-0.2
Reaction time mean minus median AUC0.10.30.7-0.80.8-0.40.50.5-0.7-0.7-0.50.6-0.6-0.6-0.50.6-0.6-0.6-0.80.7-0.5-0.10.1
Reaction time num false alarms0.30.40.70.6-0.50.8-0.5-0.60.60.80.7-0.50.50.50.7-0.50.50.50.5-0.50.30.8-0.8
Reaction time num false alarms AUC0.10.20.60.3-0.30.8-0.3-0.40.30.40.4-0.30.30.20.4-0.30.20.20.3-0.30.10.8-0.8
Reaction time trials correct on left0.20.40.60.5-0.40.7-0.4-0.60.60.80.8-0.70.70.70.5-0.70.70.70.7-0.70.40.7-0.7
Reaction time trials on left0.20.50.60.5-0.50.7-0.4-0.70.70.80.8-0.70.70.70.5-0.70.70.70.7-0.70.50.7-0.7
Reaction time mean0.00.00.20.2-0.20.5-0.1-0.00.00.0-0.10.1-0.1-0.10.00.1-0.2-0.2-0.20.3-0.30.4-0.4
Reaction time mean AUC0.00.10.30.2-0.20.6-0.2-0.10.10.10.10.0-0.0-0.10.10.0-0.1-0.1-0.20.2-0.20.5-0.5
Median of all reaction times0.10.10.40.4-0.40.7-0.2-0.20.30.20.1-0.00.00.00.2-0.0-0.0-0.00.00.0-0.10.5-0.5
Reaction time omissions0.20.31.10.8-0.71.0-0.5-0.70.70.60.6-0.40.40.30.3-0.40.30.30.4-0.40.20.5-0.5
Reaction time false alarm rate0.00.00.20.2-0.20.5-0.2-0.20.20.20.2-0.10.10.10.2-0.10.10.10.1-0.10.00.4-0.4
Reaction time premature initiation rate2.23.03.3-1.81.8-1.81.71.7-1.8-1.8-1.71.8-1.7-1.8-1.71.7-1.7-1.7-1.71.8-1.7-1.71.7
Reaction time premature initiations0.91.62.0-1.41.4-1.31.31.3-1.3-1.3-1.11.2-1.2-1.3-1.31.2-1.2-1.2-1.11.2-1.3-1.21.2
Std. dev. reaction times0.10.20.5-0.20.20.30.20.2-0.3-0.3-0.30.4-0.4-0.4-0.30.4-0.4-0.5-0.70.7-0.50.4-0.4
Reaction time trials completed0.20.50.60.5-0.50.7-0.4-0.70.70.80.8-0.70.70.70.5-0.70.70.70.7-0.70.50.7-0.7
Reaction time trials AUC0.30.60.90.7-0.60.8-0.5-0.80.80.90.9-0.80.80.80.6-0.80.80.80.8-0.80.50.8-0.8
Run reversals in cocaine runway, females1.21.21.71.2-1.11.0-1.3-1.20.91.01.1-1.11.11.11.0-1.11.11.11.3-1.11.20.9-0.9
Run reversals in cocaine runway, males1.21.22.0-1.31.3-1.41.21.1-1.1-1.1-1.00.9-0.9-1.0-1.10.9-0.9-0.9-0.91.0-1.0-1.31.3
Latency to leave start box in cocaine runway0.40.41.2-0.80.8-1.10.70.7-0.6-0.6-0.50.5-0.5-0.5-0.70.5-0.5-0.5-0.30.5-0.4-1.01.0
Latency to leave start box in cocaine runway, F1.01.11.7-1.31.3-1.31.21.2-1.1-1.0-0.91.0-0.9-1.0-1.00.9-0.9-1.0-0.80.9-0.9-1.21.2
Latency to leave start box in cocaine runway, M0.90.81.21.1-1.10.4-1.0-1.01.11.10.9-0.90.91.00.7-1.01.01.01.0-0.91.00.2-0.2
Std. dev. time between licks in bursts3.24.35.62.0-1.91.6-1.9-2.02.12.42.3-2.32.22.22.4-2.22.22.22.0-2.02.01.8-1.8
Total sessions with >9 infusions0.50.60.80.8-0.80.3-0.7-0.80.90.90.8-0.80.80.80.8-0.90.80.80.8-0.60.60.2-0.2
Short access day 1 total inactive lever presses3.04.05.02.1-2.11.7-2.0-2.12.22.22.1-2.12.12.02.2-2.12.02.01.8-1.81.81.6-1.6
Short access day 10 total inactive lever presses0.10.41.7-0.70.7-1.30.60.4-0.3-0.3-0.30.3-0.3-0.3-0.50.3-0.3-0.3-0.40.2-0.1-1.21.2
Short access day 1 total infusions2.83.64.01.9-1.91.7-1.9-2.02.02.02.0-2.02.02.02.0-2.02.02.01.9-1.81.81.7-1.7
Short access day 10 total infusions2.32.93.81.7-1.71.9-1.6-1.81.71.71.7-1.71.71.71.7-1.71.61.61.5-1.41.52.0-2.0
Short access total infusions3.34.25.22.2-2.22.3-2.0-2.12.12.12.0-2.02.02.02.1-2.02.02.01.9-1.71.82.3-2.3
Short access day 1 locomotion0.50.60.80.9-0.90.2-0.8-0.80.90.90.8-0.90.90.90.8-0.90.90.90.7-0.70.80.0-0.0
Short access day 10 total locomotion0.00.00.1-0.20.20.20.20.1-0.1-0.1-0.10.2-0.2-0.2-0.20.2-0.2-0.2-0.10.3-0.30.4-0.4
Short access total locomotion0.10.10.10.4-0.40.4-0.3-0.30.30.30.3-0.30.30.30.3-0.30.30.20.2-0.00.10.3-0.3
One hour access (0.3 mA shock)0.70.82.20.8-0.81.3-0.7-1.00.90.90.9-0.80.80.80.8-0.70.70.70.5-0.60.61.5-1.5
Compulsive drug intake0.60.81.00.7-0.71.0-0.9-0.80.70.70.8-0.90.90.90.8-0.90.90.90.9-1.01.01.0-1.0
One hour access (shock baseline)0.40.60.80.8-0.90.9-0.6-0.90.90.90.8-0.70.70.70.8-0.70.70.60.4-0.50.50.9-0.9
Social response proportion0.20.20.5-0.50.5-0.20.50.4-0.5-0.5-0.30.5-0.5-0.5-0.70.5-0.5-0.5-0.30.3-0.4-0.50.5
Social responses0.30.40.7-0.70.8-0.20.70.6-0.8-0.6-0.60.6-0.6-0.6-0.70.6-0.6-0.6-0.60.5-0.6-0.10.1
Social time0.40.61.20.8-0.80.6-0.9-0.70.70.70.6-0.80.80.80.7-0.80.80.81.1-0.90.90.6-0.6
Soleus weight4.513.315.7-3.93.9-4.03.73.8-3.7-3.7-3.73.6-3.6-3.6-3.43.6-3.6-3.6-3.83.8-3.5-3.43.4
Bone: stiffness0.20.30.6-0.70.7-0.60.70.5-0.5-0.5-0.50.5-0.5-0.5-0.60.5-0.5-0.5-0.60.5-0.5-0.50.5
Tibialis anterior weight0.00.10.2-0.10.1-0.50.10.3-0.2-0.1-0.20.2-0.2-0.2-0.10.2-0.2-0.2-0.30.3-0.2-0.50.5
Time to tail flick, vehicle, before self-admin2.02.02.9-1.51.5-1.71.51.4-1.3-1.4-1.41.4-1.4-1.4-1.41.4-1.4-1.4-1.31.3-1.3-1.61.6
Time to tail flick, vehicle, after self-admin0.20.20.5-0.50.5-0.60.40.6-0.5-0.7-0.40.4-0.4-0.4-0.30.4-0.4-0.4-0.10.3-0.3-0.60.6
Time to tail flick, test, before self-admin0.10.20.80.3-0.30.9-0.3-0.20.10.00.0-0.10.10.20.1-0.20.20.20.4-0.40.30.8-0.8
Time to tail flick, test, after self-admin0.20.20.40.7-0.60.4-0.4-0.50.70.50.3-0.40.40.50.4-0.40.50.40.6-0.60.40.2-0.2
Delta time to tail flick, vehicle, before/after SA0.40.40.60.6-0.50.6-0.6-0.60.50.50.8-0.70.70.70.7-0.70.70.70.7-0.50.80.7-0.7
Delta time to tail flick, test, before/after SA0.10.10.30.4-0.40.1-0.3-0.40.50.50.4-0.40.40.40.4-0.30.30.30.4-0.30.20.1-0.1
Tibia length7.119.622.9-4.84.7-4.84.54.6-4.5-4.5-4.64.3-4.3-4.3-4.34.3-4.3-4.3-4.74.7-4.2-3.83.8
Ambulatory time before self-admin0.50.71.40.9-0.90.2-1.0-0.70.80.90.9-0.90.90.91.1-0.90.90.91.2-1.00.90.1-0.1
Ambulatory time after self-admin0.00.00.1-0.30.4-0.40.10.2-0.1-0.10.1-0.10.10.10.3-0.10.10.10.3-0.20.0-0.10.1
Bone: tissue strength4.04.06.1-2.22.2-2.52.12.0-1.9-1.9-1.91.9-1.9-1.9-1.81.9-1.9-1.9-1.91.9-1.9-2.22.2
Total heroin consumption2.12.43.2-1.51.4-1.61.71.6-1.5-1.4-1.71.5-1.5-1.6-1.51.5-1.6-1.6-1.31.3-1.8-1.71.7
Bone: trabecular number0.81.32.61.2-1.21.6-1.2-1.11.01.01.0-1.01.01.01.1-1.01.01.00.9-1.00.91.5-1.5
Bone: trabecular spacing1.92.54.6-1.81.8-2.11.71.5-1.5-1.5-1.51.4-1.4-1.4-1.61.4-1.4-1.4-1.31.4-1.3-2.02.0
Bone: trabecular thickness0.00.00.2-0.0-0.00.3-0.10.2-0.3-0.3-0.30.2-0.2-0.2-0.10.2-0.1-0.1-0.20.2-0.10.4-0.4
Bone: trabecular tissue density0.40.50.8-0.80.8-0.70.80.8-0.8-0.9-0.80.7-0.7-0.7-0.80.7-0.7-0.7-0.70.8-0.6-0.50.5
Water consumed over 24 hours0.10.10.5-0.30.3-0.70.30.2-0.2-0.2-0.20.1-0.1-0.1-0.30.1-0.1-0.1-0.20.2-0.1-0.70.7
Number of responses in last shaping day0.20.20.30.4-0.40.0-0.4-0.50.50.50.5-0.50.50.50.6-0.50.50.50.5-0.50.50.0-0.0