Hub : Traits

Intermitt. access day 15 inactive lever presses

Intermittent access day 15 total inactive lever presses

Tags: Behavior · Intermittent access · Cocaine

Project: p50_paul_meyer_2020

6 loci · 7 genes with independent associations · 8 total associated genes

Significant Loci

#	Chr	Start pos	End pos	# assoc genes	# joint models	Best TWAS P	Best GWAS P	Cond GWAS P	Joint genes
1	chr6	29955132	31592606	2	2	2.00e-08	9.83e-04	1.00e+00	Supt7l Zfp513
2	chr7	92127461	93066096	1	1	5.14e-59	4.13e-01	1.00e+00	Ndufb9
3	chr7	126707686	128105211	1	1	8.56e-09	1.96e-04	9.19e-01	Adamts20
4	chr8	41432021	42517271	1	1	5.60e-19	2.88e-01	6.77e-09	Foxred1
5	chr9	83390749	84777604	2	1	0.00e+00	1.08e-01	1.00e+00	Retreg2
6	chr13	84702566	86100919	1	1	2.50e-08	2.17e-01	6.92e-32	Olfml2b

Pleiotropic Associations

Trait	Chi2 ratio	# genes+	# genes++	% genes++	Corr	Corr P	Genes
BMI with tail	964.63	4	2	28.6	-1	9.43e-04	Foxred1 Ndufb9 Olfml2b Retreg2
BMI without tail	36010.59	3	2	28.6	1	9.59e-05	Ndufb9 Olfml2b Retreg2
Body weight	5.27	5	1	14.3	-0.09	8.88e-01	Ndufb9 Olfml2b Retreg2 Supt7l Zfp513
Epididymis fat weight	21696.56	4	3	42.9	1	5.16e-06	Ndufb9 Retreg2 Supt7l Zfp513
Glucose	1186.24	2	1	14.3	0	1.00e+00	Ndufb9 Retreg2
Heart weight	6758.27	2	1	14.3	0	1.00e+00	Ndufb9 Retreg2
Left kidney weight	28256.22	4	2	28.6	-1	8.35e-06	Foxred1 Ndufb9 Olfml2b Retreg2
Right kidney weight	29216.58	3	2	28.6	-1	4.55e-04	Foxred1 Ndufb9 Retreg2
Tail length	46068.54	1	1	14.3	0	1.00e+00	Retreg2
Length with tail	1231.47	4	2	28.6	1	3.50e-05	Foxred1 Ndufb9 Retreg2 Supt7l
Length without tail	43109.4	2	1	14.3	0	1.00e+00	Ndufb9 Retreg2
Liver weight, left	7260.57	2	1	14.3	0	1.00e+00	Ndufb9 Retreg2
Liver weight, right	128.97	2	1	14.3	0	1.00e+00	Ndufb9 Retreg2
Parametrial fat weight	207.55	3	1	14.3	0	1.00e+00	Foxred1 Retreg2 Supt7l
Retroperitoneal fat weight	4020.02	3	2	28.6	1	7.33e-04	Retreg2 Supt7l Zfp513
Intraocular pressure	10023.51	3	1	14.3	-1	1.40e-06	Retreg2 Supt7l Zfp513
Extensor digitorum longus weight	2342.58	2	1	14.3	0	1.00e+00	Retreg2 Supt7l
Soleus weight	26.34	5	1	14.3	0.94	1.86e-02	Adamts20 Ndufb9 Olfml2b Retreg2 Supt7l
Tibialis anterior weight	1629.16	3	1	14.3	0	1.00e+00	Olfml2b Retreg2 Supt7l
Tibia length	1088.79	3	1	14.3	0	1.00e+00	Adamts20 Ndufb9 Retreg2
Number of licking bursts	78566.65	1	1	14.3	0	1.00e+00	Retreg2
Food consumed during 24 hour testing period	53102.69	1	1	14.3	0	1.00e+00	Retreg2
Times rat made contact with spout	158.46	2	1	14.3	0	1.00e+00	Ndufb9 Retreg2
Mean time between licks in bursts	66505.63	2	1	14.3	0	1.00e+00	Ndufb9 Retreg2
Mean num. licks in bursts	71307.17	1	1	14.3	0	1.00e+00	Retreg2
Std. dev. time between licks in bursts	47023.26	1	1	14.3	0	1.00e+00	Retreg2
Water consumed over 24 hours	51709.36	1	1	14.3	0	1.00e+00	Retreg2
Patch foraging indifference point 0 sec	115003.89	1	1	14.3	0	1.00e+00	Retreg2
Patch foraging indifference point AUC	33285.61	3	1	14.3	-1	9.60e-05	Ndufb9 Retreg2 Zfp513
Indifference point function ln k	35513.76	3	2	28.6	1	1.89e-06	Ndufb9 Olfml2b Retreg2
Indifference point function log k	35513.76	3	2	28.6	1	1.89e-06	Ndufb9 Olfml2b Retreg2
Patch foraging total patch changes 0 sec	60133.55	1	1	14.3	0	1.00e+00	Retreg2
Patch foraging total patch changes 12 sec	3633.22	3	2	28.6	0	1.00e+00	Foxred1 Ndufb9 Retreg2
Patch foraging total patch changes 18 sec	39260.42	2	1	14.3	0	1.00e+00	Ndufb9 Retreg2
Patch foraging total patch changes 24 sec	55715.71	2	2	28.6	0	1.00e+00	Ndufb9 Retreg2
Patch foraging total patch changes 6 sec	16328.34	2	2	28.6	0	1.00e+00	Ndufb9 Retreg2
Patch foraging time to switch 0 sec	39162.38	3	2	28.6	1	4.12e-04	Ndufb9 Olfml2b Retreg2
Patch foraging water rate 0 sec	37207.21	3	1	14.3	-1	3.55e-04	Ndufb9 Olfml2b Retreg2
Patch foraging water rate 12 sec	80937.39	1	1	14.3	0	1.00e+00	Retreg2
Patch foraging water rate 18 sec	34430.05	2	1	14.3	0	1.00e+00	Ndufb9 Retreg2
Patch foraging water rate 24 sec	2349.61	2	1	14.3	0	1.00e+00	Retreg2 Supt7l
Patch foraging water rate 6 sec	1993.4	2	2	28.6	0	1.00e+00	Ndufb9 Retreg2
Locomotor activity	10.62	2	0	0	0	1.00e+00	Foxred1 Retreg2
Locomotor testing distance	22371.38	3	1	14.3	-1	6.26e-04	Foxred1 Ndufb9 Retreg2
Locomotor testing rearing	38111.84	3	1	14.3	-1	3.49e-04	Foxred1 Ndufb9 Retreg2
Light reinforcement 1	38816.57	3	1	14.3	-1	4.30e-05	Retreg2 Supt7l Zfp513
Light reinforcement 2	26980.57	3	1	14.3	-1	7.20e-05	Retreg2 Supt7l Zfp513
Reaction time number correct	38373.4	3	2	28.6	-1	4.07e-04	Ndufb9 Olfml2b Retreg2
Reaction time mean minus median	51458.33	3	1	14.3	1	2.51e-04	Ndufb9 Olfml2b Retreg2
Reaction time mean minus median AUC	52106.05	3	2	28.6	1	2.87e-04	Ndufb9 Olfml2b Retreg2
Reaction time num false alarms	57075.22	1	1	14.3	0	1.00e+00	Retreg2
Reaction time num false alarms AUC	53252.06	1	1	14.3	0	1.00e+00	Retreg2
Reaction time trials correct on left	38373.4	3	2	28.6	-1	4.07e-04	Ndufb9 Olfml2b Retreg2
Reaction time trials on left	37504.84	3	2	28.6	-1	4.09e-04	Ndufb9 Olfml2b Retreg2
Reaction time mean	47198.46	1	1	14.3	0	1.00e+00	Retreg2
Reaction time mean AUC	56678.81	1	1	14.3	0	1.00e+00	Retreg2
Median of all reaction times	15714.05	1	1	14.3	0	1.00e+00	Retreg2
Reaction time omissions	11426.44	2	1	14.3	0	1.00e+00	Ndufb9 Retreg2
Reaction time false alarm rate	448.49	2	1	14.3	0	1.00e+00	Ndufb9 Retreg2
Reaction time premature initiation rate	36877.02	1	1	14.3	0	1.00e+00	Retreg2
Reaction time premature initiations	69365.42	1	1	14.3	0	1.00e+00	Retreg2
Std. dev. reaction times	37377.78	3	1	14.3	1	2.97e-04	Ndufb9 Olfml2b Retreg2
Reaction time trials completed	37504.84	3	2	28.6	-1	4.09e-04	Ndufb9 Olfml2b Retreg2
Reaction time trials AUC	37930.42	3	1	14.3	-1	3.84e-04	Ndufb9 Olfml2b Retreg2
Social response proportion	35302.65	1	1	14.3	0	1.00e+00	Retreg2
Social responses	2844.13	2	1	14.3	0	1.00e+00	Ndufb9 Retreg2
Social time	44238.34	1	1	14.3	0	1.00e+00	Retreg2
Conditioned locomotion	6074.35	1	1	14.3	0	1.00e+00	Retreg2
Cocaine response after cond. corrected	32916.02	1	1	14.3	0	1.00e+00	Retreg2
Cocaine response after cond. not corrected	32133.24	1	1	14.3	0	1.00e+00	Retreg2
Cocaine response before conditioning	2800.41	1	1	14.3	0	1.00e+00	Retreg2
Saline control response	6484.47	1	1	14.3	0	1.00e+00	Retreg2
Condit. Reinf. active minus inactive responses	53410.48	1	1	14.3	0	1.00e+00	Retreg2
Condit. Reinf. active-inactive response ratio	45793.79	2	1	14.3	0	1.00e+00	Ndufb9 Retreg2
Condit. Reinf. active responses	9691.24	1	1	14.3	0	1.00e+00	Retreg2
Condit. Reinf. inactive responses	42106.18	1	1	14.3	0	1.00e+00	Retreg2
Condit. Reinf. lever presses	7939.8	2	1	14.3	0	1.00e+00	Ndufb9 Retreg2
Condit. Reinf. lever reinforcers received	2000.77	1	1	14.3	0	1.00e+00	Retreg2
Pavlov. Cond. lever latency	10912.53	1	1	14.3	0	1.00e+00	Retreg2
Pavlov. Cond. magazine entry latency	49418.79	1	1	14.3	0	1.00e+00	Retreg2
Pavlov. Cond. change in total contacts	38264.3	2	1	14.3	0	1.00e+00	Ndufb9 Retreg2
Pavlov. Cond. index score	47988.08	1	1	14.3	0	1.00e+00	Retreg2
Pavlov. Cond. latency score	58476.16	1	1	14.3	0	1.00e+00	Retreg2
Pavlov. Cond. lever contacts	22069.78	1	1	14.3	0	1.00e+00	Retreg2
Pavlov. Cond. magazine entry number	16773.11	1	1	14.3	0	1.00e+00	Retreg2
Pavlov. Cond. intertrial magazine entries	52471.02	1	1	14.3	0	1.00e+00	Retreg2
Pavlov. Cond. lever-magazine prob. diff.	44871.67	1	1	14.3	0	1.00e+00	Retreg2
Pavlov. Cond. response bias	5169.79	1	1	14.3	0	1.00e+00	Retreg2
Conditioned reinforcement - actives	47882.45	3	2	28.6	1	1.93e-05	Ndufb9 Olfml2b Retreg2
Conditioned reinforcement - inactives	22155.81	6	2	28.6	1	2.91e-13	Foxred1 Ndufb9 Olfml2b Retreg2 Supt7l Zfp513
Conditioned locomotion	10356.87	4	2	28.6	1	5.32e-04	Foxred1 Ndufb9 Olfml2b Retreg2
Intermittent access intake day 1-15 change	52658.74	3	2	28.6	1	1.90e-06	Foxred1 Olfml2b Retreg2
Intermittent access intake escalation	52397.39	3	2	28.6	1	1.66e-05	Foxred1 Olfml2b Retreg2
Intermittent access intake escalation 2	36026.22	3	2	28.6	0	1.00e+00	Foxred1 Olfml2b Retreg2
Intermitt. access day 1 inactive lever presses	59140.84	3	1	14.3	1	1.02e-04	Ndufb9 Olfml2b Retreg2
Intermitt. access escalation Index	46254.64	3	1	14.3	-1	2.01e-04	Ndufb9 Olfml2b Retreg2
Intermittent access day 1 total infusions	31110.8	4	1	14.3	-1	4.33e-07	Foxred1 Olfml2b Retreg2 Supt7l
Intermittent access day 15 total infusions	32884.79	3	3	42.9	1	3.75e-05	Foxred1 Olfml2b Retreg2
Intermittent access terminal intake (last 3 days)	27752.75	3	3	42.9	0	1.00e+00	Foxred1 Olfml2b Retreg2
Intermittent access total infusions	235.55	3	1	14.3	0	1.00e+00	Foxred1 Olfml2b Retreg2
Intermittent access day 1 locomotion	26123.05	3	2	28.6	-1	1.29e-04	Foxred1 Olfml2b Retreg2
Intermittent access day 15 total locomotion	59283.24	2	1	14.3	0	1.00e+00	Olfml2b Retreg2
Intermittent access total locomotion	244.2	3	1	14.3	0	1.00e+00	Ndufb9 Olfml2b Retreg2
Intermittent access standard deviation	50481.83	3	1	14.3	1	5.26e-06	Foxred1 Olfml2b Retreg2
Cocaine induced anxiety	40087.44	3	2	28.6	-1	1.00e-04	Foxred1 Ndufb9 Retreg2
Post-drug Anxiety	6831.14	2	2	28.6	0	1.00e+00	Ndufb9 Retreg2
Baseline Anxiety	25905.75	3	2	28.6	1	1.44e-04	Foxred1 Ndufb9 Retreg2
Lifetime Intake	2284.48	3	1	14.3	0	1.00e+00	Foxred1 Olfml2b Retreg2
Incentive Sensitization - Responses	40906.11	3	2	28.6	-1	4.64e-04	Ndufb9 Olfml2b Retreg2
Incentive Sensitization - Breakpoint	28567.09	4	2	28.6	-1	1.78e-05	Foxred1 Ndufb9 Olfml2b Retreg2
Progressive ratio test 1 active lever presses	24974.52	3	1	14.3	1	1.26e-05	Ndufb9 Olfml2b Retreg2
Progressive ratio test 1 breakpoint	24068.54	3	1	14.3	1	7.81e-06	Ndufb9 Olfml2b Retreg2
Progressive ratio test 1 inactive lever presses	37783.74	3	2	28.6	1	2.02e-05	Foxred1 Ndufb9 Retreg2
Progressive ratio test 2 active lever presses	14311.13	3	1	14.3	-1	5.70e-04	Ndufb9 Olfml2b Retreg2
Progressive ratio test 2 breakpoint	11663.61	2	1	14.3	0	1.00e+00	Olfml2b Retreg2
Progressive ratio test 2 inactive lever presses	41031.58	3	1	14.3	1	7.92e-05	Foxred1 Ndufb9 Retreg2
Total sessions with >9 infusions	3982.25	2	1	14.3	0	1.00e+00	Olfml2b Retreg2
Short access day 1 total inactive lever presses	16350.83	6	2	28.6	-1	3.33e-08	Adamts20 Foxred1 Ndufb9 Retreg2 Supt7l Zfp513
Short access day 10 total inactive lever presses	54291.22	3	1	14.3	1	1.43e-06	Olfml2b Retreg2 Supt7l
Short access day 1 total infusions	55743.29	1	1	14.3	0	1.00e+00	Retreg2
Short access day 10 total infusions	19082.24	3	2	28.6	-1	8.25e-04	Ndufb9 Olfml2b Retreg2
Short access total infusions	33946.03	1	1	14.3	0	1.00e+00	Retreg2
Short access day 1 locomotion	21026.86	3	2	28.6	1	1.60e-04	Foxred1 Ndufb9 Retreg2
Short access day 10 total locomotion	45410.22	3	3	42.9	1	1.54e-04	Foxred1 Olfml2b Retreg2
Short access total locomotion	13662.83	4	2	28.6	1	1.27e-05	Foxred1 Ndufb9 Olfml2b Retreg2
Compulsive drug intake	16369.56	3	2	28.6	-1	3.51e-04	Foxred1 Ndufb9 Retreg2
One hour access (0.3 mA shock)	3245.9	3	2	28.6	0	1.00e+00	Foxred1 Ndufb9 Retreg2
One hour access (shock baseline)	46761.25	2	1	14.3	0	1.00e+00	Foxred1 Retreg2
Number of responses in last shaping day	17101.72	2	1	14.3	0	1.00e+00	Foxred1 Retreg2
Context. condit. distance diff. score	970.59	1	1	14.3	0	1.00e+00	Retreg2
Locomotion velocity, session 1	4880.48	3	1	14.3	0	1.00e+00	Ndufb9 Retreg2 Zfp513
Locomotion distance, session 1	2212.45	2	1	14.3	0	1.00e+00	Retreg2 Zfp513
Locomotion velocity, session 2	9358	1	1	14.3	0	1.00e+00	Retreg2
Locomotion distance, session 2	2393.66	1	1	14.3	0	1.00e+00	Retreg2
Locomotion velocity, session 3	2332.53	1	1	14.3	0	1.00e+00	Retreg2
Locomotion distance, session 3	16615.78	1	1	14.3	0	1.00e+00	Retreg2
Stereotopy head waving bouts, day 3	5866.4	1	1	14.3	0	1.00e+00	Retreg2
Stereotopy head waving duration, day 3	12131.92	1	1	14.3	0	1.00e+00	Retreg2
Locomotion velocity, session 7	658.8	2	1	14.3	0	1.00e+00	Retreg2 Zfp513
Locomotion distance, session 7	1879.14	2	1	14.3	0	1.00e+00	Ndufb9 Retreg2
Stereotopy head waving bouts, day 7	5257.18	2	2	28.6	0	1.00e+00	Ndufb9 Retreg2
Stereotopy head waving duration, day 7	4446.48	2	2	28.6	0	1.00e+00	Ndufb9 Retreg2
Locomotion velocity, session 8	1892.98	1	1	14.3	0	1.00e+00	Retreg2
Locomotion distance, session 8	673.32	1	1	14.3	0	1.00e+00	Retreg2
Degree of sensitization distance	15309.16	1	1	14.3	0	1.00e+00	Retreg2
Degree of sensitization stereotypy	4256.13	2	1	14.3	0	1.00e+00	Ndufb9 Retreg2
Condit. Reinf. active minus inactive responses	2064.24	2	1	14.3	0	1.00e+00	Adamts20 Retreg2
Condit. Reinf. active-inactive response ratio	553.1	2	1	14.3	0	1.00e+00	Adamts20 Retreg2
Condit. Reinf. active responses	5837.37	2	1	14.3	0	1.00e+00	Adamts20 Retreg2
Condit. Reinf. inactive responses	9694.1	2	1	14.3	0	1.00e+00	Ndufb9 Retreg2
Incentive salience index mean	14781.83	1	1	14.3	0	1.00e+00	Retreg2
Condit. Reinf. lever presses	21433.81	1	1	14.3	0	1.00e+00	Retreg2
Time in familiar zone, hab. session 1	20942.04	1	1	14.3	0	1.00e+00	Retreg2
Time in novel zone, hab. session 1	17764.8	1	1	14.3	0	1.00e+00	Retreg2
Total zone transitions, hab. session 1	916.07	2	1	14.3	0	1.00e+00	Ndufb9 Retreg2
Total locomotion distance, hab. session 1	1687	1	1	14.3	0	1.00e+00	Retreg2
Locomotion velocity, hab. session 1	1131.06	1	1	14.3	0	1.00e+00	Retreg2
Time in familiar zone, hab. session 2	23379.25	1	1	14.3	0	1.00e+00	Retreg2
Time in novel zone, hab. session 2	12466.52	1	1	14.3	0	1.00e+00	Retreg2
Total zone transitions, hab. session 2	143.96	2	1	14.3	0	1.00e+00	Ndufb9 Retreg2
Total locomotion distance, hab. session 2	96.8	1	1	14.3	0	1.00e+00	Retreg2
Locomotion velocity, hab. session 2	145.53	1	1	14.3	0	1.00e+00	Retreg2
Novel to familiar place preference ratio	27757.41	1	1	14.3	0	1.00e+00	Retreg2
Novelty place preference	54383.96	1	1	14.3	0	1.00e+00	Retreg2
Time in novel zone, NPP test	40844.77	1	1	14.3	0	1.00e+00	Retreg2
Total zone transitions, NPP test	4127.68	2	2	28.6	0	1.00e+00	Ndufb9 Retreg2
Total locomotion distance, NPP test	7114	1	1	14.3	0	1.00e+00	Retreg2
Locomotion velocity, NPP test	4041.22	1	1	14.3	0	1.00e+00	Retreg2
Pavlov. Cond. lever latency	2195.61	1	1	14.3	0	1.00e+00	Retreg2
Pavlov. Cond. change in total contacts	4539.35	1	1	14.3	0	1.00e+00	Retreg2
Pavlov. Cond. index score	1769.33	1	1	14.3	0	1.00e+00	Retreg2
Pavlov. Cond. latency score	1841.19	1	1	14.3	0	1.00e+00	Retreg2
Pavlov. Cond. lever contacts	1520.48	2	1	14.3	0	1.00e+00	Ndufb9 Retreg2
Pavlov. Cond. magazine entry number	2162.19	1	1	14.3	0	1.00e+00	Retreg2
Pavlov. Cond. intertrial magazine entries	182.85	3	1	14.3	0	1.00e+00	Ndufb9 Olfml2b Retreg2
Pavlov. Cond. lever-magazine prob. diff.	1940.27	1	1	14.3	0	1.00e+00	Retreg2
Pavlov. Cond. response bias	2606.99	1	1	14.3	0	1.00e+00	Retreg2
Bone: apparent density	5572.22	4	1	14.3	1	1.14e-04	Ndufb9 Retreg2 Supt7l Zfp513
Bone surface	8378.88	3	1	14.3	0	1.00e+00	Retreg2 Supt7l Zfp513
Bone volume	11280.75	3	1	14.3	0	1.00e+00	Retreg2 Supt7l Zfp513
Bone: connectivity density	2373.39	3	1	14.3	0	1.00e+00	Ndufb9 Retreg2 Supt7l
Bone: cortical apparent density	22636.78	2	1	14.3	0	1.00e+00	Ndufb9 Retreg2
Bone: cortical area	9468.26	2	1	14.3	0	1.00e+00	Ndufb9 Retreg2
Bone: cortical porosity	923.93	2	1	14.3	0	1.00e+00	Ndufb9 Retreg2
Bone: cortical porosity	2407.81	2	1	14.3	0	1.00e+00	Ndufb9 Retreg2
Bone: cortical thickness	817.52	2	1	14.3	0	1.00e+00	Ndufb9 Retreg2
Bone: cortical thickness	6100.69	2	1	14.3	0	1.00e+00	Ndufb9 Retreg2
Bone: cortical tissue density	24230.71	2	1	14.3	0	1.00e+00	Ndufb9 Retreg2
Bone: elastic displacement	14817.48	1	1	14.3	0	1.00e+00	Retreg2
Bone: elastic work	1494.59	1	1	14.3	0	1.00e+00	Retreg2
Bone: endosteal estimation	17631.97	2	1	14.3	0	1.00e+00	Ndufb9 Retreg2
Bone: endosteal perimeter	22350.62	1	1	14.3	0	1.00e+00	Retreg2
Bone: final force	7031.22	1	1	14.3	0	1.00e+00	Retreg2
Bone: final moment	1042.62	1	1	14.3	0	1.00e+00	Retreg2
Bone: marrow area	18537.3	2	1	14.3	0	1.00e+00	Ndufb9 Retreg2
Bone: maximum diameter	12203.48	2	1	14.3	0	1.00e+00	Ndufb9 Retreg2
Bone: maximum force	34553.99	1	1	14.3	0	1.00e+00	Retreg2
Bone: maximum moment	24715.64	1	1	14.3	0	1.00e+00	Retreg2
Bone: minimum diameter	17196.64	1	1	14.3	0	1.00e+00	Retreg2
Bone: periosteal estimation	38190.5	1	1	14.3	0	1.00e+00	Retreg2
Bone: periosteal perimeter	43183.28	1	1	14.3	0	1.00e+00	Retreg2
Bone: post-yield work	50847.58	1	1	14.3	0	1.00e+00	Retreg2
Bone: stiffness	35564.91	1	1	14.3	0	1.00e+00	Retreg2
Bone: tissue strength	12264.67	1	1	14.3	0	1.00e+00	Retreg2
Bone: trabecular number	10294.74	4	2	28.6	1	1.41e-04	Ndufb9 Retreg2 Supt7l Zfp513
Bone: trabecular spacing	10438.84	3	2	28.6	0	1.00e+00	Ndufb9 Retreg2 Zfp513
Bone: trabecular thickness	33264.33	1	1	14.3	0	1.00e+00	Retreg2
Bone: trabecular tissue density	26819.64	2	2	28.6	0	1.00e+00	Ndufb9 Retreg2
Breakpoint value in progressive ratio session	56219.08	1	1	14.3	0	1.00e+00	Retreg2
Distance traveled before self-admin	33510.04	3	1	14.3	1	2.20e-04	Foxred1 Ndufb9 Retreg2
Distance traveled after self-admin	50416.54	2	1	14.3	0	1.00e+00	Foxred1 Retreg2
Delta time in closed arm before/after self-admin	436.07	3	1	14.3	0	1.00e+00	Foxred1 Ndufb9 Retreg2
Delta time in open arm before/after self-admin	18278	2	1	14.3	0	1.00e+00	Olfml2b Retreg2
Diff in mean of infusions in LGA sessions	27129.46	3	1	14.3	-1	4.57e-04	Ndufb9 Olfml2b Retreg2
Extinction: sum of active levers before priming	22908.91	3	3	42.9	1	4.24e-04	Foxred1 Ndufb9 Retreg2
Active lever presses in extinction session 6	1565.95	2	1	14.3	0	1.00e+00	Foxred1 Retreg2
Delta distance traveled before/after self-admin	3120.28	3	2	28.6	-1	1.16e-03	Foxred1 Ndufb9 Retreg2
Delta ambulatory time before/after self-admin	24018.47	3	1	14.3	-1	2.92e-04	Foxred1 Ndufb9 Retreg2
Time in closed arm before self-admin	44122	2	1	14.3	0	1.00e+00	Foxred1 Retreg2
Time in closed arm after self-admin	19471.75	1	1	14.3	0	1.00e+00	Retreg2
Time in open arm before self-admin	11553.28	2	2	28.6	0	1.00e+00	Ndufb9 Retreg2
Time in open arm after self-admin	648.74	3	2	28.6	0	1.00e+00	Foxred1 Ndufb9 Retreg2
Sum of active levers in priming session hrs 5-6	1302.98	3	1	14.3	0	1.00e+00	Ndufb9 Olfml2b Retreg2
Time to tail flick, vehicle, before self-admin	12839.79	3	1	14.3	1	2.97e-04	Foxred1 Ndufb9 Retreg2
Time to tail flick, vehicle, after self-admin	23666.74	4	1	14.3	1	1.23e-05	Foxred1 Ndufb9 Retreg2 Supt7l
Time to tail flick, test, before self-admin	10951.88	3	2	28.6	0	1.00e+00	Foxred1 Ndufb9 Retreg2
Time to tail flick, test, after self-admin	1972.14	3	2	28.6	0	1.00e+00	Foxred1 Ndufb9 Retreg2
Delta time to tail flick, vehicle, before/after SA	18274.05	1	1	14.3	0	1.00e+00	Retreg2
Delta time to tail flick, test, before/after SA	28421.46	2	1	14.3	0	1.00e+00	Ndufb9 Retreg2
Ambulatory time before self-admin	57036.35	2	2	28.6	0	1.00e+00	Foxred1 Retreg2
Ambulatory time after self-admin	88230.17	1	1	14.3	0	1.00e+00	Retreg2
Total heroin consumption	332.3	3	2	28.6	0	1.00e+00	Foxred1 Olfml2b Retreg2
Area under the delay curve	27209.42	2	1	14.3	0	1.00e+00	Olfml2b Retreg2
Delay disc. indifference point, 0s delay	4744.55	2	1	14.3	0	1.00e+00	Olfml2b Retreg2
Delay disc. indifference point, 16s delay	24938.82	2	1	14.3	0	1.00e+00	Olfml2b Retreg2
Delay disc. indifference point, 2s delay	825.84	1	1	14.3	0	1.00e+00	Retreg2
Delay disc. indifference point, 24s delay	25001.74	3	1	14.3	-1	2.52e-05	Olfml2b Retreg2 Zfp513
Delay disc. indifference point, 4s delay	852.87	3	1	14.3	0	1.00e+00	Ndufb9 Olfml2b Retreg2
Delay disc. indifference point, 8s delay	50718.73	1	1	14.3	0	1.00e+00	Retreg2
Delay discount exponential model param	20079.06	2	1	14.3	0	1.00e+00	Olfml2b Retreg2
Delay discount hyperbolic model param	15246.89	2	1	14.3	0	1.00e+00	Olfml2b Retreg2
Fecal boli incidents, locomotor time 1	50059.8	2	1	14.3	0	1.00e+00	Olfml2b Retreg2
Change in fecal boli incidents, locomotor task	7839.87	3	2	28.6	0	1.00e+00	Adamts20 Ndufb9 Retreg2
Time >=10cm from walls, locomotor time 1	12320.09	3	1	14.3	-1	2.37e-04	Olfml2b Retreg2 Zfp513
Bouts of movement, locomotor time 1	41590.88	1	1	14.3	0	1.00e+00	Retreg2
Total resting periods, locomotor time 1	11802.64	1	1	14.3	0	1.00e+00	Retreg2
Rest time, locomotor task time 1	25323.74	2	1	14.3	0	1.00e+00	Ndufb9 Retreg2
Distance moved, locomotor task time 1	53110.62	2	2	28.6	0	1.00e+00	Ndufb9 Retreg2
Vertical activity count, locomotor time 1	109540.42	1	1	14.3	0	1.00e+00	Retreg2
Time >=10cm from walls, locomotor time 2	53999.77	2	1	14.3	0	1.00e+00	Olfml2b Retreg2
Bouts of movement, locomotor time 2	43579.59	3	1	14.3	1	3.80e-06	Foxred1 Olfml2b Retreg2
Total resting periods, locomotor time 2	47525.09	3	1	14.3	1	6.17e-06	Foxred1 Olfml2b Retreg2
Rest time, locomotor task time 2	20949.63	3	1	14.3	-1	4.89e-04	Ndufb9 Olfml2b Retreg2
Distance moved, locomotor task time 2	34268.85	1	1	14.3	0	1.00e+00	Retreg2
Vertical activity count, locomotor time 2	69210.42	1	1	14.3	0	1.00e+00	Retreg2
Weight adjusted by age	54002.71	2	2	28.6	0	1.00e+00	Ndufb9 Retreg2
Seeking ratio, delayed vs. immediate footshock	24701.66	2	1	14.3	0	1.00e+00	Retreg2 Zfp513
Locomotion in novel chamber	5463.41	3	2	28.6	0	1.00e+00	Ndufb9 Olfml2b Retreg2
Locomotion in novel chamber post-restriction	51551.86	2	1	14.3	0	1.00e+00	Ndufb9 Retreg2
Progressive ratio	52642.08	2	2	28.6	0	1.00e+00	Ndufb9 Retreg2
Food seeking constrained by brief footshock	2451.14	3	1	14.3	0	1.00e+00	Ndufb9 Retreg2 Zfp513
Seeking ratio, punishment vs. effort	39433.52	2	2	28.6	0	1.00e+00	Ndufb9 Retreg2
Run reversals in cocaine runway, females	12400.31	3	1	14.3	0	1.00e+00	Foxred1 Olfml2b Retreg2
Run reversals in cocaine runway, males	5998.06	4	2	28.6	1	5.37e-05	Foxred1 Ndufb9 Retreg2 Zfp513
Latency to leave start box in cocaine runway	29292.5	2	1	14.3	0	1.00e+00	Olfml2b Retreg2
Latency to leave start box in cocaine runway, F	9470.12	3	2	28.6	0	1.00e+00	Ndufb9 Olfml2b Retreg2
Latency to leave start box in cocaine runway, M	2389.19	3	1	14.3	0	1.00e+00	Foxred1 Ndufb9 Retreg2
Co content in liver	4721.74	1	1	14.3	0	1.00e+00	Retreg2
Cu content in liver	89.33	2	1	14.3	0	1.00e+00	Ndufb9 Retreg2
Fe content in liver	5656.2	1	1	14.3	0	1.00e+00	Retreg2
K content in liver	3300.88	2	1	14.3	0	1.00e+00	Retreg2 Zfp513
Mg content in liver	12254.82	2	1	14.3	0	1.00e+00	Olfml2b Retreg2
Mn content in liver	1483.73	3	2	28.6	0	1.00e+00	Ndufb9 Olfml2b Retreg2
Na content in liver	5552.69	3	1	14.3	0	1.00e+00	Ndufb9 Olfml2b Retreg2
Rb content in liver	241.33	2	2	28.6	0	1.00e+00	Ndufb9 Retreg2
Se content in liver	7.92	2	0	0	0	1.00e+00	Ndufb9 Olfml2b
Zn content in liver	7891.81	2	2	28.6	0	1.00e+00	Ndufb9 Retreg2

Associations by panel

Tissue	RNA modality	# hits	% hits/tests	Avg chisq
Adipose	alternative polyA	0	0	1.04
Adipose	alternative TSS	0	0	1.03
Adipose	gene expression	0	0	1.05
Adipose	isoform ratio	0	0	1.05
Adipose	intron excision ratio	0	0	1.08
Adipose	mRNA stability	1	0	1.12
BLA	alternative polyA	0	0	1.06
BLA	alternative TSS	0	0	0.99
BLA	gene expression	0	0	1.04
BLA	isoform ratio	0	0	1.07
BLA	intron excision ratio	0	0	1.04
BLA	mRNA stability	0	0	1.08
Brain	alternative polyA	0	0	1.07
Brain	alternative TSS	0	0	1.04
Brain	gene expression	0	0	1.04
Brain	isoform ratio	0	0	1.06
Brain	intron excision ratio	0	0	1.05
Brain	mRNA stability	1	0	1.09
Eye	alternative polyA	0	0	1.07
Eye	alternative TSS	0	0	0.81
Eye	gene expression	0	0	1.02
Eye	isoform ratio	0	0	1.01
Eye	intron excision ratio	0	0	1.04
Eye	mRNA stability	0	0	1.13
IC	alternative polyA	0	0	1.14
IC	alternative TSS	0	0	1.02
IC	gene expression	1	0	1.05
IC	isoform ratio	0	0	1.1
IC	intron excision ratio	0	0	1.06
IC	mRNA stability	0	0	1.04
IL	alternative polyA	0	0	1.09
IL	alternative TSS	0	0	1.1
IL	gene expression	1	0	1.05
IL	isoform ratio	0	0	1.1
IL	intron excision ratio	0	0	0.99
IL	mRNA stability	0	0	1.08
LHb	alternative polyA	0	0	1.16
LHb	alternative TSS	0	0	1.06
LHb	gene expression	0	0	1.06
LHb	isoform ratio	0	0	1.08
LHb	intron excision ratio	0	0	0.97
LHb	mRNA stability	0	0	1.13
Liver	alternative polyA	0	0	1.07
Liver	alternative TSS	0	0	1.1
Liver	gene expression	0	0	1.05
Liver	isoform ratio	0	0	1.07
Liver	intron excision ratio	0	0	1.1
Liver	mRNA stability	0	0	1.07
NAcc	alternative polyA	2	0.1	315.22
NAcc	alternative TSS	0	0	1.08
NAcc	gene expression	0	0	1.05
NAcc	isoform ratio	0	0	1.06
NAcc	intron excision ratio	1	0	1.1
NAcc	mRNA stability	0	0	1.07
OFC	alternative polyA	0	0	1.03
OFC	alternative TSS	0	0	1.13
OFC	gene expression	0	0	1.02
OFC	isoform ratio	0	0	1.12
OFC	intron excision ratio	0	0	0.97
OFC	mRNA stability	0	0	1.01
PL	alternative polyA	0	0	1.13
PL	alternative TSS	0	0	1.01
PL	gene expression	1	0	1.05
PL	isoform ratio	0	0	1.06
PL	intron excision ratio	0	0	1.05
PL	mRNA stability	0	0	1.06
pVTA	alternative polyA	0	0	1.1
pVTA	alternative TSS	0	0	1.07
pVTA	gene expression	0	0	1.04
pVTA	isoform ratio	0	0	1.07
pVTA	intron excision ratio	0	0	1.08
pVTA	mRNA stability	0	0	1.1
RMTg	alternative polyA	0	0	1.11
RMTg	alternative TSS	0	0	1.07
RMTg	gene expression	0	0	1.09
RMTg	isoform ratio	0	0	1.21
RMTg	intron excision ratio	0	0	1.06
RMTg	mRNA stability	0	0	1.04