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Intermitt. access day 15 inactive lever presses

Intermittent access day 15 total inactive lever presses

Tags: Behavior · Intermittent access · Cocaine

Project: p50_paul_meyer_2020

6 loci · 6 genes with independent associations · 7 total associated genes

Significant Loci

#	Chr	Start pos	End pos	# assoc genes	# joint models	Best TWAS P	Best GWAS P	Cond GWAS P	Joint genes
1	chr6	29955132	31350622	1	1	4.73e-08	9.83e-04	1.00e+00	Supt7l
2	chr7	92127461	93066096	1	1	5.14e-59	4.13e-01	1.00e+00	Ndufb9
3	chr7	126707686	128105211	1	1	8.58e-09	1.96e-04	9.02e-01	Adamts20
4	chr8	41432021	42517271	1	1	5.60e-19	2.88e-01	6.77e-09	Foxred1
5	chr9	83390749	84777604	2	1	0.00e+00	1.08e-01	1.00e+00	Retreg2
6	chr13	84702566	86100919	1	1	8.54e-09	2.17e-01	4.22e-34	Olfml2b

Pleiotropic Associations

Trait	Chi2 ratio	# genes+	# genes++	% genes++	Corr	Corr P	Genes
BMI with tail	221.88	4	2	33.3	-0.99	1.13e-02	Foxred1 Ndufb9 Olfml2b Retreg2
BMI without tail	14321.26	3	2	33.3	1	4.41e-04	Ndufb9 Olfml2b Retreg2
Body weight	5.98	4	1	16.7	-0.23	7.74e-01	Ndufb9 Olfml2b Retreg2 Supt7l
Epididymis fat weight	9078.13	3	2	33.3	1	9.24e-04	Ndufb9 Retreg2 Supt7l
Glucose	273.97	2	1	16.7	0	1.00e+00	Ndufb9 Retreg2
Heart weight	1536.76	2	1	16.7	0	1.00e+00	Ndufb9 Retreg2
Left kidney weight	11014.31	4	2	33.3	-1	4.07e-05	Foxred1 Ndufb9 Olfml2b Retreg2
Right kidney weight	10105.34	3	2	33.3	-1	9.97e-04	Foxred1 Ndufb9 Retreg2
Tail length	14468.02	1	1	16.7	0	1.00e+00	Retreg2
Length with tail	300.47	4	2	33.3	1	2.32e-04	Foxred1 Ndufb9 Retreg2 Supt7l
Length without tail	15749.56	2	1	16.7	0	1.00e+00	Ndufb9 Retreg2
Liver weight, left	1747.19	2	1	16.7	0	1.00e+00	Ndufb9 Retreg2
Liver weight, right	26.54	2	1	16.7	0	1.00e+00	Ndufb9 Retreg2
Parametrial fat weight	92.67	2	1	16.7	0	1.00e+00	Foxred1 Retreg2
Retroperitoneal fat weight	1319.4	2	2	33.3	0	1.00e+00	Retreg2 Supt7l
Intraocular pressure	3466.83	2	1	16.7	0	1.00e+00	Retreg2 Supt7l
Extensor digitorum longus weight	540.03	2	1	16.7	0	1.00e+00	Retreg2 Supt7l
Soleus weight	7.34	5	1	16.7	0.77	1.25e-01	Adamts20 Ndufb9 Olfml2b Retreg2 Supt7l
Tibialis anterior weight	387.99	3	1	16.7	0	1.00e+00	Olfml2b Retreg2 Supt7l
Tibia length	258.12	3	1	16.7	0	1.00e+00	Adamts20 Ndufb9 Retreg2
Number of licking bursts	33719.1	1	1	16.7	0	1.00e+00	Retreg2
Food consumed during 24 hour testing period	17758.05	1	1	16.7	0	1.00e+00	Retreg2
Times rat made contact with spout	41.61	2	1	16.7	0	1.00e+00	Ndufb9 Retreg2
Mean time between licks in bursts	37213.79	2	1	16.7	0	1.00e+00	Ndufb9 Retreg2
Mean num. licks in bursts	28381.96	1	1	16.7	0	1.00e+00	Retreg2
Std. dev. time between licks in bursts	29750.31	1	1	16.7	0	1.00e+00	Retreg2
Water consumed over 24 hours	17088.15	1	1	16.7	0	1.00e+00	Retreg2
Patch foraging indifference point 0 sec	39171.5	1	1	16.7	0	1.00e+00	Retreg2
Patch foraging indifference point AUC	16718.88	2	1	16.7	0	1.00e+00	Ndufb9 Retreg2
Indifference point function ln k	13929.95	3	2	33.3	1	6.55e-06	Ndufb9 Olfml2b Retreg2
Indifference point function log k	13929.95	3	2	33.3	1	6.55e-06	Ndufb9 Olfml2b Retreg2
Patch foraging total patch changes 0 sec	41947.04	1	1	16.7	0	1.00e+00	Retreg2
Patch foraging total patch changes 12 sec	785.2	3	2	33.3	0	1.00e+00	Foxred1 Ndufb9 Retreg2
Patch foraging total patch changes 18 sec	20233.2	2	1	16.7	0	1.00e+00	Ndufb9 Retreg2
Patch foraging total patch changes 24 sec	24967.63	2	2	33.3	0	1.00e+00	Ndufb9 Retreg2
Patch foraging total patch changes 6 sec	3903.01	2	2	33.3	0	1.00e+00	Ndufb9 Retreg2
Patch foraging time to switch 0 sec	16633.49	3	2	33.3	1	1.83e-03	Ndufb9 Olfml2b Retreg2
Patch foraging water rate 0 sec	15113.53	3	1	16.7	-1	1.58e-03	Ndufb9 Olfml2b Retreg2
Patch foraging water rate 12 sec	35328.83	1	1	16.7	0	1.00e+00	Retreg2
Patch foraging water rate 18 sec	16866.98	2	1	16.7	0	1.00e+00	Ndufb9 Retreg2
Patch foraging water rate 24 sec	520.56	2	1	16.7	0	1.00e+00	Retreg2 Supt7l
Patch foraging water rate 6 sec	435.09	2	2	33.3	0	1.00e+00	Ndufb9 Retreg2
Locomotor activity	8.9	1	0	0	0	1.00e+00	Foxred1
Locomotor testing distance	6925.58	3	1	16.7	-1	7.34e-04	Foxred1 Ndufb9 Retreg2
Locomotor testing rearing	15859.68	3	1	16.7	-1	4.27e-04	Foxred1 Ndufb9 Retreg2
Light reinforcement 1	22113.11	2	1	16.7	0	1.00e+00	Retreg2 Supt7l
Light reinforcement 2	7353.78	4	1	16.7	-1	1.04e-04	Ndufb9 Olfml2b Retreg2 Supt7l
Reaction time number correct	15877.91	3	2	33.3	-1	1.83e-03	Ndufb9 Olfml2b Retreg2
Reaction time mean minus median	29996.3	3	1	16.7	1	1.13e-03	Ndufb9 Olfml2b Retreg2
Reaction time mean minus median AUC	31008.72	3	2	33.3	1	1.29e-03	Ndufb9 Olfml2b Retreg2
Reaction time num false alarms	15357.42	1	1	16.7	0	1.00e+00	Retreg2
Reaction time num false alarms AUC	17511.01	1	1	16.7	0	1.00e+00	Retreg2
Reaction time trials correct on left	15877.91	3	2	33.3	-1	1.83e-03	Ndufb9 Olfml2b Retreg2
Reaction time trials on left	15230.5	3	2	33.3	-1	1.83e-03	Ndufb9 Olfml2b Retreg2
Reaction time mean	14869.21	1	1	16.7	0	1.00e+00	Retreg2
Reaction time mean AUC	19391.48	1	1	16.7	0	1.00e+00	Retreg2
Median of all reaction times	3951.2	1	1	16.7	0	1.00e+00	Retreg2
Reaction time omissions	4186.04	2	1	16.7	0	1.00e+00	Ndufb9 Retreg2
Reaction time false alarm rate	108.16	2	1	16.7	0	1.00e+00	Ndufb9 Retreg2
Reaction time premature initiation rate	9733.76	1	1	16.7	0	1.00e+00	Retreg2
Reaction time premature initiations	26876.79	1	1	16.7	0	1.00e+00	Retreg2
Std. dev. reaction times	15223.47	3	1	16.7	1	1.33e-03	Ndufb9 Olfml2b Retreg2
Reaction time trials completed	15230.5	3	2	33.3	-1	1.83e-03	Ndufb9 Olfml2b Retreg2
Reaction time trials AUC	15541.26	3	1	16.7	-1	1.72e-03	Ndufb9 Olfml2b Retreg2
Social response proportion	8777.03	1	1	16.7	0	1.00e+00	Retreg2
Social responses	635.8	2	1	16.7	0	1.00e+00	Ndufb9 Retreg2
Social time	11650.06	1	1	16.7	0	1.00e+00	Retreg2
Conditioned locomotion	1400.08	1	1	16.7	0	1.00e+00	Retreg2
Cocaine response after cond. corrected	9573.48	1	1	16.7	0	1.00e+00	Retreg2
Cocaine response after cond. not corrected	9294.65	1	1	16.7	0	1.00e+00	Retreg2
Cocaine response before conditioning	655.41	1	1	16.7	0	1.00e+00	Retreg2
Saline control response	3160.68	1	1	16.7	0	1.00e+00	Retreg2
Condit. Reinf. active minus inactive responses	14521.56	1	1	16.7	0	1.00e+00	Retreg2
Condit. Reinf. active-inactive response ratio	14360.59	2	1	16.7	0	1.00e+00	Ndufb9 Retreg2
Condit. Reinf. active responses	2302.04	1	1	16.7	0	1.00e+00	Retreg2
Condit. Reinf. inactive responses	10889.7	1	1	16.7	0	1.00e+00	Retreg2
Condit. Reinf. lever presses	1935.17	2	1	16.7	0	1.00e+00	Ndufb9 Retreg2
Condit. Reinf. lever reinforcers received	469.54	1	1	16.7	0	1.00e+00	Retreg2
Pavlov. Cond. lever latency	2531.81	1	1	16.7	0	1.00e+00	Retreg2
Pavlov. Cond. magazine entry latency	13282.18	1	1	16.7	0	1.00e+00	Retreg2
Pavlov. Cond. change in total contacts	13274.44	2	1	16.7	0	1.00e+00	Ndufb9 Retreg2
Pavlov. Cond. index score	12744.53	1	1	16.7	0	1.00e+00	Retreg2
Pavlov. Cond. latency score	16150.81	1	1	16.7	0	1.00e+00	Retreg2
Pavlov. Cond. lever contacts	5331.08	1	1	16.7	0	1.00e+00	Retreg2
Pavlov. Cond. magazine entry number	4012.39	1	1	16.7	0	1.00e+00	Retreg2
Pavlov. Cond. intertrial magazine entries	17498.16	1	1	16.7	0	1.00e+00	Retreg2
Pavlov. Cond. lever-magazine prob. diff.	11800.43	1	1	16.7	0	1.00e+00	Retreg2
Pavlov. Cond. response bias	1164.95	1	1	16.7	0	1.00e+00	Retreg2
Conditioned reinforcement - actives	25216.05	3	2	33.3	1	8.80e-05	Ndufb9 Olfml2b Retreg2
Conditioned reinforcement - inactives	10825.76	5	2	33.3	1	9.98e-10	Foxred1 Ndufb9 Olfml2b Retreg2 Supt7l
Conditioned locomotion	2606.8	4	2	33.3	1	3.36e-03	Foxred1 Ndufb9 Olfml2b Retreg2
Intermittent access intake day 1-15 change	31983.4	3	2	33.3	1	1.45e-05	Foxred1 Olfml2b Retreg2
Intermittent access intake escalation	31542.92	3	2	33.3	1	4.22e-06	Foxred1 Olfml2b Retreg2
Intermittent access intake escalation 2	12099.58	3	2	33.3	0	1.00e+00	Foxred1 Olfml2b Retreg2
Intermitt. access day 1 inactive lever presses	45163.21	3	1	16.7	1	4.55e-04	Ndufb9 Olfml2b Retreg2
Intermitt. access escalation Index	23332.96	3	1	16.7	-1	8.89e-04	Ndufb9 Olfml2b Retreg2
Intermittent access day 1 total infusions	13230.88	4	1	16.7	-1	1.25e-05	Foxred1 Olfml2b Retreg2 Supt7l
Intermittent access day 15 total infusions	12203.62	3	3	50	1	2.15e-04	Foxred1 Olfml2b Retreg2
Intermittent access terminal intake (last 3 days)	8291.07	3	3	50	0	1.00e+00	Foxred1 Olfml2b Retreg2
Intermittent access total infusions	71.16	3	1	16.7	0	1.00e+00	Foxred1 Olfml2b Retreg2
Intermittent access day 1 locomotion	8751.28	3	2	33.3	-1	7.05e-04	Foxred1 Olfml2b Retreg2
Intermittent access day 15 total locomotion	28520.98	2	1	16.7	0	1.00e+00	Olfml2b Retreg2
Intermittent access total locomotion	46.04	3	1	16.7	0	1.00e+00	Ndufb9 Olfml2b Retreg2
Intermittent access standard deviation	28498.83	3	1	16.7	1	8.05e-05	Foxred1 Olfml2b Retreg2
Cocaine induced anxiety	17303.26	3	2	33.3	-1	4.88e-04	Foxred1 Ndufb9 Retreg2
Post-drug Anxiety	2390.18	2	2	33.3	0	1.00e+00	Ndufb9 Retreg2
Baseline Anxiety	11238.15	3	2	33.3	0	1.00e+00	Foxred1 Ndufb9 Retreg2
Lifetime Intake	560.13	3	1	16.7	0	1.00e+00	Foxred1 Olfml2b Retreg2
Incentive Sensitization - Responses	17854.18	3	2	33.3	-1	2.11e-03	Ndufb9 Olfml2b Retreg2
Incentive Sensitization - Breakpoint	11067.11	4	2	33.3	-1	1.25e-04	Foxred1 Ndufb9 Olfml2b Retreg2
Progressive ratio test 1 active lever presses	8002.53	3	1	16.7	1	5.24e-05	Ndufb9 Olfml2b Retreg2
Progressive ratio test 1 breakpoint	7581.12	3	1	16.7	1	3.28e-05	Ndufb9 Olfml2b Retreg2
Progressive ratio test 1 inactive lever presses	15564.71	3	2	33.3	1	4.57e-05	Foxred1 Ndufb9 Retreg2
Progressive ratio test 2 active lever presses	3821.45	3	1	16.7	-1	2.64e-03	Ndufb9 Olfml2b Retreg2
Progressive ratio test 2 breakpoint	4276.31	2	1	16.7	0	1.00e+00	Olfml2b Retreg2
Progressive ratio test 2 inactive lever presses	18133.19	3	1	16.7	1	2.52e-04	Foxred1 Ndufb9 Retreg2
Total sessions with >9 infusions	985.9	2	1	16.7	0	1.00e+00	Olfml2b Retreg2
Short access day 1 total inactive lever presses	6581.21	5	2	33.3	-1	1.59e-05	Adamts20 Foxred1 Ndufb9 Retreg2 Supt7l
Short access day 10 total inactive lever presses	34721.14	3	1	16.7	1	7.13e-06	Olfml2b Retreg2 Supt7l
Short access day 1 total infusions	12798.94	2	1	16.7	0	1.00e+00	Foxred1 Retreg2
Short access day 10 total infusions	7579.34	3	2	33.3	0	1.00e+00	Ndufb9 Olfml2b Retreg2
Short access total infusions	8778.92	1	1	16.7	0	1.00e+00	Retreg2
Short access day 1 locomotion	8287.55	3	2	33.3	0	1.00e+00	Foxred1 Ndufb9 Retreg2
Short access day 10 total locomotion	22062.72	3	3	50	1	6.39e-04	Foxred1 Olfml2b Retreg2
Short access total locomotion	4682.52	4	2	33.3	1	1.08e-03	Foxred1 Ndufb9 Olfml2b Retreg2
Compulsive drug intake	6239.47	3	2	33.3	0	1.00e+00	Foxred1 Ndufb9 Retreg2
One hour access (0.3 mA shock)	799.8	3	2	33.3	0	1.00e+00	Foxred1 Ndufb9 Retreg2
One hour access (shock baseline)	18338.09	2	1	16.7	0	1.00e+00	Foxred1 Retreg2
Number of responses in last shaping day	4544.59	2	1	16.7	0	1.00e+00	Foxred1 Retreg2
Context. condit. distance diff. score	212.47	1	1	16.7	0	1.00e+00	Retreg2
Locomotion velocity, session 1	1769.63	2	1	16.7	0	1.00e+00	Ndufb9 Retreg2
Locomotion distance, session 1	1024.77	1	1	16.7	0	1.00e+00	Retreg2
Locomotion velocity, session 2	2158.08	1	1	16.7	0	1.00e+00	Retreg2
Locomotion distance, session 2	508.11	1	1	16.7	0	1.00e+00	Retreg2
Locomotion velocity, session 3	507.49	1	1	16.7	0	1.00e+00	Retreg2
Locomotion distance, session 3	4009.46	1	1	16.7	0	1.00e+00	Retreg2
Stereotopy head waving bouts, day 3	1361.96	1	1	16.7	0	1.00e+00	Retreg2
Stereotopy head waving duration, day 3	2872.44	1	1	16.7	0	1.00e+00	Retreg2
Locomotion velocity, session 7	292.79	1	1	16.7	0	1.00e+00	Retreg2
Locomotion distance, session 7	435.3	2	1	16.7	0	1.00e+00	Ndufb9 Retreg2
Stereotopy head waving bouts, day 7	1279.33	2	2	33.3	0	1.00e+00	Ndufb9 Retreg2
Stereotopy head waving duration, day 7	1081.37	2	2	33.3	0	1.00e+00	Ndufb9 Retreg2
Locomotion velocity, session 8	409.23	1	1	16.7	0	1.00e+00	Retreg2
Locomotion distance, session 8	147.88	1	1	16.7	0	1.00e+00	Retreg2
Degree of sensitization distance	3670.85	1	1	16.7	0	1.00e+00	Retreg2
Degree of sensitization stereotypy	1029.63	2	1	16.7	0	1.00e+00	Ndufb9 Retreg2
Condit. Reinf. active minus inactive responses	482.72	2	1	16.7	0	1.00e+00	Adamts20 Retreg2
Condit. Reinf. active-inactive response ratio	125.3	2	1	16.7	0	1.00e+00	Adamts20 Retreg2
Condit. Reinf. active responses	1387.93	2	1	16.7	0	1.00e+00	Adamts20 Retreg2
Condit. Reinf. inactive responses	2347.53	2	1	16.7	0	1.00e+00	Ndufb9 Retreg2
Incentive salience index mean	1773.38	2	1	16.7	0	1.00e+00	Adamts20 Retreg2
Condit. Reinf. lever presses	5282.33	1	1	16.7	0	1.00e+00	Retreg2
Time in familiar zone, hab. session 1	5589.03	1	1	16.7	0	1.00e+00	Retreg2
Time in novel zone, hab. session 1	9232.79	1	1	16.7	0	1.00e+00	Retreg2
Total zone transitions, hab. session 1	221.7	2	1	16.7	0	1.00e+00	Ndufb9 Retreg2
Total locomotion distance, hab. session 1	394.1	1	1	16.7	0	1.00e+00	Retreg2
Locomotion velocity, hab. session 1	266.96	1	1	16.7	0	1.00e+00	Retreg2
Time in familiar zone, hab. session 2	5880.03	1	1	16.7	0	1.00e+00	Retreg2
Time in novel zone, hab. session 2	6311.49	1	1	16.7	0	1.00e+00	Retreg2
Total zone transitions, hab. session 2	35.66	2	1	16.7	0	1.00e+00	Ndufb9 Retreg2
Total locomotion distance, hab. session 2	22.17	1	1	16.7	0	1.00e+00	Retreg2
Locomotion velocity, hab. session 2	31.27	1	1	16.7	0	1.00e+00	Retreg2
Novel to familiar place preference ratio	15339.58	1	1	16.7	0	1.00e+00	Retreg2
Novelty place preference	14927.56	1	1	16.7	0	1.00e+00	Retreg2
Time in novel zone, NPP test	10685.62	1	1	16.7	0	1.00e+00	Retreg2
Total zone transitions, NPP test	980.79	2	2	33.3	0	1.00e+00	Ndufb9 Retreg2
Total locomotion distance, NPP test	1687.31	1	1	16.7	0	1.00e+00	Retreg2
Locomotion velocity, NPP test	953.07	1	1	16.7	0	1.00e+00	Retreg2
Pavlov. Cond. lever latency	491.79	1	1	16.7	0	1.00e+00	Retreg2
Pavlov. Cond. change in total contacts	1037.76	1	1	16.7	0	1.00e+00	Retreg2
Pavlov. Cond. index score	384.43	1	1	16.7	0	1.00e+00	Retreg2
Pavlov. Cond. latency score	404.63	1	1	16.7	0	1.00e+00	Retreg2
Pavlov. Cond. lever contacts	344.19	2	1	16.7	0	1.00e+00	Ndufb9 Retreg2
Pavlov. Cond. magazine entry number	491.61	1	1	16.7	0	1.00e+00	Retreg2
Pavlov. Cond. intertrial magazine entries	49.48	3	1	16.7	0	1.00e+00	Ndufb9 Olfml2b Retreg2
Pavlov. Cond. lever-magazine prob. diff.	418.89	1	1	16.7	0	1.00e+00	Retreg2
Pavlov. Cond. response bias	583.93	1	1	16.7	0	1.00e+00	Retreg2
Bone: apparent density	1826.24	3	1	16.7	0	1.00e+00	Ndufb9 Retreg2 Supt7l
Bone surface	3101.53	2	1	16.7	0	1.00e+00	Retreg2 Supt7l
Bone volume	4315.08	2	1	16.7	0	1.00e+00	Retreg2 Supt7l
Bone: connectivity density	563.19	3	1	16.7	0	1.00e+00	Ndufb9 Retreg2 Supt7l
Bone: cortical apparent density	6014.36	2	1	16.7	0	1.00e+00	Ndufb9 Retreg2
Bone: cortical area	2293.91	2	1	16.7	0	1.00e+00	Ndufb9 Retreg2
Bone: cortical porosity	221.79	2	1	16.7	0	1.00e+00	Ndufb9 Retreg2
Bone: cortical porosity	560.57	2	1	16.7	0	1.00e+00	Ndufb9 Retreg2
Bone: cortical thickness	191.17	2	1	16.7	0	1.00e+00	Ndufb9 Retreg2
Bone: cortical thickness	1464.97	2	1	16.7	0	1.00e+00	Ndufb9 Retreg2
Bone: cortical tissue density	6505.97	2	1	16.7	0	1.00e+00	Ndufb9 Retreg2
Bone: elastic displacement	3805.7	1	1	16.7	0	1.00e+00	Retreg2
Bone: elastic work	361.86	1	1	16.7	0	1.00e+00	Retreg2
Bone: endosteal estimation	4460.13	2	1	16.7	0	1.00e+00	Ndufb9 Retreg2
Bone: endosteal perimeter	11863.6	1	1	16.7	0	1.00e+00	Retreg2
Bone: final force	1600.36	1	1	16.7	0	1.00e+00	Retreg2
Bone: final moment	219.15	1	1	16.7	0	1.00e+00	Retreg2
Bone: marrow area	4718.77	2	1	16.7	0	1.00e+00	Ndufb9 Retreg2
Bone: maximum diameter	3037.24	2	1	16.7	0	1.00e+00	Ndufb9 Retreg2
Bone: maximum force	8697.09	1	1	16.7	0	1.00e+00	Retreg2
Bone: maximum moment	5989.29	1	1	16.7	0	1.00e+00	Retreg2
Bone: minimum diameter	4100.86	1	1	16.7	0	1.00e+00	Retreg2
Bone: periosteal estimation	9791.57	1	1	16.7	0	1.00e+00	Retreg2
Bone: periosteal perimeter	11400.25	1	1	16.7	0	1.00e+00	Retreg2
Bone: post-yield work	13672.98	1	1	16.7	0	1.00e+00	Retreg2
Bone: stiffness	9032.86	1	1	16.7	0	1.00e+00	Retreg2
Bone: tissue strength	2995.95	1	1	16.7	0	1.00e+00	Retreg2
Bone: trabecular number	3593.56	3	2	33.3	0	1.00e+00	Ndufb9 Retreg2 Supt7l
Bone: trabecular spacing	3988.39	2	2	33.3	0	1.00e+00	Ndufb9 Retreg2
Bone: trabecular thickness	8476.26	1	1	16.7	0	1.00e+00	Retreg2
Bone: trabecular tissue density	7288.68	2	2	33.3	0	1.00e+00	Ndufb9 Retreg2
Breakpoint value in progressive ratio session	18806.07	1	1	16.7	0	1.00e+00	Retreg2
Distance traveled before self-admin	12642.18	3	1	16.7	1	4.74e-04	Foxred1 Ndufb9 Retreg2
Distance traveled after self-admin	16241.13	2	1	16.7	0	1.00e+00	Foxred1 Retreg2
Delta time in closed arm before/after self-admin	93.76	3	1	16.7	0	1.00e+00	Foxred1 Ndufb9 Retreg2
Delta time in open arm before/after self-admin	5050.83	2	1	16.7	0	1.00e+00	Olfml2b Retreg2
Diff in mean of infusions in LGA sessions	9170.58	3	1	16.7	-1	2.01e-03	Ndufb9 Olfml2b Retreg2
Extinction: sum of active levers before priming	9483.4	3	3	50	0	1.00e+00	Foxred1 Ndufb9 Retreg2
Active lever presses in extinction session 6	376.86	2	1	16.7	0	1.00e+00	Foxred1 Retreg2
Delta distance traveled before/after self-admin	746.56	3	2	33.3	-0.99	6.80e-03	Foxred1 Ndufb9 Retreg2
Delta ambulatory time before/after self-admin	7723.98	3	1	16.7	-1	4.03e-04	Foxred1 Ndufb9 Retreg2
Time in closed arm before self-admin	13436.25	2	1	16.7	0	1.00e+00	Foxred1 Retreg2
Time in closed arm after self-admin	4591.18	1	1	16.7	0	1.00e+00	Retreg2
Time in open arm before self-admin	2940.91	2	2	33.3	0	1.00e+00	Ndufb9 Retreg2
Time in open arm after self-admin	176.73	3	2	33.3	0	1.00e+00	Foxred1 Ndufb9 Retreg2
Sum of active levers in priming session hrs 5-6	336.92	3	1	16.7	0	1.00e+00	Ndufb9 Olfml2b Retreg2
Time to tail flick, vehicle, before self-admin	4461.92	3	1	16.7	0	1.00e+00	Foxred1 Ndufb9 Retreg2
Time to tail flick, vehicle, after self-admin	8440.87	4	1	16.7	1	1.08e-04	Foxred1 Ndufb9 Retreg2 Supt7l
Time to tail flick, test, before self-admin	2732.6	3	2	33.3	0	1.00e+00	Foxred1 Ndufb9 Retreg2
Time to tail flick, test, after self-admin	496.1	3	2	33.3	0	1.00e+00	Foxred1 Ndufb9 Retreg2
Delta time to tail flick, vehicle, before/after SA	4909.69	1	1	16.7	0	1.00e+00	Retreg2
Delta time to tail flick, test, before/after SA	7848.65	2	1	16.7	0	1.00e+00	Ndufb9 Retreg2
Ambulatory time before self-admin	26306.16	2	2	33.3	0	1.00e+00	Foxred1 Retreg2
Ambulatory time after self-admin	26614.91	1	1	16.7	0	1.00e+00	Retreg2
Total heroin consumption	92.06	3	2	33.3	0	1.00e+00	Foxred1 Olfml2b Retreg2
Area under the delay curve	8272.54	2	1	16.7	0	1.00e+00	Olfml2b Retreg2
Delay disc. indifference point, 0s delay	1085.91	2	1	16.7	0	1.00e+00	Olfml2b Retreg2
Delay disc. indifference point, 16s delay	10984.31	2	1	16.7	0	1.00e+00	Olfml2b Retreg2
Delay disc. indifference point, 2s delay	155.27	1	1	16.7	0	1.00e+00	Retreg2
Delay disc. indifference point, 24s delay	16225.81	2	1	16.7	0	1.00e+00	Olfml2b Retreg2
Delay disc. indifference point, 4s delay	216.71	3	1	16.7	0	1.00e+00	Ndufb9 Olfml2b Retreg2
Delay disc. indifference point, 8s delay	16687.74	1	1	16.7	0	1.00e+00	Retreg2
Delay discount exponential model param	5648.94	2	1	16.7	0	1.00e+00	Olfml2b Retreg2
Delay discount hyperbolic model param	4101.49	2	1	16.7	0	1.00e+00	Olfml2b Retreg2
Fecal boli incidents, locomotor time 1	20408.55	2	1	16.7	0	1.00e+00	Olfml2b Retreg2
Change in fecal boli incidents, locomotor task	1903.71	3	2	33.3	0	1.00e+00	Adamts20 Ndufb9 Retreg2
Time >=10cm from walls, locomotor time 1	3258.29	3	1	16.7	-1	9.90e-04	Ndufb9 Olfml2b Retreg2
Bouts of movement, locomotor time 1	10785.17	1	1	16.7	0	1.00e+00	Retreg2
Total resting periods, locomotor time 1	2793.59	1	1	16.7	0	1.00e+00	Retreg2
Rest time, locomotor task time 1	11183.83	2	1	16.7	0	1.00e+00	Ndufb9 Retreg2
Distance moved, locomotor task time 1	22966.92	2	2	33.3	0	1.00e+00	Ndufb9 Retreg2
Vertical activity count, locomotor time 1	71190.42	1	1	16.7	0	1.00e+00	Retreg2
Time >=10cm from walls, locomotor time 2	23724.95	2	1	16.7	0	1.00e+00	Olfml2b Retreg2
Bouts of movement, locomotor time 2	20513.98	3	1	16.7	1	5.90e-05	Foxred1 Olfml2b Retreg2
Total resting periods, locomotor time 2	24767.8	3	1	16.7	1	8.44e-05	Foxred1 Olfml2b Retreg2
Rest time, locomotor task time 2	6381.61	3	1	16.7	-1	2.17e-03	Ndufb9 Olfml2b Retreg2
Distance moved, locomotor task time 2	8477.87	1	1	16.7	0	1.00e+00	Retreg2
Vertical activity count, locomotor time 2	53555.35	1	1	16.7	0	1.00e+00	Retreg2
Weight adjusted by age	23613.39	2	2	33.3	0	1.00e+00	Ndufb9 Retreg2
Seeking ratio, delayed vs. immediate footshock	13445.31	1	1	16.7	0	1.00e+00	Retreg2
Locomotion in novel chamber	1001	4	2	33.3	-0.98	1.85e-02	Ndufb9 Olfml2b Retreg2 Supt7l
Locomotion in novel chamber post-restriction	21812.77	2	1	16.7	0	1.00e+00	Ndufb9 Retreg2
Progressive ratio	22646.86	2	2	33.3	0	1.00e+00	Ndufb9 Retreg2
Food seeking constrained by brief footshock	941.83	2	1	16.7	0	1.00e+00	Ndufb9 Retreg2
Seeking ratio, punishment vs. effort	20653.58	2	2	33.3	0	1.00e+00	Ndufb9 Retreg2
Run reversals in cocaine runway, females	3145.88	3	1	16.7	0	1.00e+00	Foxred1 Olfml2b Retreg2
Run reversals in cocaine runway, males	2594.62	3	2	33.3	0	1.00e+00	Foxred1 Ndufb9 Retreg2
Latency to leave start box in cocaine runway	8151.76	2	1	16.7	0	1.00e+00	Olfml2b Retreg2
Latency to leave start box in cocaine runway, F	2400.79	3	2	33.3	0	1.00e+00	Ndufb9 Olfml2b Retreg2
Latency to leave start box in cocaine runway, M	581.54	3	1	16.7	0	1.00e+00	Foxred1 Ndufb9 Retreg2
Co content in liver	1133.25	1	1	16.7	0	1.00e+00	Retreg2
Cu content in liver	28.08	2	1	16.7	0	1.00e+00	Ndufb9 Retreg2
Fe content in liver	1344.53	1	1	16.7	0	1.00e+00	Retreg2
K content in liver	1519.62	1	1	16.7	0	1.00e+00	Retreg2
Mg content in liver	3022.31	2	1	16.7	0	1.00e+00	Olfml2b Retreg2
Mn content in liver	362.42	3	2	33.3	0	1.00e+00	Ndufb9 Olfml2b Retreg2
Na content in liver	1345.15	3	1	16.7	0	1.00e+00	Ndufb9 Olfml2b Retreg2
Rb content in liver	49.55	3	2	33.3	0	1.00e+00	Ndufb9 Olfml2b Retreg2
Se content in liver	8.14	2	0	0	0	1.00e+00	Ndufb9 Olfml2b
Zn content in liver	1887.46	2	2	33.3	0	1.00e+00	Ndufb9 Retreg2

Associations by panel

Tissue	RNA modality	# hits	% hits/tests	Avg chisq
Adipose	alternative polyA	0	0	1.04
Adipose	alternative TSS	0	0	1.03
Adipose	gene expression	0	0	1.05
Adipose	isoform ratio	0	0	1.05
Adipose	intron excision ratio	0	0	1.08
Adipose	mRNA stability	1	0	1.11
BLA	alternative polyA	0	0	1.06
BLA	alternative TSS	0	0	0.99
BLA	gene expression	0	0	1.04
BLA	isoform ratio	0	0	1.06
BLA	intron excision ratio	0	0	1.04
BLA	mRNA stability	0	0	1.07
Brain	alternative polyA	0	0	1.07
Brain	alternative TSS	0	0	1.04
Brain	gene expression	0	0	1.04
Brain	isoform ratio	0	0	1.06
Brain	intron excision ratio	0	0	1.04
Brain	mRNA stability	1	0	1.09
Eye	alternative polyA	0	0	1.07
Eye	alternative TSS	0	0	0.8
Eye	gene expression	0	0	1.03
Eye	isoform ratio	0	0	0.98
Eye	intron excision ratio	0	0	1.05
Eye	mRNA stability	0	0	1.14
IC	alternative polyA	0	0	1.14
IC	alternative TSS	0	0	1
IC	gene expression	0	0	1.05
IC	isoform ratio	0	0	1.09
IC	intron excision ratio	0	0	1.06
IC	mRNA stability	0	0	1.04
IL	alternative polyA	0	0	1.09
IL	alternative TSS	0	0	1.1
IL	gene expression	1	0	1.05
IL	isoform ratio	0	0	1.1
IL	intron excision ratio	0	0	1
IL	mRNA stability	0	0	1.07
LHb	alternative polyA	0	0	1.15
LHb	alternative TSS	0	0	1.08
LHb	gene expression	0	0	1.07
LHb	isoform ratio	0	0	1.1
LHb	intron excision ratio	0	0	0.99
LHb	mRNA stability	0	0	1.13
Liver	alternative polyA	0	0	1.08
Liver	alternative TSS	0	0	1.1
Liver	gene expression	0	0	1.05
Liver	isoform ratio	0	0	1.07
Liver	intron excision ratio	0	0	1.1
Liver	mRNA stability	0	0	1.07
NAcc	alternative polyA	2	0.1	72.96
NAcc	alternative TSS	0	0	1.08
NAcc	gene expression	0	0	1.05
NAcc	isoform ratio	0	0	1.05
NAcc	intron excision ratio	1	0	1.1
NAcc	mRNA stability	0	0	1.06
OFC	alternative polyA	0	0	1.03
OFC	alternative TSS	0	0	1.15
OFC	gene expression	0	0	1.03
OFC	isoform ratio	0	0	1.1
OFC	intron excision ratio	0	0	0.97
OFC	mRNA stability	0	0	1.01
PL	alternative polyA	0	0	1.14
PL	alternative TSS	0	0	1.01
PL	gene expression	1	0	1.05
PL	isoform ratio	0	0	1.06
PL	intron excision ratio	0	0	1.05
PL	mRNA stability	0	0	1.06
pVTA	alternative polyA	0	0	1.1
pVTA	alternative TSS	0	0	1.07
pVTA	gene expression	0	0	1.04
pVTA	isoform ratio	0	0	1.06
pVTA	intron excision ratio	0	0	1.07
pVTA	mRNA stability	0	0	1.09
RMTg	alternative polyA	0	0	1.08
RMTg	alternative TSS	0	0	1.03
RMTg	gene expression	0	0	1.09
RMTg	isoform ratio	0	0	1.21
RMTg	intron excision ratio	0	0	1.05
RMTg	mRNA stability	0	0	1.03