Hub : Genes

Faim2

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 NAcc gene expression Faim2 0.15 0.1 0.0e+00 0.18 0.19 0.19 0.2 2.6e-26 7.5e-28 9.4e-28 6.8e-29
2 Brain gene expression Faim2 0.47 0.14 0.0e+00 0.53 0.58 0.58 0.58 3.3e-58 5.4e-66 1.2e-65 9.6e-66
3 PL gene expression Faim2 0.06 0.04 4.9e-08 0.06 0.07 0.06 0.07 5.3e-07 2.6e-08 2.2e-07 9.8e-08
4 pVTA gene expression Faim2 0.55 0.15 0.0e+00 0.57 0.6 0.59 0.6 1.2e-55 4.2e-60 2.1e-58 2.3e-59
5 LHb mRNA stability Faim2 0.38 0.2 1.8e-07 0.21 0.23 0.19 0.22 1.3e-05 3.3e-06 2.7e-05 5.9e-06
6 RMTg gene expression Faim2 0.37 0.19 9.1e-07 0.21 0.2 0.21 0.22 2.9e-06 4.5e-06 2.4e-06 1.8e-06
7 LHb gene expression Faim2 0.57 0.19 3.1e-14 0.4 0.4 0.36 0.39 1.1e-10 1.7e-10 1.8e-09 3.7e-10
8 PL mRNA stability Faim2 0.16 0.12 1.3e-14 0.14 0.14 0.14 0.13 8.1e-15 4.9e-15 8.8e-15 2.3e-14
9 IL mRNA stability Faim2 0.26 0.16 4.1e-05 0.2 0.16 0.16 0.17 1.6e-05 1.0e-04 9.3e-05 5.5e-05
10 BLA gene expression Faim2 0.19 0.14 5.8e-08 0.14 0.12 0.11 0.12 4.7e-08 4.3e-07 2.3e-06 1.1e-06
11 IC gene expression Faim2 0.16 0.12 8.1e-06 0.12 0.11 0.11 0.11 7.0e-06 2.3e-05 3.4e-05 3.4e-05
12 Brain mRNA stability Faim2 0.28 0.12 0.0e+00 0.25 0.26 0.25 0.25 9.2e-23 4.4e-24 2.6e-23 1.4e-23
13 NAcc mRNA stability Faim2 0.13 0.08 2.2e-13 0.09 0.09 0.08 0.08 3.4e-13 2.6e-13 2.2e-12 1.2e-12

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13
Bone: apparent density9.716.718.3-4.0-4.1-3.9-4.1-4.1-4.3-4.2-4.1-4.2-4.0-4.0-4.0-4.0
Area under the delay curve0.70.91.4-1.2-1.0-1.0-1.0-0.9-0.7-1.1-0.9-0.9-0.8-0.8-0.8-0.8
BMI with tail6.823.327.5-5.2-5.0-5.0-5.0-4.9-4.8-4.9-4.7-4.8-4.6-4.6-4.6-4.5
BMI without tail1.54.65.9-2.4-2.3-2.3-2.3-2.2-2.1-2.2-2.1-2.1-2.0-2.0-2.0-2.0
Body weight6.729.235.6-6.0-5.6-5.7-5.6-5.4-5.3-5.5-5.3-5.4-5.1-5.1-5.1-5.0
Weight adjusted by age2.03.03.7-1.4-1.6-1.4-1.6-1.8-1.8-1.7-1.8-1.8-1.9-1.9-1.9-1.9
Bone surface11.521.022.7-4.6-4.6-4.5-4.6-4.6-4.8-4.6-4.6-4.5-4.5-4.5-4.5-4.5
Bone volume9.016.217.7-4.2-4.1-4.1-4.1-4.0-4.2-4.1-4.0-4.0-3.9-3.9-3.8-3.8
Breakpoint value in progressive ratio session1.51.82.2-1.3-1.3-1.2-1.3-1.4-1.4-0.8-1.4-1.3-1.5-1.5-1.5-1.5
Number of licking bursts0.50.91.81.41.11.21.10.90.70.90.80.70.80.80.70.7
Context. condit. distance diff. score0.20.30.4-0.4-0.5-0.5-0.5-0.5-0.4-0.6-0.5-0.6-0.6-0.6-0.5-0.5
Locomotion velocity, session 11.21.33.21.81.41.61.41.01.01.10.90.90.90.90.70.7
Locomotion distance, session 12.43.04.22.01.91.91.91.71.81.71.71.71.61.61.51.5
Locomotion velocity, session 20.20.20.30.60.50.60.50.50.40.50.50.60.50.50.40.4
Locomotion distance, session 22.23.14.12.01.92.01.91.71.71.71.71.81.61.61.51.6
Locomotion velocity, session 34.45.07.12.72.42.42.42.22.12.22.22.12.12.12.12.0
Locomotion distance, session 34.95.35.72.32.32.22.32.42.22.22.42.32.32.32.42.4
Stereotopy head waving bouts, day 30.81.01.9-0.6-0.8-0.6-0.8-1.0-1.4-1.0-1.1-1.1-1.0-1.0-1.2-1.2
Stereotopy head waving duration, day 30.50.61.0-0.3-0.6-0.4-0.5-0.8-1.0-0.8-0.9-0.8-0.8-0.8-1.0-1.0
Locomotion velocity, session 70.60.72.01.41.01.31.10.70.40.70.60.50.60.60.40.4
Locomotion distance, session 72.22.84.62.11.92.01.91.71.31.71.51.51.61.61.41.4
Stereotopy head waving bouts, day 71.11.21.6-1.0-1.1-1.1-1.1-1.1-1.3-1.2-1.1-1.2-1.1-1.1-1.0-1.1
Stereotopy head waving duration, day 71.11.31.5-1.2-1.2-1.2-1.2-1.1-1.1-1.2-1.1-1.2-1.1-1.1-1.0-1.0
Locomotion velocity, session 80.00.00.20.40.20.30.2-0.00.1-0.1-0.1-0.2-0.1-0.1-0.2-0.2
Locomotion distance, session 81.11.52.21.51.41.41.31.21.31.21.21.21.11.11.11.1
Degree of sensitization distance0.30.30.5-0.4-0.5-0.3-0.4-0.6-0.7-0.5-0.6-0.6-0.6-0.6-0.7-0.7
Degree of sensitization stereotypy0.10.10.4-0.6-0.4-0.6-0.5-0.3-0.3-0.4-0.3-0.4-0.2-0.2-0.1-0.1
Conditioned locomotion0.00.00.10.20.10.10.1-0.0-0.3-0.0-0.1-0.1-0.2-0.2-0.1-0.1
Cocaine response after cond. corrected0.00.00.00.00.10.10.10.10.10.00.10.00.10.10.10.1
Cocaine response after cond. not corrected0.50.60.80.70.70.70.80.80.90.70.80.70.90.90.80.8
Cocaine response before conditioning3.54.14.42.12.01.92.02.12.12.02.02.02.02.02.12.0
Saline control response0.00.00.10.1-0.10.0-0.1-0.2-0.1-0.2-0.2-0.2-0.2-0.2-0.3-0.3
Bone: connectivity density6.510.211.3-2.9-3.1-2.9-3.1-3.2-3.4-3.2-3.3-3.3-3.2-3.2-3.3-3.3
Bone: cortical apparent density0.10.20.20.40.40.40.40.40.40.40.40.30.40.40.40.4
Bone: cortical area10.215.717.2-3.8-3.9-3.8-3.9-4.0-4.1-3.9-4.0-3.9-4.0-4.0-4.0-4.0
Bone: cortical porosity0.40.40.70.30.50.30.40.60.80.60.70.70.70.70.80.8
Bone: cortical porosity0.60.71.00.50.70.50.60.80.90.80.90.90.90.91.01.0
Bone: cortical thickness3.55.86.5-2.2-2.3-2.2-2.3-2.4-2.5-2.4-2.5-2.4-2.4-2.4-2.5-2.5
Bone: cortical thickness0.00.00.10.10.00.20.1-0.1-0.3-0.1-0.1-0.2-0.1-0.1-0.3-0.2
Bone: cortical tissue density0.20.20.30.50.50.50.50.50.50.40.50.40.50.50.50.5
Condit. Reinf. active minus inactive responses0.00.10.10.30.30.30.20.20.20.30.20.30.20.20.20.1
Condit. Reinf. active-inactive response ratio0.30.40.4-0.5-0.5-0.5-0.6-0.6-0.7-0.6-0.6-0.6-0.6-0.6-0.6-0.7
Condit. Reinf. active responses0.60.81.11.00.91.00.90.90.81.00.91.00.80.80.80.8
Condit. Reinf. inactive responses3.13.84.22.02.02.02.02.02.01.92.02.01.91.91.91.9
Incentive salience index mean0.00.00.0-0.0-0.1-0.0-0.1-0.1-0.1-0.0-0.10.1-0.1-0.1-0.1-0.1
Condit. Reinf. lever presses0.10.10.4-0.6-0.5-0.5-0.5-0.3-0.3-0.3-0.3-0.2-0.3-0.3-0.2-0.2
Condit. Reinf. active minus inactive responses0.10.10.3-0.5-0.2-0.5-0.30.00.1-0.00.10.10.20.20.30.3
Condit. Reinf. active-inactive response ratio0.30.30.6-0.20.2-0.20.10.50.70.40.60.60.70.70.80.8
Condit. Reinf. active responses0.10.20.40.10.30.10.20.40.40.50.50.50.60.60.60.6
Condit. Reinf. inactive responses0.60.70.91.00.90.90.90.80.70.90.80.80.80.80.80.8
Condit. Reinf. lever presses0.00.00.0-0.0-0.1-0.1-0.1-0.1-0.2-0.1-0.1-0.1-0.0-0.0-0.1-0.1
Condit. Reinf. lever reinforcers received0.40.60.80.50.60.50.60.80.80.80.80.80.90.90.90.9
Conditioned reinforcement - actives1.22.02.81.11.31.21.31.41.51.31.51.31.71.71.51.5
Conditioned reinforcement - inactives4.77.07.62.82.72.72.72.62.72.32.62.72.72.72.52.5
Conditioned locomotion0.30.40.90.60.60.60.60.50.70.90.50.50.60.60.50.5
Patch foraging indifference point 0 sec2.85.29.73.12.62.82.62.22.02.32.02.22.02.01.81.7
Patch foraging indifference point AUC0.91.31.51.11.11.11.11.21.11.21.21.21.11.11.11.2
Delay disc. indifference point, 0s delay1.31.42.2-1.5-1.3-1.4-1.3-1.2-1.0-1.0-1.1-1.2-1.1-1.1-1.0-1.0
Delay disc. indifference point, 16s delay0.70.81.2-1.1-0.9-0.9-0.9-0.9-0.8-0.8-0.8-0.9-0.8-0.8-0.8-0.8
Delay disc. indifference point, 2s delay1.51.72.6-1.5-1.4-1.4-1.3-1.3-1.2-1.6-1.2-1.2-1.2-1.2-1.1-1.2
Delay disc. indifference point, 24s delay0.91.01.2-0.9-0.9-0.9-0.9-1.0-1.0-0.9-1.0-1.1-1.1-1.1-1.1-1.1
Delay disc. indifference point, 4s delay0.50.51.3-1.2-0.9-1.0-0.9-0.7-0.5-0.8-0.6-0.6-0.6-0.6-0.5-0.5
Delay disc. indifference point, 8s delay1.61.92.1-1.4-1.4-1.3-1.4-1.4-1.3-1.4-1.4-1.4-1.4-1.4-1.4-1.4
Indifference point function ln k3.35.87.9-2.8-2.6-2.6-2.5-2.4-2.3-2.4-2.3-2.4-2.3-2.3-2.2-2.2
Indifference point function log k3.35.87.9-2.8-2.6-2.6-2.5-2.4-2.3-2.4-2.3-2.4-2.3-2.3-2.2-2.2
Patch foraging total patch changes 0 sec2.75.09.13.02.52.82.52.12.02.32.02.12.02.01.71.7
Patch foraging total patch changes 12 sec3.64.68.02.82.42.62.42.12.02.21.92.21.81.81.71.7
Patch foraging total patch changes 18 sec4.36.69.03.02.83.02.82.62.42.72.42.42.32.32.22.2
Patch foraging total patch changes 24 sec2.34.05.82.42.22.32.22.01.82.11.82.01.81.81.71.6
Patch foraging total patch changes 6 sec3.65.510.43.22.72.92.72.32.02.42.12.12.12.11.81.8
Patch foraging time to switch 0 sec1.83.64.82.22.02.12.01.91.92.01.91.91.71.71.71.7
Patch foraging water rate 0 sec2.45.16.7-2.6-2.4-2.5-2.4-2.2-2.3-2.2-2.2-2.1-2.1-2.1-2.0-2.0
Patch foraging water rate 12 sec2.55.36.0-2.4-2.3-2.3-2.3-2.3-2.4-2.2-2.3-2.3-2.3-2.3-2.2-2.2
Patch foraging water rate 18 sec0.30.40.6-0.7-0.7-0.7-0.7-0.6-0.6-0.7-0.6-0.7-0.5-0.5-0.5-0.5
Patch foraging water rate 24 sec3.65.16.9-2.6-2.4-2.6-2.4-2.2-2.1-2.5-2.1-2.2-2.0-2.0-2.0-1.9
Patch foraging water rate 6 sec4.66.69.8-3.1-2.8-2.9-2.8-2.5-2.6-2.6-2.4-2.5-2.3-2.3-2.2-2.2
Seeking ratio, delayed vs. immediate footshock0.10.10.3-0.5-0.5-0.6-0.5-0.4-0.4-0.2-0.3-0.3-0.2-0.2-0.2-0.2
Distance traveled before self-admin0.91.22.11.41.31.41.31.00.81.30.90.91.01.00.80.7
Distance traveled after self-admin0.40.51.21.10.81.00.80.60.41.00.50.60.50.50.40.4
Extensor digitorum longus weight4.015.822.0-4.7-4.3-4.4-4.3-4.0-3.5-4.0-3.8-3.8-3.8-3.8-3.6-3.5
Bone: elastic displacement3.94.57.02.62.32.52.32.12.12.11.91.91.91.91.81.7
Bone: elastic work0.10.10.2-0.1-0.2-0.1-0.2-0.4-0.3-0.3-0.4-0.3-0.4-0.4-0.5-0.5
Bone: endosteal estimation8.418.319.7-4.4-4.4-4.3-4.4-4.3-4.3-4.2-4.3-4.0-4.3-4.3-4.2-4.2
Bone: endosteal perimeter7.115.017.7-4.2-4.0-4.0-4.0-3.9-3.9-3.8-3.8-3.7-3.8-3.8-3.7-3.7
Epididymis fat weight0.82.73.3-1.4-1.6-1.4-1.5-1.7-1.8-1.6-1.8-1.7-1.7-1.7-1.8-1.8
Delta time in closed arm before/after self-admin0.00.00.50.0-0.00.00.00.1-0.10.70.10.10.10.10.10.1
Delta time in open arm before/after self-admin1.11.01.41.21.11.11.11.01.10.61.01.11.01.01.01.0
Diff in mean of infusions in LGA sessions1.11.42.1-1.1-1.1-1.0-1.1-1.2-1.2-1.0-1.2-1.4-1.2-1.2-1.2-1.2
Delay discount exponential model param0.70.81.41.21.01.00.90.90.71.10.80.80.80.80.80.8
Extinction: sum of active levers before priming2.02.32.8-1.7-1.6-1.6-1.6-1.5-1.4-1.4-1.5-1.6-1.4-1.4-1.4-1.4
Active lever presses in extinction session 61.11.11.5-0.7-0.9-0.7-0.9-1.1-1.2-0.9-1.1-1.1-1.1-1.1-1.2-1.2
Bone: final force11.919.022.5-4.7-4.5-4.5-4.5-4.4-4.2-4.4-4.3-4.2-4.3-4.3-4.1-4.1
Bone: final moment13.121.025.2-5.0-4.8-4.8-4.8-4.6-4.4-4.6-4.5-4.3-4.5-4.5-4.3-4.3
Food consumed during 24 hour testing period1.52.12.4-1.4-1.5-1.4-1.5-1.4-1.5-1.5-1.5-1.5-1.4-1.4-1.4-1.4
Glucose0.10.10.30.40.10.30.1-0.3-0.3-0.2-0.4-0.4-0.4-0.4-0.5-0.5
Heart weight0.10.10.3-0.4-0.3-0.4-0.4-0.3-0.2-0.5-0.3-0.4-0.3-0.3-0.2-0.2
Delay discount hyperbolic model param0.70.81.41.21.01.00.90.90.71.10.80.80.80.80.80.8
Intermittent access intake day 1-15 change0.10.10.4-0.10.2-0.00.20.40.40.10.50.50.40.40.60.6
Intermittent access intake escalation0.00.10.2-0.5-0.2-0.4-0.20.10.1-0.10.20.30.10.10.30.4
Intermittent access intake escalation 20.20.20.50.10.30.10.30.50.50.40.60.70.60.60.70.7
Intermitt. access day 1 inactive lever presses0.20.60.90.60.70.50.70.81.00.50.80.90.80.80.90.9
Intermitt. access day 15 inactive lever presses0.61.32.10.50.80.50.81.21.31.11.31.41.31.31.41.4
Intermitt. access escalation Index0.40.61.0-0.4-0.6-0.5-0.6-0.8-0.9-1.0-0.9-0.8-0.8-0.8-0.9-0.9
Intermittent access day 1 total infusions1.01.62.21.51.41.41.41.31.30.91.21.31.21.21.21.2
Intermittent access day 15 total infusions1.01.52.01.11.21.11.21.31.31.01.31.41.21.21.31.4
Intermittent access terminal intake (last 3 days)1.62.02.71.31.41.31.41.51.51.21.51.61.41.41.51.6
Intermittent access total infusions2.32.83.31.61.71.61.61.71.71.31.71.81.61.61.71.8
Intermittent access day 1 locomotion0.20.20.70.80.70.80.60.40.40.40.30.40.30.30.20.2
Intermittent access day 15 total locomotion0.20.40.60.80.80.80.70.70.80.60.60.70.50.50.60.6
Intermittent access total locomotion1.72.12.81.71.61.61.61.41.51.41.41.41.31.31.31.3
Intermittent access standard deviation0.30.50.90.40.60.50.60.80.80.60.80.90.60.60.90.9
Left kidney weight0.83.96.1-2.5-2.2-2.4-2.2-1.9-2.0-1.9-1.8-1.8-1.8-1.8-1.6-1.6
Right kidney weight4.219.223.2-4.8-4.6-4.6-4.6-4.4-4.4-4.4-4.3-4.3-4.2-4.2-4.1-4.1
Cocaine induced anxiety2.63.74.0-2.0-2.0-1.9-2.0-2.0-1.9-2.0-1.9-1.9-1.8-1.8-1.9-1.9
Post-drug Anxiety3.33.54.5-2.1-2.0-2.1-2.0-1.9-1.9-1.9-1.9-1.8-1.6-1.6-1.8-1.8
Baseline Anxiety0.00.10.2-0.4-0.3-0.4-0.3-0.2-0.1-0.2-0.1-0.1-0.2-0.2-0.1-0.1
Tail length0.00.00.00.10.10.10.00.00.10.20.00.2-0.0-0.00.00.0
Length with tail1.56.77.7-2.8-2.7-2.7-2.7-2.6-2.5-2.6-2.5-2.5-2.6-2.6-2.4-2.4
Length without tail5.818.722.0-4.7-4.5-4.5-4.5-4.3-4.2-4.4-4.2-4.3-4.2-4.2-4.1-4.1
Times rat made contact with spout0.10.10.10.30.30.20.30.40.40.30.30.40.40.40.40.4
Lifetime Intake3.13.84.42.02.01.92.02.02.01.62.02.11.91.92.02.0
Liver weight, left9.816.219.5-4.4-4.2-4.2-4.2-4.0-4.1-4.1-3.9-3.8-4.0-4.0-3.7-3.7
Liver weight, right2.95.16.3-2.5-2.4-2.4-2.4-2.2-2.3-2.2-2.2-2.1-2.2-2.2-2.1-2.1
Locomotor activity1.62.53.11.81.61.61.61.61.51.51.61.41.61.61.51.5
Locomotor testing distance3.36.07.52.72.62.62.62.52.32.42.42.22.52.52.32.3
Locomotor testing rearing2.24.55.32.32.22.12.22.22.02.02.11.92.12.12.12.1
Locomotion in novel chamber1.82.34.7-2.2-1.8-2.0-1.8-1.4-1.4-1.5-1.3-1.4-1.2-1.2-1.1-1.0
Locomotion in novel chamber post-restriction0.00.00.1-0.3-0.1-0.2-0.10.10.20.10.20.10.20.20.30.3
Fecal boli incidents, locomotor time 11.52.22.71.21.51.41.51.51.61.31.51.21.61.61.61.6
Change in fecal boli incidents, locomotor task0.80.81.2-0.5-0.8-0.6-0.8-0.9-0.9-0.8-1.0-0.7-1.0-1.0-1.1-1.1
Time >=10cm from walls, locomotor time 10.10.10.10.30.10.30.2-0.1-0.2-0.1-0.2-0.3-0.2-0.2-0.3-0.3
Bouts of movement, locomotor time 10.00.00.10.0-0.00.0-0.0-0.10.00.3-0.0-0.1-0.1-0.1-0.1-0.1
Total resting periods, locomotor time 10.20.30.70.70.50.60.60.50.50.80.40.30.40.40.30.4
Rest time, locomotor task time 10.50.61.61.00.70.90.80.70.61.30.70.90.60.60.50.5
Distance moved, locomotor task time 10.00.00.10.0-0.1-0.1-0.1-0.2-0.3-0.1-0.2-0.1-0.3-0.3-0.2-0.2
Vertical activity count, locomotor time 10.61.42.2-1.1-1.1-1.2-1.2-1.2-1.2-1.5-1.2-1.2-1.1-1.1-1.1-1.1
Time >=10cm from walls, locomotor time 20.50.81.10.81.00.90.91.01.00.51.00.80.80.81.01.0
Bouts of movement, locomotor time 22.13.44.4-2.1-2.0-2.1-2.0-1.9-1.7-1.4-1.8-1.9-1.7-1.7-1.7-1.7
Total resting periods, locomotor time 22.13.74.7-2.2-2.1-2.2-2.1-2.0-1.9-1.5-1.9-1.9-1.8-1.8-1.8-1.8
Rest time, locomotor task time 20.10.10.30.50.20.30.20.1-0.10.60.00.40.00.0-0.0-0.1
Distance moved, locomotor task time 20.00.00.00.10.20.20.20.20.2-0.10.20.10.10.10.20.2
Vertical activity count, locomotor time 20.00.00.3-0.3-0.2-0.3-0.2-0.1-0.1-0.5-0.1-0.30.00.00.00.0
Light reinforcement 12.15.36.51.92.11.92.12.32.42.32.42.52.42.42.52.5
Light reinforcement 20.71.11.70.40.80.50.81.11.20.91.11.21.11.11.31.3
Bone: marrow area8.117.818.7-4.3-4.3-4.2-4.3-4.3-4.3-4.1-4.2-4.0-4.2-4.2-4.1-4.1
Bone: maximum diameter3.36.17.2-2.3-2.4-2.2-2.4-2.5-2.7-2.4-2.5-2.4-2.5-2.5-2.6-2.6
Bone: maximum force17.230.633.6-5.8-5.7-5.6-5.7-5.6-5.5-5.5-5.5-5.3-5.5-5.5-5.4-5.3
Bone: maximum moment18.732.936.8-6.1-5.9-5.9-5.9-5.8-5.7-5.7-5.7-5.4-5.7-5.7-5.5-5.5
Mean time between licks in bursts0.00.10.10.30.30.30.30.30.30.20.30.10.30.30.30.3
Mean num. licks in bursts0.10.10.5-0.7-0.5-0.6-0.5-0.3-0.1-0.3-0.2-0.1-0.2-0.2-0.1-0.1
Cd content in liver0.60.70.80.80.80.70.80.80.90.90.80.90.80.80.90.9
Co content in liver0.40.50.60.60.70.70.70.70.60.80.70.70.70.70.60.7
Cu content in liver1.01.21.7-0.5-0.9-0.7-0.9-1.1-1.1-1.0-1.2-1.2-1.2-1.2-1.3-1.3
Fe content in liver2.02.42.61.61.61.61.61.61.61.61.61.51.51.51.51.5
K content in liver0.00.00.10.10.10.30.2-0.00.20.1-0.0-0.1-0.1-0.1-0.2-0.1
Mg content in liver0.20.20.20.40.40.50.50.40.40.50.40.40.40.40.30.4
Mn content in liver0.00.00.00.00.00.10.0-0.1-0.1-0.0-0.1-0.1-0.1-0.1-0.2-0.2
Na content in liver0.00.00.2-0.10.10.10.10.10.40.10.20.10.10.10.20.2
Rb content in liver0.20.21.21.10.60.90.60.30.30.40.10.20.10.1-0.0-0.1
Se content in liver2.32.74.22.11.82.01.91.61.31.71.51.51.51.51.41.3
Sr content in liver1.31.11.4-0.9-1.0-0.9-1.0-1.1-1.2-1.1-1.1-1.1-1.1-1.1-1.1-1.1
Zn content in liver1.11.21.31.21.11.11.11.11.11.11.11.11.11.11.01.0
Bone: minimum diameter9.717.719.3-4.4-4.3-4.3-4.3-4.2-4.2-4.1-4.2-4.0-4.2-4.2-4.1-4.1
Time in familiar zone, hab. session 10.10.10.20.10.20.10.20.40.50.30.40.40.40.40.50.5
Time in novel zone, hab. session 10.20.20.3-0.2-0.3-0.2-0.3-0.4-0.5-0.4-0.4-0.5-0.4-0.4-0.5-0.5
Total zone transitions, hab. session 10.30.40.70.40.60.50.60.60.80.50.70.60.70.70.70.7
Total locomotion distance, hab. session 10.00.00.10.30.10.30.1-0.1-0.3-0.1-0.2-0.1-0.2-0.2-0.3-0.3
Locomotion velocity, hab. session 10.00.10.10.20.00.20.0-0.2-0.3-0.2-0.3-0.2-0.3-0.3-0.4-0.4
Time in familiar zone, hab. session 20.60.61.4-1.2-1.0-1.1-1.0-0.8-0.6-0.7-0.7-0.5-0.7-0.7-0.6-0.6
Time in novel zone, hab. session 20.50.51.41.20.91.10.90.60.50.60.50.30.50.50.40.3
Total zone transitions, hab. session 20.30.30.40.60.60.60.60.60.60.60.60.60.50.50.60.6
Total locomotion distance, hab. session 20.10.10.30.50.40.50.40.30.00.30.20.30.20.20.10.1
Locomotion velocity, hab. session 20.00.00.10.40.20.40.30.1-0.10.20.10.20.00.0-0.0-0.0
Novel to familiar place preference ratio1.81.92.1-1.3-1.4-1.3-1.4-1.4-1.4-1.4-1.4-1.4-1.4-1.4-1.4-1.4
Novelty place preference1.31.41.6-1.0-1.1-1.1-1.1-1.2-1.2-1.2-1.3-1.2-1.2-1.2-1.2-1.3
Time in novel zone, NPP test1.11.11.4-0.9-1.0-0.9-1.0-1.1-1.1-1.1-1.2-1.2-1.1-1.1-1.1-1.2
Total zone transitions, NPP test1.52.23.61.91.71.81.71.41.41.41.31.31.31.31.21.2
Total locomotion distance, NPP test1.82.54.52.11.82.01.81.51.31.51.41.51.41.41.31.2
Locomotion velocity, NPP test1.01.42.81.71.41.61.41.10.91.21.01.11.11.10.90.9
Intraocular pressure7.210.310.73.33.33.23.33.33.03.33.23.23.33.33.23.1
Delta distance traveled before/after self-admin0.00.00.00.0-0.1-0.1-0.1-0.00.00.10.00.1-0.1-0.10.00.0
Delta ambulatory time before/after self-admin0.10.10.20.30.20.20.20.30.30.50.30.40.20.20.30.3
Parametrial fat weight1.12.63.11.41.51.41.51.71.71.41.71.41.81.81.71.7
Pavlov. Cond. lever latency0.30.40.8-0.0-0.3-0.1-0.3-0.6-0.5-0.6-0.7-0.8-0.7-0.7-0.8-0.9
Pavlov. Cond. magazine entry latency0.10.10.5-0.7-0.3-0.5-0.30.00.20.10.20.30.20.20.30.4
Pavlov. Cond. change in total contacts0.10.10.7-0.8-0.4-0.6-0.4-0.00.0-0.00.10.20.10.10.30.3
Pavlov. Cond. index score0.10.10.4-0.7-0.3-0.5-0.30.10.00.10.20.30.20.20.30.4
Pavlov. Cond. latency score0.10.10.3-0.5-0.1-0.4-0.20.20.10.10.30.40.30.30.40.5
Pavlov. Cond. lever contacts0.70.81.40.20.60.30.60.90.90.91.01.11.01.01.11.2
Pavlov. Cond. magazine entry number0.00.10.20.40.20.30.2-0.1-0.1-0.1-0.2-0.3-0.2-0.2-0.3-0.3
Pavlov. Cond. intertrial magazine entries0.80.93.31.81.31.61.30.70.60.90.50.60.50.50.20.2
Pavlov. Cond. lever-magazine prob. diff.0.10.20.8-0.9-0.5-0.7-0.5-0.2-0.1-0.2-0.00.0-0.1-0.10.10.1
Pavlov. Cond. response bias0.20.20.5-0.20.2-0.00.10.40.50.50.50.70.50.50.60.7
Pavlov. Cond. lever latency0.20.30.9-1.0-0.7-0.8-0.7-0.5-0.3-0.5-0.4-0.3-0.5-0.5-0.3-0.3
Pavlov. Cond. magazine entry latency0.81.01.8-0.2-0.7-0.4-0.6-1.0-1.1-0.9-1.2-1.1-1.1-1.1-1.3-1.4
Pavlov. Cond. change in total contacts1.11.82.2-1.1-1.3-1.1-1.2-1.4-1.4-1.3-1.4-1.5-1.4-1.4-1.4-1.5
Pavlov. Cond. index score0.40.61.20.0-0.4-0.1-0.4-0.8-0.9-0.6-0.9-0.9-0.9-0.9-1.1-1.1
Pavlov. Cond. latency score0.40.51.00.1-0.3-0.0-0.3-0.7-0.8-0.5-0.8-0.8-0.8-0.8-1.0-1.0
Pavlov. Cond. lever contacts0.10.20.60.80.50.70.50.30.20.30.20.10.30.30.10.1
Pavlov. Cond. magazine entry number1.82.33.60.71.20.81.21.61.71.31.71.61.71.71.91.9
Pavlov. Cond. intertrial magazine entries5.58.29.42.62.72.52.72.92.92.83.03.03.03.03.13.1
Pavlov. Cond. lever-magazine prob. diff.0.60.81.6-0.1-0.6-0.3-0.6-0.9-1.1-0.8-1.1-1.0-1.0-1.0-1.2-1.3
Pavlov. Cond. response bias0.00.10.10.30.10.20.1-0.1-0.2-0.0-0.2-0.2-0.2-0.2-0.3-0.4
Time in closed arm before self-admin2.22.83.0-1.7-1.7-1.6-1.7-1.7-1.7-1.7-1.7-1.7-1.6-1.6-1.7-1.7
Time in closed arm after self-admin0.20.20.4-0.6-0.5-0.5-0.5-0.4-0.50.3-0.4-0.4-0.3-0.3-0.4-0.4
Time in open arm before self-admin0.10.10.30.50.40.50.30.20.00.30.10.00.10.10.10.1
Time in open arm after self-admin0.10.10.20.50.30.30.30.20.2-0.40.10.2-0.0-0.00.10.0
Bone: periosteal estimation12.726.728.4-5.2-5.2-5.1-5.3-5.2-5.3-5.1-5.2-5.0-5.1-5.1-5.1-5.1
Bone: periosteal perimeter10.918.820.3-4.5-4.4-4.4-4.4-4.4-4.4-4.3-4.3-4.2-4.3-4.3-4.2-4.2
Bone: post-yield work9.614.115.2-3.9-3.8-3.7-3.8-3.8-3.7-3.7-3.7-3.6-3.8-3.8-3.7-3.7
Progressive ratio test 1 active lever presses6.98.510.63.33.13.13.12.92.92.82.92.92.72.72.72.7
Progressive ratio test 1 breakpoint6.58.010.03.23.03.03.02.82.82.82.82.82.62.62.62.6
Progressive ratio test 1 inactive lever presses2.13.03.91.21.61.31.51.82.01.31.91.92.02.01.92.0
Progressive ratio test 2 active lever presses2.42.83.11.61.71.61.71.71.71.31.71.71.71.71.71.7
Progressive ratio test 2 breakpoint2.32.62.91.61.71.61.61.71.71.21.71.71.61.61.71.7
Progressive ratio test 2 inactive lever presses1.42.22.81.21.41.21.41.51.61.21.61.61.61.61.71.7
Incentive Sensitization - Responses0.10.20.6-0.7-0.4-0.6-0.5-0.3-0.3-0.8-0.2-0.3-0.2-0.2-0.1-0.1
Incentive Sensitization - Breakpoint0.10.10.4-0.6-0.3-0.5-0.4-0.2-0.2-0.7-0.1-0.2-0.1-0.10.00.0
Sum of active levers in priming session hrs 5-60.10.10.10.0-0.10.1-0.1-0.2-0.20.4-0.3-0.1-0.4-0.4-0.4-0.4
Progressive ratio0.40.71.51.21.01.21.00.80.40.70.70.70.70.70.50.5
Food seeking constrained by brief footshock1.21.42.61.61.41.61.51.21.10.81.11.01.11.10.90.9
Seeking ratio, punishment vs. effort0.00.00.1-0.2-0.1-0.2-0.1-0.00.2-0.10.0-0.0-0.0-0.00.10.1
Retroperitoneal fat weight0.41.73.01.71.51.61.51.31.11.41.21.21.21.21.01.0
Reaction time number correct1.22.43.0-1.7-1.5-1.5-1.5-1.6-1.6-1.5-1.5-1.5-1.5-1.5-1.6-1.5
Reaction time mean minus median4.711.612.63.43.43.33.33.43.33.63.43.53.53.53.33.3
Reaction time mean minus median AUC3.17.88.62.82.82.72.82.82.82.92.82.92.92.92.72.7
Reaction time num false alarms1.62.22.71.61.51.51.51.51.41.61.41.61.41.41.41.4
Reaction time num false alarms AUC2.03.13.61.81.81.71.71.81.71.91.71.91.71.71.71.7
Reaction time trials correct on left1.22.43.0-1.7-1.5-1.5-1.5-1.6-1.6-1.5-1.5-1.5-1.5-1.5-1.6-1.5
Reaction time trials on left1.01.92.4-1.6-1.4-1.3-1.3-1.4-1.4-1.4-1.4-1.4-1.3-1.3-1.4-1.4
Reaction time mean0.71.21.41.21.21.11.11.11.11.11.00.91.11.11.11.0
Reaction time mean AUC0.40.70.90.90.90.80.90.80.80.80.80.60.80.80.80.8
Median of all reaction times0.00.00.10.10.10.10.10.00.0-0.1-0.0-0.30.00.00.0-0.0
Reaction time omissions9.914.415.23.93.93.83.93.83.93.63.83.63.93.93.73.7
Reaction time false alarm rate2.73.74.32.11.91.81.91.91.92.01.92.11.91.91.91.9
Reaction time premature initiation rate6.38.79.72.72.82.72.83.03.03.13.03.03.13.13.03.0
Reaction time premature initiations2.23.94.71.61.81.71.92.02.02.12.12.02.22.22.02.1
Std. dev. reaction times5.19.310.13.23.13.03.13.13.03.13.03.03.13.13.02.9
Reaction time trials completed1.01.92.4-1.6-1.4-1.3-1.3-1.4-1.4-1.4-1.4-1.4-1.3-1.3-1.4-1.4
Reaction time trials AUC1.63.13.8-2.0-1.8-1.7-1.7-1.8-1.8-1.8-1.7-1.8-1.7-1.7-1.8-1.7
Run reversals in cocaine runway, females0.10.10.4-0.6-0.5-0.6-0.4-0.3-0.1-0.4-0.1-0.1-0.3-0.3-0.1-0.1
Run reversals in cocaine runway, males1.21.21.41.01.01.01.01.11.11.21.11.11.11.11.11.2
Latency to leave start box in cocaine runway0.00.00.00.10.20.10.20.20.20.20.2-0.00.20.20.20.2
Latency to leave start box in cocaine runway, F1.11.21.41.11.21.11.21.11.11.11.10.81.21.21.11.1
Latency to leave start box in cocaine runway, M1.81.72.0-1.4-1.4-1.4-1.4-1.3-1.3-1.2-1.3-1.3-1.3-1.3-1.2-1.2
Std. dev. time between licks in bursts1.21.62.11.41.31.31.31.31.01.21.21.11.31.31.21.2
Total sessions with >9 infusions3.23.94.32.02.01.92.02.02.01.72.02.12.02.02.02.0
Short access day 1 total inactive lever presses2.22.83.11.71.71.61.71.71.71.51.71.81.61.61.71.7
Short access day 10 total inactive lever presses0.00.10.3-0.00.0-0.10.00.20.30.50.20.40.30.30.30.3
Short access day 1 total infusions1.11.52.01.41.31.31.31.21.10.91.21.21.21.21.11.1
Short access day 10 total infusions2.22.93.41.81.81.71.71.71.71.61.71.81.51.51.71.7
Short access total infusions3.74.75.62.42.32.32.32.22.11.92.12.32.12.12.12.1
Short access day 1 locomotion0.30.40.50.70.70.70.70.60.70.50.60.60.70.70.60.6
Short access day 10 total locomotion0.20.30.50.60.60.60.60.60.70.50.60.60.50.50.50.5
Short access total locomotion1.11.41.61.21.21.21.21.21.31.11.11.21.11.11.11.1
One hour access (0.3 mA shock)0.30.30.7-0.10.30.00.20.50.60.20.70.60.60.60.80.8
Compulsive drug intake0.00.00.2-0.5-0.3-0.4-0.3-0.1-0.10.2-0.0-0.2-0.1-0.10.00.1
One hour access (shock baseline)0.10.10.2-0.20.0-0.10.00.20.3-0.20.30.30.40.40.40.4
Social response proportion0.30.30.60.80.50.50.50.50.50.50.50.70.60.60.50.5
Social responses8.210.611.73.43.23.13.23.33.23.33.33.43.33.33.23.2
Social time0.10.10.2-0.5-0.4-0.5-0.4-0.30.1-0.4-0.2-0.3-0.1-0.1-0.1-0.1
Soleus weight0.72.13.5-1.9-1.6-1.6-1.6-1.4-1.2-1.2-1.3-1.2-1.5-1.5-1.3-1.3
Bone: stiffness19.732.038.5-6.2-5.9-6.0-5.9-5.7-5.6-5.7-5.5-5.4-5.5-5.5-5.3-5.3
Tibialis anterior weight1.03.47.7-2.8-2.2-2.6-2.2-1.7-1.3-1.9-1.5-1.6-1.5-1.5-1.2-1.1
Time to tail flick, vehicle, before self-admin1.41.41.91.41.21.21.21.21.20.91.21.21.31.31.11.1
Time to tail flick, vehicle, after self-admin0.10.20.4-0.7-0.5-0.5-0.5-0.4-0.3-0.3-0.3-0.3-0.4-0.4-0.3-0.2
Time to tail flick, test, before self-admin0.10.10.20.50.40.40.40.30.50.10.30.40.20.20.30.3
Time to tail flick, test, after self-admin0.91.01.6-1.2-1.1-1.1-1.0-0.9-0.8-1.3-0.9-1.0-0.9-0.9-0.8-0.8
Delta time to tail flick, vehicle, before/after SA0.50.50.9-1.0-0.7-0.7-0.7-0.7-0.6-0.2-0.6-0.6-0.7-0.7-0.6-0.6
Delta time to tail flick, test, before/after SA0.20.30.6-0.8-0.6-0.7-0.6-0.5-0.5-0.5-0.4-0.5-0.2-0.2-0.3-0.4
Tibia length7.019.420.9-4.1-4.4-4.2-4.4-4.4-4.6-4.4-4.5-4.5-4.5-4.5-4.4-4.4
Ambulatory time before self-admin1.72.63.41.91.81.81.81.61.61.71.51.41.61.61.41.4
Ambulatory time after self-admin1.61.83.11.61.41.51.41.31.21.81.21.31.21.21.21.1
Bone: tissue strength1.71.71.9-1.3-1.3-1.4-1.4-1.3-1.1-1.4-1.3-1.3-1.4-1.4-1.2-1.2
Total heroin consumption1.01.11.5-1.0-1.0-0.9-1.0-1.1-1.1-0.7-1.1-1.1-1.2-1.2-1.1-1.1
Bone: trabecular number6.310.411.8-3.1-3.1-3.0-3.1-3.2-3.4-3.3-3.3-3.3-3.2-3.2-3.2-3.3
Bone: trabecular spacing2.63.54.01.61.81.61.81.92.02.01.91.91.91.91.91.9
Bone: trabecular thickness0.10.10.2-0.3-0.1-0.3-0.10.20.20.00.30.20.30.30.40.4
Bone: trabecular tissue density0.10.10.4-0.6-0.3-0.6-0.4-0.0-0.0-0.00.10.20.00.00.30.3
Water consumed over 24 hours0.10.10.2-0.0-0.3-0.2-0.2-0.3-0.4-0.3-0.4-0.3-0.4-0.4-0.4-0.4
Number of responses in last shaping day0.10.10.30.10.30.10.20.40.40.10.40.40.40.40.50.5