Hub : Genes

Faim2

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Brain gene expression Faim2 0.51 0.17 0.0e+00 0.52 0.56 0.57 0.57 2.8e-56 4.3e-63 9.2e-64 2.1e-63
2 pVTA gene expression Faim2 0.27 0.04 0.0e+00 0.53 0.56 0.54 0.49 1.6e-26 1.3e-28 1.6e-27 8.0e-24
3 pVTA alternative polyA NM_144756.2 0.1 0.08 2.3e-04 0.03 0.03 0.01 0.01 2.5e-02 1.5e-02 1.2e-01 7.2e-02
4 NAcc gene expression Faim2 0.2 0.14 0.0e+00 0.18 0.21 0.2 0.2 1.7e-20 4.0e-24 2.9e-23 4.1e-23
5 pVTA alternative polyA XM_017594665.2 0.19 0.2 1.3e-06 0.1 0.12 0.09 0.04 4.4e-05 1.0e-05 9.3e-05 5.1e-03
6 pVTA isoform ratio XM_017594665.2 0.22 0.2 3.9e-08 0.14 0.14 0.14 0.12 1.6e-06 7.7e-07 1.7e-06 9.1e-06
7 PL isoform ratio XM_017594665.2 0.04 0.03 1.7e-05 0.02 0.03 0.03 0.03 2.2e-03 1.5e-04 4.6e-04 3.0e-04
8 PL gene expression Faim2 0.06 0.04 7.4e-09 0.07 0.08 0.07 0.07 4.3e-08 4.9e-09 3.2e-08 3.2e-08
9 LHb mRNA stability Faim2 0.12 0.09 5.3e-03 0.06 0.09 0.07 0.07 1.8e-02 4.7e-03 9.9e-03 8.1e-03
10 LHb gene expression Faim2 0.59 0.17 4.4e-16 0.4 0.44 0.44 0.44 1.6e-10 6.6e-12 7.3e-12 7.6e-12
11 BLA gene expression Faim2 0.15 0.1 7.3e-09 0.13 0.15 0.14 0.06 1.2e-07 1.6e-08 6.3e-08 2.7e-04
12 RMTg gene expression Faim2 0.29 0.17 2.5e-06 0.13 0.18 0.15 0.17 2.7e-04 1.6e-05 7.3e-05 2.2e-05
13 Brain isoform ratio NM_144756.2 0.08 0.06 2.5e-07 0.07 0.08 0.06 0.07 1.6e-07 1.0e-07 1.5e-06 4.1e-07
14 NAcc mRNA stability Faim2 0.35 0 1.6e-09 0.06 0.06 0.06 0.06 6.5e-08 1.1e-07 1.6e-07 2.4e-07
15 PL isoform ratio NM_144756.2 0.02 0.02 6.7e-03 0.01 0.01 0.01 0 4.4e-02 6.7e-02 6.2e-02 1.2e-01
16 NAcc isoform ratio XM_017594665.2 0.03 0.03 2.8e-03 0.01 0.01 0.01 0.01 2.7e-02 2.9e-02 2.3e-02 6.2e-02
17 BLA isoform ratio XM_017594665.2 0.06 0.06 3.6e-03 0.03 0.02 0.01 0.02 1.0e-02 2.5e-02 8.6e-02 3.7e-02
18 PL alternative polyA XM_017594665.2 0.06 0.04 1.7e-09 0.09 0.08 0.08 0.08 1.3e-09 3.6e-09 4.0e-09 4.9e-09
19 PL mRNA stability Faim2 0.09 0.07 1.4e-09 0.09 0.09 0.07 0.09 5.8e-10 7.2e-10 1.5e-08 5.2e-10
20 Brain alternative polyA XM_017594665.2 0.15 0.1 8.4e-12 0.12 0.12 0.12 0.12 1.3e-11 1.5e-11 6.1e-11 2.7e-11
21 Brain isoform ratio XM_017594665.2 0.15 0.11 8.5e-11 0.12 0.11 0.11 0.12 3.7e-11 1.4e-10 1.9e-10 8.9e-11
22 Brain mRNA stability Faim2 0.27 0.12 0.0e+00 0.27 0.27 0.27 0.28 7.3e-25 2.9e-25 1.5e-25 1.2e-25
23 BLA alternative polyA XM_017594665.2 0.09 0.08 2.3e-04 0.05 0.03 0.03 0 8.1e-04 9.0e-03 9.1e-03 1.8e-01
24 OFC alternative TSS NM_144756.2 0.13 0.1 2.4e-03 0.05 0.05 0.04 0.11 2.6e-02 3.0e-02 3.6e-02 1.8e-03
25 OFC alternative TSS NM_144756.2 0.12 0.09 4.0e-03 0.04 0.04 0.06 0.09 3.9e-02 3.7e-02 1.6e-02 3.6e-03
26 PL alternative polyA NM_144756.2 0.05 0.02 3.4e-06 0.05 0.04 0.04 0.04 5.5e-06 2.4e-05 1.0e-05 1.3e-05
27 pVTA isoform ratio NM_144756.2 0.11 0.09 2.2e-04 0.03 0.03 0.02 0.01 1.6e-02 2.1e-02 6.0e-02 7.0e-02

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27
Bone: apparent density9.916.519.04.2-4.1-4.1-4.14.24.24.1-4.1-4.2-4.2-4.2-4.2-4.24.14.4-4.2-4.2-4.2-4.2-4.2-4.2-4.1-3.63.63.63.43.4
Area under the delay curve1.01.11.61.0-1.1-1.1-1.11.11.11.1-1.1-1.0-1.0-1.0-1.0-1.01.10.8-0.9-0.9-0.9-0.9-0.9-0.9-0.9-1.31.11.21.01.1
BMI with tail4.414.315.84.0-3.9-3.9-3.93.93.93.9-3.9-3.9-3.9-3.9-3.8-3.83.73.6-3.7-3.6-3.6-3.6-3.6-3.6-3.6-3.53.83.83.73.7
BMI without tail0.10.10.5-0.1-0.1-0.1-0.10.10.10.1-0.20.00.00.00.10.2-0.2-0.30.30.30.30.30.30.30.4-0.70.60.60.70.7
Body weight5.824.326.85.2-5.1-5.0-5.05.15.15.1-5.0-5.1-5.1-5.1-5.1-5.05.04.9-5.0-4.9-4.9-4.9-4.9-4.9-4.8-4.94.64.64.34.4
Weight adjusted by age1.31.52.21.3-1.1-1.1-1.11.21.21.1-1.0-1.3-1.3-1.2-1.3-1.41.51.4-1.4-1.5-1.5-1.5-1.5-1.5-1.4-1.20.50.50.40.3
Bone surface12.021.123.04.7-4.7-4.7-4.74.74.74.7-4.6-4.7-4.7-4.7-4.7-4.74.54.8-4.6-4.6-4.6-4.6-4.6-4.6-4.6-4.24.34.34.14.1
Bone volume9.516.217.54.1-4.2-4.2-4.24.24.24.2-4.2-4.1-4.1-4.1-4.1-4.03.84.1-3.9-3.9-3.9-3.9-3.9-3.9-3.9-3.94.04.03.93.9
Breakpoint value in progressive ratio session0.20.20.40.5-0.4-0.4-0.40.50.50.4-0.4-0.5-0.5-0.5-0.5-0.50.50.5-0.6-0.5-0.5-0.5-0.6-0.6-0.6-0.50.30.30.00.3
Number of licking bursts0.91.12.9-0.91.11.11.1-1.1-1.1-1.11.21.01.01.01.00.9-0.9-0.80.90.90.90.90.90.90.81.7-1.2-1.2-1.2-1.2
Context. condit. distance diff. score0.20.20.30.4-0.5-0.5-0.50.50.50.5-0.5-0.5-0.5-0.5-0.5-0.50.50.5-0.6-0.5-0.5-0.5-0.5-0.5-0.4-0.30.40.40.40.4
Locomotion velocity, session 12.02.14.4-1.41.61.61.6-1.5-1.5-1.51.71.41.41.41.31.1-1.0-1.11.00.90.90.91.01.01.01.8-2.1-2.0-2.1-2.1
Locomotion distance, session 12.73.43.9-1.91.91.92.0-1.9-1.9-1.92.01.91.91.91.91.8-1.7-1.91.71.71.71.71.71.71.71.9-2.0-1.9-1.9-1.9
Locomotion velocity, session 20.20.30.3-0.60.50.60.5-0.5-0.5-0.50.60.50.50.50.50.5-0.5-0.40.50.50.50.50.50.50.50.5-0.6-0.6-0.6-0.6
Locomotion distance, session 22.53.64.3-2.02.02.02.0-2.0-2.0-2.02.01.91.91.91.91.8-1.7-1.71.71.71.71.71.71.71.72.0-2.1-2.0-2.1-2.0
Locomotion velocity, session 34.55.36.0-2.32.42.42.4-2.4-2.4-2.42.42.42.42.42.32.2-2.1-2.12.22.12.12.12.22.22.32.4-2.3-2.3-2.3-2.2
Locomotion distance, session 34.75.26.0-2.42.32.32.3-2.3-2.3-2.32.22.42.42.42.42.4-2.4-2.22.52.42.42.42.42.42.41.7-1.9-1.9-1.8-1.8
Stereotopy head waving bouts, day 30.60.71.81.0-0.7-0.7-0.70.70.70.7-0.6-0.8-0.8-0.8-0.9-1.01.01.3-1.1-1.0-1.0-1.0-1.0-1.0-1.0-0.20.20.30.10.2
Stereotopy head waving duration, day 30.30.40.80.7-0.4-0.4-0.40.50.50.4-0.3-0.6-0.6-0.6-0.6-0.70.80.9-0.9-0.7-0.7-0.7-0.8-0.8-0.80.1-0.1-0.0-0.2-0.1
Locomotion velocity, session 71.11.23.3-1.01.21.21.2-1.1-1.1-1.21.31.01.01.00.90.7-0.6-0.40.60.70.70.70.60.60.61.5-1.7-1.7-1.8-1.8
Locomotion distance, session 72.83.65.4-1.92.02.02.0-2.0-2.0-2.02.11.91.91.91.81.7-1.6-1.41.61.61.61.61.61.61.72.0-2.3-2.3-2.3-2.3
Stereotopy head waving bouts, day 70.70.81.20.9-0.9-0.9-0.90.90.90.9-0.9-0.9-0.9-0.9-0.9-0.90.91.1-0.9-0.9-0.9-0.9-0.8-0.8-0.9-0.70.90.90.90.9
Stereotopy head waving duration, day 71.21.41.61.2-1.2-1.2-1.21.21.21.2-1.2-1.2-1.2-1.2-1.2-1.21.21.2-1.1-1.2-1.2-1.2-1.1-1.1-1.2-1.01.31.31.21.2
Locomotion velocity, session 80.10.10.9-0.20.20.20.3-0.2-0.2-0.20.30.10.10.10.1-0.00.2-0.0-0.1-0.2-0.2-0.2-0.1-0.1-0.10.9-0.6-0.6-0.7-0.7
Locomotion distance, session 81.21.72.3-1.51.41.41.4-1.4-1.4-1.41.41.31.31.31.31.2-1.1-1.31.21.21.21.21.21.21.31.5-1.4-1.4-1.3-1.3
Degree of sensitization distance0.30.30.50.5-0.4-0.4-0.40.40.40.4-0.3-0.5-0.5-0.5-0.6-0.60.70.7-0.7-0.7-0.7-0.7-0.7-0.7-0.6-0.10.10.1-0.0-0.0
Degree of sensitization stereotypy0.30.30.90.5-0.6-0.6-0.60.60.60.6-0.7-0.5-0.5-0.5-0.4-0.40.30.3-0.3-0.4-0.4-0.4-0.3-0.3-0.4-0.70.90.91.00.9
Conditioned locomotion0.00.00.30.2-0.1-0.1-0.10.10.10.1-0.0-0.1-0.1-0.1-0.1-0.20.20.3-0.1-0.2-0.2-0.2-0.2-0.2-0.20.5-0.1-0.1-0.1-0.1
Cocaine response after cond. corrected0.00.00.10.00.00.0-0.0-0.0-0.0-0.0-0.00.00.00.00.00.0-0.0-0.00.00.00.00.00.00.00.1-0.2-0.0-0.0-0.1-0.0
Cocaine response after cond. not corrected0.40.40.6-0.60.60.60.6-0.7-0.7-0.70.60.70.70.70.70.7-0.7-0.70.70.70.70.70.70.70.80.3-0.5-0.5-0.5-0.5
Cocaine response before conditioning3.13.74.1-2.02.01.91.9-2.0-2.0-2.01.92.02.02.02.02.0-2.0-2.02.02.02.02.02.02.02.01.8-1.6-1.6-1.5-1.5
Saline control response0.10.10.30.3-0.2-0.2-0.20.30.30.2-0.2-0.3-0.3-0.3-0.3-0.40.40.5-0.4-0.4-0.4-0.4-0.5-0.5-0.40.4-0.1-0.1-0.1-0.1
Bone: connectivity density6.610.413.03.4-3.2-3.2-3.23.33.33.2-3.1-3.4-3.3-3.3-3.4-3.43.43.6-3.4-3.4-3.4-3.4-3.4-3.4-3.5-2.52.62.62.42.4
Bone: cortical apparent density0.20.30.5-0.50.60.60.6-0.6-0.6-0.60.50.60.60.60.60.6-0.7-0.50.60.60.60.60.60.60.60.4-0.5-0.5-0.4-0.5
Bone: cortical area8.212.414.33.7-3.6-3.6-3.63.63.63.6-3.5-3.7-3.7-3.7-3.7-3.73.73.8-3.7-3.6-3.6-3.6-3.7-3.7-3.6-3.13.03.12.82.8
Bone: cortical porosity0.30.30.6-0.50.40.40.4-0.4-0.4-0.40.30.50.50.50.60.7-0.7-0.80.70.70.70.70.70.70.70.00.10.10.20.2
Bone: cortical porosity0.60.61.0-0.80.70.60.6-0.7-0.7-0.70.50.80.80.80.90.9-1.0-1.01.01.01.01.01.01.01.00.2-0.2-0.2-0.1-0.1
Bone: cortical thickness2.54.15.22.2-2.0-2.0-2.02.12.12.1-2.0-2.1-2.1-2.1-2.1-2.22.22.3-2.2-2.2-2.2-2.2-2.2-2.2-2.1-1.51.61.61.51.5
Bone: cortical thickness0.10.10.5-0.00.10.10.1-0.1-0.1-0.10.20.00.00.0-0.0-0.10.20.3-0.2-0.1-0.1-0.1-0.2-0.2-0.10.5-0.6-0.6-0.6-0.7
Bone: cortical tissue density0.30.40.6-0.60.70.70.7-0.7-0.7-0.70.70.70.70.70.70.7-0.8-0.60.70.70.70.70.70.70.60.4-0.6-0.6-0.5-0.6
Condit. Reinf. active minus inactive responses0.10.10.2-0.30.30.30.3-0.3-0.3-0.30.30.30.30.30.30.2-0.2-0.20.20.40.40.40.20.20.20.2-0.4-0.4-0.3-0.4
Condit. Reinf. active-inactive response ratio0.20.20.40.6-0.5-0.5-0.50.50.50.5-0.4-0.5-0.5-0.5-0.5-0.60.60.6-0.5-0.4-0.4-0.4-0.6-0.6-0.6-0.40.30.30.30.2
Condit. Reinf. active responses0.70.91.0-0.91.01.01.0-1.0-1.0-1.01.00.90.90.90.90.9-0.8-0.80.91.01.01.00.80.80.80.9-1.0-1.0-1.0-1.0
Condit. Reinf. inactive responses2.93.54.0-2.01.91.91.9-1.9-1.9-1.91.91.91.91.91.91.9-1.8-1.91.91.81.81.81.81.81.91.8-1.8-1.8-1.8-1.7
Incentive salience index mean0.00.00.00.1-0.1-0.1-0.00.10.10.1-0.0-0.1-0.1-0.1-0.1-0.10.10.1-0.10.00.00.0-0.1-0.1-0.1-0.1-0.0-0.0-0.0-0.1
Condit. Reinf. lever presses0.20.20.80.4-0.5-0.5-0.50.50.50.5-0.6-0.4-0.5-0.5-0.4-0.30.30.3-0.2-0.3-0.3-0.3-0.3-0.3-0.3-0.90.70.70.80.7
Condit. Reinf. active minus inactive responses0.20.21.40.2-0.4-0.4-0.40.40.40.4-0.6-0.2-0.2-0.3-0.1-0.0-0.1-0.10.10.10.10.10.20.20.1-0.31.11.01.21.2
Condit. Reinf. active-inactive response ratio0.30.31.1-0.2-0.1-0.1-0.1-0.0-0.00.1-0.30.20.10.10.30.4-0.6-0.60.60.50.50.50.60.60.5-0.10.90.91.11.1
Condit. Reinf. active responses0.10.10.3-0.30.10.10.1-0.2-0.2-0.20.00.30.30.30.30.4-0.5-0.40.50.50.50.50.60.60.50.10.30.30.40.4
Condit. Reinf. inactive responses0.70.91.1-0.91.01.01.0-1.0-1.0-1.01.00.90.90.90.90.9-0.8-0.80.80.90.90.90.90.90.90.7-1.0-1.0-1.0-1.0
Condit. Reinf. lever presses0.00.00.10.0-0.0-0.0-0.00.00.00.0-0.0-0.0-0.0-0.0-0.0-0.00.00.10.0-0.0-0.0-0.00.00.0-0.00.30.00.0-0.00.0
Condit. Reinf. lever reinforcers received0.30.40.8-0.70.60.50.5-0.6-0.6-0.60.50.70.70.70.70.8-0.8-0.80.80.80.80.80.90.90.80.6-0.2-0.2-0.1-0.1
Conditioned reinforcement - actives1.61.62.1-1.41.31.31.3-1.3-1.3-1.31.31.31.31.31.31.4-1.3-1.51.41.41.41.41.41.41.41.0-0.9-0.9-1.0-0.8
Conditioned reinforcement - inactives2.42.73.1-1.81.71.71.7-1.7-1.7-1.71.71.71.71.71.71.7-1.7-1.71.61.61.61.61.61.61.71.5-1.4-1.4-1.3-1.2
Conditioned locomotion0.30.40.8-0.80.60.60.6-0.6-0.6-0.60.60.70.70.70.70.7-0.7-0.90.70.70.70.70.70.70.80.6-0.3-0.3-0.4-0.2
Patch foraging indifference point 0 sec3.96.310.8-2.42.72.72.7-2.6-2.6-2.62.82.42.42.52.32.1-2.1-1.91.92.02.02.01.91.91.93.0-3.3-3.2-3.1-3.3
Patch foraging indifference point AUC0.30.41.0-0.50.60.60.6-0.6-0.6-0.60.50.60.60.60.60.7-0.8-0.50.80.70.70.70.60.60.51.0-0.4-0.4-0.3-0.4
Delay disc. indifference point, 0s delay1.61.72.61.3-1.4-1.4-1.41.41.41.4-1.4-1.3-1.3-1.3-1.3-1.21.41.0-1.1-1.1-1.1-1.1-1.1-1.1-1.0-1.31.61.61.61.6
Delay disc. indifference point, 16s delay0.90.91.31.0-1.0-1.0-1.01.01.01.0-1.0-1.0-1.0-1.0-1.0-0.91.00.8-0.9-0.9-0.9-0.9-0.9-0.9-0.9-1.11.11.10.91.1
Delay disc. indifference point, 2s delay1.71.92.71.4-1.5-1.5-1.51.51.41.5-1.5-1.4-1.4-1.4-1.4-1.31.41.3-1.3-1.3-1.3-1.3-1.3-1.3-1.3-1.71.31.31.41.2
Delay disc. indifference point, 24s delay1.11.01.41.2-1.0-1.0-1.01.01.01.0-1.0-1.1-1.1-1.1-1.1-1.11.21.1-1.1-1.1-1.1-1.1-1.1-1.1-1.1-1.00.70.70.70.6
Delay disc. indifference point, 4s delay0.60.71.80.7-0.8-0.8-0.90.80.80.8-0.9-0.7-0.7-0.7-0.7-0.60.70.4-0.5-0.5-0.5-0.5-0.5-0.5-0.5-1.11.31.31.11.3
Delay disc. indifference point, 8s delay2.12.22.61.5-1.5-1.5-1.51.51.51.5-1.4-1.5-1.5-1.5-1.5-1.51.61.5-1.5-1.5-1.5-1.5-1.5-1.5-1.5-1.51.21.31.01.2
Indifference point function ln k4.76.68.12.6-2.7-2.7-2.72.72.72.7-2.7-2.6-2.6-2.6-2.6-2.52.62.3-2.4-2.5-2.5-2.5-2.4-2.4-2.3-2.82.62.62.62.5
Indifference point function log k4.76.68.12.6-2.7-2.7-2.72.72.72.7-2.7-2.6-2.6-2.6-2.6-2.52.62.3-2.4-2.5-2.5-2.5-2.4-2.4-2.3-2.82.62.62.62.5
Patch foraging total patch changes 0 sec3.75.910.1-2.42.62.62.6-2.5-2.5-2.62.72.42.42.42.32.1-2.0-1.91.92.02.02.01.91.91.92.9-3.1-3.1-3.0-3.2
Patch foraging total patch changes 12 sec3.95.17.8-2.22.42.42.4-2.4-2.3-2.42.52.22.22.22.12.0-2.1-1.81.91.91.91.91.81.81.62.8-2.8-2.8-2.8-2.8
Patch foraging total patch changes 18 sec6.07.611.3-2.82.92.92.9-2.9-2.9-2.93.02.82.82.82.72.6-2.6-2.32.52.62.62.62.32.32.33.4-3.1-3.1-3.0-3.0
Patch foraging total patch changes 24 sec3.44.16.6-2.02.22.22.2-2.1-2.1-2.12.22.02.02.02.01.8-1.9-1.61.91.71.71.71.71.71.62.6-2.4-2.3-2.3-2.3
Patch foraging total patch changes 6 sec4.56.610.4-2.52.82.82.8-2.7-2.7-2.72.92.52.52.62.42.3-2.2-1.92.22.12.12.12.12.12.03.1-3.2-3.2-3.2-3.2
Patch foraging time to switch 0 sec2.33.64.3-1.92.02.02.0-2.0-2.0-2.02.01.91.91.91.91.9-1.9-1.81.92.12.12.11.71.71.81.4-1.8-1.8-1.9-1.7
Patch foraging water rate 0 sec2.94.65.22.2-2.3-2.3-2.32.22.22.2-2.3-2.2-2.2-2.2-2.2-2.12.02.1-2.1-2.1-2.1-2.1-1.9-1.9-2.0-1.92.22.22.22.1
Patch foraging water rate 12 sec3.45.26.62.4-2.3-2.3-2.32.42.42.4-2.3-2.4-2.4-2.4-2.4-2.42.62.5-2.5-2.3-2.3-2.3-2.3-2.3-2.3-1.72.02.01.81.8
Patch foraging water rate 18 sec0.30.40.60.6-0.7-0.7-0.70.70.70.7-0.7-0.6-0.6-0.7-0.6-0.60.60.5-0.8-0.6-0.6-0.6-0.6-0.6-0.5-0.80.60.60.70.6
Patch foraging water rate 24 sec3.95.56.62.4-2.5-2.5-2.52.52.42.5-2.5-2.4-2.4-2.4-2.3-2.22.32.1-2.3-2.1-2.1-2.1-2.1-2.1-2.0-2.32.62.62.42.5
Patch foraging water rate 6 sec4.46.47.62.6-2.7-2.7-2.72.72.72.7-2.8-2.6-2.6-2.6-2.5-2.42.42.4-2.4-2.3-2.3-2.3-2.2-2.2-2.2-2.62.72.72.72.7
Seeking ratio, delayed vs. immediate footshock0.40.40.70.6-0.7-0.7-0.70.70.70.7-0.8-0.6-0.7-0.7-0.6-0.60.50.6-0.5-0.6-0.6-0.6-0.4-0.4-0.5-0.40.80.80.90.8
Distance traveled before self-admin1.61.72.8-1.31.41.41.4-1.4-1.4-1.41.51.31.31.31.31.2-1.0-1.01.11.01.01.01.21.21.11.2-1.6-1.6-1.7-1.6
Distance traveled after self-admin0.30.30.7-0.50.60.60.6-0.6-0.6-0.60.70.60.60.60.50.5-0.6-0.30.40.40.40.40.50.50.40.6-0.8-0.8-0.8-0.8
Extensor digitorum longus weight4.316.919.84.2-4.3-4.3-4.34.34.34.3-4.4-4.2-4.2-4.2-4.1-3.93.73.7-3.8-3.8-3.8-3.8-3.8-3.8-3.7-4.44.54.44.34.4
Bone: elastic displacement4.95.57.7-2.32.52.52.5-2.4-2.4-2.42.52.32.32.32.32.1-2.0-2.22.02.02.02.02.02.02.12.6-2.8-2.8-2.7-2.8
Bone: elastic work0.00.10.20.3-0.2-0.2-0.20.20.20.2-0.1-0.2-0.2-0.2-0.2-0.30.30.2-0.3-0.3-0.3-0.3-0.3-0.3-0.3-0.4-0.0-0.0-0.1-0.1
Bone: endosteal estimation8.117.719.04.3-4.4-4.4-4.44.44.44.4-4.3-4.4-4.4-4.4-4.3-4.34.24.2-4.2-4.1-4.1-4.1-4.2-4.2-4.2-4.04.04.03.93.8
Bone: endosteal perimeter6.914.315.73.9-4.0-4.0-4.03.93.93.9-4.0-3.9-3.9-3.9-3.8-3.83.73.7-3.7-3.6-3.6-3.6-3.7-3.7-3.7-3.53.83.83.73.6
Epididymis fat weight0.10.20.50.5-0.4-0.4-0.40.50.50.4-0.4-0.5-0.5-0.5-0.5-0.60.70.6-0.6-0.6-0.6-0.6-0.6-0.6-0.5-0.00.20.30.10.2
Delta time in closed arm before/after self-admin0.20.20.40.5-0.4-0.4-0.40.50.50.5-0.4-0.5-0.5-0.5-0.5-0.50.60.7-0.4-0.4-0.4-0.4-0.5-0.5-0.6-0.20.20.20.30.2
Delta time in open arm before/after self-admin4.34.14.7-2.22.12.12.1-2.1-2.1-2.12.02.12.12.12.12.1-2.1-2.12.02.02.02.02.02.02.12.1-1.9-1.8-1.8-1.8
Diff in mean of infusions in LGA sessions1.71.92.71.4-1.4-1.4-1.41.41.41.4-1.3-1.4-1.4-1.4-1.4-1.41.61.4-1.4-1.4-1.4-1.4-1.4-1.4-1.4-1.61.21.21.11.1
Delay discount exponential model param0.91.01.7-1.01.01.01.0-1.0-1.0-1.01.11.01.01.01.00.9-1.0-0.80.90.90.90.90.90.90.81.3-1.1-1.1-0.9-1.1
Extinction: sum of active levers before priming0.70.70.90.9-0.8-0.8-0.80.80.80.8-0.8-0.8-0.8-0.8-0.8-0.81.00.7-0.8-0.8-0.8-0.8-0.7-0.7-0.8-0.90.90.90.80.9
Active lever presses in extinction session 60.30.30.60.7-0.5-0.5-0.50.50.50.5-0.5-0.6-0.6-0.6-0.6-0.60.60.8-0.7-0.6-0.6-0.6-0.7-0.7-0.7-0.40.30.40.10.3
Bone: final force11.117.919.44.4-4.4-4.4-4.44.44.44.4-4.4-4.3-4.4-4.4-4.3-4.24.14.1-4.1-4.1-4.1-4.1-4.1-4.1-4.1-4.24.14.14.04.0
Bone: final moment12.219.821.74.6-4.6-4.6-4.74.64.64.6-4.7-4.6-4.6-4.6-4.5-4.44.34.3-4.3-4.3-4.3-4.3-4.3-4.3-4.2-4.44.44.44.34.3
Food consumed during 24 hour testing period1.62.02.31.5-1.5-1.5-1.51.51.51.5-1.4-1.5-1.5-1.4-1.5-1.41.41.5-1.4-1.4-1.4-1.4-1.4-1.4-1.4-1.21.31.31.31.2
Glucose0.10.11.1-0.10.30.30.3-0.2-0.2-0.20.40.10.10.10.0-0.10.20.2-0.1-0.1-0.1-0.1-0.2-0.2-0.21.1-0.6-0.6-0.6-0.6
Heart weight0.10.10.30.3-0.3-0.3-0.30.30.30.3-0.3-0.3-0.3-0.3-0.3-0.30.30.2-0.3-0.3-0.3-0.3-0.3-0.3-0.3-0.20.50.50.30.5
Delay discount hyperbolic model param1.01.01.7-1.01.11.11.1-1.1-1.1-1.11.11.01.01.01.01.0-1.0-0.80.90.90.90.90.90.90.91.3-1.2-1.2-1.0-1.1
Intermittent access intake day 1-15 change1.21.22.0-1.11.01.01.0-1.0-1.0-1.00.81.11.11.11.21.3-1.4-1.31.41.41.41.41.41.41.30.7-0.3-0.3-0.3-0.1
Intermittent access intake escalation0.80.81.5-0.80.70.70.7-0.8-0.8-0.70.50.90.90.91.01.1-1.2-1.11.21.21.21.21.21.21.10.30.10.10.10.2
Intermittent access intake escalation 21.31.32.3-1.11.01.01.0-1.1-1.1-1.00.81.21.21.21.21.4-1.5-1.41.51.51.51.51.51.51.40.6-0.3-0.3-0.2-0.2
Intermitt. access day 1 inactive lever presses1.41.42.6-1.31.11.11.1-1.2-1.2-1.11.01.31.31.21.31.4-1.5-1.61.41.31.31.31.41.41.60.8-0.6-0.6-0.4-0.5
Intermitt. access day 15 inactive lever presses0.80.81.6-1.00.80.80.8-0.8-0.8-0.80.70.90.90.91.01.1-1.2-1.21.11.11.11.11.11.11.20.4-0.3-0.4-0.1-0.2
Intermitt. access escalation Index0.40.40.9-0.50.60.60.7-0.6-0.6-0.60.70.50.60.60.50.4-0.4-0.30.40.40.40.40.40.40.30.7-0.9-0.9-0.9-0.9
Intermittent access day 1 total infusions1.31.51.9-1.41.31.31.3-1.3-1.3-1.31.31.31.31.31.31.2-1.2-1.31.21.21.21.21.21.21.21.0-1.1-1.1-1.2-1.1
Intermittent access day 15 total infusions2.83.24.0-1.91.81.81.8-1.8-1.8-1.81.71.91.91.91.91.9-2.0-1.92.02.02.02.02.02.01.91.4-1.2-1.2-1.3-1.1
Intermittent access terminal intake (last 3 days)3.03.34.3-1.91.81.81.8-1.8-1.9-1.81.71.91.91.91.92.0-2.1-1.92.02.12.12.12.02.01.91.4-1.2-1.2-1.3-1.1
Intermittent access total infusions2.83.14.0-1.91.81.81.8-1.8-1.8-1.81.71.81.81.81.91.9-1.9-1.91.92.02.02.01.91.91.91.3-1.2-1.2-1.3-1.0
Intermittent access day 1 locomotion1.01.11.5-1.21.11.11.1-1.1-1.1-1.11.21.11.11.11.01.0-0.8-1.00.90.90.90.90.90.91.01.0-1.2-1.2-1.2-1.1
Intermittent access day 15 total locomotion1.71.92.5-1.51.41.41.4-1.4-1.4-1.41.41.41.41.41.41.4-1.4-1.61.41.41.41.41.41.41.51.3-1.1-1.0-1.0-0.9
Intermittent access total locomotion3.94.45.1-2.32.22.22.2-2.2-2.2-2.22.22.22.22.22.12.1-2.0-2.22.01.91.91.92.02.02.12.1-2.1-2.1-2.0-1.9
Intermittent access standard deviation0.30.40.8-0.60.40.40.4-0.5-0.5-0.50.30.60.60.60.60.8-0.9-0.80.80.80.80.80.80.80.80.10.10.10.10.2
Left kidney weight0.61.74.61.2-1.3-1.3-1.31.31.31.3-1.4-1.2-1.2-1.2-1.1-1.01.01.0-1.0-0.9-0.9-0.9-1.0-1.0-0.9-2.11.71.81.61.8
Right kidney weight2.57.010.22.8-2.7-2.7-2.72.72.72.7-2.6-2.7-2.7-2.7-2.7-2.62.62.6-2.6-2.6-2.6-2.6-2.6-2.6-2.6-3.22.52.62.32.4
Cocaine induced anxiety1.01.22.11.0-1.1-1.1-1.11.11.11.1-1.1-1.1-1.1-1.1-1.1-1.11.11.1-1.1-1.0-1.0-1.0-1.1-1.1-1.1-1.41.21.20.91.1
Post-drug Anxiety5.46.07.22.5-2.5-2.5-2.52.52.52.5-2.5-2.5-2.5-2.5-2.5-2.42.32.4-2.4-2.3-2.3-2.3-2.4-2.4-2.4-2.72.52.52.32.4
Baseline Anxiety0.90.91.21.1-1.0-1.0-1.01.01.01.0-1.0-1.0-1.0-1.0-1.0-1.00.91.0-1.0-0.9-0.9-0.9-1.0-1.0-1.0-0.90.70.60.90.6
Tail length0.10.30.6-0.60.50.50.5-0.5-0.5-0.50.50.60.60.60.60.6-0.6-0.60.70.60.60.60.70.70.7-0.3-0.3-0.3-0.2-0.3
Length with tail1.96.99.02.7-2.7-2.7-2.72.72.72.7-2.6-2.7-2.7-2.7-2.7-2.72.72.7-2.6-2.7-2.7-2.7-2.6-2.6-2.6-3.02.42.32.32.2
Length without tail7.015.317.34.2-4.0-3.9-3.94.04.04.0-3.8-4.1-4.0-4.0-4.1-4.14.14.1-4.1-4.1-4.1-4.1-4.1-4.1-4.1-3.43.33.33.03.1
Times rat made contact with spout0.10.10.2-0.30.30.30.3-0.3-0.3-0.30.20.30.30.30.30.4-0.5-0.40.40.40.40.40.40.40.40.3-0.2-0.2-0.1-0.1
Lifetime Intake3.13.54.1-2.01.91.91.9-1.9-1.9-1.91.92.02.02.02.02.0-2.0-1.92.02.02.02.02.02.01.91.5-1.5-1.5-1.6-1.4
Liver weight, left1.83.03.21.8-1.8-1.8-1.71.81.81.8-1.7-1.8-1.8-1.8-1.8-1.81.71.7-1.8-1.8-1.8-1.8-1.8-1.8-1.7-1.61.61.51.51.5
Liver weight, right1.52.53.21.6-1.6-1.6-1.61.61.61.6-1.6-1.6-1.6-1.6-1.6-1.61.51.6-1.6-1.6-1.6-1.6-1.6-1.6-1.5-1.81.41.41.41.4
Locomotor activity1.42.22.6-1.61.51.61.5-1.5-1.5-1.61.51.51.51.51.51.5-1.3-1.51.41.41.41.41.61.61.60.6-1.5-1.5-1.4-1.4
Locomotor testing distance3.45.76.4-2.52.52.52.5-2.5-2.5-2.52.52.52.52.52.52.4-2.1-2.32.32.32.32.32.42.42.51.8-2.4-2.4-2.3-2.3
Locomotor testing rearing2.64.04.7-2.22.12.12.1-2.1-2.1-2.12.12.12.12.12.02.0-1.7-1.92.02.02.02.02.02.02.11.6-2.0-2.0-1.8-1.9
Locomotion in novel chamber1.21.54.01.1-1.3-1.3-1.31.21.21.3-1.5-1.1-1.1-1.1-1.0-0.90.80.8-0.7-0.7-0.7-0.7-0.7-0.7-0.7-1.41.91.91.92.0
Locomotion in novel chamber post-restriction0.10.10.60.3-0.4-0.4-0.50.40.40.4-0.5-0.3-0.3-0.3-0.3-0.20.20.1-0.2-0.0-0.0-0.0-0.1-0.1-0.2-0.60.40.40.80.4
Fecal boli incidents, locomotor time 11.92.12.7-1.51.51.51.5-1.5-1.5-1.51.41.51.51.51.61.6-1.5-1.61.61.61.61.61.61.61.61.2-1.0-0.9-1.2-0.8
Change in fecal boli incidents, locomotor task1.21.11.91.2-1.0-1.0-1.01.11.11.0-0.9-1.1-1.1-1.1-1.2-1.21.11.2-1.4-1.2-1.2-1.2-1.3-1.3-1.3-0.80.50.50.40.4
Time >=10cm from walls, locomotor time 10.10.10.50.20.10.10.1-0.0-0.0-0.00.2-0.1-0.1-0.1-0.2-0.30.50.4-0.4-0.4-0.4-0.4-0.4-0.4-0.40.4-0.5-0.4-0.7-0.5
Bouts of movement, locomotor time 10.00.00.00.2-0.1-0.1-0.10.10.10.1-0.1-0.1-0.1-0.1-0.1-0.10.20.1-0.1-0.1-0.1-0.1-0.2-0.2-0.2-0.00.00.1-0.10.1
Total resting periods, locomotor time 10.20.20.7-0.40.50.50.5-0.5-0.5-0.50.60.50.50.50.40.4-0.3-0.40.30.40.40.40.30.30.30.7-0.7-0.7-0.8-0.7
Rest time, locomotor task time 10.50.61.3-0.70.80.80.8-0.8-0.8-0.80.80.70.70.70.70.7-0.9-0.60.50.70.70.70.50.50.60.9-0.9-0.8-1.1-0.8
Distance moved, locomotor task time 10.00.00.10.2-0.1-0.1-0.10.10.10.1-0.1-0.1-0.1-0.2-0.2-0.20.20.3-0.1-0.3-0.3-0.3-0.2-0.2-0.20.10.10.10.20.1
Vertical activity count, locomotor time 11.21.31.61.1-1.1-1.1-1.11.11.11.1-1.1-1.1-1.1-1.2-1.1-1.11.31.1-1.0-1.2-1.2-1.2-1.1-1.1-1.1-1.21.21.31.11.2
Time >=10cm from walls, locomotor time 20.60.61.0-1.00.80.80.8-0.8-0.8-0.80.80.90.80.90.90.9-0.8-1.00.90.90.90.90.90.91.00.5-0.3-0.2-0.5-0.1
Bouts of movement, locomotor time 22.93.13.61.8-1.9-1.9-1.91.91.91.9-1.9-1.8-1.8-1.8-1.8-1.71.81.6-1.7-1.7-1.7-1.7-1.6-1.6-1.6-1.81.81.71.81.7
Total resting periods, locomotor time 23.33.64.12.0-2.0-2.0-2.02.02.02.0-2.0-1.9-1.9-1.9-1.9-1.81.81.7-1.8-1.8-1.8-1.8-1.7-1.7-1.8-1.81.91.92.01.8
Rest time, locomotor task time 20.10.10.40.10.10.10.1-0.1-0.1-0.10.20.00.00.00.0-0.0-0.20.2-0.2-0.0-0.0-0.0-0.1-0.1-0.20.4-0.6-0.6-0.5-0.6
Distance moved, locomotor task time 20.00.00.1-0.40.20.20.2-0.2-0.2-0.20.20.20.20.20.20.2-0.2-0.20.20.10.10.10.20.20.30.1-0.0-0.0-0.10.0
Vertical activity count, locomotor time 20.10.10.4-0.0-0.1-0.1-0.10.10.10.1-0.2-0.1-0.1-0.1-0.1-0.00.0-0.00.1-0.0-0.0-0.00.00.00.1-0.40.60.60.50.7
Light reinforcement 12.34.25.7-2.22.02.02.0-2.0-2.0-2.01.82.12.12.12.22.3-2.4-2.32.42.32.32.32.42.42.31.6-1.2-1.3-1.1-1.1
Light reinforcement 20.50.71.6-1.00.60.60.6-0.7-0.7-0.60.50.80.80.80.91.0-1.1-1.31.21.01.01.01.11.11.2-0.40.10.10.20.2
Bone: marrow area7.917.118.34.2-4.3-4.3-4.34.34.34.3-4.2-4.3-4.3-4.3-4.2-4.24.14.2-4.1-4.1-4.1-4.1-4.1-4.1-4.2-3.93.93.93.73.7
Bone: maximum diameter2.74.96.22.3-2.2-2.2-2.22.22.22.2-2.1-2.3-2.3-2.3-2.3-2.42.42.5-2.4-2.4-2.4-2.4-2.4-2.4-2.4-1.81.71.81.61.6
Bone: maximum force15.827.229.15.4-5.4-5.4-5.45.45.45.4-5.4-5.4-5.4-5.4-5.3-5.35.25.1-5.1-5.2-5.2-5.2-5.1-5.1-5.1-5.14.94.94.74.7
Bone: maximum moment17.129.431.75.6-5.6-5.6-5.65.65.65.6-5.6-5.6-5.6-5.6-5.5-5.45.35.3-5.3-5.4-5.4-5.4-5.3-5.3-5.3-5.45.35.25.05.0
Mean time between licks in bursts0.00.00.1-0.20.10.10.1-0.1-0.1-0.10.10.10.10.10.10.2-0.1-0.10.10.10.10.10.10.10.3-0.2-0.1-0.1-0.2-0.1
Mean num. licks in bursts0.20.31.30.4-0.6-0.6-0.60.50.50.5-0.6-0.5-0.5-0.5-0.4-0.30.20.1-0.3-0.3-0.3-0.3-0.3-0.3-0.2-1.10.80.70.80.8
Cd content in liver0.80.81.0-1.00.90.90.9-0.9-0.9-0.90.90.90.90.91.01.0-0.9-0.91.01.01.01.01.01.01.00.9-0.7-0.7-0.7-0.7
Co content in liver0.81.01.2-1.01.01.01.0-1.0-1.0-1.01.01.01.01.01.11.1-1.0-1.11.01.11.11.11.11.11.10.5-0.8-0.8-0.7-0.7
Cu content in liver0.50.61.20.9-0.7-0.7-0.70.80.80.8-0.7-0.8-0.8-0.8-0.8-0.91.10.7-0.9-0.9-0.9-0.9-0.9-0.9-0.9-0.30.30.30.30.2
Fe content in liver0.60.71.2-0.90.90.90.9-0.9-0.9-0.91.00.90.90.90.80.8-0.6-0.80.70.70.70.70.70.70.80.8-1.1-1.1-1.1-1.1
K content in liver0.10.10.20.3-0.1-0.1-0.10.10.10.1-0.0-0.2-0.2-0.2-0.3-0.30.30.3-0.4-0.4-0.4-0.4-0.4-0.4-0.40.1-0.3-0.3-0.4-0.4
Mg content in liver0.10.10.4-0.20.40.40.4-0.4-0.4-0.40.40.30.30.30.30.3-0.3-0.10.20.20.20.20.20.20.20.5-0.6-0.6-0.6-0.6
Mn content in liver0.10.10.20.4-0.4-0.4-0.40.40.40.4-0.4-0.4-0.4-0.4-0.4-0.40.30.4-0.4-0.4-0.4-0.4-0.4-0.4-0.2-0.40.20.20.30.1
Na content in liver0.10.10.3-0.30.40.40.4-0.4-0.4-0.40.40.30.30.30.30.3-0.3-0.30.20.20.20.20.20.20.20.5-0.5-0.5-0.6-0.5
Rb content in liver1.21.53.3-1.11.31.31.3-1.2-1.2-1.21.41.11.11.11.00.9-0.8-0.80.80.80.80.80.80.80.91.7-1.8-1.8-1.8-1.8
Se content in liver1.31.63.2-1.21.31.41.4-1.3-1.3-1.31.41.21.21.21.21.1-1.0-0.91.01.01.01.01.01.01.01.8-1.6-1.6-1.5-1.6
Sr content in liver0.10.10.20.3-0.2-0.2-0.20.20.20.2-0.2-0.3-0.3-0.2-0.3-0.30.30.5-0.3-0.3-0.3-0.3-0.3-0.3-0.30.10.20.20.10.2
Zn content in liver2.73.03.5-1.81.81.81.8-1.8-1.8-1.81.81.81.81.81.71.7-1.6-1.61.61.61.61.61.61.61.61.7-1.8-1.8-1.9-1.8
Bone: minimum diameter9.217.118.54.3-4.3-4.3-4.34.34.34.3-4.3-4.3-4.3-4.3-4.2-4.24.14.1-4.1-4.0-4.0-4.0-4.1-4.1-4.0-4.04.03.93.83.8
Time in familiar zone, hab. session 10.10.10.3-0.40.20.20.2-0.2-0.3-0.20.10.30.30.30.30.4-0.5-0.50.40.50.50.50.40.40.50.10.10.10.20.2
Time in novel zone, hab. session 10.20.10.30.4-0.3-0.3-0.30.30.30.3-0.3-0.4-0.4-0.4-0.4-0.50.50.5-0.5-0.5-0.5-0.5-0.5-0.5-0.5-0.10.10.10.00.1
Total zone transitions, hab. session 10.20.30.5-0.70.50.50.5-0.5-0.5-0.50.50.60.60.60.60.6-0.6-0.70.60.50.50.50.60.60.70.5-0.3-0.3-0.2-0.2
Total locomotion distance, hab. session 10.10.10.5-0.00.20.30.3-0.2-0.2-0.20.40.10.10.10.0-0.10.20.2-0.1-0.1-0.1-0.1-0.1-0.1-0.10.6-0.7-0.7-0.7-0.7
Locomotion velocity, hab. session 10.10.10.30.10.10.10.1-0.1-0.1-0.10.2-0.0-0.00.0-0.1-0.20.30.3-0.2-0.2-0.2-0.2-0.2-0.2-0.20.5-0.5-0.5-0.6-0.6
Time in familiar zone, hab. session 20.80.91.80.8-1.0-1.0-1.01.01.01.0-1.1-0.9-0.9-0.9-0.8-0.70.70.6-0.6-0.7-0.7-0.7-0.7-0.7-0.6-1.11.31.31.31.3
Time in novel zone, hab. session 20.80.82.0-0.70.91.01.0-0.9-0.9-0.91.10.80.80.80.70.6-0.5-0.50.50.50.50.50.50.50.51.3-1.4-1.3-1.4-1.4
Total zone transitions, hab. session 20.30.40.5-0.70.60.60.6-0.6-0.6-0.60.60.60.60.60.60.6-0.6-0.60.60.50.50.50.60.60.70.7-0.6-0.6-0.6-0.6
Total locomotion distance, hab. session 20.20.30.7-0.40.50.50.5-0.5-0.5-0.50.60.40.40.40.40.3-0.3-0.10.30.40.40.40.30.30.30.8-0.8-0.8-0.8-0.8
Locomotion velocity, hab. session 20.10.10.4-0.20.30.40.3-0.3-0.3-0.30.40.30.30.30.20.2-0.10.10.20.30.30.30.10.10.20.6-0.6-0.6-0.6-0.7
Novel to familiar place preference ratio1.81.82.31.5-1.4-1.4-1.41.41.41.4-1.3-1.4-1.4-1.4-1.4-1.41.31.3-1.4-1.5-1.5-1.5-1.4-1.4-1.4-1.11.21.21.11.1
Novelty place preference1.21.31.71.3-1.1-1.1-1.11.11.11.1-1.1-1.2-1.2-1.1-1.2-1.21.21.1-1.2-1.3-1.3-1.3-1.2-1.2-1.2-0.70.90.90.80.8
Time in novel zone, NPP test1.01.01.51.2-1.0-1.0-1.01.01.01.0-0.9-1.0-1.0-1.0-1.0-1.11.11.0-1.1-1.2-1.2-1.2-1.1-1.1-1.1-0.50.80.80.70.7
Total zone transitions, NPP test1.92.64.0-1.71.71.71.8-1.7-1.7-1.71.81.61.61.61.61.4-1.3-1.41.31.31.31.31.31.31.41.8-2.0-2.0-2.0-2.0
Total locomotion distance, NPP test2.43.35.3-1.71.91.91.9-1.9-1.9-1.92.01.81.81.81.71.6-1.5-1.31.51.51.51.51.51.51.42.2-2.3-2.3-2.3-2.3
Locomotion velocity, NPP test1.42.03.6-1.31.51.51.5-1.5-1.5-1.51.61.41.41.41.31.2-1.1-1.01.11.21.21.21.11.11.11.8-1.9-1.9-1.9-1.9
Intraocular pressure7.210.111.5-3.43.23.23.2-3.2-3.2-3.23.13.33.33.33.33.3-3.3-3.23.33.33.33.33.43.43.32.6-2.7-2.8-2.5-2.6
Delta distance traveled before/after self-admin0.10.10.20.3-0.3-0.4-0.40.30.30.4-0.4-0.3-0.3-0.3-0.3-0.30.10.3-0.4-0.2-0.2-0.2-0.3-0.3-0.2-0.10.40.40.50.4
Delta ambulatory time before/after self-admin0.00.00.10.1-0.1-0.1-0.10.10.10.1-0.2-0.1-0.1-0.1-0.0-0.0-0.20.0-0.00.10.10.1-0.0-0.0-0.00.00.30.20.30.3
Parametrial fat weight2.04.05.3-2.02.02.02.0-2.0-2.0-2.01.92.12.12.02.12.1-2.3-2.12.12.22.22.22.12.11.92.0-1.6-1.6-1.5-1.5
Pavlov. Cond. lever latency0.20.20.60.3-0.2-0.2-0.20.20.20.2-0.0-0.4-0.3-0.3-0.4-0.50.60.4-0.7-0.8-0.8-0.8-0.7-0.7-0.60.4-0.3-0.3-0.4-0.4
Pavlov. Cond. magazine entry latency0.20.31.20.3-0.5-0.5-0.50.50.50.5-0.7-0.3-0.4-0.4-0.3-0.20.10.0-0.00.00.00.0-0.0-0.0-0.1-1.11.01.01.11.1
Pavlov. Cond. change in total contacts0.30.31.50.3-0.5-0.5-0.50.40.40.5-0.7-0.3-0.3-0.3-0.2-0.0-0.10.00.10.20.20.20.10.10.1-1.21.11.11.21.2
Pavlov. Cond. index score0.20.20.90.2-0.3-0.3-0.40.30.30.3-0.5-0.2-0.2-0.2-0.10.1-0.10.00.20.30.30.30.20.20.1-0.90.90.80.90.9
Pavlov. Cond. latency score0.10.20.70.1-0.2-0.2-0.20.20.10.2-0.3-0.0-0.0-0.10.00.2-0.2-0.00.30.40.40.40.30.30.2-0.70.70.70.80.8
Pavlov. Cond. lever contacts0.50.51.2-0.70.50.50.5-0.6-0.6-0.50.30.70.70.70.80.9-0.9-0.91.01.11.11.11.01.01.0-0.20.10.10.30.2
Pavlov. Cond. magazine entry number0.10.10.50.00.10.10.1-0.1-0.1-0.10.2-0.0-0.00.0-0.1-0.20.20.2-0.3-0.3-0.3-0.3-0.2-0.2-0.20.7-0.6-0.5-0.6-0.6
Pavlov. Cond. intertrial magazine entries1.61.96.4-1.11.41.51.5-1.3-1.3-1.41.71.11.11.11.00.7-0.5-0.60.50.60.60.60.50.50.52.2-2.4-2.4-2.5-2.5
Pavlov. Cond. lever-magazine prob. diff.0.30.41.30.5-0.6-0.6-0.60.60.60.6-0.7-0.5-0.5-0.5-0.4-0.30.20.3-0.2-0.1-0.1-0.1-0.2-0.2-0.2-1.11.11.01.11.1
Pavlov. Cond. response bias0.10.10.4-0.10.0-0.0-0.0-0.1-0.1-0.0-0.10.10.10.10.20.3-0.4-0.30.40.50.50.50.40.40.3-0.60.50.40.60.5
Pavlov. Cond. lever latency0.30.42.00.5-0.6-0.6-0.60.60.60.6-0.7-0.5-0.5-0.5-0.4-0.30.10.1-0.2-0.2-0.2-0.2-0.2-0.2-0.1-1.41.01.01.11.1
Pavlov. Cond. magazine entry latency0.60.71.50.8-0.6-0.6-0.50.60.70.6-0.4-0.8-0.8-0.8-0.9-1.01.11.1-1.2-1.2-1.2-1.2-1.2-1.2-1.20.3-0.1-0.1-0.3-0.2
Pavlov. Cond. change in total contacts0.91.21.71.1-1.1-1.1-1.11.11.11.1-1.0-1.2-1.2-1.1-1.2-1.21.31.3-1.2-1.3-1.3-1.3-1.2-1.2-1.3-0.30.80.80.70.7
Pavlov. Cond. index score0.30.31.10.4-0.1-0.1-0.10.20.20.20.0-0.4-0.4-0.3-0.5-0.60.80.8-0.7-0.8-0.8-0.8-0.7-0.7-0.81.0-0.6-0.5-0.7-0.7
Pavlov. Cond. latency score0.30.41.00.4-0.2-0.2-0.10.20.30.20.0-0.4-0.4-0.4-0.5-0.70.80.8-0.8-0.8-0.8-0.8-0.8-0.8-0.81.0-0.6-0.5-0.7-0.7
Pavlov. Cond. lever contacts0.40.52.0-0.70.70.80.8-0.7-0.7-0.70.80.60.60.70.60.5-0.4-0.40.50.50.50.50.50.50.41.4-1.0-1.0-1.0-1.0
Pavlov. Cond. magazine entry number1.21.52.8-1.21.01.01.0-1.1-1.1-1.00.81.21.21.21.31.5-1.6-1.61.61.71.71.71.61.61.7-0.2-0.2-0.20.0-0.0
Pavlov. Cond. intertrial magazine entries4.55.97.4-2.52.42.42.4-2.4-2.4-2.42.32.52.52.52.62.7-2.7-2.62.72.72.72.72.72.72.71.6-1.8-1.8-1.6-1.6
Pavlov. Cond. lever-magazine prob. diff.0.50.61.20.7-0.5-0.4-0.40.50.50.5-0.3-0.7-0.7-0.6-0.8-0.91.11.0-1.0-1.1-1.1-1.1-1.0-1.0-1.10.7-0.3-0.2-0.4-0.4
Pavlov. Cond. response bias0.10.21.3-0.30.40.40.4-0.4-0.3-0.40.50.30.30.30.20.2-0.1-0.10.10.10.10.10.10.10.01.1-0.7-0.6-0.7-0.7
Time in closed arm before self-admin1.31.51.81.3-1.3-1.3-1.31.31.31.3-1.2-1.3-1.3-1.3-1.3-1.31.11.2-1.3-1.3-1.3-1.3-1.2-1.2-1.3-1.21.11.01.11.0
Time in closed arm after self-admin0.70.71.01.0-0.9-0.9-0.90.90.90.9-0.8-0.9-0.9-0.9-0.9-0.90.81.0-0.8-0.8-0.8-0.8-0.8-0.8-1.0-0.60.60.60.70.6
Time in open arm before self-admin0.50.51.10.8-0.6-0.6-0.60.70.70.6-0.5-0.7-0.7-0.7-0.8-0.81.01.0-0.8-0.8-0.8-0.8-1.0-1.0-0.9-0.90.30.30.10.2
Time in open arm after self-admin0.20.30.3-0.60.50.50.5-0.5-0.5-0.50.50.50.50.50.50.5-0.4-0.50.50.40.40.40.40.40.50.2-0.5-0.5-0.6-0.6
Bone: periosteal estimation11.223.225.05.0-5.0-5.0-5.05.05.05.0-4.9-5.0-5.0-5.0-5.0-4.94.95.0-4.9-4.8-4.8-4.8-4.8-4.8-4.8-4.54.44.44.24.2
Bone: periosteal perimeter10.116.718.04.2-4.2-4.2-4.24.24.24.2-4.2-4.2-4.2-4.2-4.2-4.14.14.1-4.0-4.0-4.0-4.0-4.0-4.0-4.0-3.74.04.03.83.8
Bone: post-yield work9.512.913.83.6-3.7-3.7-3.73.73.73.7-3.7-3.7-3.7-3.7-3.7-3.73.63.5-3.6-3.6-3.6-3.6-3.6-3.6-3.5-3.43.43.43.23.2
Progressive ratio test 1 active lever presses6.77.08.5-2.72.82.82.8-2.8-2.8-2.82.92.72.72.72.62.5-2.4-2.42.42.42.42.42.42.42.32.7-2.9-2.8-2.9-2.8
Progressive ratio test 1 breakpoint6.06.37.4-2.62.72.72.7-2.6-2.6-2.62.72.62.62.62.52.4-2.3-2.32.32.32.32.32.32.32.32.5-2.6-2.6-2.7-2.6
Progressive ratio test 1 inactive lever presses3.23.54.7-2.11.91.91.9-1.9-1.9-1.91.92.02.02.02.02.0-2.0-2.22.01.91.91.91.91.92.11.5-1.5-1.5-1.4-1.3
Progressive ratio test 2 active lever presses2.73.03.4-1.81.81.81.8-1.8-1.8-1.81.71.81.81.81.81.8-1.7-1.81.81.81.81.81.81.81.81.4-1.4-1.4-1.4-1.3
Progressive ratio test 2 breakpoint3.43.84.3-2.12.02.02.0-2.0-2.0-2.01.92.02.02.02.02.0-2.0-2.02.12.12.12.12.12.12.01.6-1.6-1.6-1.5-1.6
Progressive ratio test 2 inactive lever presses2.32.63.6-1.81.61.61.6-1.6-1.7-1.61.51.71.71.71.71.8-1.8-1.91.81.81.81.81.81.81.91.2-1.0-1.0-1.0-0.8
Incentive Sensitization - Responses0.10.10.30.1-0.2-0.2-0.20.10.10.2-0.3-0.1-0.1-0.1-0.00.0-0.0-0.10.10.10.10.10.10.10.1-0.40.50.50.60.6
Incentive Sensitization - Breakpoint0.10.10.2-0.0-0.1-0.1-0.10.00.00.1-0.20.00.00.00.10.2-0.2-0.20.20.20.20.20.20.20.2-0.30.40.40.50.5
Sum of active levers in priming session hrs 5-60.10.10.7-0.20.30.30.4-0.3-0.3-0.30.40.20.20.20.20.1-0.1-0.10.0-0.1-0.1-0.1-0.0-0.00.10.8-0.6-0.5-0.7-0.5
Progressive ratio0.40.41.4-0.50.70.70.7-0.7-0.7-0.70.80.60.60.60.50.4-0.5-0.10.30.20.20.20.40.40.30.8-1.1-1.1-1.2-1.2
Food seeking constrained by brief footshock0.81.02.4-1.01.11.11.1-1.0-1.0-1.11.20.91.01.00.90.8-0.7-0.70.70.70.70.70.70.70.71.0-1.5-1.4-1.5-1.5
Seeking ratio, punishment vs. effort0.00.00.20.1-0.2-0.2-0.20.20.20.2-0.2-0.1-0.1-0.1-0.1-0.10.1-0.20.00.20.20.2-0.1-0.1-0.0-0.30.30.30.40.3
Retroperitoneal fat weight0.82.64.1-1.61.71.71.7-1.7-1.7-1.71.81.61.61.61.61.5-1.5-1.41.41.21.21.21.41.41.42.0-1.9-1.9-1.9-1.8
Reaction time number correct1.72.43.21.5-1.6-1.6-1.61.61.61.6-1.5-1.6-1.6-1.6-1.6-1.61.81.6-1.6-1.8-1.8-1.8-1.7-1.7-1.5-1.11.31.31.11.2
Reaction time mean minus median8.010.612.1-3.43.33.33.3-3.3-3.3-3.33.23.43.43.33.43.4-3.5-3.33.43.43.43.43.43.43.33.2-2.8-2.9-2.6-2.6
Reaction time mean minus median AUC5.67.38.3-2.82.72.72.7-2.7-2.7-2.72.72.82.82.82.82.8-2.9-2.82.82.82.82.82.82.82.72.8-2.4-2.4-2.2-2.2
Reaction time num false alarms1.62.22.4-1.51.61.51.5-1.6-1.6-1.51.51.61.61.51.61.5-1.5-1.31.51.51.51.51.51.51.41.5-1.3-1.3-1.2-1.2
Reaction time num false alarms AUC2.12.93.3-1.81.81.81.8-1.8-1.8-1.81.71.81.81.81.81.8-1.8-1.71.81.81.81.81.81.81.71.6-1.4-1.5-1.3-1.3
Reaction time trials correct on left1.72.43.21.5-1.6-1.6-1.61.61.61.6-1.5-1.6-1.6-1.6-1.6-1.61.81.6-1.6-1.8-1.8-1.8-1.7-1.7-1.5-1.11.31.31.11.2
Reaction time trials on left1.31.92.61.3-1.4-1.4-1.41.41.41.4-1.3-1.4-1.4-1.4-1.4-1.41.61.5-1.4-1.6-1.6-1.6-1.5-1.5-1.3-0.91.11.10.91.0
Reaction time mean0.81.11.3-1.01.11.11.1-1.1-1.1-1.11.11.11.11.11.11.0-1.0-1.01.11.11.11.11.01.01.01.0-0.9-0.9-0.9-0.8
Reaction time mean AUC0.40.60.8-0.80.80.80.8-0.8-0.8-0.80.80.80.80.80.80.8-0.8-0.70.90.80.80.80.70.70.80.7-0.7-0.6-0.7-0.6
Median of all reaction times0.00.00.00.00.10.00.1-0.0-0.0-0.00.10.00.00.00.0-0.00.00.00.10.00.00.0-0.1-0.1-0.00.10.00.0-0.10.0
Reaction time omissions9.613.114.8-3.83.73.73.7-3.7-3.7-3.73.73.83.83.73.83.7-3.6-3.73.83.73.73.73.63.63.73.2-3.3-3.3-3.1-3.1
Reaction time false alarm rate2.63.74.5-1.92.01.91.9-2.0-2.0-2.01.92.02.02.02.02.0-2.1-1.92.02.12.12.12.12.11.91.6-1.5-1.6-1.3-1.4
Reaction time premature initiation rate6.58.710.5-3.23.03.03.0-3.0-3.0-3.02.93.13.13.13.13.1-3.1-3.23.13.03.03.03.13.13.21.8-2.6-2.6-2.4-2.5
Reaction time premature initiations2.83.95.2-2.32.02.02.0-2.0-2.0-2.01.92.12.12.12.12.1-2.0-2.22.11.91.91.92.12.12.31.1-1.8-1.8-1.7-1.7
Std. dev. reaction times6.28.79.4-3.13.03.03.0-3.0-3.0-3.03.03.03.03.03.03.0-3.0-2.93.03.03.03.03.03.02.92.9-2.7-2.7-2.6-2.5
Reaction time trials completed1.31.92.61.3-1.4-1.4-1.41.41.41.4-1.3-1.4-1.4-1.4-1.4-1.41.61.5-1.4-1.6-1.6-1.6-1.5-1.5-1.3-0.91.11.10.91.0
Reaction time trials AUC2.13.04.01.7-1.8-1.8-1.81.81.81.8-1.7-1.8-1.8-1.8-1.8-1.82.01.8-1.8-2.0-2.0-2.0-1.9-1.9-1.7-1.21.41.51.31.3
Run reversals in cocaine runway, females0.10.10.50.2-0.4-0.4-0.40.30.30.4-0.5-0.2-0.3-0.3-0.2-0.10.1-0.1-0.10.00.00.0-0.1-0.10.0-0.60.70.70.70.7
Run reversals in cocaine runway, males1.51.41.7-1.21.11.11.1-1.2-1.2-1.11.11.21.21.21.21.2-1.2-1.21.21.21.21.21.21.21.21.3-1.2-1.2-0.8-1.2
Latency to leave start box in cocaine runway0.00.00.0-0.20.10.10.1-0.1-0.1-0.10.10.10.10.20.10.2-0.0-0.10.20.00.00.00.20.20.2-0.1-0.2-0.2-0.1-0.2
Latency to leave start box in cocaine runway, F1.92.02.4-1.51.51.51.5-1.5-1.5-1.51.51.51.51.51.51.5-1.2-1.41.41.31.31.31.51.51.41.0-1.4-1.4-1.3-1.4
Latency to leave start box in cocaine runway, M2.22.12.31.5-1.5-1.5-1.51.51.51.5-1.5-1.5-1.5-1.5-1.5-1.41.41.4-1.4-1.4-1.4-1.4-1.4-1.4-1.4-1.21.41.41.51.4
Std. dev. time between licks in bursts1.41.72.0-1.41.41.41.3-1.4-1.4-1.41.31.31.31.31.31.3-1.4-1.11.31.31.31.31.31.31.30.9-1.3-1.3-1.3-1.3
Total sessions with >9 infusions1.61.82.0-1.41.41.41.4-1.4-1.4-1.41.41.41.41.41.41.4-1.4-1.31.41.41.41.41.41.41.31.3-1.0-0.9-1.2-0.9
Short access day 1 total inactive lever presses1.71.82.1-1.51.41.41.4-1.4-1.4-1.41.41.41.41.41.41.4-1.4-1.41.41.41.41.41.41.41.41.2-1.1-1.1-1.1-1.0
Short access day 10 total inactive lever presses0.00.00.1-0.20.00.00.0-0.1-0.1-0.0-0.00.10.10.10.10.2-0.3-0.40.20.20.20.20.20.20.30.10.20.10.30.2
Short access day 1 total infusions0.30.30.6-0.60.60.70.7-0.6-0.6-0.60.70.60.60.60.50.5-0.4-0.40.50.40.40.40.50.50.40.6-0.6-0.6-0.8-0.6
Short access day 10 total infusions1.92.22.8-1.51.61.61.6-1.5-1.5-1.61.61.51.51.51.41.3-1.3-1.31.31.31.31.31.31.31.31.6-1.6-1.6-1.7-1.6
Short access total infusions1.31.51.9-1.21.31.31.3-1.3-1.3-1.31.41.21.21.21.21.1-1.1-1.01.11.11.11.11.11.11.01.2-1.2-1.2-1.4-1.2
Short access day 1 locomotion0.20.20.3-0.50.50.50.5-0.5-0.5-0.50.50.50.50.50.50.5-0.4-0.50.50.40.40.40.50.50.50.5-0.4-0.4-0.5-0.4
Short access day 10 total locomotion0.10.10.2-0.40.40.40.4-0.4-0.4-0.40.40.40.40.40.40.3-0.2-0.40.30.30.30.30.30.30.40.3-0.4-0.4-0.4-0.3
Short access total locomotion0.50.60.7-0.80.80.80.8-0.8-0.8-0.80.80.80.80.80.80.7-0.7-0.90.70.70.70.70.70.70.80.8-0.7-0.7-0.7-0.6
One hour access (0.3 mA shock)0.30.40.9-0.50.40.40.4-0.4-0.4-0.40.30.50.50.50.60.7-0.8-0.80.80.90.90.90.80.80.8-0.10.30.30.30.4
Compulsive drug intake1.61.62.11.3-1.3-1.3-1.31.31.31.3-1.3-1.3-1.3-1.3-1.2-1.21.11.2-1.1-1.1-1.1-1.1-1.1-1.1-1.2-1.21.41.41.41.4
One hour access (shock baseline)0.30.30.5-0.60.40.40.4-0.5-0.5-0.40.30.50.50.50.60.7-0.7-0.70.70.70.70.70.70.70.7-0.00.10.10.10.2
Social response proportion0.20.20.3-0.40.40.40.4-0.4-0.4-0.40.40.40.40.40.40.5-0.5-0.50.40.60.60.60.50.50.50.3-0.4-0.4-0.3-0.4
Social responses7.910.111.1-3.33.23.23.2-3.3-3.3-3.23.13.33.33.33.33.3-3.3-3.33.23.33.33.33.33.33.33.0-2.8-2.9-2.5-2.7
Social time0.10.10.40.2-0.3-0.3-0.30.30.30.3-0.4-0.2-0.2-0.2-0.2-0.10.2-0.2-0.1-0.0-0.0-0.0-0.1-0.10.0-0.60.60.60.60.6
Soleus weight0.82.43.31.5-1.6-1.6-1.61.61.61.6-1.7-1.5-1.6-1.6-1.5-1.41.41.2-1.4-1.4-1.4-1.4-1.4-1.4-1.4-1.81.81.81.81.8
Bone: stiffness18.629.432.05.6-5.6-5.6-5.65.65.65.6-5.7-5.6-5.6-5.6-5.5-5.45.25.3-5.2-5.3-5.3-5.3-5.2-5.2-5.2-5.55.45.45.25.2
Tibialis anterior weight1.55.010.92.0-2.4-2.4-2.42.32.32.3-2.6-2.1-2.1-2.1-1.9-1.71.41.4-1.4-1.5-1.5-1.5-1.5-1.5-1.4-3.33.23.23.23.3
Time to tail flick, vehicle, before self-admin0.80.81.0-0.90.90.90.9-0.9-0.9-0.90.90.90.90.90.90.9-1.0-0.80.91.01.01.00.90.90.70.8-0.8-0.7-0.9-0.7
Time to tail flick, vehicle, after self-admin0.40.41.00.6-0.7-0.7-0.70.70.70.7-0.7-0.6-0.6-0.6-0.6-0.60.60.5-0.5-0.6-0.6-0.6-0.5-0.5-0.4-1.00.70.60.80.7
Time to tail flick, test, before self-admin0.10.10.3-0.50.40.40.4-0.4-0.4-0.40.40.40.40.40.40.4-0.4-0.60.40.30.30.30.30.30.50.0-0.3-0.3-0.4-0.3
Time to tail flick, test, after self-admin0.50.51.10.7-0.7-0.7-0.70.70.70.7-0.8-0.6-0.7-0.7-0.6-0.50.50.5-0.5-0.6-0.6-0.6-0.5-0.5-0.5-1.11.01.00.91.0
Delta time to tail flick, vehicle, before/after SA0.50.50.80.6-0.8-0.8-0.80.80.80.8-0.8-0.7-0.7-0.7-0.7-0.60.60.5-0.7-0.8-0.8-0.8-0.7-0.7-0.4-0.90.70.70.90.7
Delta time to tail flick, test, before/after SA0.30.30.90.5-0.6-0.6-0.60.60.60.6-0.7-0.5-0.5-0.5-0.5-0.40.30.4-0.3-0.3-0.3-0.3-0.2-0.2-0.4-0.50.80.80.90.8
Tibia length6.117.320.84.3-4.2-4.2-4.24.34.34.2-4.1-4.3-4.3-4.3-4.3-4.44.34.6-4.3-4.3-4.3-4.3-4.4-4.4-4.3-3.53.53.53.43.3
Ambulatory time before self-admin4.14.24.9-2.22.22.22.2-2.2-2.2-2.22.22.12.12.12.12.0-1.8-2.01.91.91.91.92.02.02.11.9-2.1-2.0-2.1-2.0
Ambulatory time after self-admin2.02.22.9-1.51.61.51.6-1.6-1.5-1.51.51.51.51.51.51.5-1.5-1.41.41.51.51.51.51.51.51.7-1.4-1.3-1.4-1.2
Bone: tissue strength1.91.92.51.4-1.4-1.4-1.41.41.41.4-1.4-1.4-1.4-1.4-1.4-1.31.31.2-1.3-1.4-1.4-1.4-1.3-1.3-1.2-1.61.41.41.41.4
Total heroin consumption1.82.12.41.5-1.5-1.4-1.41.51.51.5-1.4-1.5-1.5-1.5-1.5-1.51.61.6-1.6-1.6-1.6-1.6-1.5-1.5-1.6-1.41.11.11.01.1
Bone: trabecular number6.19.612.13.2-3.1-3.1-3.13.23.23.1-3.0-3.2-3.2-3.2-3.2-3.33.23.5-3.2-3.2-3.2-3.2-3.2-3.2-3.2-2.52.62.62.42.4
Bone: trabecular spacing2.32.93.7-1.71.71.71.7-1.7-1.7-1.71.61.81.81.81.81.8-1.8-1.91.81.81.81.81.81.81.81.7-1.3-1.3-1.2-1.2
Bone: trabecular thickness0.20.21.1-0.0-0.2-0.2-0.20.10.10.1-0.30.00.00.00.10.3-0.4-0.20.40.40.40.40.40.40.5-1.10.80.70.80.8
Bone: trabecular tissue density0.20.31.30.1-0.3-0.3-0.30.20.20.3-0.5-0.1-0.1-0.10.00.2-0.4-0.20.30.30.30.30.30.30.3-0.71.01.01.11.2
Water consumed over 24 hours0.00.00.20.10.10.10.1-0.1-0.1-0.10.1-0.00.00.0-0.0-0.10.10.2-0.1-0.1-0.1-0.1-0.1-0.1-0.20.2-0.4-0.4-0.4-0.4
Number of responses in last shaping day0.10.10.70.2-0.3-0.3-0.30.30.30.3-0.4-0.2-0.2-0.2-0.1-0.1-0.10.00.00.00.00.00.00.0-0.0-0.40.80.80.70.8