Hub : Genes

LOC102552777

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 NAcc alternative polyA XR_005488673.1 0.05 0.04 1.4e-04 0.02 0.03 0.03 0.01 4.0e-03 6.6e-04 3.4e-04 7.3e-03
2 Liver alternative polyA XR_005488670.1 0.05 0.03 7.0e-03 0.02 0.01 -0 0.01 2.6e-03 2.0e-02 4.2e-01 7.7e-03
3 NAcc isoform ratio XR_005488672.1 0.02 0.01 7.6e-03 0.02 0.02 0.01 0.01 5.5e-03 1.7e-03 1.5e-02 9.6e-03
4 NAcc gene expression LOC102552777 0.02 0.01 6.4e-03 0.01 0.02 0.02 0.01 5.5e-02 4.7e-03 4.8e-03 4.2e-02
5 OFC alternative polyA XR_005488665.1 0.24 0.12 8.8e-03 0.05 0.12 0.04 0.1 2.5e-02 6.9e-04 3.5e-02 2.3e-03
6 pVTA gene expression LOC102552777 0.13 0.08 4.3e-03 0.01 0.02 0.01 0.01 6.8e-02 3.9e-02 1.4e-01 6.9e-02
7 Adipose alternative polyA XR_005488670.1 0.05 0.03 1.9e-03 0.01 0.03 0.02 0.02 7.4e-03 2.9e-04 1.1e-03 2.2e-03
8 OFC alternative polyA XR_005488665.1 0.25 0.12 7.4e-03 0.07 0.14 0.09 0.14 9.3e-03 4.0e-04 4.1e-03 2.8e-04
9 Adipose gene expression LOC102552777 0.07 0.04 3.1e-05 0.02 0.04 0.03 0.03 4.5e-03 2.4e-05 4.8e-04 4.7e-04
10 PL gene expression LOC102552777 0.07 0.03 3.7e-07 0.05 0.06 0.06 0.05 4.7e-06 1.2e-07 4.7e-07 1.2e-06
11 BLA gene expression LOC102552777 0.11 0.05 2.6e-04 0.03 0.04 0.04 0.04 1.6e-02 1.9e-03 4.6e-03 3.6e-03
12 Brain gene expression LOC102552777 0.04 0.02 4.6e-03 0 0.02 0.01 0 1.8e-01 9.2e-03 4.0e-02 9.5e-02

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12
Bone: apparent density0.40.72.41.21.61.2-0.9-0.4-0.40.2-0.6-0.4-0.11.10.6
Area under the delay curve0.20.20.91.00.70.4-0.4-0.2-0.30.30.00.20.10.70.4
BMI with tail2.27.126.6-5.2-2.8-3.73.41.12.6-2.60.72.71.6-0.60.3
BMI without tail2.65.414.9-3.0-3.6-0.71.33.92.3-0.63.40.02.4-0.31.8
Body weight1.46.034.4-5.9-1.7-3.52.70.21.7-2.1-0.62.00.3-1.7-0.8
Weight adjusted by age1.71.94.2-1.01.2-1.0-0.4-1.8-0.90.3-1.80.4-1.9-1.8-2.1
Bone surface0.50.82.41.31.51.5-1.1-0.5-0.50.5-0.6-0.8-0.20.90.3
Bone volume0.30.41.40.81.21.0-0.7-0.2-0.10.2-0.4-0.40.10.90.5
Breakpoint value in progressive ratio session0.40.42.60.41.60.5-0.5-0.5-0.1-0.1-0.80.2-0.00.80.4
Number of licking bursts0.50.62.01.20.40.6-0.6-0.7-1.40.8-0.2-0.5-0.8-0.2-0.6
Context. condit. distance diff. score0.10.10.3-0.2-0.1-0.40.3-0.10.5-0.5-0.60.50.30.40.3
Locomotion velocity, session 12.62.87.3-2.7-2.6-1.81.52.01.8-0.71.50.91.3-0.90.5
Locomotion distance, session 12.73.410.0-2.8-3.2-2.41.72.01.9-0.71.31.21.2-1.30.0
Locomotion velocity, session 24.65.411.2-3.0-3.3-3.33.01.52.2-2.01.12.72.00.10.9
Locomotion distance, session 23.85.314.3-2.6-3.8-2.82.82.22.5-1.61.72.12.3-0.01.0
Locomotion velocity, session 31.01.12.9-0.1-1.7-0.70.71.51.1-0.31.50.81.30.41.1
Locomotion distance, session 30.10.20.40.4-0.1-0.0-0.3-0.2-0.20.5-0.2-0.4-0.5-0.7-0.7
Stereotopy head waving bouts, day 32.53.05.72.31.31.9-2.3-0.7-2.42.10.2-1.9-1.8-1.0-1.2
Stereotopy head waving duration, day 30.60.71.41.0-0.10.7-1.00.2-1.11.21.0-0.9-0.8-0.9-0.5
Locomotion velocity, session 71.92.16.9-1.1-2.6-0.61.12.31.5-0.51.40.41.80.41.4
Locomotion distance, session 70.10.20.9-0.2-0.90.10.00.70.20.30.3-0.60.1-0.5-0.1
Stereotopy head waving bouts, day 70.80.92.51.60.30.9-1.50.8-0.81.50.7-0.6-0.3-0.30.2
Stereotopy head waving duration, day 70.80.92.31.50.20.9-0.91.20.10.71.2-0.00.80.91.4
Locomotion velocity, session 83.03.610.0-2.3-3.2-2.11.82.51.7-0.71.51.72.0-0.01.3
Locomotion distance, session 82.23.26.9-2.0-2.6-2.22.21.52.1-1.50.81.91.90.41.0
Degree of sensitization distance0.20.20.4-0.3-0.50.20.40.60.5-0.50.3-0.00.60.50.7
Degree of sensitization stereotypy0.10.10.3-0.1-0.1-0.4-0.30.60.00.4-0.00.50.2-0.10.3
Conditioned locomotion0.50.61.70.6-1.20.3-0.41.1-0.41.21.3-0.60.2-0.6-0.0
Cocaine response after cond. corrected3.13.57.6-0.2-1.3-0.82.01.22.8-2.21.21.52.62.42.3
Cocaine response after cond. not corrected3.84.29.00.2-1.4-0.31.91.62.8-2.21.31.43.02.92.9
Cocaine response before conditioning0.50.61.41.2-0.51.2-0.80.8-0.50.90.7-1.10.10.10.4
Saline control response0.60.72.6-1.6-1.3-1.01.20.10.5-0.8-0.50.60.60.10.0
Bone: connectivity density0.30.41.41.20.90.9-0.7-0.1-0.20.3-0.0-0.20.21.00.6
Bone: cortical apparent density0.40.51.8-1.1-0.9-1.30.40.2-0.30.1-0.10.8-0.2-1.0-0.5
Bone: cortical area1.62.45.4-2.0-0.3-2.22.0-0.61.4-2.0-1.42.30.90.80.3
Bone: cortical porosity0.20.20.6-0.2-0.1-0.60.6-0.30.1-0.4-0.70.80.30.50.2
Bone: cortical porosity0.50.51.3-0.5-0.4-0.91.0-0.40.3-0.9-0.81.10.60.90.4
Bone: cortical thickness1.21.94.5-1.3-0.4-1.71.8-0.41.2-1.8-1.32.11.11.40.9
Bone: cortical thickness0.20.30.9-0.00.8-0.1-0.0-0.6-0.5-0.2-0.90.6-0.10.60.3
Bone: cortical tissue density0.40.62.0-1.2-1.0-1.40.50.2-0.20.0-0.10.8-0.2-1.0-0.5
Condit. Reinf. active minus inactive responses0.60.72.20.31.5-0.30.2-1.30.2-0.9-1.30.8-0.30.70.0
Condit. Reinf. active-inactive response ratio0.80.82.5-0.50.8-0.90.8-0.90.8-1.4-1.61.10.10.60.2
Condit. Reinf. active responses0.40.52.31.10.60.20.4-0.30.3-0.70.10.70.71.51.0
Condit. Reinf. inactive responses0.70.92.71.5-0.21.1-0.50.9-0.30.71.7-0.50.60.90.9
Incentive salience index mean1.11.43.2-0.21.0-1.21.3-1.50.5-1.7-1.41.80.31.30.3
Condit. Reinf. lever presses1.82.46.2-1.3-1.1-2.22.5-0.51.2-2.1-0.12.31.21.20.6
Condit. Reinf. active minus inactive responses0.30.41.50.41.21.2-0.80.10.2-0.00.2-0.60.10.60.7
Condit. Reinf. active-inactive response ratio0.20.20.8-0.90.30.10.00.40.7-0.40.5-0.10.2-0.10.3
Condit. Reinf. active responses0.81.12.91.51.01.7-0.90.40.4-0.10.4-0.60.61.61.4
Condit. Reinf. inactive responses1.21.46.52.50.41.8-1.10.6-0.20.60.6-0.70.61.51.3
Condit. Reinf. lever presses1.01.34.51.41.81.1-0.2-1.10.4-1.1-1.10.20.32.11.1
Condit. Reinf. lever reinforcers received0.81.13.11.41.31.6-0.80.10.5-0.40.0-0.40.61.81.4
Conditioned reinforcement - actives0.20.20.5-0.6-0.40.3-0.40.50.20.30.2-0.7-0.1-0.6-0.2
Conditioned reinforcement - inactives0.60.61.8-1.2-1.1-0.50.70.91.3-0.60.60.00.7-0.40.2
Conditioned locomotion0.40.52.9-1.7-0.1-0.90.6-0.20.7-0.8-0.70.4-0.0-0.4-0.3
Patch foraging indifference point 0 sec0.50.81.9-0.6-1.1-0.30.81.00.9-0.60.10.81.41.21.4
Patch foraging indifference point AUC0.60.64.6-2.1-0.9-0.90.90.30.4-0.40.00.40.4-0.4-0.2
Delay disc. indifference point, 0s delay0.40.51.31.11.11.0-0.6-0.2-0.10.1-0.2-0.30.21.00.6
Delay disc. indifference point, 16s delay0.10.10.40.60.5-0.30.0-0.7-0.40.0-0.30.5-0.30.2-0.2
Delay disc. indifference point, 2s delay0.40.51.90.8-0.00.50.20.50.4-0.40.50.20.91.41.2
Delay disc. indifference point, 24s delay0.30.30.80.80.4-0.2-0.1-0.9-0.80.3-0.50.4-0.6-0.1-0.5
Delay disc. indifference point, 4s delay2.12.25.01.4-0.30.70.31.51.8-0.61.90.52.12.22.2
Delay disc. indifference point, 8s delay1.41.43.00.51.40.3-1.1-1.5-1.71.1-1.3-0.4-1.6-0.8-1.4
Indifference point function ln k1.11.64.42.11.51.3-1.6-0.7-1.31.2-0.7-1.2-1.3-0.6-0.7
Indifference point function log k1.11.64.42.11.51.3-1.6-0.7-1.31.2-0.7-1.2-1.3-0.6-0.7
Patch foraging total patch changes 0 sec0.61.01.9-0.8-1.0-0.61.00.80.9-0.9-0.11.11.41.31.3
Patch foraging total patch changes 12 sec1.01.35.6-2.4-1.2-1.61.30.30.9-0.8-0.51.30.8-0.00.1
Patch foraging total patch changes 18 sec0.30.42.1-1.4-0.7-0.40.00.6-0.60.7-0.1-0.0-0.0-0.7-0.3
Patch foraging total patch changes 24 sec0.10.10.5-0.7-0.1-0.20.2-0.3-0.3-0.10.00.1-0.3-0.3-0.4
Patch foraging total patch changes 6 sec0.30.51.5-1.1-1.0-0.10.11.20.40.20.20.20.90.40.9
Patch foraging time to switch 0 sec0.10.10.60.6-0.1-0.1-0.10.40.20.20.80.20.30.10.3
Patch foraging water rate 0 sec0.10.10.3-0.30.30.30.00.20.6-0.40.1-0.10.40.50.5
Patch foraging water rate 12 sec0.10.20.4-0.5-0.0-0.20.20.40.4-0.40.30.40.50.40.6
Patch foraging water rate 18 sec0.10.10.3-0.5-0.5-0.20.30.50.3-0.30.40.20.3-0.00.4
Patch foraging water rate 24 sec0.20.30.80.30.70.8-0.90.1-0.70.6-0.4-0.5-0.4-0.10.1
Patch foraging water rate 6 sec0.10.10.60.20.50.6-0.10.00.1-0.30.0-0.00.20.70.7
Seeking ratio, delayed vs. immediate footshock0.20.30.7-0.4-0.8-0.90.40.50.3-0.00.30.90.50.00.2
Distance traveled before self-admin1.61.83.7-1.8-1.4-1.71.90.41.4-1.60.01.51.20.60.7
Distance traveled after self-admin1.61.84.3-2.00.7-2.11.3-1.40.4-1.3-1.71.6-0.5-0.6-1.0
Extensor digitorum longus weight0.93.611.4-3.4-2.5-2.92.70.41.4-1.7-0.12.01.0-0.5-0.2
Bone: elastic displacement1.01.12.3-1.1-0.1-1.51.3-1.40.3-1.2-1.51.0-0.4-0.3-1.0
Bone: elastic work0.60.82.3-0.70.7-1.00.9-1.50.4-1.2-1.50.8-0.40.1-0.7
Bone: endosteal estimation0.30.61.8-1.1-0.7-0.70.90.61.3-0.80.60.50.80.20.4
Bone: endosteal perimeter0.81.76.5-2.6-0.7-2.01.6-0.21.3-1.4-0.81.40.5-0.2-0.2
Epididymis fat weight0.40.93.5-1.9-1.3-1.11.01.00.8-0.30.70.50.7-0.60.1
Delta time in closed arm before/after self-admin1.21.23.5-1.20.5-1.40.5-1.5-0.4-0.3-1.91.0-1.0-0.8-1.3
Delta time in open arm before/after self-admin1.41.45.0-0.1-2.2-0.1-0.02.20.70.81.9-0.41.1-0.60.6
Diff in mean of infusions in LGA sessions0.70.83.31.81.31.2-1.0-0.6-0.40.60.2-0.9-0.60.0-0.3
Delay discount exponential model param0.20.31.1-1.0-0.4-0.40.3-0.10.0-0.2-0.3-0.2-0.4-0.9-0.6
Extinction: sum of active levers before priming0.90.93.1-0.71.2-0.8-0.0-1.3-0.8-0.1-1.80.6-1.0-0.6-1.0
Active lever presses in extinction session 61.21.25.7-2.4-0.3-1.50.9-0.60.0-0.4-1.20.5-0.5-1.2-1.3
Bone: final force0.30.51.50.30.5-0.20.6-0.10.9-0.9-0.20.90.81.20.9
Bone: final moment0.30.51.50.20.7-0.20.5-0.20.8-0.9-0.30.90.71.20.8
Food consumed during 24 hour testing period0.30.31.61.30.90.5-0.1-0.40.4-0.50.3-0.10.00.60.3
Glucose0.91.32.6-0.9-1.0-1.21.60.51.4-1.40.31.51.30.91.0
Heart weight1.42.05.7-1.41.5-0.80.2-2.4-0.8-0.6-2.20.4-1.7-0.9-1.7
Delay discount hyperbolic model param0.30.41.2-1.1-0.4-0.50.2-0.3-0.2-0.1-0.5-0.2-0.6-1.1-0.9
Intermittent access intake day 1-15 change0.30.31.5-1.2-0.7-0.30.00.2-0.20.30.2-0.3-0.3-1.0-0.7
Intermittent access intake escalation0.30.31.6-1.2-0.6-0.50.20.30.10.10.2-0.1-0.2-0.9-0.5
Intermittent access intake escalation 20.30.31.0-0.4-0.20.0-0.4-0.0-0.60.70.0-0.6-0.6-1.0-0.8
Intermitt. access day 1 inactive lever presses0.50.61.7-1.3-1.2-1.00.50.1-0.60.5-0.70.3-0.2-0.9-0.7
Intermitt. access day 15 inactive lever presses0.50.51.3-0.8-0.1-0.2-0.4-0.4-1.20.8-0.9-0.2-0.9-0.9-0.8
Intermitt. access escalation Index2.42.14.21.7-1.31.6-0.32.00.70.11.9-0.91.61.52.0
Intermittent access day 1 total infusions0.50.62.1-1.2-0.8-0.60.60.71.4-0.80.10.20.6-0.20.3
Intermittent access day 15 total infusions0.70.82.5-1.3-1.2-0.30.41.31.6-0.60.8-0.20.8-0.40.4
Intermittent access terminal intake (last 3 days)0.40.41.8-1.3-0.7-0.40.30.61.0-0.40.1-0.30.2-0.7-0.1
Intermittent access total infusions0.91.03.5-1.5-1.2-0.91.00.81.9-1.10.30.30.8-0.20.3
Intermittent access day 1 locomotion0.70.83.5-1.9-0.7-1.00.90.41.2-1.0-0.50.60.5-0.20.2
Intermittent access day 15 total locomotion1.92.17.2-2.7-0.7-1.61.60.62.1-1.8-0.31.51.20.40.8
Intermittent access total locomotion1.21.36.1-2.5-1.0-1.61.20.51.3-1.1-0.61.10.7-0.30.2
Intermittent access standard deviation0.40.51.2-1.10.4-0.7-0.1-0.6-0.10.1-0.90.3-0.8-1.0-0.9
Left kidney weight1.43.917.4-4.2-2.4-3.02.40.61.0-1.3-0.61.90.7-1.1-0.4
Right kidney weight2.15.821.3-4.6-2.5-3.73.20.51.8-2.3-0.42.61.2-0.6-0.1
Cocaine induced anxiety0.91.12.71.41.70.6-0.7-1.6-1.30.3-1.4-0.0-0.90.6-0.3
Post-drug Anxiety1.41.63.51.91.71.2-1.3-1.5-1.60.9-1.1-0.8-1.30.1-0.7
Baseline Anxiety0.30.30.60.50.20.4-0.6-0.3-0.60.8-0.1-0.6-0.6-0.6-0.7
Tail length0.41.34.6-0.3-0.91.4-0.72.10.30.71.8-1.60.7-0.30.9
Length with tail0.20.62.2-1.50.9-0.2-0.2-0.7-0.5-0.0-1.1-0.2-0.9-0.9-0.9
Length without tail2.24.713.9-1.82.1-1.90.6-3.6-1.1-0.8-3.71.3-2.3-1.3-2.7
Times rat made contact with spout1.11.23.1-0.70.8-1.31.1-1.80.6-1.5-1.61.4-0.20.4-0.4
Lifetime Intake0.50.62.3-1.3-1.0-0.50.60.81.5-0.80.2-0.00.6-0.30.2
Liver weight, left0.40.61.1-0.5-1.0-0.50.80.90.9-0.60.60.61.10.50.9
Liver weight, right2.33.86.9-2.2-2.6-1.82.21.92.6-1.81.01.72.30.81.7
Locomotor activity0.10.20.7-0.4-0.60.6-0.20.6-0.20.10.5-0.80.0-0.30.1
Locomotor testing distance0.30.61.6-0.1-0.80.9-0.71.0-0.50.80.9-1.3-0.1-0.7-0.0
Locomotor testing rearing0.81.34.4-0.5-2.00.5-0.32.10.80.61.7-1.20.7-0.80.4
Locomotion in novel chamber0.60.82.31.50.91.3-1.00.0-1.10.8-0.4-0.5-0.10.80.6
Locomotion in novel chamber post-restriction1.01.23.41.80.81.8-0.40.20.5-0.40.5-0.90.81.81.3
Fecal boli incidents, locomotor time 11.31.53.60.6-1.60.30.51.70.5-0.11.40.41.71.51.9
Change in fecal boli incidents, locomotor task0.30.30.8-0.2-0.5-0.50.50.70.6-0.20.90.60.70.20.5
Time >=10cm from walls, locomotor time 10.40.41.3-1.1-0.2-1.10.8-0.30.1-0.5-0.61.10.10.1-0.0
Bouts of movement, locomotor time 10.30.31.10.40.30.8-0.40.5-0.40.30.0-0.10.51.01.0
Total resting periods, locomotor time 10.30.31.00.4-0.10.6-0.20.6-0.30.30.10.10.61.01.0
Rest time, locomotor task time 10.50.61.4-1.0-0.2-1.10.5-0.8-0.7-0.1-1.21.1-0.3-0.0-0.4
Distance moved, locomotor task time 10.60.72.3-0.3-0.80.20.41.21.5-0.61.3-0.40.90.10.7
Vertical activity count, locomotor time 10.30.31.0-0.90.6-0.10.3-0.20.9-1.0-0.60.10.10.30.2
Time >=10cm from walls, locomotor time 20.30.41.10.90.7-0.1-0.0-1.1-0.6-0.0-1.00.3-0.50.2-0.4
Bouts of movement, locomotor time 20.70.82.00.0-0.40.0-0.7-0.3-1.41.4-0.3-0.6-1.1-1.4-1.3
Total resting periods, locomotor time 21.21.23.1-0.2-0.10.0-0.9-0.6-1.81.5-0.7-0.7-1.5-1.6-1.6
Rest time, locomotor task time 20.70.83.0-0.5-0.20.1-0.8-0.1-1.71.5-0.6-0.4-0.9-1.0-0.8
Distance moved, locomotor task time 20.70.83.7-0.10.20.10.60.61.9-1.30.60.31.11.01.1
Vertical activity count, locomotor time 20.60.61.9-0.61.3-0.10.4-0.71.0-1.4-0.80.50.20.90.5
Light reinforcement 11.22.25.7-1.0-0.2-0.51.50.42.4-2.30.51.21.71.91.7
Light reinforcement 20.81.02.8-1.30.7-1.11.1-0.81.3-1.7-0.61.30.40.70.3
Bone: marrow area0.30.61.8-1.2-0.8-0.81.00.61.3-0.90.50.60.80.20.4
Bone: maximum diameter2.13.87.3-2.7-1.7-2.62.60.62.3-2.2-0.42.51.80.91.0
Bone: maximum force0.40.71.6-0.60.1-0.81.1-0.50.9-1.3-0.81.20.71.00.5
Bone: maximum moment0.40.81.7-0.70.3-0.91.0-0.60.8-1.3-0.91.20.61.00.4
Mean time between licks in bursts1.31.85.1-0.61.3-0.9-0.1-2.3-1.60.2-2.00.6-1.7-1.0-1.8
Mean num. licks in bursts1.41.73.9-2.00.3-1.71.4-0.81.5-2.0-1.11.70.40.40.1
Cd content in liver0.90.92.2-0.30.8-0.71.0-0.81.1-1.5-0.81.30.71.30.6
Co content in liver0.20.31.0-0.5-0.1-1.00.4-0.40.1-0.1-0.70.7-0.3-0.6-0.6
Cu content in liver0.81.03.90.62.01.1-0.8-1.2-0.4-0.2-1.5-0.3-0.51.00.2
Fe content in liver1.11.35.21.12.31.4-1.5-1.2-0.80.5-1.0-0.9-1.10.2-0.4
K content in liver5.15.010.70.4-2.90.21.62.92.4-1.22.70.43.32.43.1
Mg content in liver2.22.35.00.1-2.2-0.11.31.81.6-0.91.50.62.21.72.0
Mn content in liver1.51.74.0-0.4-2.0-0.81.21.71.4-0.71.70.81.70.71.3
Na content in liver1.41.54.50.8-1.11.3-0.52.10.70.71.6-1.01.40.81.5
Rb content in liver0.50.71.61.3-0.21.1-0.30.70.6-0.10.7-0.60.81.11.1
Se content in liver1.11.35.22.30.41.7-0.80.80.00.51.2-0.70.71.41.3
Sr content in liver0.70.61.40.9-0.20.9-1.01.1-0.31.11.2-0.70.1-0.20.4
Zn content in liver0.30.40.90.1-1.00.6-0.20.80.00.50.9-0.90.3-0.30.1
Bone: minimum diameter0.40.71.7-1.11.2-0.80.2-1.10.2-0.5-1.30.7-0.6-0.4-0.7
Time in familiar zone, hab. session 13.73.57.61.71.42.1-2.80.2-1.72.60.8-2.6-1.8-1.9-1.3
Time in novel zone, hab. session 11.71.73.6-1.7-0.6-1.61.9-0.70.9-1.9-1.21.80.71.00.4
Total zone transitions, hab. session 12.23.19.2-1.4-3.0-1.51.42.61.8-0.51.81.12.10.11.4
Total locomotion distance, hab. session 10.91.25.6-0.4-2.4-0.50.11.90.11.01.5-0.30.5-1.20.1
Locomotion velocity, hab. session 11.42.09.0-0.7-3.0-0.90.52.50.60.82.00.11.1-1.00.4
Time in familiar zone, hab. session 22.02.15.11.01.01.9-2.30.3-1.62.10.2-2.0-1.3-1.1-0.7
Time in novel zone, hab. session 21.71.74.6-1.6-0.6-2.12.0-0.90.9-1.8-0.91.90.40.2-0.2
Total zone transitions, hab. session 22.63.47.1-1.7-2.7-2.02.02.12.3-1.21.51.72.10.41.4
Total locomotion distance, hab. session 21.21.55.5-0.7-2.4-0.60.42.30.70.61.90.11.1-0.70.6
Locomotion velocity, hab. session 21.41.96.5-0.8-2.6-0.80.62.51.00.32.10.31.4-0.50.8
Novel to familiar place preference ratio0.50.51.60.70.40.1-0.3-0.9-1.30.7-0.6-0.4-0.9-0.5-1.0
Novelty place preference0.91.02.60.40.60.1-0.5-1.2-1.60.9-0.9-0.5-1.3-1.0-1.4
Time in novel zone, NPP test1.51.53.90.40.80.1-0.7-1.5-2.01.1-1.2-0.6-1.7-1.3-1.8
Total zone transitions, NPP test3.65.213.4-2.8-3.7-2.93.01.72.3-1.91.02.22.20.21.0
Total locomotion distance, NPP test2.02.710.5-1.0-3.2-1.21.52.41.4-0.42.00.81.90.11.2
Locomotion velocity, NPP test2.43.410.4-1.0-3.2-1.21.82.61.8-0.82.11.12.30.61.7
Intraocular pressure0.20.31.1-0.8-1.1-0.30.40.60.5-0.20.8-0.10.2-0.5-0.0
Delta distance traveled before/after self-admin1.51.63.7-0.61.3-0.8-0.2-1.9-1.00.1-1.60.2-1.7-1.5-1.9
Delta ambulatory time before/after self-admin0.70.82.0-0.50.8-0.90.0-1.3-0.5-0.0-1.00.3-1.2-1.2-1.4
Parametrial fat weight0.40.81.5-0.3-0.4-0.40.80.61.2-1.01.00.91.21.11.2
Pavlov. Cond. lever latency0.50.72.00.10.21.1-1.31.00.40.80.8-1.4-0.3-0.9-0.0
Pavlov. Cond. magazine entry latency1.11.43.7-1.20.5-1.60.9-1.9-0.5-0.6-1.61.0-1.0-0.8-1.6
Pavlov. Cond. change in total contacts0.40.41.3-0.20.0-1.00.8-0.60.3-0.7-0.61.20.30.50.0
Pavlov. Cond. index score0.81.12.9-0.70.4-1.41.1-1.7-0.5-0.8-1.51.4-0.40.2-0.8
Pavlov. Cond. latency score0.81.02.5-0.80.2-1.51.3-1.6-0.4-0.9-1.31.4-0.30.1-0.8
Pavlov. Cond. lever contacts0.60.72.0-0.10.0-1.11.2-1.2-0.3-0.9-1.01.40.10.8-0.1
Pavlov. Cond. magazine entry number1.41.74.61.0-1.01.4-0.42.21.10.11.9-0.91.51.11.9
Pavlov. Cond. intertrial magazine entries1.72.16.72.61.82.2-2.0-0.2-1.21.30.2-1.4-0.60.50.3
Pavlov. Cond. lever-magazine prob. diff.0.81.02.8-0.60.5-1.41.1-1.7-0.5-0.7-1.51.4-0.40.3-0.7
Pavlov. Cond. response bias0.70.83.00.01.0-0.90.5-1.7-0.7-0.5-1.51.1-0.60.3-0.7
Pavlov. Cond. lever latency0.70.93.5-0.8-0.9-0.4-0.50.6-0.81.20.8-0.6-0.8-1.9-1.1
Pavlov. Cond. magazine entry latency1.11.23.1-0.50.6-0.8-0.0-1.7-1.40.3-1.80.4-1.4-1.0-1.6
Pavlov. Cond. change in total contacts0.20.31.00.10.1-0.10.6-0.20.8-1.0-0.30.30.50.70.5
Pavlov. Cond. index score0.50.72.30.51.30.2-0.3-1.5-0.7-0.1-1.5-0.0-0.90.1-0.7
Pavlov. Cond. latency score0.50.72.20.31.20.0-0.2-1.5-0.7-0.1-1.50.0-0.9-0.0-0.8
Pavlov. Cond. lever contacts0.50.72.10.71.00.10.5-1.00.4-1.1-1.10.70.31.50.6
Pavlov. Cond. magazine entry number0.50.62.00.2-0.80.5-0.11.40.60.21.4-0.40.80.20.8
Pavlov. Cond. intertrial magazine entries0.81.03.11.60.91.8-1.20.6-0.30.80.9-1.00.30.90.9
Pavlov. Cond. lever-magazine prob. diff.0.60.72.70.31.2-0.1-0.1-1.6-0.6-0.3-1.50.2-0.90.0-0.8
Pavlov. Cond. response bias0.50.72.00.60.9-0.00.5-0.90.5-1.1-1.00.80.41.40.6
Time in closed arm before self-admin2.02.26.12.1-0.72.0-1.21.8-0.71.52.5-1.80.40.10.9
Time in closed arm after self-admin0.30.30.70.4-0.50.0-0.2-0.0-0.80.70.3-0.4-0.5-0.8-0.7
Time in open arm before self-admin1.82.06.1-1.02.1-0.4-0.2-2.3-0.7-0.4-2.50.2-1.7-0.8-1.6
Time in open arm after self-admin0.40.41.6-1.2-0.0-0.3-0.50.3-0.00.8-0.2-0.4-0.5-1.3-0.8
Bone: periosteal estimation0.91.93.8-2.0-0.8-1.71.80.31.8-1.7-0.21.71.30.70.8
Bone: periosteal perimeter1.42.46.9-2.6-0.6-2.42.0-0.41.6-1.9-1.12.00.70.1-0.0
Bone: post-yield work0.60.92.8-0.20.5-0.30.9-0.40.9-1.4-0.61.10.91.71.1
Progressive ratio test 1 active lever presses0.70.83.1-1.7-1.0-0.4-0.30.8-0.00.6-0.2-0.6-0.5-1.7-0.7
Progressive ratio test 1 breakpoint0.70.83.4-1.8-1.2-0.4-0.10.90.00.5-0.2-0.5-0.4-1.5-0.6
Progressive ratio test 1 inactive lever presses1.61.74.9-1.6-0.4-0.0-0.9-0.3-1.51.4-1.1-1.1-1.6-2.2-1.8
Progressive ratio test 2 active lever presses0.30.33.3-1.8-0.2-0.3-0.10.50.2-0.1-0.3-0.1-0.0-0.6-0.0
Progressive ratio test 2 breakpoint0.30.43.1-1.8-0.2-0.2-0.30.5-0.00.3-0.3-0.3-0.3-0.9-0.3
Progressive ratio test 2 inactive lever presses0.60.73.0-1.7-0.1-0.3-0.3-0.4-0.50.2-0.9-0.4-0.9-1.3-1.0
Incentive Sensitization - Responses0.60.61.5-1.20.2-0.00.10.81.0-0.60.30.50.90.71.1
Incentive Sensitization - Breakpoint0.50.51.3-1.10.2-0.00.10.71.0-0.60.20.50.80.81.1
Sum of active levers in priming session hrs 5-60.50.51.3-0.70.6-1.10.4-0.80.1-0.4-1.10.8-0.5-0.6-0.7
Progressive ratio0.30.31.1-0.7-0.2-0.70.8-0.20.0-0.6-0.51.10.50.60.4
Food seeking constrained by brief footshock1.31.63.1-0.6-0.6-0.81.40.81.7-1.50.21.41.81.71.7
Seeking ratio, punishment vs. effort0.40.51.90.5-0.20.20.30.71.4-0.60.60.01.00.81.0
Retroperitoneal fat weight1.13.69.6-3.1-1.0-1.72.11.12.3-2.30.32.12.01.31.8
Reaction time number correct1.01.43.70.8-0.50.6-1.40.8-1.01.71.1-1.5-1.0-1.9-1.0
Reaction time mean minus median1.21.63.7-1.1-1.5-1.81.90.11.0-1.5-0.01.81.20.70.6
Reaction time mean minus median AUC1.82.34.3-1.2-2.1-1.62.00.91.3-1.40.61.81.81.21.3
Reaction time num false alarms1.01.44.52.10.72.1-1.30.4-0.91.10.4-1.5-0.10.70.6
Reaction time num false alarms AUC0.81.13.92.00.41.8-1.10.5-0.71.00.4-1.20.10.90.7
Reaction time trials correct on left1.01.43.70.8-0.50.6-1.40.8-1.01.71.1-1.5-1.0-1.9-1.0
Reaction time trials on left0.91.23.30.7-0.60.6-1.30.8-0.81.61.1-1.4-0.9-1.8-0.9
Reaction time mean1.72.45.6-1.4-0.7-2.02.3-0.71.6-2.4-0.72.21.11.20.5
Reaction time mean AUC1.62.15.2-1.1-0.7-1.72.2-0.51.7-2.3-0.42.01.31.30.8
Median of all reaction times1.31.85.1-1.1-0.2-1.61.9-0.81.6-2.3-0.71.80.91.20.5
Reaction time omissions0.81.12.2-0.8-1.0-0.61.30.51.4-1.50.20.91.31.11.1
Reaction time false alarm rate0.71.03.71.60.61.5-0.30.2-0.1-0.00.1-0.50.81.91.3
Reaction time premature initiation rate0.30.41.00.80.31.0-1.00.5-0.21.00.5-0.9-0.1-0.10.1
Reaction time premature initiations0.71.02.70.8-0.10.9-1.40.9-0.51.61.0-1.3-0.5-1.2-0.4
Std. dev. reaction times1.21.73.6-1.0-1.3-1.61.90.21.3-1.6-0.01.81.31.00.8
Reaction time trials completed0.91.23.30.7-0.60.6-1.30.8-0.81.61.1-1.4-0.9-1.8-0.9
Reaction time trials AUC0.91.33.11.0-0.40.8-1.40.7-1.01.70.9-1.5-1.0-1.8-0.9
Run reversals in cocaine runway, females0.80.82.00.7-0.30.9-1.10.6-0.71.40.7-1.3-0.6-1.1-0.6
Run reversals in cocaine runway, males1.31.24.5-0.60.5-1.20.5-1.9-0.6-0.4-2.10.9-1.0-0.5-1.3
Latency to leave start box in cocaine runway0.60.62.5-0.31.6-0.00.3-1.40.1-1.1-1.00.4-0.40.6-0.1
Latency to leave start box in cocaine runway, F0.10.10.3-0.10.60.10.0-0.60.2-0.50.0-0.4-0.5-0.3-0.4
Latency to leave start box in cocaine runway, M0.80.83.00.21.50.30.2-0.90.1-0.8-1.00.80.31.70.9
Std. dev. time between licks in bursts0.30.32.21.50.10.5-0.10.0-0.10.10.30.10.41.00.6
Total sessions with >9 infusions0.50.62.3-1.5-0.8-0.20.10.50.8-0.00.4-0.7-0.2-1.3-0.7
Short access day 1 total inactive lever presses1.61.84.0-1.5-2.0-1.11.31.51.5-0.90.61.21.70.81.3
Short access day 10 total inactive lever presses0.70.82.5-0.9-1.6-1.30.40.2-0.80.9-0.60.5-0.2-1.1-0.9
Short access day 1 total infusions0.80.83.1-0.4-1.70.2-0.01.80.90.21.2-0.50.9-0.20.7
Short access day 10 total infusions0.80.83.0-1.7-0.8-0.91.00.21.5-1.2-0.30.30.4-0.4-0.1
Short access total infusions0.80.93.0-1.3-1.7-0.20.61.41.4-0.40.8-0.40.8-0.40.4
Short access day 1 locomotion1.51.75.3-0.1-2.30.30.22.31.30.22.1-0.71.3-0.11.0
Short access day 10 total locomotion3.54.014.6-3.8-1.2-2.92.5-0.31.5-2.1-1.62.51.00.30.2
Short access total locomotion1.51.67.6-2.8-1.7-1.51.30.71.3-1.0-0.10.50.5-0.8-0.2
One hour access (0.3 mA shock)0.20.30.7-0.80.00.4-0.30.80.8-0.20.4-0.60.3-0.20.4
Compulsive drug intake2.52.510.23.21.02.4-1.90.4-1.31.61.0-1.7-0.40.30.3
One hour access (shock baseline)0.40.52.2-1.50.3-0.60.4-0.31.1-0.9-0.60.40.0-0.2-0.1
Social response proportion1.51.64.4-0.50.4-1.11.7-1.41.2-2.1-1.31.50.61.50.3
Social responses1.21.53.5-0.0-0.2-0.81.5-0.31.5-1.8-0.01.61.41.91.2
Social time0.50.72.0-0.60.2-1.00.8-1.40.1-0.9-1.10.6-0.6-0.4-0.9
Soleus weight0.41.24.3-2.1-1.8-1.11.21.00.9-0.60.70.50.8-0.50.2
Bone: stiffness0.20.30.90.30.5-0.20.1-0.10.1-0.3-0.60.90.40.90.7
Tibialis anterior weight0.72.39.1-2.0-1.0-0.9-0.3-0.0-1.41.4-0.2-0.8-1.6-3.0-2.3
Time to tail flick, vehicle, before self-admin0.70.72.10.9-0.90.50.11.00.6-0.21.4-0.20.90.81.1
Time to tail flick, vehicle, after self-admin0.20.31.2-0.4-0.5-0.6-0.10.2-0.40.5-0.00.0-0.4-1.1-0.7
Time to tail flick, test, before self-admin2.12.07.10.60.60.50.70.61.6-1.50.71.01.82.72.4
Time to tail flick, test, after self-admin0.90.92.4-1.30.8-0.8-0.1-1.0-0.20.0-1.00.1-1.2-1.5-1.5
Delta time to tail flick, vehicle, before/after SA0.60.61.8-1.2-0.3-0.90.1-0.2-0.40.4-0.80.2-0.7-1.4-1.1
Delta time to tail flick, test, before/after SA1.21.04.5-0.70.1-0.7-0.2-0.8-0.40.5-0.4-0.5-1.4-2.1-1.9
Tibia length0.10.20.8-0.70.1-0.50.1-0.2-0.50.1-0.20.1-0.6-0.9-0.7
Ambulatory time before self-admin1.41.42.6-1.4-1.3-1.21.60.71.4-1.40.21.31.40.91.0
Ambulatory time after self-admin1.41.64.1-2.00.3-2.01.4-1.10.4-1.3-1.61.7-0.2-0.3-0.6
Bone: tissue strength1.00.93.5-0.10.1-0.41.2-0.51.7-1.9-0.20.70.81.10.6
Total heroin consumption1.61.97.50.72.70.4-0.9-2.1-1.00.1-2.0-0.2-1.5-0.1-1.1
Bone: trabecular number0.50.83.11.31.81.0-0.9-0.7-0.70.3-0.70.0-0.21.20.5
Bone: trabecular spacing0.91.22.5-1.2-1.4-0.91.31.01.6-1.21.00.71.10.30.8
Bone: trabecular thickness0.20.20.8-0.2-0.10.4-0.30.80.10.40.9-0.60.1-0.40.1
Bone: trabecular tissue density0.70.92.5-0.2-1.10.0-0.70.6-1.31.60.1-0.9-0.7-1.5-1.0
Water consumed over 24 hours0.50.73.01.71.50.7-0.6-0.9-0.3-0.0-0.4-0.1-0.40.70.2
Number of responses in last shaping day0.30.42.3-0.1-1.5-0.50.10.6-0.10.40.4-0.1-0.1-0.9-0.3