Nr2c1

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Brain alternative polyA NM_145780.2 0.05 0.02 5.8e-05 0.05 0.05 0.06 0.05 1.7e-05 1.0e-05 6.6e-06 9.1e-06
2 Adipose isoform ratio XM_008765216.3 0.02 0.01 9.2e-03 0.01 0.01 0 0.01 2.1e-02 2.0e-02 3.4e-01 5.9e-02
3 NAcc alternative polyA NM_145780.2 0.05 0.03 1.2e-04 0.04 0.03 0.03 0.03 7.1e-06 2.1e-04 6.2e-04 1.2e-04
4 NAcc alternative polyA XM_039078458.1 0.05 0.03 8.0e-05 0.05 0.03 0.03 0.03 4.8e-06 1.4e-04 5.1e-04 8.6e-05
5 Adipose alternative polyA NM_145780.2 0.04 0.02 2.2e-04 0.02 0.03 0.02 0.02 1.7e-03 3.4e-04 1.7e-03 1.7e-03
6 Adipose alternative polyA XM_039078458.1 0.04 0.02 3.1e-04 0.02 0.03 0.02 0.02 2.3e-03 4.4e-04 2.7e-03 2.5e-03
7 BLA alternative polyA XM_039078458.1 0.08 0.04 5.3e-05 0.07 0.07 0.07 0.06 1.8e-04 1.1e-04 2.1e-04 4.8e-04
8 Brain alternative polyA XM_039078458.1 0.05 0.02 5.6e-05 0.06 0.05 0.06 0.05 2.8e-06 9.9e-06 5.9e-06 8.3e-06
9 PL alternative polyA NM_145780.2 0.04 0.03 4.4e-05 0.06 0.04 0.05 0.06 3.1e-07 5.8e-05 6.6e-06 9.4e-07
10 PL alternative polyA XM_039078458.1 0.05 0.03 4.1e-05 0.06 0.04 0.05 0.06 2.8e-07 7.0e-05 6.0e-06 7.9e-07
11 BLA alternative polyA NM_145780.2 0.08 0.04 6.0e-05 0.07 0.07 0.07 0.06 1.8e-04 1.1e-04 1.2e-04 3.5e-04
12 BLA isoform ratio NM_145780.2 0.05 0.03 1.9e-03 0.04 0.04 0.03 0.04 2.1e-03 2.2e-03 1.3e-02 3.3e-03
13 Adipose isoform ratio NM_145780.2 0.03 0.02 5.5e-03 0 0.01 0 0 1.0e-01 3.2e-02 1.9e-01 2.5e-01
14 Liver alternative polyA NM_145780.2 0.08 0.03 7.3e-10 0.05 0.07 0.07 0.07 1.9e-06 3.6e-08 1.4e-08 3.5e-08
15 Liver alternative polyA XM_039078458.1 0.08 0.03 2.4e-10 0.05 0.07 0.08 0.07 1.1e-06 1.4e-08 5.8e-09 1.6e-08
16 Liver isoform ratio NM_145780.2 0.09 0.04 5.6e-10 0.08 0.08 0.09 0.08 1.6e-09 5.4e-09 1.0e-09 2.4e-09
17 Liver gene expression Nr2c1 0.03 0.02 2.0e-03 0.02 0.01 0.02 0.01 4.5e-03 1.1e-02 2.5e-03 1.1e-02

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17
Bone: apparent density0.00.10.20.10.3-0.20.2-0.00.0-0.3-0.50.4-0.40.30.50.00.1-0.0-0.10.1
Area under the delay curve0.20.20.60.6-0.00.4-0.40.2-0.20.2-0.40.5-0.5-0.20.80.30.3-0.2-0.3-0.7
BMI with tail1.44.68.62.22.92.4-2.4-2.22.21.8-2.12.2-2.2-1.72.3-2.22.1-2.11.90.7
BMI without tail4.69.514.63.03.83.2-3.2-3.33.33.1-3.12.9-2.9-3.02.9-3.42.8-2.82.92.3
Body weight13.857.979.67.68.98.0-8.0-8.18.17.7-7.27.3-7.3-7.67.6-8.37.3-7.27.05.7
Weight adjusted by age0.10.20.50.40.20.7-0.7-0.0-0.00.7-0.30.2-0.2-0.70.4-0.2-0.10.0-0.0-0.0
Bone surface0.20.40.80.70.80.3-0.3-0.60.60.3-0.60.7-0.7-0.30.9-0.40.8-0.70.40.4
Bone volume0.30.51.10.81.00.5-0.5-0.60.60.4-0.90.9-0.9-0.41.0-0.60.7-0.60.40.4
Breakpoint value in progressive ratio session2.02.23.0-1.4-1.3-1.21.21.7-1.7-1.51.6-1.51.51.5-1.41.7-1.21.3-1.4-1.7
Number of licking bursts0.20.20.40.40.50.1-0.1-0.40.4-0.5-0.50.5-0.50.50.50.30.6-0.50.60.2
Context. condit. distance diff. score0.70.81.71.10.61.0-1.0-0.70.71.3-1.11.0-1.0-1.31.1-0.80.6-0.70.40.3
Locomotion velocity, session 10.80.91.2-0.9-1.1-0.70.71.0-1.0-0.71.1-1.11.10.7-1.10.8-1.01.0-1.0-1.0
Locomotion distance, session 10.00.00.20.1-0.20.2-0.20.1-0.10.10.2-0.20.2-0.1-0.10.20.1-0.0-0.2-0.4
Locomotion velocity, session 20.20.20.5-0.7-0.20.1-0.10.4-0.4-0.20.7-0.70.70.2-0.5-0.2-0.60.5-0.4-0.1
Locomotion distance, session 20.40.50.90.70.91.0-1.0-0.70.70.7-0.60.6-0.6-0.60.7-0.70.7-0.70.60.3
Locomotion velocity, session 30.20.20.4-0.1-0.40.4-0.40.5-0.60.60.4-0.40.4-0.5-0.6-0.3-0.20.2-0.5-0.6
Locomotion distance, session 30.40.41.10.80.51.1-1.1-0.30.31.0-0.50.5-0.5-1.00.4-0.60.6-0.60.4-0.1
Stereotopy head waving bouts, day 30.91.12.2-1.1-1.0-1.51.50.8-0.8-1.40.9-0.90.91.3-1.11.0-0.80.8-0.7-0.5
Stereotopy head waving duration, day 30.30.40.6-0.7-0.6-0.70.70.6-0.6-0.70.6-0.60.60.7-0.70.4-0.50.5-0.6-0.4
Locomotion velocity, session 70.30.31.20.40.31.1-1.1-0.30.30.8-0.20.2-0.2-0.70.2-0.9-0.10.00.1-0.3
Locomotion distance, session 70.10.10.60.30.10.8-0.8-0.10.10.6-0.20.1-0.1-0.50.1-0.5-0.00.0-0.2-0.3
Stereotopy head waving bouts, day 70.10.10.2-0.30.10.2-0.20.1-0.1-0.20.2-0.20.20.2-0.5-0.4-0.50.4-0.2-0.1
Stereotopy head waving duration, day 70.10.20.5-0.4-0.1-0.10.10.4-0.4-0.60.3-0.30.30.6-0.70.0-0.50.5-0.3-0.4
Locomotion velocity, session 80.30.41.10.50.51.0-1.0-0.20.21.0-0.40.4-0.4-1.00.5-0.60.3-0.30.20.5
Locomotion distance, session 83.04.47.02.51.92.5-2.5-1.81.72.6-2.12.1-2.1-2.62.3-1.81.9-1.91.61.0
Degree of sensitization distance0.10.10.2-0.5-0.3-0.20.20.3-0.3-0.50.4-0.40.40.5-0.20.2-0.40.4-0.5-0.2
Degree of sensitization stereotypy0.30.40.8-0.7-0.3-0.20.20.7-0.6-0.70.5-0.50.50.7-0.80.1-0.90.8-0.6-0.7
Conditioned locomotion0.10.10.5-0.10.1-0.10.1-0.50.50.1-0.30.3-0.3-0.10.0-0.7-0.60.5-0.4-0.3
Cocaine response after cond. corrected0.40.41.10.60.80.4-0.4-0.80.80.4-0.80.7-0.7-0.41.0-0.70.5-0.50.40.7
Cocaine response after cond. not corrected0.40.51.00.80.70.4-0.4-0.70.70.6-0.80.8-0.8-0.61.0-0.40.7-0.70.50.8
Cocaine response before conditioning0.10.20.90.2-0.6-0.30.30.6-0.60.10.3-0.30.3-0.1-0.41.00.1-0.10.1-0.0
Saline control response0.70.92.50.71.10.9-0.9-1.11.10.8-0.50.6-0.6-0.80.7-1.60.9-1.01.01.1
Bone: connectivity density0.30.41.1-0.7-0.4-1.11.10.6-0.6-0.90.6-0.60.60.9-0.50.8-0.30.3-0.40.0
Bone: cortical apparent density0.30.41.10.50.61.0-1.0-0.60.61.0-0.50.4-0.4-1.00.3-0.70.2-0.20.50.3
Bone: cortical area2.13.13.81.92.01.3-1.3-1.91.91.8-1.91.9-1.9-1.72.0-1.61.9-1.91.51.3
Bone: cortical porosity0.10.21.2-0.20.60.4-0.4-0.40.40.3-0.00.0-0.0-0.30.0-1.1-0.10.1-0.00.4
Bone: cortical porosity0.30.31.40.10.80.8-0.8-0.70.70.6-0.40.4-0.4-0.60.3-1.20.1-0.10.10.5
Bone: cortical thickness1.32.23.71.21.61.0-1.0-1.71.71.7-1.41.3-1.3-1.71.4-1.91.5-1.41.21.6
Bone: cortical thickness0.40.41.0-1.0-0.3-0.90.90.3-0.2-0.60.7-0.80.80.6-0.70.0-0.60.7-0.6-0.3
Bone: cortical tissue density0.30.41.10.50.51.0-1.0-0.60.61.0-0.40.3-0.3-1.00.2-0.60.2-0.20.40.3
Condit. Reinf. active minus inactive responses2.62.95.0-1.4-1.9-1.81.82.1-2.1-1.51.5-1.61.61.5-1.82.2-1.51.5-1.4-1.4
Condit. Reinf. active-inactive response ratio1.61.83.3-1.0-1.5-1.31.31.7-1.7-1.41.0-1.11.11.4-1.21.8-1.11.1-1.1-1.3
Condit. Reinf. active responses4.15.06.5-2.3-2.4-2.52.52.4-2.4-2.22.2-2.22.22.2-2.52.5-2.02.0-1.8-1.5
Condit. Reinf. inactive responses2.53.04.4-2.1-1.6-1.81.81.5-1.5-1.81.9-1.91.91.8-2.11.5-1.71.7-1.4-0.9
Incentive salience index mean0.70.92.4-0.7-1.1-1.01.01.2-1.2-0.80.8-0.80.80.7-1.11.6-0.70.7-0.6-0.6
Condit. Reinf. lever presses0.00.00.20.10.00.3-0.30.2-0.20.1-0.10.0-0.0-0.1-0.30.5-0.00.10.00.1
Condit. Reinf. active minus inactive responses0.60.71.7-0.8-0.7-0.00.01.3-1.3-0.70.8-0.80.80.7-1.00.8-0.90.9-0.6-0.9
Condit. Reinf. active-inactive response ratio0.10.10.4-0.1-0.00.2-0.20.6-0.6-0.10.1-0.00.00.1-0.20.2-0.10.1-0.1-0.1
Condit. Reinf. active responses0.50.71.4-0.8-0.8-0.10.11.2-1.2-0.70.9-0.90.90.7-1.10.9-0.90.9-0.7-1.0
Condit. Reinf. inactive responses1.31.62.2-1.3-1.4-0.80.81.3-1.3-1.01.4-1.51.51.0-1.41.4-1.41.4-1.2-1.4
Condit. Reinf. lever presses0.20.30.7-0.50.20.7-0.70.4-0.4-0.30.4-0.40.40.3-0.6-0.2-0.80.8-0.4-0.5
Condit. Reinf. lever reinforcers received0.50.61.4-0.6-0.70.0-0.01.2-1.2-0.60.7-0.80.80.6-0.90.9-0.80.8-0.7-1.2
Conditioned reinforcement - actives1.31.32.11.21.01.2-1.2-1.11.10.7-1.41.4-1.4-0.71.2-0.51.1-1.11.01.4
Conditioned reinforcement - inactives0.40.41.70.40.80.3-0.3-0.80.80.2-0.50.7-0.7-0.30.3-0.20.9-0.80.81.3
Conditioned locomotion1.82.23.61.51.41.5-1.5-1.41.41.4-1.51.5-1.5-1.51.4-1.21.6-1.61.41.9
Patch foraging indifference point 0 sec0.00.00.1-0.1-0.1-0.10.1-0.20.2-0.30.10.1-0.10.30.1-0.1-0.20.20.10.1
Patch foraging indifference point AUC0.20.20.90.30.60.0-0.0-0.50.6-0.1-0.40.3-0.30.10.4-0.40.6-0.60.80.9
Delay disc. indifference point, 0s delay0.30.30.7-0.5-0.2-0.40.40.7-0.7-0.80.4-0.20.20.8-0.10.8-0.60.7-0.5-0.8
Delay disc. indifference point, 16s delay0.40.41.21.00.50.9-0.9-0.40.40.3-0.80.7-0.7-0.31.1-0.00.7-0.6-0.0-0.7
Delay disc. indifference point, 2s delay0.50.61.11.10.50.8-0.8-0.40.41.0-0.80.9-0.9-1.00.9-0.30.8-0.70.50.1
Delay disc. indifference point, 24s delay0.90.82.21.50.51.0-1.0-0.40.41.2-1.10.9-0.9-1.21.1-0.21.1-1.00.4-0.0
Delay disc. indifference point, 4s delay0.10.10.30.10.10.3-0.3-0.30.40.2-0.20.4-0.4-0.20.5-0.40.1-0.0-0.20.0
Delay disc. indifference point, 8s delay0.20.21.1-0.1-0.3-0.10.10.6-0.6-0.4-0.00.1-0.10.40.10.5-0.50.5-1.0-1.0
Indifference point function ln k0.00.10.4-0.2-0.2-0.10.10.2-0.20.20.1-0.10.1-0.20.00.3-0.30.3-0.4-0.6
Indifference point function log k0.00.10.4-0.2-0.2-0.10.10.2-0.20.20.1-0.10.1-0.20.00.3-0.30.3-0.4-0.6
Patch foraging total patch changes 0 sec0.00.00.1-0.2-0.1-0.10.1-0.20.3-0.40.1-0.00.00.40.1-0.2-0.30.3-0.00.0
Patch foraging total patch changes 12 sec1.01.32.51.01.30.9-0.9-1.41.40.6-1.01.0-1.0-0.61.2-1.31.1-1.11.51.6
Patch foraging total patch changes 18 sec0.50.72.40.60.70.3-0.3-0.80.90.0-0.60.6-0.6-0.11.1-0.41.0-1.01.51.5
Patch foraging total patch changes 24 sec1.62.03.31.21.41.2-1.2-1.51.51.0-1.21.2-1.2-1.01.5-1.51.6-1.61.81.7
Patch foraging total patch changes 6 sec0.10.10.5-0.2-0.0-0.40.4-0.10.1-0.70.2-0.10.10.70.10.20.0-0.00.30.2
Patch foraging time to switch 0 sec0.10.10.5-0.10.20.7-0.7-0.40.40.2-0.00.1-0.1-0.20.1-0.7-0.10.10.00.3
Patch foraging water rate 0 sec1.42.34.01.91.40.9-0.9-1.51.51.4-1.81.8-1.8-1.42.0-0.71.8-1.71.50.9
Patch foraging water rate 12 sec3.14.87.02.22.51.8-1.8-2.32.41.7-2.72.6-2.6-1.72.2-2.22.0-2.02.11.8
Patch foraging water rate 18 sec0.10.10.30.30.1-0.10.10.1-0.1-0.3-0.30.3-0.30.30.40.20.3-0.30.1-0.5
Patch foraging water rate 24 sec4.76.510.53.12.42.9-2.9-2.32.32.6-3.23.2-3.2-2.62.7-1.72.1-2.11.91.4
Patch foraging water rate 6 sec6.39.212.73.43.23.3-3.3-3.03.02.8-3.63.4-3.4-2.83.4-2.62.7-2.72.71.8
Seeking ratio, delayed vs. immediate footshock0.00.10.1-0.40.3-0.20.2-0.20.2-0.10.3-0.30.30.10.1-0.2-0.20.2-0.20.1
Distance traveled before self-admin0.20.20.60.70.20.5-0.5-0.20.20.6-0.80.6-0.6-0.60.3-0.20.4-0.40.10.0
Distance traveled after self-admin0.30.40.90.90.51.0-1.0-0.40.40.7-0.80.6-0.6-0.70.0-0.40.6-0.60.3-0.4
Extensor digitorum longus weight0.10.51.30.51.20.3-0.3-0.90.90.4-0.70.7-0.7-0.31.0-0.90.7-0.60.30.5
Bone: elastic displacement3.74.25.5-2.3-2.2-1.81.82.2-2.1-1.82.1-2.12.11.8-2.31.7-2.22.2-2.3-1.6
Bone: elastic work1.82.33.3-1.8-1.6-1.61.61.5-1.5-1.11.7-1.71.71.1-1.71.1-1.51.5-1.8-1.0
Bone: endosteal estimation0.20.42.00.3-0.1-0.10.10.2-0.2-1.0-0.30.4-0.41.00.40.8-0.30.4-0.6-1.4
Bone: endosteal perimeter1.53.15.82.31.71.5-1.5-1.81.81.4-2.32.4-2.4-1.42.3-0.81.7-1.71.30.5
Epididymis fat weight2.86.48.62.92.72.9-2.9-2.52.42.6-2.72.7-2.7-2.52.3-2.42.4-2.42.31.3
Delta time in closed arm before/after self-admin0.30.30.80.70.70.1-0.1-0.50.50.5-0.30.5-0.5-0.50.9-0.60.7-0.70.40.3
Delta time in open arm before/after self-admin2.22.23.9-1.9-1.0-1.11.11.5-1.5-1.31.3-1.51.51.3-1.90.8-2.02.0-1.6-1.1
Diff in mean of infusions in LGA sessions1.21.31.9-1.4-1.3-1.21.21.0-1.0-1.01.4-1.41.41.0-1.10.6-1.11.1-1.2-1.2
Delay discount exponential model param0.20.20.8-0.7-0.2-0.60.60.1-0.1-0.40.6-0.60.60.4-0.9-0.0-0.50.40.20.4
Extinction: sum of active levers before priming0.40.40.7-0.4-0.7-0.40.40.8-0.8-0.50.5-0.50.50.5-0.60.8-0.50.5-0.7-0.8
Active lever presses in extinction session 60.10.10.60.30.30.5-0.50.00.00.0-0.30.3-0.30.00.2-0.20.00.0-0.2-0.8
Bone: final force0.60.91.91.11.20.6-0.6-1.01.00.4-1.21.3-1.3-0.41.4-0.81.1-1.00.6-0.0
Bone: final moment0.61.02.01.11.20.7-0.7-1.01.00.5-1.21.3-1.3-0.51.4-0.91.2-1.10.60.1
Food consumed during 24 hour testing period0.40.51.20.50.70.5-0.5-0.70.70.60.00.2-0.2-0.60.8-0.70.9-1.01.10.9
Glucose0.10.10.5-0.20.3-0.70.7-0.40.5-0.0-0.00.2-0.20.00.4-0.30.2-0.20.10.2
Heart weight0.20.40.9-0.1-0.00.8-0.80.9-0.9-0.30.4-0.40.40.3-0.40.5-0.40.5-1.0-0.9
Delay discount hyperbolic model param0.30.30.8-0.8-0.2-0.60.60.2-0.2-0.60.6-0.70.70.6-0.90.1-0.50.40.10.3
Intermittent access intake day 1-15 change0.90.82.30.70.80.3-0.3-1.21.20.5-0.90.8-0.8-0.60.7-0.71.2-1.21.31.5
Intermittent access intake escalation0.90.82.80.70.80.4-0.4-1.11.10.4-1.00.8-0.8-0.40.7-0.51.2-1.21.31.7
Intermittent access intake escalation 20.10.10.50.0-0.1-0.40.4-0.30.30.1-0.30.2-0.2-0.10.0-0.00.4-0.40.40.7
Intermitt. access day 1 inactive lever presses2.42.64.1-2.0-1.4-1.61.61.5-1.5-2.01.8-1.71.71.9-1.81.3-1.61.6-1.5-0.8
Intermitt. access day 15 inactive lever presses1.92.13.0-1.6-1.3-1.51.51.7-1.7-0.81.7-1.71.70.8-1.71.1-1.31.3-1.5-1.2
Intermitt. access escalation Index1.41.22.2-1.0-1.3-1.51.51.2-1.2-0.81.0-1.11.10.8-1.11.0-1.00.9-0.9-0.9
Intermittent access day 1 total infusions3.54.05.52.31.92.3-2.3-1.81.72.2-2.12.2-2.2-2.21.8-1.71.9-1.91.71.4
Intermittent access day 15 total infusions4.85.36.52.52.22.2-2.2-2.42.42.2-2.52.6-2.6-2.32.1-2.02.3-2.32.32.2
Intermittent access terminal intake (last 3 days)4.65.06.42.52.12.1-2.1-2.32.22.4-2.52.5-2.5-2.51.8-2.02.2-2.22.11.9
Intermittent access total infusions4.85.37.32.62.22.4-2.4-2.22.22.4-2.72.6-2.6-2.42.1-1.92.2-2.22.11.8
Intermittent access day 1 locomotion2.32.43.11.61.51.8-1.8-1.61.61.6-1.71.7-1.7-1.61.4-1.71.3-1.31.21.3
Intermittent access day 15 total locomotion3.33.56.61.91.71.7-1.7-1.81.81.9-1.61.8-1.8-1.91.5-1.52.1-2.22.32.6
Intermittent access total locomotion3.33.74.52.01.81.9-1.9-1.91.92.0-2.01.9-1.9-2.01.7-1.82.1-2.12.02.0
Intermittent access standard deviation3.73.96.11.81.71.5-1.5-2.22.21.6-2.11.9-1.9-1.61.8-1.52.5-2.52.32.4
Left kidney weight3.39.415.03.03.53.9-3.9-2.92.93.3-2.72.7-2.7-3.22.8-3.03.0-2.92.62.6
Right kidney weight2.26.19.52.43.03.1-3.1-2.62.52.5-2.22.2-2.2-2.52.2-2.72.4-2.32.11.9
Cocaine induced anxiety2.42.83.8-1.7-1.5-1.51.51.8-1.8-1.31.6-1.61.61.3-1.91.3-1.91.9-1.9-1.9
Post-drug Anxiety1.71.93.2-1.4-1.5-1.11.11.6-1.6-0.81.4-1.41.40.8-1.80.8-1.61.5-1.7-1.5
Baseline Anxiety0.50.51.00.70.30.4-0.4-0.70.70.8-0.50.5-0.5-0.80.6-0.71.0-1.00.81.0
Tail length11.233.843.45.66.45.9-5.9-6.36.36.4-5.55.3-5.3-6.45.4-6.65.2-5.25.45.5
Length with tail15.657.069.27.68.27.9-7.9-7.87.88.3-7.07.0-7.0-8.37.1-8.27.2-7.27.16.7
Length without tail7.215.719.74.04.34.4-4.4-3.93.94.4-3.53.6-3.6-4.43.8-4.23.9-3.93.53.2
Times rat made contact with spout3.84.39.02.22.20.7-0.7-2.02.01.2-2.02.1-2.1-1.22.3-1.03.0-3.02.92.5
Lifetime Intake3.84.36.12.51.82.3-2.3-1.91.82.2-2.42.4-2.4-2.21.9-1.51.9-1.91.71.3
Liver weight, left0.61.01.81.10.91.3-1.3-0.90.91.2-1.01.0-1.0-1.21.0-0.90.6-0.70.30.2
Liver weight, right0.71.13.30.81.31.8-1.8-1.01.01.2-0.70.7-0.7-1.20.8-1.30.6-0.60.80.5
Locomotor activity5.28.310.33.13.23.2-3.2-2.92.93.0-2.62.6-2.6-2.93.0-2.93.0-2.92.61.9
Locomotor testing distance2.33.86.32.22.02.5-2.5-1.81.81.8-1.81.8-1.8-1.82.5-1.52.1-2.11.70.9
Locomotor testing rearing0.61.01.71.10.81.3-1.3-1.01.01.0-0.80.8-0.8-1.01.3-0.71.0-1.00.80.7
Locomotion in novel chamber0.10.20.70.50.00.5-0.5-0.20.20.8-0.40.3-0.3-0.8-0.4-0.20.0-0.00.0-0.2
Locomotion in novel chamber post-restriction0.30.40.80.60.50.6-0.6-0.70.70.5-0.50.5-0.5-0.50.6-0.50.9-0.90.60.6
Fecal boli incidents, locomotor time 10.30.30.80.20.70.7-0.7-0.70.70.4-0.60.6-0.6-0.4-0.0-0.9-0.50.5-0.30.3
Change in fecal boli incidents, locomotor task1.11.12.3-0.6-1.5-1.21.21.4-1.4-0.71.0-0.90.90.7-0.61.4-0.30.3-0.6-1.3
Time >=10cm from walls, locomotor time 11.11.22.2-1.3-0.9-0.80.81.1-1.1-1.01.1-1.01.01.0-0.80.9-1.21.2-1.5-1.2
Bouts of movement, locomotor time 10.80.91.4-0.9-0.5-0.80.80.9-0.8-1.20.8-0.80.81.2-0.80.8-1.11.2-1.0-1.0
Total resting periods, locomotor time 11.21.31.8-1.1-0.8-1.11.11.2-1.1-1.21.0-1.11.11.2-1.11.0-1.31.3-1.2-1.0
Rest time, locomotor task time 12.52.83.7-1.7-1.5-1.71.71.6-1.6-1.51.5-1.61.61.6-1.91.4-1.91.9-1.9-1.4
Distance moved, locomotor task time 11.11.22.60.91.01.2-1.2-1.11.10.9-0.90.7-0.7-0.91.1-0.61.4-1.51.61.2
Vertical activity count, locomotor time 13.84.04.72.11.92.2-2.2-2.12.02.0-1.91.9-1.9-2.02.2-1.62.1-2.12.11.3
Time >=10cm from walls, locomotor time 20.60.71.3-0.8-0.9-0.40.41.1-1.1-0.90.4-0.40.40.9-0.91.2-1.21.2-0.8-0.3
Bouts of movement, locomotor time 20.00.00.20.10.10.1-0.1-0.00.00.5-0.00.1-0.1-0.5-0.3-0.2-0.20.2-0.1-0.3
Total resting periods, locomotor time 20.10.10.5-0.1-0.2-0.20.20.4-0.40.10.2-0.20.2-0.1-0.50.2-0.40.4-0.4-0.7
Rest time, locomotor task time 22.22.53.4-1.5-1.5-1.71.71.8-1.8-1.51.6-1.51.51.5-1.41.8-1.21.2-1.7-1.8
Distance moved, locomotor task time 20.80.91.60.61.01.2-1.2-1.11.10.6-0.90.8-0.8-0.70.7-1.00.6-0.71.11.2
Vertical activity count, locomotor time 26.67.210.52.53.23.0-3.0-3.13.12.3-2.92.8-2.8-2.22.7-3.11.9-2.02.42.3
Light reinforcement 10.10.20.50.50.40.1-0.1-0.10.10.4-0.60.5-0.5-0.40.2-0.00.7-0.70.50.2
Light reinforcement 20.50.71.8-0.8-0.6-1.01.00.7-0.7-1.30.4-0.50.51.3-0.90.8-0.60.6-0.6-0.9
Bone: marrow area0.20.31.90.3-0.0-0.10.10.2-0.2-0.9-0.30.4-0.41.00.40.9-0.30.4-0.6-1.4
Bone: maximum diameter2.03.75.92.42.01.5-1.5-2.02.01.6-2.32.4-2.4-1.62.4-1.32.1-2.01.60.9
Bone: maximum force0.10.20.60.50.60.1-0.1-0.20.20.1-0.50.6-0.6-0.10.7-0.20.7-0.60.1-0.3
Bone: maximum moment0.10.20.50.50.60.2-0.2-0.20.20.1-0.50.5-0.5-0.10.7-0.10.7-0.60.1-0.3
Mean time between licks in bursts0.20.20.80.40.60.9-0.90.0-0.00.8-0.30.2-0.2-0.80.7-0.00.3-0.20.00.1
Mean num. licks in bursts0.20.30.80.50.3-0.30.3-0.40.30.6-0.20.3-0.3-0.60.4-0.30.8-0.80.70.9
Cd content in liver0.60.72.90.91.11.7-1.7-0.30.40.3-0.80.8-0.8-0.30.8-0.50.5-0.40.50.0
Co content in liver3.64.25.02.02.02.0-2.0-2.22.22.2-2.02.0-2.0-2.22.1-2.01.8-1.92.12.0
Cu content in liver1.61.95.21.01.71.4-1.4-2.02.01.0-1.01.1-1.1-0.91.2-2.30.9-0.91.21.1
Fe content in liver0.60.71.30.90.81.0-1.0-0.70.70.8-1.01.1-1.1-0.81.1-0.80.6-0.60.2-0.0
K content in liver0.50.52.0-0.70.4-0.00.0-1.21.20.00.4-0.30.3-0.0-0.3-1.4-0.40.30.51.2
Mg content in liver0.30.30.9-0.9-0.2-0.40.4-0.30.3-0.41.0-0.90.90.5-0.7-0.4-0.60.6-0.00.3
Mn content in liver0.20.21.0-0.00.40.2-0.2-1.01.00.10.00.1-0.1-0.10.2-0.90.1-0.10.60.6
Na content in liver0.10.10.4-0.10.4-0.10.1-0.60.60.1-0.20.4-0.4-0.10.2-0.7-0.20.20.30.4
Rb content in liver0.30.41.2-1.0-0.3-0.60.6-0.10.1-0.70.5-0.50.50.7-0.3-0.4-1.11.0-0.50.2
Se content in liver0.10.20.80.2-0.10.9-0.9-0.10.10.30.2-0.10.1-0.2-0.3-0.4-0.40.3-0.1-0.7
Sr content in liver0.10.10.30.40.30.6-0.6-0.10.10.2-0.30.3-0.3-0.20.2-0.20.5-0.50.20.3
Zn content in liver0.20.30.80.10.50.7-0.7-0.50.50.70.3-0.30.3-0.70.2-0.90.3-0.30.30.6
Bone: minimum diameter3.87.09.93.22.92.3-2.3-2.62.52.5-2.93.1-3.1-2.53.0-2.02.9-2.82.31.6
Time in familiar zone, hab. session 10.20.20.6-0.2-0.30.4-0.40.6-0.6-0.30.5-0.40.40.3-0.60.3-0.50.5-0.4-0.7
Time in novel zone, hab. session 10.40.41.3-0.7-0.6-1.11.10.5-0.5-0.90.4-0.40.40.8-0.20.6-0.40.4-0.4-0.4
Total zone transitions, hab. session 11.92.74.51.91.72.1-2.1-1.21.21.9-1.81.8-1.8-1.91.7-0.91.5-1.41.31.1
Total locomotion distance, hab. session 11.72.45.71.91.42.4-2.4-0.90.81.8-1.51.5-1.5-1.81.4-0.61.5-1.41.10.8
Locomotion velocity, hab. session 12.33.26.32.21.62.5-2.5-1.11.12.2-1.81.8-1.8-2.21.6-0.71.9-1.81.51.2
Time in familiar zone, hab. session 20.00.00.1-0.20.1-0.10.10.2-0.20.00.3-0.30.3-0.0-0.2-0.20.0-0.0-0.0-0.2
Time in novel zone, hab. session 20.60.61.3-0.5-0.8-0.30.31.0-1.0-0.90.5-0.50.50.9-0.61.1-0.70.8-0.9-0.9
Total zone transitions, hab. session 20.20.31.40.60.21.2-1.20.2-0.20.5-0.20.2-0.2-0.50.10.50.3-0.2-0.0-0.3
Total locomotion distance, hab. session 20.20.20.90.60.10.9-0.90.2-0.30.3-0.30.2-0.2-0.30.20.80.4-0.3-0.0-0.2
Locomotion velocity, hab. session 20.20.21.10.70.11.0-1.00.1-0.20.5-0.30.3-0.3-0.50.20.80.3-0.2-0.0-0.2
Novel to familiar place preference ratio0.20.20.9-0.2-0.10.9-0.90.3-0.30.40.3-0.30.3-0.4-0.6-0.1-0.40.30.20.5
Novelty place preference0.30.30.8-0.5-0.30.8-0.80.6-0.60.20.6-0.60.6-0.2-0.90.2-0.60.6-0.10.3
Time in novel zone, NPP test0.20.20.8-0.4-0.20.9-0.90.5-0.50.20.5-0.50.5-0.2-0.7-0.0-0.50.5-0.00.3
Total zone transitions, NPP test0.60.82.10.90.91.4-1.4-0.70.71.2-0.70.6-0.6-1.20.9-0.60.8-0.80.40.3
Total locomotion distance, NPP test0.50.61.11.00.71.0-1.0-0.60.61.0-0.60.6-0.6-1.00.8-0.31.0-1.00.60.5
Locomotion velocity, NPP test0.20.30.70.70.40.7-0.7-0.40.40.8-0.40.4-0.4-0.80.5-0.00.7-0.70.40.4
Intraocular pressure1.01.33.4-0.9-1.3-1.81.81.3-1.3-1.40.9-1.01.01.4-0.51.8-0.20.2-0.3-0.6
Delta distance traveled before/after self-admin0.10.10.30.30.50.4-0.4-0.50.50.1-0.20.2-0.2-0.1-0.0-0.50.4-0.40.4-0.0
Delta ambulatory time before/after self-admin0.20.20.6-0.5-0.3-0.30.30.3-0.2-0.70.4-0.40.40.7-0.50.2-0.40.5-0.5-0.8
Parametrial fat weight0.50.93.2-0.8-0.7-0.70.70.7-0.7-0.80.7-0.60.60.9-0.70.5-1.41.4-1.3-1.8
Pavlov. Cond. lever latency0.40.51.10.80.71.0-1.0-0.50.50.7-0.70.8-0.8-0.71.0-0.60.4-0.40.2-0.2
Pavlov. Cond. magazine entry latency0.60.82.5-0.6-0.8-0.80.81.2-1.2-0.80.7-0.70.70.8-0.91.6-0.70.7-0.5-0.8
Pavlov. Cond. change in total contacts0.20.30.9-0.2-0.4-0.90.90.3-0.3-0.80.2-0.20.20.8-0.40.8-0.10.10.2-0.1
Pavlov. Cond. index score0.50.71.4-0.7-0.7-1.01.00.9-0.9-0.80.8-0.80.80.8-1.01.2-0.60.6-0.4-0.5
Pavlov. Cond. latency score0.50.61.2-0.7-0.7-1.01.00.8-0.8-0.80.8-0.80.80.8-0.91.1-0.40.5-0.3-0.3
Pavlov. Cond. lever contacts0.10.10.3-0.1-0.0-0.30.3-0.10.10.00.2-0.20.2-0.0-0.40.00.1-0.10.30.6
Pavlov. Cond. magazine entry number0.40.51.30.40.70.7-0.7-0.80.80.6-0.50.5-0.5-0.60.7-1.10.6-0.60.40.8
Pavlov. Cond. intertrial magazine entries0.10.10.60.1-0.1-0.50.5-0.10.1-0.1-0.30.3-0.30.10.1-0.1-0.30.3-0.5-0.8
Pavlov. Cond. lever-magazine prob. diff.0.40.51.1-0.6-0.6-0.70.70.8-0.8-0.70.6-0.70.70.7-0.81.1-0.50.5-0.3-0.5
Pavlov. Cond. response bias0.10.20.5-0.3-0.4-0.60.60.4-0.4-0.40.3-0.30.30.4-0.60.7-0.30.30.0-0.1
Pavlov. Cond. lever latency0.20.20.70.10.2-0.40.4-0.70.70.2-0.10.2-0.2-0.20.4-0.40.6-0.60.40.8
Pavlov. Cond. magazine entry latency0.30.40.70.80.3-0.00.0-0.30.30.8-0.80.7-0.7-0.80.7-0.10.7-0.70.70.6
Pavlov. Cond. change in total contacts1.52.04.31.71.42.1-2.1-1.01.01.7-1.51.4-1.4-1.71.5-0.91.1-1.11.20.5
Pavlov. Cond. index score0.50.61.11.10.70.8-0.8-0.50.51.0-1.11.0-1.0-0.90.9-0.40.5-0.50.70.3
Pavlov. Cond. latency score0.20.30.60.80.40.6-0.6-0.30.30.7-0.70.7-0.7-0.70.6-0.20.2-0.30.50.2
Pavlov. Cond. lever contacts0.10.20.70.40.40.8-0.80.2-0.2-0.1-0.50.4-0.40.10.10.0-0.30.3-0.1-0.8
Pavlov. Cond. magazine entry number0.50.71.4-1.2-0.6-0.40.40.6-0.6-0.91.1-1.01.00.9-1.00.1-0.80.8-1.0-0.3
Pavlov. Cond. intertrial magazine entries0.10.20.4-0.5-0.10.1-0.10.3-0.3-0.00.5-0.60.60.0-0.7-0.2-0.40.4-0.5-0.1
Pavlov. Cond. lever-magazine prob. diff.0.70.91.51.20.90.9-0.9-0.70.71.1-1.21.2-1.2-1.11.1-0.50.7-0.70.90.6
Pavlov. Cond. response bias0.30.41.00.90.71.0-1.0-0.20.20.5-0.90.8-0.8-0.50.6-0.30.3-0.30.4-0.2
Time in closed arm before self-admin0.30.30.90.50.30.7-0.7-0.00.00.7-0.20.1-0.1-0.70.10.11.0-0.90.80.6
Time in closed arm after self-admin0.60.61.31.10.81.1-1.1-0.40.40.6-0.90.9-0.9-0.60.9-0.50.5-0.50.3-0.0
Time in open arm before self-admin0.00.10.20.1-0.4-0.40.4-0.00.0-0.30.10.1-0.10.30.30.3-0.10.1-0.1-0.1
Time in open arm after self-admin1.31.42.1-1.5-1.0-1.21.21.2-1.2-1.01.1-1.41.41.0-1.40.8-1.51.4-1.1-0.8
Bone: periosteal estimation0.51.12.11.41.10.8-0.8-1.01.00.7-1.41.5-1.5-0.71.5-0.51.0-0.90.5-0.1
Bone: periosteal perimeter1.32.13.31.81.51.4-1.4-1.41.41.3-1.81.8-1.8-1.31.8-0.91.4-1.40.90.5
Bone: post-yield work0.10.20.60.50.4-0.30.3-0.10.1-0.1-0.50.6-0.60.10.7-0.10.8-0.80.4-0.1
Progressive ratio test 1 active lever presses11.812.315.03.73.53.7-3.7-3.83.83.2-3.93.8-3.8-3.23.5-3.43.4-3.43.12.8
Progressive ratio test 1 breakpoint10.811.313.73.63.33.5-3.5-3.53.53.1-3.73.7-3.7-3.13.3-3.23.2-3.32.92.6
Progressive ratio test 1 inactive lever presses0.20.20.40.50.60.5-0.5-0.50.50.4-0.60.5-0.5-0.50.2-0.40.5-0.50.40.4
Progressive ratio test 2 active lever presses4.44.85.52.32.02.2-2.2-2.22.22.2-2.32.3-2.3-2.22.0-2.02.2-2.22.12.0
Progressive ratio test 2 breakpoint5.35.96.72.52.32.2-2.2-2.52.52.4-2.52.6-2.6-2.42.5-2.22.5-2.62.52.3
Progressive ratio test 2 inactive lever presses0.50.50.90.80.70.6-0.6-0.70.60.8-0.80.9-0.9-0.80.6-0.70.8-0.80.60.7
Incentive Sensitization - Responses2.72.84.61.51.61.3-1.3-1.81.81.6-1.41.6-1.6-1.71.6-1.51.8-1.92.02.1
Incentive Sensitization - Breakpoint2.32.34.31.31.51.2-1.2-1.71.71.5-1.21.4-1.4-1.51.4-1.41.7-1.71.92.1
Sum of active levers in priming session hrs 5-60.10.10.20.30.40.4-0.40.0-0.0-0.1-0.20.3-0.30.10.40.30.4-0.30.40.1
Progressive ratio1.92.24.7-1.2-2.2-1.41.41.8-1.8-0.91.5-1.61.60.9-1.42.1-1.11.1-1.3-1.4
Food seeking constrained by brief footshock1.92.33.71.31.51.2-1.2-1.91.91.5-1.41.3-1.3-1.51.0-1.91.6-1.71.61.8
Seeking ratio, punishment vs. effort2.22.65.41.32.21.4-1.4-2.12.11.2-1.61.5-1.5-1.21.2-2.31.4-1.41.51.7
Retroperitoneal fat weight2.17.010.63.02.73.2-3.2-2.52.43.2-2.42.4-2.4-3.22.4-2.22.7-2.62.51.5
Reaction time number correct0.10.10.30.3-0.0-0.10.10.2-0.2-0.2-0.40.4-0.40.20.20.3-0.0-0.0-0.1-0.5
Reaction time mean minus median1.31.73.1-1.4-1.3-1.11.11.4-1.5-1.01.7-1.61.61.0-1.71.3-1.01.0-1.0-0.7
Reaction time mean minus median AUC1.41.83.3-1.4-1.3-1.41.41.4-1.5-1.01.8-1.71.71.0-1.71.3-0.90.9-0.9-0.4
Reaction time num false alarms0.60.91.7-1.3-0.8-0.90.90.5-0.5-1.21.1-1.01.01.2-0.90.2-1.11.0-0.9-0.5
Reaction time num false alarms AUC1.11.52.4-1.6-1.1-1.01.00.9-0.9-1.51.3-1.21.21.5-1.30.6-1.51.4-1.4-0.9
Reaction time trials correct on left0.10.10.30.3-0.0-0.10.10.2-0.2-0.2-0.40.4-0.40.20.20.3-0.0-0.0-0.1-0.5
Reaction time trials on left0.10.10.40.3-0.1-0.20.20.3-0.3-0.3-0.30.4-0.40.30.20.3-0.10.1-0.2-0.6
Reaction time mean0.00.00.2-0.0-0.2-0.20.20.1-0.2-0.10.4-0.30.30.1-0.10.40.3-0.20.0-0.2
Reaction time mean AUC0.00.00.20.20.1-0.00.0-0.10.10.10.2-0.10.1-0.10.10.10.5-0.50.30.1
Median of all reaction times0.20.30.80.70.50.5-0.5-0.50.50.4-0.40.5-0.5-0.40.7-0.20.9-0.90.60.0
Reaction time omissions2.83.84.9-1.8-2.2-1.21.22.2-2.2-2.11.7-1.71.72.1-2.22.2-1.91.9-2.0-2.2
Reaction time false alarm rate0.91.22.4-1.5-1.0-0.90.90.7-0.7-1.31.3-1.31.31.3-1.30.5-1.31.3-1.1-0.6
Reaction time premature initiation rate0.10.20.80.20.10.5-0.50.3-0.3-0.5-0.20.2-0.20.50.30.9-0.10.2-0.2-0.5
Reaction time premature initiations0.10.20.40.50.30.5-0.50.1-0.1-0.3-0.50.5-0.50.30.60.70.2-0.20.1-0.3
Std. dev. reaction times1.21.72.9-1.4-1.3-1.11.11.4-1.4-1.11.7-1.61.61.1-1.71.3-1.01.0-1.2-0.9
Reaction time trials completed0.10.10.40.3-0.1-0.20.20.3-0.3-0.3-0.30.4-0.40.30.20.3-0.10.1-0.2-0.6
Reaction time trials AUC0.10.10.30.40.0-0.10.10.1-0.1-0.3-0.50.5-0.50.30.30.20.0-0.0-0.1-0.6
Run reversals in cocaine runway, females1.01.01.41.20.81.0-1.0-1.01.01.2-1.01.0-1.0-1.21.0-0.91.1-1.00.60.4
Run reversals in cocaine runway, males0.10.10.2-0.3-0.2-0.30.30.3-0.3-0.20.5-0.50.50.2-0.4-0.1-0.20.1-0.1-0.1
Latency to leave start box in cocaine runway0.10.10.50.40.40.1-0.1-0.10.00.5-0.10.2-0.2-0.50.7-0.20.5-0.50.30.0
Latency to leave start box in cocaine runway, F0.40.50.8-0.7-0.8-0.80.80.8-0.8-0.60.9-0.90.90.6-0.20.8-0.30.3-0.5-0.6
Latency to leave start box in cocaine runway, M3.02.94.11.72.01.3-1.3-1.61.62.0-1.51.5-1.5-2.01.6-2.01.9-1.91.81.6
Std. dev. time between licks in bursts1.11.32.4-1.0-1.00.7-0.71.5-1.5-0.31.2-1.31.30.3-1.01.2-1.31.4-1.6-1.3
Total sessions with >9 infusions3.03.35.22.21.62.0-2.0-1.81.81.9-2.32.1-2.1-1.91.6-1.71.6-1.61.40.9
Short access day 1 total inactive lever presses0.00.00.10.1-0.1-0.20.20.1-0.1-0.1-0.20.2-0.20.00.10.10.0-0.0-0.3-0.1
Short access day 10 total inactive lever presses5.05.68.3-2.7-2.2-2.62.62.6-2.6-1.22.9-2.82.81.2-2.61.4-2.32.3-2.6-1.8
Short access day 1 total infusions2.32.53.82.01.31.4-1.4-1.51.51.9-1.91.8-1.8-1.91.6-1.31.4-1.41.20.7
Short access day 10 total infusions5.25.88.32.62.62.9-2.9-2.52.52.5-2.72.7-2.7-2.52.1-2.21.9-2.02.01.6
Short access total infusions4.45.06.92.62.22.5-2.5-2.12.12.5-2.62.6-2.6-2.52.2-1.81.9-1.91.71.2
Short access day 1 locomotion3.43.74.92.02.11.6-1.6-2.22.22.0-2.12.1-2.1-2.01.7-2.21.7-1.71.61.6
Short access day 10 total locomotion0.20.20.50.20.30.6-0.6-0.70.70.2-0.50.3-0.3-0.20.1-0.50.4-0.30.20.6
Short access total locomotion3.23.34.81.71.91.9-1.9-2.22.21.5-2.01.8-1.8-1.51.5-1.91.8-1.71.71.9
One hour access (0.3 mA shock)3.03.55.42.11.31.7-1.7-1.61.62.1-1.91.9-1.9-2.11.5-0.92.3-2.32.12.1
Compulsive drug intake2.62.63.6-1.8-1.7-1.91.91.7-1.7-1.01.9-1.91.91.1-1.61.6-1.41.4-1.6-1.1
One hour access (shock baseline)5.15.97.62.82.12.5-2.5-2.32.32.4-2.72.5-2.5-2.52.1-1.82.6-2.62.52.4
Social response proportion1.92.14.11.71.81.7-1.7-1.41.41.5-1.51.6-1.6-1.51.3-2.00.9-0.90.50.0
Social responses1.21.52.51.51.21.6-1.6-1.01.01.6-1.21.3-1.3-1.51.1-1.30.9-0.90.50.2
Social time1.21.62.61.41.40.8-0.8-1.31.30.6-1.41.4-1.4-0.61.6-1.51.6-1.61.10.9
Soleus weight0.10.20.60.50.80.3-0.3-0.60.60.1-0.60.6-0.6-0.00.6-0.50.5-0.50.1-0.3
Bone: stiffness1.72.74.81.72.21.8-1.8-1.71.71.0-1.71.8-1.8-1.01.9-1.71.6-1.51.40.3
Tibialis anterior weight0.10.41.1-0.7-0.3-0.70.70.4-0.4-1.00.6-0.60.61.1-0.20.6-0.40.5-0.9-0.9
Time to tail flick, vehicle, before self-admin3.94.07.72.11.91.4-1.4-1.81.81.8-1.92.0-2.0-1.82.0-0.92.4-2.42.72.8
Time to tail flick, vehicle, after self-admin1.71.83.6-1.4-1.1-0.80.81.3-1.3-1.61.2-1.11.11.6-0.90.9-1.91.9-1.7-1.4
Time to tail flick, test, before self-admin0.20.20.60.30.30.4-0.4-0.80.80.3-0.20.4-0.4-0.30.4-0.80.5-0.50.50.0
Time to tail flick, test, after self-admin0.10.10.20.2-0.2-0.40.40.0-0.00.1-0.10.3-0.3-0.10.50.10.3-0.30.40.0
Delta time to tail flick, vehicle, before/after SA5.05.08.0-2.5-2.0-1.71.72.1-2.1-2.32.2-2.22.22.3-1.91.3-2.72.7-2.8-2.7
Delta time to tail flick, test, before/after SA0.30.30.7-0.3-0.4-0.80.80.8-0.8-0.20.4-0.40.40.2-0.10.7-0.30.3-0.20.1
Tibia length10.830.536.86.15.75.7-5.7-5.55.46.1-5.45.5-5.5-6.05.4-5.15.5-5.55.34.5
Ambulatory time before self-admin0.40.51.00.80.51.0-1.0-0.60.60.7-0.90.8-0.8-0.70.3-0.60.4-0.40.20.3
Ambulatory time after self-admin0.50.61.51.00.61.2-1.2-0.60.61.0-0.90.8-0.8-1.00.0-0.60.5-0.50.2-0.3
Bone: tissue strength0.50.50.90.50.90.7-0.7-0.90.90.3-0.50.5-0.5-0.30.8-1.00.8-0.80.70.5
Total heroin consumption0.60.71.4-0.7-0.9-0.70.71.0-1.0-0.60.8-0.80.80.6-0.61.1-0.70.8-0.9-1.2
Bone: trabecular number0.30.51.6-0.6-0.6-1.31.30.6-0.6-1.00.3-0.40.41.0-0.20.9-0.30.4-0.4-0.3
Bone: trabecular spacing0.20.20.5-0.4-0.7-0.40.40.6-0.70.30.6-0.60.6-0.3-0.60.5-0.20.2-0.40.1
Bone: trabecular thickness0.40.41.20.71.00.8-0.8-0.70.70.5-0.80.7-0.7-0.50.6-1.10.3-0.30.30.4
Bone: trabecular tissue density0.00.00.1-0.0-0.00.1-0.1-0.30.30.1-0.10.1-0.1-0.10.0-0.3-0.30.30.0-0.4
Water consumed over 24 hours1.21.42.51.11.51.2-1.2-1.41.40.4-1.01.1-1.1-0.51.2-1.21.3-1.31.61.4
Number of responses in last shaping day1.31.42.31.40.90.9-0.9-1.21.11.3-1.01.1-1.1-1.31.2-1.21.4-1.51.31.0