Hub : Genes

Lamtor3

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R² and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

#	Tissue	Modality	RNA phenotype	h2	h2 SE	h2 P	xQTL R2	BLUP R2	ENET R2	LASSO R2	xQTL P	BLUP P	ENET P	LASSO P
1	Adipose	mRNA stability	Lamtor3	0.06	0.03	5.5e-06	0.01	0.03	0.04	0.03	1.8e-02	1.9e-04	6.9e-05	2.6e-04
2	Liver	alternative TSS	NM_001008375.1	0.04	0.03	2.0e-03	0	0	0.01	0.01	1.8e-01	9.9e-02	2.6e-02	2.4e-02
3	Liver	alternative TSS	XM_006233385.4	0.04	0.03	2.4e-03	0	0	0.01	0.01	1.4e-01	8.0e-02	1.7e-02	1.3e-02
4	LHb	mRNA stability	Lamtor3	0.19	0.1	8.8e-03	0.02	0	0	0.01	9.4e-02	2.4e-01	3.0e-01	1.8e-01
5	Liver	gene expression	Lamtor3	0.07	0.05	6.2e-04	0.01	0.03	0	0.01	4.2e-02	7.7e-04	2.9e-01	1.4e-02
6	NAcc	isoform ratio	NM_001008375.1	0.03	0.02	9.4e-03	-0	0.01	0.01	-0	3.8e-01	1.1e-02	1.4e-02	3.8e-01

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6
Bone: apparent density	0.8	1.3	2.3	-1.1	1.5	-1.5	0.8	-0.1	1.1
Area under the delay curve	0.1	0.1	0.2	-0.0	-0.5	0.5	-0.0	-0.3	-0.3
BMI with tail	2.8	8.9	17.9	4.2	-4.0	4.0	1.2	1.2	1.2
BMI without tail	2.7	5.6	15.4	3.9	-2.9	2.9	-0.7	0.8	-0.1
Body weight	2.5	10.6	27.9	5.3	-3.9	3.8	1.2	2.1	0.5
Weight adjusted by age	0.3	0.4	0.7	0.4	-0.7	0.6	-0.8	0.2	-0.7
Bone surface	0.1	0.2	0.5	0.6	-0.0	0.0	0.6	-0.1	0.7
Bone volume	0.1	0.2	0.4	0.3	0.5	-0.5	0.6	0.1	0.3
Breakpoint value in progressive ratio session	1.2	1.3	3.7	-0.6	0.1	-0.1	1.8	0.5	1.9
Number of licking bursts	0.8	1.0	3.4	1.0	-0.3	0.3	1.9	-0.3	1.0
Context. condit. distance diff. score	0.5	0.6	1.2	-0.6	0.4	-0.4	0.9	-0.9	1.1
Locomotion velocity, session 1	0.9	1.0	1.7	1.3	-0.7	0.6	0.8	1.2	-1.2
Locomotion distance, session 1	0.7	0.9	2.3	1.5	-0.9	0.8	0.7	0.8	-0.8
Locomotion velocity, session 2	0.2	0.3	1.0	-0.0	-0.3	0.2	1.0	0.7	-0.0
Locomotion distance, session 2	0.9	1.3	3.8	1.0	-1.1	1.0	0.1	0.9	-1.9
Locomotion velocity, session 3	0.9	1.1	3.0	1.7	-0.8	0.7	1.2	0.0	-1.1
Locomotion distance, session 3	0.3	0.3	0.5	0.7	-0.5	0.5	0.7	-0.6	0.0
Stereotopy head waving bouts, day 3	0.7	0.8	1.6	0.9	-1.0	1.0	-0.6	0.4	-1.3
Stereotopy head waving duration, day 3	0.9	1.1	2.6	1.6	-1.2	1.2	0.2	0.5	-0.7
Locomotion velocity, session 7	0.6	0.7	2.4	0.7	-0.6	0.6	1.5	0.8	-0.0
Locomotion distance, session 7	1.2	1.5	2.8	1.0	-1.5	1.4	1.7	-0.3	1.0
Stereotopy head waving bouts, day 7	1.2	1.4	4.6	-0.3	0.6	-0.5	-1.7	0.2	-2.1
Stereotopy head waving duration, day 7	1.5	1.8	7.6	-0.1	0.3	-0.3	-1.8	0.1	-2.8
Locomotion velocity, session 8	0.1	0.1	0.2	0.3	-0.1	0.1	0.4	0.2	-0.3
Locomotion distance, session 8	0.4	0.6	2.4	0.7	-0.6	0.5	1.5	0.4	-0.2
Degree of sensitization distance	0.6	0.7	2.1	0.0	-0.5	0.4	1.2	0.2	1.4
Degree of sensitization stereotypy	1.3	1.4	4.5	-0.7	0.8	-0.7	-1.5	0.6	-2.1
Conditioned locomotion	0.8	1.0	1.5	-0.6	1.2	-1.2	-1.0	0.6	-1.1
Cocaine response after cond. corrected	0.4	0.4	0.9	-0.6	0.7	-0.7	0.6	0.9	-0.1
Cocaine response after cond. not corrected	0.6	0.7	1.4	-0.9	0.8	-0.8	0.6	1.2	0.3
Cocaine response before conditioning	0.2	0.2	0.5	0.5	-0.7	0.7	-0.2	0.2	0.3
Saline control response	1.8	2.4	6.1	1.4	-1.4	1.4	-1.3	-0.6	-2.5
Bone: connectivity density	1.4	2.2	3.9	-1.4	2.0	-2.0	0.7	-0.8	1.5
Bone: cortical apparent density	0.0	0.0	0.2	-0.4	0.0	-0.0	0.2	0.1	-0.2
Bone: cortical area	1.9	2.9	6.1	2.5	-2.1	2.1	1.3	0.6	0.8
Bone: cortical porosity	0.5	0.6	1.8	1.4	-0.3	0.2	0.2	0.7	-1.0
Bone: cortical porosity	0.8	0.9	2.2	1.5	-0.7	0.7	0.6	1.0	-0.8
Bone: cortical thickness	1.0	1.6	3.3	1.5	-0.9	0.9	1.8	1.0	1.3
Bone: cortical thickness	0.7	0.9	3.3	0.5	-0.2	0.2	1.1	1.8	0.6
Bone: cortical tissue density	0.0	0.0	0.2	-0.4	0.0	-0.0	0.2	0.1	-0.1
Condit. Reinf. active minus inactive responses	1.2	1.4	2.6	1.5	-1.6	1.6	0.5	0.5	-0.6
Condit. Reinf. active-inactive response ratio	2.7	2.9	4.7	1.8	-2.2	2.1	1.9	1.0	-0.1
Condit. Reinf. active responses	0.5	0.6	1.3	0.6	-0.8	0.8	-0.5	0.4	-1.1
Condit. Reinf. inactive responses	1.1	1.4	4.7	-0.8	0.9	-0.9	-2.2	-0.1	-1.1
Incentive salience index mean	0.8	1.0	1.9	1.3	-1.4	1.3	0.5	0.5	-0.1
Condit. Reinf. lever presses	0.1	0.2	0.4	0.6	-0.3	0.3	-0.6	-0.2	-0.2
Condit. Reinf. active minus inactive responses	0.3	0.3	0.6	0.8	-0.7	0.8	-0.2	-0.1	0.5
Condit. Reinf. active-inactive response ratio	0.3	0.3	1.2	-0.0	-0.0	0.0	0.9	-0.1	1.1
Condit. Reinf. active responses	0.8	1.1	2.2	1.4	-1.5	1.5	-0.3	0.4	0.6
Condit. Reinf. inactive responses	1.8	2.2	4.7	2.2	-2.0	2.0	-0.6	0.4	-0.2
Condit. Reinf. lever presses	0.4	0.5	0.9	0.9	-0.6	0.6	-0.3	0.6	0.9
Condit. Reinf. lever reinforcers received	0.5	0.7	1.1	1.0	-1.0	1.1	-0.4	0.5	0.6
Conditioned reinforcement - actives	1.2	1.2	3.1	0.6	-0.3	0.4	-1.5	-1.2	-1.8
Conditioned reinforcement - inactives	1.2	1.3	3.9	-0.8	0.1	-0.0	-2.0	-0.6	-1.8
Conditioned locomotion	0.9	1.1	5.1	0.5	0.5	-0.5	-0.8	-2.3	-0.4
Patch foraging indifference point 0 sec	0.3	0.5	2.3	-0.3	0.5	-0.5	-0.1	-1.5	0.6
Patch foraging indifference point AUC	0.9	1.0	2.6	1.2	-0.9	0.9	1.6	-0.0	0.8
Delay disc. indifference point, 0s delay	0.7	0.7	3.9	0.2	0.3	-0.3	-0.5	-2.0	-0.2
Delay disc. indifference point, 16s delay	0.4	0.4	0.8	0.9	-0.7	0.7	0.3	-0.3	0.3
Delay disc. indifference point, 2s delay	0.8	0.9	2.2	-0.6	0.6	-0.6	-1.2	-1.5	-0.8
Delay disc. indifference point, 24s delay	0.3	0.3	0.9	-1.0	0.3	-0.3	-0.9	-0.3	0.0
Delay disc. indifference point, 4s delay	0.1	0.1	0.6	-0.8	-0.0	0.0	0.2	0.1	0.3
Delay disc. indifference point, 8s delay	0.6	0.6	1.5	0.7	-0.9	0.9	0.0	0.4	-1.2
Indifference point function ln k	0.2	0.2	0.3	0.6	-0.6	0.5	-0.2	0.3	-0.3
Indifference point function log k	0.2	0.2	0.3	0.6	-0.6	0.5	-0.2	0.3	-0.3
Patch foraging total patch changes 0 sec	0.3	0.4	1.9	0.1	0.3	-0.3	-0.1	-1.4	0.7
Patch foraging total patch changes 12 sec	0.3	0.4	1.0	0.4	-0.6	0.7	0.7	-0.4	1.0
Patch foraging total patch changes 18 sec	0.3	0.4	1.6	-0.0	0.1	-0.1	0.4	-1.3	0.8
Patch foraging total patch changes 24 sec	0.5	0.6	1.2	1.1	-0.7	0.7	-0.7	-0.9	-0.6
Patch foraging total patch changes 6 sec	1.1	1.7	6.4	-0.1	-0.2	0.2	1.6	-1.1	2.5
Patch foraging time to switch 0 sec	1.2	1.9	4.5	-1.8	1.1	-1.0	-2.1	-0.6	-0.9
Patch foraging water rate 0 sec	0.8	1.3	3.3	1.2	0.4	-0.5	1.8	0.7	1.4
Patch foraging water rate 12 sec	1.2	1.8	3.1	1.6	-1.8	1.7	0.8	1.2	-0.0
Patch foraging water rate 18 sec	1.3	1.7	3.6	1.1	-0.9	0.8	1.9	0.8	1.9
Patch foraging water rate 24 sec	1.0	1.4	3.5	1.4	-0.8	0.7	1.9	0.5	1.3
Patch foraging water rate 6 sec	2.9	4.3	7.8	1.6	-2.0	1.9	2.8	2.7	0.7
Seeking ratio, delayed vs. immediate footshock	1.6	1.8	3.6	-1.7	1.9	-1.9	-0.9	-0.4	0.3
Distance traveled before self-admin	0.6	0.6	3.6	0.3	-0.1	0.2	-1.9	-0.2	-0.3
Distance traveled after self-admin	0.2	0.2	0.5	-0.5	-0.1	0.2	-0.7	-0.6	0.5
Extensor digitorum longus weight	2.6	10.2	19.6	4.4	-3.5	3.5	0.8	3.8	-1.3
Bone: elastic displacement	0.5	0.6	2.4	1.6	-0.4	0.3	0.6	0.7	0.3
Bone: elastic work	1.1	1.5	2.8	1.4	-0.4	0.3	1.6	1.7	1.1
Bone: endosteal estimation	0.7	1.5	3.1	1.8	-1.6	1.7	-0.6	-0.3	-0.4
Bone: endosteal perimeter	1.0	2.1	4.2	2.1	-1.9	1.9	-0.9	-0.5	-0.8
Epididymis fat weight	1.5	3.4	6.8	2.5	-2.6	2.6	-0.5	-0.5	-0.8
Delta time in closed arm before/after self-admin	1.2	1.2	3.5	0.9	-0.8	0.9	-1.1	-0.5	-1.9
Delta time in open arm before/after self-admin	1.0	0.9	2.1	0.6	-1.1	1.1	-0.7	-0.0	-1.4
Diff in mean of infusions in LGA sessions	1.2	1.3	3.3	-1.1	-0.3	0.3	1.7	0.3	1.8
Delay discount exponential model param	0.1	0.1	0.2	0.3	0.4	-0.4	0.0	0.1	0.3
Extinction: sum of active levers before priming	1.5	1.5	2.8	-0.5	-0.9	0.9	1.6	1.7	1.3
Active lever presses in extinction session 6	0.7	0.7	1.5	-0.8	0.5	-0.6	1.2	-0.7	0.8
Bone: final force	0.3	0.5	0.8	0.7	-0.7	0.8	0.9	-0.0	0.5
Bone: final moment	0.3	0.6	1.4	0.7	-0.7	0.7	1.2	0.1	0.7
Food consumed during 24 hour testing period	1.3	1.6	3.6	0.9	-1.1	1.0	1.7	1.9	0.1
Glucose	1.1	1.7	2.7	1.4	-1.6	1.6	1.1	1.2	0.5
Heart weight	0.8	1.1	1.9	1.4	-1.3	1.3	0.3	0.7	-0.7
Delay discount hyperbolic model param	0.1	0.1	0.2	0.5	0.2	-0.2	0.1	0.3	0.2
Intermittent access intake day 1-15 change	0.4	0.4	1.4	0.0	-0.0	0.0	-1.2	-1.0	0.2
Intermittent access intake escalation	0.3	0.3	1.0	-0.0	-0.2	0.2	-1.0	-0.7	0.2
Intermittent access intake escalation 2	0.2	0.2	0.5	-0.2	0.5	-0.5	-0.6	-0.4	0.7
Intermitt. access day 1 inactive lever presses	0.2	0.2	0.5	-0.3	-0.7	0.7	0.3	0.4	-0.5
Intermitt. access day 15 inactive lever presses	1.3	1.4	2.6	1.6	-1.1	1.1	-0.1	1.6	-0.9
Intermitt. access escalation Index	0.4	0.4	1.2	-0.4	0.6	-0.6	0.3	1.1	-0.3
Intermittent access day 1 total infusions	1.7	2.0	3.3	1.7	-1.8	1.8	0.1	1.4	-0.8
Intermittent access day 15 total infusions	1.1	1.2	2.5	1.3	-1.6	1.6	-0.6	0.3	-0.2
Intermittent access terminal intake (last 3 days)	0.9	0.9	1.9	1.3	-1.4	1.4	-0.4	0.1	-0.2
Intermittent access total infusions	1.8	2.0	3.8	1.9	-1.9	1.9	-0.1	0.9	-0.5
Intermittent access day 1 locomotion	1.1	1.1	2.5	1.6	-1.4	1.4	-0.1	0.4	-0.2
Intermittent access day 15 total locomotion	0.8	0.9	2.0	0.7	-0.8	0.8	-1.4	-1.2	0.1
Intermittent access total locomotion	0.9	1.1	2.3	1.3	-1.5	1.5	-0.6	-0.0	0.1
Intermittent access standard deviation	0.5	0.5	1.1	0.8	-0.8	0.8	-0.5	-1.1	0.4
Left kidney weight	1.0	2.8	4.7	1.8	-2.2	2.1	1.4	1.4	0.5
Right kidney weight	1.2	3.3	6.7	2.6	-2.4	2.4	0.3	1.2	-0.0
Cocaine induced anxiety	0.4	0.5	2.4	0.7	0.2	-0.2	0.0	-1.6	0.1
Post-drug Anxiety	0.7	0.8	2.5	0.8	-0.2	0.2	1.6	-0.2	1.2
Baseline Anxiety	1.9	2.0	4.5	-1.3	-0.1	0.1	2.1	1.9	1.6
Tail length	0.2	0.5	1.4	0.9	0.1	-0.1	-1.2	0.4	-0.8
Length with tail	0.3	1.0	2.4	1.4	-0.7	0.7	0.7	1.5	0.1
Length without tail	0.6	1.4	4.1	0.3	-0.5	0.5	2.0	1.1	1.4
Times rat made contact with spout	1.5	1.8	3.4	-1.0	0.9	-1.0	1.8	1.4	1.6
Lifetime Intake	1.8	2.1	3.8	2.0	-1.9	1.9	-0.2	0.6	-0.9
Liver weight, left	0.2	0.4	1.7	0.0	0.3	-0.3	0.4	-1.3	-0.1
Liver weight, right	0.3	0.4	1.7	-0.6	0.4	-0.3	0.1	-1.3	0.6
Locomotor activity	0.6	0.9	3.5	0.4	-0.8	0.8	1.9	0.4	0.7
Locomotor testing distance	1.0	1.6	2.7	1.1	-1.5	1.4	1.6	1.2	0.2
Locomotor testing rearing	1.7	2.7	5.0	0.1	-1.4	1.3	2.2	1.8	2.0
Locomotion in novel chamber	3.4	4.2	7.6	-2.3	2.7	-2.8	0.4	-0.5	2.0
Locomotion in novel chamber post-restriction	0.6	0.8	1.7	-1.3	0.9	-0.9	0.1	1.1	-0.4
Fecal boli incidents, locomotor time 1	0.4	0.4	1.3	0.1	-0.2	0.2	-0.9	-0.4	-1.1
Change in fecal boli incidents, locomotor task	0.7	0.6	1.6	0.5	-0.8	0.7	0.7	1.3	0.6
Time >=10cm from walls, locomotor time 1	1.4	1.4	5.1	-0.3	0.3	-0.3	1.5	-0.8	2.3
Bouts of movement, locomotor time 1	0.7	0.7	2.2	-0.6	0.2	-0.2	1.3	0.2	1.5
Total resting periods, locomotor time 1	0.4	0.4	1.3	-0.2	-0.1	0.1	1.1	0.1	1.0
Rest time, locomotor task time 1	0.2	0.3	0.8	-0.6	0.1	-0.1	-0.5	0.1	-0.9
Distance moved, locomotor task time 1	0.8	0.9	2.2	0.8	-0.8	0.7	1.5	0.5	0.9
Vertical activity count, locomotor time 1	0.3	0.3	1.3	0.4	0.1	-0.1	0.7	-0.0	1.1
Time >=10cm from walls, locomotor time 2	1.7	1.8	5.0	2.2	-1.5	1.5	-0.1	0.5	-0.9
Bouts of movement, locomotor time 2	0.3	0.3	1.6	-0.6	0.1	0.0	-0.0	-1.3	0.0
Total resting periods, locomotor time 2	0.3	0.3	1.5	-0.6	0.1	-0.0	-0.0	-1.2	0.1
Rest time, locomotor task time 2	0.2	0.3	1.2	-1.1	0.4	-0.3	-0.3	-0.1	-0.1
Distance moved, locomotor task time 2	0.1	0.1	0.4	0.7	0.0	-0.1	0.4	-0.3	-0.2
Vertical activity count, locomotor time 2	0.1	0.1	0.2	0.3	0.4	-0.5	-0.4	-0.0	0.0
Light reinforcement 1	1.7	3.1	9.1	3.0	-2.0	1.9	1.0	1.0	0.4
Light reinforcement 2	0.2	0.2	0.5	0.6	-0.1	0.1	0.7	0.6	0.2
Bone: marrow area	0.7	1.4	2.9	1.7	-1.6	1.6	-0.6	-0.3	-0.3
Bone: maximum diameter	1.2	2.3	5.1	2.3	-2.0	2.0	0.3	-0.2	0.4
Bone: maximum force	0.5	0.8	2.0	1.4	-0.6	0.5	1.1	-0.6	0.8
Bone: maximum moment	0.5	0.9	2.0	1.3	-0.5	0.5	1.4	-0.3	1.0
Mean time between licks in bursts	0.3	0.5	1.1	-0.1	-0.3	0.4	1.0	-0.9	0.8
Mean num. licks in bursts	0.6	0.8	1.8	-1.3	0.7	-0.7	-0.4	1.3	0.2
Cd content in liver	0.2	0.2	0.4	0.4	-0.6	0.6	0.5	-0.2	0.4
Co content in liver	1.8	2.1	5.2	2.3	-1.6	1.6	-0.4	0.9	-1.2
Cu content in liver	1.2	1.5	2.5	-1.5	1.1	-1.1	0.0	-1.3	1.6
Fe content in liver	1.5	1.7	2.6	-1.2	1.5	-1.5	-1.2	-1.6	0.5
K content in liver	1.1	1.0	1.8	-1.3	1.1	-1.0	-1.3	-0.5	0.5
Mg content in liver	0.6	0.6	1.9	-1.4	0.8	-0.8	-0.7	-0.1	0.3
Mn content in liver	0.6	0.6	1.3	0.0	-1.1	1.2	-0.1	0.5	1.0
Na content in liver	0.0	0.0	0.1	-0.2	-0.2	0.2	0.2	0.4	-0.1
Rb content in liver	0.5	0.6	1.8	0.4	-0.4	0.5	-1.3	-0.6	-1.1
Se content in liver	0.3	0.4	0.9	-0.9	0.5	-0.4	-0.9	-0.5	0.1
Sr content in liver	1.0	0.9	1.8	0.2	-1.3	1.3	-0.8	1.0	-0.6
Zn content in liver	6.0	6.6	11.5	-3.4	2.7	-2.7	0.7	-2.6	2.6
Bone: minimum diameter	2.6	4.9	10.3	3.2	-2.9	3.0	0.8	1.1	-0.2
Time in familiar zone, hab. session 1	1.1	1.1	2.3	0.4	1.5	-1.5	-1.1	-0.4	-0.6
Time in novel zone, hab. session 1	0.8	0.7	2.2	-0.2	-1.4	1.5	0.5	-0.2	-0.0
Total zone transitions, hab. session 1	1.0	1.3	4.2	1.8	-0.1	-0.0	-0.1	0.8	-2.0
Total locomotion distance, hab. session 1	0.3	0.4	0.8	0.6	0.8	-0.9	-0.4	0.1	-0.6
Locomotion velocity, hab. session 1	0.2	0.3	0.6	0.5	0.7	-0.8	-0.1	0.5	-0.1
Time in familiar zone, hab. session 2	0.5	0.5	1.6	-0.3	0.1	-0.1	-0.7	1.3	1.0
Time in novel zone, hab. session 2	0.7	0.7	2.4	-0.3	-0.4	0.4	0.3	-1.6	-1.0
Total zone transitions, hab. session 2	0.8	1.0	3.0	1.7	-0.9	0.8	0.8	0.4	-1.0
Total locomotion distance, hab. session 2	0.5	0.7	1.2	0.7	-1.1	1.1	0.9	0.7	0.3
Locomotion velocity, hab. session 2	0.3	0.4	0.8	0.5	-0.9	0.8	0.7	0.6	0.2
Novel to familiar place preference ratio	0.2	0.2	0.9	-0.2	-0.1	0.2	1.0	0.4	0.2
Novelty place preference	0.3	0.3	1.3	-0.1	-0.3	0.3	1.1	0.6	0.4
Time in novel zone, NPP test	0.5	0.5	2.1	-0.0	-0.3	0.3	1.5	0.7	0.5
Total zone transitions, NPP test	1.2	1.6	3.3	1.8	-1.6	1.6	0.4	0.9	-0.6
Total locomotion distance, NPP test	0.2	0.3	0.7	0.2	-0.4	0.3	0.6	0.4	0.8
Locomotion velocity, NPP test	0.2	0.3	1.0	0.0	-0.4	0.4	0.4	0.7	1.0
Intraocular pressure	0.3	0.4	1.1	-0.1	0.1	-0.1	-1.1	-0.8	-0.7
Delta distance traveled before/after self-admin	0.4	0.5	0.9	-0.5	-0.8	0.8	0.9	-0.7	0.3
Delta ambulatory time before/after self-admin	0.6	0.6	1.8	-0.4	-0.8	0.8	1.3	-0.5	0.5
Parametrial fat weight	0.4	0.8	2.4	-0.1	0.9	-0.9	0.2	-1.5	0.9
Pavlov. Cond. lever latency	0.6	0.7	3.2	0.4	-0.5	0.4	0.8	1.8	-0.1
Pavlov. Cond. magazine entry latency	0.5	0.6	1.1	1.1	-0.9	0.9	-0.1	-0.2	-1.0
Pavlov. Cond. change in total contacts	0.2	0.2	0.4	-0.5	0.4	-0.4	0.2	-0.6	-0.6
Pavlov. Cond. index score	0.1	0.2	0.6	-0.5	0.4	-0.3	-0.1	-0.8	0.1
Pavlov. Cond. latency score	0.3	0.4	1.2	-0.6	0.5	-0.5	-0.3	-1.1	0.1
Pavlov. Cond. lever contacts	0.2	0.2	0.8	-0.1	0.1	-0.0	-0.4	-0.9	0.5
Pavlov. Cond. magazine entry number	0.3	0.4	1.0	-0.6	0.6	-0.6	-0.1	0.0	1.0
Pavlov. Cond. intertrial magazine entries	0.2	0.3	1.0	-0.3	-0.2	0.2	-0.7	-1.0	0.2
Pavlov. Cond. lever-magazine prob. diff.	0.1	0.1	0.3	-0.6	0.2	-0.2	0.1	-0.4	0.3
Pavlov. Cond. response bias	0.2	0.2	0.4	0.5	-0.2	0.2	-0.3	-0.5	-0.6
Pavlov. Cond. lever latency	0.5	0.7	2.4	-1.5	0.7	-0.7	-0.8	-0.2	-0.4
Pavlov. Cond. magazine entry latency	0.3	0.4	1.8	-0.2	0.3	-0.3	-1.3	-0.2	-0.4
Pavlov. Cond. change in total contacts	0.2	0.3	0.6	0.6	-0.4	0.5	0.4	-0.3	0.7
Pavlov. Cond. index score	0.1	0.1	0.3	0.5	0.2	-0.2	-0.3	-0.3	0.4
Pavlov. Cond. latency score	0.2	0.2	0.4	0.0	0.5	-0.5	-0.3	-0.6	0.5
Pavlov. Cond. lever contacts	1.1	1.5	4.4	2.1	-1.4	1.4	0.4	0.5	0.4
Pavlov. Cond. magazine entry number	0.1	0.1	0.4	-0.1	-0.3	0.3	0.7	0.3	-0.1
Pavlov. Cond. intertrial magazine entries	0.5	0.6	1.2	0.7	-0.6	0.6	0.5	0.9	1.1
Pavlov. Cond. lever-magazine prob. diff.	0.1	0.1	0.2	0.5	0.2	-0.2	-0.3	-0.3	0.5
Pavlov. Cond. response bias	1.1	1.5	4.9	2.2	-1.4	1.4	-0.1	0.6	-0.1
Time in closed arm before self-admin	1.4	1.6	2.7	-1.1	1.6	-1.6	1.3	-0.5	1.0
Time in closed arm after self-admin	1.1	1.1	1.7	-0.7	1.3	-1.3	0.9	-1.3	0.8
Time in open arm before self-admin	1.3	1.4	3.9	1.1	-0.9	0.9	1.1	2.0	0.7
Time in open arm after self-admin	2.1	2.3	3.7	1.9	-1.9	1.9	-0.3	1.1	-1.2
Bone: periosteal estimation	1.4	2.9	6.3	2.5	-2.3	2.4	0.4	0.5	0.1
Bone: periosteal perimeter	1.7	2.9	6.1	2.5	-2.3	2.3	0.2	0.3	-0.6
Bone: post-yield work	0.5	0.7	3.0	0.6	0.6	-0.7	-0.2	-1.7	-0.1
Progressive ratio test 1 active lever presses	2.4	2.5	4.3	1.6	-2.1	2.1	-0.2	1.5	-1.2
Progressive ratio test 1 breakpoint	1.8	1.9	3.5	1.5	-1.9	1.9	0.1	1.3	-0.8
Progressive ratio test 1 inactive lever presses	0.6	0.7	1.2	0.0	-0.7	0.7	-1.0	1.0	-1.1
Progressive ratio test 2 active lever presses	0.7	0.7	1.5	0.8	-1.2	1.2	-0.2	1.0	-0.2
Progressive ratio test 2 breakpoint	0.8	0.9	2.3	0.7	-1.1	1.1	-0.1	1.5	-0.0
Progressive ratio test 2 inactive lever presses	0.6	0.7	1.3	0.8	-0.6	0.6	-0.9	0.9	-1.2
Incentive Sensitization - Responses	1.2	1.3	3.4	-0.8	1.2	-1.2	-1.8	-0.7	-0.2
Incentive Sensitization - Breakpoint	1.1	1.1	3.1	-0.8	1.2	-1.1	-1.8	-0.5	-0.1
Sum of active levers in priming session hrs 5-6	3.2	3.1	7.4	-2.7	1.2	-1.3	1.3	0.8	2.4
Progressive ratio	0.4	0.5	0.9	0.9	-0.6	0.6	-0.8	0.5	-0.5
Food seeking constrained by brief footshock	0.4	0.5	1.0	0.2	-0.8	0.8	0.6	0.7	1.0
Seeking ratio, punishment vs. effort	0.5	0.6	1.6	-0.9	0.1	-0.2	1.3	0.1	1.0
Retroperitoneal fat weight	1.1	3.7	7.3	2.6	-2.7	2.7	0.6	0.2	0.3
Reaction time number correct	0.2	0.4	1.3	0.4	-0.3	0.2	0.7	1.1	0.3
Reaction time mean minus median	1.4	1.9	3.6	-1.9	1.8	-1.7	-1.0	-0.3	-0.9
Reaction time mean minus median AUC	1.3	1.7	4.0	-2.0	1.5	-1.5	-1.1	-0.2	-0.5
Reaction time num false alarms	1.1	1.4	5.7	1.4	-0.5	0.5	-0.6	-0.5	-2.4
Reaction time num false alarms AUC	1.4	2.0	6.6	1.9	-0.7	0.6	-1.0	-0.3	-2.6
Reaction time trials correct on left	0.2	0.4	1.3	0.4	-0.3	0.2	0.7	1.1	0.3
Reaction time trials on left	0.2	0.3	1.2	0.3	-0.1	0.1	0.6	1.1	0.3
Reaction time mean	0.8	1.1	2.3	-1.5	1.2	-1.2	0.3	1.1	-0.2
Reaction time mean AUC	0.7	0.9	2.0	-1.4	0.9	-0.8	0.3	1.3	-0.4
Median of all reaction times	0.6	0.8	2.6	-0.9	0.6	-0.7	0.8	1.6	0.1
Reaction time omissions	1.8	2.5	4.4	-1.7	2.1	-2.1	-1.6	-0.7	-0.6
Reaction time false alarm rate	0.8	1.1	4.2	1.1	-0.2	0.2	-0.8	-0.8	-2.0
Reaction time premature initiation rate	1.9	2.5	7.5	2.7	-1.7	1.6	-0.6	0.5	-1.2
Reaction time premature initiations	2.0	2.8	8.1	2.8	-1.7	1.7	-0.4	1.1	-1.3
Std. dev. reaction times	2.0	2.8	5.4	-2.3	2.2	-2.1	-1.2	-0.6	-0.7
Reaction time trials completed	0.2	0.3	1.2	0.3	-0.1	0.1	0.6	1.1	0.3
Reaction time trials AUC	0.3	0.4	1.1	0.5	-0.3	0.3	0.8	1.1	0.4
Run reversals in cocaine runway, females	0.6	0.5	2.1	-1.4	0.4	-0.4	-0.1	0.8	0.3
Run reversals in cocaine runway, males	1.2	1.2	3.5	-1.0	-0.3	0.3	1.5	1.9	0.3
Latency to leave start box in cocaine runway	0.1	0.1	0.5	0.1	0.1	-0.1	-0.0	-0.1	0.7
Latency to leave start box in cocaine runway, F	0.3	0.3	0.4	0.6	-0.6	0.6	-0.0	-0.6	0.4
Latency to leave start box in cocaine runway, M	2.8	2.7	4.7	-1.6	2.2	-2.2	0.2	-0.4	2.0
Std. dev. time between licks in bursts	0.3	0.4	0.9	0.5	-0.4	0.3	0.9	-0.9	0.5
Total sessions with >9 infusions	2.5	2.8	4.8	2.2	-1.9	1.9	-0.4	0.1	-2.1
Short access day 1 total inactive lever presses	0.1	0.1	0.1	0.4	-0.3	0.3	0.2	0.3	-0.4
Short access day 10 total inactive lever presses	1.1	1.2	1.9	-1.3	1.1	-1.1	-1.4	-1.0	-0.4
Short access day 1 total infusions	0.9	1.0	2.1	0.5	-0.1	0.0	-1.4	-1.4	-1.3
Short access day 10 total infusions	1.7	1.9	3.5	1.6	-1.9	1.9	-0.2	0.5	-1.3
Short access total infusions	1.5	1.7	3.1	1.8	-1.6	1.6	-0.3	0.1	-1.4
Short access day 1 locomotion	0.5	0.5	2.6	0.7	-0.2	0.1	0.1	-1.6	-0.1
Short access day 10 total locomotion	0.3	0.3	1.1	-0.3	-0.4	0.4	0.3	-1.1	0.6
Short access total locomotion	0.7	0.7	1.4	1.0	-0.9	0.9	0.2	-1.2	0.3
One hour access (0.3 mA shock)	0.3	0.3	0.8	0.4	-0.9	0.9	-0.2	0.0	0.5
Compulsive drug intake	0.2	0.2	0.5	-0.7	-0.0	0.0	0.4	0.3	0.6
One hour access (shock baseline)	0.3	0.3	0.7	0.7	-0.8	0.9	-0.1	0.1	-0.0
Social response proportion	0.5	0.5	0.9	-0.2	0.8	-0.8	-1.0	-0.4	-0.8
Social responses	0.6	0.7	2.0	0.4	0.7	-0.8	0.9	0.4	1.4
Social time	1.2	1.6	3.5	-0.8	1.9	-1.9	-0.7	-1.0	0.4
Soleus weight	0.9	2.6	5.3	2.3	-1.9	1.9	-0.6	1.1	-1.2
Bone: stiffness	0.6	1.0	2.1	1.4	-0.9	0.9	1.4	0.0	0.7
Tibialis anterior weight	3.3	11.1	20.8	4.3	-3.5	3.5	1.6	4.6	-0.6
Time to tail flick, vehicle, before self-admin	0.3	0.3	0.8	-0.2	0.5	-0.5	-0.9	-0.3	-0.6
Time to tail flick, vehicle, after self-admin	0.6	0.6	2.6	0.3	0.4	-0.4	-0.9	-1.6	-0.0
Time to tail flick, test, before self-admin	0.7	0.7	1.3	-0.6	1.1	-1.1	-0.5	-1.0	-0.3
Time to tail flick, test, after self-admin	0.1	0.1	0.2	0.3	-0.2	0.1	0.5	0.1	0.2
Delta time to tail flick, vehicle, before/after SA	0.7	0.6	1.8	0.9	-0.8	0.7	-0.2	-1.3	0.2
Delta time to tail flick, test, before/after SA	0.7	0.6	1.3	0.8	-1.1	1.1	0.2	0.6	-0.2
Tibia length	0.4	1.2	2.4	1.1	-1.3	1.3	0.5	1.6	0.1
Ambulatory time before self-admin	0.6	0.6	3.5	0.1	0.2	-0.1	-1.9	-0.1	-0.3
Ambulatory time after self-admin	0.6	0.6	1.8	-0.4	-0.2	0.2	-1.3	-1.3	-0.0
Bone: tissue strength	1.1	1.1	4.0	0.5	-0.5	0.4	2.0	-0.1	1.3
Total heroin consumption	0.2	0.2	0.9	-0.4	0.1	-0.2	0.3	-0.2	0.9
Bone: trabecular number	0.5	0.8	1.5	-0.8	1.2	-1.2	-0.2	-1.2	-0.3
Bone: trabecular spacing	0.5	0.6	2.4	-0.6	-0.4	0.4	0.5	0.7	1.6
Bone: trabecular thickness	0.3	0.4	1.1	0.2	0.6	-0.6	0.4	0.6	-1.1
Bone: trabecular tissue density	0.3	0.4	1.4	-0.6	0.2	-0.2	-0.6	0.5	-1.2
Water consumed over 24 hours	0.6	0.7	2.8	0.2	0.0	-0.1	1.7	1.1	0.3
Number of responses in last shaping day	1.5	1.5	2.7	1.6	-1.2	1.2	-1.0	-0.5	-1.5