Hub : Traits

Bone: cortical thickness

Tags: Physiology · Bone

Project: r01_doug_adams

8 loci · 21 genes with independent associations · 77 total associated genes

Significant Loci

#	Chr	Start pos	End pos	# assoc genes	# joint models	Best TWAS P	Best GWAS P	Cond GWAS P	Joint genes
1	chr3	146614418	148660154	45	5	1.77e-08	1.75e-08	1.00e+00	Esf1 Ndufaf5
2	chr8	117463629	118343328	1	1	5.42e-25	1.52e-02	1.00e+00	Mst1
3	chr8	130995414	132376607	1	1	1.89e-09	7.72e-02	1.00e+00	Clec3b
4	chr9	83390749	84777604	1	1	0.00e+00	8.07e-01	1.00e+00	Retreg2
5	chr10	90948870	92930304	2	1	4.70e-08	1.81e-07	6.22e-01	Cep95
6	chr10	95109047	99430546	11	5	2.17e-12	9.13e-12	NaN	LOC102549521 LOC102549836 LOC134480721 LOC134480722 Map2k6
7	chr10	103498083	105333696	12	4	1.61e-08	1.45e-08	1.00e+00	Cyth1 Timp2 Usp36
8	chr10	106013117	107706829	4	3	4.85e-08	2.08e-08	2.77e-01	Fn3k Hexd Slc16a3

Pleiotropic Associations

Trait	Chi2 ratio	# genes+	# genes++	% genes++	Corr	Corr P	Genes
BMI with tail	113.82	9	1	4.8	0.94	1.85e-16	Esf1 Ism1 LOC134480909 Ndufaf5 Retreg2 Sptlc3 Tasp1 Timp2 Usp36
BMI without tail	13094.24	5	1	4.8	-0.95	6.56e-06	Esf1 Ndufaf5 Retreg2 Sptlc3 Tasp1
Body weight	5.29	11	5	23.8	0.66	5.61e-13	Esf1 Ism1 Mst1 Ndufaf5 Rab40b Retreg2 Slc16a3 Sptlc3 Tasp1 Timp2 Usp36
Epididymis fat weight	12053.52	6	2	9.5	-0.94	1.54e-04	Esf1 Mst1 Ndufaf5 Retreg2 Sptlc3 Tasp1
Glucose	827.12	3	2	9.5	0	1.00e+00	Fn3k Mst1 Retreg2
Heart weight	13509	1	1	4.8	0	1.00e+00	Retreg2
Left kidney weight	141259.46	1	1	4.8	0	1.00e+00	Retreg2
Right kidney weight	58428.02	2	2	9.5	0	1.00e+00	Mst1 Retreg2
Tail length	92117.69	1	1	4.8	0	1.00e+00	Retreg2
Length with tail	3073.73	2	2	9.5	0	1.00e+00	Mst1 Retreg2
Length without tail	25865.33	4	2	9.5	0.97	6.38e-03	Mst1 Retreg2 Timp2 Usp36
Liver weight, left	7266.72	2	2	9.5	0	1.00e+00	Mst1 Retreg2
Liver weight, right	101.84	3	3	14.3	0	1.00e+00	Clec3b Mst1 Retreg2
Parametrial fat weight	615.65	1	1	4.8	0	1.00e+00	Retreg2
Retroperitoneal fat weight	189.5	7	6	28.6	-0.6	8.85e-10	Esf1 Ism1 Mst1 Ndufaf5 Retreg2 Sptlc3 Tasp1
Intraocular pressure	40071.91	1	1	4.8	0	1.00e+00	Retreg2
Extensor digitorum longus weight	4682.69	1	1	4.8	0	1.00e+00	Retreg2
Soleus weight	115.65	1	1	4.8	0	1.00e+00	Retreg2
Tibialis anterior weight	4881.94	1	1	4.8	0	1.00e+00	Retreg2
Tibia length	40.29	12	6	28.6	-0.36	3.01e-04	Esf1 Fn3k Ism1 Mst1 Ndufaf5 Rab40b Retreg2 Slc16a3 Sptlc3 Tasp1 Timp2 Usp36
Number of licking bursts	157119.65	1	1	4.8	0	1.00e+00	Retreg2
Food consumed during 24 hour testing period	53101.62	2	1	4.8	0	1.00e+00	Mst1 Retreg2
Times rat made contact with spout	305.36	1	1	4.8	0	1.00e+00	Retreg2
Mean time between licks in bursts	199507.71	1	1	4.8	0	1.00e+00	Retreg2
Mean num. licks in bursts	142600.29	1	1	4.8	0	1.00e+00	Retreg2
Std. dev. time between licks in bursts	47024.7	2	1	4.8	0	1.00e+00	Clec3b Retreg2
Water consumed over 24 hours	103408.69	1	1	4.8	0	1.00e+00	Retreg2
Patch foraging indifference point 0 sec	115003.89	1	1	4.8	0	1.00e+00	Retreg2
Patch foraging indifference point AUC	66581.81	2	2	9.5	0	1.00e+00	Mst1 Retreg2
Indifference point function ln k	71040.92	2	2	9.5	0	1.00e+00	Mst1 Retreg2
Indifference point function log k	71040.92	2	2	9.5	0	1.00e+00	Mst1 Retreg2
Patch foraging total patch changes 0 sec	120264.14	1	1	4.8	0	1.00e+00	Retreg2
Patch foraging total patch changes 12 sec	5448.59	2	2	9.5	0	1.00e+00	Mst1 Retreg2
Patch foraging total patch changes 18 sec	29447.6	4	1	4.8	-0.96	3.81e-02	Mst1 Retreg2 Sptlc3 Tasp1
Patch foraging total patch changes 24 sec	83554.6	2	2	9.5	0	1.00e+00	Mst1 Retreg2
Patch foraging total patch changes 6 sec	32639.62	1	1	4.8	0	1.00e+00	Retreg2
Patch foraging time to switch 0 sec	156618.53	1	1	4.8	0	1.00e+00	Retreg2
Patch foraging water rate 0 sec	148807.58	1	1	4.8	0	1.00e+00	Retreg2
Patch foraging water rate 12 sec	161858.08	1	1	4.8	0	1.00e+00	Retreg2
Patch foraging water rate 18 sec	103280.07	1	1	4.8	0	1.00e+00	Retreg2
Patch foraging water rate 24 sec	2351.36	2	1	4.8	0	1.00e+00	Mst1 Retreg2
Patch foraging water rate 6 sec	3954.86	1	1	4.8	0	1.00e+00	Retreg2
Locomotor activity	15.72	2	1	4.8	0	1.00e+00	Mst1 Retreg2
Locomotor testing distance	44732.22	2	2	9.5	0	1.00e+00	Mst1 Retreg2
Locomotor testing rearing	25407.4	4	2	9.5	0.96	2.97e-03	Kcnj2 LOC134480721 Mst1 Retreg2
Light reinforcement 1	155242.72	1	1	4.8	0	1.00e+00	Retreg2
Light reinforcement 2	53965.57	2	2	9.5	0	1.00e+00	Mst1 Retreg2
Reaction time number correct	153465.22	1	1	4.8	0	1.00e+00	Retreg2
Reaction time mean minus median	205810.62	1	1	4.8	0	1.00e+00	Retreg2
Reaction time mean minus median AUC	104201.52	2	2	9.5	0	1.00e+00	Mst1 Retreg2
Reaction time num false alarms	28542.61	2	1	4.8	0	1.00e+00	Mst1 Retreg2
Reaction time num false alarms AUC	53251.53	2	1	4.8	0	1.00e+00	Mst1 Retreg2
Reaction time trials correct on left	153465.22	1	1	4.8	0	1.00e+00	Retreg2
Reaction time trials on left	149991.58	1	1	4.8	0	1.00e+00	Retreg2
Reaction time mean	47193.79	2	1	4.8	0	1.00e+00	Clec3b Retreg2
Reaction time mean AUC	113341.21	1	1	4.8	0	1.00e+00	Retreg2
Median of all reaction times	31417.12	1	1	4.8	0	1.00e+00	Retreg2
Reaction time omissions	34267.91	1	1	4.8	0	1.00e+00	Retreg2
Reaction time false alarm rate	451.08	2	1	4.8	0	1.00e+00	Mst1 Retreg2
Reaction time premature initiation rate	36877.02	1	1	4.8	0	1.00e+00	Retreg2
Reaction time premature initiations	138718.63	1	1	4.8	0	1.00e+00	Retreg2
Std. dev. reaction times	49833.07	3	1	4.8	0	1.00e+00	Clec3b Mst1 Retreg2
Reaction time trials completed	149991.58	1	1	4.8	0	1.00e+00	Retreg2
Reaction time trials AUC	151696.42	1	1	4.8	0	1.00e+00	Retreg2
Social response proportion	17657.99	2	1	4.8	0	1.00e+00	Mst1 Retreg2
Social responses	2847.52	2	1	4.8	0	1.00e+00	Mst1 Retreg2
Social time	44238.34	1	1	4.8	0	1.00e+00	Retreg2
Conditioned locomotion	6074.35	1	1	4.8	0	1.00e+00	Retreg2
Cocaine response after cond. corrected	65812.39	1	1	4.8	0	1.00e+00	Retreg2
Cocaine response after cond. not corrected	64247.35	1	1	4.8	0	1.00e+00	Retreg2
Cocaine response before conditioning	2800.41	1	1	4.8	0	1.00e+00	Retreg2
Saline control response	6522.43	2	2	9.5	0	1.00e+00	Mst1 Retreg2
Condit. Reinf. active minus inactive responses	26712.34	2	1	4.8	0	1.00e+00	Mst1 Retreg2
Condit. Reinf. active-inactive response ratio	91582.24	1	1	4.8	0	1.00e+00	Retreg2
Condit. Reinf. active responses	4856.3	2	2	9.5	0	1.00e+00	Mst1 Retreg2
Condit. Reinf. inactive responses	14050.12	3	2	9.5	0	1.00e+00	Clec3b Mst1 Retreg2
Condit. Reinf. lever presses	7960.29	2	2	9.5	0	1.00e+00	Mst1 Retreg2
Condit. Reinf. lever reinforcers received	1007.39	2	1	4.8	0	1.00e+00	Mst1 Retreg2
Pavlov. Cond. lever latency	5465.68	2	1	4.8	0	1.00e+00	Mst1 Retreg2
Pavlov. Cond. magazine entry latency	24773.4	2	2	9.5	0	1.00e+00	Mst1 Retreg2
Pavlov. Cond. change in total contacts	114781.94	1	1	4.8	0	1.00e+00	Retreg2
Pavlov. Cond. index score	24017.04	2	2	9.5	0	1.00e+00	Mst1 Retreg2
Pavlov. Cond. latency score	29259.45	2	2	9.5	0	1.00e+00	Mst1 Retreg2
Pavlov. Cond. lever contacts	11053	2	2	9.5	0	1.00e+00	Mst1 Retreg2
Pavlov. Cond. magazine entry number	8453.95	2	2	9.5	0	1.00e+00	Mst1 Retreg2
Pavlov. Cond. intertrial magazine entries	52501.71	2	2	9.5	0	1.00e+00	Mst1 Retreg2
Pavlov. Cond. lever-magazine prob. diff.	22461.1	2	2	9.5	0	1.00e+00	Mst1 Retreg2
Pavlov. Cond. response bias	2629.8	2	2	9.5	0	1.00e+00	Mst1 Retreg2
Conditioned reinforcement - actives	191492.54	1	1	4.8	0	1.00e+00	Retreg2
Conditioned reinforcement - inactives	77543.68	2	2	9.5	0	1.00e+00	Mst1 Retreg2
Conditioned locomotion	41346.85	1	1	4.8	0	1.00e+00	Retreg2
Intermittent access intake day 1-15 change	105304.97	2	1	4.8	0	1.00e+00	Mst1 Retreg2
Intermittent access intake escalation	104773.43	2	1	4.8	0	1.00e+00	Mst1 Retreg2
Intermittent access intake escalation 2	107995.31	1	1	4.8	0	1.00e+00	Retreg2
Intermitt. access day 1 inactive lever presses	47312.42	3	2	9.5	-0.99	4.65e-04	Mst1 Retreg2 Sox9
Intermitt. access day 15 inactive lever presses	208241.66	1	1	4.8	0	1.00e+00	Retreg2
Intermitt. access escalation Index	92516.01	2	2	9.5	0	1.00e+00	Mst1 Retreg2
Intermittent access day 1 total infusions	77765.1	2	1	4.8	0	1.00e+00	Mst1 Retreg2
Intermittent access day 15 total infusions	131485.34	1	1	4.8	0	1.00e+00	Retreg2
Intermittent access terminal intake (last 3 days)	83205.14	1	1	4.8	0	1.00e+00	Retreg2
Intermittent access total infusions	675.9	1	1	4.8	0	1.00e+00	Retreg2
Intermittent access day 1 locomotion	104459.41	1	1	4.8	0	1.00e+00	Retreg2
Intermittent access day 15 total locomotion	177836.92	1	1	4.8	0	1.00e+00	Retreg2
Intermittent access total locomotion	711.59	1	1	4.8	0	1.00e+00	Retreg2
Intermittent access standard deviation	100956.84	2	2	9.5	0	1.00e+00	Mst1 Retreg2
Cocaine induced anxiety	160280.46	1	1	4.8	0	1.00e+00	Retreg2
Post-drug Anxiety	20460.83	1	1	4.8	0	1.00e+00	Retreg2
Baseline Anxiety	103471.3	1	1	4.8	0	1.00e+00	Retreg2
Lifetime Intake	6830.03	1	1	4.8	0	1.00e+00	Retreg2
Incentive Sensitization - Responses	163579.25	1	1	4.8	0	1.00e+00	Retreg2
Incentive Sensitization - Breakpoint	142790.8	1	1	4.8	0	1.00e+00	Retreg2
Progressive ratio test 1 active lever presses	99872.69	1	1	4.8	0	1.00e+00	Retreg2
Progressive ratio test 1 breakpoint	96247.61	1	1	4.8	0	1.00e+00	Retreg2
Progressive ratio test 1 inactive lever presses	75556.75	2	2	9.5	0	1.00e+00	Mst1 Retreg2
Progressive ratio test 2 active lever presses	57222.6	1	1	4.8	0	1.00e+00	Retreg2
Progressive ratio test 2 breakpoint	34975.96	1	1	4.8	0	1.00e+00	Retreg2
Progressive ratio test 2 inactive lever presses	164104.71	1	1	4.8	0	1.00e+00	Retreg2
Total sessions with >9 infusions	3995.08	2	2	9.5	0	1.00e+00	Mst1 Retreg2
Short access day 1 total inactive lever presses	57219.08	2	2	9.5	0	1.00e+00	Mst1 Retreg2
Short access day 10 total inactive lever presses	108578.43	2	2	9.5	0	1.00e+00	Mst1 Retreg2
Short access day 1 total infusions	111479.43	1	1	4.8	0	1.00e+00	Retreg2
Short access day 10 total infusions	38157.63	2	2	9.5	0	1.00e+00	Mst1 Retreg2
Short access total infusions	33946.03	1	1	4.8	0	1.00e+00	Retreg2
Short access day 1 locomotion	84055.65	1	1	4.8	0	1.00e+00	Retreg2
Short access day 10 total locomotion	90801.14	2	1	4.8	0	1.00e+00	Mst1 Retreg2
Short access total locomotion	34144.06	2	2	9.5	0	1.00e+00	Mst1 Retreg2
Compulsive drug intake	65439.45	1	1	4.8	0	1.00e+00	Retreg2
One hour access (0.3 mA shock)	9669.44	1	1	4.8	0	1.00e+00	Retreg2
One hour access (shock baseline)	140263.4	1	1	4.8	0	1.00e+00	Retreg2
Number of responses in last shaping day	51289.19	1	1	4.8	0	1.00e+00	Retreg2
Context. condit. distance diff. score	970.59	1	1	4.8	0	1.00e+00	Retreg2
Locomotion velocity, session 1	14615.25	1	1	4.8	0	1.00e+00	Retreg2
Locomotion distance, session 1	2214.83	2	1	4.8	0	1.00e+00	Clec3b Retreg2
Locomotion velocity, session 2	4702.2	2	2	9.5	0	1.00e+00	Mst1 Retreg2
Locomotion distance, session 2	1204.92	2	1	4.8	0	1.00e+00	Clec3b Retreg2
Locomotion velocity, session 3	2332.53	1	1	4.8	0	1.00e+00	Retreg2
Locomotion distance, session 3	16615.78	1	1	4.8	0	1.00e+00	Retreg2
Stereotopy head waving bouts, day 3	2943.11	2	1	4.8	0	1.00e+00	Mst1 Retreg2
Stereotopy head waving duration, day 3	6074.03	2	1	4.8	0	1.00e+00	Mst1 Retreg2
Locomotion velocity, session 7	708.6	2	2	9.5	0	1.00e+00	Mst1 Retreg2
Locomotion distance, session 7	1934.91	2	2	9.5	0	1.00e+00	Mst1 Retreg2
Stereotopy head waving bouts, day 7	5243.79	2	1	4.8	0	1.00e+00	Clec3b Retreg2
Stereotopy head waving duration, day 7	4434.07	2	1	4.8	0	1.00e+00	Clec3b Retreg2
Locomotion velocity, session 8	1892.98	1	1	4.8	0	1.00e+00	Retreg2
Locomotion distance, session 8	673.32	1	1	4.8	0	1.00e+00	Retreg2
Degree of sensitization distance	7696.03	2	2	9.5	0	1.00e+00	Mst1 Retreg2
Degree of sensitization stereotypy	4256.71	2	1	4.8	0	1.00e+00	Clec3b Retreg2
Condit. Reinf. active minus inactive responses	4120.78	1	1	4.8	0	1.00e+00	Retreg2
Condit. Reinf. active-inactive response ratio	1097.66	1	1	4.8	0	1.00e+00	Retreg2
Condit. Reinf. active responses	11664.93	1	1	4.8	0	1.00e+00	Retreg2
Condit. Reinf. inactive responses	6465.58	3	1	4.8	0	1.00e+00	Clec3b Mst1 Retreg2
Incentive salience index mean	7398.25	2	1	4.8	0	1.00e+00	Mst1 Retreg2
Condit. Reinf. lever presses	7160.97	3	2	9.5	0	1.00e+00	Clec3b Mst1 Retreg2
Time in familiar zone, hab. session 1	41873.03	1	1	4.8	0	1.00e+00	Retreg2
Time in novel zone, hab. session 1	17770.84	2	1	4.8	0	1.00e+00	Mst1 Retreg2
Total zone transitions, hab. session 1	1818.53	1	1	4.8	0	1.00e+00	Retreg2
Total locomotion distance, hab. session 1	1687	1	1	4.8	0	1.00e+00	Retreg2
Locomotion velocity, hab. session 1	1131.06	1	1	4.8	0	1.00e+00	Retreg2
Time in familiar zone, hab. session 2	11707.23	2	2	9.5	0	1.00e+00	Mst1 Retreg2
Time in novel zone, hab. session 2	12499.19	2	2	9.5	0	1.00e+00	Mst1 Retreg2
Total zone transitions, hab. session 2	145.6	2	1	4.8	0	1.00e+00	Mst1 Retreg2
Total locomotion distance, hab. session 2	96.8	1	1	4.8	0	1.00e+00	Retreg2
Locomotion velocity, hab. session 2	81.66	2	1	4.8	0	1.00e+00	Clec3b Retreg2
Novel to familiar place preference ratio	27762.34	2	1	4.8	0	1.00e+00	Mst1 Retreg2
Novelty place preference	27201.76	2	1	4.8	0	1.00e+00	Mst1 Retreg2
Time in novel zone, NPP test	13623.96	3	1	4.8	0	1.00e+00	Clec3b Mst1 Retreg2
Total zone transitions, NPP test	4120.91	2	1	4.8	0	1.00e+00	Clec3b Retreg2
Total locomotion distance, NPP test	7114	1	1	4.8	0	1.00e+00	Retreg2
Locomotion velocity, NPP test	4041.22	1	1	4.8	0	1.00e+00	Retreg2
Pavlov. Cond. lever latency	752.85	3	2	9.5	0	1.00e+00	Clec3b Mst1 Retreg2
Pavlov. Cond. change in total contacts	2282.17	2	1	4.8	0	1.00e+00	Clec3b Retreg2
Pavlov. Cond. index score	607.39	3	3	14.3	0	1.00e+00	Clec3b Mst1 Retreg2
Pavlov. Cond. latency score	630.11	3	2	9.5	0	1.00e+00	Clec3b Mst1 Retreg2
Pavlov. Cond. lever contacts	1038.61	3	3	14.3	0	1.00e+00	Clec3b Mst1 Retreg2
Pavlov. Cond. magazine entry number	2162.19	1	1	4.8	0	1.00e+00	Retreg2
Pavlov. Cond. intertrial magazine entries	277.69	2	2	9.5	0	1.00e+00	Mst1 Retreg2
Pavlov. Cond. lever-magazine prob. diff.	662.24	3	2	9.5	0	1.00e+00	Clec3b Mst1 Retreg2
Pavlov. Cond. response bias	882.63	3	2	9.5	0	1.00e+00	Clec3b Mst1 Retreg2
Bone: apparent density	22268.03	1	1	4.8	0	1.00e+00	Retreg2
Bone surface	2522.52	8	3	14.3	-0.95	3.21e-05	Abca5 Kcnj16 Kcnj2 LOC134480721 LOC134480722 Map2k6 Mst1 Retreg2
Bone volume	4235.95	6	1	4.8	-0.95	2.63e-04	Abca5 Kcnj16 Kcnj2 LOC134480721 Mst1 Retreg2
Bone: connectivity density	7098.55	1	1	4.8	0	1.00e+00	Retreg2
Bone: cortical apparent density	11325.37	3	1	4.8	1	6.22e-05	Ccdc47 Clec3b Retreg2
Bone: cortical area	229.03	11	2	9.5	-0.56	2.28e-08	Clec3b Esf1 Fn3k Hexd Ism1 Mst1 Ndufaf5 Rab40b Retreg2 Slc16a3 Tasp1
Bone: cortical porosity	926.55	2	1	4.8	0	1.00e+00	Clec3b Retreg2
Bone: cortical porosity	4807.78	1	1	4.8	0	1.00e+00	Retreg2
Bone: cortical thickness	6116.53	2	2	9.5	0	1.00e+00	Mst1 Retreg2
Bone: cortical tissue density	12121.25	3	1	4.8	1	7.76e-05	Ccdc47 Clec3b Retreg2
Bone: elastic displacement	14829.24	2	2	9.5	0	1.00e+00	Clec3b Retreg2
Bone: elastic work	161.98	8	3	14.3	0.99	3.44e-09	Clec3b LOC102549521 LOC102549836 Mst1 Rab40b Retreg2 Slc16a3 Sox9
Bone: endosteal estimation	1114.66	17	11	52.4	-0.91	2.86e-13	Abca5 C1qtnf1 Ccdc47 Cep95 Cyth1 Kcnj16 Kcnj2 LOC102549521 LOC102549596 LOC102549836 LOC134480721 LOC134480722 LOC134480909 Map2k6 Retreg2 Timp2 Usp36
Bone: endosteal perimeter	1408.9	19	11	52.4	-0.89	8.22e-12	Abca5 C1qtnf1 Ccdc47 Cep95 Cyth1 Kcnj16 Kcnj2 LOC102549521 LOC102549596 LOC102549836 LOC134480721 LOC134480722 LOC134480909 Map2k6 Mst1 Retreg2 Sox9 Timp2 Usp36
Bone: final force	1424.95	5	2	9.5	-0.91	3.07e-02	Clec3b Mst1 Rab40b Retreg2 Slc16a3
Bone: final moment	228.14	5	2	9.5	-0.82	9.20e-02	Clec3b Mst1 Rab40b Retreg2 Slc16a3
Bone: marrow area	1170.84	18	11	52.4	-0.89	5.24e-12	Abca5 C1qtnf1 Ccdc47 Cep95 Cyth1 Kcnj16 Kcnj2 LOC102549521 LOC102549596 LOC102549836 LOC134480721 LOC134480722 LOC134480909 Map2k6 Mst1 Retreg2 Timp2 Usp36
Bone: maximum diameter	2724.18	6	2	9.5	-0.95	1.06e-04	Kcnj16 Kcnj2 LOC134480721 LOC134480722 Mst1 Retreg2
Bone: maximum force	8658.9	4	2	9.5	-0.95	5.46e-02	Mst1 Rab40b Retreg2 Slc16a3
Bone: maximum moment	6199.89	4	3	14.3	-0.94	5.83e-02	Mst1 Rab40b Retreg2 Slc16a3
Bone: minimum diameter	1442.39	9	2	9.5	-0.95	3.29e-06	Abca5 Ccdc47 Kcnj16 Kcnj2 LOC134480721 LOC134480722 Map2k6 Mst1 Retreg2
Bone: periosteal estimation	2947.88	9	3	14.3	-0.94	2.19e-06	Abca5 Ccdc47 Kcnj16 Kcnj2 LOC134480721 LOC134480722 Map2k6 Mst1 Retreg2
Bone: periosteal perimeter	7207.69	6	2	9.5	-0.95	3.62e-03	Kcnj16 Kcnj2 LOC134480722 Mst1 Rab40b Retreg2
Bone: post-yield work	16956.69	3	1	4.8	0	1.00e+00	Clec3b Mst1 Retreg2
Bone: stiffness	17808.98	2	2	9.5	0	1.00e+00	Mst1 Retreg2
Bone: tissue strength	12264.67	1	1	4.8	0	1.00e+00	Retreg2
Bone: trabecular number	41138.39	1	1	4.8	0	1.00e+00	Retreg2
Bone: trabecular spacing	15656.57	2	2	9.5	0	1.00e+00	Mst1 Retreg2
Bone: trabecular thickness	16647.3	2	2	9.5	0	1.00e+00	Mst1 Retreg2
Bone: trabecular tissue density	26817.91	2	2	9.5	0	1.00e+00	Mst1 Retreg2
Breakpoint value in progressive ratio session	37483.72	3	2	9.5	0	1.00e+00	Clec3b Mst1 Retreg2
Distance traveled before self-admin	134013.73	1	1	4.8	0	1.00e+00	Retreg2
Distance traveled after self-admin	100820.36	1	1	4.8	0	1.00e+00	Retreg2
Delta time in closed arm before/after self-admin	1271.86	1	1	4.8	0	1.00e+00	Retreg2
Delta time in open arm before/after self-admin	54811.83	1	1	4.8	0	1.00e+00	Retreg2
Diff in mean of infusions in LGA sessions	54252.87	2	1	4.8	0	1.00e+00	Mst1 Retreg2
Extinction: sum of active levers before priming	30541.42	3	2	9.5	0	1.00e+00	Clec3b Mst1 Retreg2
Active lever presses in extinction session 6	1571.88	2	1	4.8	0	1.00e+00	Mst1 Retreg2
Delta distance traveled before/after self-admin	12434.77	1	1	4.8	0	1.00e+00	Retreg2
Delta ambulatory time before/after self-admin	96034.01	1	1	4.8	0	1.00e+00	Retreg2
Time in closed arm before self-admin	44133.6	2	2	9.5	0	1.00e+00	Mst1 Retreg2
Time in closed arm after self-admin	9759.54	2	2	9.5	0	1.00e+00	Mst1 Retreg2
Time in open arm before self-admin	34587.99	1	1	4.8	0	1.00e+00	Retreg2
Time in open arm after self-admin	979.73	2	2	9.5	0	1.00e+00	Mst1 Retreg2
Sum of active levers in priming session hrs 5-6	3877.89	1	1	4.8	0	1.00e+00	Retreg2
Time to tail flick, vehicle, before self-admin	25677.46	2	1	4.8	0	1.00e+00	Mst1 Retreg2
Time to tail flick, vehicle, after self-admin	118286.85	1	1	4.8	0	1.00e+00	Retreg2
Time to tail flick, test, before self-admin	32803.11	1	1	4.8	0	1.00e+00	Retreg2
Time to tail flick, test, after self-admin	5828.87	1	1	4.8	0	1.00e+00	Retreg2
Delta time to tail flick, vehicle, before/after SA	18281.67	2	2	9.5	0	1.00e+00	Mst1 Retreg2
Delta time to tail flick, test, before/after SA	56832.34	1	1	4.8	0	1.00e+00	Retreg2
Ambulatory time before self-admin	171079.71	1	1	4.8	0	1.00e+00	Retreg2
Ambulatory time after self-admin	88230.17	1	1	4.8	0	1.00e+00	Retreg2
Total heroin consumption	961.5	1	1	4.8	0	1.00e+00	Retreg2
Area under the delay curve	81605.23	1	1	4.8	0	1.00e+00	Retreg2
Delay disc. indifference point, 0s delay	9477.47	1	1	4.8	0	1.00e+00	Retreg2
Delay disc. indifference point, 16s delay	74803.61	1	1	4.8	0	1.00e+00	Retreg2
Delay disc. indifference point, 2s delay	825.84	1	1	4.8	0	1.00e+00	Retreg2
Delay disc. indifference point, 24s delay	49996.07	2	1	4.8	0	1.00e+00	Clec3b Retreg2
Delay disc. indifference point, 4s delay	2525.7	1	1	4.8	0	1.00e+00	Retreg2
Delay disc. indifference point, 8s delay	101423.99	1	1	4.8	0	1.00e+00	Retreg2
Delay discount exponential model param	60214.95	1	1	4.8	0	1.00e+00	Retreg2
Delay discount hyperbolic model param	45715.54	1	1	4.8	0	1.00e+00	Retreg2
Fecal boli incidents, locomotor time 1	150160.89	1	1	4.8	0	1.00e+00	Retreg2
Change in fecal boli incidents, locomotor task	23481.3	1	1	4.8	0	1.00e+00	Retreg2
Time >=10cm from walls, locomotor time 1	49255.61	1	1	4.8	0	1.00e+00	Retreg2
Bouts of movement, locomotor time 1	41590.88	1	1	4.8	0	1.00e+00	Retreg2
Total resting periods, locomotor time 1	11802.64	1	1	4.8	0	1.00e+00	Retreg2
Rest time, locomotor task time 1	75951.88	1	1	4.8	0	1.00e+00	Retreg2
Distance moved, locomotor task time 1	159283.67	1	1	4.8	0	1.00e+00	Retreg2
Vertical activity count, locomotor time 1	219061.96	1	1	4.8	0	1.00e+00	Retreg2
Time >=10cm from walls, locomotor time 2	161986.9	1	1	4.8	0	1.00e+00	Retreg2
Bouts of movement, locomotor time 2	174298.32	1	1	4.8	0	1.00e+00	Retreg2
Total resting periods, locomotor time 2	190079.87	1	1	4.8	0	1.00e+00	Retreg2
Rest time, locomotor task time 2	83778.18	1	1	4.8	0	1.00e+00	Retreg2
Distance moved, locomotor task time 2	34268.85	1	1	4.8	0	1.00e+00	Retreg2
Vertical activity count, locomotor time 2	138414.05	1	1	4.8	0	1.00e+00	Retreg2
Weight adjusted by age	161973.18	1	1	4.8	0	1.00e+00	Retreg2
Seeking ratio, delayed vs. immediate footshock	49395.56	1	1	4.8	0	1.00e+00	Retreg2
Locomotion in novel chamber	16301.47	1	1	4.8	0	1.00e+00	Retreg2
Locomotion in novel chamber post-restriction	154642.04	1	1	4.8	0	1.00e+00	Retreg2
Progressive ratio	157894.89	1	1	4.8	0	1.00e+00	Retreg2
Food seeking constrained by brief footshock	7338.76	1	1	4.8	0	1.00e+00	Retreg2
Seeking ratio, punishment vs. effort	118281.2	1	1	4.8	0	1.00e+00	Retreg2
Run reversals in cocaine runway, females	37174.37	1	1	4.8	0	1.00e+00	Retreg2
Run reversals in cocaine runway, males	29861.56	1	1	4.8	0	1.00e+00	Retreg2
Latency to leave start box in cocaine runway	58575.8	1	1	4.8	0	1.00e+00	Retreg2
Latency to leave start box in cocaine runway, F	28379.24	1	1	4.8	0	1.00e+00	Retreg2
Latency to leave start box in cocaine runway, M	7140.1	1	1	4.8	0	1.00e+00	Retreg2
Co content in liver	4721.74	1	1	4.8	0	1.00e+00	Retreg2
Cu content in liver	162.43	1	1	4.8	0	1.00e+00	Retreg2
Fe content in liver	5656.2	1	1	4.8	0	1.00e+00	Retreg2
K content in liver	6593.53	1	1	4.8	0	1.00e+00	Retreg2
Mg content in liver	24493.99	1	1	4.8	0	1.00e+00	Retreg2
Mn content in liver	4374.36	1	1	4.8	0	1.00e+00	Retreg2
Na content in liver	16641.94	1	1	4.8	0	1.00e+00	Retreg2
Rb content in liver	428.45	1	1	4.8	0	1.00e+00	Retreg2
Zn content in liver	15755.62	1	1	4.8	0	1.00e+00	Retreg2

Associations by panel

Tissue	RNA modality	# hits	% hits/tests	Avg chisq
Adipose	alternative polyA	0	0	1.6
Adipose	alternative TSS	0	0	1.78
Adipose	gene expression	2	0	1.61
Adipose	isoform ratio	1	0	1.65
Adipose	intron excision ratio	3	0.1	1.69
Adipose	mRNA stability	2	0	1.68
BLA	alternative polyA	0	0	1.66
BLA	alternative TSS	2	0.1	1.61
BLA	gene expression	2	0	1.67
BLA	isoform ratio	4	0.1	1.69
BLA	intron excision ratio	2	0.1	1.71
BLA	mRNA stability	0	0	1.63
Brain	alternative polyA	0	0	1.63
Brain	alternative TSS	4	0.1	1.73
Brain	gene expression	7	0.1	1.67
Brain	isoform ratio	7	0.1	1.73
Brain	intron excision ratio	5	0.1	1.76
Brain	mRNA stability	3	0.1	1.68
Eye	alternative polyA	0	0	2.07
Eye	alternative TSS	0	0	1.73
Eye	gene expression	1	0.1	1.76
Eye	isoform ratio	0	0	1.77
Eye	intron excision ratio	1	0.1	1.55
Eye	mRNA stability	0	0	1.6
IC	alternative polyA	0	0	1.75
IC	alternative TSS	1	0.1	1.75
IC	gene expression	4	0.1	1.69
IC	isoform ratio	2	0.1	1.8
IC	intron excision ratio	4	0.1	1.68
IC	mRNA stability	0	0	1.54
IL	alternative polyA	0	0	1.67
IL	alternative TSS	0	0	1.63
IL	gene expression	4	0.1	1.68
IL	isoform ratio	0	0	1.72
IL	intron excision ratio	0	0	1.66
IL	mRNA stability	0	0	1.68
LHb	alternative polyA	0	0	1.66
LHb	alternative TSS	0	0	1.7
LHb	gene expression	7	0.2	1.77
LHb	isoform ratio	0	0	1.58
LHb	intron excision ratio	0	0	1.51
LHb	mRNA stability	0	0	1.73
Liver	alternative polyA	0	0	1.71
Liver	alternative TSS	0	0	1.7
Liver	gene expression	2	0	1.64
Liver	isoform ratio	2	0.1	1.77
Liver	intron excision ratio	1	0	1.55
Liver	mRNA stability	0	0	1.66
NAcc	alternative polyA	2	0.1	2.35
NAcc	alternative TSS	2	0.1	1.62
NAcc	gene expression	4	0	1.67
NAcc	isoform ratio	4	0.1	1.68
NAcc	intron excision ratio	5	0.1	1.71
NAcc	mRNA stability	0	0	1.66
OFC	alternative polyA	0	0	1.71
OFC	alternative TSS	0	0	1.74
OFC	gene expression	3	0.1	1.72
OFC	isoform ratio	0	0	1.7
OFC	intron excision ratio	2	0.2	1.71
OFC	mRNA stability	0	0	1.64
PL	alternative polyA	0	0	1.64
PL	alternative TSS	2	0.1	1.68
PL	gene expression	4	0	1.68
PL	isoform ratio	9	0.2	1.71
PL	intron excision ratio	5	0.1	1.68
PL	mRNA stability	0	0	1.63
pVTA	alternative polyA	3	0.1	1.63
pVTA	alternative TSS	2	0.1	1.67
pVTA	gene expression	4	0.1	1.72
pVTA	isoform ratio	6	0.2	1.74
pVTA	intron excision ratio	6	0.1	1.65
pVTA	mRNA stability	0	0	1.63
RMTg	alternative polyA	0	0	1.44
RMTg	alternative TSS	0	0	1.6
RMTg	gene expression	0	0	1.71
RMTg	isoform ratio	4	0.5	1.72
RMTg	intron excision ratio	1	0.1	1.8
RMTg	mRNA stability	0	0	1.67