Hub : Genes

Rpl19

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Eye gene expression Rpl19 0.59 0.19 1.0e-05 0.12 0.08 0.17 0.17 7.6e-03 2.1e-02 1.6e-03 1.5e-03
2 Adipose gene expression Rpl19 0.47 0.16 0.0e+00 0.48 0.48 0.48 0.49 9.1e-61 2.1e-60 2.2e-60 1.5e-61
3 OFC intron excision ratio chr10_83514914_83519902 0.39 0.22 9.5e-07 0.13 0.08 0.18 0.16 5.9e-04 5.1e-03 5.2e-05 1.2e-04
4 Adipose isoform ratio XM_039086939.2 0.37 0.18 0.0e+00 0.28 0.29 0.29 0.29 9.5e-32 1.7e-32 1.7e-32 1.8e-32
5 PL intron excision ratio chr10_83519096_83519902 0.18 0.1 0.0e+00 0.14 0.15 0.15 0.15 1.5e-15 1.8e-16 5.3e-16 4.9e-16
6 PL gene expression Rpl19 0.16 0.1 6.1e-14 0.1 0.11 0.1 0.1 2.9e-11 9.8e-12 2.9e-11 3.8e-11
7 IC gene expression Rpl19 0.39 0.19 1.8e-09 0.16 0.17 0.18 0.17 3.2e-07 9.0e-08 3.5e-08 9.2e-08
8 IC intron excision ratio chr10_83519096_83519902 0.24 0.13 8.6e-10 0.24 0.2 0.22 0.22 2.8e-10 1.0e-08 1.1e-09 9.2e-10
9 IC intron excision ratio chr10_83514914_83519902 0.24 0.13 5.9e-10 0.24 0.2 0.22 0.22 1.6e-10 7.8e-09 1.3e-09 2.1e-09
10 Brain intron excision ratio chr10_83519096_83519902 0.09 0.11 2.4e-04 0.03 0.03 0.04 0.04 4.0e-04 3.6e-04 3.0e-04 1.2e-04
11 PL intron excision ratio chr10_83514914_83519902 0.21 0.13 0.0e+00 0.18 0.16 0.17 0.17 1.7e-19 1.1e-17 9.5e-18 4.6e-18
12 Liver gene expression Rpl19 0.18 0.14 0.0e+00 0.14 0.14 0.14 0.14 1.8e-15 4.1e-15 5.6e-15 4.3e-15
13 Adipose isoform ratio NM_031103.1 0.37 0.18 0.0e+00 0.31 0.32 0.32 0.32 3.6e-35 1.1e-35 1.0e-35 6.5e-36
14 NAcc isoform ratio NM_031103.1 0.05 0.04 2.4e-07 0.05 0.05 0.04 0.05 4.1e-08 8.2e-08 5.1e-07 9.7e-08
15 IL intron excision ratio chr10_83514914_83519902 0.28 0.28 1.6e-03 0.1 0.03 0.07 0.1 2.1e-03 5.8e-02 7.3e-03 2.6e-03
16 BLA gene expression Rpl19 0.19 0.11 5.1e-09 0.11 0.12 0.08 0.1 3.1e-06 8.4e-07 6.9e-05 3.7e-06
17 NAcc gene expression Rpl19 0.22 0.11 0.0e+00 0.26 0.26 0.27 0.27 9.5e-39 4.9e-40 1.5e-40 1.4e-40
18 IL gene expression Rpl19 0.3 0.45 3.1e-03 0.08 0.05 0.06 0.07 6.3e-03 2.9e-02 1.8e-02 8.9e-03
19 RMTg gene expression Rpl19 0.13 0.1 4.7e-03 0.08 0.01 0.03 0.04 3.7e-03 1.5e-01 6.6e-02 2.7e-02
20 Brain gene expression Rpl19 0.29 0.12 0.0e+00 0.28 0.3 0.28 0.3 3.0e-26 6.4e-28 1.2e-26 5.4e-28
21 OFC gene expression Rpl19 0.37 0.28 1.2e-04 0.12 0.04 0.08 0.12 1.0e-03 5.0e-02 7.4e-03 7.3e-04

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21
Bone: apparent density2.23.86.31.92.0-2.3-1.92.02.02.02.0-2.01.9-2.02.01.91.9-2.51.92.01.91.92.10.0
Area under the delay curve0.80.91.51.20.8-0.9-0.91.01.01.01.0-1.01.1-1.00.90.81.0-0.71.11.20.90.91.10.0
BMI with tail2.06.77.9-2.5-2.82.42.7-2.7-2.7-2.8-2.62.6-2.52.8-2.8-2.7-2.62.1-2.6-2.6-2.8-2.8-2.70.0
BMI without tail1.44.36.3-2.2-2.31.42.3-2.3-2.3-2.3-1.81.8-2.32.5-2.5-2.3-2.20.8-2.2-2.2-1.7-1.7-2.40.0
Body weight7.131.036.1-5.9-6.05.46.0-5.9-5.9-5.8-5.35.3-5.95.9-6.0-5.9-5.94.7-5.8-5.8-5.2-5.2-5.80.0
Weight adjusted by age0.20.20.9-0.4-0.30.80.3-0.3-0.3-0.4-0.50.5-0.30.3-0.5-0.3-0.21.0-0.4-0.4-0.8-0.8-0.20.0
Bone surface0.00.10.6-0.00.1-0.40.00.10.10.10.4-0.4-0.1-0.10.1-0.0-0.1-0.7-0.00.10.20.20.30.0
Bone volume0.20.30.90.40.5-0.7-0.40.40.40.50.7-0.70.3-0.50.50.40.3-0.90.40.50.50.50.70.0
Breakpoint value in progressive ratio session1.51.83.4-1.5-1.30.91.6-1.5-1.5-1.3-0.90.9-1.61.6-1.5-1.5-1.90.6-1.5-1.6-0.6-0.6-1.60.0
Number of licking bursts0.30.50.80.70.8-0.4-0.90.80.80.80.6-0.60.8-0.90.90.90.8-0.20.80.70.50.50.80.0
Context. condit. distance diff. score0.70.82.0-0.9-0.81.10.7-0.8-0.8-0.9-1.01.0-0.70.7-0.7-0.7-0.61.4-0.7-0.9-1.1-1.1-0.90.0
Locomotion velocity, session 10.70.71.1-0.8-1.00.81.0-1.0-0.9-0.8-0.80.8-1.00.9-0.9-1.0-1.00.4-1.1-0.9-0.6-0.6-0.90.0
Locomotion distance, session 13.24.05.9-2.2-2.21.42.3-2.2-2.2-2.2-1.71.7-2.42.4-2.4-2.3-2.40.8-2.3-2.1-1.5-1.5-2.00.0
Locomotion velocity, session 20.50.60.9-0.8-0.80.40.9-0.8-0.8-0.7-0.70.7-0.90.8-0.8-0.9-1.00.0-0.9-0.8-0.5-0.5-0.80.0
Locomotion distance, session 20.60.91.7-1.1-1.00.21.2-1.1-1.0-1.0-0.60.6-1.21.3-1.3-1.2-1.3-0.4-1.2-1.0-0.2-0.2-0.80.0
Locomotion velocity, session 30.10.10.4-0.4-0.3-0.20.4-0.4-0.4-0.3-0.20.2-0.50.4-0.4-0.4-0.5-0.7-0.4-0.3-0.1-0.1-0.30.0
Locomotion distance, session 30.40.40.6-0.8-0.70.50.7-0.7-0.7-0.7-0.60.6-0.80.8-0.8-0.7-0.80.2-0.7-0.7-0.5-0.5-0.50.0
Stereotopy head waving bouts, day 33.33.94.71.92.1-2.0-2.12.12.12.11.9-1.92.1-2.22.22.12.1-1.92.12.11.91.92.00.0
Stereotopy head waving duration, day 30.50.60.90.80.8-0.7-0.80.90.80.90.7-0.70.9-1.01.00.80.9-0.60.90.80.60.60.70.0
Locomotion velocity, session 70.90.91.6-0.9-1.11.11.1-1.0-1.0-1.0-0.90.9-1.01.0-1.0-1.0-1.01.3-0.9-1.0-0.9-0.9-1.00.0
Locomotion distance, session 70.20.21.3-0.5-0.50.70.5-0.4-0.5-0.4-0.50.5-0.40.3-0.3-0.4-0.41.1-0.3-0.5-0.4-0.4-0.40.0
Stereotopy head waving bouts, day 71.41.52.21.51.2-1.0-1.31.31.31.31.2-1.21.4-1.41.41.41.4-1.01.21.41.11.11.20.0
Stereotopy head waving duration, day 70.40.50.60.80.7-0.5-0.70.70.70.70.6-0.60.8-0.80.80.80.8-0.70.60.80.50.50.60.0
Locomotion velocity, session 87.18.59.7-3.0-3.03.03.0-3.0-3.0-3.0-3.13.1-2.93.0-3.0-2.9-2.92.9-2.9-3.1-3.0-3.0-3.00.0
Locomotion distance, session 81.52.22.9-1.7-1.61.51.6-1.6-1.6-1.6-1.41.4-1.61.7-1.7-1.6-1.61.3-1.6-1.7-1.3-1.3-1.40.0
Degree of sensitization distance0.50.52.1-0.6-0.71.00.6-0.6-0.6-0.5-0.90.9-0.50.4-0.4-0.6-0.51.4-0.5-0.7-0.8-0.8-0.80.0
Degree of sensitization stereotypy1.71.92.71.61.4-1.1-1.51.51.51.41.3-1.31.6-1.51.51.51.6-0.91.41.51.11.11.40.0
Conditioned locomotion0.10.20.20.30.4-0.4-0.40.40.40.40.4-0.40.5-0.40.40.40.5-0.20.50.40.40.40.40.0
Cocaine response after cond. corrected2.22.63.31.81.7-1.4-1.81.71.71.71.5-1.51.8-1.81.81.81.8-1.31.61.81.41.41.60.0
Cocaine response after cond. not corrected2.93.54.71.92.0-1.5-2.12.02.02.01.7-1.72.1-2.22.22.12.1-1.21.92.11.61.61.90.0
Cocaine response before conditioning0.30.40.80.50.7-0.4-0.80.70.60.70.4-0.40.6-0.90.90.80.80.10.80.70.30.30.50.0
Saline control response0.10.10.9-0.1-0.10.5-0.0-0.0-0.0-0.0-0.10.10.0-0.10.10.00.10.90.10.0-0.3-0.3-0.00.0
Bone: connectivity density3.14.88.52.22.3-2.7-2.12.22.22.22.2-2.22.1-2.12.12.12.1-2.92.12.22.22.22.30.0
Bone: cortical apparent density5.17.08.02.82.8-2.7-2.82.82.82.72.6-2.62.7-2.72.72.72.8-2.62.72.82.62.62.50.0
Bone: cortical area0.20.30.50.60.5-0.3-0.50.50.50.50.6-0.60.5-0.60.60.60.5-0.20.50.60.50.50.70.0
Bone: cortical porosity0.80.91.41.20.9-0.6-1.01.01.01.01.0-1.01.1-1.01.01.01.0-0.31.01.00.90.91.10.0
Bone: cortical porosity0.70.71.31.10.8-0.4-0.90.90.90.90.8-0.81.0-1.01.00.91.0-0.01.00.90.80.81.00.0
Bone: cortical thickness1.52.43.51.91.7-1.4-1.71.71.71.61.4-1.41.7-1.71.71.71.7-1.31.61.71.31.31.70.0
Bone: cortical thickness4.45.26.22.42.5-2.4-2.42.42.42.42.1-2.12.4-2.42.42.42.4-2.22.42.32.22.22.30.0
Bone: cortical tissue density5.17.08.02.82.8-2.7-2.82.82.82.72.6-2.62.7-2.72.72.72.8-2.72.72.82.62.62.50.0
Condit. Reinf. active minus inactive responses0.60.72.60.90.8-1.3-0.70.70.70.80.8-0.80.6-0.70.70.70.6-1.60.70.71.11.10.60.0
Condit. Reinf. active-inactive response ratio0.80.92.11.00.9-1.3-0.80.90.90.91.0-1.00.8-0.80.80.80.7-1.40.90.91.11.10.80.0
Condit. Reinf. active responses0.80.92.11.11.0-1.2-0.91.00.91.00.9-0.90.9-1.01.00.90.8-1.50.90.91.01.00.80.0
Condit. Reinf. inactive responses0.30.40.90.70.7-0.4-0.80.70.70.70.3-0.30.8-0.90.90.80.8-0.20.70.70.20.20.50.0
Incentive salience index mean1.61.94.11.51.4-1.8-1.31.31.31.41.4-1.41.2-1.31.31.21.1-2.01.31.31.61.61.20.0
Condit. Reinf. lever presses1.31.82.81.51.4-1.6-1.31.31.31.41.4-1.41.3-1.31.31.31.2-1.71.31.31.51.51.30.0
Condit. Reinf. active minus inactive responses0.50.60.90.70.9-0.8-0.90.80.80.80.8-0.80.9-0.80.80.91.0-0.70.80.80.80.80.80.0
Condit. Reinf. active-inactive response ratio0.40.50.70.70.8-0.7-0.70.70.70.70.7-0.70.7-0.60.60.70.7-0.80.60.60.80.80.70.0
Condit. Reinf. active responses0.81.11.40.91.2-1.2-1.11.11.11.11.1-1.11.0-1.01.01.11.2-1.11.11.01.11.11.10.0
Condit. Reinf. inactive responses1.41.92.31.21.4-1.5-1.41.41.31.41.5-1.51.2-1.41.41.41.4-1.21.51.41.51.51.50.0
Condit. Reinf. lever presses0.00.00.10.20.2-0.2-0.20.20.20.10.2-0.20.2-0.10.10.10.2-0.30.10.10.20.20.10.0
Condit. Reinf. lever reinforcers received0.91.21.60.91.2-1.3-1.11.11.11.11.2-1.21.0-1.01.01.11.1-1.31.11.01.21.21.10.0
Conditioned reinforcement - actives0.20.40.80.70.5-0.2-0.60.60.60.50.9-0.90.6-0.70.90.60.60.50.90.90.30.30.80.0
Conditioned reinforcement - inactives0.00.00.20.1-0.0-0.4-0.00.10.0-0.00.3-0.3-0.00.2-0.0-0.0-0.0-0.40.20.00.40.40.00.0
Conditioned locomotion1.11.42.11.51.3-1.0-1.41.21.31.11.2-1.21.3-1.21.21.31.4-0.61.31.31.01.01.30.0
Patch foraging indifference point 0 sec1.42.64.71.51.6-1.7-1.51.61.51.52.2-2.21.5-1.41.31.51.4-1.71.51.52.02.01.60.0
Patch foraging indifference point AUC0.00.00.1-0.10.10.0-0.10.10.10.20.3-0.30.1-0.10.20.00.2-0.1-0.10.00.40.40.20.0
Delay disc. indifference point, 0s delay2.02.22.71.51.5-1.3-1.61.51.51.51.6-1.61.5-1.41.51.61.6-1.11.51.51.61.61.50.0
Delay disc. indifference point, 16s delay0.60.61.10.90.7-0.6-0.80.80.81.00.8-0.80.9-1.00.90.70.8-0.40.90.90.70.70.90.0
Delay disc. indifference point, 2s delay2.12.43.11.71.5-1.4-1.61.71.71.61.7-1.71.7-1.61.31.51.7-1.01.71.81.51.51.70.0
Delay disc. indifference point, 24s delay0.00.00.20.3-0.00.1-0.10.10.20.30.0-0.00.2-0.50.30.10.10.10.10.30.00.00.20.0
Delay disc. indifference point, 4s delay0.90.91.51.20.9-0.8-1.01.01.10.91.1-1.11.1-0.80.60.81.1-0.60.91.00.90.91.10.0
Delay disc. indifference point, 8s delay0.40.40.90.90.4-0.7-0.50.60.70.60.7-0.70.7-0.60.50.50.6-0.50.80.80.60.60.70.0
Indifference point function ln k0.00.00.10.30.1-0.1-0.00.00.0-0.00.1-0.10.1-0.0-0.10.10.0-0.10.10.1-0.2-0.20.10.0
Indifference point function log k0.00.00.10.30.1-0.1-0.00.00.0-0.00.1-0.10.1-0.0-0.10.10.0-0.10.10.1-0.2-0.20.10.0
Patch foraging total patch changes 0 sec1.01.83.81.21.3-1.5-1.21.21.21.21.9-1.91.2-1.01.01.21.1-1.51.21.21.81.81.40.0
Patch foraging total patch changes 12 sec4.45.77.02.42.4-2.3-2.42.42.42.52.6-2.62.4-2.42.52.42.4-2.22.42.42.62.62.30.0
Patch foraging total patch changes 18 sec0.30.50.90.40.6-0.4-0.70.60.60.71.0-1.00.5-0.70.80.60.7-0.50.50.60.90.90.70.0
Patch foraging total patch changes 24 sec1.22.13.11.61.5-1.1-1.61.61.61.61.3-1.31.7-1.71.81.61.7-1.01.41.61.21.21.60.0
Patch foraging total patch changes 6 sec1.52.33.81.31.5-1.6-1.41.41.41.51.9-1.91.3-1.31.31.41.4-1.81.31.42.02.01.50.0
Patch foraging time to switch 0 sec0.00.00.10.00.1-0.3-0.10.10.10.20.1-0.10.1-0.10.10.10.1-0.30.20.10.20.20.10.0
Patch foraging water rate 0 sec0.00.00.20.10.1-0.3-0.10.10.10.00.3-0.30.1-0.0-0.10.10.1-0.50.10.00.20.20.00.0
Patch foraging water rate 12 sec0.20.51.0-0.7-0.70.90.6-0.7-0.7-0.7-0.70.7-0.60.6-0.7-0.6-0.61.0-0.7-0.8-0.9-0.9-0.70.0
Patch foraging water rate 18 sec0.30.51.00.90.8-1.0-0.70.70.70.60.8-0.80.8-0.70.60.80.7-0.90.80.70.40.40.60.0
Patch foraging water rate 24 sec0.20.31.10.50.6-1.0-0.50.50.50.40.6-0.60.4-0.40.30.40.5-1.00.60.50.50.50.30.0
Patch foraging water rate 6 sec0.91.32.81.01.2-1.6-1.11.11.11.21.3-1.31.0-1.21.11.01.1-1.71.11.11.21.20.90.0
Seeking ratio, delayed vs. immediate footshock0.10.10.6-0.5-0.10.50.3-0.3-0.4-0.2-0.20.2-0.50.2-0.1-0.4-0.40.8-0.4-0.6-0.3-0.3-0.40.0
Distance traveled before self-admin0.20.20.6-0.7-0.40.40.5-0.5-0.6-0.50.1-0.1-0.60.6-0.6-0.5-0.60.7-0.4-0.7-0.0-0.0-0.60.0
Distance traveled after self-admin0.91.12.1-1.3-1.30.61.3-1.2-1.3-1.1-0.90.9-1.41.0-1.0-1.3-1.40.5-1.1-1.1-0.8-0.8-1.10.0
Extensor digitorum longus weight8.633.940.7-5.7-6.16.45.9-5.9-5.9-6.0-6.26.2-5.75.8-5.8-5.8-5.96.2-5.9-5.8-6.1-6.1-5.80.0
Bone: elastic displacement0.00.00.10.30.2-0.1-0.30.20.20.20.2-0.20.3-0.20.20.20.4-0.20.20.10.20.20.20.0
Bone: elastic work0.00.10.30.30.1-0.3-0.10.20.20.20.4-0.40.1-0.10.10.00.1-0.50.10.20.40.40.20.0
Bone: endosteal estimation1.94.35.9-2.4-2.32.22.3-2.2-2.2-2.0-1.71.7-2.42.1-2.1-2.2-2.32.2-2.1-2.1-1.8-1.8-1.90.0
Bone: endosteal perimeter1.93.95.3-2.2-2.12.02.2-2.1-2.2-2.1-1.61.6-2.32.1-2.1-2.2-2.32.0-2.0-2.0-1.7-1.7-1.80.0
Epididymis fat weight0.10.30.8-0.6-0.60.70.6-0.6-0.6-0.5-0.50.5-0.70.4-0.4-0.6-0.70.9-0.5-0.5-0.6-0.6-0.60.0
Delta time in closed arm before/after self-admin4.23.97.1-1.9-2.01.71.9-2.0-2.0-2.1-2.72.7-1.92.1-2.1-2.0-1.91.2-2.0-2.2-2.0-2.0-2.10.0
Delta time in open arm before/after self-admin0.00.00.0-0.00.00.1-0.10.10.1-0.00.2-0.20.2-0.00.00.00.10.20.10.1-0.1-0.1-0.00.0
Diff in mean of infusions in LGA sessions0.30.40.8-0.8-0.60.00.8-0.6-0.7-0.5-0.70.7-0.70.6-0.7-0.7-0.9-0.1-0.5-0.6-0.4-0.4-0.70.0
Delay discount exponential model param0.50.61.0-1.0-0.60.80.7-0.8-0.8-0.8-0.80.8-0.90.8-0.6-0.6-0.80.6-0.9-0.9-0.7-0.7-0.80.0
Extinction: sum of active levers before priming0.60.71.0-0.8-1.00.90.9-0.9-0.9-1.0-0.60.6-0.80.9-0.9-0.9-0.91.0-0.8-0.8-0.8-0.8-0.80.0
Active lever presses in extinction session 60.20.21.10.10.3-0.6-0.20.20.20.30.8-0.80.1-0.0-0.10.20.1-0.80.20.11.01.00.20.0
Bone: final force1.01.72.11.31.3-1.1-1.31.31.31.51.3-1.31.2-1.51.51.31.3-0.81.41.41.31.31.40.0
Bone: final moment0.81.31.81.11.1-1.0-1.21.21.21.31.2-1.21.1-1.31.31.21.2-0.71.31.31.21.21.30.0
Food consumed during 24 hour testing period0.81.12.0-0.9-1.11.41.0-1.0-1.0-1.0-1.01.0-1.00.9-0.9-1.0-0.91.4-1.1-0.8-1.1-1.1-1.00.0
Glucose0.50.81.10.90.9-0.3-1.01.01.01.01.0-1.01.0-1.01.01.01.10.10.90.91.01.01.00.0
Heart weight3.14.86.3-2.3-2.32.32.3-2.3-2.3-2.3-1.91.9-2.32.4-2.5-2.3-2.22.1-2.3-2.4-2.0-2.0-2.30.0
Delay discount hyperbolic model param0.50.51.0-1.0-0.50.70.7-0.8-0.8-0.7-0.80.8-0.80.7-0.6-0.5-0.80.5-0.8-0.9-0.6-0.6-0.80.0
Intermittent access intake day 1-15 change0.20.40.7-0.7-0.5-0.20.7-0.6-0.7-0.7-0.60.6-0.70.9-0.5-0.7-0.8-0.4-0.5-0.6-0.5-0.5-0.70.0
Intermittent access intake escalation0.20.40.7-0.7-0.5-0.10.7-0.6-0.7-0.7-0.60.6-0.70.9-0.6-0.7-0.8-0.3-0.5-0.6-0.6-0.6-0.70.0
Intermittent access intake escalation 20.70.81.1-1.0-0.90.41.0-0.9-1.0-1.0-0.90.9-0.91.0-0.8-0.9-1.10.1-0.9-1.0-1.1-1.1-1.00.0
Intermitt. access day 1 inactive lever presses0.20.74.30.40.7-1.7-0.60.60.60.70.5-0.50.5-0.30.40.50.5-2.10.70.41.11.10.50.0
Intermitt. access day 15 inactive lever presses0.71.54.41.11.2-1.6-1.21.11.21.21.0-1.01.3-1.01.01.21.2-2.11.00.91.51.51.10.0
Intermitt. access escalation Index1.21.73.8-0.9-1.21.61.1-1.2-1.1-1.4-1.61.6-1.01.1-1.2-1.1-1.01.6-1.2-0.9-2.0-2.0-1.00.0
Intermittent access day 1 total infusions0.00.00.20.0-0.10.20.1-0.1-0.1-0.10.3-0.3-0.10.1-0.1-0.1-0.10.40.00.10.10.10.00.0
Intermittent access day 15 total infusions0.20.30.7-0.6-0.60.10.7-0.6-0.6-0.7-0.40.4-0.70.8-0.5-0.7-0.80.1-0.4-0.5-0.4-0.4-0.60.0
Intermittent access terminal intake (last 3 days)0.00.00.1-0.2-0.1-0.30.2-0.2-0.2-0.20.1-0.1-0.30.30.0-0.2-0.3-0.3-0.0-0.00.10.1-0.20.0
Intermittent access total infusions0.10.20.3-0.5-0.50.30.5-0.5-0.5-0.5-0.00.0-0.60.6-0.3-0.5-0.60.4-0.4-0.3-0.1-0.1-0.50.0
Intermittent access day 1 locomotion0.10.20.40.40.2-0.1-0.30.30.30.40.6-0.60.3-0.40.30.30.30.20.40.40.60.60.40.0
Intermittent access day 15 total locomotion0.30.60.80.90.8-0.8-0.80.80.80.80.9-0.90.8-0.70.70.80.8-0.50.90.80.80.80.80.0
Intermittent access total locomotion1.01.21.71.21.0-1.0-1.11.11.11.11.3-1.31.1-1.01.01.11.1-0.71.21.11.31.31.10.0
Intermittent access standard deviation0.10.32.20.00.4-1.1-0.10.20.10.30.7-0.70.00.00.20.2-0.1-1.50.20.10.80.80.10.0
Left kidney weight1.04.76.0-2.5-2.21.82.2-2.3-2.3-2.3-2.22.2-2.32.4-2.4-2.3-2.31.3-2.4-2.3-2.1-2.1-2.20.0
Right kidney weight0.10.40.8-0.9-0.60.30.7-0.7-0.7-0.6-0.70.7-0.80.7-0.7-0.7-0.7-0.2-0.8-0.8-0.7-0.7-0.70.0
Cocaine induced anxiety3.24.65.5-2.2-2.31.82.3-2.3-2.3-2.3-2.32.3-2.32.2-2.4-2.3-2.31.3-2.3-2.3-1.8-1.8-2.30.0
Post-drug Anxiety1.11.21.5-1.1-1.20.81.2-1.2-1.2-1.2-0.90.9-1.21.1-1.2-1.2-1.20.6-1.1-1.1-1.1-1.1-1.20.0
Baseline Anxiety3.13.65.62.12.0-1.3-2.12.12.11.92.4-2.42.1-2.02.02.12.2-0.62.12.11.11.12.10.0
Tail length1.24.67.0-2.4-2.31.92.4-2.4-2.4-2.3-1.71.7-2.52.7-2.6-2.3-2.41.4-2.5-2.4-1.3-1.3-2.30.0
Length with tail4.218.122.9-4.7-4.54.04.6-4.6-4.6-4.5-4.04.0-4.74.7-4.8-4.5-4.63.3-4.6-4.6-3.5-3.5-4.40.0
Length without tail3.210.312.5-3.4-3.33.53.3-3.3-3.3-3.3-3.33.3-3.33.3-3.4-3.2-3.33.3-3.4-3.3-3.1-3.1-3.10.0
Times rat made contact with spout1.11.21.61.31.2-1.0-1.21.21.21.11.1-1.11.3-1.21.21.21.3-1.11.01.21.11.11.00.0
Lifetime Intake0.10.10.2-0.4-0.30.10.3-0.3-0.3-0.30.2-0.2-0.50.4-0.2-0.3-0.50.1-0.2-0.20.10.1-0.40.0
Liver weight, left0.10.20.3-0.4-0.50.40.5-0.5-0.5-0.5-0.30.3-0.40.5-0.5-0.5-0.50.3-0.5-0.4-0.6-0.6-0.50.0
Liver weight, right0.40.81.80.70.8-1.1-0.80.80.80.91.1-1.10.7-0.70.80.70.7-1.30.70.91.11.10.80.0
Locomotor activity0.60.91.41.21.0-0.8-1.01.01.01.01.1-1.11.0-1.01.11.01.0-0.71.01.00.80.81.10.0
Locomotor testing distance2.34.15.12.32.2-2.0-2.12.12.12.02.1-2.12.1-2.12.22.12.1-1.62.22.11.71.72.20.0
Locomotor testing rearing4.38.711.52.93.1-3.2-2.92.92.92.93.4-3.42.7-2.72.72.92.8-3.32.92.83.33.33.00.0
Locomotion in novel chamber5.26.68.52.72.8-1.9-2.82.72.72.82.9-2.92.7-2.62.22.82.7-1.82.32.32.92.92.80.0
Locomotion in novel chamber post-restriction0.20.30.80.50.4-0.7-0.40.50.50.50.9-0.90.4-0.40.40.40.4-0.90.50.50.70.70.50.0
Fecal boli incidents, locomotor time 10.10.10.3-0.3-0.40.30.4-0.3-0.3-0.1-0.30.3-0.30.1-0.2-0.4-0.40.1-0.4-0.5-0.1-0.1-0.30.0
Change in fecal boli incidents, locomotor task0.30.30.40.60.4-0.2-0.50.60.60.50.6-0.60.6-0.50.60.50.50.10.70.70.30.30.60.0
Time >=10cm from walls, locomotor time 10.60.71.20.90.8-0.4-0.80.90.80.80.9-0.90.8-0.91.10.90.9-0.10.91.00.80.80.90.0
Bouts of movement, locomotor time 10.60.61.1-0.9-0.80.50.8-0.9-0.9-1.0-0.70.7-0.91.0-0.6-0.8-0.80.2-0.8-0.8-1.0-1.0-0.90.0
Total resting periods, locomotor time 10.80.91.6-1.0-1.00.71.0-1.0-1.0-1.1-0.90.9-1.01.1-0.7-1.0-0.90.5-0.9-0.9-1.3-1.3-1.00.0
Rest time, locomotor task time 10.00.00.4-0.1-0.1-0.20.2-0.2-0.2-0.1-0.10.1-0.20.10.1-0.2-0.2-0.6-0.2-0.1-0.2-0.2-0.10.0
Distance moved, locomotor task time 10.10.10.20.30.30.0-0.20.30.30.30.5-0.50.3-0.30.00.20.20.50.40.30.30.30.30.0
Vertical activity count, locomotor time 10.10.21.1-0.3-0.30.60.3-0.3-0.3-0.4-0.10.1-0.30.3-0.6-0.4-0.31.1-0.2-0.3-0.2-0.2-0.30.0
Time >=10cm from walls, locomotor time 21.31.93.01.61.4-0.3-1.51.51.51.51.7-1.71.5-1.51.41.51.50.61.41.51.31.31.60.0
Bouts of movement, locomotor time 20.10.10.30.20.5-0.6-0.50.30.30.20.1-0.10.2-0.10.00.40.4-0.60.40.20.30.30.20.0
Total resting periods, locomotor time 20.00.00.2-0.10.2-0.4-0.1-0.0-0.0-0.1-0.20.2-0.10.3-0.30.10.1-0.50.1-0.10.00.0-0.10.0
Rest time, locomotor task time 20.91.11.6-1.2-1.20.81.2-1.2-1.1-1.1-1.01.0-1.11.2-1.2-1.1-1.10.5-1.1-1.3-0.8-0.8-1.10.0
Distance moved, locomotor task time 20.00.00.20.20.10.2-0.10.10.10.00.5-0.5-0.00.1-0.30.10.10.30.00.20.30.30.10.0
Vertical activity count, locomotor time 20.10.10.3-0.2-0.30.40.3-0.3-0.3-0.3-0.10.1-0.30.4-0.5-0.3-0.20.6-0.2-0.2-0.2-0.2-0.20.0
Light reinforcement 11.23.06.11.61.7-2.3-1.61.61.61.72.0-2.01.5-1.51.61.51.5-2.51.71.72.02.01.70.0
Light reinforcement 20.61.02.70.80.9-1.4-0.80.90.91.01.1-1.10.9-0.80.90.80.8-1.60.90.81.21.20.90.0
Bone: marrow area1.94.15.6-2.4-2.22.12.2-2.2-2.2-2.0-1.71.7-2.32.1-2.1-2.2-2.22.2-2.0-2.1-1.7-1.7-1.80.0
Bone: maximum diameter0.00.00.1-0.10.00.10.0-0.0-0.10.00.1-0.1-0.2-0.00.00.0-0.10.2-0.0-0.00.00.00.10.0
Bone: maximum force0.00.00.1-0.10.00.0-0.00.00.00.20.1-0.1-0.1-0.20.20.1-0.00.10.10.10.10.10.10.0
Bone: maximum moment0.00.00.1-0.2-0.10.10.1-0.1-0.10.1-0.00.0-0.2-0.10.1-0.1-0.10.20.00.0-0.1-0.10.10.0
Mean time between licks in bursts0.92.32.9-1.7-1.61.51.6-1.6-1.6-1.6-1.51.5-1.51.6-1.6-1.6-1.61.3-1.6-1.6-1.5-1.5-1.40.0
Mean num. licks in bursts0.00.10.40.20.1-0.4-0.10.10.10.10.2-0.20.20.0-0.00.00.1-0.60.10.20.40.40.00.0
Cd content in liver1.41.62.3-1.5-1.41.01.4-1.4-1.4-1.3-1.21.2-1.51.2-1.2-1.3-1.41.0-1.2-1.3-1.3-1.3-1.30.0
Co content in liver2.22.63.0-1.6-1.71.51.7-1.7-1.7-1.6-1.61.6-1.71.6-1.6-1.7-1.61.4-1.7-1.6-1.7-1.7-1.70.0
Cu content in liver0.40.41.2-1.1-0.60.20.8-0.7-0.7-0.6-0.10.1-1.00.8-0.8-0.8-0.9-0.3-0.8-0.80.00.0-0.50.0
Fe content in liver1.72.02.6-1.5-1.61.51.6-1.5-1.5-1.5-1.21.2-1.51.6-1.6-1.6-1.61.4-1.6-1.5-1.0-1.0-1.50.0
K content in liver0.30.30.90.20.5-0.4-0.40.40.40.40.9-0.90.3-0.20.20.40.3-0.60.20.30.80.80.60.0
Mg content in liver0.30.30.70.40.6-0.4-0.50.50.50.50.8-0.80.5-0.40.40.50.5-0.60.40.40.70.70.60.0
Mn content in liver0.30.41.10.20.5-0.7-0.40.40.40.51.0-1.00.3-0.20.20.40.3-0.90.30.41.01.00.70.0
Na content in liver0.20.20.30.30.5-0.3-0.50.50.50.50.5-0.50.5-0.50.50.50.5-0.30.40.40.60.60.50.0
Rb content in liver2.02.34.31.31.4-1.6-1.31.41.41.52.0-2.01.3-1.21.21.41.3-1.71.41.42.12.11.60.0
Se content in liver4.55.37.92.12.4-2.5-2.22.22.22.32.7-2.72.0-2.12.12.22.0-2.72.12.22.82.82.30.0
Sr content in liver0.90.81.3-1.1-1.00.81.0-1.0-1.0-1.0-0.80.8-1.11.0-1.0-1.0-1.00.6-1.0-1.0-0.7-0.7-0.90.0
Zn content in liver2.02.34.61.21.7-1.9-1.51.51.41.51.7-1.71.3-1.31.31.51.4-2.11.41.31.71.71.50.0
Bone: minimum diameter0.50.81.4-1.1-1.11.11.1-1.0-1.0-0.9-0.40.4-1.11.0-1.0-1.0-1.11.2-0.9-0.9-0.5-0.5-0.60.0
Time in familiar zone, hab. session 10.30.30.40.60.7-0.6-0.60.60.60.50.5-0.50.6-0.50.50.60.6-0.50.70.40.50.50.40.0
Time in novel zone, hab. session 10.70.70.90.50.8-0.9-0.90.80.80.90.8-0.80.8-1.01.00.90.9-1.00.80.80.80.80.90.0
Total zone transitions, hab. session 12.13.03.5-1.7-1.81.61.8-1.8-1.8-1.8-1.81.8-1.81.8-1.8-1.8-1.91.3-1.8-1.7-1.7-1.7-1.80.0
Total locomotion distance, hab. session 10.00.10.1-0.1-0.20.10.2-0.2-0.2-0.2-0.30.3-0.20.2-0.2-0.3-0.20.1-0.2-0.2-0.3-0.3-0.40.0
Locomotion velocity, hab. session 10.60.91.1-0.7-1.00.91.0-1.0-1.0-1.0-0.90.9-1.01.0-1.0-1.0-1.00.9-0.9-0.8-1.0-1.0-1.10.0
Time in familiar zone, hab. session 20.50.50.90.60.7-1.0-0.70.70.70.70.8-0.80.6-0.70.70.70.6-0.90.80.60.80.80.70.0
Time in novel zone, hab. session 20.00.00.20.30.2-0.3-0.20.20.20.20.1-0.10.2-0.20.20.20.2-0.40.20.20.20.20.10.0
Total zone transitions, hab. session 20.60.81.0-0.9-1.00.81.0-0.9-0.9-0.9-0.80.8-1.01.0-1.0-1.0-1.00.6-0.9-0.9-0.7-0.7-0.80.0
Total locomotion distance, hab. session 20.10.20.3-0.3-0.50.30.5-0.5-0.5-0.5-0.40.4-0.50.5-0.5-0.5-0.50.2-0.4-0.4-0.5-0.5-0.50.0
Locomotion velocity, hab. session 20.40.50.6-0.6-0.80.60.8-0.7-0.7-0.8-0.70.7-0.70.7-0.7-0.8-0.80.7-0.6-0.6-0.8-0.8-0.70.0
Novel to familiar place preference ratio1.61.72.6-1.4-1.31.61.2-1.3-1.3-1.4-1.41.4-1.21.3-1.3-1.2-1.11.6-1.3-1.2-1.6-1.6-1.30.0
Novelty place preference1.21.32.6-1.1-1.11.50.9-1.0-1.0-1.2-1.31.3-0.91.0-1.0-0.9-0.91.6-1.0-0.9-1.5-1.5-1.10.0
Time in novel zone, NPP test0.40.51.4-0.6-0.61.00.4-0.5-0.5-0.7-0.80.8-0.40.5-0.5-0.4-0.41.2-0.5-0.5-1.1-1.1-0.60.0
Total zone transitions, NPP test0.20.30.6-0.6-0.70.50.7-0.7-0.7-0.6-0.40.4-0.80.7-0.7-0.7-0.80.3-0.7-0.5-0.4-0.4-0.40.0
Total locomotion distance, NPP test0.00.00.20.10.0-0.30.00.10.10.10.2-0.2-0.0-0.00.0-0.0-0.1-0.40.00.20.20.20.20.0
Locomotion velocity, NPP test0.20.30.5-0.6-0.60.40.7-0.6-0.6-0.6-0.40.4-0.70.6-0.6-0.7-0.70.2-0.6-0.5-0.5-0.5-0.50.0
Intraocular pressure2.02.84.4-1.6-1.71.81.6-1.7-1.7-1.9-1.71.7-1.51.7-1.7-1.6-1.52.0-1.5-1.5-2.1-2.1-1.60.0
Delta distance traveled before/after self-admin0.80.81.2-0.8-1.10.71.1-1.0-1.0-0.9-1.11.1-1.10.8-0.7-1.0-1.00.4-0.9-0.8-1.1-1.1-0.80.0
Delta ambulatory time before/after self-admin0.40.51.1-0.5-1.00.40.8-0.7-0.7-0.7-1.01.0-0.80.6-0.5-0.7-0.70.1-0.6-0.4-1.0-1.0-0.60.0
Parametrial fat weight0.30.71.50.60.8-1.2-0.90.80.80.80.7-0.70.7-0.80.70.80.8-1.21.00.80.80.80.60.0
Pavlov. Cond. lever latency2.73.44.8-2.2-1.92.11.8-1.9-1.9-1.9-1.81.8-1.91.8-1.8-1.8-1.72.2-1.9-1.8-1.9-1.9-1.70.0
Pavlov. Cond. magazine entry latency9.812.615.33.93.8-3.8-3.73.73.73.63.6-3.63.7-3.63.63.63.6-3.63.63.63.53.53.50.0
Pavlov. Cond. change in total contacts9.410.012.03.53.4-3.4-3.33.33.33.33.1-3.13.3-3.23.23.33.2-3.43.23.23.13.13.00.0
Pavlov. Cond. index score9.311.714.73.83.6-3.7-3.53.53.53.53.5-3.53.5-3.43.43.53.4-3.53.53.53.53.53.30.0
Pavlov. Cond. latency score7.39.212.13.53.2-3.3-3.13.13.13.13.1-3.13.1-3.03.03.13.0-3.23.13.13.03.02.90.0
Pavlov. Cond. lever contacts3.34.05.62.42.1-2.3-2.02.12.02.02.0-2.02.1-2.02.02.01.9-2.22.02.02.02.01.80.0
Pavlov. Cond. magazine entry number14.217.921.8-4.7-4.54.44.4-4.4-4.4-4.4-4.34.3-4.44.3-4.3-4.4-4.34.2-4.3-4.3-4.2-4.2-4.20.0
Pavlov. Cond. intertrial magazine entries1.31.51.9-1.3-1.41.31.3-1.3-1.3-1.2-1.31.3-1.31.3-1.3-1.3-1.31.2-1.3-1.3-1.1-1.1-1.30.0
Pavlov. Cond. lever-magazine prob. diff.10.813.416.44.13.9-3.9-3.83.83.83.83.7-3.73.8-3.73.73.73.7-3.83.83.73.73.73.50.0
Pavlov. Cond. response bias10.813.416.74.13.8-3.9-3.73.83.83.73.7-3.73.8-3.73.73.73.6-3.83.73.73.73.73.60.0
Pavlov. Cond. lever latency0.30.40.9-0.9-0.70.60.7-0.7-0.7-0.6-0.60.6-0.80.6-0.6-0.6-0.80.6-0.6-0.7-0.5-0.5-0.40.0
Pavlov. Cond. magazine entry latency0.10.10.3-0.0-0.10.40.0-0.1-0.1-0.2-0.40.40.00.1-0.1-0.10.00.5-0.2-0.2-0.5-0.5-0.40.0
Pavlov. Cond. change in total contacts0.40.60.70.80.8-0.8-0.80.80.80.70.8-0.80.9-0.70.70.80.8-0.70.80.80.80.80.60.0
Pavlov. Cond. index score0.10.20.40.60.5-0.3-0.60.50.50.40.3-0.30.6-0.50.50.50.6-0.30.40.40.20.20.20.0
Pavlov. Cond. latency score0.10.10.40.60.4-0.2-0.50.40.50.30.3-0.30.6-0.40.40.40.6-0.10.40.40.10.10.20.0
Pavlov. Cond. lever contacts0.40.61.11.10.8-0.7-0.80.80.90.80.7-0.70.9-0.80.80.80.9-0.70.80.90.70.70.60.0
Pavlov. Cond. magazine entry number0.10.20.4-0.5-0.50.40.6-0.5-0.5-0.4-0.20.2-0.60.5-0.5-0.5-0.60.4-0.4-0.3-0.2-0.2-0.20.0
Pavlov. Cond. intertrial magazine entries1.72.53.3-1.6-1.61.71.6-1.6-1.6-1.6-1.61.6-1.71.5-1.5-1.6-1.61.7-1.6-1.4-1.8-1.8-1.50.0
Pavlov. Cond. lever-magazine prob. diff.0.10.10.20.40.4-0.2-0.40.30.30.20.1-0.10.4-0.30.30.30.5-0.20.20.30.10.10.10.0
Pavlov. Cond. response bias0.81.01.51.21.1-1.0-1.11.11.11.00.9-0.91.2-1.11.11.11.2-1.01.01.10.90.90.80.0
Time in closed arm before self-admin1.82.34.91.21.5-2.0-1.31.41.41.52.0-2.01.2-1.71.61.41.2-2.21.41.61.51.51.40.0
Time in closed arm after self-admin0.30.30.6-0.5-0.50.20.6-0.6-0.6-0.6-0.80.8-0.80.5-0.7-0.5-0.6-0.2-0.6-0.6-0.4-0.4-0.60.0
Time in open arm before self-admin2.22.44.7-1.4-1.72.01.6-1.6-1.6-1.5-1.31.3-1.71.7-1.7-1.6-1.52.2-1.7-1.6-1.2-1.2-1.40.0
Time in open arm after self-admin0.30.41.0-0.7-0.70.90.6-0.6-0.6-0.6-0.30.3-0.40.7-0.6-0.7-0.51.0-0.6-0.7-0.5-0.5-0.70.0
Bone: periosteal estimation0.20.40.9-0.8-0.70.80.7-0.7-0.7-0.6-0.40.4-0.80.6-0.6-0.7-0.70.9-0.6-0.6-0.5-0.5-0.40.0
Bone: periosteal perimeter0.71.21.6-1.2-1.21.21.2-1.2-1.2-1.2-1.01.0-1.31.1-1.1-1.2-1.21.2-1.1-1.1-1.1-1.1-1.00.0
Bone: post-yield work1.01.42.1-1.2-1.21.01.2-1.2-1.2-1.2-1.41.4-1.21.1-1.1-1.2-1.11.0-1.1-1.2-1.4-1.4-1.20.0
Progressive ratio test 1 active lever presses0.20.30.70.50.4-0.3-0.40.50.50.40.9-0.90.4-0.50.80.50.40.10.60.80.60.60.50.0
Progressive ratio test 1 breakpoint0.20.20.60.40.3-0.2-0.40.40.40.40.8-0.80.3-0.50.80.40.30.10.60.70.50.50.40.0
Progressive ratio test 1 inactive lever presses0.00.10.5-0.1-0.1-0.50.0-0.0-0.00.10.3-0.3-0.10.10.0-0.0-0.1-0.70.1-0.00.40.4-0.10.0
Progressive ratio test 2 active lever presses0.50.51.10.70.7-0.5-0.70.70.70.71.0-1.00.7-0.60.90.70.6-0.20.70.71.01.00.70.0
Progressive ratio test 2 breakpoint0.50.61.20.70.7-0.5-0.70.80.80.81.1-1.10.7-0.60.90.80.7-0.20.80.71.11.10.80.0
Progressive ratio test 2 inactive lever presses0.00.10.3-0.1-0.20.00.2-0.2-0.2-0.10.2-0.2-0.20.4-0.3-0.2-0.2-0.1-0.3-0.30.50.5-0.20.0
Incentive Sensitization - Responses0.60.91.60.91.0-0.7-1.01.01.01.01.1-1.11.0-0.81.01.00.9-0.50.90.71.31.30.90.0
Incentive Sensitization - Breakpoint0.60.81.40.80.9-0.7-0.90.90.91.01.0-1.00.9-0.70.90.90.8-0.50.80.61.21.20.90.0
Sum of active levers in priming session hrs 5-60.20.20.70.50.3-0.4-0.30.40.40.40.6-0.60.5-0.20.30.40.3-0.40.40.40.80.80.40.0
Progressive ratio0.00.00.2-0.20.0-0.10.1-0.0-0.10.1-0.00.0-0.2-0.00.2-0.1-0.3-0.1-0.1-0.10.50.5-0.00.0
Food seeking constrained by brief footshock0.50.61.30.60.6-1.0-0.60.70.70.70.9-0.90.6-0.71.00.70.6-1.10.70.90.90.90.70.0
Seeking ratio, punishment vs. effort0.10.20.40.60.3-0.2-0.50.40.50.20.2-0.20.5-0.40.40.50.7-0.30.50.6-0.2-0.20.50.0
Retroperitoneal fat weight0.10.30.60.40.4-0.7-0.40.50.40.70.5-0.50.4-0.60.60.40.4-0.60.60.40.80.80.40.0
Reaction time number correct0.71.43.2-1.0-1.11.51.1-1.1-1.1-1.2-1.31.3-1.11.2-1.2-1.1-1.01.8-1.1-1.0-1.3-1.3-1.10.0
Reaction time mean minus median0.10.20.8-0.2-0.30.40.2-0.4-0.3-0.4-0.90.9-0.30.2-0.1-0.2-0.20.4-0.3-0.2-0.8-0.8-0.40.0
Reaction time mean minus median AUC0.10.20.60.70.5-0.3-0.60.50.50.5-0.10.10.6-0.70.70.70.6-0.10.60.6-0.1-0.10.40.0
Reaction time num false alarms0.50.81.11.00.9-0.7-0.90.90.90.91.0-1.01.0-0.80.90.90.8-0.50.91.00.90.90.90.0
Reaction time num false alarms AUC0.30.50.70.90.7-0.6-0.70.80.70.70.7-0.70.8-0.70.80.80.7-0.40.80.90.60.60.70.0
Reaction time trials correct on left0.71.43.2-1.0-1.11.51.1-1.1-1.1-1.2-1.31.3-1.11.2-1.2-1.1-1.01.8-1.1-1.0-1.3-1.3-1.10.0
Reaction time trials on left0.71.33.0-1.0-1.11.51.0-1.1-1.1-1.2-1.21.2-1.01.1-1.2-1.1-1.01.7-1.1-0.9-1.2-1.2-1.00.0
Reaction time mean0.00.10.40.20.3-0.3-0.30.20.20.2-0.20.20.3-0.30.30.40.3-0.60.10.10.00.00.10.0
Reaction time mean AUC0.00.10.50.10.3-0.4-0.20.10.10.2-0.10.10.2-0.20.20.30.2-0.70.1-0.00.00.00.10.0
Median of all reaction times0.30.41.20.60.8-0.8-0.80.60.70.70.4-0.40.7-0.70.60.80.7-1.10.50.40.60.60.60.0
Reaction time omissions0.20.41.40.50.7-1.0-0.60.60.60.50.2-0.20.4-0.70.70.60.5-1.20.60.70.30.30.40.0
Reaction time false alarm rate1.11.51.91.31.3-1.3-1.21.31.31.31.2-1.21.3-1.31.41.31.2-1.21.31.31.11.11.20.0
Reaction time premature initiation rate0.10.20.50.40.3-0.4-0.30.40.40.60.4-0.40.3-0.70.70.40.3-0.30.50.50.20.20.40.0
Reaction time premature initiations0.10.30.7-0.4-0.60.70.5-0.4-0.5-0.4-0.60.6-0.50.3-0.3-0.5-0.50.8-0.4-0.3-0.7-0.7-0.40.0
Std. dev. reaction times0.00.10.20.10.2-0.2-0.20.10.10.1-0.40.40.1-0.30.30.20.1-0.30.10.1-0.3-0.30.00.0
Reaction time trials completed0.71.33.0-1.0-1.11.51.0-1.1-1.1-1.2-1.21.2-1.01.1-1.2-1.1-1.01.7-1.1-0.9-1.2-1.2-1.00.0
Reaction time trials AUC0.61.23.0-0.8-1.01.50.9-1.0-1.0-1.1-1.21.2-0.91.1-1.1-1.0-0.91.7-1.0-0.9-1.2-1.2-1.00.0
Run reversals in cocaine runway, females1.71.72.9-1.3-1.41.61.3-1.4-1.3-1.3-1.41.4-1.21.2-1.1-1.3-1.31.7-1.3-1.3-1.3-1.3-1.30.0
Run reversals in cocaine runway, males0.30.30.60.70.7-0.3-0.70.60.60.60.5-0.50.7-0.60.50.70.7-0.10.60.40.70.70.70.0
Latency to leave start box in cocaine runway2.22.53.2-1.6-1.61.61.7-1.7-1.7-1.6-1.51.5-1.71.7-1.7-1.7-1.81.6-1.7-1.7-1.3-1.3-1.60.0
Latency to leave start box in cocaine runway, F3.03.46.1-1.8-1.82.21.9-1.9-1.9-1.8-1.81.8-1.81.9-1.9-1.9-1.92.5-1.9-1.8-1.8-1.8-1.70.0
Latency to leave start box in cocaine runway, M0.10.10.9-0.20.0-0.40.2-0.2-0.2-0.10.1-0.1-0.30.4-0.3-0.3-0.4-0.9-0.4-0.40.50.5-0.30.0
Std. dev. time between licks in bursts0.10.20.3-0.5-0.50.40.5-0.5-0.5-0.5-0.40.4-0.40.5-0.5-0.5-0.50.1-0.6-0.5-0.5-0.5-0.40.0
Total sessions with >9 infusions0.00.00.2-0.1-0.0-0.30.1-0.0-0.1-0.00.4-0.4-0.30.10.0-0.1-0.2-0.20.00.10.30.3-0.10.0
Short access day 1 total inactive lever presses0.91.24.31.01.1-1.8-1.01.01.00.91.0-1.00.9-0.80.80.90.9-2.11.11.01.11.10.90.0
Short access day 10 total inactive lever presses0.30.71.1-0.9-0.9-0.00.8-0.8-0.8-0.8-1.11.1-0.81.0-0.9-1.0-0.8-0.6-0.8-1.0-0.5-0.5-1.00.0
Short access day 1 total infusions0.10.10.60.20.3-0.5-0.20.20.20.30.5-0.50.1-0.10.20.20.1-0.60.20.20.80.80.20.0
Short access day 10 total infusions0.20.31.10.40.4-0.5-0.40.40.40.41.1-1.10.3-0.30.50.50.4-0.40.50.50.60.60.40.0
Short access total infusions0.00.10.4-0.10.1-0.20.0-0.0-0.00.00.6-0.6-0.20.10.00.0-0.1-0.2-0.0-0.00.50.5-0.10.0
Short access day 1 locomotion0.81.02.40.81.0-1.3-0.90.90.91.01.0-1.00.7-0.90.80.90.7-1.60.90.91.41.40.90.0
Short access day 10 total locomotion1.73.23.92.01.8-1.7-1.91.81.81.81.9-1.91.8-1.71.71.81.9-1.41.92.01.91.91.90.0
Short access total locomotion0.30.30.90.50.5-0.7-0.50.50.50.50.8-0.80.3-0.40.40.50.4-0.60.50.50.90.90.50.0
One hour access (0.3 mA shock)0.20.21.3-0.3-0.50.60.4-0.4-0.4-0.5-0.30.3-0.40.4-0.1-0.4-0.41.1-0.2-0.1-0.6-0.6-0.30.0
Compulsive drug intake0.10.10.40.30.10.2-0.20.20.20.2-0.00.00.3-0.50.60.10.30.60.30.5-0.0-0.00.30.0
One hour access (shock baseline)0.20.20.6-0.5-0.50.30.5-0.5-0.6-0.6-0.20.2-0.60.8-0.6-0.5-0.60.3-0.4-0.5-0.3-0.3-0.50.0
Social response proportion0.00.00.0-0.1-0.0-0.1-0.00.00.00.10.2-0.20.1-0.10.00.00.0-0.20.0-0.1-0.1-0.1-0.10.0
Social responses0.30.31.50.20.4-1.0-0.30.40.40.41.0-1.00.2-0.20.20.30.2-1.20.30.30.80.80.40.0
Social time0.00.00.0-0.2-0.0-0.10.0-0.0-0.0-0.00.2-0.2-0.10.1-0.0-0.1-0.0-0.2-0.0-0.1-0.1-0.1-0.10.0
Soleus weight0.31.01.71.21.0-0.6-1.21.11.11.10.4-0.41.3-1.31.31.21.2-0.41.11.20.50.50.90.0
Bone: stiffness0.00.00.1-0.1-0.00.1-0.00.0-0.00.10.1-0.1-0.1-0.20.20.10.00.40.10.10.00.00.20.0
Tibialis anterior weight1.34.35.7-1.8-2.12.22.0-2.1-2.0-2.3-2.42.4-1.92.1-2.1-2.0-2.01.9-2.1-2.0-2.3-2.3-2.10.0
Time to tail flick, vehicle, before self-admin0.20.20.80.30.5-0.8-0.40.40.40.30.2-0.20.5-0.50.50.40.4-0.90.50.50.00.00.50.0
Time to tail flick, vehicle, after self-admin0.10.10.20.30.30.0-0.30.30.30.30.3-0.30.3-0.50.40.30.30.10.20.30.00.00.30.0
Time to tail flick, test, before self-admin0.70.71.5-0.7-1.00.90.8-0.8-0.8-0.9-0.90.9-0.80.6-0.6-0.8-0.70.9-0.7-0.6-1.2-1.2-0.70.0
Time to tail flick, test, after self-admin0.20.21.00.40.5-0.7-0.40.40.40.40.4-0.40.3-0.20.30.40.4-1.00.30.40.70.70.30.0
Delta time to tail flick, vehicle, before/after SA0.40.40.60.70.6-0.1-0.60.60.60.70.8-0.80.6-0.70.80.70.70.10.60.60.70.70.60.0
Delta time to tail flick, test, before/after SA2.62.75.01.51.8-1.7-1.71.61.61.71.8-1.81.6-1.31.51.71.6-1.61.51.42.22.21.40.0
Tibia length0.82.13.9-1.2-1.51.91.4-1.4-1.4-1.4-1.61.6-1.31.3-1.3-1.4-1.32.0-1.4-1.4-1.7-1.7-1.30.0
Ambulatory time before self-admin0.30.51.0-1.0-0.70.60.8-0.8-0.8-0.7-0.20.2-0.80.9-1.0-0.8-0.90.6-0.8-1.0-0.2-0.2-0.80.0
Ambulatory time after self-admin2.32.73.9-1.9-1.91.02.0-1.8-1.9-1.7-1.51.5-2.01.7-1.6-1.9-2.00.6-1.7-1.6-1.4-1.4-1.70.0
Bone: tissue strength0.70.71.5-0.7-0.81.00.7-0.7-0.7-0.7-1.21.2-0.60.4-0.4-0.7-0.60.9-0.7-0.7-1.2-1.2-0.90.0
Total heroin consumption0.91.12.20.91.1-1.1-0.91.01.01.21.4-1.40.9-0.90.71.00.8-1.20.80.81.51.50.90.0
Bone: trabecular number5.59.111.43.03.1-3.4-3.03.13.13.13.1-3.13.0-3.03.03.03.0-3.43.03.03.03.03.20.0
Bone: trabecular spacing1.31.73.2-1.1-1.41.61.3-1.3-1.3-1.4-1.31.3-1.21.2-1.2-1.3-1.31.8-1.2-1.2-1.5-1.5-1.30.0
Bone: trabecular thickness0.10.10.60.20.3-0.5-0.20.20.20.2-0.00.00.2-0.30.30.20.2-0.80.10.20.10.10.30.0
Bone: trabecular tissue density0.00.00.0-0.2-0.10.20.1-0.1-0.1-0.0-0.10.1-0.1-0.00.0-0.1-0.20.2-0.1-0.10.00.0-0.20.0
Water consumed over 24 hours0.00.10.3-0.1-0.20.40.1-0.1-0.1-0.1-0.30.3-0.1-0.00.0-0.1-0.00.6-0.1-0.0-0.4-0.4-0.30.0
Number of responses in last shaping day0.10.11.0-0.20.1-0.50.1-0.1-0.10.00.1-0.1-0.20.1-0.1-0.0-0.3-1.0-0.2-0.20.40.4-0.10.0