Best TWAS P = 1.05e-09 · Best GWAS P= 1.05e-09 conditioned to 1.27e-05
| Tissue | Gene | RNA modality | RNA phenotype | h2 | # weights | Model R2 | Model R2 P | TWAS Z | TWAS P | Coloc P | Joint |
|---|---|---|---|---|---|---|---|---|---|---|---|
| BLA | Mtcl1 | mRNA stability | Mtcl1 | 0.07 | 1925 | 0.03 | 8.5e-03 | -5.36 | 8.40e-08 | 0.44 | TRUE |
| LHb | Ptprm | gene expression | Ptprm | 0.59 | 15 | 0.13 | 5.2e-04 | -5.26 | 1.44e-07 | 0.11 | TRUE |
| NAcc | LOC120094772 | intron excision ratio | chr9_113536021_113538070 | 0.04 | 1 | 0.02 | 6.5e-04 | 6.1 | 1.05e-09 | 0.38 | TRUE |
| pVTA | Ptprm | isoform ratio | NM_001168632.1 | 0.07 | 9 | 0.03 | 3.1e-03 | 5.37 | 7.93e-08 | 0.55 | FALSE |