Hub : Genes

Nme6

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose isoform ratio XM_006243850.5 0.03 0.02 3.0e-04 0.02 0.03 0.02 0.03 1.2e-03 3.4e-04 1.2e-03 1.6e-04
2 NAcc isoform ratio NM_001191884.1 0.04 0.02 5.5e-07 0.05 0.04 0.05 0.05 4.0e-08 4.4e-07 5.6e-08 1.4e-07
3 Liver gene expression Nme6 0.28 0.13 0.0e+00 0.29 0.28 0.29 0.28 2.5e-32 8.0e-31 5.7e-32 2.5e-31
4 pVTA gene expression Nme6 0.05 0.04 8.0e-05 0.04 0.04 0.04 0.04 8.0e-04 4.2e-04 4.0e-04 4.3e-04
5 Adipose gene expression Nme6 0.05 0.04 4.9e-04 0.01 0.02 0.02 0.01 7.9e-03 3.9e-03 5.0e-03 7.0e-03
6 Brain gene expression Nme6 0.1 0.06 1.8e-11 0.13 0.12 0.11 0.12 8.3e-12 2.4e-11 3.6e-10 3.2e-11
7 Liver intron excision ratio chr8_118711539_118714950 0.02 0.01 5.6e-03 0.01 0.02 0 0.02 1.2e-02 3.4e-03 7.7e-02 5.3e-03
8 LHb isoform ratio NM_001191884.1 0.17 0.1 3.0e-03 0.04 0.06 0.04 0.04 4.7e-02 1.7e-02 4.7e-02 5.3e-02
9 Liver isoform ratio XM_063266053.1 0.03 0.03 5.1e-03 0.02 0.01 0.01 0.01 3.1e-03 1.3e-02 9.9e-03 1.3e-02
10 pVTA isoform ratio NM_001191884.1 0.03 0.02 6.3e-03 0.02 0.02 0.01 0.01 1.4e-02 1.4e-02 1.0e-01 3.7e-02
11 NAcc isoform ratio XM_006243850.5 0.01 0.01 9.7e-03 0.01 0.01 0.01 0.01 9.7e-03 9.2e-03 2.0e-02 1.9e-02
12 PL gene expression Nme6 0.07 0.04 1.9e-09 0.07 0.08 0.08 0.08 1.2e-08 2.9e-09 4.3e-09 3.5e-09
13 Liver isoform ratio NM_001191884.1 0.02 0.01 7.9e-03 0.01 0.02 0 0.01 1.0e-02 5.5e-03 1.2e-01 1.0e-02
14 OFC gene expression Nme6 0.18 0.12 3.6e-03 0.08 0.06 0.06 0.07 5.9e-03 1.6e-02 1.5e-02 1.1e-02
15 NAcc gene expression Nme6 0.07 0.04 1.7e-14 0.1 0.1 0.1 0.1 1.4e-14 1.6e-14 2.0e-14 2.9e-14
16 Brain intron excision ratio chr8_118711539_118713327 0.02 0.02 8.5e-03 0.02 0.02 0.02 0.02 3.3e-03 4.3e-03 5.2e-03 5.8e-03
17 Adipose mRNA stability Nme6 0.07 0.05 1.0e-03 0.02 0.02 0.02 0.02 1.8e-03 2.5e-03 1.6e-03 3.7e-03
18 PL isoform ratio NM_001191884.1 0.04 0.03 2.0e-04 0.02 0.02 0.02 0.02 1.1e-03 1.8e-03 1.0e-03 3.1e-03
19 IC gene expression Nme6 0.11 0.09 7.1e-03 0.05 0.04 0 0.04 4.1e-03 8.5e-03 2.6e-01 6.4e-03
20 BLA gene expression Nme6 0.07 0.05 5.6e-04 0.04 0.04 0.04 0.04 2.3e-03 4.2e-03 3.0e-03 3.9e-03

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20
Bone: apparent density0.10.10.6-0.0-0.00.10.0-0.30.1-0.1-0.10.1-0.1-0.10.20.2-0.20.1-0.10.6-0.7-0.8-0.8
Area under the delay curve1.41.72.4-1.41.4-1.5-1.4-1.5-1.2-1.41.31.31.2-1.4-1.21.5-1.2-1.2-1.3-0.50.7-1.3-1.3
BMI with tail0.10.40.90.7-0.80.70.80.90.90.7-0.6-0.8-0.60.60.6-0.70.50.40.20.9-0.10.60.6
BMI without tail0.61.93.61.5-1.41.21.51.41.61.4-1.4-1.6-1.41.31.5-1.21.51.21.21.9-1.31.01.0
Body weight4.821.126.24.9-4.94.94.95.14.84.8-4.7-4.7-4.54.74.5-4.84.44.44.14.1-3.44.44.4
Weight adjusted by age0.00.10.20.30.2-0.00.00.30.30.2-0.1-0.3-0.00.30.0-0.30.40.3-0.1-0.20.50.10.1
Bone surface0.10.20.5-0.40.4-0.4-0.4-0.5-0.3-0.50.40.30.4-0.5-0.40.5-0.7-0.5-0.5-0.10.3-0.6-0.6
Bone volume0.10.10.4-0.30.2-0.2-0.3-0.4-0.2-0.30.20.20.2-0.3-0.20.4-0.6-0.3-0.30.2-0.1-0.7-0.7
Breakpoint value in progressive ratio session0.10.10.2-0.30.2-0.4-0.4-0.4-0.3-0.40.30.20.3-0.4-0.20.4-0.3-0.2-0.1-0.10.1-0.2-0.2
Number of licking bursts0.30.41.7-0.50.7-0.7-0.6-0.3-0.6-0.50.60.40.7-0.4-0.70.3-0.6-0.6-0.3-1.31.20.20.2
Context. condit. distance diff. score0.00.00.10.1-0.00.0-0.10.00.00.00.0-0.10.00.0-0.0-0.00.0-0.00.1-0.10.10.20.2
Locomotion velocity, session 10.10.10.3-0.20.0-0.0-0.3-0.2-0.1-0.20.10.20.1-0.2-0.10.2-0.1-0.1-0.30.2-0.1-0.5-0.5
Locomotion distance, session 11.01.33.11.2-1.41.41.11.11.31.1-1.2-1.2-1.21.01.2-0.91.21.10.81.8-1.20.40.4
Locomotion velocity, session 20.30.30.7-0.60.4-0.4-0.6-0.4-0.5-0.50.60.50.6-0.5-0.60.5-0.4-0.6-0.8-0.30.7-0.6-0.6
Locomotion distance, session 20.10.10.6-0.2-0.20.2-0.1-0.10.1-0.10.00.1-0.0-0.20.00.30.0-0.1-0.50.8-0.3-0.7-0.7
Locomotion velocity, session 30.20.21.50.3-0.60.50.40.30.60.3-0.4-0.5-0.40.20.5-0.10.10.20.11.2-0.7-0.3-0.3
Locomotion distance, session 30.91.01.8-1.10.9-0.9-0.9-1.0-0.9-1.11.00.80.9-1.1-0.91.2-1.2-1.2-1.2-0.20.6-1.4-1.4
Stereotopy head waving bouts, day 30.10.20.70.2-0.00.00.10.40.00.2-0.0-0.10.10.3-0.1-0.40.20.10.2-0.80.70.80.8
Stereotopy head waving duration, day 30.20.30.80.5-0.30.40.40.50.30.5-0.4-0.4-0.30.60.3-0.60.60.50.6-0.30.00.90.9
Locomotion velocity, session 70.20.20.90.3-0.30.30.30.10.40.2-0.4-0.3-0.50.20.5-0.10.20.30.20.9-0.9-0.3-0.3
Locomotion distance, session 71.01.32.6-1.21.0-1.1-1.0-1.2-1.1-1.11.01.11.0-1.2-1.01.2-1.2-1.1-1.2-0.40.5-1.6-1.6
Stereotopy head waving bouts, day 70.00.00.10.1-0.00.10.0-0.00.10.0-0.1-0.0-0.10.00.10.00.20.0-0.00.1-0.2-0.1-0.1
Stereotopy head waving duration, day 70.40.50.70.8-0.70.70.70.60.80.7-0.7-0.7-0.70.60.7-0.60.90.60.60.8-0.80.50.5
Locomotion velocity, session 80.30.41.60.5-0.80.80.60.50.80.5-0.6-0.6-0.60.40.6-0.40.60.40.21.3-0.70.10.1
Locomotion distance, session 80.30.42.60.6-0.80.80.50.30.70.4-0.6-0.7-0.60.30.7-0.20.60.30.21.6-1.0-0.2-0.2
Degree of sensitization distance1.01.01.31.1-0.90.91.00.90.91.0-1.0-0.9-1.01.11.0-1.11.01.11.20.6-1.00.90.9
Degree of sensitization stereotypy0.10.10.70.3-0.30.40.30.10.40.2-0.4-0.2-0.40.20.4-0.10.40.30.20.7-0.8-0.2-0.2
Conditioned locomotion3.23.74.8-2.02.0-2.0-1.9-2.1-2.0-2.01.91.91.8-2.0-1.82.1-1.9-1.9-1.8-1.41.2-2.2-2.2
Cocaine response after cond. corrected0.40.52.00.6-0.50.50.50.80.50.6-0.4-0.6-0.30.70.3-0.80.60.40.7-0.40.41.41.4
Cocaine response after cond. not corrected1.82.14.41.6-1.41.41.41.71.41.5-1.3-1.4-1.21.61.2-1.61.41.31.50.6-0.42.12.1
Cocaine response before conditioning1.21.52.71.3-1.41.41.21.11.41.2-1.3-1.2-1.31.11.3-1.11.01.11.11.6-1.30.70.7
Saline control response0.81.02.41.0-1.01.01.00.71.01.0-1.1-0.9-1.10.91.2-0.90.81.21.11.3-1.50.50.5
Bone: connectivity density0.40.62.0-0.70.7-0.7-0.6-1.0-0.6-0.70.50.70.4-0.8-0.40.9-0.7-0.5-0.50.0-0.4-1.4-1.4
Bone: cortical apparent density0.20.20.5-0.50.4-0.4-0.5-0.6-0.4-0.50.40.50.4-0.5-0.40.5-0.4-0.5-0.4-0.20.1-0.7-0.7
Bone: cortical area0.20.31.5-0.50.5-0.5-0.5-0.2-0.5-0.40.60.40.6-0.3-0.70.2-0.4-0.5-0.4-1.11.20.40.4
Bone: cortical porosity0.20.31.0-0.30.5-0.5-0.4-0.8-0.3-0.50.30.30.1-0.5-0.10.6-0.3-0.2-0.10.3-0.7-1.0-1.0
Bone: cortical porosity0.20.20.9-0.30.4-0.4-0.3-0.7-0.4-0.40.20.30.1-0.4-0.10.6-0.3-0.1-0.10.3-0.7-0.9-0.9
Bone: cortical thickness0.20.31.40.3-0.30.30.20.70.30.4-0.2-0.3-0.10.50.0-0.60.30.30.3-0.60.81.21.2
Bone: cortical thickness0.00.00.1-0.10.1-0.1-0.1-0.0-0.2-0.10.10.10.2-0.1-0.20.0-0.2-0.1-0.1-0.40.30.20.2
Bone: cortical tissue density0.20.20.5-0.50.4-0.4-0.5-0.6-0.4-0.50.40.50.4-0.5-0.40.5-0.4-0.5-0.4-0.20.0-0.7-0.7
Condit. Reinf. active minus inactive responses0.10.10.20.2-0.20.10.20.30.20.3-0.2-0.1-0.20.40.1-0.40.40.40.2-0.30.10.40.4
Condit. Reinf. active-inactive response ratio0.20.20.60.4-0.40.40.40.60.40.6-0.4-0.3-0.40.60.3-0.70.50.60.4-0.30.10.80.8
Condit. Reinf. active responses0.00.00.3-0.10.2-0.2-0.1-0.0-0.2-0.10.20.00.2-0.0-0.20.00.0-0.10.0-0.50.40.30.3
Condit. Reinf. inactive responses0.50.61.0-0.70.8-0.8-0.7-0.8-0.9-0.80.80.50.8-0.9-0.70.9-0.7-1.0-0.6-0.50.6-0.6-0.6
Incentive salience index mean0.10.10.2-0.30.2-0.3-0.2-0.1-0.2-0.20.30.20.3-0.2-0.30.1-0.1-0.2-0.3-0.40.5-0.1-0.1
Condit. Reinf. lever presses1.21.62.0-1.41.2-1.3-1.3-1.2-1.3-1.31.31.21.3-1.3-1.31.3-1.4-1.4-1.3-1.01.3-1.1-1.1
Condit. Reinf. active minus inactive responses1.41.82.51.4-1.51.51.51.61.51.5-1.4-1.3-1.31.41.3-1.51.21.31.11.1-1.01.21.2
Condit. Reinf. active-inactive response ratio1.41.62.31.3-1.41.41.31.51.41.4-1.3-1.2-1.21.31.2-1.41.21.21.01.0-0.81.21.2
Condit. Reinf. active responses1.31.72.31.4-1.41.41.41.51.41.4-1.4-1.2-1.31.41.3-1.51.11.41.21.0-1.01.21.2
Condit. Reinf. inactive responses0.10.10.1-0.30.3-0.3-0.3-0.3-0.3-0.20.30.40.3-0.2-0.30.2-0.4-0.2-0.3-0.40.2-0.3-0.3
Condit. Reinf. lever presses1.92.73.41.7-1.81.81.81.81.81.7-1.7-1.6-1.61.71.6-1.71.71.61.41.6-1.31.31.3
Condit. Reinf. lever reinforcers received1.62.22.81.5-1.61.61.61.71.61.6-1.5-1.4-1.51.61.5-1.61.31.51.31.2-1.21.41.4
Conditioned reinforcement - actives1.83.04.4-1.92.1-1.9-1.8-1.7-1.6-1.81.81.81.8-1.7-1.81.7-1.7-1.8-1.7-1.71.8-1.2-1.2
Conditioned reinforcement - inactives2.33.36.5-1.91.7-1.7-1.7-1.4-1.8-1.71.92.02.0-1.6-2.01.5-1.8-1.8-2.0-2.52.5-1.0-1.0
Conditioned locomotion0.30.40.8-0.70.8-0.7-0.6-0.8-0.6-0.70.60.70.5-0.7-0.50.8-0.6-0.7-0.8-0.20.2-0.9-0.9
Patch foraging indifference point 0 sec1.22.23.71.6-1.51.51.41.21.51.4-1.6-1.5-1.61.41.6-1.31.51.61.41.7-1.90.80.8
Patch foraging indifference point AUC0.10.10.60.1-0.30.10.2-0.10.20.1-0.2-0.2-0.20.00.30.10.20.20.10.8-0.7-0.2-0.2
Delay disc. indifference point, 0s delay0.00.00.00.1-0.0-0.0-0.0-0.10.0-0.0-0.0-0.0-0.0-0.00.00.10.1-0.10.10.1-0.10.10.1
Delay disc. indifference point, 16s delay0.80.91.4-1.01.0-1.0-1.0-1.1-1.0-1.00.90.90.9-1.0-0.91.1-0.9-0.9-1.2-0.50.5-1.0-1.0
Delay disc. indifference point, 2s delay0.20.20.5-0.50.6-0.6-0.5-0.5-0.4-0.50.50.40.4-0.5-0.40.5-0.4-0.3-0.4-0.20.3-0.7-0.7
Delay disc. indifference point, 24s delay0.91.01.3-1.01.1-1.1-1.0-1.1-1.0-1.11.01.00.9-1.1-0.91.1-1.0-0.9-1.1-0.50.6-1.1-1.1
Delay disc. indifference point, 4s delay1.41.52.1-1.31.3-1.4-1.4-1.3-1.1-1.31.31.11.2-1.3-1.21.3-1.2-1.1-1.1-0.91.1-1.0-1.0
Delay disc. indifference point, 8s delay1.72.02.7-1.51.5-1.5-1.5-1.6-1.3-1.51.41.51.3-1.5-1.31.6-1.4-1.3-1.4-0.70.8-1.4-1.4
Indifference point function ln k0.30.50.9-0.70.6-0.3-0.6-0.5-0.6-0.60.60.60.7-0.7-0.70.7-0.7-0.9-1.0-0.40.8-0.9-0.9
Indifference point function log k0.30.50.9-0.70.6-0.3-0.6-0.5-0.6-0.60.60.60.7-0.7-0.70.7-0.7-0.9-1.0-0.40.8-0.9-0.9
Patch foraging total patch changes 0 sec1.22.33.31.7-1.61.51.51.31.61.5-1.6-1.5-1.61.51.7-1.41.51.71.51.6-1.81.01.0
Patch foraging total patch changes 12 sec1.01.31.61.2-1.21.21.21.11.01.2-1.2-1.1-1.21.21.2-1.11.11.21.11.0-1.20.90.9
Patch foraging total patch changes 18 sec1.72.64.61.6-1.71.61.61.31.61.6-1.7-1.5-1.81.61.7-1.51.61.91.61.7-2.21.21.2
Patch foraging total patch changes 24 sec1.93.24.21.9-2.01.91.91.92.01.9-1.9-1.6-1.91.91.8-1.91.81.91.61.7-1.81.31.3
Patch foraging total patch changes 6 sec0.30.41.80.6-0.60.40.60.30.70.5-0.7-0.5-0.80.50.8-0.40.70.70.41.1-1.3-0.2-0.2
Patch foraging time to switch 0 sec0.20.41.3-0.50.7-0.7-0.5-0.4-0.6-0.50.60.60.6-0.4-0.70.3-0.5-0.6-0.4-1.11.0-0.1-0.1
Patch foraging water rate 0 sec0.20.30.70.6-0.50.50.50.50.50.6-0.5-0.5-0.50.60.5-0.60.50.60.60.4-0.50.80.8
Patch foraging water rate 12 sec0.10.30.50.6-0.60.70.60.60.50.6-0.6-0.5-0.50.50.5-0.50.60.40.30.5-0.50.60.6
Patch foraging water rate 18 sec0.10.10.50.3-0.20.10.30.50.30.3-0.2-0.3-0.10.30.1-0.40.2-0.00.2-0.00.30.70.7
Patch foraging water rate 24 sec0.81.11.91.1-0.90.81.11.11.01.1-1.0-1.1-1.01.11.0-1.11.10.91.20.7-0.71.41.4
Patch foraging water rate 6 sec0.40.50.80.7-0.70.80.80.70.60.7-0.7-0.7-0.80.70.7-0.70.60.60.80.9-0.80.70.7
Seeking ratio, delayed vs. immediate footshock1.92.33.4-1.51.8-1.8-1.6-1.8-1.6-1.71.51.21.5-1.7-1.41.7-1.5-1.7-1.2-0.90.9-1.6-1.6
Distance traveled before self-admin0.40.61.4-0.80.6-0.8-0.8-0.5-0.8-0.60.80.70.8-0.6-0.90.5-0.8-0.7-0.8-1.21.2-0.3-0.3
Distance traveled after self-admin0.30.30.6-0.60.5-0.7-0.7-0.5-0.7-0.50.60.60.6-0.5-0.70.5-0.6-0.5-0.4-0.70.8-0.2-0.2
Extensor digitorum longus weight0.10.51.2-0.70.7-0.7-0.7-0.5-0.7-0.60.70.70.8-0.6-0.80.6-1.1-0.7-0.7-1.01.1-0.2-0.2
Bone: elastic displacement0.10.10.40.2-0.20.20.20.30.10.3-0.2-0.1-0.10.30.1-0.40.10.30.2-0.30.20.60.6
Bone: elastic work0.40.51.10.7-0.60.70.70.90.70.7-0.6-0.7-0.50.70.5-0.80.60.50.60.2-0.01.11.1
Bone: endosteal estimation0.00.10.40.3-0.10.10.1-0.10.10.1-0.2-0.3-0.30.10.3-0.00.20.20.30.5-0.7-0.2-0.2
Bone: endosteal perimeter1.02.22.6-1.61.5-1.5-1.5-1.6-1.5-1.61.51.41.5-1.6-1.51.6-1.3-1.5-1.5-1.11.2-1.5-1.5
Epididymis fat weight0.30.91.31.0-0.80.91.11.10.91.0-1.0-0.9-0.91.00.9-1.00.90.80.80.7-0.71.11.1
Delta time in closed arm before/after self-admin0.60.50.9-0.80.6-0.5-0.7-0.8-1.0-0.70.70.70.7-0.8-0.70.8-0.9-0.8-0.8-0.50.3-0.9-0.9
Delta time in open arm before/after self-admin0.30.30.40.6-0.40.40.60.50.50.5-0.5-0.6-0.50.50.5-0.50.60.60.60.4-0.30.60.6
Diff in mean of infusions in LGA sessions0.20.20.80.3-0.40.10.10.50.30.3-0.1-0.3-0.00.4-0.0-0.50.30.20.5-0.70.70.90.9
Delay discount exponential model param1.61.82.61.4-1.51.51.51.61.31.5-1.3-1.3-1.31.51.2-1.61.31.21.40.6-0.81.41.4
Extinction: sum of active levers before priming0.00.10.2-0.10.3-0.4-0.3-0.4-0.1-0.30.20.00.1-0.3-0.10.3-0.1-0.2-0.00.2-0.3-0.1-0.1
Active lever presses in extinction session 60.10.10.60.3-0.60.40.10.00.40.2-0.3-0.2-0.30.10.4-0.10.30.40.00.8-0.6-0.3-0.3
Bone: final force1.22.03.51.6-1.41.41.31.61.41.4-1.3-1.5-1.21.51.2-1.61.51.31.40.7-0.51.91.9
Bone: final moment1.42.34.11.6-1.51.51.41.81.51.6-1.4-1.6-1.31.61.3-1.71.61.41.40.8-0.52.02.0
Food consumed during 24 hour testing period1.31.82.21.4-1.41.41.41.51.41.4-1.4-1.3-1.41.41.3-1.41.41.41.21.2-1.11.31.3
Glucose1.01.52.61.3-1.31.31.41.11.21.2-1.3-1.2-1.31.11.3-1.11.01.21.21.6-1.50.80.8
Heart weight1.82.75.81.6-1.71.71.62.01.61.7-1.5-1.5-1.31.81.3-1.91.71.51.50.5-0.32.42.4
Delay discount hyperbolic model param1.82.12.81.5-1.61.61.61.71.31.6-1.4-1.4-1.41.61.3-1.61.41.31.40.7-0.91.41.4
Intermittent access intake day 1-15 change0.91.83.3-1.41.4-1.3-1.3-1.1-1.3-1.21.41.41.4-1.2-1.41.1-1.3-1.3-1.8-1.71.7-1.1-1.1
Intermittent access intake escalation1.22.54.1-1.61.6-1.5-1.5-1.3-1.5-1.41.61.61.6-1.4-1.71.3-1.5-1.6-2.0-1.92.0-1.2-1.2
Intermittent access intake escalation 20.50.51.8-0.70.7-0.5-0.5-0.3-0.7-0.50.70.80.8-0.5-0.80.3-0.7-0.7-1.2-1.31.2-0.3-0.3
Intermitt. access day 1 inactive lever presses0.00.10.6-0.20.4-0.3-0.2-0.0-0.3-0.20.30.30.3-0.1-0.40.1-0.2-0.1-0.3-0.60.80.20.2
Intermitt. access day 15 inactive lever presses0.91.94.3-1.41.3-1.4-1.5-1.1-1.3-1.31.51.41.5-1.2-1.61.2-1.3-1.2-1.5-1.82.1-0.6-0.6
Intermitt. access escalation Index0.10.10.4-0.0-0.0-0.1-0.1-0.3-0.0-0.1-0.0-0.0-0.1-0.20.10.3-0.00.1-0.00.6-0.5-0.7-0.7
Intermittent access day 1 total infusions0.30.40.7-0.60.8-0.7-0.8-0.7-0.4-0.70.70.60.7-0.7-0.70.7-0.5-0.7-0.7-0.70.8-0.4-0.4
Intermittent access day 15 total infusions1.82.74.3-1.71.8-1.6-1.7-1.5-1.4-1.61.71.61.7-1.5-1.71.5-1.5-1.6-2.1-1.92.0-1.3-1.3
Intermittent access terminal intake (last 3 days)1.41.83.0-1.31.5-1.4-1.5-1.3-1.0-1.31.41.21.4-1.3-1.41.3-1.2-1.3-1.7-1.41.5-1.2-1.2
Intermittent access total infusions1.92.33.3-1.51.7-1.6-1.7-1.4-1.2-1.51.61.41.6-1.4-1.61.4-1.3-1.5-1.8-1.61.8-1.1-1.1
Intermittent access day 1 locomotion0.00.10.20.3-0.10.20.10.10.40.2-0.2-0.3-0.30.20.3-0.10.40.20.10.4-0.30.00.0
Intermittent access day 15 total locomotion0.61.01.9-1.11.1-0.8-0.9-1.0-0.8-0.90.91.00.9-1.0-0.91.0-0.9-1.0-1.4-0.80.7-1.3-1.3
Intermittent access total locomotion1.21.42.4-1.21.3-1.0-1.2-1.2-1.0-1.21.11.11.1-1.2-1.01.2-1.0-1.2-1.5-0.80.8-1.6-1.6
Intermittent access standard deviation0.10.21.4-0.00.2-0.1-0.10.30.10.00.20.10.30.1-0.4-0.30.0-0.2-0.8-1.11.20.40.4
Left kidney weight0.73.14.12.0-2.01.91.91.91.91.8-1.8-1.9-1.81.81.8-1.81.61.61.51.8-1.51.51.5
Right kidney weight0.31.41.81.3-1.31.21.21.21.31.2-1.2-1.2-1.21.21.3-1.11.01.10.91.4-1.21.01.0
Cocaine induced anxiety0.30.40.70.8-0.40.40.40.60.70.5-0.5-0.8-0.50.60.5-0.60.80.70.80.40.00.80.8
Post-drug Anxiety0.00.00.20.30.0-0.00.10.10.30.1-0.1-0.4-0.10.20.1-0.20.30.20.40.10.10.30.3
Baseline Anxiety0.30.40.6-0.70.6-0.5-0.5-0.7-0.7-0.60.50.70.5-0.7-0.50.7-0.7-0.7-0.5-0.30.1-0.8-0.8
Tail length4.818.622.14.7-4.34.44.44.34.44.4-4.4-4.4-4.44.44.4-4.44.44.44.33.8-4.04.04.0
Length with tail8.537.043.06.5-6.36.46.36.66.16.4-6.2-6.1-6.06.46.0-6.56.06.15.84.8-4.76.26.2
Length without tail6.721.427.04.9-4.95.14.85.24.64.9-4.7-4.5-4.54.94.4-5.04.44.54.23.5-3.34.94.9
Times rat made contact with spout0.70.81.00.9-0.90.90.91.00.90.9-0.9-0.8-0.81.00.8-1.00.90.90.90.5-0.61.01.0
Lifetime Intake2.32.84.4-1.71.8-1.6-1.8-1.6-1.5-1.71.71.61.7-1.6-1.71.6-1.5-1.7-2.1-1.61.6-1.5-1.5
Liver weight, left0.61.11.51.1-1.11.11.10.91.11.0-1.1-1.0-1.11.01.1-1.00.81.11.11.1-1.20.80.8
Liver weight, right1.62.83.31.8-1.71.71.71.51.71.6-1.7-1.7-1.71.61.8-1.51.71.71.81.8-1.81.41.4
Locomotor activity5.48.510.23.2-3.13.12.92.93.03.0-3.0-3.0-3.03.02.9-3.03.12.92.92.6-2.52.62.6
Locomotor testing distance3.76.88.12.8-2.72.82.62.72.72.7-2.7-2.7-2.62.72.6-2.72.72.52.52.2-2.12.42.4
Locomotor testing rearing0.00.00.00.1-0.10.2-0.00.10.10.1-0.10.0-0.10.20.1-0.20.00.20.2-0.20.00.20.2
Locomotion in novel chamber0.10.10.5-0.20.2-0.2-0.4-0.1-0.4-0.20.30.30.4-0.2-0.40.1-0.2-0.4-0.6-0.60.7-0.1-0.1
Locomotion in novel chamber post-restriction0.30.51.30.7-1.00.90.80.60.50.7-0.8-0.6-0.80.60.8-0.60.60.50.30.9-1.10.40.4
Fecal boli incidents, locomotor time 10.40.61.31.0-0.60.70.70.80.80.7-0.7-1.1-0.70.80.7-0.80.80.51.00.3-0.31.11.1
Change in fecal boli incidents, locomotor task0.10.10.4-0.40.2-0.2-0.2-0.2-0.2-0.20.20.70.2-0.3-0.20.3-0.3-0.0-0.20.1-0.1-0.4-0.4
Time >=10cm from walls, locomotor time 10.30.30.9-0.60.3-0.2-0.4-0.6-0.7-0.50.40.50.3-0.6-0.40.6-0.6-0.6-0.7-0.1-0.1-0.9-0.9
Bouts of movement, locomotor time 10.10.10.40.3-0.20.10.30.30.30.3-0.2-0.4-0.20.30.3-0.30.20.40.60.2-0.00.30.3
Total resting periods, locomotor time 10.00.00.20.2-0.20.10.20.20.20.2-0.2-0.3-0.20.20.2-0.20.10.30.40.2-0.00.20.2
Rest time, locomotor task time 10.50.71.0-0.90.8-0.7-0.8-0.9-1.0-0.90.90.80.8-0.9-0.80.9-1.0-0.9-0.4-0.70.6-0.4-0.4
Distance moved, locomotor task time 11.01.42.11.3-1.31.31.31.51.11.4-1.2-1.1-1.21.41.1-1.41.31.21.00.7-0.91.01.0
Vertical activity count, locomotor time 10.51.21.61.2-1.11.01.21.20.91.1-1.1-1.3-1.11.11.1-1.21.01.01.20.8-0.91.11.1
Time >=10cm from walls, locomotor time 20.91.32.01.2-1.31.41.21.21.01.2-1.2-1.2-1.21.21.2-1.21.01.00.90.9-1.11.21.2
Bouts of movement, locomotor time 20.10.10.3-0.30.3-0.2-0.2-0.0-0.0-0.10.20.60.3-0.1-0.30.1-0.1-0.2-0.3-0.50.5-0.2-0.2
Total resting periods, locomotor time 20.10.20.7-0.50.6-0.5-0.5-0.3-0.3-0.40.50.80.5-0.4-0.50.3-0.3-0.4-0.5-0.60.6-0.4-0.4
Rest time, locomotor task time 20.00.10.1-0.20.3-0.3-0.3-0.4-0.3-0.30.3-0.00.2-0.3-0.20.3-0.3-0.20.2-0.00.10.20.2
Distance moved, locomotor task time 20.81.01.61.0-1.21.21.11.31.01.2-1.1-0.7-1.01.21.0-1.21.01.00.40.6-0.80.50.5
Vertical activity count, locomotor time 20.00.10.10.2-0.30.30.40.30.10.3-0.3-0.2-0.30.30.2-0.30.20.1-0.10.1-0.2-0.2-0.2
Light reinforcement 10.51.21.81.2-0.91.11.11.11.21.1-1.1-1.3-1.11.11.1-1.11.21.00.91.0-0.91.01.0
Light reinforcement 20.10.20.6-0.20.3-0.2-0.2-0.4-0.2-0.40.20.00.2-0.4-0.10.5-0.4-0.5-0.40.5-0.2-0.8-0.8
Bone: marrow area0.00.10.50.3-0.10.10.2-0.00.10.1-0.2-0.3-0.30.10.3-0.00.30.20.40.5-0.7-0.1-0.1
Bone: maximum diameter0.30.61.7-0.80.8-0.8-0.8-0.6-0.8-0.70.90.70.9-0.7-0.90.6-0.6-0.8-0.7-1.21.3-0.1-0.1
Bone: maximum force0.71.31.91.3-1.11.11.11.21.11.1-1.1-1.3-1.01.21.0-1.21.11.11.20.8-0.71.41.4
Bone: maximum moment0.81.42.21.3-1.11.11.11.31.21.2-1.1-1.3-1.11.21.1-1.21.21.11.10.8-0.61.51.5
Mean time between licks in bursts0.82.02.4-1.61.4-1.4-1.5-1.4-1.4-1.41.41.51.4-1.4-1.41.4-1.4-1.4-1.6-1.31.3-1.4-1.4
Mean num. licks in bursts0.81.22.81.1-1.21.21.10.81.11.0-1.2-0.9-1.20.91.2-0.81.11.10.91.7-1.60.30.3
Cd content in liver0.10.10.4-0.30.2-0.2-0.3-0.4-0.2-0.30.20.30.2-0.4-0.20.4-0.1-0.3-0.40.1-0.2-0.7-0.7
Co content in liver1.61.82.7-1.51.4-1.4-1.4-1.2-1.4-1.31.41.51.4-1.3-1.51.2-0.9-1.2-1.5-1.61.5-1.0-1.0
Cu content in liver4.25.06.12.4-2.22.22.32.22.12.2-2.2-2.4-2.22.22.2-2.22.42.12.51.9-1.92.32.3
Fe content in liver1.11.42.11.2-1.01.01.11.21.11.2-1.1-1.0-1.11.31.0-1.31.41.31.40.4-0.71.41.4
K content in liver0.30.30.80.6-0.50.50.60.50.60.5-0.5-0.8-0.50.40.5-0.40.90.30.50.8-0.40.50.5
Mg content in liver0.70.71.5-0.90.8-0.8-0.8-0.9-0.8-1.00.90.60.9-1.0-0.91.0-0.2-1.2-0.8-0.30.9-0.8-0.8
Mn content in liver0.10.10.90.1-0.30.30.2-0.00.30.0-0.2-0.2-0.2-0.10.30.10.6-0.1-0.20.9-0.6-0.5-0.5
Na content in liver0.60.61.50.8-0.60.60.70.60.70.7-0.8-0.7-0.80.80.8-0.71.20.90.90.6-1.00.70.7
Rb content in liver0.50.51.40.7-0.40.40.50.60.40.7-0.6-0.5-0.60.80.5-0.90.61.01.1-0.4-0.41.21.2
Se content in liver0.10.10.30.3-0.40.40.30.40.40.3-0.3-0.3-0.30.20.3-0.20.50.10.20.5-0.10.10.1
Sr content in liver0.10.10.6-0.1-0.30.30.10.00.2-0.10.0-0.10.0-0.20.00.20.2-0.4-0.50.8-0.0-0.6-0.6
Zn content in liver2.32.63.61.8-1.61.61.71.51.61.6-1.6-1.8-1.61.51.7-1.51.91.41.61.7-1.61.51.5
Bone: minimum diameter0.61.11.2-1.11.1-1.1-1.1-1.0-1.1-1.11.11.01.1-1.1-1.11.1-1.0-1.1-1.0-1.01.0-0.9-0.9
Time in familiar zone, hab. session 11.81.73.3-1.41.5-1.5-1.3-1.3-1.5-1.31.41.41.4-1.2-1.41.1-1.3-1.2-1.0-1.81.4-0.8-0.8
Time in novel zone, hab. session 10.90.91.11.0-1.01.11.01.01.01.0-1.0-1.0-1.00.91.0-0.91.00.90.81.0-0.90.70.7
Total zone transitions, hab. session 10.70.92.90.9-1.21.20.90.91.20.9-1.0-0.9-1.00.81.0-0.71.10.90.41.7-1.20.10.1
Total locomotion distance, hab. session 10.30.51.20.7-0.80.80.70.70.80.7-0.7-0.7-0.70.60.8-0.60.70.60.51.1-0.80.30.3
Locomotion velocity, hab. session 10.40.61.70.7-0.90.90.80.70.90.7-0.8-0.8-0.80.60.8-0.60.70.70.61.3-1.00.20.2
Time in familiar zone, hab. session 20.80.82.0-0.91.0-1.0-0.9-0.7-0.9-0.81.00.71.0-0.8-1.00.7-0.7-0.9-0.6-1.41.3-0.1-0.1
Time in novel zone, hab. session 20.10.10.40.2-0.20.30.20.00.20.2-0.3-0.1-0.30.10.3-0.10.10.30.00.5-0.6-0.3-0.3
Total zone transitions, hab. session 20.10.20.70.4-0.60.60.40.50.50.3-0.4-0.5-0.30.30.4-0.30.40.2-0.10.9-0.20.00.0
Total locomotion distance, hab. session 20.50.61.40.8-0.90.90.80.80.80.7-0.8-0.9-0.80.70.8-0.60.70.70.61.2-0.80.50.5
Locomotion velocity, hab. session 20.40.51.40.7-0.80.80.70.70.80.7-0.7-0.8-0.70.60.8-0.60.70.60.51.2-0.80.40.4
Novel to familiar place preference ratio0.90.94.01.0-0.80.80.90.30.90.7-1.0-0.9-1.10.61.2-0.40.90.80.91.8-2.0-0.2-0.2
Novelty place preference0.91.04.41.0-0.70.80.90.30.80.7-1.0-0.9-1.10.61.2-0.40.90.80.91.9-2.1-0.3-0.3
Time in novel zone, NPP test1.01.14.41.1-0.80.81.00.40.90.8-1.1-1.0-1.20.71.3-0.51.00.91.11.8-2.1-0.1-0.1
Total zone transitions, NPP test2.84.09.02.1-2.32.32.01.92.31.9-2.0-2.1-2.11.82.1-1.72.11.71.43.0-2.11.11.1
Total locomotion distance, NPP test1.41.93.11.4-1.51.51.41.41.51.3-1.4-1.5-1.41.31.4-1.21.41.21.11.8-1.31.01.0
Locomotion velocity, NPP test1.52.13.91.5-1.61.61.51.41.61.4-1.5-1.6-1.51.31.5-1.31.51.31.22.0-1.51.01.0
Intraocular pressure0.81.22.31.1-0.90.91.10.80.81.0-1.1-1.0-1.21.11.2-1.01.01.21.50.8-1.51.11.1
Delta distance traveled before/after self-admin0.10.10.50.4-0.20.20.20.20.40.2-0.3-0.3-0.30.20.4-0.20.40.40.40.7-0.50.20.2
Delta ambulatory time before/after self-admin0.91.11.91.2-1.01.00.90.91.11.0-1.1-1.1-1.11.01.1-0.91.11.21.21.4-1.20.90.9
Parametrial fat weight0.92.02.81.5-1.41.61.71.71.41.6-1.5-1.5-1.51.51.5-1.51.41.31.21.3-1.11.01.0
Pavlov. Cond. lever latency4.25.26.52.5-2.32.32.22.12.32.3-2.4-2.2-2.42.32.4-2.32.42.52.42.0-2.42.02.0
Pavlov. Cond. magazine entry latency7.39.410.8-3.33.2-3.1-3.1-2.9-3.2-3.13.23.03.2-3.1-3.23.0-3.1-3.2-3.1-3.03.2-2.5-2.5
Pavlov. Cond. change in total contacts1.71.82.7-1.51.4-1.4-1.4-1.2-1.4-1.31.41.41.4-1.3-1.51.2-1.3-1.3-1.3-1.61.5-0.9-0.9
Pavlov. Cond. index score6.27.89.4-3.02.9-2.9-2.8-2.6-2.9-2.82.92.83.0-2.8-3.02.7-2.9-2.9-2.8-2.93.1-2.2-2.2
Pavlov. Cond. latency score6.17.79.1-3.02.8-2.8-2.8-2.6-2.8-2.82.92.72.9-2.8-2.92.7-2.8-2.9-2.8-2.72.9-2.3-2.3
Pavlov. Cond. lever contacts2.32.73.5-1.81.6-1.6-1.6-1.5-1.6-1.61.71.61.7-1.7-1.71.6-1.8-1.8-1.8-1.51.9-1.4-1.4
Pavlov. Cond. magazine entry number7.59.511.03.3-3.23.23.22.93.23.1-3.2-3.1-3.23.13.2-3.03.13.13.13.2-3.22.42.4
Pavlov. Cond. intertrial magazine entries0.30.40.60.6-0.50.50.60.50.60.6-0.6-0.6-0.60.60.6-0.60.70.60.80.6-0.70.60.6
Pavlov. Cond. lever-magazine prob. diff.5.56.89.0-2.82.6-2.7-2.6-2.4-2.7-2.62.72.62.8-2.6-2.82.5-2.7-2.7-2.6-2.83.0-1.9-1.9
Pavlov. Cond. response bias6.58.19.9-3.12.9-2.9-2.9-2.6-2.9-2.83.02.83.0-2.8-3.02.7-2.9-3.0-2.9-2.93.1-2.2-2.2
Pavlov. Cond. lever latency0.50.70.9-0.91.0-1.0-0.8-0.9-0.9-0.80.80.80.8-0.8-0.80.8-0.8-0.7-0.6-0.90.7-0.6-0.6
Pavlov. Cond. magazine entry latency0.10.20.4-0.40.3-0.3-0.4-0.3-0.3-0.40.40.30.4-0.4-0.40.4-0.3-0.6-0.5-0.20.6-0.4-0.4
Pavlov. Cond. change in total contacts1.93.03.81.9-1.91.91.81.91.81.8-1.7-1.7-1.71.81.7-1.82.01.71.51.5-1.21.61.6
Pavlov. Cond. index score0.10.20.30.5-0.50.50.40.60.40.4-0.4-0.4-0.40.40.4-0.40.50.20.30.5-0.10.40.4
Pavlov. Cond. latency score0.10.10.20.3-0.40.40.30.40.30.3-0.3-0.3-0.20.30.2-0.30.40.10.10.40.00.20.2
Pavlov. Cond. lever contacts0.71.01.41.1-1.21.21.01.11.11.0-1.1-1.0-1.01.01.1-1.01.01.00.81.2-1.00.70.7
Pavlov. Cond. magazine entry number0.20.20.40.5-0.40.40.50.40.50.5-0.5-0.4-0.50.50.5-0.50.40.60.50.3-0.60.40.4
Pavlov. Cond. intertrial magazine entries0.60.91.6-1.11.1-1.1-1.0-1.0-1.0-0.91.01.21.0-0.9-1.00.8-1.0-0.7-0.8-1.30.8-0.7-0.7
Pavlov. Cond. lever-magazine prob. diff.0.10.10.30.4-0.50.50.40.50.40.4-0.3-0.4-0.30.30.3-0.40.40.10.20.40.00.30.3
Pavlov. Cond. response bias0.00.00.10.2-0.30.30.20.30.20.2-0.2-0.2-0.20.20.2-0.20.20.1-0.00.3-0.00.10.1
Time in closed arm before self-admin0.60.81.20.9-0.91.01.01.01.11.0-0.9-0.7-0.91.00.9-1.01.00.90.40.7-0.60.60.6
Time in closed arm after self-admin0.30.30.6-0.60.5-0.4-0.5-0.4-0.6-0.40.50.60.5-0.4-0.60.4-0.6-0.6-0.7-0.80.5-0.4-0.4
Time in open arm before self-admin0.70.71.2-0.81.1-1.0-1.1-0.9-1.0-0.90.90.60.9-0.9-0.80.9-0.9-0.8-0.6-0.60.6-0.7-0.7
Time in open arm after self-admin0.20.20.5-0.40.6-0.5-0.5-0.7-0.5-0.50.30.20.3-0.6-0.20.7-0.4-0.3-0.20.5-0.4-0.7-0.7
Bone: periosteal estimation0.00.00.00.00.1-0.1-0.1-0.0-0.1-0.00.1-0.10.1-0.0-0.10.00.1-0.00.1-0.20.20.20.2
Bone: periosteal perimeter1.01.61.9-1.31.3-1.4-1.4-1.3-1.3-1.31.31.21.3-1.3-1.31.3-1.2-1.3-1.3-1.31.2-1.1-1.1
Bone: post-yield work0.00.00.10.2-0.10.10.10.00.20.1-0.1-0.2-0.10.00.2-0.00.00.00.10.3-0.3-0.0-0.0
Progressive ratio test 1 active lever presses0.10.10.4-0.10.1-0.1-0.3-0.3-0.0-0.20.10.10.1-0.2-0.00.3-0.0-0.1-0.60.2-0.2-0.6-0.6
Progressive ratio test 1 breakpoint0.10.10.3-0.10.1-0.1-0.3-0.4-0.1-0.20.10.10.1-0.2-0.00.3-0.0-0.1-0.60.3-0.3-0.6-0.6
Progressive ratio test 1 inactive lever presses0.40.61.5-0.80.7-0.7-0.9-0.5-0.6-0.70.80.80.8-0.6-0.90.6-0.7-0.5-1.0-1.11.2-0.3-0.3
Progressive ratio test 2 active lever presses1.82.13.0-1.51.7-1.6-1.6-1.4-1.4-1.51.51.41.5-1.4-1.51.4-1.3-1.4-1.6-1.41.6-1.0-1.0
Progressive ratio test 2 breakpoint1.92.13.0-1.51.7-1.6-1.6-1.4-1.4-1.51.51.41.5-1.4-1.51.4-1.3-1.4-1.6-1.51.6-1.0-1.0
Progressive ratio test 2 inactive lever presses2.13.47.4-1.92.0-1.9-2.1-1.5-1.6-1.82.01.82.0-1.6-2.11.6-1.7-1.6-2.2-2.42.7-1.0-1.0
Incentive Sensitization - Responses1.82.64.2-1.71.9-1.8-1.7-1.4-1.6-1.61.71.61.7-1.5-1.81.5-1.6-1.5-1.5-1.92.1-0.7-0.7
Incentive Sensitization - Breakpoint2.02.64.3-1.71.9-1.8-1.7-1.5-1.6-1.61.71.61.8-1.5-1.81.5-1.6-1.5-1.5-1.92.1-0.7-0.7
Sum of active levers in priming session hrs 5-60.10.10.70.2-0.10.10.0-0.10.30.1-0.2-0.2-0.30.00.30.10.30.30.20.8-0.8-0.3-0.3
Progressive ratio2.64.15.42.3-2.02.01.91.81.92.0-2.1-2.3-2.12.02.1-1.92.21.92.02.1-2.21.81.8
Food seeking constrained by brief footshock1.11.42.0-1.40.9-1.0-1.1-1.1-1.4-1.11.21.31.2-1.2-1.21.2-1.4-1.4-1.4-1.10.9-1.1-1.1
Seeking ratio, punishment vs. effort4.66.68.7-2.92.4-2.5-2.4-2.4-2.7-2.52.62.92.7-2.5-2.72.5-2.8-2.6-2.5-2.72.6-2.1-2.1
Retroperitoneal fat weight1.46.17.62.6-2.52.72.82.72.52.7-2.6-2.4-2.62.62.5-2.62.42.32.12.1-2.22.12.1
Reaction time number correct0.50.91.3-1.11.1-1.0-0.9-0.9-1.1-0.90.91.10.9-0.9-1.00.9-0.9-1.0-1.1-1.20.7-0.6-0.6
Reaction time mean minus median0.10.20.40.4-0.50.30.30.30.50.3-0.4-0.5-0.40.30.4-0.30.40.10.60.6-0.40.20.2
Reaction time mean minus median AUC0.10.40.80.6-0.70.50.50.50.70.5-0.6-0.7-0.60.50.6-0.40.60.40.80.9-0.70.40.4
Reaction time num false alarms0.30.40.6-0.60.6-0.6-0.7-0.8-0.7-0.70.60.60.6-0.6-0.60.7-0.5-0.4-0.5-0.50.5-0.6-0.6
Reaction time num false alarms AUC0.10.10.3-0.30.3-0.3-0.4-0.5-0.4-0.40.30.30.3-0.3-0.20.4-0.2-0.1-0.2-0.1-0.0-0.5-0.5
Reaction time trials correct on left0.50.91.3-1.11.1-1.0-0.9-0.9-1.1-0.90.91.10.9-0.9-1.00.9-0.9-1.0-1.1-1.20.7-0.6-0.6
Reaction time trials on left0.50.91.4-1.11.1-1.0-0.9-0.9-1.1-0.90.91.10.9-0.9-1.00.9-0.9-1.1-1.1-1.20.7-0.7-0.7
Reaction time mean0.00.00.2-0.10.1-0.1-0.0-0.10.0-0.1-0.00.1-0.0-0.10.00.10.1-0.3-0.00.1-0.2-0.4-0.4
Reaction time mean AUC0.00.10.4-0.10.2-0.1-0.1-0.3-0.1-0.20.10.20.0-0.2-0.00.20.0-0.3-0.10.2-0.3-0.6-0.6
Median of all reaction times0.10.10.5-0.30.4-0.3-0.2-0.4-0.2-0.30.20.30.2-0.3-0.20.3-0.1-0.4-0.3-0.2-0.1-0.7-0.7
Reaction time omissions0.10.10.4-0.30.3-0.4-0.4-0.5-0.4-0.30.20.30.2-0.3-0.20.3-0.3-0.2-0.1-0.3-0.2-0.6-0.6
Reaction time false alarm rate0.00.00.10.0-0.1-0.0-0.1-0.20.0-0.10.0-0.0-0.0-0.00.00.10.10.20.20.1-0.1-0.2-0.2
Reaction time premature initiation rate2.43.34.82.0-2.01.91.81.92.21.9-1.9-1.8-1.91.91.9-1.92.02.11.41.9-1.61.21.2
Reaction time premature initiations0.81.52.21.3-1.31.31.21.31.51.3-1.3-1.1-1.31.31.2-1.31.41.40.61.1-1.10.70.7
Std. dev. reaction times0.10.20.60.4-0.40.30.40.20.50.3-0.4-0.4-0.50.30.5-0.20.50.20.50.7-0.8-0.2-0.2
Reaction time trials completed0.50.91.4-1.11.1-1.0-0.9-0.9-1.1-0.90.91.10.9-0.9-1.00.9-0.9-1.1-1.1-1.20.7-0.7-0.7
Reaction time trials AUC0.61.21.6-1.21.3-1.1-1.0-1.0-1.3-1.01.11.21.1-1.0-1.11.0-1.1-1.2-1.3-1.30.8-0.8-0.8
Run reversals in cocaine runway, females1.81.82.7-1.61.0-0.9-1.1-1.1-1.6-1.21.31.61.3-1.2-1.41.1-1.5-1.4-1.4-1.51.1-1.4-1.4
Run reversals in cocaine runway, males1.31.31.91.4-1.01.01.11.41.31.3-1.1-1.4-1.01.31.0-1.41.21.30.90.5-0.41.31.3
Latency to leave start box in cocaine runway0.40.51.40.7-0.70.50.60.70.60.7-0.6-0.7-0.60.70.6-0.70.70.60.70.4-0.41.21.2
Latency to leave start box in cocaine runway, F0.91.02.21.0-1.10.91.01.30.91.1-0.9-0.9-0.81.10.8-1.21.01.00.90.1-0.21.51.5
Latency to leave start box in cocaine runway, M0.30.30.7-0.60.7-0.7-0.7-0.8-0.6-0.70.60.30.6-0.7-0.50.8-0.5-0.6-0.5-0.10.2-0.3-0.3
Std. dev. time between licks in bursts4.66.39.2-2.72.6-2.6-2.6-2.2-2.6-2.52.62.42.7-2.4-2.72.3-2.6-2.6-2.5-3.03.0-1.6-1.6
Total sessions with >9 infusions0.60.71.5-0.90.8-0.7-0.8-0.6-0.7-0.80.90.90.9-0.7-0.90.7-0.8-0.8-1.0-1.21.2-0.1-0.1
Short access day 1 total inactive lever presses4.76.17.7-2.82.5-2.4-2.4-2.4-2.6-2.52.52.82.5-2.5-2.52.5-2.6-2.6-2.5-2.42.3-2.1-2.1
Short access day 10 total inactive lever presses0.20.41.80.5-0.40.30.40.80.40.5-0.3-0.5-0.20.60.2-0.70.50.50.6-0.60.81.31.3
Short access day 1 total infusions3.24.25.3-2.22.2-2.1-2.1-2.1-2.0-2.12.12.22.1-2.1-2.02.1-2.0-2.1-2.3-1.81.8-1.8-1.8
Short access day 10 total infusions2.53.25.1-1.91.8-1.7-1.8-1.8-1.6-1.81.81.91.8-1.8-1.71.8-1.8-1.7-2.3-1.41.5-1.9-1.9
Short access total infusions3.95.07.0-2.42.2-2.1-2.2-2.3-2.2-2.32.22.42.2-2.3-2.22.3-2.2-2.3-2.6-1.81.7-2.3-2.3
Short access day 1 locomotion0.50.60.8-0.90.8-0.7-0.8-0.7-0.8-0.80.80.90.8-0.8-0.80.8-0.7-0.6-0.7-0.70.9-0.4-0.4
Short access day 10 total locomotion0.00.10.4-0.0-0.10.20.1-0.10.10.0-0.10.1-0.2-0.00.20.00.00.0-0.50.3-0.4-0.7-0.7
Short access total locomotion0.00.10.2-0.20.1-0.1-0.2-0.3-0.1-0.20.10.20.1-0.2-0.10.3-0.1-0.1-0.40.2-0.1-0.5-0.5
One hour access (0.3 mA shock)1.01.22.4-1.11.1-1.0-1.1-1.2-0.9-1.11.01.00.9-1.1-0.91.1-1.0-1.1-1.6-0.60.5-1.4-1.4
Compulsive drug intake1.11.32.5-1.30.9-0.9-1.0-1.3-1.5-1.21.01.21.0-1.3-0.91.3-1.3-1.2-0.8-0.40.1-1.6-1.6
One hour access (shock baseline)0.30.51.2-0.60.9-0.8-0.8-0.6-0.3-0.60.70.50.7-0.5-0.70.5-0.4-0.4-1.0-0.81.1-0.4-0.4
Social response proportion0.20.20.40.4-0.60.60.40.50.60.6-0.6-0.3-0.60.60.5-0.60.40.60.40.3-0.60.20.2
Social responses0.40.50.90.8-0.60.60.60.60.90.7-0.7-0.8-0.80.70.8-0.70.80.80.90.9-0.80.50.5
Social time0.40.61.9-0.60.8-0.7-0.8-0.4-0.7-0.60.80.60.8-0.6-0.90.5-0.7-0.9-0.9-1.21.4-0.2-0.2
Soleus weight4.112.014.13.8-3.63.63.63.73.63.6-3.5-3.6-3.43.53.4-3.63.43.43.43.0-2.63.53.5
Bone: stiffness0.20.30.40.6-0.50.50.40.50.60.5-0.5-0.6-0.50.50.5-0.50.60.60.50.4-0.40.60.6
Tibialis anterior weight0.00.10.50.3-0.20.20.20.50.20.3-0.2-0.3-0.10.30.1-0.4-0.00.20.1-0.20.40.70.7
Time to tail flick, vehicle, before self-admin1.31.41.71.2-0.91.31.31.21.21.3-1.3-1.2-1.31.31.2-1.31.21.21.01.0-1.10.80.8
Time to tail flick, vehicle, after self-admin0.40.50.90.8-0.60.70.70.80.90.7-0.6-0.7-0.60.80.6-0.80.90.60.50.20.10.60.6
Time to tail flick, test, before self-admin0.10.10.80.3-0.20.30.2-0.10.30.1-0.3-0.2-0.30.10.40.00.30.20.10.9-0.8-0.2-0.2
Time to tail flick, test, after self-admin0.10.10.5-0.30.7-0.4-0.3-0.2-0.2-0.30.40.30.4-0.3-0.40.2-0.3-0.3-0.4-0.50.6-0.2-0.2
Delta time to tail flick, vehicle, before/after SA0.20.20.8-0.40.4-0.6-0.5-0.4-0.2-0.40.50.40.5-0.4-0.50.4-0.2-0.5-0.3-0.70.9-0.1-0.1
Delta time to tail flick, test, before/after SA0.30.30.7-0.60.8-0.7-0.6-0.4-0.5-0.50.60.50.6-0.5-0.60.4-0.5-0.5-0.5-0.80.8-0.4-0.4
Tibia length6.818.722.34.7-4.64.64.44.64.64.4-4.4-4.6-4.34.34.3-4.34.34.14.04.2-3.54.04.0
Ambulatory time before self-admin0.91.42.2-1.21.0-1.2-1.2-0.9-1.2-1.11.21.21.2-1.1-1.31.0-1.2-1.1-1.4-1.51.5-0.9-0.9
Ambulatory time after self-admin0.10.10.1-0.30.2-0.3-0.4-0.3-0.3-0.30.30.20.3-0.3-0.30.3-0.2-0.0-0.3-0.10.3-0.2-0.2
Bone: tissue strength2.92.94.21.9-1.71.71.71.91.71.8-1.6-1.8-1.61.81.6-1.91.71.61.71.0-0.92.12.1
Total heroin consumption1.72.03.01.6-1.61.41.21.71.41.5-1.3-1.5-1.21.61.2-1.61.51.61.40.7-0.51.71.7
Bone: trabecular number0.81.43.8-1.21.0-1.0-1.0-1.4-1.1-1.21.01.20.9-1.2-0.81.3-1.4-1.0-1.1-0.20.0-1.9-1.9
Bone: trabecular spacing1.72.35.21.6-1.41.41.41.81.41.5-1.3-1.6-1.21.61.2-1.71.71.41.50.5-0.32.32.3
Bone: trabecular thickness0.20.21.10.2-0.30.40.30.00.30.2-0.3-0.2-0.40.10.40.00.00.20.01.0-0.9-0.6-0.6
Bone: trabecular tissue density0.50.70.90.9-0.90.90.80.81.00.8-0.8-1.0-0.80.80.9-0.80.90.70.80.9-0.80.80.8
Water consumed over 24 hours0.10.10.60.3-0.30.30.30.50.30.3-0.2-0.3-0.10.40.1-0.50.30.20.2-0.30.50.70.7
Number of responses in last shaping day0.30.42.0-0.40.5-0.7-0.7-0.3-0.3-0.50.60.50.7-0.4-0.70.3-0.4-0.4-0.5-1.21.40.10.1