Fkbp5

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Liver gene expression Fkbp5 0.14 0.07 1.3e-06 0.06 0.05 0.04 0.02 7.9e-07 1.6e-06 8.2e-06 1.5e-03
2 NAcc alternative TSS NM_001012174.2 0.04 0.03 8.0e-03 0.01 0.02 0.01 0.01 1.3e-02 3.5e-03 1.0e-02 3.8e-02
3 NAcc alternative TSS XM_006256224.4 0.04 0.03 1.0e-03 0.03 0.03 0.04 0.03 9.7e-05 4.5e-04 5.7e-05 4.2e-04
4 Brain gene expression Fkbp5 0.14 0.09 2.2e-03 0.02 0.02 0.03 0.03 6.8e-03 3.0e-03 1.5e-03 1.1e-03
5 Adipose alternative TSS XM_006256224.4 0.03 0.02 3.2e-05 0.04 0.04 0.04 0.04 7.9e-05 6.7e-05 1.7e-05 2.1e-05
6 Adipose gene expression Fkbp5 0.04 0.02 6.7e-05 0.04 0.03 0.03 0.03 3.1e-05 1.1e-04 9.9e-05 1.0e-04
7 Adipose isoform ratio XM_006256224.4 0.04 0.03 2.7e-06 0.05 0.04 0.05 0.05 6.9e-06 1.3e-05 2.4e-06 2.0e-06
8 Brain mRNA stability Fkbp5 0.05 0.03 3.6e-07 0.09 0.07 0.08 0.08 1.1e-08 6.4e-07 9.4e-08 8.2e-08
9 NAcc gene expression Fkbp5 0.03 0.03 5.0e-03 0.01 0.01 0.01 0.01 6.4e-03 3.6e-02 2.4e-02 1.7e-02
10 Brain intron excision ratio chr20_6565063_6574970 0.06 0.04 1.3e-03 0.01 0.01 0 0 2.3e-02 2.1e-02 1.6e-01 1.3e-01
11 NAcc isoform ratio XM_006256224.4 0.03 0.02 1.8e-03 0.03 0.02 0.02 0.02 1.9e-04 8.7e-04 4.2e-03 8.7e-04
12 BLA mRNA stability Fkbp5 0.12 0.06 9.6e-09 0.1 0.15 0.14 0.14 5.5e-06 1.7e-08 4.7e-08 4.2e-08
13 BLA isoform ratio NM_001012174.2 0.07 0.04 1.1e-04 0.08 0.09 0.07 0.07 3.4e-05 2.1e-05 9.8e-05 9.3e-05
14 PL mRNA stability Fkbp5 0.03 0.02 3.1e-04 0.02 0.03 0.02 0.03 2.2e-03 1.7e-04 4.4e-03 8.3e-04
15 BLA alternative TSS NM_001012174.2 0.09 0.05 2.8e-05 0.09 0.1 0.09 0.09 2.3e-05 7.4e-06 1.6e-05 2.3e-05
16 BLA alternative TSS XM_006256224.4 0.13 0.07 1.7e-08 0.17 0.16 0.16 0.15 1.8e-09 4.7e-09 1.1e-08 1.3e-08
17 BLA isoform ratio XM_006256224.4 0.12 0.06 5.7e-08 0.15 0.15 0.15 0.14 1.3e-08 1.4e-08 2.1e-08 3.7e-08
18 NAcc mRNA stability Fkbp5 0.02 0.02 5.4e-03 0.02 0.02 0 0.02 4.1e-03 1.9e-03 8.6e-02 2.5e-03
19 PL isoform ratio XM_006256224.4 0.03 0.02 3.4e-04 0.02 0.03 0.02 0.03 2.0e-03 1.2e-04 3.7e-03 6.5e-04
20 PL alternative TSS XM_006256224.4 0.04 0.02 1.1e-04 0.03 0.04 0.03 0.04 2.0e-04 1.6e-05 1.6e-04 6.2e-05
21 PL alternative TSS NM_001012174.2 0.05 0.03 2.7e-03 0.01 0.02 0.02 0.01 2.7e-02 1.2e-03 3.6e-03 7.9e-03
22 PL isoform ratio NM_001012174.2 0.04 0.03 3.6e-03 0.01 0.02 0.01 0.01 4.4e-02 3.0e-03 1.2e-02 2.3e-02
23 Brain alternative TSS XM_006256224.4 0.11 0.07 1.1e-06 0.05 0.07 0.06 0.06 9.4e-06 6.9e-07 1.8e-06 7.4e-06
24 Brain isoform ratio XM_006256224.4 0.11 0.07 1.0e-05 0.04 0.05 0.05 0.04 7.7e-05 1.2e-05 8.6e-06 1.6e-04

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24
Bone: apparent density0.30.51.2-0.3-0.8-0.9-0.4-1.0-1.00.90.80.71.1-0.7-0.8-0.7-0.7-0.7-0.8-0.8-0.50.50.50.0-0.10.8-0.5
Area under the delay curve0.40.51.4-0.41.20.80.80.30.2-0.3-0.60.0-0.60.40.40.40.50.50.50.50.7-0.8-0.91.11.1-0.80.8
BMI with tail1.44.67.22.41.11.10.11.91.9-1.8-2.1-1.5-1.61.82.32.62.32.72.42.42.4-2.7-2.62.52.6-2.52.3
BMI without tail0.81.63.11.21.01.1-0.31.51.5-1.5-1.6-0.7-1.81.11.41.51.21.51.51.50.9-1.2-1.10.50.7-1.70.9
Body weight4.920.732.82.05.55.73.84.64.7-4.7-5.1-2.6-4.94.84.04.24.24.45.25.24.4-4.7-4.84.14.3-5.14.4
Weight adjusted by age1.01.13.50.21.61.91.70.20.1-0.1-1.3-0.2-0.71.40.50.60.70.71.11.11.1-1.1-1.21.51.5-0.90.1
Bone surface0.00.10.7-0.50.50.30.8-0.2-0.20.10.00.1-0.2-0.0-0.1-0.2-0.1-0.20.10.1-0.10.20.1-0.2-0.20.0-0.3
Bone volume0.00.00.2-0.20.50.30.4-0.1-0.10.1-0.10.2-0.20.0-0.00.00.00.10.20.20.1-0.2-0.20.40.3-0.30.1
Breakpoint value in progressive ratio session0.30.41.70.8-1.3-0.70.1-0.2-0.30.40.2-1.20.90.20.30.10.2-0.0-0.5-0.50.10.30.3-0.7-0.70.9-0.9
Number of licking bursts0.70.82.2-1.2-0.6-0.7-0.4-0.7-0.70.71.00.80.2-1.0-0.7-0.9-0.9-0.9-0.7-0.7-1.21.21.2-1.5-1.50.6-0.2
Context. condit. distance diff. score0.81.03.2-1.80.20.00.5-0.8-0.80.80.80.70.1-1.0-1.0-1.3-1.0-1.3-0.8-0.8-1.21.31.2-1.4-1.40.9-0.9
Locomotion velocity, session 11.21.33.8-2.00.3-0.6-0.5-1.5-1.41.51.21.80.4-1.5-1.5-1.4-1.5-1.3-0.8-0.8-1.31.00.9-0.3-0.40.5-0.1
Locomotion distance, session 13.14.05.4-1.6-1.9-2.3-2.1-2.2-2.12.12.22.21.9-2.3-2.2-2.1-2.2-2.0-2.1-2.1-2.22.02.0-1.1-1.31.8-1.3
Locomotion velocity, session 20.60.71.7-1.0-0.3-0.70.1-0.9-1.01.01.10.30.1-1.0-0.5-0.8-0.7-0.8-0.5-0.5-0.91.01.0-1.3-1.30.7-1.0
Locomotion distance, session 20.81.11.6-0.9-0.7-0.9-0.6-1.2-1.11.21.01.11.0-1.1-1.3-1.2-1.2-1.2-1.1-1.1-1.11.11.0-0.6-0.71.1-1.0
Locomotion velocity, session 30.50.52.6-0.41.00.3-1.20.30.3-0.3-0.21.0-1.6-0.40.20.40.00.50.90.9-0.3-0.3-0.30.20.2-1.51.3
Locomotion distance, session 30.80.94.2-1.0-0.3-0.9-2.0-0.8-0.80.81.01.7-0.1-1.4-0.9-0.8-1.1-0.7-0.5-0.5-1.30.80.8-0.5-0.5-0.10.1
Stereotopy head waving bouts, day 31.51.75.0-0.32.02.21.61.41.5-1.4-1.5-0.8-2.01.21.10.91.01.01.51.50.8-0.8-0.90.20.3-1.51.2
Stereotopy head waving duration, day 30.10.21.4-0.60.90.91.20.10.1-0.0-0.4-0.1-0.50.3-0.0-0.10.1-0.10.30.30.1-0.0-0.10.00.0-0.2-0.1
Locomotion velocity, session 70.20.21.2-0.40.6-0.1-0.3-0.6-0.60.50.11.10.1-0.4-0.7-0.5-0.5-0.3-0.1-0.1-0.2-0.1-0.21.00.8-0.2-0.3
Locomotion distance, session 70.91.23.1-1.2-0.0-0.6-0.6-1.4-1.41.40.91.81.0-1.1-1.6-1.4-1.4-1.3-1.0-1.0-1.00.80.70.40.20.8-1.0
Stereotopy head waving bouts, day 70.40.52.2-0.20.80.5-0.90.60.6-0.6-0.40.5-1.4-0.10.40.50.20.50.70.7-0.1-0.3-0.30.20.2-1.31.5
Stereotopy head waving duration, day 70.91.13.30.31.20.9-0.51.01.0-1.0-0.8-0.0-1.80.41.01.10.81.11.31.30.5-0.9-0.90.50.6-1.81.7
Locomotion velocity, session 80.50.63.7-1.91.10.81.6-0.3-0.30.30.20.3-0.5-0.4-0.5-0.9-0.6-0.9-0.1-0.1-0.70.80.7-1.0-1.00.3-0.1
Locomotion distance, session 81.11.63.6-1.9-0.3-0.3-0.1-1.0-1.01.01.11.20.6-1.3-1.4-1.6-1.5-1.6-1.2-1.2-1.61.71.6-1.5-1.61.2-1.2
Degree of sensitization distance0.50.55.50.20.40.82.3-0.0-0.00.1-0.6-1.00.70.90.0-0.10.3-0.1-0.1-0.10.7-0.2-0.30.30.30.8-1.4
Degree of sensitization stereotypy0.30.32.8-0.30.0-0.5-1.7-0.1-0.20.10.41.0-0.7-0.8-0.10.0-0.30.10.10.1-0.50.10.2-0.1-0.1-0.70.9
Conditioned locomotion2.73.15.31.31.62.02.22.12.0-2.0-2.1-2.3-1.92.02.11.82.01.81.81.81.8-1.5-1.50.40.6-1.50.9
Cocaine response after cond. corrected0.50.61.21.10.10.60.31.01.0-1.0-1.1-0.9-0.60.91.00.90.90.90.70.70.7-0.6-0.50.00.1-0.60.3
Cocaine response after cond. not corrected0.50.51.60.50.51.00.71.11.1-1.1-1.3-0.7-0.90.90.80.60.70.60.70.70.4-0.3-0.3-0.3-0.2-0.60.2
Cocaine response before conditioning0.20.21.4-1.21.01.00.90.10.1-0.0-0.30.2-0.50.0-0.3-0.5-0.3-0.40.00.0-0.30.30.2-0.3-0.3-0.0-0.1
Saline control response1.21.66.72.6-0.40.20.21.10.9-1.0-1.6-1.70.01.51.41.61.51.50.80.81.6-1.4-1.31.11.2-0.5-0.2
Bone: connectivity density0.20.41.0-0.4-0.5-0.50.3-0.9-0.90.90.70.31.0-0.5-0.7-0.6-0.6-0.6-0.7-0.7-0.30.40.40.0-0.10.8-0.7
Bone: cortical apparent density0.30.41.71.3-0.60.0-0.60.90.9-0.9-0.7-0.60.20.70.60.70.60.60.20.20.5-0.5-0.40.40.4-0.20.3
Bone: cortical area0.10.20.6-0.10.60.3-0.20.10.0-0.1-0.20.6-0.50.10.10.20.10.30.40.40.1-0.4-0.40.70.6-0.70.8
Bone: cortical porosity0.40.52.0-1.30.90.2-0.5-0.6-0.50.50.31.4-0.1-0.6-0.9-0.6-0.7-0.40.00.0-0.4-0.0-0.11.00.9-0.40.9
Bone: cortical porosity0.40.52.2-1.51.10.40.2-0.6-0.50.50.21.20.1-0.4-1.0-0.8-0.7-0.6-0.1-0.1-0.30.0-0.11.00.8-0.10.7
Bone: cortical thickness0.50.86.60.7-1.1-1.4-2.6-0.8-0.80.70.71.60.7-0.9-0.6-0.1-0.60.0-0.5-0.5-0.4-0.1-0.10.90.8-0.20.5
Bone: cortical thickness0.40.42.81.7-1.1-0.8-1.2-0.0-0.10.00.0-0.30.50.20.50.80.50.70.10.10.5-0.6-0.50.70.7-0.2-0.1
Bone: cortical tissue density0.30.41.51.2-0.40.2-0.41.00.9-1.0-0.8-0.70.00.80.60.70.60.70.30.30.6-0.5-0.50.40.4-0.30.3
Condit. Reinf. active minus inactive responses0.91.03.1-0.7-0.3-0.90.4-1.6-1.71.71.10.51.4-0.8-1.1-1.0-0.8-0.9-0.9-0.9-0.40.50.40.40.31.2-1.5
Condit. Reinf. active-inactive response ratio0.20.21.30.7-0.6-0.70.4-0.4-0.40.40.2-0.70.90.10.10.10.20.0-0.2-0.20.4-0.2-0.10.30.20.6-1.1
Condit. Reinf. active responses0.30.41.4-0.10.0-0.50.5-1.0-1.21.10.50.10.9-0.3-0.5-0.4-0.2-0.3-0.3-0.30.2-0.2-0.20.90.80.6-0.9
Condit. Reinf. inactive responses0.10.20.70.1-0.3-0.3-0.2-0.6-0.60.60.20.20.7-0.1-0.3-0.1-0.2-0.1-0.3-0.30.1-0.2-0.20.80.70.2-0.2
Incentive salience index mean0.50.72.3-1.20.3-0.40.6-1.4-1.51.50.90.70.7-0.8-0.9-0.9-0.7-0.8-0.5-0.5-0.40.40.30.20.10.7-0.9
Condit. Reinf. lever presses0.30.41.4-1.20.6-0.00.5-1.0-1.21.10.60.7-0.0-0.6-0.6-0.6-0.6-0.6-0.2-0.2-0.40.40.3-0.0-0.10.1-0.3
Condit. Reinf. active minus inactive responses0.50.61.5-1.0-0.2-0.40.6-0.8-0.80.80.80.30.9-0.5-0.9-1.1-0.8-1.1-0.8-0.8-0.70.90.8-0.5-0.61.1-1.2
Condit. Reinf. active-inactive response ratio0.20.20.7-0.60.10.10.7-0.2-0.20.20.1-0.00.5-0.1-0.5-0.7-0.4-0.7-0.4-0.4-0.30.50.5-0.4-0.40.7-0.8
Condit. Reinf. active responses0.60.81.4-1.0-0.3-0.70.4-1.0-1.11.01.20.50.9-0.7-1.0-1.1-0.9-1.1-0.9-0.9-0.80.90.9-0.6-0.71.1-1.0
Condit. Reinf. inactive responses0.00.00.1-0.00.10.00.1-0.1-0.10.20.20.1-0.20.00.10.10.10.20.10.10.1-0.1-0.20.20.2-0.20.3
Condit. Reinf. lever presses3.04.16.9-1.3-1.9-2.0-0.7-2.2-2.32.32.11.22.6-1.8-2.2-2.2-2.0-2.3-2.4-2.4-1.82.02.0-1.2-1.42.6-2.3
Condit. Reinf. lever reinforcers received1.31.83.1-1.4-0.7-1.20.0-1.6-1.61.61.80.91.4-1.3-1.5-1.6-1.4-1.6-1.4-1.4-1.21.31.3-0.8-0.91.6-1.4
Conditioned reinforcement - actives0.60.62.4-0.91.61.20.30.00.0-0.1-0.71.1-0.90.3-0.20.1-0.00.30.80.80.2-0.7-0.81.31.2-1.11.0
Conditioned reinforcement - inactives0.20.21.4-0.10.1-0.1-0.60.10.1-0.00.11.20.1-0.5-0.6-0.5-0.6-0.5-0.3-0.3-0.60.40.4-0.0-0.10.0-0.6
Conditioned locomotion0.91.04.1-0.61.91.71.6-0.2-0.20.2-1.00.7-0.40.7-0.10.10.20.30.80.80.8-1.0-1.22.01.9-0.80.4
Patch foraging indifference point 0 sec0.50.82.21.20.00.3-0.51.11.1-1.2-0.9-0.4-0.40.80.81.00.81.00.60.60.8-1.0-0.91.01.0-1.01.5
Patch foraging indifference point AUC0.30.31.1-1.00.4-0.10.4-0.1-0.10.10.60.3-0.5-0.5-0.3-0.5-0.4-0.6-0.3-0.3-0.70.70.7-1.1-1.00.2-0.7
Delay disc. indifference point, 0s delay0.00.00.2-0.20.30.20.1-0.2-0.20.20.10.4-0.0-0.0-0.2-0.1-0.1-0.10.10.1-0.0-0.1-0.10.30.3-0.1-0.5
Delay disc. indifference point, 16s delay0.40.43.0-1.00.90.90.10.10.1-0.2-0.30.8-0.40.4-0.10.0-0.10.10.40.40.1-0.4-0.50.90.8-0.71.7
Delay disc. indifference point, 2s delay0.30.41.1-1.10.0-0.20.7-0.8-0.90.80.30.20.8-0.3-0.6-0.6-0.4-0.6-0.7-0.7-0.10.30.20.20.10.7-1.0
Delay disc. indifference point, 24s delay1.91.94.9-0.22.01.71.20.80.8-0.8-1.30.0-1.11.10.70.90.91.11.41.41.3-1.6-1.72.22.1-1.61.9
Delay disc. indifference point, 4s delay0.60.61.00.51.00.70.90.70.7-0.7-0.8-0.9-0.90.71.00.91.00.90.70.61.0-0.9-0.90.50.6-0.7-0.2
Delay disc. indifference point, 8s delay0.91.02.90.11.71.11.50.40.2-0.3-0.8-0.4-1.00.70.70.80.90.91.00.91.1-1.2-1.31.41.4-1.10.5
Indifference point function ln k0.20.31.1-0.90.0-0.2-0.7-0.6-0.70.70.51.1-0.0-0.8-0.7-0.6-0.7-0.5-0.4-0.4-0.70.50.5-0.3-0.40.00.3
Indifference point function log k0.20.31.1-0.90.0-0.2-0.7-0.6-0.70.70.51.1-0.0-0.8-0.7-0.6-0.7-0.5-0.4-0.4-0.70.50.5-0.3-0.40.00.3
Patch foraging total patch changes 0 sec0.50.81.81.3-0.00.2-0.81.11.1-1.1-0.9-0.2-0.40.80.71.00.71.00.60.60.8-1.0-0.91.01.1-1.01.3
Patch foraging total patch changes 12 sec0.10.11.40.4-0.6-0.7-1.20.20.2-0.20.30.4-0.1-0.30.00.1-0.10.0-0.3-0.3-0.30.20.3-0.3-0.3-0.20.1
Patch foraging total patch changes 18 sec0.91.14.32.1-0.2-0.0-0.81.41.4-1.4-1.0-0.8-0.60.91.21.41.21.30.80.81.0-1.1-1.00.70.8-1.00.2
Patch foraging total patch changes 24 sec0.40.52.20.9-1.5-1.4-1.5-0.2-0.20.20.40.31.1-0.4-0.3-0.1-0.3-0.1-0.8-0.8-0.20.20.30.20.10.6-0.6
Patch foraging total patch changes 6 sec0.30.41.81.3-0.6-0.5-1.00.80.8-0.8-0.4-0.40.10.40.60.70.50.70.00.00.5-0.6-0.50.50.5-0.40.4
Patch foraging time to switch 0 sec1.32.16.72.6-0.30.50.21.11.1-1.1-1.6-2.1-0.41.51.92.01.91.91.21.21.9-1.7-1.61.11.3-0.90.2
Patch foraging water rate 0 sec0.20.31.5-0.90.1-0.2-0.4-0.2-0.10.10.51.20.2-0.5-0.9-0.8-0.9-0.8-0.5-0.5-0.80.60.6-0.2-0.30.20.3
Patch foraging water rate 12 sec0.30.43.3-0.2-0.5-0.8-1.8-0.2-0.10.10.61.10.1-0.8-0.6-0.5-0.7-0.5-0.4-0.4-0.90.60.6-0.5-0.50.0-0.3
Patch foraging water rate 18 sec0.10.21.3-0.1-0.7-0.30.1-0.1-0.10.1-0.00.11.10.0-0.6-0.5-0.4-0.5-0.7-0.7-0.20.30.30.20.10.80.3
Patch foraging water rate 24 sec0.40.62.3-0.2-1.0-0.9-1.5-0.2-0.20.20.40.70.4-0.7-0.6-0.6-0.7-0.6-0.7-0.7-1.00.91.0-1.0-1.00.5-0.1
Patch foraging water rate 6 sec0.20.31.0-0.6-0.4-0.4-1.0-0.2-0.10.10.41.00.2-0.6-0.7-0.6-0.7-0.6-0.4-0.4-0.90.70.7-0.6-0.60.20.1
Seeking ratio, delayed vs. immediate footshock0.30.31.20.5-0.5-0.0-0.31.11.1-1.1-0.3-0.8-0.50.10.70.50.50.30.20.10.00.20.3-1.1-0.9-0.10.1
Distance traveled before self-admin1.11.13.40.80.50.80.11.81.8-1.8-1.1-1.3-1.51.11.41.11.10.90.90.90.5-0.4-0.3-0.9-0.7-0.90.5
Distance traveled after self-admin0.70.82.31.2-0.30.60.41.41.4-1.3-0.9-1.5-0.71.01.10.80.90.60.50.50.4-0.00.1-1.3-1.1-0.1-0.3
Extensor digitorum longus weight0.21.02.7-1.6-0.0-0.11.0-0.8-0.80.80.80.40.4-0.6-0.9-1.2-0.9-1.2-0.8-0.8-1.01.31.2-1.5-1.51.1-0.8
Bone: elastic displacement0.30.31.8-0.60.3-0.2-1.1-0.5-0.50.40.31.30.2-0.6-0.8-0.5-0.6-0.3-0.2-0.2-0.4-0.1-0.11.00.9-0.30.5
Bone: elastic work0.10.21.30.20.2-0.2-0.3-0.3-0.40.30.00.60.3-0.1-0.3-0.0-0.10.10.00.00.2-0.4-0.41.11.0-0.20.2
Bone: endosteal estimation2.75.918.50.73.23.44.32.42.3-2.3-2.6-2.8-2.72.82.52.02.52.02.62.62.4-2.0-2.10.81.0-1.91.1
Bone: endosteal perimeter1.53.18.40.42.22.32.92.12.1-2.1-1.9-2.2-2.22.01.91.41.81.41.91.91.5-1.1-1.2-0.10.1-1.30.7
Epididymis fat weight2.14.916.84.1-0.3-0.3-2.01.61.7-1.7-1.7-1.0-0.51.62.02.72.12.81.91.92.4-2.9-2.73.43.4-2.11.4
Delta time in closed arm before/after self-admin1.31.21.91.11.11.10.31.11.1-1.1-1.2-0.4-1.11.11.01.11.01.21.21.21.0-1.2-1.21.21.2-1.40.9
Delta time in open arm before/after self-admin0.70.71.5-0.5-0.9-0.8-0.2-1.1-1.21.10.90.41.2-0.6-0.8-0.8-0.7-0.8-1.0-1.0-0.60.70.6-0.3-0.41.0-0.9
Diff in mean of infusions in LGA sessions0.50.51.80.2-1.3-1.00.1-0.5-0.60.60.5-0.51.3-0.4-0.5-0.6-0.4-0.6-0.9-0.9-0.30.70.7-0.6-0.71.3-0.8
Delay discount exponential model param0.40.41.30.5-1.2-0.8-0.8-0.2-0.20.20.5-0.10.6-0.3-0.3-0.3-0.4-0.4-0.4-0.4-0.60.70.8-1.1-1.00.7-0.8
Extinction: sum of active levers before priming0.10.10.3-0.2-0.5-0.1-0.5-0.1-0.20.20.30.30.3-0.0-0.3-0.3-0.4-0.3-0.5-0.5-0.40.40.5-0.5-0.50.30.2
Active lever presses in extinction session 60.50.52.90.9-0.00.60.9-0.2-0.30.3-0.8-0.21.00.8-0.10.20.30.30.10.10.9-0.8-0.91.71.60.2-0.0
Bone: final force3.65.88.22.91.61.71.12.42.3-2.4-2.5-2.1-1.92.62.62.82.72.92.62.62.7-2.8-2.82.32.4-2.51.9
Bone: final moment2.84.56.42.41.51.61.02.01.9-2.0-2.2-1.7-1.72.22.22.42.32.52.32.32.4-2.5-2.52.22.3-2.21.6
Food consumed during 24 hour testing period0.91.14.81.40.10.71.90.90.8-0.8-0.8-2.2-0.11.41.31.11.40.90.60.61.4-0.8-0.80.10.20.1-0.7
Glucose0.71.17.8-2.81.70.81.4-0.6-0.50.50.71.2-0.6-0.7-1.1-1.3-1.1-1.2-0.1-0.1-1.00.90.7-0.5-0.60.10.2
Heart weight2.13.05.3-2.3-0.7-1.0-0.3-1.9-1.91.91.52.01.7-1.7-2.2-2.2-2.1-2.1-2.0-2.0-1.81.71.6-0.7-0.91.7-0.6
Delay discount hyperbolic model param0.20.20.90.6-0.9-0.5-0.8-0.1-0.00.10.3-0.10.4-0.1-0.2-0.2-0.3-0.3-0.2-0.2-0.50.50.6-0.8-0.80.4-0.4
Intermittent access intake day 1-15 change0.80.81.70.70.50.5-0.31.01.0-1.0-0.8-1.0-1.30.81.21.21.11.11.11.10.8-0.8-0.70.10.2-1.10.4
Intermittent access intake escalation1.31.32.60.70.90.90.31.31.3-1.4-1.0-1.4-1.61.11.51.41.41.31.41.41.0-0.9-0.90.00.2-1.30.5
Intermittent access intake escalation 20.20.21.2-1.10.70.50.60.00.1-0.10.3-0.1-0.7-0.2-0.0-0.3-0.1-0.30.10.1-0.30.40.3-0.8-0.7-0.10.2
Intermitt. access day 1 inactive lever presses0.50.63.0-0.7-0.7-0.7-1.60.50.6-0.50.3-0.1-0.5-0.70.1-0.1-0.3-0.2-0.2-0.2-0.80.80.9-1.7-1.60.00.2
Intermitt. access day 15 inactive lever presses1.41.53.10.61.11.50.31.71.7-1.7-1.5-1.0-1.81.01.41.31.21.21.41.40.9-0.9-0.90.00.2-1.51.2
Intermitt. access escalation Index0.80.72.2-0.1-1.2-1.5-1.3-0.5-0.50.50.9-0.10.3-1.0-0.2-0.3-0.4-0.4-0.7-0.7-0.70.80.9-1.3-1.30.6-0.9
Intermittent access day 1 total infusions0.81.04.7-1.30.50.3-0.1-1.5-1.51.50.32.20.7-0.7-1.5-1.2-1.2-1.0-0.4-0.4-0.70.30.21.00.80.3-0.3
Intermittent access day 15 total infusions0.20.20.5-0.20.60.5-0.4-0.2-0.30.3-0.50.6-0.40.1-0.10.1-0.00.20.50.50.1-0.4-0.40.70.7-0.6-0.0
Intermittent access terminal intake (last 3 days)0.30.31.1-0.51.10.9-0.0-0.3-0.40.4-0.60.9-0.60.2-0.10.1-0.00.20.70.70.1-0.5-0.61.11.0-0.80.1
Intermittent access total infusions0.40.42.3-0.90.60.6-0.0-0.9-0.90.9-0.21.50.2-0.2-0.8-0.6-0.7-0.40.00.0-0.3-0.1-0.21.00.9-0.1-0.1
Intermittent access day 1 locomotion0.20.20.8-0.10.90.90.30.30.3-0.3-0.80.5-0.50.30.00.10.10.10.50.50.2-0.3-0.40.50.5-0.4-0.3
Intermittent access day 15 total locomotion4.75.18.71.42.73.02.12.52.5-2.5-2.7-1.4-2.52.52.12.12.22.12.62.62.2-2.2-2.21.71.9-2.31.0
Intermittent access total locomotion2.02.35.40.82.12.31.91.51.5-1.5-2.0-0.5-1.41.81.11.11.31.21.61.61.5-1.5-1.51.51.5-1.40.3
Intermittent access standard deviation1.01.01.91.10.30.7-0.11.31.3-1.4-1.2-1.2-1.01.01.31.31.21.21.11.11.0-1.0-0.90.30.5-1.00.6
Left kidney weight2.67.314.01.03.63.72.22.92.8-2.9-3.3-1.1-3.22.92.22.32.32.53.13.12.3-2.6-2.72.12.3-3.22.6
Right kidney weight3.08.316.91.33.74.12.53.23.1-3.1-3.6-1.8-3.83.22.72.62.72.73.43.42.5-2.6-2.71.51.8-3.41.7
Cocaine induced anxiety0.40.43.30.1-0.6-0.5-0.70.40.3-0.40.2-0.7-0.5-0.20.40.10.1-0.0-0.1-0.1-0.40.70.7-1.8-1.70.2-0.7
Post-drug Anxiety0.50.63.40.5-1.0-0.9-0.2-0.1-0.20.20.5-1.00.3-0.40.3-0.10.1-0.2-0.4-0.4-0.30.70.8-1.6-1.50.9-1.8
Baseline Anxiety0.30.31.70.4-0.7-0.50.4-0.7-0.60.70.3-0.21.3-0.1-0.4-0.3-0.2-0.3-0.6-0.60.2-0.1-0.00.70.60.9-0.9
Tail length1.33.815.6-1.63.84.02.82.12.2-2.2-2.3-0.3-3.21.90.90.50.90.72.02.00.6-0.6-0.8-0.2-0.0-2.01.4
Length with tail2.48.726.8-0.95.15.23.93.13.2-3.2-3.3-0.8-3.83.11.81.62.01.83.23.22.0-2.2-2.41.81.9-3.22.9
Length without tail2.04.410.60.13.03.33.11.92.0-2.0-2.3-1.1-1.82.41.41.41.71.62.12.12.0-2.0-2.22.22.2-1.92.4
Times rat made contact with spout1.82.14.8-0.0-2.1-2.2-1.6-1.6-1.61.61.50.92.2-1.3-1.3-1.2-1.2-1.2-1.7-1.7-1.01.11.2-0.5-0.61.7-1.5
Lifetime Intake0.40.41.8-0.71.00.90.3-0.6-0.70.7-0.51.2-0.00.1-0.5-0.3-0.3-0.10.40.40.1-0.4-0.51.31.2-0.4-0.1
Liver weight, left4.26.711.91.03.43.53.12.92.8-2.8-2.8-2.5-3.42.92.72.32.72.43.03.02.4-2.2-2.20.91.2-2.60.9
Liver weight, right2.54.114.8-1.43.63.93.02.42.3-2.3-2.1-1.0-3.52.01.40.81.20.82.22.20.7-0.5-0.6-0.9-0.6-2.00.8
Locomotor activity0.20.31.20.20.10.3-0.60.80.8-0.8-0.2-0.0-1.10.20.50.40.20.30.40.4-0.20.20.3-1.1-0.9-0.60.1
Locomotor testing distance0.20.31.70.7-1.0-0.9-1.30.20.2-0.20.4-0.1-0.2-0.30.40.30.10.2-0.1-0.1-0.30.30.4-1.1-0.9-0.1-0.3
Locomotor testing rearing0.81.32.61.40.40.90.61.51.4-1.5-1.4-1.6-1.21.31.61.41.41.31.21.21.0-0.8-0.7-0.3-0.1-0.90.2
Locomotion in novel chamber0.70.91.8-0.9-0.7-1.2-0.8-1.1-1.01.01.31.30.9-1.1-1.1-1.0-1.1-1.0-1.1-0.9-1.00.80.8-0.3-0.40.70.4
Locomotion in novel chamber post-restriction1.82.13.31.61.01.30.71.51.4-1.5-1.6-1.3-1.11.81.51.61.61.71.41.41.6-1.7-1.71.51.5-1.41.3
Fecal boli incidents, locomotor time 10.20.21.40.40.10.31.2-0.1-0.20.1-0.2-0.50.60.50.00.00.20.0-0.1-0.10.5-0.3-0.40.60.50.4-0.2
Change in fecal boli incidents, locomotor task0.10.11.10.3-0.1-0.5-0.4-0.2-0.20.20.4-0.0-0.3-0.50.20.20.10.10.10.2-0.00.00.1-0.3-0.2-0.1-1.1
Time >=10cm from walls, locomotor time 12.02.16.52.00.00.30.81.81.7-1.8-1.3-2.6-1.01.22.11.92.01.71.31.31.7-1.3-1.10.00.2-0.80.2
Bouts of movement, locomotor time 10.30.41.80.5-0.6-0.3-0.30.10.0-0.10.3-0.20.2-0.3-0.1-0.3-0.2-0.4-0.7-0.7-0.50.70.8-1.3-1.20.6-1.3
Total resting periods, locomotor time 10.20.21.20.4-0.10.30.40.30.3-0.3-0.1-0.4-0.10.10.1-0.20.0-0.2-0.4-0.4-0.20.40.5-1.0-0.90.4-1.1
Rest time, locomotor task time 10.10.11.0-0.51.00.70.20.10.1-0.2-0.20.6-0.70.1-0.2-0.2-0.1-0.10.10.1-0.1-0.0-0.10.30.2-0.50.2
Distance moved, locomotor task time 10.30.31.30.8-0.3-0.10.20.30.3-0.3-0.4-1.2-0.10.60.80.80.80.80.70.70.8-0.6-0.60.20.3-0.30.2
Vertical activity count, locomotor time 11.31.46.02.0-0.30.11.20.80.7-0.7-0.9-2.4-0.11.21.61.51.61.41.01.01.6-1.2-1.10.40.6-0.2-0.5
Time >=10cm from walls, locomotor time 24.24.47.32.21.61.31.81.51.4-1.4-2.0-2.3-1.41.92.42.52.52.52.42.42.7-2.6-2.62.32.4-1.90.7
Bouts of movement, locomotor time 20.50.61.80.20.30.91.11.11.2-1.1-0.8-1.3-0.70.90.90.40.80.30.20.20.40.00.1-1.1-0.90.0-0.8
Total resting periods, locomotor time 20.40.42.3-0.3-0.00.40.60.60.7-0.7-0.2-0.8-0.30.30.3-0.10.2-0.3-0.4-0.3-0.20.60.7-1.5-1.40.5-1.2
Rest time, locomotor task time 20.20.31.4-0.40.10.3-0.40.70.7-0.8-0.10.2-0.7-0.20.0-0.2-0.2-0.3-0.3-0.4-0.60.60.6-1.2-1.1-0.10.2
Distance moved, locomotor task time 22.63.06.41.71.51.41.70.80.7-0.7-1.5-1.5-0.91.91.51.81.81.92.02.02.2-2.3-2.32.52.5-1.50.8
Vertical activity count, locomotor time 22.12.34.71.41.31.32.20.60.6-0.5-1.4-1.7-0.51.91.31.51.61.51.61.62.0-1.9-2.02.02.1-0.9-0.0
Light reinforcement 11.73.26.22.40.50.80.42.12.0-2.1-1.7-2.4-1.91.72.52.42.22.21.91.91.8-1.6-1.50.20.5-1.80.9
Light reinforcement 22.33.07.81.71.01.21.71.91.9-1.9-1.7-2.8-1.71.82.32.02.21.92.02.01.9-1.6-1.50.40.6-1.41.0
Bone: marrow area2.86.118.80.83.23.54.32.42.4-2.4-2.7-2.9-2.72.92.52.12.62.12.72.72.5-2.0-2.10.91.1-1.91.1
Bone: maximum diameter0.30.62.9-1.11.71.51.70.60.6-0.6-0.7-0.1-1.20.60.2-0.00.20.00.70.70.1-0.1-0.2-0.3-0.2-0.60.5
Bone: maximum force1.12.03.21.21.41.20.81.01.0-1.0-1.3-0.7-1.31.31.31.51.41.61.61.61.6-1.8-1.81.81.8-1.71.3
Bone: maximum moment0.71.32.80.81.41.00.80.70.6-0.7-1.0-0.4-0.91.00.91.11.01.21.31.31.3-1.5-1.51.71.7-1.41.0
Mean time between licks in bursts1.31.97.3-2.70.40.31.0-0.6-0.60.61.20.9-0.5-1.1-1.0-1.6-1.3-1.6-0.8-0.8-1.71.91.8-2.5-2.50.9-0.4
Mean num. licks in bursts0.30.31.40.9-0.8-0.8-0.7-0.4-0.40.40.1-0.11.2-0.0-0.3-0.1-0.1-0.0-0.5-0.50.2-0.2-0.20.90.80.6-0.8
Cd content in liver1.61.85.91.50.80.80.40.80.8-0.8-1.2-0.7-0.31.21.01.41.31.51.21.21.7-1.9-1.92.42.4-1.21.1
Co content in liver2.32.76.32.50.50.5-0.11.31.2-1.3-1.3-1.6-1.01.41.92.22.02.21.71.72.0-2.1-2.01.81.9-1.61.0
Cu content in liver2.73.37.4-0.2-2.3-2.7-2.4-2.2-2.22.22.01.82.4-1.9-1.8-1.5-1.8-1.5-2.0-2.0-1.51.31.3-0.2-0.41.7-1.6
Fe content in liver3.64.38.10.52.82.30.82.12.3-2.2-2.1-0.5-2.61.71.61.81.61.92.42.41.7-2.1-2.22.12.2-2.82.9
K content in liver1.51.54.3-2.1-0.1-0.5-0.3-1.3-1.21.31.41.40.4-1.4-1.4-1.5-1.4-1.5-1.0-1.0-1.51.41.3-1.1-1.20.9-0.5
Mg content in liver4.04.110.4-3.2-0.1-0.9-0.0-2.4-2.42.42.32.00.9-2.2-2.2-2.5-2.3-2.4-1.7-1.7-2.22.32.1-1.8-1.91.7-1.5
Mn content in liver0.91.04.2-2.11.00.71.8-0.5-0.60.60.50.1-0.5-0.4-0.6-1.1-0.7-1.1-0.3-0.3-0.81.21.0-1.6-1.60.7-0.9
Na content in liver0.10.10.2-0.10.1-0.1-0.40.50.4-0.5-0.20.0-0.4-0.10.0-0.0-0.1-0.10.00.0-0.30.20.3-0.5-0.4-0.20.2
Rb content in liver0.20.21.10.00.70.41.1-0.3-0.40.4-0.1-0.40.10.30.10.10.30.20.30.30.6-0.5-0.60.80.8-0.0-0.2
Se content in liver4.25.116.6-4.10.2-0.70.2-2.2-2.32.32.32.40.5-2.4-2.5-2.9-2.6-2.8-1.8-1.8-2.82.72.6-2.4-2.51.6-1.1
Sr content in liver0.20.20.70.4-0.10.00.6-0.3-0.40.3-0.0-0.20.80.2-0.1-0.00.10.0-0.2-0.20.4-0.3-0.40.80.70.4-0.4
Zn content in liver0.30.42.1-1.01.40.90.8-0.1-0.10.1-0.20.6-0.60.1-0.2-0.1-0.10.00.50.50.2-0.4-0.50.90.8-0.60.8
Bone: minimum diameter0.81.44.9-0.01.81.82.21.11.1-1.2-1.2-1.1-1.41.31.10.91.10.91.31.31.1-0.9-1.00.50.6-1.01.0
Time in familiar zone, hab. session 10.20.20.70.1-0.2-0.7-0.8-0.5-0.50.50.30.50.3-0.4-0.3-0.1-0.2-0.0-0.1-0.1-0.1-0.1-0.10.60.6-0.1-0.1
Time in novel zone, hab. session 10.20.10.6-0.00.60.40.40.30.3-0.3-0.3-0.3-0.80.20.40.30.40.30.60.60.2-0.2-0.3-0.1-0.0-0.50.1
Total zone transitions, hab. session 12.73.88.8-1.6-1.8-2.5-3.0-2.1-1.92.02.42.51.3-2.5-1.9-1.7-2.1-1.7-1.8-1.8-2.21.91.9-1.2-1.41.2-0.5
Total locomotion distance, hab. session 12.13.05.4-1.8-1.3-1.9-2.3-1.8-1.71.72.12.30.9-2.2-1.8-1.7-2.0-1.7-1.6-1.6-2.11.81.8-1.3-1.41.0-0.2
Locomotion velocity, hab. session 12.02.95.7-2.0-1.2-1.6-2.2-1.7-1.61.62.12.40.9-2.2-1.8-1.7-2.0-1.7-1.5-1.5-2.11.71.7-1.2-1.30.90.2
Time in familiar zone, hab. session 21.11.14.50.0-1.9-0.7-0.70.10.2-0.10.5-0.20.9-0.4-0.3-0.6-0.6-0.8-1.2-1.2-1.01.41.5-2.1-2.01.3-1.0
Time in novel zone, hab. session 21.41.46.20.31.80.71.0-0.2-0.20.2-0.6-0.2-0.70.60.50.80.81.01.31.31.3-1.6-1.82.52.4-1.20.8
Total zone transitions, hab. session 20.60.83.4-0.5-1.1-1.0-1.8-0.1-0.10.10.70.90.0-1.0-0.5-0.5-0.8-0.6-0.7-0.7-1.21.01.1-1.4-1.40.30.2
Total locomotion distance, hab. session 22.33.16.5-1.3-2.2-1.9-2.6-1.0-1.01.01.81.71.0-1.9-1.4-1.5-1.8-1.6-1.8-1.8-2.22.12.3-2.4-2.41.3-0.3
Locomotion velocity, hab. session 22.83.87.1-1.7-2.2-1.9-2.7-1.2-1.11.12.02.01.0-2.1-1.7-1.8-2.0-1.9-2.0-2.0-2.52.42.5-2.6-2.61.4-0.3
Novel to familiar place preference ratio0.30.31.4-0.10.70.1-0.5-0.1-0.10.0-0.00.7-0.4-0.10.00.30.10.40.50.50.3-0.6-0.71.21.1-0.81.0
Novelty place preference0.20.21.0-0.10.70.1-0.4-0.1-0.00.0-0.00.6-0.4-0.1-0.00.20.00.30.50.50.2-0.5-0.61.01.0-0.80.9
Time in novel zone, NPP test0.20.21.1-0.10.80.3-0.10.10.1-0.1-0.20.4-0.50.10.10.30.20.40.60.60.3-0.6-0.71.01.0-0.70.6
Total zone transitions, NPP test1.72.53.7-1.5-1.3-1.5-1.8-1.5-1.31.41.71.91.1-1.9-1.7-1.7-1.8-1.7-1.6-1.6-1.91.71.7-1.3-1.41.3-1.0
Total locomotion distance, NPP test1.11.62.1-0.8-1.3-1.3-1.4-1.3-1.31.31.31.31.5-1.3-1.4-1.3-1.4-1.3-1.4-1.4-1.31.21.2-0.6-0.71.3-0.8
Locomotion velocity, NPP test1.72.43.8-0.9-1.9-1.7-2.0-1.5-1.41.41.61.51.7-1.6-1.6-1.5-1.6-1.5-1.8-1.8-1.61.61.6-1.0-1.21.5-1.0
Intraocular pressure0.81.22.00.31.41.40.81.21.1-1.2-1.1-0.5-1.41.00.91.00.91.01.31.30.9-1.1-1.10.80.9-1.41.1
Delta distance traveled before/after self-admin0.30.31.20.1-0.7-0.40.3-0.8-0.80.80.40.01.1-0.4-0.5-0.5-0.4-0.5-0.6-0.6-0.10.30.3-0.0-0.10.9-0.8
Delta ambulatory time before/after self-admin0.40.41.40.2-0.9-0.40.3-0.8-0.80.90.4-0.21.0-0.2-0.4-0.5-0.4-0.5-0.6-0.6-0.30.50.5-0.5-0.51.0-1.2
Parametrial fat weight1.83.56.02.11.11.00.32.32.3-2.3-1.7-2.0-2.21.82.42.42.22.32.02.01.8-1.8-1.70.60.9-2.11.5
Pavlov. Cond. lever latency1.82.39.03.0-0.90.50.62.02.0-2.0-1.7-2.60.22.01.81.71.81.60.60.61.7-1.2-1.10.40.5-0.1-0.1
Pavlov. Cond. magazine entry latency1.51.96.8-2.60.5-0.40.3-1.6-1.61.51.51.70.3-1.5-1.7-1.8-1.6-1.7-0.9-0.9-1.61.51.3-0.9-1.10.8-0.8
Pavlov. Cond. change in total contacts0.50.52.7-1.31.60.30.1-0.6-0.70.60.40.9-1.2-0.6-0.2-0.1-0.20.00.80.8-0.1-0.3-0.40.60.6-1.00.6
Pavlov. Cond. index score1.51.98.7-2.91.1-0.2-0.0-1.6-1.61.61.42.4-0.2-1.6-1.7-1.7-1.7-1.5-0.5-0.5-1.61.21.0-0.4-0.50.2-0.0
Pavlov. Cond. latency score1.31.78.3-2.91.2-0.1-0.0-1.5-1.51.41.42.2-0.3-1.6-1.6-1.6-1.6-1.4-0.5-0.5-1.51.10.9-0.4-0.50.10.1
Pavlov. Cond. lever contacts1.51.77.0-2.60.9-0.3-0.4-1.7-1.71.71.42.40.0-1.6-1.7-1.6-1.6-1.4-0.5-0.5-1.40.90.80.1-0.10.10.2
Pavlov. Cond. magazine entry number1.72.15.22.30.10.90.21.61.6-1.5-1.6-1.8-0.61.61.71.81.81.81.21.21.8-1.7-1.61.21.3-1.11.0
Pavlov. Cond. intertrial magazine entries0.40.53.11.2-0.2-0.1-0.1-0.2-0.30.2-0.3-0.30.90.50.20.50.40.50.10.10.9-1.0-1.01.81.7-0.0-0.3
Pavlov. Cond. lever-magazine prob. diff.1.61.98.8-3.01.2-0.2-0.1-1.7-1.71.71.52.5-0.3-1.7-1.7-1.7-1.7-1.5-0.5-0.5-1.51.10.9-0.2-0.30.10.1
Pavlov. Cond. response bias2.32.89.5-3.10.6-0.6-0.1-2.0-2.01.91.82.50.5-1.9-2.2-2.2-2.1-2.0-1.1-1.1-1.91.61.4-0.7-0.90.9-0.7
Pavlov. Cond. lever latency1.72.23.71.51.11.10.61.61.6-1.6-1.5-1.4-1.91.31.91.91.71.81.81.81.4-1.5-1.40.50.7-1.81.2
Pavlov. Cond. magazine entry latency0.50.53.40.11.01.11.90.70.7-0.7-0.7-0.9-0.01.00.30.20.50.30.50.50.8-0.6-0.60.70.7-0.00.0
Pavlov. Cond. change in total contacts0.91.23.0-0.7-1.0-1.0-0.1-1.2-1.21.21.10.61.7-0.8-1.3-1.3-1.1-1.3-1.4-1.4-0.81.01.0-0.3-0.51.6-1.3
Pavlov. Cond. index score0.30.41.1-0.8-0.1-0.10.5-0.7-0.60.70.50.41.0-0.3-0.9-0.9-0.7-0.9-0.8-0.8-0.40.60.50.0-0.11.0-0.7
Pavlov. Cond. latency score0.20.20.6-0.7-0.0-0.00.6-0.4-0.40.40.40.20.8-0.1-0.7-0.7-0.5-0.7-0.6-0.6-0.30.40.40.0-0.10.8-0.5
Pavlov. Cond. lever contacts1.11.53.2-0.7-1.2-1.3-0.9-1.4-1.41.41.31.11.8-1.1-1.5-1.3-1.3-1.3-1.5-1.5-1.01.01.0-0.1-0.31.4-1.1
Pavlov. Cond. magazine entry number0.20.21.4-0.4-0.3-0.5-1.2-0.4-0.40.40.40.8-0.3-0.7-0.2-0.2-0.4-0.2-0.2-0.2-0.60.40.4-0.6-0.5-0.20.2
Pavlov. Cond. intertrial magazine entries0.91.15.6-1.0-0.6-0.60.4-0.7-0.60.71.1-0.1-0.0-0.9-0.3-0.8-0.6-0.9-0.7-0.7-1.11.51.5-2.4-2.31.0-1.4
Pavlov. Cond. lever-magazine prob. diff.0.20.20.7-0.50.00.00.7-0.4-0.40.40.20.10.9-0.0-0.7-0.7-0.5-0.7-0.5-0.5-0.20.30.30.20.10.8-0.6
Pavlov. Cond. response bias0.60.92.0-0.9-0.3-0.60.0-1.1-1.11.10.90.91.4-0.7-1.3-1.2-1.1-1.2-1.0-1.0-0.70.70.60.30.11.2-0.9
Time in closed arm before self-admin0.20.31.0-0.2-0.5-0.70.3-0.7-0.60.60.40.21.0-0.7-0.5-0.5-0.4-0.5-0.5-0.5-0.20.30.30.0-0.00.8-0.3
Time in closed arm after self-admin0.20.21.20.20.4-0.2-0.1-0.2-0.10.2-0.20.50.0-0.4-0.10.20.10.30.40.40.3-0.5-0.51.11.0-0.40.6
Time in open arm before self-admin0.30.31.2-1.10.20.2-0.2-0.5-0.50.50.50.9-0.0-0.4-0.7-0.7-0.7-0.7-0.4-0.4-0.70.60.5-0.3-0.40.20.1
Time in open arm after self-admin1.31.42.2-1.2-0.8-0.20.1-1.3-1.41.30.90.81.3-0.5-1.3-1.5-1.3-1.5-1.5-1.5-1.21.31.3-1.0-1.11.5-1.2
Bone: periosteal estimation1.42.96.40.52.32.32.51.71.6-1.6-1.8-1.5-2.11.81.71.51.71.52.02.01.6-1.5-1.60.80.9-1.71.2
Bone: periosteal perimeter0.50.91.70.41.01.11.31.31.2-1.3-1.0-1.2-1.21.11.10.91.00.81.01.00.8-0.6-0.6-0.10.1-0.80.5
Bone: post-yield work0.30.43.2-0.41.11.11.8-0.1-0.10.1-0.4-0.2-0.40.60.20.20.40.30.50.50.6-0.6-0.70.80.7-0.40.7
Progressive ratio test 1 active lever presses0.30.31.6-0.10.50.40.3-0.4-0.40.4-0.31.20.50.0-0.7-0.5-0.5-0.4-0.1-0.1-0.1-0.1-0.21.10.90.1-0.8
Progressive ratio test 1 breakpoint0.20.31.4-0.10.30.30.1-0.4-0.50.5-0.31.20.5-0.0-0.7-0.5-0.5-0.4-0.2-0.2-0.1-0.1-0.11.00.90.2-0.8
Progressive ratio test 1 inactive lever presses0.70.81.41.10.50.3-0.41.11.0-1.0-1.2-0.3-0.90.50.91.10.91.11.01.00.8-1.0-1.00.80.9-1.10.2
Progressive ratio test 2 active lever presses0.10.10.80.40.0-0.1-0.30.10.0-0.0-0.20.40.1-0.1-0.10.0-0.00.10.20.20.0-0.2-0.10.40.4-0.1-0.9
Progressive ratio test 2 breakpoint0.10.10.90.3-0.1-0.3-0.6-0.0-0.10.1-0.00.60.1-0.3-0.2-0.0-0.1-0.00.20.2-0.1-0.0-0.00.30.3-0.1-0.9
Progressive ratio test 2 inactive lever presses0.20.21.1-0.80.60.20.4-0.4-0.40.40.21.00.0-0.6-0.6-0.6-0.5-0.5-0.1-0.1-0.40.20.20.20.20.1-0.3
Incentive Sensitization - Responses0.80.82.4-0.0-1.2-1.3-1.5-0.3-0.30.31.00.50.4-1.1-0.5-0.6-0.7-0.7-0.7-0.7-1.11.01.1-1.3-1.30.7-1.1
Incentive Sensitization - Breakpoint0.50.52.20.2-1.0-1.1-1.50.0-0.0-0.00.80.20.1-0.8-0.2-0.3-0.4-0.4-0.4-0.4-0.80.80.9-1.2-1.20.4-1.0
Sum of active levers in priming session hrs 5-60.50.51.4-1.00.1-0.20.1-1.2-1.21.20.61.00.7-0.5-1.0-0.9-0.9-0.8-0.6-0.6-0.50.40.30.40.30.50.1
Progressive ratio3.84.49.23.01.01.50.62.62.5-2.5-2.3-2.4-2.02.32.62.52.52.42.12.02.1-2.0-1.90.81.1-1.90.9
Food seeking constrained by brief footshock0.10.10.80.4-0.4-0.20.20.30.2-0.4-0.30.00.9-0.0-0.2-0.1-0.0-0.0-0.10.10.3-0.2-0.20.80.70.40.6
Seeking ratio, punishment vs. effort2.32.85.7-2.4-1.0-1.4-0.8-2.0-1.91.91.72.11.8-2.0-2.2-2.0-2.1-1.9-1.7-1.5-1.71.61.5-0.5-0.71.6-0.4
Retroperitoneal fat weight1.13.75.31.61.81.71.22.22.3-2.2-2.0-1.4-1.72.21.81.91.92.02.12.12.0-2.1-2.11.92.0-1.91.6
Reaction time number correct0.91.34.32.1-0.20.2-0.41.51.6-1.6-1.1-1.3-0.71.11.41.51.31.50.90.91.1-1.2-1.00.70.8-1.00.5
Reaction time mean minus median0.50.74.5-1.61.71.62.10.50.4-0.5-0.4-0.3-1.20.50.2-0.20.1-0.20.50.50.00.20.0-0.6-0.5-0.30.6
Reaction time mean minus median AUC0.50.76.2-1.71.81.52.50.0-0.00.0-0.3-0.3-0.70.4-0.1-0.40.1-0.30.30.30.3-0.1-0.20.20.2-0.10.9
Reaction time num false alarms0.30.42.5-0.90.20.3-0.00.30.3-0.30.40.2-0.6-0.3-0.2-0.5-0.4-0.6-0.3-0.3-0.80.90.9-1.6-1.50.1-0.2
Reaction time num false alarms AUC0.71.04.3-1.3-0.4-0.2-0.3-0.1-0.10.10.90.6-0.1-0.8-0.7-1.0-1.0-1.1-0.8-0.8-1.41.51.5-2.1-2.00.6-0.4
Reaction time trials correct on left0.91.34.32.1-0.20.2-0.41.51.6-1.6-1.1-1.3-0.71.11.41.51.31.50.90.91.1-1.2-1.00.70.8-1.00.5
Reaction time trials on left0.91.34.12.0-0.20.3-0.31.51.6-1.6-1.1-1.3-0.71.11.41.51.31.40.80.81.2-1.1-1.00.60.8-1.00.5
Reaction time mean0.40.66.1-1.21.31.22.50.10.1-0.1-0.1-0.8-0.40.50.2-0.00.40.00.40.40.6-0.3-0.40.20.2-0.11.1
Reaction time mean AUC0.70.97.4-0.91.61.52.70.40.4-0.4-0.4-1.1-0.60.80.50.30.70.40.70.70.9-0.6-0.80.60.6-0.31.4
Median of all reaction times0.30.54.3-0.60.90.92.10.20.2-0.2-0.1-1.0-0.30.50.50.20.50.30.40.40.7-0.4-0.50.30.4-0.11.1
Reaction time omissions0.20.31.6-0.60.50.31.30.60.7-0.80.2-0.8-0.70.30.40.00.3-0.00.20.20.00.30.3-1.0-0.90.00.6
Reaction time false alarm rate1.62.35.9-2.4-0.2-0.3-0.2-1.1-1.11.11.51.40.3-1.5-1.6-1.8-1.7-1.9-1.2-1.2-2.02.01.9-2.1-2.11.1-0.6
Reaction time premature initiation rate0.10.20.8-0.1-0.5-0.9-0.4-0.5-0.50.50.60.10.4-0.5-0.2-0.2-0.2-0.2-0.4-0.4-0.20.30.3-0.3-0.30.30.3
Reaction time premature initiations0.20.31.41.2-0.5-0.5-0.40.50.5-0.5-0.2-0.7-0.10.30.80.80.70.80.30.30.6-0.6-0.50.30.4-0.40.7
Std. dev. reaction times0.50.76.5-1.91.61.52.60.10.1-0.1-0.1-0.3-0.60.4-0.2-0.5-0.1-0.50.20.2-0.00.30.2-0.5-0.50.10.6
Reaction time trials completed0.91.34.12.0-0.20.3-0.31.51.6-1.6-1.1-1.3-0.71.11.41.51.31.40.80.81.2-1.1-1.00.60.8-1.00.5
Reaction time trials AUC1.01.44.32.1-0.20.3-0.31.61.6-1.6-1.1-1.4-0.61.11.41.51.41.50.80.81.2-1.2-1.00.60.7-1.00.5
Run reversals in cocaine runway, females0.40.42.70.20.60.60.4-0.6-0.60.6-0.30.60.20.6-0.20.10.10.30.20.20.5-0.8-0.91.61.5-0.40.2
Run reversals in cocaine runway, males0.50.52.9-1.71.71.20.90.10.3-0.3-0.10.6-1.3-0.0-0.0-0.2-0.1-0.10.50.5-0.1-0.0-0.1-0.0-0.0-0.81.0
Latency to leave start box in cocaine runway0.60.72.0-0.4-0.8-1.4-0.9-1.0-0.90.91.10.50.8-1.4-0.7-0.7-0.7-0.7-0.7-0.7-0.70.70.7-0.4-0.50.8-0.8
Latency to leave start box in cocaine runway, F0.50.50.7-0.2-0.8-0.8-0.8-0.7-0.60.70.70.40.8-0.8-0.7-0.7-0.7-0.7-0.8-0.8-0.70.80.8-0.6-0.60.8-0.6
Latency to leave start box in cocaine runway, M0.20.21.3-0.3-0.3-1.1-1.1-0.4-0.40.30.80.5-0.1-1.0-0.1-0.0-0.20.00.10.1-0.30.10.1-0.0-0.1-0.2-0.1
Std. dev. time between licks in bursts0.91.15.9-2.41.41.20.60.20.2-0.20.01.0-1.6-0.5-0.5-0.8-0.7-0.80.20.2-1.21.11.0-1.7-1.6-0.40.8
Total sessions with >9 infusions0.20.31.1-0.50.70.60.6-0.5-0.50.5-0.21.00.20.0-0.6-0.4-0.3-0.30.10.10.0-0.2-0.31.00.9-0.0-0.7
Short access day 1 total inactive lever presses0.30.31.3-1.10.90.70.8-0.6-0.60.60.01.00.1-0.4-0.7-0.6-0.5-0.5-0.2-0.2-0.20.1-0.00.60.50.00.3
Short access day 10 total inactive lever presses1.01.16.10.6-1.0-0.8-1.61.31.4-1.40.1-1.3-1.1-0.41.00.60.50.40.10.1-0.40.70.8-2.5-2.2-0.2-0.4
Short access day 1 total infusions1.41.55.9-1.70.3-0.10.0-1.7-1.81.70.92.41.0-1.1-1.8-1.6-1.6-1.5-1.0-1.0-1.20.80.70.40.20.7-0.4
Short access day 10 total infusions0.00.00.3-0.20.10.40.00.10.0-0.0-0.60.30.10.1-0.1-0.1-0.1-0.10.10.1-0.0-0.0-0.00.20.20.0-0.2
Short access total infusions0.30.41.6-0.80.80.70.4-0.7-0.80.8-0.31.30.1-0.0-0.7-0.4-0.5-0.30.10.1-0.1-0.2-0.31.11.0-0.2-0.1
Short access day 1 locomotion0.30.31.1-0.2-0.3-0.4-1.10.0-0.0-0.00.30.8-0.0-0.5-0.5-0.5-0.6-0.5-0.3-0.3-0.80.70.7-0.8-0.80.2-0.8
Short access day 10 total locomotion0.60.72.9-0.5-0.50.0-0.50.40.4-0.40.10.40.1-0.2-0.5-0.8-0.7-0.9-0.7-0.7-1.01.21.2-1.7-1.60.8-1.1
Short access total locomotion0.10.10.5-0.10.10.50.30.60.5-0.5-0.5-0.1-0.10.40.1-0.00.1-0.10.10.10.00.10.1-0.3-0.30.1-0.7
One hour access (0.3 mA shock)0.80.91.6-1.3-0.6-0.6-1.1-0.8-0.90.80.71.10.5-0.9-1.0-1.0-1.1-1.0-0.9-0.9-1.21.11.1-0.9-1.00.7-0.8
Compulsive drug intake2.12.13.5-1.0-1.7-1.0-0.8-1.5-1.51.41.10.41.7-1.1-1.4-1.5-1.4-1.5-1.9-1.9-1.41.61.6-1.5-1.61.8-1.0
One hour access (shock baseline)0.40.41.9-0.61.41.11.00.20.1-0.2-0.70.5-0.60.60.00.10.20.20.80.80.4-0.6-0.71.01.0-0.70.2
Social response proportion0.00.00.2-0.30.10.10.4-0.00.1-0.10.10.00.00.1-0.2-0.2-0.2-0.2-0.1-0.1-0.10.20.2-0.3-0.30.20.1
Social responses0.20.31.5-0.1-0.6-0.5-0.40.30.3-0.30.5-0.20.1-0.1-0.0-0.2-0.2-0.3-0.5-0.5-0.50.70.7-1.2-1.10.4-0.4
Social time0.81.07.2-1.1-0.3-0.20.2-0.1-0.00.01.0-0.2-0.6-0.6-0.1-0.6-0.5-0.8-0.5-0.5-1.11.41.4-2.7-2.50.6-0.6
Soleus weight0.61.78.4-2.72.82.52.90.60.7-0.6-0.6-0.0-1.90.50.0-0.5-0.1-0.50.80.8-0.30.50.3-1.1-1.0-0.60.7
Bone: stiffness0.81.32.01.40.80.70.60.90.9-0.9-1.0-0.9-1.11.11.31.41.31.41.31.31.3-1.4-1.31.01.1-1.30.6
Tibialis anterior weight0.72.34.5-0.5-2.0-2.1-1.1-1.4-1.51.41.60.71.7-1.4-1.2-1.3-1.3-1.4-1.7-1.7-1.41.61.7-1.5-1.61.8-1.7
Time to tail flick, vehicle, before self-admin1.92.05.71.00.70.3-0.02.01.9-1.9-0.7-2.0-2.40.62.11.71.61.61.61.60.8-0.7-0.6-1.0-0.7-1.60.8
Time to tail flick, vehicle, after self-admin0.20.20.80.3-0.9-0.8-0.4-0.1-0.10.10.5-0.30.5-0.20.0-0.1-0.1-0.2-0.4-0.4-0.20.40.4-0.7-0.60.6-0.7
Time to tail flick, test, before self-admin0.40.42.50.4-0.9-0.9-1.60.90.9-1.00.10.0-0.3-0.60.20.1-0.00.0-0.2-0.2-0.50.50.6-1.1-1.0-0.10.1
Time to tail flick, test, after self-admin0.10.10.9-0.10.2-0.5-0.2-0.1-0.00.00.40.2-0.5-0.70.1-0.0-0.0-0.10.20.2-0.30.30.3-0.5-0.5-0.2-1.0
Delta time to tail flick, vehicle, before/after SA1.31.34.5-0.5-0.9-0.8-0.3-1.7-1.61.70.71.42.1-0.5-1.5-1.2-1.2-1.1-1.3-1.3-0.50.40.41.00.71.3-0.8
Delta time to tail flick, test, before/after SA0.80.71.30.91.10.50.90.20.2-0.2-0.4-0.8-0.90.60.91.01.01.01.11.11.1-1.1-1.11.01.0-0.9-0.4
Tibia length2.46.813.10.83.23.63.32.93.0-2.9-2.9-2.4-3.32.82.72.32.62.43.03.02.3-2.2-2.20.91.2-2.61.9
Ambulatory time before self-admin0.70.72.40.40.30.8-0.11.51.5-1.5-1.0-0.8-1.20.90.90.80.70.70.70.70.3-0.2-0.2-0.6-0.5-0.70.9
Ambulatory time after self-admin0.40.42.00.7-0.60.50.20.90.9-0.8-0.7-1.0-0.10.80.50.20.30.1-0.1-0.1-0.00.40.5-1.4-1.30.4-0.2
Bone: tissue strength0.10.10.70.7-0.3-0.1-0.10.10.1-0.1-0.3-0.10.60.30.00.20.20.2-0.1-0.10.4-0.5-0.40.80.80.1-0.0
Total heroin consumption0.20.20.7-0.2-0.70.20.3-0.2-0.30.30.1-0.60.50.5-0.1-0.3-0.2-0.4-0.4-0.4-0.30.50.5-0.9-0.80.7-0.0
Bone: trabecular number0.71.11.9-0.5-1.2-1.2-0.9-1.3-1.31.21.21.11.4-1.1-1.1-1.0-1.1-1.0-1.2-1.2-0.90.80.8-0.2-0.31.1-0.7
Bone: trabecular spacing1.62.13.11.11.31.61.31.71.7-1.7-1.7-1.6-1.51.61.61.51.61.51.51.51.5-1.3-1.30.70.8-1.31.1
Bone: trabecular thickness0.40.41.30.01.01.00.70.30.2-0.3-0.6-0.0-0.50.60.30.40.40.50.70.70.7-0.8-0.91.11.1-0.70.7
Bone: trabecular tissue density0.20.31.5-1.01.21.10.60.30.3-0.4-0.50.6-0.70.3-0.2-0.2-0.2-0.10.30.3-0.1-0.1-0.20.30.3-0.50.9
Water consumed over 24 hours1.01.22.8-0.2-1.4-1.3-0.1-1.1-1.21.21.00.11.6-0.7-0.9-1.0-0.8-1.0-1.3-1.3-0.71.01.0-0.8-0.81.6-1.7
Number of responses in last shaping day2.42.57.9-2.70.6-0.30.1-2.4-2.32.31.42.80.9-1.6-2.2-2.0-2.0-1.7-1.0-1.0-1.41.00.80.60.30.7-0.3