Hub : Genes

Acsl5

acyl-CoA synthetase long-chain family member 5

chr1:264294851–264341943 (+)

Acsl5 RatGTEx page

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 NAcc gene expression Acsl5 0.08 0.06 2.0e-08 0.04 0.05 0.06 0.06 1.7e-06 6.0e-08 4.1e-09 9.1e-09
2 Liver gene expression Acsl5 0.05 0.04 2.3e-05 0.04 0.03 0.04 0.03 4.7e-05 1.5e-04 6.4e-05 1.0e-04
3 pVTA gene expression Acsl5 0.03 0.02 9.0e-03 0.03 0.02 0.02 0.02 2.5e-03 1.0e-02 6.5e-03 6.4e-03
4 Adipose gene expression Acsl5 0.02 0.02 5.7e-03 0.02 0.01 0.02 0.02 2.5e-03 1.5e-02 1.2e-03 1.5e-03
5 OFC gene expression Acsl5 0.28 0.16 2.2e-05 0.17 0.17 0.15 0.14 7.0e-05 7.0e-05 2.4e-04 3.7e-04
6 Liver mRNA stability Acsl5 0.07 0.05 2.6e-09 0.06 0.07 0.07 0.06 1.3e-07 2.9e-08 3.7e-08 1.0e-07
7 PL mRNA stability Acsl5 0.04 0.03 4.5e-03 0.02 0.02 0.01 0.02 1.2e-03 5.9e-03 2.2e-02 4.2e-03
8 IC intron excision ratio chr1_264299839_264315405 0.07 0.06 5.8e-03 0.04 0.02 0.04 0.04 1.1e-02 3.7e-02 5.8e-03 1.0e-02
9 IC mRNA stability Acsl5 0.08 0.06 3.0e-03 0.05 0.04 0.02 0.03 4.0e-03 6.5e-03 4.6e-02 1.7e-02
10 NAcc intron excision ratio chr1_264299839_264315405 0.02 0.02 1.7e-03 0.02 0.02 0.01 0.01 9.1e-04 1.3e-03 2.3e-03 2.3e-03
11 pVTA mRNA stability Acsl5 0.08 0.06 3.2e-05 0.06 0.06 0.05 0.06 3.2e-05 3.1e-05 3.4e-05 2.4e-05
12 PL intron excision ratio chr1_264299839_264315405 0.04 0.03 4.2e-03 0.01 0.02 0.02 0.01 8.9e-03 4.8e-03 3.2e-03 2.3e-02
13 PL isoform ratio XM_039093168.2 0.46 0.21 5.0e-03 -0 0.01 0.01 0.01 3.9e-01 5.2e-02 1.2e-02 5.1e-02

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13
Bone: apparent density1.72.96.62.61.92.11.7-1.71.3-2.02.0-1.81.80.6-0.21.0
Area under the delay curve0.81.02.01.10.81.10.4-0.60.3-1.41.4-1.41.4-0.40.81.0
BMI with tail7.124.350.67.07.16.86.8-6.76.3-2.01.8-1.92.24.1-2.8-0.7
BMI without tail3.711.326.34.55.14.74.7-4.64.3-1.21.1-1.31.52.2-1.71.6
Body weight7.733.969.78.48.38.27.8-7.97.3-2.82.6-2.73.14.6-2.50.6
Weight adjusted by age3.35.010.32.43.02.93.2-2.82.90.5-0.50.0-0.21.9-3.21.0
Bone surface0.61.12.71.61.51.31.5-1.11.0-0.60.6-0.90.60.8-0.60.3
Bone volume2.34.19.73.12.72.72.6-2.52.2-1.51.4-1.61.31.5-0.90.2
Breakpoint value in progressive ratio session1.11.43.50.90.80.80.2-0.4-0.0-1.71.7-1.91.7-0.81.10.9
Number of licking bursts0.71.23.30.91.00.60.2-0.3-0.0-1.71.7-1.61.8-0.51.00.2
Context. condit. distance diff. score0.60.72.0-0.8-0.5-0.6-0.20.5-0.11.1-1.01.3-1.2-0.1-1.01.4
Locomotion velocity, session 11.71.84.2-1.6-1.6-1.8-2.11.9-2.0-0.60.7-0.40.5-1.4-0.20.0
Locomotion distance, session 10.30.41.0-0.8-0.7-0.8-0.50.6-0.40.5-0.51.0-0.7-0.0-0.80.5
Locomotion velocity, session 21.41.63.9-1.0-1.1-1.1-0.30.7-0.31.7-1.72.0-1.90.6-1.7-0.1
Locomotion distance, session 21.01.32.51.61.51.51.4-1.61.5-0.60.6-0.10.61.1-1.20.5
Locomotion velocity, session 30.30.32.4-0.00.0-0.10.10.00.10.3-0.30.7-0.00.0-0.91.5
Locomotion distance, session 30.80.95.20.10.30.30.6-0.50.80.7-0.71.5-0.70.5-2.31.2
Stereotopy head waving bouts, day 30.20.31.40.30.30.3-0.0-0.30.2-0.50.5-0.40.60.1-0.8-1.2
Stereotopy head waving duration, day 30.70.81.6-0.9-0.8-1.1-1.31.1-1.3-0.60.6-0.60.7-1.10.5-0.7
Locomotion velocity, session 70.20.21.60.40.10.30.3-0.10.1-0.40.4-0.40.4-0.1-0.31.3
Locomotion distance, session 70.20.31.6-0.1-0.3-0.10.10.10.10.5-0.50.8-0.60.3-0.41.3
Stereotopy head waving bouts, day 70.10.10.30.20.40.10.1-0.10.0-0.40.4-0.40.5-0.10.2-0.5
Stereotopy head waving duration, day 70.40.51.20.61.00.40.4-0.40.2-0.90.8-1.01.1-0.10.9-0.5
Locomotion velocity, session 80.91.12.6-1.3-1.5-1.6-1.21.4-1.20.9-0.81.0-0.7-0.20.0-0.2
Locomotion distance, session 80.40.73.0-0.4-0.3-0.40.10.20.10.9-0.91.3-1.00.2-0.91.7
Degree of sensitization distance0.90.94.3-0.6-0.9-0.9-0.91.1-1.3-0.40.4-1.00.4-0.82.10.1
Degree of sensitization stereotypy0.20.20.70.30.50.30.1-0.20.0-0.70.7-0.80.8-0.30.50.3
Conditioned locomotion0.10.10.2-0.0-0.3-0.2-0.10.00.10.3-0.30.2-0.20.3-0.3-0.4
Cocaine response after cond. corrected1.21.42.9-1.7-1.2-1.2-1.01.1-0.81.4-1.31.2-1.3-0.8-0.21.5
Cocaine response after cond. not corrected1.82.14.6-2.1-1.8-1.7-1.61.6-1.41.4-1.41.3-1.3-1.00.40.8
Cocaine response before conditioning0.60.72.3-0.5-0.8-0.8-0.91.0-1.0-0.30.4-0.40.5-0.41.1-1.5
Saline control response0.71.01.8-1.2-1.3-1.3-1.01.1-0.90.9-0.91.3-1.2-0.2-0.0-0.4
Bone: connectivity density0.10.11.40.3-0.20.00.30.2-0.2-0.20.2-0.20.2-0.1-0.11.2
Bone: cortical apparent density3.14.310.8-2.0-1.7-1.6-0.51.1-0.43.2-3.23.3-3.20.6-1.5-0.2
Bone: cortical area4.77.216.13.74.03.43.2-3.22.7-2.32.2-2.52.21.2-0.71.5
Bone: cortical porosity0.50.51.60.4-0.10.1-0.20.1-0.3-1.11.1-1.01.3-0.60.40.9
Bone: cortical porosity1.11.13.30.90.40.60.1-0.40.0-1.61.6-1.61.8-0.60.61.2
Bone: cortical thickness2.33.88.02.72.82.52.6-2.52.3-1.11.0-1.10.91.4-1.01.5
Bone: cortical thickness1.61.93.51.71.91.61.9-1.81.8-0.10.1-0.00.11.8-1.3-0.6
Bone: cortical tissue density3.34.410.9-2.2-1.8-1.7-0.61.3-0.63.2-3.23.3-3.20.6-1.4-0.3
Condit. Reinf. active minus inactive responses0.80.93.3-0.8-0.3-0.4-0.90.6-0.7-0.80.8-0.20.7-1.5-1.21.8
Condit. Reinf. active-inactive response ratio0.80.92.5-1.2-0.7-0.8-1.11.0-1.0-0.40.40.00.3-1.6-0.91.5
Condit. Reinf. active responses1.01.23.10.10.40.5-0.3-0.2-0.1-1.71.7-0.91.6-1.2-1.41.8
Condit. Reinf. inactive responses1.11.33.71.00.81.00.3-0.70.4-1.91.9-1.41.9-0.5-0.40.8
Incentive salience index mean1.11.33.6-1.4-1.0-0.9-1.41.2-1.2-0.60.7-0.00.6-1.9-0.91.7
Condit. Reinf. lever presses0.70.92.0-1.2-1.2-1.0-1.41.2-1.3-0.50.5-0.10.6-1.4-0.00.6
Condit. Reinf. active minus inactive responses3.24.29.5-0.80.4-0.6-1.51.1-1.7-2.72.8-2.52.4-3.11.32.9
Condit. Reinf. active-inactive response ratio2.52.98.5-1.4-0.1-1.0-1.71.4-1.8-1.71.8-1.61.5-2.91.32.5
Condit. Reinf. active responses2.83.99.40.31.00.3-0.60.3-1.0-3.03.1-2.82.8-2.40.92.7
Condit. Reinf. inactive responses0.91.12.51.10.70.90.5-0.50.2-1.51.5-1.51.6-0.40.01.4
Condit. Reinf. lever presses1.31.74.40.10.50.1-0.50.4-0.8-2.12.1-2.01.7-1.80.81.5
Condit. Reinf. lever reinforcers received2.63.78.50.10.80.2-0.70.4-1.1-2.92.9-2.72.5-2.50.92.8
Conditioned reinforcement - actives0.40.61.7-0.2-0.10.0-0.50.3-0.6-1.11.1-1.00.9-1.10.41.3
Conditioned reinforcement - inactives0.50.81.60.80.81.00.5-0.60.4-1.21.2-1.21.2-0.5-0.51.0
Conditioned locomotion0.30.52.50.3-0.1-0.10.4-0.10.30.6-0.60.6-0.70.90.8-1.6
Patch foraging indifference point 0 sec1.62.95.92.32.42.42.1-2.32.1-1.01.0-1.01.11.0-1.00.4
Patch foraging indifference point AUC1.01.54.01.20.40.8-0.0-0.3-0.1-2.01.9-2.02.00.00.4-1.1
Delay disc. indifference point, 0s delay1.01.13.41.81.21.31.6-1.21.1-0.50.5-0.70.60.90.10.3
Delay disc. indifference point, 16s delay0.60.61.60.20.10.4-0.40.1-0.4-1.11.1-1.31.1-0.81.10.6
Delay disc. indifference point, 2s delay0.10.10.60.40.10.20.3-0.20.2-0.10.00.10.00.40.8-0.5
Delay disc. indifference point, 24s delay1.51.74.40.70.70.9-0.5-0.3-0.2-2.02.0-2.02.1-0.71.50.2
Delay disc. indifference point, 4s delay0.60.64.10.10.20.3-0.3-0.0-0.2-0.80.8-0.80.9-0.80.72.0
Delay disc. indifference point, 8s delay2.22.64.72.21.92.11.4-1.51.0-1.91.9-1.81.90.00.51.0
Indifference point function ln k0.40.62.8-0.9-0.4-0.8-0.40.5-0.20.9-0.91.0-0.9-0.30.31.7
Indifference point function log k0.40.62.8-0.9-0.4-0.8-0.40.5-0.20.9-0.91.0-0.9-0.30.31.7
Patch foraging total patch changes 0 sec1.62.95.72.42.42.42.0-2.32.0-1.31.2-1.21.30.9-0.80.2
Patch foraging total patch changes 12 sec1.21.53.41.51.11.40.6-1.00.7-1.81.8-1.61.8-0.0-0.00.5
Patch foraging total patch changes 18 sec2.64.08.62.51.92.11.1-1.71.1-2.92.9-2.72.90.30.20.0
Patch foraging total patch changes 24 sec1.93.310.11.81.01.60.5-0.90.4-2.82.7-2.93.2-0.70.80.2
Patch foraging total patch changes 6 sec2.74.18.02.82.82.72.2-2.52.2-1.81.8-1.81.81.0-0.90.3
Patch foraging time to switch 0 sec0.51.12.2-1.5-1.1-1.3-0.81.0-0.71.2-1.11.2-1.1-0.50.61.0
Patch foraging water rate 0 sec0.40.92.21.51.01.20.9-1.00.9-1.01.0-0.70.70.6-1.0-0.7
Patch foraging water rate 12 sec0.51.01.91.31.41.20.8-1.10.9-1.11.1-1.00.90.3-0.6-0.2
Patch foraging water rate 18 sec0.40.61.70.91.30.91.1-1.01.00.0-0.10.2-0.10.7-0.90.0
Patch foraging water rate 24 sec1.72.45.52.32.42.11.9-1.91.7-1.11.1-0.90.90.9-0.90.6
Patch foraging water rate 6 sec0.71.04.00.91.00.40.9-0.70.90.2-0.20.8-0.51.4-1.1-2.0
Seeking ratio, delayed vs. immediate footshock0.10.10.6-0.2-0.3-0.5-0.30.3-0.20.2-0.20.30.10.40.8-0.4
Distance traveled before self-admin2.43.18.0-0.8-0.6-0.60.60.10.52.8-2.82.7-2.81.5-2.1-0.9
Distance traveled after self-admin2.12.55.10.50.40.51.5-0.81.32.2-2.31.9-2.22.1-1.5-1.6
Extensor digitorum longus weight0.41.63.31.81.21.61.2-1.51.3-1.31.2-1.11.50.8-0.80.2
Bone: elastic displacement0.40.44.50.1-0.00.30.1-0.10.0-0.50.5-0.40.4-0.60.22.1
Bone: elastic work1.21.53.11.31.21.41.8-1.61.70.6-0.60.6-0.61.4-1.11.1
Bone: endosteal estimation1.43.26.42.52.52.32.0-2.01.6-1.61.6-1.91.70.8-0.4-0.1
Bone: endosteal perimeter2.14.411.53.03.42.62.8-2.52.2-1.51.4-1.71.41.3-0.7-0.5
Epididymis fat weight7.224.547.26.96.86.75.8-6.05.1-4.24.1-4.44.52.2-1.62.0
Delta time in closed arm before/after self-admin1.11.03.9-0.20.10.20.5-0.40.61.1-1.11.1-1.11.3-2.0-1.5
Delta time in open arm before/after self-admin1.11.12.61.21.01.00.6-0.60.2-1.21.2-1.61.3-0.31.60.8
Diff in mean of infusions in LGA sessions1.21.43.5-1.9-1.4-1.4-1.61.4-1.30.1-0.10.2-0.1-1.5-0.41.5
Delay discount exponential model param1.01.12.2-1.0-0.9-1.1-0.30.6-0.31.4-1.41.4-1.50.4-0.9-1.0
Extinction: sum of active levers before priming1.11.23.0-0.1-0.4-0.3-0.90.6-1.0-1.41.5-1.51.5-1.01.70.4
Active lever presses in extinction session 60.40.41.10.90.70.70.6-0.50.4-0.40.4-0.60.50.60.6-1.0
Bone: final force1.11.84.51.92.11.61.8-1.61.4-0.90.8-0.80.91.1-1.0-0.6
Bone: final moment1.52.55.72.32.42.02.0-1.91.7-1.11.1-1.01.11.2-1.0-0.3
Food consumed during 24 hour testing period0.30.42.70.10.30.10.2-0.10.2-0.20.20.5-0.1-0.2-1.21.6
Glucose1.21.93.81.71.51.61.9-1.82.00.3-0.40.5-0.51.8-1.1-1.3
Heart weight2.13.27.12.02.32.32.1-2.01.8-1.01.0-0.91.00.2-2.22.7
Delay discount hyperbolic model param0.70.81.5-0.9-0.8-1.0-0.30.6-0.41.2-1.21.2-1.20.2-0.6-1.0
Intermittent access intake day 1-15 change0.91.93.51.81.91.91.6-1.71.5-1.11.0-1.01.10.6-1.00.7
Intermittent access intake escalation0.91.93.61.91.91.91.6-1.71.5-1.11.1-1.11.20.6-1.10.7
Intermittent access intake escalation 20.91.02.11.41.31.41.2-1.21.0-0.80.8-0.90.90.5-0.50.4
Intermitt. access day 1 inactive lever presses0.82.85.22.21.82.11.2-1.40.9-2.22.2-2.22.3-0.20.80.3
Intermitt. access day 15 inactive lever presses0.20.41.40.10.40.50.1-0.1-0.1-0.70.7-0.90.9-0.8-0.01.2
Intermitt. access escalation Index0.30.41.50.70.30.20.6-0.50.60.4-0.40.7-0.61.1-0.3-1.2
Intermittent access day 1 total infusions0.40.72.10.80.60.50.1-0.3-0.0-1.41.4-1.21.1-0.60.40.8
Intermittent access day 15 total infusions1.01.42.71.31.21.20.8-0.90.6-1.51.5-1.41.5-0.4-0.61.6
Intermittent access terminal intake (last 3 days)0.50.61.10.90.80.80.6-0.60.4-1.01.0-1.01.0-0.2-0.11.0
Intermittent access total infusions1.01.12.31.31.11.00.7-0.70.4-1.51.5-1.41.5-0.30.30.8
Intermittent access day 1 locomotion0.30.40.90.30.50.20.7-0.50.60.7-0.70.6-0.70.7-0.90.2
Intermittent access day 15 total locomotion1.01.83.92.01.91.92.0-1.71.6-0.40.3-0.80.71.0-0.70.7
Intermittent access total locomotion0.70.91.90.90.90.71.4-1.01.20.9-0.90.6-0.61.4-0.8-0.1
Intermittent access standard deviation0.51.12.81.21.11.00.5-0.80.4-1.71.7-1.41.5-0.30.30.3
Left kidney weight2.210.122.84.03.63.94.8-4.24.50.9-1.01.1-0.73.7-3.1-0.1
Right kidney weight2.913.027.04.54.34.65.2-4.85.00.2-0.30.5-0.23.5-4.60.9
Cocaine induced anxiety1.82.64.7-2.0-1.9-1.8-1.21.5-1.12.2-2.11.9-2.00.30.3-1.0
Post-drug Anxiety0.10.10.6-0.1-0.20.00.00.1-0.10.5-0.50.2-0.40.20.8-0.3
Baseline Anxiety2.52.96.32.01.71.80.9-1.30.7-2.52.5-2.22.4-0.40.70.6
Tail length0.31.48.81.01.11.20.9-1.00.9-0.60.6-0.80.9-0.20.53.0
Length with tail1.35.611.53.43.13.33.0-3.22.9-1.21.1-1.31.31.8-0.11.8
Length without tail3.611.527.35.24.34.74.2-4.43.9-2.42.3-2.32.42.8-0.0-0.2
LgA early post infusion interval0.20.31.0-0.5-0.3-1.0-0.80.6-0.6-0.30.30.10.4-0.30.9-0.3
LgA late post infusion interval1.31.65.6-0.3-0.8-0.8-1.40.9-1.2-1.51.6-1.31.4-0.92.4-0.4
LgA early loading0.91.73.9-0.7-0.30.1-1.40.7-1.1-1.71.8-1.71.6-1.60.32.0
LgA late loading0.30.73.70.20.80.70.5-0.60.6-0.20.2-0.10.2-0.0-1.91.6
LgA early average infusions1.01.34.0-1.0-1.2-0.3-1.31.1-1.3-0.90.9-0.90.8-1.70.22.0
LgA late average infusions0.81.23.71.01.51.51.3-1.31.2-0.60.5-0.40.60.3-1.90.9
LgA early timeout0.20.30.70.40.30.80.2-0.40.2-0.60.6-0.80.6-0.0-0.20.5
LgA late timeout1.31.75.31.11.21.51.7-1.31.50.7-0.80.6-0.51.6-2.3-0.7
LgA early titration0.40.62.0-0.1-0.60.4-0.50.5-0.6-0.80.8-1.10.8-1.00.81.4
LgA late titration0.91.42.91.41.41.71.5-1.51.4-0.70.6-0.50.70.5-1.60.6
LgA total infusion0.40.61.20.80.71.10.8-0.70.6-0.80.7-0.90.8-0.2-0.80.9
Times rat made contact with spout1.11.23.41.81.31.41.3-1.51.4-0.80.8-0.30.61.0-0.60.0
Lifetime Intake1.11.42.81.31.21.10.7-0.80.4-1.71.7-1.61.6-0.40.51.1
Liver weight, left3.25.311.43.43.43.13.2-3.02.7-1.31.2-1.71.51.6-0.2-0.2
Liver weight, right5.69.819.94.54.14.04.4-4.34.3-0.50.3-0.50.53.5-1.6-1.7
Locomotor activity1.11.73.61.11.30.91.7-1.31.51.1-1.10.8-0.61.6-1.9-1.3
Locomotor testing distance1.52.74.40.91.20.92.0-1.31.72.0-2.01.6-1.52.1-2.1-1.5
Locomotor testing rearing0.71.43.11.01.21.11.8-1.31.51.3-1.30.8-0.81.3-1.0-0.5
Locomotion in novel chamber1.21.64.3-0.10.10.00.9-0.50.91.9-2.02.1-2.01.2-1.2-0.1
Locomotion in novel chamber post-restriction0.61.02.5-1.3-1.6-1.2-1.11.2-1.00.6-0.70.8-0.9-0.6-0.81.0
Fecal boli incidents, locomotor time 10.20.21.90.1-0.2-0.00.10.3-0.4-0.30.4-0.50.5-0.31.4-0.1
Change in fecal boli incidents, locomotor task0.40.41.6-0.9-0.4-0.3-0.70.3-0.30.4-0.3-0.20.1-0.5-1.31.1
Time >=10cm from walls, locomotor time 10.60.71.9-0.8-1.4-1.1-0.81.0-0.90.5-0.50.5-0.5-0.31.0-0.4
Bouts of movement, locomotor time 11.92.24.71.91.41.71.2-0.90.4-2.02.0-2.22.2-0.40.40.5
Total resting periods, locomotor time 11.71.83.81.51.41.70.7-0.90.5-1.92.0-1.91.9-0.30.20.3
Rest time, locomotor task time 10.30.41.40.30.91.00.2-0.70.7-0.20.1-0.20.10.3-1.20.0
Distance moved, locomotor task time 10.10.10.40.2-0.2-0.10.2-0.00.10.2-0.20.4-0.20.30.60.3
Vertical activity count, locomotor time 10.61.43.2-1.0-0.9-1.1-0.10.5-0.21.8-1.71.7-1.60.2-1.21.3
Time >=10cm from walls, locomotor time 20.40.61.51.20.70.91.1-0.80.7-0.30.3-0.80.70.50.9-0.5
Bouts of movement, locomotor time 20.30.41.0-0.8-1.0-0.9-0.51.0-0.90.4-0.30.1-0.1-0.60.30.4
Total resting periods, locomotor time 20.10.20.4-0.4-0.6-0.5-0.30.7-0.70.2-0.1-0.10.1-0.40.30.4
Rest time, locomotor task time 20.20.31.2-0.1-0.0-0.10.2-0.10.20.8-0.91.1-0.90.50.10.1
Distance moved, locomotor task time 20.50.61.50.80.30.40.6-0.1-0.2-1.01.1-1.21.2-0.70.30.9
Vertical activity count, locomotor time 20.30.41.81.10.50.51.3-0.40.3-0.30.3-0.40.30.1-0.60.5
Light reinforcement 10.41.12.3-1.5-1.4-1.4-1.21.4-1.40.8-0.70.1-0.1-0.90.70.0
Light reinforcement 20.91.32.5-1.5-1.6-1.5-1.21.5-1.41.0-0.90.7-0.6-0.71.10.3
Bone: marrow area1.53.26.62.62.52.32.0-2.11.7-1.71.6-1.91.70.9-0.5-0.2
Bone: maximum diameter4.27.816.94.04.13.53.2-3.22.7-2.42.4-2.92.51.50.60.1
Bone: maximum force0.71.33.61.51.91.21.5-1.31.1-0.90.8-0.70.80.7-0.8-0.2
Bone: maximum moment1.01.74.41.82.11.61.6-1.51.3-1.11.1-0.91.10.7-0.90.2
Mean time between licks in bursts0.41.02.30.20.20.2-0.30.1-0.4-1.51.5-1.41.3-1.40.11.5
Mean num. licks in bursts0.91.42.80.60.20.71.1-1.01.31.3-1.41.5-1.61.5-1.7-0.3
Cd content in liver2.02.36.0-1.2-0.4-0.60.20.20.32.4-2.52.4-2.40.6-1.7-0.6
Co content in liver1.21.43.5-1.1-1.3-0.8-0.40.6-0.21.9-1.81.7-1.70.5-0.7-1.2
Cu content in liver0.10.20.4-0.1-0.4-0.20.10.2-0.00.6-0.60.5-0.50.30.0-0.7
Fe content in liver1.01.22.31.20.81.10.6-0.90.5-1.31.4-1.41.5-0.30.91.5
K content in liver0.30.31.1-0.3-1.0-0.6-0.30.7-0.60.5-0.40.3-0.2-0.11.1-0.1
Mg content in liver0.20.22.0-0.0-0.5-0.3-0.10.4-0.50.1-0.0-0.10.1-0.31.40.3
Mn content in liver0.10.10.2-0.4-0.3-0.4-0.20.4-0.30.4-0.40.4-0.3-0.1-0.2-0.2
Na content in liver1.11.22.5-1.3-1.0-1.4-1.41.5-1.6-0.20.2-0.10.2-1.41.10.6
Rb content in liver1.31.53.1-1.0-1.4-1.1-1.41.3-1.5-0.70.7-0.80.8-1.61.81.3
Se content in liver1.01.12.4-1.2-1.4-1.5-1.21.5-1.50.3-0.30.4-0.4-0.90.90.9
Sr content in liver2.01.73.1-1.6-1.4-1.5-0.91.3-1.01.8-1.71.7-1.7-0.40.1-0.1
Zn content in liver0.60.71.7-0.7-1.1-0.7-0.40.6-0.31.2-1.11.3-1.20.20.1-0.7
Bone: minimum diameter2.74.99.83.03.12.92.6-2.62.2-1.81.8-2.21.70.9-1.21.3
Time in familiar zone, hab. session 11.11.13.2-1.1-0.7-0.8-0.20.6-0.21.8-1.81.5-1.60.1-0.3-0.2
Time in novel zone, hab. session 11.41.43.51.31.10.90.5-0.60.2-1.91.9-1.71.8-0.10.40.8
Total zone transitions, hab. session 11.21.73.61.61.61.61.6-1.61.6-0.30.20.20.41.3-1.90.9
Total locomotion distance, hab. session 10.20.32.20.40.50.30.1-0.20.1-0.70.7-0.30.60.0-0.21.5
Locomotion velocity, hab. session 10.20.32.60.30.30.3-0.0-0.10.0-0.70.7-0.20.6-0.0-0.41.6
Time in familiar zone, hab. session 22.72.96.61.72.01.80.9-1.51.0-2.22.2-2.52.6-0.30.00.6
Time in novel zone, hab. session 21.51.54.4-1.1-1.2-1.0-0.30.8-0.31.8-1.82.0-2.10.4-0.70.2
Total zone transitions, hab. session 21.82.24.31.61.92.01.7-2.01.9-0.50.5-0.20.50.9-2.11.5
Total locomotion distance, hab. session 21.01.32.51.41.51.61.2-1.51.4-0.70.6-0.40.60.7-1.11.4
Locomotion velocity, hab. session 20.60.81.41.01.11.20.9-1.21.1-0.50.4-0.10.30.7-0.81.0
Novel to familiar place preference ratio0.10.10.40.0-0.1-0.0-0.30.2-0.3-0.60.6-0.50.5-0.3-0.3-0.1
Novelty place preference0.10.10.40.20.10.1-0.10.0-0.2-0.60.6-0.70.5-0.2-0.0-0.1
Time in novel zone, NPP test0.40.51.40.60.60.50.1-0.30.0-1.11.1-1.21.0-0.3-0.20.3
Total zone transitions, NPP test1.62.34.12.01.92.01.5-1.91.7-1.31.3-0.81.30.9-1.50.5
Total locomotion distance, NPP test1.21.72.61.51.61.61.0-1.51.3-1.51.5-1.01.30.4-0.81.2
Locomotion velocity, NPP test0.50.71.31.01.11.10.7-1.11.0-0.80.8-0.20.60.5-0.40.6
Intraocular pressure2.84.17.22.32.72.61.7-2.21.7-2.32.2-2.22.2-0.0-1.41.4
Delta distance traveled before/after self-admin1.01.02.31.51.31.31.3-1.21.1-0.20.2-0.50.31.10.2-1.1
Delta ambulatory time before/after self-admin1.11.43.21.81.41.51.1-1.20.9-1.11.1-1.31.20.60.8-0.7
Parametrial fat weight7.517.734.15.75.85.64.5-4.94.0-4.03.9-4.34.11.4-1.21.3
Pavlov. Cond. lever latency0.40.41.00.91.00.90.6-0.80.6-0.70.7-0.80.30.3-0.30.3
Pavlov. Cond. magazine entry latency0.30.40.80.90.40.90.5-0.80.7-0.70.6-0.40.70.5-0.8-0.1
Pavlov. Cond. change in total contacts0.20.20.80.0-0.20.10.2-0.10.30.5-0.50.7-0.30.5-0.9-0.3
Pavlov. Cond. index score0.20.20.50.50.10.50.5-0.60.70.2-0.20.40.20.7-0.6-0.6
Pavlov. Cond. latency score0.10.20.40.30.00.40.4-0.40.50.3-0.30.40.10.6-0.4-0.5
Pavlov. Cond. lever contacts0.40.51.0-1.0-1.0-0.9-0.80.9-0.80.5-0.50.6-0.2-0.50.3-0.4
Pavlov. Cond. magazine entry number1.01.22.4-1.4-1.0-1.5-1.31.5-1.50.3-0.2-0.1-0.4-1.21.50.5
Pavlov. Cond. intertrial magazine entries0.20.31.80.30.60.50.4-0.40.3-0.30.3-0.30.3-0.2-0.71.3
Pavlov. Cond. lever-magazine prob. diff.0.10.20.50.40.00.40.3-0.50.50.1-0.10.30.30.6-0.4-0.7
Pavlov. Cond. response bias0.10.10.50.0-0.20.20.1-0.20.20.2-0.20.40.10.3-0.7-0.3
Pavlov. Cond. lever latency1.62.16.0-0.2-0.3-0.00.7-0.51.02.4-2.42.2-1.91.7-0.9-1.4
Pavlov. Cond. magazine entry latency1.51.83.31.81.31.61.1-1.20.9-1.81.8-1.61.60.10.20.3
Pavlov. Cond. change in total contacts1.93.07.80.70.80.7-0.3-0.1-0.4-2.82.8-2.52.3-1.70.72.7
Pavlov. Cond. index score1.82.47.11.21.11.00.2-0.5-0.0-2.72.7-2.32.1-1.10.51.4
Pavlov. Cond. latency score1.72.36.81.41.11.10.4-0.60.1-2.62.6-2.32.1-0.80.41.0
Pavlov. Cond. lever contacts1.11.54.40.30.40.2-0.40.2-0.6-2.12.1-1.81.5-1.40.41.5
Pavlov. Cond. magazine entry number1.41.74.4-1.6-1.2-1.4-0.81.1-0.72.1-2.11.7-1.60.10.2-0.5
Pavlov. Cond. intertrial magazine entries0.10.10.3-0.10.5-0.10.40.00.00.6-0.60.1-0.10.30.2-0.2
Pavlov. Cond. lever-magazine prob. diff.1.52.06.21.21.11.00.3-0.50.1-2.52.5-2.11.8-0.90.51.1
Pavlov. Cond. response bias1.62.16.40.80.80.7-0.1-0.2-0.3-2.52.5-2.21.9-1.30.41.7
LgA PC1 addiction-like behavior0.20.51.60.40.30.80.9-0.50.70.7-0.70.4-0.70.7-1.30.1
Time in closed arm before self-admin0.30.42.8-0.6-0.2-0.3-0.20.3-0.20.5-0.50.3-0.4-0.6-0.11.7
Time in closed arm after self-admin0.70.71.9-1.3-0.6-0.7-0.50.5-0.31.0-1.00.9-1.0-0.3-1.40.7
Time in open arm before self-admin1.01.14.4-0.9-1.4-1.4-1.21.2-1.10.2-0.20.4-0.20.01.1-2.1
Time in open arm after self-admin1.01.15.20.80.00.1-0.20.2-0.5-1.21.2-1.41.3-0.32.3-1.0
Bone: periosteal estimation3.77.716.54.04.13.63.4-3.42.9-2.22.1-2.52.11.6-0.90.6
Bone: periosteal perimeter5.08.619.94.24.53.73.7-3.63.1-2.22.1-2.42.11.9-0.7-0.1
Bone: post-yield work0.81.22.6-0.30.3-0.3-0.90.5-0.8-1.61.6-1.51.6-1.31.0-1.2
Progressive ratio test 1 active lever presses1.21.53.21.01.21.00.6-0.70.3-1.61.6-1.81.6-0.8-0.21.8
Progressive ratio test 1 breakpoint1.21.43.50.91.10.90.5-0.70.2-1.61.6-1.81.6-0.9-0.21.9
Progressive ratio test 1 inactive lever presses1.52.25.91.20.91.20.1-0.5-0.0-2.42.4-2.32.3-1.10.90.9
Progressive ratio test 2 active lever presses2.12.54.12.01.72.01.3-1.41.0-1.91.9-1.91.9-0.2-0.61.3
Progressive ratio test 2 breakpoint2.32.64.52.11.72.11.4-1.51.1-1.91.9-1.91.8-0.0-0.61.3
Progressive ratio test 2 inactive lever presses1.22.03.91.61.41.70.9-0.90.5-1.91.9-2.02.0-0.50.51.0
ShA PR total presses0.70.81.6-0.9-0.9-0.5-1.31.0-1.1-0.80.9-0.70.7-1.10.70.7
Incentive Sensitization - Responses1.21.63.31.81.31.71.0-1.20.9-1.81.7-1.51.50.2-0.4-0.1
Incentive Sensitization - Breakpoint1.11.53.11.81.21.60.9-1.10.8-1.71.6-1.41.50.3-0.3-0.2
LgA PR total presses0.30.30.6-0.6-0.8-0.6-0.50.7-0.50.7-0.70.4-0.4-0.10.7-0.7
Sum of active levers in priming session hrs 5-60.70.72.5-0.6-1.0-0.8-1.00.9-1.0-0.40.4-0.40.4-0.41.6-0.8
Progressive ratio0.50.71.9-1.2-0.8-1.2-1.41.1-1.2-0.30.30.00.2-1.00.50.4
Food seeking constrained by brief footshock1.31.63.7-0.4-0.4-0.4-1.20.9-1.3-1.91.9-1.51.8-1.80.40.9
Seeking ratio, punishment vs. effort0.30.41.01.00.70.90.8-0.70.6-0.60.6-0.70.70.2-0.30.0
Retroperitoneal fat weight8.034.168.28.38.08.16.8-7.16.0-4.94.7-5.35.12.8-1.70.9
Reaction time number correct0.91.73.71.91.51.61.1-1.41.1-1.61.5-1.51.50.6-0.10.0
Reaction time mean minus median0.10.31.00.70.70.50.5-0.40.4-0.30.3-0.30.20.40.2-1.0
Reaction time mean minus median AUC0.20.61.60.80.90.71.0-0.80.90.3-0.40.3-0.41.0-0.5-1.3
Reaction time num false alarms0.10.10.30.2-0.00.2-0.1-0.0-0.1-0.50.5-0.50.5-0.2-0.2-0.3
Reaction time num false alarms AUC0.00.00.20.2-0.10.20.0-0.00.0-0.20.2-0.20.20.0-0.5-0.3
Reaction time trials correct on left0.91.73.71.91.51.61.1-1.41.1-1.61.5-1.51.50.6-0.10.0
Reaction time trials on left1.01.83.92.01.61.71.2-1.41.1-1.61.6-1.51.50.6-0.20.1
Reaction time mean0.40.71.7-0.10.0-0.10.4-0.00.31.1-1.11.3-1.30.9-0.4-1.3
Reaction time mean AUC0.40.61.7-0.5-0.4-0.6-0.00.4-0.11.2-1.11.2-1.30.5-0.2-1.1
Median of all reaction times0.81.13.0-0.3-0.2-0.40.30.10.31.5-1.51.7-1.71.0-0.5-1.4
Reaction time omissions0.10.20.60.20.70.40.3-0.20.1-0.50.5-0.50.2-0.3-0.40.5
Reaction time false alarm rate0.20.30.8-0.9-0.8-0.7-0.70.7-0.70.4-0.30.3-0.3-0.6-0.10.1
Reaction time premature initiation rate1.11.53.90.90.40.81.3-1.11.41.3-1.31.3-1.02.0-0.5-1.4
Reaction time premature initiations1.42.56.12.11.41.82.0-2.02.10.4-0.50.6-0.22.5-0.9-1.6
Std. dev. reaction times0.40.71.61.21.31.11.2-1.01.0-0.20.1-0.10.00.9-0.5-0.8
Reaction time trials completed1.01.83.92.01.61.71.2-1.41.1-1.61.6-1.51.50.6-0.20.1
Reaction time trials AUC1.01.94.12.01.61.71.2-1.51.1-1.71.6-1.61.60.6-0.30.2
Run reversals in cocaine runway, females1.01.02.01.21.11.01.4-1.21.30.5-0.50.8-0.81.3-0.2-0.6
Run reversals in cocaine runway, males0.90.91.8-1.3-1.0-1.2-1.21.3-1.30.3-0.2-0.10.0-1.01.0-0.1
Latency to leave start box in cocaine runway0.60.71.4-1.1-1.2-1.1-0.91.0-0.90.7-0.70.4-0.7-0.41.0-0.0
Latency to leave start box in cocaine runway, F0.91.02.0-1.4-1.3-1.3-0.91.1-0.91.2-1.20.8-1.1-0.20.20.1
Latency to leave start box in cocaine runway, M0.10.10.40.30.20.30.1-0.10.0-0.50.5-0.50.5-0.20.6-0.0
Std. dev. time between licks in bursts1.41.93.9-0.1-0.1-0.3-0.90.7-1.1-1.92.0-1.91.9-1.81.51.3
Total sessions with >9 infusions1.61.93.51.81.91.91.6-1.61.3-1.21.2-1.01.20.3-0.71.3
Short access day 1 total inactive lever presses1.11.43.01.71.11.41.0-1.00.7-1.21.1-1.51.50.41.3-0.3
Short access day 10 total inactive lever presses0.30.71.21.11.01.10.8-1.00.9-0.60.5-0.40.40.5-0.4-1.1
Short access day 1 total infusions0.30.40.91.00.80.90.7-0.70.5-0.60.6-0.80.60.30.40.4
Short access day 10 total infusions0.40.61.4-0.1-0.0-0.2-0.60.3-0.5-1.11.1-0.80.8-1.00.31.2
Short access total infusions0.50.71.60.80.80.60.3-0.50.2-1.31.3-1.01.1-0.40.30.9
ShA early post infusion interval0.50.51.3-0.6-0.8-0.5-0.90.8-0.9-0.30.3-0.40.4-0.71.10.4
ShA late post infusion interval0.10.10.70.40.40.40.3-0.30.3-0.0-0.0-0.20.00.60.2-0.9
ShA early loading1.11.22.7-0.4-0.5-0.0-0.90.3-0.6-1.61.7-1.41.5-1.10.61.4
ShA late loading0.50.71.6-1.1-1.0-1.0-1.31.1-1.1-0.10.1-0.00.0-0.80.80.1
Short access day 1 locomotion0.40.51.30.90.80.90.5-0.40.2-0.90.9-1.21.0-0.10.70.2
Short access day 10 total locomotion1.12.14.20.81.10.91.7-1.31.61.7-1.71.4-1.52.0-1.3-1.0
Short access total locomotion0.70.91.80.81.11.01.3-1.11.20.6-0.60.6-0.41.1-1.30.1
ShA early average infusions2.12.54.8-0.9-1.4-0.5-1.91.3-1.7-1.81.9-1.81.8-1.62.20.7
ShA late average infusions0.91.02.2-1.2-1.3-0.8-1.51.2-1.3-0.60.6-0.30.4-1.30.51.1
ShA early timeout1.81.84.0-0.6-0.9-0.3-1.60.9-1.3-2.02.0-1.61.9-1.21.20.5
ShA late timeout0.20.30.7-0.6-0.8-0.4-0.80.6-0.6-0.00.00.2-0.1-0.40.80.2
ShA early titration1.21.33.1-0.2-0.40.2-1.10.6-0.9-1.61.6-1.71.5-0.81.8-0.1
ShA late titration0.10.10.3-0.4-0.30.0-0.50.4-0.4-0.40.40.00.1-0.40.00.5
ShA total infusions0.60.71.5-0.8-0.9-0.3-1.20.9-1.0-0.90.9-0.60.7-0.90.80.7
One hour access (0.3 mA shock)3.54.010.61.61.21.00.0-0.4-0.3-3.33.3-3.23.2-1.11.80.3
Shock compulsivity1.22.36.61.91.52.11.9-1.91.9-0.30.3-0.00.11.4-2.60.2
Compulsive drug intake1.21.45.90.70.20.2-0.40.2-0.6-1.61.6-1.51.9-0.52.4-0.7
One hour access (shock baseline)0.30.50.90.80.90.70.7-0.70.5-0.60.6-0.80.7-0.0-0.50.9
Social response proportion2.83.16.72.01.71.82.3-2.02.30.5-0.61.1-0.92.2-2.6-1.4
Social responses3.14.08.42.92.42.82.3-2.42.0-1.71.7-1.82.00.9-1.3-0.0
Social time1.11.53.21.61.01.71.8-1.61.60.3-0.40.1-0.21.6-0.8-1.0
Soleus weight3.39.819.34.33.53.94.3-4.34.40.1-0.30.20.44.2-2.0-2.1
Bone: stiffness0.10.10.80.30.9-0.10.5-0.10.1-0.20.2-0.20.10.0-0.60.0
Tibialis anterior weight0.20.62.20.1-0.40.1-0.70.2-0.5-1.31.3-0.91.5-0.8-0.10.6
Time to tail flick, vehicle, before self-admin0.40.41.01.00.70.70.8-0.70.7-0.10.00.10.20.90.3-1.0
Time to tail flick, vehicle, after self-admin0.40.54.10.1-0.6-0.6-0.40.5-0.5-0.40.40.10.2-0.22.0-1.0
Time to tail flick, test, before self-admin1.21.23.20.20.20.20.8-0.50.81.4-1.41.4-1.41.3-1.8-0.9
Time to tail flick, test, after self-admin0.50.61.20.90.80.60.4-0.40.2-1.11.1-1.01.0-0.21.0-0.1
Delta time to tail flick, vehicle, before/after SA0.80.72.1-0.2-0.4-0.4-0.70.6-0.8-1.01.0-0.90.9-1.11.41.0
Delta time to tail flick, test, before/after SA0.40.51.40.40.40.2-0.0-0.1-0.1-1.01.0-0.91.0-0.61.20.2
Tibia length1.13.17.42.12.32.02.7-2.22.40.7-0.80.6-0.52.3-0.9-0.4
Ambulatory time before self-admin1.92.96.6-0.20.20.21.2-0.61.12.5-2.62.4-2.51.7-2.5-0.5
Ambulatory time after self-admin2.52.96.61.10.80.81.9-1.21.62.1-2.11.7-2.02.6-0.8-2.3
Bone: tissue strength0.40.41.9-0.7-0.5-0.4-0.70.6-0.7-0.20.2-0.10.5-1.10.11.4
Total heroin consumption2.22.54.41.92.02.11.5-1.61.2-1.81.7-1.71.7-0.1-0.61.6
Total infusions0.30.41.10.40.30.80.4-0.40.2-0.80.8-0.90.8-0.5-0.61.1
Bone: trabecular number0.61.02.21.30.70.90.6-0.50.2-1.51.5-1.41.4-0.20.01.1
Bone: trabecular spacing0.20.20.5-0.7-0.6-0.5-0.70.6-0.60.1-0.1-0.0-0.2-0.60.10.2
Bone: trabecular thickness3.94.811.33.42.82.82.5-2.62.2-1.91.8-2.21.91.60.5-0.3
Bone: trabecular tissue density0.40.61.7-0.80.0-0.8-0.10.4-0.11.2-1.20.9-1.30.50.2-1.2
Water consumed over 24 hours0.60.81.61.21.00.71.3-1.01.10.3-0.30.6-0.41.1-1.20.3
Number of responses in last shaping day0.30.42.30.00.20.4-0.0-0.20.1-0.60.6-0.40.3-0.5-1.01.5