Hub : Genes

LOC102548590

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose mRNA stability LOC102548590 0.03 0.02 3.8e-04 0.04 0.03 0.03 0.03 6.9e-05 3.0e-04 5.0e-04 2.8e-04
2 Liver gene expression LOC102548590 0.47 0.1 0.0e+00 0.36 0.25 0.36 0.32 4.1e-42 5.5e-28 1.7e-41 2.1e-36
3 pVTA gene expression LOC102548590 0.13 0.07 8.9e-05 0.07 0.09 0.06 0.08 4.2e-04 1.3e-04 1.4e-03 2.2e-04
4 RMTg gene expression LOC102548590 0.23 0.11 1.4e-04 0.09 0.11 0.12 0.13 1.9e-03 6.2e-04 3.2e-04 2.4e-04
5 Liver intron excision ratio chr7_82242153_82246389 0.06 0.03 2.3e-06 0.01 0.03 0.03 0.02 9.0e-03 1.2e-04 4.5e-04 8.7e-04
6 Adipose gene expression LOC102548590 0.13 0.07 5.9e-11 0.11 0.07 0.1 0.1 5.6e-12 3.3e-08 1.2e-10 4.0e-11
7 PL gene expression LOC102548590 0.1 0.05 4.7e-09 0.1 0.09 0.07 0.1 3.4e-11 8.2e-10 3.3e-08 4.7e-11
8 BLA gene expression LOC102548590 0.14 0.07 2.6e-06 0.05 0.1 0.1 0.1 1.6e-03 3.3e-06 6.9e-06 5.7e-06
9 NAcc gene expression LOC102548590 0.06 0.03 2.1e-06 0.04 0.05 0.04 0.04 3.2e-05 2.0e-06 2.8e-05 1.4e-05
10 Liver intron excision ratio chr7_82238023_82246382 0.04 0.02 1.6e-03 0.02 0.01 0.01 0.01 1.9e-03 1.0e-02 2.9e-02 1.3e-02
11 Brain gene expression LOC102548590 0.1 0.05 2.2e-08 0.07 0.08 0.08 0.07 8.3e-07 1.4e-07 3.6e-08 4.1e-07
12 OFC gene expression LOC102548590 0.27 0.11 4.2e-04 0.03 0.11 0.1 0.08 6.7e-02 1.2e-03 2.6e-03 5.9e-03

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12
Bone: apparent density0.40.61.7-0.41.10.41.10.9-0.4-0.6-0.5-0.0-1.30.6-1.0
Area under the delay curve1.81.94.1-1.4-0.8-1.4-1.5-1.51.11.6-0.9-2.01.61.3-1.1
BMI with tail5.818.831.14.95.65.24.93.6-5.0-5.14.82.4-2.4-3.62.6
BMI without tail4.18.519.43.44.43.83.62.9-2.9-3.42.70.9-1.8-1.70.4
Body weight5.020.939.05.06.25.65.44.4-5.1-5.14.42.7-3.3-3.81.7
Weight adjusted by age0.50.61.60.70.90.60.2-0.4-0.6-0.71.30.00.3-1.30.7
Bone surface0.40.61.70.21.10.61.11.0-0.9-0.8-0.30.5-1.30.1-0.8
Bone volume0.20.41.4-0.70.3-0.10.70.5-0.0-0.2-0.80.1-1.20.6-1.0
Breakpoint value in progressive ratio session1.01.13.31.00.70.91.51.6-0.8-0.8-0.00.9-1.8-0.1-0.0
Number of licking bursts0.91.02.4-0.3-1.5-0.9-1.5-1.11.01.2-0.3-0.41.50.40.1
Context. condit. distance diff. score0.30.41.21.10.90.70.30.2-0.8-0.20.8-0.10.5-0.60.2
Locomotion velocity, session 10.30.41.4-0.2-0.7-0.4-0.8-0.90.20.50.2-0.01.2-0.60.5
Locomotion distance, session 11.51.94.7-0.3-2.0-1.3-2.0-2.11.31.3-0.0-1.02.2-0.00.4
Locomotion velocity, session 23.94.56.5-2.3-2.3-2.5-2.1-2.02.52.5-2.2-1.61.71.9-1.6
Locomotion distance, session 22.43.47.6-0.8-2.5-2.0-2.6-2.52.01.7-0.7-1.02.80.40.2
Locomotion velocity, session 31.11.23.81.90.51.00.50.5-1.3-0.51.21.30.2-1.51.3
Locomotion distance, session 30.91.05.82.40.50.70.10.9-1.0-0.30.31.40.5-1.00.7
Stereotopy head waving bouts, day 30.20.20.4-0.3-0.3-0.2-0.6-0.60.40.40.4-0.60.40.10.2
Stereotopy head waving duration, day 31.72.05.2-1.6-1.4-1.4-1.7-2.31.61.5-0.1-1.91.20.4-0.3
Locomotion velocity, session 70.10.10.30.10.20.2-0.1-0.1-0.5-0.10.30.1-0.3-0.30.1
Locomotion distance, session 70.40.51.31.00.20.5-0.00.2-0.8-0.50.71.2-0.1-0.81.0
Stereotopy head waving bouts, day 74.55.18.3-2.4-2.4-2.4-2.6-2.92.42.1-1.1-2.72.51.6-1.1
Stereotopy head waving duration, day 72.73.35.5-1.9-2.1-2.0-2.1-2.31.91.8-1.0-2.02.11.1-0.8
Locomotion velocity, session 80.40.51.50.2-0.8-0.5-0.8-1.10.40.70.2-0.21.2-0.80.5
Locomotion distance, session 80.81.14.50.8-1.2-0.8-1.6-1.40.71.10.1-0.52.1-0.30.5
Degree of sensitization distance0.40.41.1-0.70.40.50.5-0.0-0.3-0.90.90.3-1.0-0.10.8
Degree of sensitization stereotypy4.75.16.5-2.5-2.5-2.6-2.3-2.52.32.3-1.9-2.52.11.9-1.7
Conditioned locomotion0.30.31.00.70.10.30.4-0.1-0.6-0.70.70.60.4-0.51.0
Cocaine response after cond. corrected0.20.21.2-1.1-0.1-0.10.20.00.5-0.10.0-0.4-0.50.50.0
Cocaine response after cond. not corrected0.30.31.6-1.3-0.5-0.3-0.1-0.30.90.1-0.0-0.7-0.10.70.0
Cocaine response before conditioning0.20.20.80.2-0.5-0.3-0.7-0.60.30.40.1-0.30.90.10.0
Saline control response0.81.02.70.80.50.91.01.4-0.9-0.80.31.6-1.6-0.10.9
Bone: connectivity density0.81.33.70.21.60.91.71.7-1.0-1.0-0.30.8-1.90.2-0.7
Bone: cortical apparent density2.93.86.2-1.5-2.3-2.2-2.3-1.82.52.0-1.9-1.71.61.9-1.3
Bone: cortical area0.30.51.21.10.20.4-0.3-0.6-0.3-0.61.1-0.41.0-0.80.5
Bone: cortical porosity0.60.62.3-0.41.50.81.00.6-0.6-0.80.4-0.8-0.60.5-0.7
Bone: cortical porosity0.80.92.70.11.61.21.30.8-1.0-1.21.0-0.3-0.80.1-0.1
Bone: cortical thickness0.30.51.70.2-0.3-0.3-0.8-1.00.50.10.3-1.31.10.5-0.2
Bone: cortical thickness0.20.20.50.40.70.40.5-0.1-0.7-0.60.7-0.2-0.2-0.30.3
Bone: cortical tissue density2.93.86.2-1.5-2.3-2.2-2.3-1.82.52.0-1.9-1.71.61.9-1.3
Condit. Reinf. active minus inactive responses0.60.71.71.10.70.90.30.6-0.6-0.90.91.30.1-0.51.3
Condit. Reinf. active-inactive response ratio0.10.10.5-0.20.1-0.2-0.30.10.30.1-0.6-0.10.30.7-0.3
Condit. Reinf. active responses1.51.94.42.00.91.20.20.5-1.4-1.11.61.90.8-1.42.1
Condit. Reinf. inactive responses2.42.86.52.30.51.20.10.1-1.8-1.02.12.11.1-2.42.6
Incentive salience index mean0.60.72.21.50.80.90.30.8-0.7-0.70.71.20.1-0.50.9
Condit. Reinf. lever presses0.10.21.31.10.10.2-0.30.40.10.2-0.10.60.6-0.30.1
Condit. Reinf. active minus inactive responses2.02.54.21.91.31.61.30.7-2.0-1.42.01.6-0.6-2.01.7
Condit. Reinf. active-inactive response ratio4.04.26.02.02.12.32.11.3-2.3-2.32.41.9-1.4-2.21.8
Condit. Reinf. active responses0.81.13.71.90.50.90.1-0.1-1.2-0.31.40.90.6-1.71.1
Condit. Reinf. inactive responses1.21.53.20.2-1.4-1.2-1.7-1.11.01.8-1.0-0.81.70.4-0.9
Condit. Reinf. lever presses0.30.51.5-0.2-0.3-0.7-0.6-0.9-0.21.2-0.4-0.61.20.1-0.4
Condit. Reinf. lever reinforcers received0.50.83.01.70.30.5-0.2-0.4-0.90.21.00.51.0-1.40.7
Conditioned reinforcement - actives0.40.40.90.50.80.70.90.9-0.5-0.60.10.5-0.50.3-0.1
Conditioned reinforcement - inactives0.50.61.61.21.30.90.50.4-0.9-0.70.70.20.8-0.40.1
Conditioned locomotion2.12.54.91.72.21.91.92.2-1.6-1.80.91.4-1.2-0.90.2
Patch foraging indifference point 0 sec1.11.83.21.61.81.61.41.3-1.4-1.61.21.0-0.8-1.10.9
Patch foraging indifference point AUC0.60.72.61.1-0.60.7-0.00.4-0.6-0.61.11.10.1-0.81.6
Delay disc. indifference point, 0s delay0.10.11.10.21.00.10.2-0.2-0.60.10.1-0.30.1-0.1-0.2
Delay disc. indifference point, 16s delay2.82.84.5-1.7-1.3-1.6-2.0-2.01.71.7-1.0-2.11.91.3-1.2
Delay disc. indifference point, 2s delay1.51.72.9-1.2-0.8-1.5-1.5-1.41.11.6-1.1-1.71.21.2-1.0
Delay disc. indifference point, 24s delay2.12.14.1-1.4-1.7-1.5-2.0-2.01.21.4-0.4-1.42.00.3-0.0
Delay disc. indifference point, 4s delay0.60.71.6-0.7-0.1-0.8-0.9-1.10.50.9-0.4-1.31.20.6-0.6
Delay disc. indifference point, 8s delay0.30.31.2-0.50.3-0.2-0.3-0.1-0.00.5-0.2-1.10.91.0-0.5
Indifference point function ln k0.20.31.5-0.60.7-0.30.3-0.50.40.2-0.2-1.20.10.5-0.9
Indifference point function log k0.20.31.5-0.60.7-0.30.3-0.50.40.2-0.2-1.20.10.5-0.9
Patch foraging total patch changes 0 sec0.91.42.21.41.51.31.10.8-1.3-1.41.30.8-0.6-1.21.0
Patch foraging total patch changes 12 sec0.50.61.90.9-0.10.80.51.4-0.5-0.70.21.3-0.8-0.30.8
Patch foraging total patch changes 18 sec1.21.52.31.51.11.51.11.0-1.2-1.51.41.1-0.6-1.31.1
Patch foraging total patch changes 24 sec0.20.20.8-0.3-0.9-0.4-0.6-0.10.60.7-0.40.3-0.10.00.2
Patch foraging total patch changes 6 sec0.71.02.51.50.10.80.30.8-1.0-0.90.91.6-0.1-1.21.6
Patch foraging time to switch 0 sec1.01.54.1-1.5-0.9-1.3-0.8-0.11.31.2-2.0-0.5-0.21.4-1.7
Patch foraging water rate 0 sec0.91.54.51.20.61.10.9-0.3-1.0-1.42.10.30.3-1.71.8
Patch foraging water rate 12 sec0.10.20.60.20.50.40.80.0-0.2-0.50.6-0.2-0.6-0.50.3
Patch foraging water rate 18 sec2.33.15.41.71.21.81.50.8-1.7-2.22.22.0-0.9-2.32.2
Patch foraging water rate 24 sec0.60.82.30.30.10.80.70.2-0.6-1.31.31.0-0.5-0.91.5
Patch foraging water rate 6 sec0.81.14.00.80.81.00.7-0.5-1.0-1.22.00.10.3-1.41.4
Seeking ratio, delayed vs. immediate footshock0.30.31.00.81.00.30.80.5-0.6-0.3-0.10.4-0.4-0.0-0.3
Distance traveled before self-admin0.10.10.30.50.10.5-0.10.2-0.1-0.50.60.00.5-0.30.4
Distance traveled after self-admin0.50.51.6-0.8-0.0-0.4-0.10.01.00.8-0.8-1.00.10.7-1.3
Extensor digitorum longus weight1.76.614.32.72.32.71.60.6-3.0-3.33.81.8-0.1-3.52.5
Bone: elastic displacement2.62.96.3-2.2-1.5-1.8-1.9-2.51.71.5-0.7-2.01.91.2-0.8
Bone: elastic work1.01.34.2-1.2-0.6-0.9-1.1-1.90.80.70.0-2.11.50.9-0.7
Bone: endosteal estimation0.81.84.32.00.81.21.11.3-1.4-1.00.72.0-0.9-2.10.5
Bone: endosteal perimeter0.40.82.61.60.50.90.30.3-0.9-0.80.90.70.7-1.60.4
Epididymis fat weight2.04.88.82.52.72.42.53.0-2.3-2.01.02.4-2.2-1.20.9
Delta time in closed arm before/after self-admin1.71.62.9-0.9-0.7-1.4-1.3-1.31.51.4-1.3-1.61.00.8-1.7
Delta time in open arm before/after self-admin0.80.81.70.61.31.01.10.8-1.0-1.20.70.7-0.5-0.70.2
Diff in mean of infusions in LGA sessions0.50.61.20.30.60.50.90.4-1.1-1.00.51.0-0.6-0.90.6
Delay discount exponential model param2.22.44.31.61.01.61.71.6-1.3-1.81.22.1-1.7-1.51.2
Extinction: sum of active levers before priming0.20.20.6-0.3-0.6-0.3-0.00.30.60.4-0.80.0-0.40.6-0.6
Active lever presses in extinction session 60.20.20.5-0.4-0.4-0.5-0.3-0.10.40.7-0.7-0.40.50.5-0.6
Bone: final force0.71.12.01.41.41.41.20.9-1.1-1.31.3-0.1-0.7-0.60.2
Bone: final moment0.30.50.90.90.90.90.70.4-0.6-0.80.9-0.5-0.4-0.3-0.2
Food consumed during 24 hour testing period0.60.72.21.0-0.00.70.60.9-0.7-0.70.41.5-0.9-0.80.9
Glucose1.21.73.70.01.51.21.61.5-1.9-1.50.71.5-1.5-0.61.0
Heart weight0.60.91.6-1.3-0.7-0.8-0.6-0.91.20.6-0.7-1.30.81.2-0.8
Delay discount hyperbolic model param2.12.34.41.61.01.51.61.5-1.2-1.71.12.1-1.6-1.41.2
Intermittent access intake day 1-15 change0.60.61.1-0.7-0.9-0.6-0.8-0.90.80.6-0.1-1.01.00.5-0.2
Intermittent access intake escalation0.30.30.8-0.4-0.6-0.4-0.5-0.70.50.5-0.0-0.90.70.5-0.1
Intermittent access intake escalation 20.70.72.0-0.6-0.9-0.7-0.9-1.40.60.60.2-1.41.3-0.0-0.2
Intermitt. access day 1 inactive lever presses0.10.10.30.20.60.30.50.2-0.4-0.10.10.2-0.2-0.4-0.1
Intermitt. access day 15 inactive lever presses2.73.04.41.61.81.91.81.1-2.0-2.12.11.5-0.9-1.51.8
Intermitt. access escalation Index1.41.33.51.00.30.90.70.6-0.9-0.91.31.7-0.4-1.51.9
Intermittent access day 1 total infusions0.50.61.90.40.90.50.91.4-0.3-0.4-0.50.7-1.20.7-0.4
Intermittent access day 15 total infusions0.20.20.40.20.50.30.60.6-0.0-0.2-0.1-0.1-0.60.6-0.3
Intermittent access terminal intake (last 3 days)0.10.10.20.40.30.40.30.3-0.2-0.40.40.00.00.20.2
Intermittent access total infusions0.20.20.60.20.60.30.50.60.1-0.1-0.3-0.2-0.40.8-0.7
Intermittent access day 1 locomotion0.60.61.30.81.10.81.01.1-0.7-0.70.20.6-1.1-0.00.0
Intermittent access day 15 total locomotion0.80.91.81.31.31.10.80.9-1.2-1.00.80.7-0.0-0.70.4
Intermittent access total locomotion0.50.61.31.01.11.00.50.5-0.9-0.91.00.20.2-0.40.5
Intermittent access standard deviation0.20.20.70.40.30.2-0.2-0.6-0.3-0.20.6-0.80.5-0.3-0.2
Left kidney weight0.41.14.30.80.60.81.51.5-0.6-0.4-0.30.6-2.1-0.7-0.9
Right kidney weight1.02.97.21.31.91.92.62.2-1.4-1.50.71.0-2.7-1.2-0.5
Cocaine induced anxiety0.40.51.0-1.0-0.9-0.7-0.3-0.40.70.8-0.8-0.6-0.51.0-0.7
Post-drug Anxiety1.21.33.0-1.6-0.9-1.1-0.3-0.41.21.2-1.4-1.0-0.61.7-1.3
Baseline Anxiety0.20.20.50.60.40.30.2-0.0-0.4-0.50.50.40.7-0.60.5
Tail length0.30.95.0-0.00.90.20.30.50.70.4-0.9-1.1-0.70.9-2.2
Length with tail0.51.84.11.22.01.61.61.5-1.4-1.20.80.9-1.3-1.2-0.3
Length without tail2.04.38.91.91.41.91.40.8-2.6-2.12.62.3-0.5-3.02.7
Times rat made contact with spout0.30.41.10.7-0.5-0.1-0.31.00.10.3-1.01.0-0.10.4-0.3
Lifetime Intake0.40.41.20.60.80.70.81.1-0.3-0.60.00.3-0.80.6-0.2
Liver weight, left1.32.14.31.92.11.71.51.3-1.3-1.61.01.0-1.2-1.4-0.1
Liver weight, right3.25.311.82.82.42.81.40.9-2.2-2.83.41.50.2-2.72.2
Locomotor activity1.82.95.31.82.32.32.31.9-1.6-1.71.70.8-1.4-0.90.6
Locomotor testing distance0.40.71.50.61.11.21.20.7-0.8-0.71.10.0-0.8-0.40.5
Locomotor testing rearing1.21.84.01.21.81.71.92.0-1.2-1.10.81.0-1.5-0.20.4
Locomotion in novel chamber0.30.40.90.70.50.81.00.8-0.8-0.70.50.5-0.6-0.30.2
Locomotion in novel chamber post-restriction0.40.51.9-0.6-0.2-0.30.10.80.60.6-1.2-0.3-0.41.4-0.9
Fecal boli incidents, locomotor time 10.80.92.4-0.8-0.5-1.0-1.2-1.60.90.7-0.2-1.21.30.6-0.2
Change in fecal boli incidents, locomotor task1.91.83.71.40.81.11.41.1-1.6-1.30.81.9-1.0-1.91.0
Time >=10cm from walls, locomotor time 11.71.73.71.31.51.51.10.5-1.5-1.61.91.0-0.6-1.11.5
Bouts of movement, locomotor time 10.30.31.2-0.20.90.10.60.1-0.2-0.1-0.2-0.9-0.30.6-1.1
Total resting periods, locomotor time 10.20.20.8-0.20.5-0.10.2-0.4-0.1-0.0-0.0-0.90.20.3-0.7
Rest time, locomotor task time 10.10.10.3-0.10.3-0.10.10.30.10.1-0.5-0.3-0.30.5-0.5
Distance moved, locomotor task time 10.60.61.1-0.7-0.8-0.8-0.7-1.01.00.9-0.5-1.00.60.6-0.7
Vertical activity count, locomotor time 10.20.20.5-0.5-0.6-0.4-0.7-0.60.50.5-0.1-0.30.60.60.2
Time >=10cm from walls, locomotor time 24.34.57.32.42.72.52.62.3-2.4-2.41.71.6-2.1-1.10.7
Bouts of movement, locomotor time 20.50.61.7-0.7-0.3-0.6-1.0-1.00.50.7-0.2-1.31.00.5-0.5
Total resting periods, locomotor time 20.70.71.6-0.7-0.6-0.8-1.3-1.20.70.9-0.3-1.21.10.5-0.5
Rest time, locomotor task time 21.41.63.3-1.2-1.8-1.8-1.5-1.41.61.4-1.3-0.50.70.7-0.3
Distance moved, locomotor task time 20.20.30.80.00.90.70.60.4-0.3-0.40.4-0.7-0.30.4-0.5
Vertical activity count, locomotor time 21.31.42.91.11.71.61.61.4-1.2-1.20.90.2-1.2-0.0-0.1
Light reinforcement 11.32.35.5-1.4-1.9-1.5-1.6-1.32.31.5-1.4-1.40.81.3-1.2
Light reinforcement 20.30.41.3-0.2-0.3-0.5-0.10.31.00.6-1.1-0.1-0.60.6-0.9
Bone: marrow area0.92.04.62.20.91.31.11.3-1.5-1.10.82.0-0.9-2.10.6
Bone: maximum diameter1.12.04.42.11.11.51.00.8-1.5-1.61.51.2-0.2-2.01.0
Bone: maximum force0.91.53.31.81.31.51.10.7-1.4-1.51.70.3-0.6-1.20.6
Bone: maximum moment0.40.71.71.30.91.00.70.2-0.8-1.11.3-0.2-0.2-0.90.2
Mean time between licks in bursts0.20.30.9-1.00.1-0.3-0.3-0.60.40.3-0.1-0.90.30.7-0.5
Mean num. licks in bursts0.40.41.50.20.70.30.81.1-0.4-0.6-0.60.4-1.20.1-0.6
Cd content in liver3.84.17.7-2.0-2.7-2.5-2.4-2.82.02.5-1.2-1.52.20.6-0.3
Co content in liver2.22.66.1-0.9-1.6-1.6-2.0-2.41.41.9-0.3-1.82.50.5-0.2
Cu content in liver0.50.61.70.11.30.61.01.3-0.2-0.4-0.50.4-1.30.3-0.8
Fe content in liver0.30.42.40.7-0.20.30.30.6-0.4-0.5-0.01.5-0.7-0.50.6
K content in liver5.04.98.83.02.02.62.22.6-2.4-2.31.82.4-1.9-1.71.5
Mg content in liver0.91.02.71.11.11.11.01.6-0.8-1.00.31.1-1.0-0.40.2
Mn content in liver0.70.81.51.20.81.11.01.2-0.7-0.90.60.9-1.1-0.30.3
Na content in liver5.05.212.82.42.62.42.63.6-2.4-1.90.52.8-2.5-1.00.3
Rb content in liver0.50.63.00.10.80.61.01.3-0.0-0.4-0.40.8-1.70.2-0.4
Se content in liver0.20.31.00.40.90.50.30.7-1.0-0.3-0.10.5-0.2-0.1-0.2
Sr content in liver0.50.51.71.10.70.40.80.8-0.10.3-0.4-0.2-0.90.0-1.3
Zn content in liver0.30.40.91.00.20.4-0.10.3-0.6-0.40.40.90.6-0.90.7
Bone: minimum diameter1.22.36.12.51.11.70.70.6-1.6-1.92.00.90.3-2.01.1
Time in familiar zone, hab. session 10.50.51.0-0.2-1.0-1.0-0.9-1.00.61.0-0.5-0.30.80.0-0.1
Time in novel zone, hab. session 10.60.61.9-0.51.00.91.00.9-0.4-0.90.4-0.0-1.40.3-0.1
Total zone transitions, hab. session 12.12.99.8-0.5-1.7-1.4-2.3-3.10.91.30.7-1.72.9-0.40.7
Total locomotion distance, hab. session 11.11.54.80.9-0.10.3-0.7-1.7-0.6-0.42.2-0.41.7-1.32.0
Locomotion velocity, hab. session 11.01.44.70.8-0.5-0.1-1.1-1.8-0.10.11.6-0.62.2-1.01.6
Time in familiar zone, hab. session 21.31.33.1-0.9-1.8-1.6-1.4-1.21.21.3-1.3-0.51.00.4-0.5
Time in novel zone, hab. session 21.31.33.10.71.71.51.00.6-1.2-1.41.80.2-0.3-0.60.8
Total zone transitions, hab. session 21.82.35.70.1-2.4-1.5-2.2-2.01.41.7-0.3-0.52.3-0.30.5
Total locomotion distance, hab. session 20.70.92.30.6-1.3-0.4-1.2-1.20.60.30.70.11.5-0.81.3
Locomotion velocity, hab. session 20.60.82.10.4-1.4-0.6-1.2-1.10.90.50.30.01.4-0.61.0
Novel to familiar place preference ratio0.60.61.40.40.90.80.30.4-1.1-1.21.00.60.1-0.50.9
Novelty place preference0.40.41.20.10.90.70.40.4-0.9-1.10.80.4-0.2-0.30.6
Time in novel zone, NPP test0.50.51.20.01.00.80.40.3-1.0-1.11.00.4-0.1-0.40.7
Total zone transitions, NPP test1.11.65.20.8-1.4-0.6-1.7-1.80.71.10.9-0.42.3-0.91.4
Total locomotion distance, NPP test0.91.33.91.4-0.30.5-0.6-0.9-0.3-0.31.80.61.3-1.62.0
Locomotion velocity, NPP test0.91.33.91.5-0.50.4-0.6-0.8-0.1-0.31.70.51.4-1.52.0
Intraocular pressure0.20.31.50.10.10.0-0.5-0.5-0.50.10.4-0.21.2-1.00.3
Delta distance traveled before/after self-admin0.20.30.9-0.70.3-0.20.30.10.40.5-0.5-0.5-0.50.4-0.9
Delta ambulatory time before/after self-admin0.20.30.7-0.8-0.1-0.40.0-0.00.50.7-0.6-0.3-0.40.5-0.7
Parametrial fat weight3.36.59.62.83.03.13.02.9-2.8-2.52.02.3-2.2-2.11.0
Pavlov. Cond. lever latency0.10.10.4-0.60.40.20.3-0.1-0.5-0.50.4-0.2-0.4-0.30.0
Pavlov. Cond. magazine entry latency0.20.20.7-0.40.0-0.20.10.40.50.3-0.8-0.1-0.30.7-0.8
Pavlov. Cond. change in total contacts0.60.61.0-0.5-1.0-0.9-0.9-0.70.91.0-0.6-0.61.00.6-0.1
Pavlov. Cond. index score0.20.20.60.0-0.5-0.5-0.4-0.10.80.7-0.6-0.30.40.6-0.4
Pavlov. Cond. latency score0.30.30.80.1-0.8-0.6-0.6-0.30.90.8-0.6-0.30.60.6-0.2
Pavlov. Cond. lever contacts0.20.30.60.5-0.7-0.4-0.6-0.20.80.7-0.3-0.30.60.3-0.0
Pavlov. Cond. magazine entry number0.10.10.3-0.1-0.3-0.1-0.3-0.6-0.1-0.10.5-0.10.3-0.30.5
Pavlov. Cond. intertrial magazine entries1.62.03.41.71.41.40.90.7-1.8-1.31.81.4-0.2-1.51.7
Pavlov. Cond. lever-magazine prob. diff.0.10.10.20.4-0.1-0.1-0.00.30.40.4-0.50.0-0.00.5-0.3
Pavlov. Cond. response bias0.20.20.60.20.1-0.1-0.10.30.60.5-0.6-0.40.10.6-0.8
Pavlov. Cond. lever latency0.20.20.7-0.30.40.60.40.50.2-0.70.6-0.0-0.8-0.10.3
Pavlov. Cond. magazine entry latency0.50.51.30.40.80.31.11.0-0.6-0.4-0.60.6-1.10.5-0.7
Pavlov. Cond. change in total contacts0.10.10.50.30.60.10.5-0.4-0.70.00.2-0.30.1-0.3-0.4
Pavlov. Cond. index score0.10.10.30.40.2-0.00.50.3-0.60.1-0.50.4-0.20.1-0.4
Pavlov. Cond. latency score0.10.10.30.20.1-0.20.50.2-0.40.2-0.50.3-0.20.2-0.4
Pavlov. Cond. lever contacts0.50.61.7-0.2-1.0-1.1-0.8-0.80.31.3-1.0-0.31.00.5-0.5
Pavlov. Cond. magazine entry number1.11.43.1-1.2-1.4-1.1-1.8-1.21.51.1-0.5-1.11.40.5-0.2
Pavlov. Cond. intertrial magazine entries0.20.30.90.90.60.70.30.9-0.50.10.20.50.1-0.50.0
Pavlov. Cond. lever-magazine prob. diff.0.10.20.40.50.30.10.70.4-0.60.1-0.40.5-0.40.1-0.3
Pavlov. Cond. response bias0.10.20.60.4-0.3-0.5-0.3-0.4-0.20.8-0.5-0.10.70.3-0.2
Time in closed arm before self-admin0.70.81.70.70.61.11.11.3-0.8-0.70.71.0-1.3-0.60.6
Time in closed arm after self-admin0.70.71.2-0.7-0.9-1.0-0.9-0.61.11.1-1.0-0.60.20.3-0.8
Time in open arm before self-admin0.10.10.5-0.0-0.3-0.3-0.3-0.70.00.10.2-0.30.6-0.10.2
Time in open arm after self-admin0.70.81.30.80.70.80.80.2-1.1-1.21.20.90.1-1.11.1
Bone: periosteal estimation0.51.03.82.00.61.00.50.5-1.0-0.91.00.90.0-1.70.5
Bone: periosteal perimeter0.40.61.91.4-0.20.4-0.2-0.3-0.5-0.60.90.31.1-1.20.8
Bone: post-yield work1.92.57.82.80.81.51.01.1-1.5-1.11.41.9-0.4-2.41.5
Progressive ratio test 1 active lever presses2.83.04.41.72.11.81.91.6-1.8-1.91.41.9-1.6-1.51.3
Progressive ratio test 1 breakpoint2.93.05.31.62.31.81.91.7-1.8-1.91.41.9-1.6-1.41.1
Progressive ratio test 1 inactive lever presses0.50.50.90.71.00.70.70.8-0.7-0.70.60.9-0.8-0.30.7
Progressive ratio test 2 active lever presses1.31.42.11.41.21.41.41.3-1.2-1.31.01.0-1.0-0.90.7
Progressive ratio test 2 breakpoint0.60.61.00.90.90.91.01.0-0.8-0.80.60.7-0.7-0.70.3
Progressive ratio test 2 inactive lever presses0.20.20.50.60.60.70.50.5-0.4-0.70.60.20.3-0.30.4
Incentive Sensitization - Responses0.30.30.90.90.60.70.70.9-0.4-0.50.30.2-0.3-0.2-0.0
Incentive Sensitization - Breakpoint0.10.10.40.60.30.40.40.6-0.2-0.20.0-0.1-0.1-0.2-0.2
Sum of active levers in priming session hrs 5-60.10.10.20.30.30.20.1-0.30.1-0.30.4-0.40.4-0.0-0.2
Progressive ratio2.73.14.8-1.5-1.4-1.8-1.9-2.01.71.9-1.3-2.22.21.8-1.3
Food seeking constrained by brief footshock0.91.12.70.90.20.80.50.2-1.2-1.21.31.30.0-1.41.7
Seeking ratio, punishment vs. effort4.25.16.92.11.82.42.32.0-2.4-2.62.12.6-2.0-2.52.1
Retroperitoneal fat weight1.65.311.42.53.42.82.72.7-2.5-2.51.71.6-1.5-1.60.7
Reaction time number correct0.81.12.41.51.01.20.90.5-1.0-1.01.41.00.3-1.11.2
Reaction time mean minus median1.92.65.02.21.51.81.61.6-1.8-1.61.41.8-0.9-1.41.3
Reaction time mean minus median AUC0.20.30.80.90.60.60.60.8-0.5-0.50.10.6-0.5-0.2-0.0
Reaction time num false alarms0.20.30.70.2-0.7-0.5-0.4-0.30.50.8-0.5-0.80.10.5-0.7
Reaction time num false alarms AUC0.20.30.80.4-0.7-0.4-0.5-0.40.50.9-0.4-0.80.30.3-0.6
Reaction time trials correct on left0.81.12.41.51.01.20.90.5-1.0-1.01.41.00.3-1.11.2
Reaction time trials on left1.01.53.01.71.21.41.00.6-1.2-1.11.51.20.3-1.31.4
Reaction time mean3.44.76.82.52.62.62.42.5-2.4-2.41.72.0-1.8-1.61.1
Reaction time mean AUC3.95.37.52.72.72.72.52.5-2.6-2.31.82.2-1.7-1.91.3
Median of all reaction times2.93.96.82.22.62.32.32.3-2.1-2.21.41.6-1.9-1.30.7
Reaction time omissions2.23.05.42.21.31.81.31.1-1.9-1.92.11.8-0.2-1.92.3
Reaction time false alarm rate0.91.32.5-0.6-1.2-1.2-1.0-0.91.11.3-1.1-1.60.41.0-1.4
Reaction time premature initiation rate0.10.10.7-0.3-0.1-0.2-0.5-0.40.30.40.1-0.90.30.3-0.1
Reaction time premature initiations0.10.10.30.30.20.2-0.0-0.1-0.00.10.5-0.40.4-0.00.4
Std. dev. reaction times3.75.28.12.92.12.62.22.3-2.5-2.62.12.4-1.4-2.02.0
Reaction time trials completed1.01.53.01.71.21.41.00.6-1.2-1.11.51.20.3-1.31.4
Reaction time trials AUC1.01.52.71.61.21.41.00.6-1.2-1.11.61.10.3-1.41.4
Run reversals in cocaine runway, females0.60.61.9-0.5-0.6-0.8-0.30.20.50.8-1.4-0.3-0.51.1-0.9
Run reversals in cocaine runway, males1.00.92.10.70.80.81.11.0-1.1-1.00.61.2-1.4-0.90.7
Latency to leave start box in cocaine runway4.54.99.0-3.0-2.1-2.3-2.0-1.72.42.2-2.2-2.11.12.9-1.7
Latency to leave start box in cocaine runway, F5.05.510.0-3.2-2.5-2.5-2.1-1.82.72.3-2.4-2.01.13.0-1.8
Latency to leave start box in cocaine runway, M0.90.91.7-0.9-0.7-0.9-1.3-1.10.81.0-0.4-1.31.20.7-0.4
Std. dev. time between licks in bursts0.30.41.1-0.6-0.9-0.5-0.8-1.10.20.40.3-0.20.6-0.20.6
Total sessions with >9 infusions2.42.76.31.71.71.72.02.5-1.5-1.40.41.9-2.3-0.50.2
Short access day 1 total inactive lever presses2.12.45.61.32.21.72.12.4-1.5-1.40.41.0-2.00.0-0.0
Short access day 10 total inactive lever presses1.41.63.31.01.81.41.81.7-1.1-1.20.40.6-1.8-0.0-0.4
Short access day 1 total infusions1.81.93.81.71.91.61.51.9-1.5-1.40.71.3-1.0-0.10.4
Short access day 10 total infusions0.20.20.70.40.30.40.40.5-0.4-0.50.20.8-0.6-0.30.5
Short access total infusions0.80.92.40.91.01.01.11.6-0.8-0.90.31.1-1.30.20.4
Short access day 1 locomotion0.91.03.70.81.91.21.11.3-0.9-0.80.30.5-1.0-0.4-0.4
Short access day 10 total locomotion0.60.61.20.80.50.70.80.9-1.0-0.60.61.1-0.8-0.50.9
Short access total locomotion1.81.83.41.31.91.61.51.8-1.6-1.20.91.2-1.5-0.60.6
One hour access (0.3 mA shock)0.40.42.00.71.40.80.70.4-0.6-0.60.5-0.50.3-0.0-0.4
Compulsive drug intake0.20.20.6-0.40.6-0.2-0.1-0.10.10.3-0.4-0.7-0.20.1-0.8
One hour access (shock baseline)0.70.81.71.11.31.11.11.0-0.9-1.00.70.4-0.30.00.1
Social response proportion0.91.02.40.60.81.00.90.5-1.2-1.51.21.2-0.6-0.71.3
Social responses1.52.06.8-0.3-1.5-1.0-1.9-2.40.50.60.9-1.02.6-0.51.3
Social time0.40.61.4-0.7-0.9-0.6-0.9-1.20.70.40.4-0.71.1-0.10.8
Soleus weight0.41.23.11.80.10.7-0.3-0.5-0.9-0.71.60.31.6-1.21.5
Bone: stiffness0.71.02.31.51.11.31.11.0-1.1-1.01.10.3-0.8-0.80.4
Tibialis anterior weight0.51.64.90.51.20.90.2-1.0-1.5-1.52.2-0.21.3-1.71.0
Time to tail flick, vehicle, before self-admin1.51.67.40.80.80.61.71.0-1.0-0.70.11.5-2.7-1.30.1
Time to tail flick, vehicle, after self-admin3.33.56.02.01.02.01.51.7-2.1-2.22.02.4-0.9-1.72.4
Time to tail flick, test, before self-admin0.80.81.61.10.50.91.11.3-1.0-0.70.41.0-0.8-0.70.5
Time to tail flick, test, after self-admin0.10.10.4-0.20.10.10.50.6-0.3-0.2-0.4-0.1-0.30.6-0.4
Delta time to tail flick, vehicle, before/after SA0.70.74.50.4-0.50.3-0.9-0.2-0.1-0.40.90.12.10.21.4
Delta time to tail flick, test, before/after SA0.10.10.3-0.20.40.20.0-0.3-0.3-0.50.4-0.40.60.30.3
Tibia length2.46.711.63.42.83.02.21.6-2.8-3.33.21.7-0.9-2.71.9
Ambulatory time before self-admin0.20.20.50.60.20.70.10.4-0.3-0.60.70.00.4-0.40.5
Ambulatory time after self-admin0.40.41.3-0.80.3-0.3-0.00.00.70.6-0.6-1.10.00.6-1.2
Bone: tissue strength0.20.20.6-0.60.0-0.3-0.3-0.40.40.2-0.3-0.80.40.6-0.6
Total heroin consumption0.40.41.40.50.00.60.70.9-0.4-0.50.30.9-1.2-0.10.5
Bone: trabecular number0.40.61.4-1.00.8-0.10.90.5-0.0-0.1-0.7-0.4-1.10.9-1.2
Bone: trabecular spacing0.10.10.4-0.2-0.10.20.30.40.3-0.6-0.20.3-0.60.20.1
Bone: trabecular thickness0.30.30.5-0.7-0.6-0.6-0.4-0.70.60.7-0.4-0.70.30.3-0.5
Bone: trabecular tissue density0.40.61.5-0.8-0.8-0.6-0.7-0.51.10.5-0.5-1.20.81.0-0.3
Water consumed over 24 hours1.51.84.62.00.91.31.02.2-1.3-1.10.12.1-1.1-0.40.4
Number of responses in last shaping day0.50.52.00.3-0.20.4-0.1-0.0-0.7-0.31.00.90.1-1.11.4