Hub : Genes

LOC102548590

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Liver gene expression LOC102548590 0.49 0.11 0.0e+00 0.37 0.26 0.37 0.28 5.0e-43 1.8e-28 1.3e-42 1.2e-31
2 RMTg gene expression LOC102548590 0.21 0.1 2.5e-04 0.09 0.1 0.13 0.12 1.9e-03 1.1e-03 2.9e-04 5.0e-04
3 Brain gene expression LOC102548590 0.12 0.06 1.6e-08 0.08 0.05 0.04 0.05 3.8e-08 3.6e-05 7.3e-05 1.1e-05
4 Adipose gene expression LOC102548590 0.14 0.08 1.3e-09 0.09 0.06 0.09 0.09 1.5e-10 7.7e-07 1.1e-09 2.8e-10
5 Liver intron excision ratio chr7_84132029_84136265 0.05 0.03 9.3e-06 0.01 0.03 0.02 0.02 7.0e-03 4.0e-04 1.1e-03 1.3e-03
6 NAcc gene expression LOC102548590 0.05 0.02 3.4e-09 0.07 0.06 0.06 0.06 3.5e-10 2.1e-09 3.9e-09 1.8e-09
7 PL gene expression LOC102548590 0.09 0.05 8.1e-09 0.09 0.08 0.08 0.08 3.9e-10 5.6e-09 3.3e-09 1.9e-09
8 Adipose mRNA stability LOC102548590 0.03 0.02 3.4e-04 0.03 0.03 0.03 0.03 5.1e-04 3.3e-04 6.3e-04 6.7e-04
9 BLA gene expression LOC102548590 0.15 0.07 4.1e-06 0.09 0.1 0.08 0.08 2.2e-05 7.6e-06 3.5e-05 3.4e-05
10 Liver intron excision ratio chr7_84127903_84136258 0.04 0.02 8.7e-04 0.03 0.01 0.01 0.02 1.1e-04 6.9e-03 1.4e-02 9.9e-04
11 IC gene expression LOC102548590 0.13 0.06 7.0e-06 0.13 0.12 0.12 0.13 5.0e-06 6.7e-06 6.5e-06 3.3e-06
12 OFC gene expression LOC102548590 0.29 0.12 1.4e-04 0.08 0.15 0.14 0.11 6.0e-03 2.5e-04 4.0e-04 1.3e-03

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12
Bone: apparent density0.20.41.2-0.80.80.0-0.10.80.10.40.5-0.51.1-0.2-1.0
Area under the delay curve1.21.42.30.7-1.3-1.2-1.2-1.3-1.4-1.50.8-0.8-1.5-1.2-0.9
BMI with tail4.415.025.6-5.14.34.14.13.13.93.7-4.34.11.94.52.2
BMI without tail1.65.011.8-3.42.62.12.01.72.22.2-2.62.50.92.40.8
Body weight4.519.636.1-6.04.94.94.73.64.54.5-4.84.82.44.22.3
Weight adjusted by age0.40.71.5-1.00.30.80.9-0.20.80.7-1.01.2-0.11.10.8
Bone surface0.30.61.7-1.21.10.60.61.00.40.60.2-0.31.3-0.2-0.7
Bone volume0.20.41.2-0.30.5-0.2-0.20.5-0.30.00.9-0.91.0-0.5-1.1
Breakpoint value in progressive ratio session1.31.54.7-0.81.90.80.91.91.01.2-0.60.22.21.20.2
Number of licking bursts0.60.92.31.4-1.3-0.9-0.4-1.0-0.8-1.10.5-0.4-1.5-0.7-0.0
Context. condit. distance diff. score0.40.51.4-1.10.41.20.60.20.40.4-0.90.8-0.60.30.4
Locomotion velocity, session 10.40.51.91.0-0.9-0.3-0.4-1.0-0.4-0.40.10.1-1.4-0.10.4
Locomotion distance, session 11.82.36.72.1-2.1-1.4-1.4-2.2-1.3-1.30.5-0.1-2.6-0.40.3
Locomotion velocity, session 24.35.06.52.5-2.0-2.4-2.4-2.0-2.3-2.32.6-2.3-1.8-2.2-1.8
Locomotion distance, session 22.73.79.12.7-2.7-1.7-1.6-2.5-1.6-1.51.2-0.8-3.0-1.7-0.0
Locomotion velocity, session 30.91.12.9-0.50.51.71.30.50.90.8-1.21.3-0.10.81.4
Locomotion distance, session 30.70.73.1-0.60.21.81.30.90.70.5-0.80.5-0.4-0.10.9
Stereotopy head waving bouts, day 30.20.20.50.4-0.7-0.4-0.2-0.7-0.4-0.5-0.20.3-0.6-0.20.3
Stereotopy head waving duration, day 31.72.15.01.6-1.7-1.9-1.6-2.2-1.4-1.40.8-0.3-1.4-1.1-0.5
Locomotion velocity, session 70.10.10.5-0.30.20.70.20.00.20.2-0.20.30.10.20.1
Locomotion distance, session 70.30.41.2-0.10.01.10.70.20.60.7-0.60.6-0.30.21.0
Stereotopy head waving bouts, day 73.94.46.42.2-2.3-2.4-2.4-2.5-2.3-2.21.6-1.3-2.3-1.6-1.2
Stereotopy head waving duration, day 72.93.55.62.1-2.2-2.1-2.2-2.4-1.9-1.91.5-1.1-2.0-1.4-1.0
Locomotion velocity, session 80.40.41.80.9-0.8-0.0-0.2-1.1-0.5-0.5-0.00.3-1.3-0.10.5
Locomotion distance, session 80.81.26.61.2-1.5-0.2-0.6-1.4-0.8-0.80.10.0-2.6-0.60.5
Degree of sensitization distance0.40.41.4-0.10.3-0.10.1-0.00.70.9-0.60.80.61.20.7
Degree of sensitization stereotypy4.75.17.62.3-2.2-2.4-2.8-2.4-2.5-2.42.2-1.9-2.0-2.1-1.8
Conditioned locomotion0.10.20.60.4-0.10.20.4-0.30.20.1-0.40.5-0.30.70.8
Cocaine response after cond. corrected0.00.10.40.10.1-0.1-0.30.00.0-0.10.1-0.10.30.6-0.2
Cocaine response after cond. not corrected0.10.10.30.4-0.2-0.3-0.5-0.3-0.0-0.10.1-0.10.10.5-0.0
Cocaine response before conditioning0.10.20.60.2-0.6-0.1-0.1-0.6-0.0-0.0-0.10.2-0.8-0.60.3
Saline control response0.81.12.4-0.61.11.11.01.51.11.1-0.80.40.81.11.1
Bone: connectivity density0.61.03.6-1.21.40.60.61.50.70.90.1-0.31.90.3-0.5
Bone: cortical apparent density3.64.97.32.7-2.6-2.4-2.6-1.9-2.4-2.42.0-2.0-1.6-1.8-1.4
Bone: cortical area0.30.41.5-0.2-0.40.1-0.1-0.8-0.10.1-0.91.1-1.20.50.6
Bone: cortical porosity0.20.21.5-1.20.7-0.00.00.40.20.4-0.30.20.40.2-0.6
Bone: cortical porosity0.90.92.6-1.61.20.50.60.80.91.0-1.11.00.71.20.2
Bone: cortical thickness0.40.72.20.5-1.2-0.9-1.1-1.3-0.9-0.7-0.10.2-1.5-0.1-0.1
Bone: cortical thickness0.10.10.5-0.2-0.00.10.2-0.40.20.3-0.50.70.10.70.3
Bone: cortical tissue density3.85.17.52.7-2.6-2.5-2.7-1.9-2.5-2.52.1-2.1-1.6-1.9-1.6
Condit. Reinf. active minus inactive responses0.70.81.9-0.40.20.91.20.61.11.0-1.10.9-0.20.81.4
Condit. Reinf. active-inactive response ratio0.10.10.4-0.0-0.2-0.20.10.2-0.2-0.10.2-0.7-0.3-0.4-0.3
Condit. Reinf. active responses1.41.74.5-0.50.11.61.70.51.41.2-1.61.5-0.90.92.1
Condit. Reinf. inactive responses1.82.36.5-0.3-0.12.01.80.11.51.2-1.82.1-1.20.92.6
Incentive salience index mean0.50.71.3-0.60.41.01.10.90.90.8-1.00.7-0.00.51.1
Condit. Reinf. lever presses0.10.10.4-0.2-0.00.40.40.70.20.2-0.30.0-0.1-0.40.3
Condit. Reinf. active minus inactive responses1.62.13.4-1.21.31.71.80.81.61.6-1.51.80.91.11.6
Condit. Reinf. active-inactive response ratio3.64.25.4-1.92.22.22.31.42.32.3-2.02.31.72.01.7
Condit. Reinf. active responses0.40.51.6-0.30.10.70.9-0.10.60.6-1.01.2-0.4-0.21.1
Condit. Reinf. inactive responses1.82.35.71.4-1.8-1.4-1.3-1.3-1.5-1.71.0-1.1-1.8-2.4-0.8
Condit. Reinf. lever presses0.40.62.00.6-0.8-0.6-0.4-0.8-0.8-0.90.6-0.5-0.6-1.4-0.4
Condit. Reinf. lever reinforcers received0.20.20.6-0.0-0.30.30.5-0.40.10.1-0.60.8-0.7-0.60.7
Conditioned reinforcement - actives0.61.02.4-1.61.21.11.11.01.21.1-0.90.90.10.80.2
Conditioned reinforcement - inactives0.50.81.9-1.40.41.11.00.21.01.0-1.01.0-0.70.00.5
Conditioned locomotion2.43.14.9-2.21.71.91.91.62.12.0-1.91.80.31.61.2
Patch foraging indifference point 0 sec1.12.02.8-1.51.21.41.41.31.71.6-1.71.40.71.61.2
Patch foraging indifference point AUC0.81.13.40.10.21.01.00.51.01.1-1.51.4-0.31.11.9
Delay disc. indifference point, 0s delay0.10.10.8-0.90.10.30.3-0.2-0.1-0.20.00.00.0-0.4-0.2
Delay disc. indifference point, 16s delay1.61.82.91.0-1.7-1.4-1.4-1.7-1.4-1.51.0-0.8-1.6-1.0-1.0
Delay disc. indifference point, 2s delay1.92.23.01.1-1.5-1.5-1.6-1.5-1.7-1.71.3-1.3-1.5-1.6-1.1
Delay disc. indifference point, 24s delay1.71.94.21.5-2.0-1.1-1.2-2.1-1.4-1.50.8-0.5-2.1-0.9-0.2
Delay disc. indifference point, 4s delay0.60.71.50.3-0.9-0.7-0.7-1.0-0.8-0.90.4-0.4-1.2-1.2-0.5
Delay disc. indifference point, 8s delay0.10.10.8-0.4-0.1-0.1-0.20.0-0.4-0.3-0.3-0.0-0.9-0.1-0.3
Indifference point function ln k0.10.20.6-0.70.1-0.2-0.2-0.4-0.4-0.40.3-0.10.0-0.1-0.8
Indifference point function log k0.10.20.6-0.70.1-0.2-0.2-0.4-0.4-0.40.3-0.10.0-0.1-0.8
Patch foraging total patch changes 0 sec0.71.32.1-1.10.81.11.10.71.41.3-1.51.40.51.41.2
Patch foraging total patch changes 12 sec0.30.41.40.30.40.30.21.20.50.5-0.60.10.51.00.7
Patch foraging total patch changes 18 sec0.71.12.2-0.90.81.01.00.91.31.2-1.51.30.20.81.2
Patch foraging total patch changes 24 sec0.20.41.31.1-0.8-0.6-0.6-0.3-0.6-0.60.4-0.6-0.5-0.60.1
Patch foraging total patch changes 6 sec0.50.72.50.40.10.70.50.60.91.0-1.10.80.11.11.6
Patch foraging time to switch 0 sec0.71.43.00.7-0.2-1.2-1.20.1-1.3-1.11.6-1.70.5-1.3-1.6
Patch foraging water rate 0 sec0.61.43.5-0.40.31.00.9-0.41.11.1-1.61.9-0.31.61.7
Patch foraging water rate 12 sec0.20.40.7-0.80.80.90.60.10.50.5-0.50.70.70.80.3
Patch foraging water rate 18 sec1.72.74.7-1.01.21.91.60.72.02.2-1.71.91.31.52.0
Patch foraging water rate 24 sec0.50.71.80.10.20.50.60.11.11.1-0.91.00.41.11.3
Patch foraging water rate 6 sec0.81.23.4-0.80.41.01.1-0.51.31.2-1.41.9-0.40.61.4
Seeking ratio, delayed vs. immediate footshock0.20.31.0-1.00.90.60.40.40.40.4-0.10.10.70.3-0.1
Distance traveled before self-admin0.20.20.80.6-0.6-0.2-0.1-0.20.10.2-0.40.3-0.90.60.6
Distance traveled after self-admin0.20.20.70.2-0.2-0.8-0.8-0.0-0.5-0.50.4-0.4-0.1-0.2-0.7
Extensor digitorum longus weight1.55.914.2-1.91.32.42.10.43.13.1-3.03.80.42.32.7
Bone: elastic displacement2.32.65.71.4-2.0-1.8-1.7-2.4-1.4-1.41.2-0.8-1.9-1.9-0.9
Bone: elastic work0.70.92.80.4-1.1-1.1-1.1-1.7-0.9-0.80.30.0-1.5-0.7-0.5
Bone: endosteal estimation0.71.52.8-1.31.51.71.51.61.11.2-0.80.81.30.50.6
Bone: endosteal perimeter0.30.71.2-1.10.71.11.10.50.60.6-1.11.1-0.30.40.7
Epididymis fat weight1.03.45.4-2.01.91.81.92.31.71.8-1.91.51.52.21.3
Delta time in closed arm before/after self-admin1.21.11.70.7-0.7-1.3-1.3-0.5-1.3-1.31.0-1.2-0.4-1.3-1.3
Delta time in open arm before/after self-admin0.10.10.4-0.70.30.30.3-0.10.50.4-0.00.30.30.3-0.1
Diff in mean of infusions in LGA sessions0.10.10.3-0.00.30.60.6-0.10.60.60.10.10.3-0.20.5
Delay discount exponential model param1.41.62.4-0.81.41.31.31.31.51.6-0.91.01.61.31.0
Extinction: sum of active levers before priming0.30.30.50.60.0-0.7-0.70.2-0.5-0.40.6-0.70.30.4-0.7
Active lever presses in extinction session 60.30.30.70.3-0.2-0.7-0.6-0.1-0.8-0.70.6-0.8-0.3-0.5-0.7
Bone: final force0.71.12.1-1.51.00.90.50.80.81.1-1.41.30.61.40.5
Bone: final moment0.20.41.2-1.10.60.50.00.40.30.6-0.90.90.20.90.1
Food consumed during 24 hour testing period0.30.40.80.00.90.70.90.80.70.6-0.20.20.70.10.7
Glucose1.11.72.8-1.31.51.61.41.71.51.5-0.90.51.41.20.8
Heart weight0.50.71.90.10.0-1.1-1.2-0.2-1.2-1.10.7-0.8-0.1-0.1-1.4
Delay discount hyperbolic model param1.82.03.0-1.01.51.51.61.41.71.7-1.11.11.61.51.2
Intermittent access intake day 1-15 change0.40.82.60.9-1.3-1.0-1.0-1.3-0.7-0.70.4-0.3-1.6-0.2-0.2
Intermittent access intake escalation0.51.12.21.1-1.3-1.2-1.2-1.2-1.0-1.00.7-0.6-1.5-0.4-0.6
Intermittent access intake escalation 21.11.33.70.8-1.5-1.1-1.2-1.7-1.0-1.00.6-0.4-1.9-0.4-0.7
Intermitt. access day 1 inactive lever presses0.10.41.4-1.20.90.80.70.60.50.5-0.50.40.70.30.0
Intermitt. access day 15 inactive lever presses1.12.23.1-1.81.31.61.60.81.61.6-1.61.71.11.51.4
Intermitt. access escalation Index0.30.51.50.10.60.70.60.40.70.7-0.60.70.30.91.2
Intermittent access day 1 total infusions0.71.13.0-1.11.50.91.01.70.90.9-0.3-0.01.60.2-0.0
Intermittent access day 15 total infusions0.10.10.40.1-0.0-0.4-0.4-0.0-0.3-0.30.5-0.50.0-0.2-0.7
Intermittent access terminal intake (last 3 days)0.00.10.20.2-0.2-0.3-0.2-0.2-0.1-0.10.1-0.1-0.5-0.2-0.2
Intermittent access total infusions0.10.20.4-0.60.60.10.20.60.30.30.0-0.10.4-0.2-0.6
Intermittent access day 1 locomotion1.62.03.8-1.62.01.41.41.91.51.5-1.00.81.61.10.4
Intermittent access day 15 total locomotion0.40.71.1-1.00.10.91.00.11.00.9-1.01.0-1.00.30.8
Intermittent access total locomotion1.11.32.0-1.40.81.11.30.71.31.3-1.41.4-0.20.91.0
Intermittent access standard deviation0.10.20.5-0.5-0.20.10.1-0.70.10.0-0.40.7-0.7-0.0-0.0
Left kidney weight0.52.36.3-1.82.31.21.12.31.11.0-0.70.72.51.4-0.4
Right kidney weight1.04.59.7-3.03.01.91.92.61.71.6-1.31.33.11.7-0.2
Cocaine induced anxiety0.30.50.90.8-0.6-0.5-0.7-0.8-0.7-0.70.8-0.6-0.1-1.0-0.7
Post-drug Anxiety0.91.02.10.7-0.9-0.9-1.0-0.8-1.0-1.01.1-1.1-0.5-1.5-1.1
Baseline Anxiety0.30.30.80.9-0.5-0.7-0.8-0.3-0.4-0.50.6-0.6-0.5-0.4-0.1
Tail length0.41.53.8-0.0-0.8-1.3-1.5-1.2-1.4-1.21.0-0.9-0.8-2.0-1.8
Length with tail0.52.05.3-2.31.41.61.50.81.41.6-1.61.80.60.40.4
Length without tail2.58.213.6-2.72.33.53.41.53.13.2-3.23.71.32.62.8
Times rat made contact with spout0.20.31.10.4-0.2-0.2-0.01.1-0.1-0.20.3-1.0-0.1-0.7-0.3
Lifetime Intake0.40.51.3-1.01.00.60.71.20.70.7-0.30.10.7-0.0-0.3
Liver weight, left1.72.85.8-2.42.01.71.71.81.71.7-1.61.51.31.10.6
Liver weight, right2.34.16.4-2.51.62.12.21.42.32.4-2.52.40.71.61.7
Locomotor activity2.53.96.3-2.52.41.91.92.01.91.8-2.32.01.52.01.1
Locomotor testing distance1.42.53.7-1.91.91.51.51.61.61.4-1.71.51.71.30.9
Locomotor testing rearing1.12.34.5-1.91.81.31.42.11.61.4-1.41.01.41.50.6
Locomotion in novel chamber0.50.61.6-0.81.30.70.71.10.60.7-0.70.40.90.50.1
Locomotion in novel chamber post-restriction0.30.51.60.5-0.1-0.9-0.80.6-0.7-0.80.7-1.30.4-0.3-0.8
Fecal boli incidents, locomotor time 10.71.03.10.7-1.4-0.9-0.9-1.8-0.9-0.80.6-0.3-1.4-1.0-0.2
Change in fecal boli incidents, locomotor task0.80.81.4-0.51.11.11.20.81.21.1-0.60.60.80.11.0
Time >=10cm from walls, locomotor time 11.71.83.5-1.41.01.41.50.41.51.5-1.71.90.60.51.6
Bouts of movement, locomotor time 10.20.21.2-1.10.40.40.40.20.20.10.0-0.10.5-0.4-0.8
Total resting periods, locomotor time 10.10.20.8-0.90.00.30.3-0.30.20.00.10.0-0.0-0.7-0.6
Rest time, locomotor task time 10.10.10.2-0.3-0.4-0.1-0.1-0.1-0.2-0.30.3-0.4-0.1-0.2-0.5
Distance moved, locomotor task time 10.60.91.40.9-0.8-1.2-1.2-1.1-1.0-0.90.8-0.5-0.9-1.1-0.8
Vertical activity count, locomotor time 10.20.40.91.0-0.7-0.7-0.7-0.7-0.5-0.40.2-0.2-0.9-0.70.1
Time >=10cm from walls, locomotor time 23.24.87.6-2.82.62.42.42.32.42.3-2.01.82.11.41.0
Bouts of movement, locomotor time 20.40.61.30.5-1.1-0.8-0.7-1.0-0.8-0.80.3-0.2-1.1-0.6-0.5
Total resting periods, locomotor time 20.40.81.70.7-1.3-0.9-0.9-1.1-0.9-0.90.4-0.4-1.1-0.8-0.4
Rest time, locomotor task time 21.31.72.81.7-1.3-1.4-1.3-1.3-1.3-1.31.5-1.3-0.3-1.4-0.5
Distance moved, locomotor task time 20.20.21.0-1.00.40.30.20.30.30.4-0.50.40.10.2-0.4
Vertical activity count, locomotor time 20.81.02.6-1.61.21.00.91.20.90.9-1.10.80.91.0-0.0
Light reinforcement 10.92.14.41.5-1.5-1.9-2.1-1.2-1.4-1.41.1-1.1-1.0-1.7-1.0
Light reinforcement 20.20.31.00.30.1-0.6-0.70.4-0.5-0.30.7-1.00.4-0.2-0.8
Bone: marrow area0.81.73.2-1.41.61.81.61.61.31.3-0.90.91.30.50.7
Bone: maximum diameter0.91.72.9-1.31.11.61.50.81.21.2-1.61.70.21.31.3
Bone: maximum force0.71.22.5-1.40.91.10.70.60.81.1-1.51.60.51.30.7
Bone: maximum moment0.30.51.4-1.00.50.70.30.20.40.6-1.01.20.10.80.3
Mean time between licks in bursts0.10.10.5-0.1-0.5-0.3-0.2-0.7-0.1-0.40.00.1-0.7-0.4-0.3
Mean num. licks in bursts0.20.41.2-0.80.70.3-0.11.00.30.50.2-0.51.1-0.2-0.5
Cd content in liver3.43.79.61.9-2.5-1.9-1.7-3.1-1.8-1.81.1-0.6-2.8-1.7-0.3
Co content in liver1.11.23.51.1-1.4-1.1-0.9-1.9-1.1-1.10.40.0-1.7-0.6-0.2
Cu content in liver0.30.31.3-1.20.8-0.10.00.90.30.2-0.1-0.10.80.2-0.7
Fe content in liver0.60.71.4-0.20.71.20.90.70.91.1-0.80.80.60.61.1
K content in liver3.93.86.5-1.92.22.22.12.62.02.0-1.81.42.01.51.3
Mg content in liver1.11.13.5-1.01.31.01.01.91.10.9-0.50.11.50.60.2
Mn content in liver0.70.82.1-1.01.20.80.81.50.90.9-0.80.50.90.60.3
Na content in liver3.73.910.4-2.22.61.92.23.21.81.8-1.00.42.81.00.3
Rb content in liver0.30.31.2-0.40.70.0-0.00.90.50.5-0.0-0.11.10.5-0.1
Se content in liver0.40.51.7-1.30.71.10.80.90.70.4-0.50.00.2-0.50.1
Sr content in liver0.30.31.0-1.00.80.30.10.7-0.0-0.4-0.0-0.00.4-0.1-0.8
Zn content in liver1.82.03.8-1.91.41.81.61.81.61.4-1.30.90.90.90.7
Bone: minimum diameter1.12.04.7-1.60.91.41.30.71.41.5-2.12.2-0.21.21.5
Time in familiar zone, hab. session 10.70.71.31.1-0.8-0.6-0.5-1.1-0.9-1.01.0-0.7-0.7-1.2-0.3
Time in novel zone, hab. session 10.70.71.5-1.20.90.50.51.00.80.8-0.80.61.21.00.2
Total zone transitions, hab. session 12.43.311.21.9-2.6-1.3-1.4-3.2-1.2-1.00.10.6-3.3-1.00.7
Total locomotion distance, hab. session 11.21.74.40.3-0.80.60.5-1.70.50.5-1.62.1-1.80.82.1
Locomotion velocity, hab. session 11.01.45.10.8-1.30.20.1-1.8-0.00.0-1.11.5-2.30.41.6
Time in familiar zone, hab. session 21.71.83.92.0-1.3-1.1-1.5-1.3-1.3-1.31.4-1.3-0.9-1.4-0.6
Time in novel zone, hab. session 21.91.94.4-2.11.01.31.70.61.31.3-1.71.80.31.41.0
Total zone transitions, hab. session 21.92.56.02.4-2.3-1.0-1.4-2.1-1.4-1.40.7-0.4-2.3-1.10.5
Total locomotion distance, hab. session 20.60.72.01.4-1.2-0.2-0.4-1.2-0.3-0.3-0.40.6-1.30.01.2
Locomotion velocity, hab. session 20.50.72.21.5-1.2-0.3-0.5-1.1-0.4-0.5-0.10.3-1.2-0.10.9
Novel to familiar place preference ratio0.70.82.0-1.10.41.21.40.41.01.1-0.90.9-0.30.10.8
Novelty place preference0.60.61.5-1.10.51.01.20.40.91.0-0.80.7-0.10.20.6
Time in novel zone, NPP test0.70.71.7-1.10.51.11.30.31.01.1-0.80.9-0.20.30.7
Total zone transitions, NPP test1.21.87.51.7-1.8-0.6-0.7-1.9-0.5-0.5-0.40.9-2.70.21.3
Total locomotion distance, NPP test0.91.33.90.6-0.60.50.6-1.00.60.5-1.31.7-1.61.02.0
Locomotion velocity, NPP test0.91.33.90.8-0.70.30.4-0.90.50.4-1.31.7-1.61.22.0
Intraocular pressure0.20.21.3-0.2-0.50.50.6-0.50.10.3-0.40.4-1.1-0.00.4
Delta distance traveled before/after self-admin0.20.20.8-0.80.6-0.1-0.10.4-0.0-0.10.1-0.10.9-0.1-0.7
Delta ambulatory time before/after self-admin0.10.20.8-0.50.6-0.0-0.10.50.0-0.0-0.00.00.90.1-0.4
Parametrial fat weight4.811.220.4-4.53.73.73.43.83.43.4-3.52.92.42.81.7
Pavlov. Cond. lever latency0.00.00.1-0.30.10.3-0.0-0.20.30.20.10.10.1-0.1-0.1
Pavlov. Cond. magazine entry latency0.20.30.8-0.30.0-0.3-0.20.5-0.2-0.20.5-0.90.7-0.9-0.8
Pavlov. Cond. change in total contacts0.40.50.90.8-0.8-0.7-0.4-0.6-0.9-0.90.6-0.7-0.6-0.4-0.2
Pavlov. Cond. index score0.10.20.50.3-0.3-0.7-0.40.1-0.6-0.50.4-0.60.1-0.4-0.4
Pavlov. Cond. latency score0.20.30.80.7-0.5-0.9-0.5-0.1-0.7-0.70.4-0.6-0.1-0.3-0.3
Pavlov. Cond. lever contacts0.10.20.50.5-0.3-0.7-0.40.1-0.7-0.50.2-0.4-0.0-0.1-0.2
Pavlov. Cond. magazine entry number0.10.20.40.5-0.10.0-0.1-0.60.00.0-0.20.6-0.50.50.5
Pavlov. Cond. intertrial magazine entries1.51.83.5-0.90.91.61.40.61.31.2-1.71.8-0.01.91.7
Pavlov. Cond. lever-magazine prob. diff.0.10.10.2-0.10.0-0.30.00.5-0.3-0.20.2-0.50.4-0.3-0.3
Pavlov. Cond. response bias0.10.20.5-0.50.1-0.2-0.00.6-0.3-0.20.2-0.60.3-0.5-0.7
Pavlov. Cond. lever latency0.40.61.8-0.90.70.60.40.50.90.8-0.80.80.41.30.3
Pavlov. Cond. magazine entry latency0.40.41.9-0.50.80.1-0.01.10.1-0.00.4-0.71.4-0.3-0.8
Pavlov. Cond. change in total contacts0.10.11.0-0.30.2-0.10.0-0.3-0.1-0.20.20.00.3-1.0-0.4
Pavlov. Cond. index score0.10.20.60.20.2-0.1-0.10.3-0.3-0.30.5-0.60.7-0.8-0.4
Pavlov. Cond. latency score0.10.20.50.20.2-0.2-0.10.3-0.3-0.30.5-0.60.7-0.7-0.5
Pavlov. Cond. lever contacts0.60.82.21.2-0.9-0.8-0.6-0.6-1.0-1.00.9-1.0-0.4-1.5-0.4
Pavlov. Cond. magazine entry number0.81.02.91.1-1.5-0.9-0.8-1.3-0.9-0.80.6-0.5-1.7-0.5-0.2
Pavlov. Cond. intertrial magazine entries0.30.51.5-1.00.50.71.20.90.40.4-0.70.4-0.30.70.3
Pavlov. Cond. lever-magazine prob. diff.0.10.20.8-0.00.50.00.10.6-0.1-0.10.3-0.50.9-0.6-0.3
Pavlov. Cond. response bias0.20.21.00.5-0.5-0.3-0.2-0.2-0.5-0.60.4-0.5-0.2-1.0-0.1
Time in closed arm before self-admin0.40.51.3-0.60.70.70.80.80.60.6-0.50.51.01.10.3
Time in closed arm after self-admin0.60.71.10.7-0.7-0.8-0.8-0.4-1.0-1.01.0-1.1-0.0-0.9-0.9
Time in open arm before self-admin0.10.10.50.0-0.1-0.00.0-0.3-0.2-0.1-0.1-0.0-0.7-0.50.1
Time in open arm after self-admin0.20.30.70.10.00.30.4-0.50.50.6-0.50.7-0.60.30.8
Bone: periosteal estimation0.30.61.2-0.90.71.00.80.60.60.7-1.01.10.10.50.7
Bone: periosteal perimeter0.20.41.2-0.1-0.00.60.5-0.20.10.2-1.01.1-0.90.71.0
Bone: post-yield work1.01.42.5-0.91.11.61.31.31.01.0-1.31.21.21.11.3
Progressive ratio test 1 active lever presses2.32.84.3-1.92.01.82.11.52.01.9-1.31.41.70.81.1
Progressive ratio test 1 breakpoint2.22.74.2-1.92.01.82.01.52.01.9-1.31.41.60.81.1
Progressive ratio test 1 inactive lever presses0.50.71.1-1.01.00.80.90.91.01.0-0.70.60.80.70.5
Progressive ratio test 2 active lever presses1.01.21.8-1.41.01.11.30.81.31.3-1.21.20.21.00.7
Progressive ratio test 2 breakpoint0.91.01.7-1.30.91.01.20.81.21.2-1.11.10.10.90.6
Progressive ratio test 2 inactive lever presses0.30.51.1-1.00.50.70.70.30.90.9-0.90.8-0.20.70.5
Incentive Sensitization - Responses0.10.20.6-0.70.10.30.40.40.30.3-0.60.4-0.70.60.1
Incentive Sensitization - Breakpoint0.10.10.7-0.5-0.10.10.20.20.10.1-0.40.2-0.90.4-0.1
Sum of active levers in priming session hrs 5-60.20.20.7-0.80.60.20.20.30.50.6-0.50.50.10.2-0.1
Progressive ratio2.33.75.21.5-2.2-2.1-2.2-2.2-2.1-2.01.5-1.4-2.3-1.8-1.3
Food seeking constrained by brief footshock0.70.82.3-0.20.21.10.90.11.11.1-0.91.10.20.81.5
Seeking ratio, punishment vs. effort3.85.58.2-1.92.32.72.72.12.92.7-2.22.22.02.32.1
Retroperitoneal fat weight1.77.315.9-4.03.52.22.23.12.82.8-2.62.22.32.50.7
Reaction time number correct0.51.02.0-0.80.71.21.10.40.90.9-1.41.4-0.10.81.4
Reaction time mean minus median1.02.43.2-1.51.61.61.81.61.71.7-1.81.50.81.51.5
Reaction time mean minus median AUC0.10.30.7-0.70.80.40.50.90.50.5-0.40.20.50.20.2
Reaction time num false alarms0.20.31.00.1-0.30.3-0.1-0.3-1.0-1.00.4-0.4-0.4-0.4-0.6
Reaction time num false alarms AUC0.20.20.90.0-0.30.50.0-0.3-0.9-0.90.2-0.3-0.6-0.3-0.5
Reaction time trials correct on left0.51.02.0-0.80.71.21.10.40.90.9-1.41.4-0.10.81.4
Reaction time trials on left0.71.42.7-1.00.91.41.20.51.11.1-1.61.6-0.01.01.5
Reaction time mean3.65.77.3-2.72.62.52.62.62.62.5-2.32.02.12.31.5
Reaction time mean AUC3.96.38.1-2.92.72.82.82.72.82.6-2.52.12.12.31.7
Median of all reaction times3.34.76.9-2.62.42.32.32.42.32.3-2.01.72.12.11.1
Reaction time omissions2.23.26.3-1.01.02.01.90.91.81.8-2.42.20.12.12.5
Reaction time false alarm rate0.71.02.20.5-0.9-0.4-0.7-0.8-1.4-1.51.1-1.0-0.7-1.0-1.3
Reaction time premature initiation rate0.10.10.30.1-0.2-0.5-0.5-0.3-0.5-0.4-0.10.1-0.20.2-0.0
Reaction time premature initiations0.10.10.4-0.10.1-0.1-0.1-0.1-0.2-0.1-0.60.5-0.10.50.5
Std. dev. reaction times3.25.87.3-2.32.32.62.72.32.62.6-2.72.41.42.42.3
Reaction time trials completed0.71.42.7-1.00.91.41.20.51.11.1-1.61.6-0.01.01.5
Reaction time trials AUC0.71.42.7-1.00.91.41.20.51.11.1-1.61.60.01.01.5
Run reversals in cocaine runway, females0.70.71.80.6-0.5-0.7-0.7-0.1-1.1-1.01.1-1.30.4-0.8-0.9
Run reversals in cocaine runway, males1.01.01.9-0.91.21.21.31.21.01.0-0.50.41.40.90.5
Latency to leave start box in cocaine runway4.85.47.12.1-2.4-2.7-2.6-2.0-2.6-2.62.6-2.5-1.2-2.1-2.2
Latency to leave start box in cocaine runway, F4.85.57.42.3-2.3-2.7-2.6-2.0-2.5-2.62.7-2.5-1.2-2.3-2.2
Latency to leave start box in cocaine runway, M1.01.01.90.8-1.4-1.0-1.1-1.1-1.1-1.20.8-0.7-1.0-0.6-0.6
Std. dev. time between licks in bursts0.40.51.71.0-1.1-0.4-0.3-1.1-0.2-0.50.10.2-1.3-0.40.5
Total sessions with >9 infusions2.02.54.8-2.02.01.61.82.21.71.6-1.20.91.50.80.6
Short access day 1 total inactive lever presses1.21.53.7-1.91.81.31.11.91.00.9-0.70.31.30.8-0.2
Short access day 10 total inactive lever presses0.40.91.9-1.41.31.00.81.20.70.8-0.80.51.01.3-0.0
Short access day 1 total infusions1.21.63.3-1.81.51.31.51.81.41.4-1.10.70.50.40.5
Short access day 10 total infusions0.60.81.3-0.61.10.91.01.01.11.1-0.70.61.00.00.8
Short access total infusions1.21.53.3-1.41.71.21.41.81.31.3-0.90.61.20.50.4
Short access day 1 locomotion1.82.24.7-2.21.91.61.71.81.81.7-1.21.11.10.50.3
Short access day 10 total locomotion0.91.73.1-0.71.61.41.31.51.31.3-1.00.91.81.21.2
Short access total locomotion2.02.54.2-1.82.01.71.82.11.61.5-1.31.11.50.90.8
One hour access (0.3 mA shock)0.70.83.0-1.70.90.80.80.80.80.9-0.80.7-0.20.9-0.3
Compulsive drug intake0.20.20.7-0.60.4-0.0-0.10.6-0.1-0.10.3-0.50.80.1-0.8
One hour access (shock baseline)0.20.30.8-0.90.70.60.60.60.60.7-0.60.5-0.10.30.1
Social response proportion0.80.92.2-0.40.60.70.70.51.21.3-1.01.10.41.51.2
Social responses1.52.06.81.6-2.1-0.6-0.8-2.4-0.8-0.7-0.30.8-2.6-0.21.2
Social time0.40.61.21.0-1.0-0.8-0.9-1.1-0.5-0.6-0.10.3-0.90.60.5
Soleus weight0.41.23.3-0.1-0.41.00.5-0.50.60.6-1.71.8-1.40.51.8
Bone: stiffness0.50.81.3-1.10.90.90.50.80.60.8-1.11.10.71.10.6
Tibialis anterior weight0.51.65.6-1.10.21.10.8-0.81.41.5-1.72.4-0.70.71.3
Time to tail flick, vehicle, before self-admin0.91.05.0-0.61.30.20.20.6-0.1-0.11.2-1.02.2-0.6-1.1
Time to tail flick, vehicle, after self-admin2.02.65.2-0.70.91.71.71.01.81.8-1.91.70.32.32.2
Time to tail flick, test, before self-admin0.10.10.2-0.50.40.0-0.00.5-0.00.1-0.10.00.30.2-0.4
Time to tail flick, test, after self-admin0.70.71.70.3-0.1-0.8-0.80.1-0.8-0.80.9-1.30.3-1.1-1.3
Delta time to tail flick, vehicle, before/after SA1.41.44.80.9-1.20.20.2-0.60.50.3-1.41.2-2.21.12.0
Delta time to tail flick, test, before/after SA0.10.10.2-0.10.00.30.40.10.30.3-0.40.2-0.2-0.00.4
Tibia length2.87.811.7-3.22.53.43.11.72.92.9-3.33.40.72.82.3
Ambulatory time before self-admin0.20.31.00.6-0.6-0.1-0.0-0.20.10.1-0.50.4-0.91.00.6
Ambulatory time after self-admin0.10.10.3-0.30.0-0.4-0.40.1-0.1-0.20.0-0.10.10.2-0.5
Bone: tissue strength0.10.10.3-0.2-0.1-0.1-0.3-0.3-0.1-0.10.2-0.2-0.50.1-0.4
Total heroin consumption0.30.41.1-0.10.60.30.40.60.50.7-0.50.50.81.00.6
Bone: trabecular number0.30.51.8-0.60.7-0.3-0.30.5-0.20.10.8-0.81.2-0.4-1.3
Bone: trabecular spacing0.10.10.30.20.1-0.4-0.10.20.10.10.1-0.20.40.6-0.1
Bone: trabecular thickness0.40.50.70.8-0.6-0.8-0.9-0.8-0.8-0.80.7-0.5-0.2-0.8-0.5
Bone: trabecular tissue density0.60.82.20.9-1.1-1.1-1.5-0.8-1.1-0.90.3-0.7-1.1-0.1-0.4
Water consumed over 24 hours0.71.04.2-0.61.21.11.22.01.11.0-0.6-0.10.70.10.6
Number of responses in last shaping day0.91.02.5-0.50.31.11.20.21.11.1-1.11.40.00.91.6