Hub : Genes

Prkag1

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Brain mRNA stability Prkag1 0.24 0.1 0.0e+00 0.34 0.34 0.35 0.36 9.3e-33 2.8e-32 3.8e-34 2.1e-34
2 PL gene expression Prkag1 0.41 0.17 0.0e+00 0.39 0.4 0.42 0.42 4.1e-46 2.0e-47 9.3e-50 2.8e-49
3 IL mRNA stability Prkag1 0.38 0.16 5.5e-09 0.22 0.27 0.29 0.3 6.0e-06 2.8e-07 1.2e-07 5.6e-08
4 pVTA mRNA stability Prkag1 0.21 0.13 1.1e-08 0.16 0.19 0.16 0.18 2.2e-07 1.7e-08 1.5e-07 3.3e-08
5 Adipose gene expression Prkag1 0.04 0.04 9.7e-05 0.03 0.03 0.03 0.03 1.2e-04 4.1e-04 7.9e-04 2.4e-04
6 NAcc intron excision ratio chr7_129975357_129980205 0.05 0.04 1.1e-05 0.04 0.04 0.03 0.04 2.4e-05 5.7e-05 9.3e-05 3.3e-05
7 RMTg gene expression Prkag1 0.52 0.22 2.2e-11 0.32 0.31 0.32 0.09 3.0e-09 6.0e-09 3.5e-09 2.4e-03
8 pVTA gene expression Prkag1 0.11 0.08 1.8e-04 0.08 0.08 0.08 0.08 3.3e-04 1.8e-04 3.4e-04 3.3e-04
9 OFC mRNA stability Prkag1 0.21 0.13 6.4e-05 0.14 0.14 0.12 0.14 3.1e-04 3.3e-04 1.0e-03 3.5e-04
10 OFC gene expression Prkag1 0.54 0.2 5.8e-08 0.18 0.21 0.21 0.22 4.2e-05 1.1e-05 9.5e-06 5.4e-06
11 LHb gene expression Prkag1 0.41 0.17 1.5e-09 0.34 0.28 0.33 0.33 7.8e-09 2.2e-07 1.4e-08 1.6e-08
12 PL mRNA stability Prkag1 0.26 0.12 0.0e+00 0.32 0.31 0.32 0.33 1.4e-35 3.4e-35 1.4e-36 5.4e-37
13 BLA gene expression Prkag1 0.22 0.12 1.4e-13 0.2 0.23 0.22 0.23 3.1e-11 9.4e-13 4.3e-12 1.1e-12
14 Liver mRNA stability Prkag1 0.12 0.07 0.0e+00 0.14 0.14 0.14 0.13 5.0e-15 7.7e-15 5.9e-15 1.4e-14
15 Brain gene expression Prkag1 0.39 0.13 0.0e+00 0.49 0.52 0.52 0.52 1.1e-51 4.0e-56 6.8e-56 3.5e-56
16 NAcc gene expression Prkag1 0.23 0.07 0.0e+00 0.38 0.38 0.38 0.39 5.9e-47 5.3e-46 4.4e-47 1.4e-47
17 IL gene expression Prkag1 0.46 0.18 7.4e-12 0.3 0.33 0.38 0.39 6.3e-08 1.1e-08 3.2e-10 2.5e-10
18 NAcc mRNA stability Prkag1 0.26 0.11 0.0e+00 0.32 0.33 0.33 0.33 2.2e-38 3.7e-39 4.8e-39 2.6e-39
19 BLA mRNA stability Prkag1 0.35 0.16 0.0e+00 0.4 0.38 0.4 0.4 1.0e-22 1.8e-21 1.7e-22 1.1e-22
20 RMTg mRNA stability Prkag1 0.19 0.17 5.0e-04 0.11 0.12 0.11 0.13 6.8e-04 3.3e-04 5.7e-04 2.9e-04
21 LHb mRNA stability Prkag1 0.35 0.14 1.3e-09 0.28 0.33 0.33 0.3 2.1e-07 1.1e-08 9.5e-09 5.9e-08
22 PL alternative TSS NM_013010.2 0.03 0.03 2.9e-03 0.01 0.01 0.01 0.01 1.1e-02 1.5e-02 1.0e-02 2.6e-02
23 Adipose mRNA stability Prkag1 0.21 0.12 1.9e-10 0.06 0.08 0.08 0.08 3.1e-07 4.3e-09 1.8e-09 6.3e-09
24 PL alternative TSS XM_006257331.4 0.02 0.02 3.9e-03 0.01 0.01 0.01 0.01 1.3e-02 1.3e-02 1.8e-02 2.5e-02

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24
Bone: apparent density10.417.520.44.34.44.44.34.34.34.3-4.3-4.3-4.34.34.4-4.1-4.3-4.2-4.3-4.34.0-4.14.0-3.6-3.4-4.53.1
Area under the delay curve0.91.01.60.91.01.01.11.01.01.0-1.1-0.9-1.01.01.0-1.0-1.0-1.1-1.0-1.01.0-1.11.1-0.6-0.6-1.30.8
BMI with tail4.113.117.43.63.53.63.93.63.63.6-3.9-3.6-3.53.53.7-3.8-3.6-3.8-3.6-3.53.6-3.83.8-3.1-3.1-4.23.2
BMI without tail0.00.10.3-0.2-0.4-0.30.0-0.3-0.3-0.3-0.00.20.3-0.3-0.20.00.2-0.10.20.3-0.2-0.20.30.3-0.0-0.50.1
Body weight5.924.727.65.04.84.95.34.94.94.9-5.2-4.9-4.84.85.0-5.2-4.9-5.2-4.9-4.85.0-5.25.2-4.6-4.7-5.04.7
Weight adjusted by age2.12.44.81.61.31.41.51.41.41.4-1.5-1.6-1.51.51.4-1.7-1.5-1.6-1.5-1.61.7-1.61.7-1.8-2.1-0.12.2
Bone surface12.221.523.84.84.94.84.84.84.84.8-4.8-4.8-4.84.84.8-4.6-4.7-4.7-4.7-4.84.6-4.54.5-4.2-4.0-4.63.7
Bone volume9.215.617.74.04.24.14.14.14.14.1-4.1-4.1-4.14.14.1-3.9-4.1-4.0-4.1-4.03.9-3.83.8-3.5-3.3-4.13.0
Breakpoint value in progressive ratio session0.20.20.30.50.40.40.50.40.40.4-0.5-0.5-0.50.50.3-0.5-0.3-0.4-0.3-0.50.5-0.50.5-0.5-0.5-0.10.5
Number of licking bursts0.40.52.2-0.6-1.0-0.8-0.7-0.8-0.8-0.80.70.70.8-0.8-0.80.40.80.50.70.7-0.50.3-0.40.1-0.21.50.4
Context. condit. distance diff. score0.20.30.50.40.40.50.50.50.50.5-0.5-0.2-0.40.40.4-0.6-0.5-0.4-0.5-0.40.5-0.70.6-0.6-0.7-0.60.7
Locomotion velocity, session 11.01.12.2-1.0-1.0-1.1-1.1-1.1-1.1-1.11.10.91.0-1.0-1.11.11.11.01.01.0-1.01.2-1.10.80.81.5-0.8
Locomotion distance, session 12.83.65.3-1.9-1.7-1.9-1.8-1.9-1.9-1.91.81.71.8-1.8-1.82.01.82.01.91.9-2.02.0-2.12.32.31.1-2.3
Locomotion velocity, session 20.20.20.5-0.4-0.2-0.4-0.5-0.4-0.4-0.40.50.20.3-0.3-0.40.60.40.50.40.4-0.50.6-0.70.60.70.3-0.7
Locomotion distance, session 22.23.14.4-1.8-1.5-1.7-1.7-1.7-1.7-1.71.71.61.6-1.6-1.61.91.71.81.71.7-1.81.9-2.02.12.11.2-2.1
Locomotion velocity, session 33.74.35.1-2.1-2.0-2.1-2.1-2.1-2.1-2.12.12.12.0-2.0-2.02.22.12.12.12.1-2.22.1-2.12.32.21.1-2.2
Locomotion distance, session 34.65.06.0-2.2-2.1-2.2-2.4-2.2-2.2-2.22.42.12.1-2.1-2.12.42.22.32.22.2-2.32.4-2.42.32.41.5-2.4
Stereotopy head waving bouts, day 31.41.62.31.31.41.31.11.31.31.3-1.1-1.2-1.21.21.3-1.3-1.3-1.2-1.3-1.31.3-1.21.1-1.5-1.4-0.31.5
Stereotopy head waving duration, day 30.60.71.10.91.00.90.80.90.90.9-0.8-0.8-0.80.80.9-0.8-0.9-0.8-0.9-0.80.8-0.70.6-1.1-0.90.11.0
Locomotion velocity, session 70.10.20.3-0.4-0.4-0.4-0.5-0.4-0.4-0.40.50.40.4-0.4-0.40.50.40.50.40.4-0.40.4-0.20.30.20.5-0.2
Locomotion distance, session 71.51.92.2-1.4-1.5-1.4-1.5-1.4-1.4-1.41.51.41.4-1.4-1.41.41.41.51.41.4-1.41.3-1.21.21.11.3-1.1
Stereotopy head waving bouts, day 71.21.32.51.21.11.11.01.11.11.1-1.0-1.1-1.11.11.0-1.1-1.1-1.2-1.1-1.21.2-1.01.0-1.5-1.5-0.01.6
Stereotopy head waving duration, day 71.31.62.81.31.21.21.11.21.21.2-1.1-1.3-1.31.31.1-1.3-1.2-1.3-1.2-1.31.4-1.21.1-1.6-1.6-0.21.7
Locomotion velocity, session 80.00.00.0-0.00.0-0.00.1-0.0-0.0-0.0-0.10.10.0-0.00.0-0.10.1-0.0-0.00.00.0-0.10.10.0-0.0-0.10.1
Locomotion distance, session 81.21.72.5-1.4-1.2-1.3-1.2-1.3-1.3-1.31.21.41.3-1.3-1.21.41.31.41.21.3-1.41.4-1.51.61.60.4-1.6
Degree of sensitization distance0.50.50.90.70.50.70.70.70.70.7-0.7-0.6-0.60.60.6-0.8-0.7-0.7-0.6-0.60.7-0.80.8-0.8-0.9-0.20.9
Degree of sensitization stereotypy0.30.31.10.50.30.40.30.30.30.3-0.3-0.5-0.50.50.3-0.5-0.3-0.6-0.4-0.50.6-0.50.4-0.9-1.00.51.1
Conditioned locomotion0.20.21.80.30.30.20.00.20.20.2-0.1-0.2-0.30.30.2-0.3-0.3-0.2-0.3-0.40.4-0.20.2-0.8-0.81.30.8
Cocaine response after cond. corrected0.20.22.3-0.10.1-0.00.1-0.0-0.0-0.0-0.1-0.00.0-0.0-0.10.20.10.00.10.1-0.30.1-0.00.80.9-1.5-0.9
Cocaine response after cond. not corrected0.70.82.3-0.8-0.7-0.7-0.7-0.7-0.7-0.70.70.70.7-0.7-0.80.90.80.70.80.8-1.00.9-0.81.41.5-0.6-1.5
Cocaine response before conditioning3.44.26.4-2.0-2.0-2.0-2.2-2.0-2.0-2.02.22.01.9-1.9-2.12.12.02.02.01.9-2.02.4-2.31.61.72.5-1.7
Saline control response0.10.10.20.40.50.50.40.50.50.5-0.3-0.4-0.50.50.4-0.3-0.4-0.4-0.4-0.40.4-0.10.0-0.4-0.3-0.20.2
Bone: connectivity density7.611.915.23.53.73.63.63.63.63.6-3.6-3.6-3.73.73.6-3.4-3.6-3.5-3.6-3.63.3-3.33.3-2.9-2.6-3.92.3
Bone: cortical apparent density0.30.31.3-0.5-0.6-0.5-0.7-0.5-0.5-0.50.70.50.5-0.5-0.60.60.60.70.50.5-0.60.7-0.70.30.31.2-0.2
Bone: cortical area9.814.816.33.93.83.83.93.83.83.8-3.9-4.0-4.04.03.7-3.9-3.8-4.0-3.8-4.03.9-4.04.0-3.6-3.7-3.53.5
Bone: cortical porosity0.80.92.1-0.9-0.7-0.8-1.1-0.8-0.8-0.81.10.90.9-0.9-0.81.00.81.10.80.9-0.81.3-1.30.50.81.5-0.9
Bone: cortical porosity1.21.32.7-1.1-0.9-1.0-1.3-1.0-1.0-1.01.31.21.1-1.1-1.01.21.01.41.01.1-1.01.5-1.50.71.01.6-1.1
Bone: cortical thickness3.65.87.82.42.32.32.62.32.32.3-2.6-2.6-2.52.52.2-2.5-2.2-2.7-2.2-2.52.4-2.82.8-2.1-2.3-2.42.3
Bone: cortical thickness0.10.20.70.30.20.30.50.30.30.3-0.5-0.3-0.40.40.2-0.4-0.2-0.5-0.2-0.40.3-0.60.6-0.1-0.3-0.80.4
Bone: cortical tissue density0.40.51.6-0.6-0.6-0.6-0.8-0.6-0.6-0.60.80.60.6-0.6-0.70.70.70.80.60.6-0.70.8-0.80.30.41.3-0.3
Condit. Reinf. active minus inactive responses0.10.10.3-0.2-0.1-0.2-0.2-0.2-0.2-0.20.20.10.2-0.2-0.20.30.20.20.20.2-0.30.2-0.20.60.6-0.2-0.5
Condit. Reinf. active-inactive response ratio0.30.30.80.60.70.60.60.60.60.6-0.6-0.7-0.60.60.6-0.4-0.6-0.4-0.6-0.50.4-0.50.4-0.1-0.0-0.90.0
Condit. Reinf. active responses0.60.71.1-0.8-0.7-0.8-0.7-0.8-0.8-0.80.70.80.9-0.9-0.80.80.80.80.80.9-0.90.7-0.81.11.00.6-0.9
Condit. Reinf. inactive responses2.83.44.0-1.9-1.9-1.9-1.8-1.9-1.9-1.91.82.01.9-1.9-1.91.81.81.81.91.9-1.81.8-1.81.61.62.0-1.5
Incentive salience index mean0.00.00.10.20.20.10.20.10.10.1-0.3-0.2-0.10.10.2-0.2-0.1-0.2-0.1-0.10.1-0.40.30.1-0.0-0.30.1
Condit. Reinf. lever presses0.10.20.50.30.30.30.50.30.30.3-0.5-0.3-0.30.30.4-0.5-0.3-0.5-0.3-0.40.4-0.70.7-0.1-0.4-0.40.6
Condit. Reinf. active minus inactive responses0.00.00.2-0.0-0.1-0.1-0.2-0.1-0.1-0.10.2-0.00.1-0.1-0.10.20.10.20.00.1-0.10.3-0.3-0.10.10.4-0.0
Condit. Reinf. active-inactive response ratio0.30.30.4-0.6-0.6-0.6-0.6-0.6-0.6-0.60.60.40.5-0.5-0.60.60.60.50.60.5-0.60.7-0.60.60.60.5-0.5
Condit. Reinf. active responses0.20.20.4-0.4-0.5-0.4-0.6-0.4-0.4-0.40.60.50.5-0.5-0.40.50.40.60.40.5-0.50.6-0.60.20.40.7-0.4
Condit. Reinf. inactive responses0.60.71.4-0.9-0.9-0.8-1.0-0.8-0.8-0.81.01.00.9-0.9-0.80.90.80.90.80.9-0.81.0-0.90.40.51.2-0.5
Condit. Reinf. lever presses0.00.00.00.0-0.00.1-0.00.10.10.10.00.00.0-0.0-0.00.0-0.00.1-0.00.0-0.00.1-0.1-0.10.1-0.00.1
Condit. Reinf. lever reinforcers received0.50.70.9-0.8-0.9-0.8-0.9-0.8-0.8-0.80.90.80.8-0.8-0.80.90.80.90.80.8-0.80.9-0.90.60.70.9-0.7
Conditioned reinforcement - actives1.61.62.1-1.3-1.4-1.4-1.3-1.5-1.5-1.51.31.21.2-1.2-1.11.21.31.21.21.2-1.21.1-1.11.21.01.2-1.0
Conditioned reinforcement - inactives1.92.23.1-1.6-1.5-1.7-1.4-1.7-1.7-1.71.41.41.4-1.4-1.31.51.41.41.41.4-1.41.3-1.31.71.50.8-1.4
Conditioned locomotion0.40.51.3-0.7-0.8-0.9-0.7-0.9-0.9-0.90.70.60.6-0.6-0.50.60.60.60.50.6-0.50.7-0.70.40.21.1-0.2
Patch foraging indifference point 0 sec2.23.64.0-2.0-2.0-2.0-1.9-2.0-2.0-2.01.91.91.9-1.9-2.01.92.01.82.01.9-1.91.9-1.91.91.81.3-1.8
Patch foraging indifference point AUC0.20.20.6-0.4-0.5-0.5-0.5-0.5-0.5-0.50.60.20.3-0.3-0.40.50.50.30.50.3-0.40.6-0.60.20.20.7-0.2
Delay disc. indifference point, 0s delay1.31.41.81.31.21.21.11.11.11.1-1.1-1.4-1.31.31.3-1.2-1.2-1.3-1.2-1.31.2-1.11.1-1.2-1.1-0.51.2
Delay disc. indifference point, 16s delay0.90.91.30.90.90.91.00.80.80.8-1.0-1.0-0.90.90.9-1.0-1.0-1.1-0.9-1.01.0-1.11.1-0.9-1.1-0.81.1
Delay disc. indifference point, 2s delay1.31.51.81.31.31.31.21.41.41.4-1.2-1.1-1.21.21.2-1.2-1.2-1.2-1.3-1.21.2-1.21.2-1.3-1.1-0.81.2
Delay disc. indifference point, 24s delay1.31.31.61.11.11.11.21.11.11.1-1.2-1.1-1.21.21.2-1.2-1.1-1.2-1.1-1.21.2-1.11.2-1.1-1.1-1.01.2
Delay disc. indifference point, 4s delay0.30.31.40.40.60.60.60.60.60.6-0.6-0.3-0.40.40.4-0.4-0.5-0.5-0.5-0.40.3-0.60.50.00.1-1.20.1
Delay disc. indifference point, 8s delay2.62.74.11.61.61.61.81.51.51.5-1.8-1.6-1.71.71.6-1.6-1.6-1.8-1.6-1.71.6-1.81.8-1.1-1.2-2.01.4
Indifference point function ln k3.75.26.12.32.42.42.32.42.42.4-2.3-2.3-2.32.32.3-2.3-2.5-2.2-2.4-2.32.3-2.12.1-2.2-2.1-1.72.1
Indifference point function log k3.75.26.12.32.42.42.32.42.42.4-2.3-2.3-2.32.32.3-2.3-2.5-2.2-2.4-2.32.3-2.12.1-2.2-2.1-1.72.1
Patch foraging total patch changes 0 sec2.13.43.9-1.9-2.0-1.9-1.9-1.9-1.9-1.91.91.91.9-1.9-2.01.82.01.82.01.9-1.91.9-1.81.71.71.4-1.7
Patch foraging total patch changes 12 sec2.02.63.5-1.7-1.9-1.8-1.7-1.8-1.8-1.81.71.51.6-1.6-1.71.51.81.41.81.5-1.51.4-1.41.41.11.7-1.0
Patch foraging total patch changes 18 sec4.05.26.6-2.3-2.3-2.3-2.4-2.3-2.3-2.32.52.22.2-2.2-2.32.32.32.22.32.2-2.22.6-2.51.81.92.5-1.9
Patch foraging total patch changes 24 sec2.02.44.2-1.6-1.7-1.6-1.7-1.6-1.6-1.61.71.61.5-1.5-1.81.51.71.41.71.5-1.51.4-1.41.00.92.1-0.9
Patch foraging total patch changes 6 sec2.33.43.9-1.9-2.0-2.0-1.9-2.0-2.0-2.01.91.81.8-1.8-1.91.92.01.71.91.8-1.91.9-1.91.81.71.3-1.7
Patch foraging time to switch 0 sec2.33.54.3-1.9-1.9-1.8-1.9-1.8-1.8-1.81.92.12.1-2.1-2.01.91.92.01.92.0-1.91.7-1.81.71.61.9-1.6
Patch foraging water rate 0 sec2.94.75.62.22.22.22.22.12.12.1-2.2-2.3-2.32.32.1-2.2-2.1-2.4-2.1-2.32.2-2.22.2-2.1-2.1-1.82.1
Patch foraging water rate 12 sec3.85.86.62.52.62.52.42.52.52.5-2.4-2.4-2.52.52.6-2.4-2.6-2.4-2.5-2.52.4-2.22.2-2.5-2.3-1.92.2
Patch foraging water rate 18 sec0.30.40.60.50.50.50.60.50.50.5-0.6-0.4-0.50.50.5-0.6-0.5-0.6-0.5-0.60.6-0.80.8-0.6-0.7-0.80.7
Patch foraging water rate 24 sec3.24.56.42.22.12.22.02.22.22.2-2.0-2.0-2.12.12.0-2.2-2.1-2.1-2.1-2.12.2-1.91.9-2.5-2.5-0.92.4
Patch foraging water rate 6 sec3.85.66.02.42.42.42.32.42.42.4-2.3-2.3-2.42.42.4-2.4-2.5-2.4-2.4-2.42.4-2.42.4-2.4-2.4-1.72.4
Seeking ratio, delayed vs. immediate footshock0.40.42.50.50.60.50.70.50.50.5-0.7-0.7-0.60.60.7-0.5-0.6-0.6-0.6-0.50.4-0.70.70.00.0-1.6-0.0
Distance traveled before self-admin1.11.22.8-1.1-1.1-1.1-1.2-1.1-1.1-1.11.21.21.2-1.2-1.11.01.11.21.11.2-1.01.0-1.00.70.61.7-0.6
Distance traveled after self-admin0.20.20.4-0.5-0.3-0.4-0.4-0.4-0.4-0.40.40.40.5-0.5-0.30.40.30.50.30.5-0.50.5-0.60.40.50.5-0.6
Extensor digitorum longus weight3.915.220.54.03.43.74.13.63.63.6-4.1-4.1-3.83.83.5-4.2-3.5-4.1-3.5-3.84.0-4.54.5-3.8-4.3-3.34.3
Bone: elastic displacement4.55.16.0-2.3-2.2-2.2-2.3-2.2-2.2-2.22.32.42.3-2.3-2.32.32.22.42.22.3-2.32.4-2.42.02.12.3-2.1
Bone: elastic work0.00.00.20.10.20.2-0.10.20.20.20.00.10.0-0.00.10.0-0.10.2-0.10.00.00.2-0.2-0.10.00.4-0.1
Bone: endosteal estimation7.816.918.74.34.24.24.14.24.24.2-4.0-4.2-4.24.24.3-4.1-4.3-4.1-4.3-4.24.2-3.83.9-4.3-4.1-2.93.9
Bone: endosteal perimeter6.814.115.13.93.63.73.83.73.73.7-3.8-3.9-3.93.93.7-3.8-3.8-3.8-3.8-3.93.8-3.83.8-3.8-3.8-2.93.8
Epididymis fat weight0.10.31.10.60.60.70.60.70.70.7-0.6-0.4-0.40.40.7-0.5-0.7-0.5-0.7-0.40.4-0.60.6-0.4-0.2-1.00.2
Delta time in closed arm before/after self-admin0.30.32.70.50.60.50.60.50.50.5-0.6-0.6-0.60.60.5-0.4-0.4-0.5-0.4-0.50.4-0.50.40.00.2-1.6-0.1
Delta time in open arm before/after self-admin4.34.16.4-2.1-2.1-2.1-2.1-2.1-2.1-2.12.12.12.1-2.1-2.02.02.02.12.02.1-2.02.0-1.91.71.52.5-1.6
Diff in mean of infusions in LGA sessions1.51.72.51.31.31.31.41.31.31.3-1.4-1.2-1.31.31.3-1.3-1.3-1.2-1.3-1.21.2-1.51.6-1.0-0.9-1.40.9
Delay discount exponential model param0.80.81.5-0.9-0.9-0.9-1.1-0.9-0.9-0.91.10.80.9-0.9-0.90.90.91.00.90.9-0.91.1-1.10.50.61.2-0.8
Extinction: sum of active levers before priming0.40.40.60.70.60.70.60.70.70.7-0.6-0.7-0.60.60.5-0.7-0.6-0.6-0.6-0.70.7-0.70.7-0.8-0.80.00.6
Active lever presses in extinction session 60.40.40.50.60.70.60.70.60.60.6-0.7-0.7-0.70.70.6-0.7-0.6-0.7-0.6-0.70.7-0.70.6-0.5-0.5-0.60.5
Bone: final force10.116.317.84.14.24.14.24.14.14.1-4.2-4.2-4.14.14.1-4.1-4.1-4.1-4.1-4.14.0-4.14.0-3.6-3.5-3.93.4
Bone: final moment10.617.219.14.34.44.34.34.34.34.3-4.3-4.3-4.34.34.3-4.2-4.2-4.2-4.2-4.24.1-4.14.1-3.7-3.5-4.03.3
Food consumed during 24 hour testing period1.82.24.31.51.61.51.61.51.51.5-1.6-1.6-1.61.61.6-1.4-1.5-1.5-1.5-1.61.4-1.31.2-1.0-0.9-2.11.0
Glucose0.10.10.40.2-0.00.10.30.10.10.1-0.3-0.1-0.10.10.1-0.4-0.1-0.3-0.1-0.10.3-0.50.6-0.4-0.6-0.20.7
Heart weight0.00.10.40.20.30.20.30.20.20.2-0.3-0.3-0.20.20.3-0.2-0.3-0.2-0.2-0.20.1-0.20.20.00.1-0.7-0.2
Delay discount hyperbolic model param0.80.81.4-0.9-1.0-0.9-1.0-0.9-0.9-0.91.00.70.9-0.9-0.90.90.91.00.90.9-0.81.0-1.00.60.61.2-0.7
Intermittent access intake day 1-15 change1.41.42.1-1.2-1.3-1.3-1.1-1.3-1.3-1.31.11.21.2-1.2-1.11.21.21.21.11.2-1.20.8-0.81.41.30.2-1.1
Intermittent access intake escalation1.01.01.7-1.1-1.1-1.1-0.9-1.1-1.1-1.10.91.01.0-1.0-0.91.01.01.00.91.0-1.00.6-0.71.31.2-0.1-1.0
Intermittent access intake escalation 21.51.52.4-1.3-1.4-1.4-1.2-1.4-1.4-1.41.21.31.3-1.3-1.21.31.21.31.21.3-1.30.8-0.81.51.40.2-1.2
Intermitt. access day 1 inactive lever presses3.03.37.4-1.7-1.8-1.6-1.9-1.6-1.6-1.61.91.91.9-1.9-1.91.71.91.91.91.8-1.72.0-2.01.01.22.7-1.3
Intermitt. access day 15 inactive lever presses1.31.41.8-1.2-1.2-1.2-1.2-1.2-1.2-1.21.21.31.3-1.3-1.11.21.11.31.11.3-1.21.3-1.30.90.91.3-1.0
Intermitt. access escalation Index0.30.30.5-0.4-0.6-0.3-0.5-0.3-0.3-0.30.50.70.7-0.7-0.70.40.50.60.60.6-0.50.5-0.50.20.20.5-0.1
Intermittent access day 1 total infusions1.21.41.7-1.2-1.2-1.3-1.1-1.3-1.3-1.31.11.11.1-1.1-1.11.21.11.11.11.1-1.21.2-1.21.31.20.7-1.1
Intermittent access day 15 total infusions2.62.93.7-1.8-1.9-1.9-1.7-1.9-1.9-1.91.71.71.7-1.7-1.71.71.71.71.71.7-1.71.4-1.51.91.60.9-1.4
Intermittent access terminal intake (last 3 days)2.83.03.7-1.9-1.9-1.9-1.8-1.9-1.9-1.91.81.71.7-1.7-1.71.81.61.81.71.7-1.71.6-1.61.91.71.0-1.6
Intermittent access total infusions2.62.93.5-1.8-1.8-1.9-1.7-1.9-1.9-1.91.71.71.7-1.7-1.71.71.61.71.71.7-1.71.6-1.61.81.51.1-1.5
Intermittent access day 1 locomotion1.01.02.5-1.0-1.1-1.0-1.1-1.0-1.0-1.01.11.01.0-1.0-1.10.91.01.01.01.0-0.91.1-1.10.50.51.6-0.5
Intermittent access day 15 total locomotion1.61.73.2-1.4-1.5-1.6-1.4-1.6-1.6-1.61.41.31.3-1.3-1.31.21.21.31.21.2-1.11.1-1.10.90.61.8-0.6
Intermittent access total locomotion3.43.87.6-2.0-2.2-2.1-2.1-2.2-2.2-2.22.11.91.9-1.9-2.01.91.92.01.91.9-1.81.9-1.91.31.02.8-1.1
Intermittent access standard deviation0.50.50.9-0.8-0.8-0.8-0.7-0.8-0.8-0.80.70.80.8-0.8-0.70.70.80.70.80.8-0.80.4-0.50.90.80.2-0.7
Left kidney weight0.41.25.80.91.21.01.21.01.01.0-1.2-1.1-1.01.01.2-0.9-1.1-1.1-1.1-1.00.9-1.11.1-0.2-0.1-2.40.1
Right kidney weight2.77.68.92.82.72.62.82.62.62.6-2.8-2.8-2.72.73.0-2.8-3.0-2.9-2.9-2.72.8-2.92.9-2.5-2.6-2.62.5
Cocaine induced anxiety1.11.31.81.11.01.11.11.11.11.1-1.1-1.1-1.11.11.1-1.2-1.1-1.1-1.1-1.11.3-1.21.2-1.2-1.4-0.71.3
Post-drug Anxiety4.95.56.02.42.32.42.42.42.42.4-2.4-2.3-2.32.32.5-2.4-2.4-2.3-2.4-2.32.4-2.22.2-2.5-2.5-1.82.3
Baseline Anxiety0.91.01.21.01.01.01.11.01.01.0-1.1-1.0-1.01.01.1-1.0-1.0-1.1-1.0-1.00.9-1.01.0-0.8-0.8-1.10.8
Tail length0.10.30.4-0.6-0.6-0.6-0.6-0.6-0.6-0.60.60.60.6-0.6-0.50.50.40.40.50.6-0.50.5-0.40.30.20.5-0.3
Length with tail1.96.97.62.72.62.72.72.72.72.7-2.7-2.6-2.62.62.8-2.7-2.7-2.7-2.7-2.62.6-2.62.6-2.6-2.5-2.32.4
Length without tail7.316.118.14.14.14.14.34.14.14.1-4.2-4.1-4.04.04.1-4.1-4.0-4.1-4.1-4.04.0-4.14.0-3.5-3.4-4.33.4
Times rat made contact with spout0.10.10.5-0.4-0.4-0.4-0.2-0.4-0.4-0.40.20.30.5-0.5-0.40.30.40.20.40.5-0.40.0-0.20.70.5-0.4-0.4
Lifetime Intake2.42.73.6-1.8-1.8-1.9-1.6-1.9-1.9-1.91.61.61.6-1.6-1.61.61.61.61.61.6-1.61.4-1.41.81.41.0-1.4
Liver weight, left1.82.93.91.71.61.71.81.61.61.6-1.8-1.7-1.71.71.7-1.8-1.6-1.7-1.6-1.71.7-1.92.0-1.6-1.7-1.91.6
Liver weight, right1.52.43.21.61.41.61.61.61.61.6-1.6-1.5-1.51.51.5-1.6-1.6-1.5-1.5-1.51.5-1.71.8-1.5-1.5-1.61.5
Locomotor activity1.01.52.6-1.3-1.4-1.4-1.4-1.4-1.4-1.41.41.31.2-1.2-1.31.21.31.21.31.1-1.20.9-0.91.10.71.6-0.7
Locomotor testing distance2.74.55.4-2.2-2.2-2.2-2.3-2.2-2.2-2.22.32.22.1-2.1-2.22.22.22.12.22.1-2.21.9-1.91.91.72.3-1.6
Locomotor testing rearing2.33.55.6-1.9-2.1-1.9-2.0-1.9-1.9-1.92.02.02.0-2.0-2.01.81.91.91.91.9-1.91.8-1.81.31.22.4-1.1
Locomotion in novel chamber0.60.70.90.90.80.80.80.80.80.8-0.8-0.9-0.80.80.8-0.9-0.8-0.9-0.8-0.80.8-0.80.8-0.9-0.8-0.41.0
Locomotion in novel chamber post-restriction0.00.00.10.20.20.20.10.20.20.2-0.1-0.1-0.10.10.2-0.2-0.2-0.1-0.2-0.10.2-0.10.2-0.3-0.30.10.2
Fecal boli incidents, locomotor time 12.32.66.1-1.7-1.5-1.6-1.2-1.6-1.6-1.61.31.61.7-1.7-1.51.61.51.41.61.7-1.81.0-1.12.52.2-0.4-2.0
Change in fecal boli incidents, locomotor task1.51.41.91.21.31.21.11.21.21.2-1.1-1.0-1.21.21.4-1.2-1.3-1.1-1.3-1.21.3-0.91.0-1.4-1.4-0.41.2
Time >=10cm from walls, locomotor time 10.20.20.90.30.40.40.50.40.40.4-0.5-0.3-0.40.40.4-0.4-0.4-0.4-0.4-0.30.3-0.50.6-0.0-0.0-0.90.1
Bouts of movement, locomotor time 10.00.00.3-0.00.1-0.10.1-0.1-0.1-0.1-0.2-0.00.0-0.00.2-0.0-0.2-0.0-0.10.10.0-0.30.30.40.2-0.6-0.2
Total resting periods, locomotor time 10.20.30.8-0.6-0.4-0.6-0.3-0.6-0.6-0.60.30.50.5-0.5-0.40.50.30.50.50.6-0.50.3-0.20.90.7-0.2-0.7
Rest time, locomotor task time 10.40.41.0-0.7-0.7-0.7-0.5-0.7-0.7-0.70.50.70.8-0.8-0.50.60.60.60.60.8-0.70.5-0.51.00.8-0.0-0.7
Distance moved, locomotor task time 10.00.00.30.20.20.30.00.30.30.3-0.0-0.2-0.20.20.1-0.1-0.2-0.1-0.2-0.20.1-0.0-0.1-0.5-0.20.30.2
Vertical activity count, locomotor time 11.41.53.21.21.31.21.31.21.21.2-1.3-1.3-1.31.31.2-1.1-1.2-1.2-1.2-1.31.2-1.31.2-0.9-0.7-1.80.8
Time >=10cm from walls, locomotor time 20.50.50.7-0.8-0.7-0.8-0.8-0.8-0.8-0.80.80.80.8-0.8-0.70.80.70.70.70.7-0.70.5-0.40.90.60.7-0.6
Bouts of movement, locomotor time 22.52.73.41.71.61.61.61.61.61.6-1.6-1.6-1.61.61.7-1.7-1.8-1.7-1.7-1.71.7-1.71.8-1.8-1.8-0.71.9
Total resting periods, locomotor time 22.93.13.91.81.71.71.71.71.71.7-1.7-1.7-1.71.71.8-1.8-1.9-1.8-1.8-1.71.8-1.81.8-2.0-1.9-0.81.9
Rest time, locomotor task time 20.00.00.40.10.00.10.20.10.10.1-0.20.10.1-0.10.1-0.2-0.1-0.1-0.10.10.0-0.20.40.10.1-0.60.0
Distance moved, locomotor task time 20.10.10.4-0.2-0.2-0.2-0.4-0.2-0.2-0.20.30.10.1-0.1-0.30.30.20.30.20.2-0.20.4-0.50.10.30.6-0.2
Vertical activity count, locomotor time 20.00.00.10.20.20.10.10.10.10.1-0.1-0.4-0.40.40.2-0.1-0.2-0.2-0.2-0.40.3-0.30.2-0.2-0.2-0.10.3
Light reinforcement 12.64.87.8-2.2-2.4-2.3-2.4-2.3-2.3-2.32.42.22.2-2.2-2.32.22.32.22.32.2-2.02.1-2.01.61.42.8-1.4
Light reinforcement 20.81.11.4-1.1-1.2-1.2-1.1-1.2-1.2-1.21.11.11.1-1.1-1.11.11.11.01.11.1-0.90.8-0.81.10.70.8-0.7
Bone: marrow area7.616.518.34.24.14.24.04.24.24.2-4.0-4.1-4.24.24.2-4.1-4.3-4.0-4.2-4.24.1-3.83.8-4.3-4.1-2.83.9
Bone: maximum diameter3.97.18.22.72.52.52.72.52.52.5-2.7-2.8-2.82.82.6-2.8-2.6-2.8-2.5-2.82.7-2.92.9-2.7-2.8-2.22.7
Bone: maximum force14.224.526.95.15.25.25.15.15.15.1-5.1-5.0-5.05.05.1-5.0-5.1-5.0-5.1-5.05.0-4.84.8-4.8-4.5-4.24.3
Bone: maximum moment14.725.328.65.25.45.35.15.35.35.3-5.1-5.1-5.15.15.2-5.0-5.2-5.0-5.2-5.15.0-4.84.8-4.8-4.5-4.34.2
Mean time between licks in bursts0.10.10.4-0.3-0.0-0.1-0.4-0.1-0.1-0.10.30.40.2-0.2-0.10.40.20.40.10.2-0.30.5-0.50.20.40.7-0.4
Mean num. licks in bursts0.20.22.1-0.00.40.10.20.10.10.1-0.2-0.1-0.20.20.20.1-0.1-0.0-0.1-0.0-0.10.1-0.20.71.0-1.4-1.0
Cd content in liver0.60.60.9-0.8-1.0-0.9-0.8-0.9-0.9-0.90.80.80.8-0.8-0.90.80.90.80.90.8-0.80.6-0.60.90.60.5-0.5
Co content in liver0.60.71.4-0.9-1.2-1.1-0.6-1.1-1.1-1.10.60.80.9-0.9-1.00.61.00.51.10.8-0.70.1-0.11.00.30.4-0.0
Cu content in liver0.60.71.60.70.60.71.00.70.70.7-1.0-0.4-0.50.50.8-1.0-0.7-0.7-0.7-0.60.8-1.31.2-0.6-1.0-1.11.1
Fe content in liver0.40.51.0-0.8-1.0-0.8-0.5-0.8-0.8-0.80.50.90.8-0.8-0.80.50.80.60.80.8-0.70.2-0.30.70.30.3-0.3
K content in liver0.20.21.40.30.30.30.60.30.30.3-0.6-0.1-0.10.10.4-0.5-0.4-0.4-0.4-0.20.4-0.80.7-0.1-0.3-1.20.5
Mg content in liver0.00.00.3-0.1-0.1-0.1-0.0-0.1-0.1-0.10.00.10.1-0.1-0.00.10.1-0.00.10.1-0.1-0.10.00.30.2-0.5-0.1
Mn content in liver0.10.10.30.30.40.40.20.40.40.4-0.2-0.2-0.20.20.4-0.2-0.4-0.1-0.4-0.20.2-0.10.1-0.6-0.30.00.2
Na content in liver0.10.10.3-0.3-0.4-0.3-0.2-0.3-0.3-0.30.20.40.4-0.4-0.30.10.30.30.30.4-0.2-0.00.00.2-0.10.50.2
Rb content in liver0.40.40.8-0.7-0.9-0.8-0.6-0.8-0.8-0.80.60.70.8-0.8-0.80.60.80.60.80.7-0.60.3-0.30.60.30.5-0.1
Se content in liver0.60.71.0-0.9-0.9-0.9-0.8-0.9-0.9-0.90.81.01.0-1.0-0.80.80.80.80.81.0-0.90.7-0.71.00.9-0.1-0.8
Sr content in liver0.50.40.70.70.50.50.60.50.50.5-0.6-0.8-0.90.90.5-0.6-0.5-0.8-0.5-0.90.6-0.80.8-0.6-0.8-0.60.8
Zn content in liver1.82.02.9-1.5-1.7-1.6-1.4-1.6-1.6-1.61.41.41.5-1.5-1.61.31.61.31.61.4-1.41.1-1.11.20.81.7-0.8
Bone: minimum diameter9.217.218.94.34.14.24.14.14.14.1-4.1-4.3-4.34.34.1-4.2-4.2-4.2-4.2-4.34.2-4.14.1-4.3-4.2-2.94.1
Time in familiar zone, hab. session 10.40.40.7-0.6-0.5-0.5-0.5-0.5-0.5-0.50.50.60.6-0.6-0.50.60.60.60.60.6-0.70.6-0.60.80.80.2-0.9
Time in novel zone, hab. session 10.40.41.10.60.40.50.40.50.50.5-0.4-0.5-0.50.50.5-0.6-0.5-0.5-0.5-0.60.7-0.50.6-1.0-1.00.31.0
Total zone transitions, hab. session 10.30.50.6-0.7-0.7-0.7-0.7-0.7-0.7-0.70.70.70.6-0.6-0.70.70.70.70.70.6-0.60.6-0.70.60.50.8-0.5
Total locomotion distance, hab. session 10.00.00.10.10.30.20.10.20.20.2-0.1-0.1-0.20.20.3-0.0-0.30.0-0.2-0.10.10.0-0.1-0.00.1-0.2-0.2
Locomotion velocity, hab. session 10.00.10.20.20.40.30.20.30.30.3-0.2-0.2-0.30.30.3-0.1-0.4-0.1-0.3-0.30.2-0.1-0.0-0.1-0.0-0.1-0.0
Time in familiar zone, hab. session 20.30.30.70.50.70.60.60.60.60.6-0.6-0.5-0.60.60.6-0.5-0.5-0.5-0.6-0.50.4-0.40.4-0.2-0.0-0.9-0.0
Time in novel zone, hab. session 20.30.31.8-0.4-0.6-0.5-0.6-0.5-0.5-0.50.60.50.5-0.5-0.60.40.50.50.50.5-0.30.4-0.4-0.2-0.31.40.3
Total zone transitions, hab. session 20.30.40.9-0.6-0.5-0.6-0.5-0.6-0.6-0.60.50.50.5-0.5-0.50.70.60.60.60.5-0.70.5-0.61.00.90.1-0.9
Total locomotion distance, hab. session 20.10.10.5-0.20.0-0.1-0.3-0.1-0.1-0.10.30.30.2-0.2-0.10.40.10.40.10.3-0.40.4-0.40.50.6-0.1-0.7
Locomotion velocity, hab. session 20.00.10.3-0.10.20.0-0.10.10.10.10.10.10.1-0.10.10.2-0.10.2-0.00.1-0.20.2-0.20.40.5-0.4-0.6
Novel to familiar place preference ratio1.71.72.91.41.11.31.31.31.31.3-1.3-1.3-1.11.11.2-1.4-1.3-1.3-1.3-1.21.4-1.31.4-1.6-1.7-0.61.7
Novelty place preference1.21.22.41.20.91.11.01.11.11.1-1.1-1.1-1.01.01.0-1.2-1.1-1.1-1.0-1.01.2-1.11.1-1.5-1.5-0.41.5
Time in novel zone, NPP test1.01.02.21.10.81.00.91.01.01.0-0.9-0.9-0.90.90.9-1.1-1.0-1.0-0.9-0.91.1-0.91.0-1.5-1.5-0.21.5
Total zone transitions, NPP test1.31.83.2-1.4-1.2-1.4-1.2-1.4-1.4-1.41.21.21.3-1.3-1.31.41.41.31.41.3-1.41.2-1.31.81.60.5-1.5
Total locomotion distance, NPP test1.52.13.1-1.4-1.2-1.3-1.5-1.3-1.3-1.31.51.31.4-1.4-1.31.61.31.51.31.4-1.51.5-1.61.71.71.0-1.7
Locomotion velocity, NPP test0.81.12.0-1.0-0.8-1.0-1.0-1.0-1.0-1.01.00.91.0-1.0-0.91.20.91.11.01.1-1.21.1-1.21.41.40.5-1.4
Intraocular pressure7.410.311.3-3.3-3.2-3.3-3.4-3.3-3.3-3.33.43.23.2-3.2-3.23.33.23.23.23.2-3.23.2-3.32.92.83.3-2.9
Delta distance traveled before/after self-admin0.10.10.80.20.40.30.30.30.30.3-0.3-0.3-0.30.30.4-0.2-0.4-0.3-0.4-0.20.1-0.20.10.00.2-0.9-0.3
Delta ambulatory time before/after self-admin0.00.00.40.00.10.10.10.00.00.0-0.1-0.1-0.10.10.2-0.0-0.2-0.1-0.1-0.1-0.0-0.10.00.10.2-0.6-0.2
Parametrial fat weight2.24.25.2-2.1-2.1-2.1-2.0-2.1-2.1-2.12.02.12.2-2.2-2.12.12.12.02.12.2-2.11.9-2.02.32.11.2-2.1
Pavlov. Cond. lever latency0.10.10.20.20.40.40.10.40.40.4-0.2-0.1-0.30.30.3-0.2-0.4-0.0-0.4-0.30.30.2-0.2-0.5-0.10.3-0.0
Pavlov. Cond. magazine entry latency0.00.00.60.00.10.00.10.00.00.0-0.1-0.10.0-0.00.10.0-0.1-0.0-0.10.0-0.0-0.0-0.00.30.4-0.8-0.3
Pavlov. Cond. change in total contacts0.00.00.30.1-0.00.00.20.00.00.0-0.2-0.2-0.10.10.1-0.2-0.0-0.3-0.1-0.10.1-0.40.40.0-0.2-0.50.3
Pavlov. Cond. index score0.10.10.40.1-0.10.00.20.00.00.0-0.2-0.2-0.00.00.1-0.2-0.0-0.3-0.0-0.10.2-0.60.60.1-0.3-0.60.4
Pavlov. Cond. latency score0.00.10.50.1-0.1-0.00.2-0.0-0.0-0.0-0.2-0.20.0-0.00.0-0.10.0-0.20.00.00.1-0.50.50.2-0.2-0.70.3
Pavlov. Cond. lever contacts0.40.51.0-0.7-1.0-0.9-0.6-0.9-0.9-0.90.60.60.8-0.8-0.80.60.90.50.90.8-0.70.3-0.30.90.60.0-0.4
Pavlov. Cond. magazine entry number0.00.00.20.20.30.20.10.20.20.2-0.1-0.1-0.20.20.1-0.1-0.2-0.1-0.2-0.20.20.1-0.0-0.4-0.20.50.1
Pavlov. Cond. intertrial magazine entries0.30.40.9-0.6-0.4-0.6-0.6-0.6-0.6-0.60.60.50.5-0.5-0.60.70.60.60.60.5-0.70.7-0.60.80.90.4-1.0
Pavlov. Cond. lever-magazine prob. diff.0.20.31.00.40.20.30.60.30.30.3-0.6-0.5-0.30.30.4-0.5-0.3-0.6-0.3-0.40.5-0.90.9-0.2-0.5-1.00.6
Pavlov. Cond. response bias0.10.10.4-0.3-0.4-0.3-0.2-0.3-0.3-0.30.20.10.3-0.3-0.20.30.30.20.30.3-0.30.0-0.10.60.5-0.6-0.4
Pavlov. Cond. lever latency0.00.00.10.20.20.20.10.10.10.1-0.1-0.2-0.20.20.2-0.1-0.2-0.1-0.2-0.20.10.00.0-0.1-0.0-0.0-0.1
Pavlov. Cond. magazine entry latency1.11.21.51.21.21.21.11.11.11.1-1.1-1.2-1.21.21.1-1.1-1.1-1.1-1.1-1.21.1-0.90.9-1.2-1.0-0.81.0
Pavlov. Cond. change in total contacts1.31.83.01.31.11.31.51.31.31.3-1.5-1.2-1.11.11.2-1.4-1.2-1.5-1.2-1.21.3-1.61.6-1.1-1.2-1.71.4
Pavlov. Cond. index score0.40.60.70.70.70.80.80.80.80.8-0.8-0.7-0.70.70.7-0.8-0.7-0.8-0.7-0.70.8-0.80.8-0.8-0.8-0.70.8
Pavlov. Cond. latency score0.50.60.80.80.80.80.90.80.80.8-0.9-0.8-0.80.80.7-0.8-0.7-0.8-0.7-0.80.8-0.80.9-0.7-0.7-0.80.8
Pavlov. Cond. lever contacts0.10.20.3-0.4-0.5-0.4-0.4-0.4-0.4-0.40.40.50.5-0.5-0.50.40.50.40.50.5-0.40.3-0.30.40.40.1-0.3
Pavlov. Cond. magazine entry number2.22.73.1-1.7-1.6-1.6-1.6-1.6-1.6-1.61.61.61.7-1.7-1.51.71.61.71.61.7-1.71.7-1.71.71.71.1-1.8
Pavlov. Cond. intertrial magazine entries5.06.57.1-2.6-2.6-2.6-2.6-2.6-2.6-2.62.62.52.6-2.6-2.62.62.62.52.62.6-2.72.5-2.52.62.51.9-2.4
Pavlov. Cond. lever-magazine prob. diff.0.81.11.41.01.01.01.11.01.01.0-1.1-0.9-1.01.00.9-1.1-0.9-1.1-1.0-1.01.1-1.11.1-1.1-1.1-0.81.2
Pavlov. Cond. response bias0.00.00.0-0.1-0.2-0.1-0.0-0.1-0.1-0.10.00.20.1-0.1-0.20.00.10.10.10.1-0.1-0.0-0.00.0-0.0-0.00.1
Time in closed arm before self-admin1.51.72.91.31.21.21.21.21.21.2-1.2-1.2-1.31.31.3-1.4-1.3-1.3-1.3-1.31.4-1.11.3-1.6-1.7-0.61.7
Time in closed arm after self-admin0.70.71.10.90.90.90.90.90.90.9-0.9-0.9-0.90.90.9-0.8-0.9-0.8-0.9-0.90.9-0.70.7-0.8-0.7-1.00.7
Time in open arm before self-admin0.70.71.10.90.80.90.90.90.90.9-0.9-0.8-0.80.80.8-0.8-0.8-0.8-0.8-0.80.8-1.01.0-0.8-0.6-1.00.8
Time in open arm after self-admin0.30.41.4-0.6-0.6-0.6-0.6-0.6-0.6-0.60.60.60.7-0.7-0.60.50.60.60.60.7-0.50.5-0.50.30.31.2-0.3
Bone: periosteal estimation12.024.926.95.15.05.05.05.05.05.0-5.0-5.2-5.25.25.0-5.1-5.1-5.1-5.0-5.25.1-5.05.0-4.9-4.9-4.14.6
Bone: periosteal perimeter10.317.118.54.24.14.14.34.14.14.1-4.2-4.3-4.34.34.1-4.2-4.1-4.3-4.1-4.24.1-4.24.2-3.9-3.8-3.93.7
Bone: post-yield work8.411.514.03.53.53.53.33.53.53.5-3.3-3.5-3.53.53.4-3.4-3.5-3.3-3.5-3.53.5-3.13.1-3.7-3.5-1.93.3
Progressive ratio test 1 active lever presses4.44.65.6-2.3-2.3-2.4-2.2-2.4-2.4-2.42.22.12.1-2.1-2.32.12.12.12.22.1-2.12.0-2.02.01.62.1-1.6
Progressive ratio test 1 breakpoint4.04.25.3-2.2-2.2-2.3-2.1-2.3-2.3-2.32.12.02.0-2.0-2.22.02.02.02.12.0-2.01.9-1.91.91.52.0-1.5
Progressive ratio test 1 inactive lever presses3.74.14.7-2.1-2.2-2.2-2.1-2.2-2.2-2.22.12.02.0-2.0-2.12.02.12.02.02.0-1.92.0-2.01.81.62.1-1.6
Progressive ratio test 2 active lever presses2.32.53.3-1.7-1.8-1.8-1.7-1.8-1.8-1.81.71.81.8-1.8-1.51.51.41.61.41.7-1.51.2-1.21.31.01.7-1.1
Progressive ratio test 2 breakpoint3.03.44.3-2.0-2.1-2.0-1.9-2.0-2.0-2.01.92.02.0-2.0-1.71.81.71.91.72.0-1.81.5-1.51.51.22.0-1.3
Progressive ratio test 2 inactive lever presses2.63.03.6-1.9-1.9-1.9-1.8-1.9-1.9-1.91.81.91.9-1.9-1.51.71.51.81.51.8-1.61.6-1.61.51.31.7-1.4
Incentive Sensitization - Responses0.10.10.20.10.0-0.00.1-0.1-0.1-0.1-0.1-0.1-0.10.10.5-0.1-0.3-0.2-0.4-0.10.2-0.50.5-0.1-0.4-0.10.2
Incentive Sensitization - Breakpoint0.00.00.1-0.1-0.1-0.2-0.1-0.2-0.2-0.20.10.10.1-0.10.3-0.0-0.2-0.0-0.30.10.1-0.40.4-0.0-0.30.10.1
Sum of active levers in priming session hrs 5-60.10.10.2-0.2-0.2-0.2-0.2-0.2-0.2-0.20.20.30.3-0.3-0.20.20.20.30.20.3-0.20.4-0.40.20.30.1-0.4
Progressive ratio0.10.10.4-0.2-0.2-0.2-0.1-0.2-0.2-0.20.20.00.1-0.1-0.10.20.10.10.10.1-0.20.3-0.30.40.4-0.7-0.5
Food seeking constrained by brief footshock0.30.40.6-0.7-0.8-0.8-0.6-0.8-0.8-0.80.60.50.6-0.6-0.70.60.70.60.70.6-0.60.6-0.60.70.5-0.2-0.5
Seeking ratio, punishment vs. effort0.00.00.1-0.1-0.2-0.1-0.1-0.1-0.1-0.10.10.20.2-0.2-0.2-0.00.20.20.20.10.0-0.00.0-0.1-0.20.30.2
Retroperitoneal fat weight0.51.63.5-1.3-1.3-1.3-1.0-1.3-1.3-1.31.01.21.3-1.3-1.31.21.41.21.41.3-1.30.7-0.71.91.6-0.3-1.4
Reaction time number correct1.62.33.41.61.81.71.41.71.71.7-1.4-1.6-1.61.61.7-1.4-1.7-1.3-1.7-1.61.5-1.21.1-1.6-1.4-0.81.1
Reaction time mean minus median8.411.113.0-3.5-3.4-3.4-3.3-3.4-3.4-3.43.33.43.4-3.4-3.33.43.23.33.33.4-3.53.3-3.23.53.62.0-3.5
Reaction time mean minus median AUC6.18.09.5-2.9-2.8-2.8-2.8-2.8-2.8-2.82.83.02.9-2.9-2.72.92.72.92.83.0-3.02.8-2.82.93.11.7-2.9
Reaction time num false alarms1.62.23.2-1.5-1.4-1.4-1.5-1.4-1.4-1.41.51.41.5-1.5-1.41.61.51.41.41.5-1.61.8-1.81.41.61.1-1.7
Reaction time num false alarms AUC2.43.34.6-1.8-1.7-1.7-1.8-1.7-1.7-1.71.81.81.8-1.8-1.71.91.81.81.71.9-1.92.1-2.11.92.11.0-2.1
Reaction time trials correct on left1.62.33.41.61.81.71.41.71.71.7-1.4-1.6-1.61.61.7-1.4-1.7-1.3-1.7-1.61.5-1.21.1-1.6-1.4-0.81.1
Reaction time trials on left1.31.82.81.41.71.51.21.51.51.5-1.2-1.4-1.51.51.5-1.2-1.5-1.1-1.5-1.41.4-1.00.9-1.5-1.2-0.70.9
Reaction time mean0.70.91.2-1.0-1.1-1.0-0.9-1.0-1.0-1.00.91.11.1-1.1-0.90.90.91.00.91.1-1.00.8-0.81.11.00.4-0.8
Reaction time mean AUC0.40.50.8-0.8-0.8-0.8-0.6-0.7-0.7-0.70.60.80.9-0.9-0.70.70.60.70.70.8-0.80.5-0.50.90.80.1-0.6
Median of all reaction times0.00.00.10.0-0.00.00.10.10.10.1-0.10.00.0-0.00.1-0.1-0.2-0.1-0.1-0.00.0-0.30.3-0.0-0.1-0.30.2
Reaction time omissions9.713.214.3-3.8-3.6-3.7-3.7-3.7-3.7-3.73.73.63.6-3.6-3.53.83.53.73.63.6-3.73.7-3.63.73.72.8-3.6
Reaction time false alarm rate2.83.94.7-2.0-2.0-2.0-1.9-2.0-2.0-2.01.92.02.1-2.1-2.02.02.01.92.02.1-2.12.1-2.02.12.21.0-2.1
Reaction time premature initiation rate6.38.410.8-3.0-3.3-3.2-3.0-3.2-3.2-3.23.03.02.9-2.9-3.02.83.12.83.12.8-2.82.7-2.72.62.12.9-2.1
Reaction time premature initiations2.83.95.2-2.1-2.1-2.1-2.1-2.1-2.1-2.12.12.01.9-1.9-2.02.02.12.02.01.9-1.92.0-2.11.61.32.3-1.4
Std. dev. reaction times6.28.79.9-3.1-3.0-3.0-2.9-3.0-3.0-3.02.93.13.0-3.0-2.83.02.83.02.93.1-3.12.9-2.93.13.11.8-3.0
Reaction time trials completed1.31.82.81.41.71.51.21.51.51.5-1.2-1.4-1.51.51.5-1.2-1.5-1.1-1.5-1.41.4-1.00.9-1.5-1.2-0.70.9
Reaction time trials AUC2.02.84.11.82.01.91.61.91.91.9-1.6-1.7-1.81.81.9-1.6-1.9-1.5-1.9-1.81.7-1.31.2-1.8-1.5-0.91.3
Run reversals in cocaine runway, females0.00.00.2-0.0-0.2-0.1-0.1-0.1-0.1-0.10.1-0.00.1-0.1-0.10.00.10.10.10.1-0.00.1-0.0-0.1-0.00.40.1
Run reversals in cocaine runway, males1.41.41.7-1.2-1.2-1.2-1.2-1.2-1.2-1.21.31.11.1-1.1-1.31.21.21.11.21.1-1.21.3-1.31.11.01.2-0.9
Latency to leave start box in cocaine runway0.00.00.1-0.0-0.1-0.1-0.1-0.1-0.1-0.10.1-0.00.1-0.1-0.10.10.10.00.10.1-0.10.2-0.2-0.00.20.0-0.2
Latency to leave start box in cocaine runway, F1.71.92.5-1.4-1.4-1.3-1.5-1.3-1.3-1.31.51.41.3-1.3-1.41.41.31.41.31.3-1.41.5-1.51.01.11.6-1.2
Latency to leave start box in cocaine runway, M1.91.92.51.41.41.41.51.41.41.4-1.5-1.5-1.41.41.4-1.4-1.4-1.5-1.4-1.31.3-1.41.4-1.1-1.0-1.61.0
Std. dev. time between licks in bursts0.91.11.6-1.1-1.1-1.1-1.2-1.1-1.1-1.11.21.11.0-1.0-1.11.11.11.01.11.0-1.01.0-1.00.80.71.3-0.6
Total sessions with >9 infusions0.80.81.6-1.0-1.1-1.2-0.9-1.3-1.3-1.30.90.80.8-0.8-0.90.90.80.80.90.8-0.90.6-0.61.20.70.4-0.5
Short access day 1 total inactive lever presses1.51.72.3-1.4-1.5-1.4-1.3-1.4-1.4-1.41.31.41.4-1.4-1.31.21.31.31.31.4-1.31.0-1.01.31.00.8-1.0
Short access day 10 total inactive lever presses0.30.42.1-0.5-0.6-0.4-0.6-0.4-0.4-0.40.60.70.7-0.7-0.70.50.70.70.60.7-0.50.7-0.7-0.10.11.5-0.2
Short access day 1 total infusions0.10.10.2-0.3-0.3-0.4-0.1-0.4-0.4-0.40.10.20.2-0.2-0.20.20.10.10.20.2-0.1-0.00.00.50.1-0.3-0.0
Short access day 10 total infusions0.91.01.7-1.1-1.2-1.2-0.9-1.3-1.3-1.30.90.90.9-0.9-1.01.01.00.91.00.9-1.00.6-0.71.30.90.2-0.8
Short access total infusions0.50.51.1-0.8-0.9-1.0-0.7-1.0-1.0-1.00.70.60.6-0.6-0.70.70.70.50.70.6-0.60.4-0.40.90.40.2-0.4
Short access day 1 locomotion0.10.10.3-0.4-0.5-0.5-0.4-0.5-0.5-0.50.40.30.3-0.3-0.50.20.30.30.40.3-0.20.1-0.10.2-0.10.40.2
Short access day 10 total locomotion0.30.33.1-0.4-0.5-0.4-0.6-0.4-0.4-0.40.60.40.4-0.4-0.60.30.40.40.50.3-0.30.6-0.6-0.3-0.41.80.3
Short access total locomotion0.50.51.9-0.7-0.9-0.8-0.8-0.9-0.9-0.90.80.70.7-0.7-0.80.60.70.70.70.6-0.50.6-0.60.2-0.01.40.1
One hour access (0.3 mA shock)0.20.30.6-0.6-0.7-0.7-0.5-0.8-0.8-0.80.50.50.5-0.5-0.50.50.50.40.50.5-0.50.1-0.10.70.4-0.1-0.3
Compulsive drug intake0.90.91.31.01.11.11.11.21.21.2-1.1-0.9-0.90.90.9-1.0-0.9-1.0-0.8-0.90.9-0.80.8-0.8-0.6-0.90.7
One hour access (shock baseline)0.20.20.5-0.5-0.6-0.7-0.4-0.7-0.7-0.70.40.30.3-0.3-0.20.40.30.30.30.3-0.3-0.00.00.60.2-0.1-0.2
Social response proportion0.10.10.3-0.4-0.5-0.5-0.3-0.5-0.5-0.50.30.40.4-0.4-0.30.30.30.30.30.4-0.40.3-0.40.50.3-0.1-0.3
Social responses7.79.911.6-3.3-3.4-3.3-3.2-3.3-3.3-3.33.33.33.2-3.2-3.33.13.33.13.33.2-3.13.1-3.22.82.62.8-2.6
Social time0.10.11.1-0.2-0.1-0.20.1-0.2-0.2-0.2-0.10.10.1-0.1-0.00.10.10.10.10.1-0.20.0-0.10.60.6-1.0-0.7
Soleus weight0.61.62.11.31.21.31.31.31.31.3-1.3-1.2-1.21.21.3-1.4-1.3-1.3-1.3-1.21.4-1.31.4-1.5-1.4-0.91.4
Bone: stiffness17.026.828.75.35.35.45.35.35.35.3-5.2-5.2-5.35.35.3-5.2-5.4-5.2-5.3-5.35.2-5.15.1-5.0-4.8-4.54.5
Tibialis anterior weight0.93.06.61.70.91.41.81.41.41.4-1.8-1.7-1.31.31.3-2.0-1.3-1.9-1.3-1.41.8-2.42.5-1.9-2.5-1.22.6
Time to tail flick, vehicle, before self-admin0.91.01.5-1.0-0.9-0.9-1.0-0.9-0.9-0.91.00.90.8-0.8-1.01.01.00.91.00.9-1.01.2-1.11.01.00.8-1.2
Time to tail flick, vehicle, after self-admin0.30.30.90.50.50.50.40.50.50.5-0.4-0.4-0.50.50.5-0.5-0.5-0.4-0.5-0.50.6-0.50.5-0.8-0.90.31.0
Time to tail flick, test, before self-admin0.40.40.7-0.6-0.5-0.6-0.6-0.6-0.6-0.60.60.70.6-0.6-0.50.60.50.70.50.6-0.60.6-0.50.70.80.6-0.7
Time to tail flick, test, after self-admin0.20.20.60.40.50.40.50.40.40.4-0.5-0.4-0.50.50.5-0.4-0.5-0.4-0.5-0.50.4-0.40.4-0.3-0.2-0.80.2
Delta time to tail flick, vehicle, before/after SA0.40.40.80.60.60.60.70.60.60.6-0.7-0.6-0.60.60.7-0.7-0.7-0.6-0.7-0.60.7-0.70.7-0.7-0.8-0.40.9
Delta time to tail flick, test, before/after SA0.20.20.40.40.40.50.40.40.40.4-0.4-0.5-0.50.50.4-0.4-0.4-0.5-0.4-0.50.4-0.30.3-0.5-0.5-0.60.4
Tibia length7.320.722.94.64.44.54.64.54.54.5-4.6-4.6-4.64.64.6-4.7-4.6-4.8-4.6-4.64.6-4.64.6-4.5-4.6-3.94.5
Ambulatory time before self-admin4.04.26.6-2.1-2.1-2.1-2.1-2.0-2.0-2.02.12.22.2-2.2-2.12.02.12.22.12.1-2.02.0-1.91.61.52.6-1.5
Ambulatory time after self-admin1.71.93.5-1.4-1.4-1.4-1.5-1.4-1.4-1.41.51.41.4-1.4-1.41.31.41.41.41.4-1.41.3-1.31.00.91.9-1.0
Bone: tissue strength1.11.01.51.11.21.21.01.21.21.2-1.0-1.0-1.01.01.1-1.0-1.2-0.9-1.2-1.01.0-0.70.7-1.1-0.9-0.40.8
Total heroin consumption1.92.34.41.51.31.41.41.41.41.4-1.4-1.4-1.41.41.3-1.6-1.4-1.4-1.4-1.51.7-1.71.7-1.9-1.9-0.22.1
Bone: trabecular number6.510.216.53.23.63.53.43.43.43.4-3.3-3.2-3.33.33.5-3.0-3.4-3.1-3.4-3.22.9-2.92.8-2.5-2.1-4.11.7
Bone: trabecular spacing2.43.17.0-1.7-2.0-1.9-1.9-1.9-1.9-1.91.91.81.8-1.8-1.91.61.91.71.91.7-1.51.6-1.51.20.82.6-0.6
Bone: trabecular thickness0.10.10.5-0.4-0.2-0.3-0.3-0.3-0.3-0.30.20.40.2-0.2-0.20.40.30.30.30.3-0.50.3-0.30.70.7-0.4-0.6
Bone: trabecular tissue density0.10.11.1-0.1-0.2-0.2-0.4-0.2-0.2-0.20.40.10.1-0.1-0.20.30.20.30.20.0-0.20.3-0.3-0.1-0.11.10.2
Water consumed over 24 hours0.00.00.10.20.30.20.10.20.20.2-0.1-0.2-0.30.30.2-0.0-0.2-0.1-0.2-0.20.10.0-0.10.00.1-0.4-0.1
Number of responses in last shaping day0.10.10.60.1-0.10.00.10.00.00.0-0.1-0.0-0.00.00.1-0.3-0.2-0.0-0.1-0.10.3-0.40.4-0.4-0.70.20.8