Plxnc1

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 OFC mRNA stability Plxnc1 0.19 0.11 6.5e-03 0.05 0.08 0.08 0.05 3.0e-02 5.7e-03 6.4e-03 2.3e-02
2 BLA mRNA stability Plxnc1 0.08 0.06 6.1e-03 0.07 0.03 0.03 0.05 2.2e-04 1.5e-02 1.2e-02 1.0e-03
3 BLA alternative polyA NM_001426988.1 0.09 0.05 5.6e-04 0.05 0.05 0.05 0.06 1.4e-03 1.4e-03 1.7e-03 6.7e-04
4 BLA alternative polyA NM_001426988.1 0.08 0.05 1.0e-03 0.07 0.04 0.04 0.05 1.9e-04 2.0e-03 2.1e-03 1.2e-03
5 BLA alternative polyA XM_039080101.2 0.1 0.06 4.0e-04 0.07 0.05 0.04 0.04 2.1e-04 8.8e-04 3.3e-03 2.1e-03
6 BLA alternative polyA XM_039080101.2 0.1 0.06 8.4e-04 0.05 0.05 0.04 0.04 1.1e-03 1.4e-03 4.5e-03 2.5e-03
7 pVTA alternative TSS NM_001426988.1 0.17 0.07 7.9e-04 0.05 0.02 0.02 0.03 4.3e-05 8.4e-03 1.1e-02 1.2e-03
8 IC mRNA stability Plxnc1 0.14 0.07 8.5e-04 0 0.06 0 0.04 2.0e-01 1.8e-03 2.0e-01 9.6e-03
9 NAcc gene expression Plxnc1 0.09 0.04 5.6e-17 0.08 0.12 0.12 0.12 1.0e-11 2.8e-17 3.1e-17 3.2e-17
10 pVTA alternative TSS NM_001426988.1 0.18 0.08 1.0e-03 0.02 0.03 0.02 0.03 1.8e-02 3.1e-03 4.9e-03 2.1e-03
11 Adipose gene expression Plxnc1 0.04 0.02 1.3e-03 0.01 0.01 0.01 0.01 7.8e-03 7.6e-03 3.7e-02 2.3e-02
12 LHb gene expression Plxnc1 0.38 0.13 1.0e-05 0.18 0.2 0.16 0.17 4.9e-05 1.8e-05 1.5e-04 8.3e-05
13 pVTA gene expression Plxnc1 0.14 0.07 3.2e-07 0.07 0.08 0.08 0.07 3.3e-06 3.0e-07 4.8e-07 3.4e-06
14 pVTA alternative TSS XM_039080102.2 0.13 0.07 8.0e-03 0.02 0.01 0.01 0.02 1.2e-02 9.3e-02 5.3e-02 1.8e-02
15 pVTA alternative TSS XM_039080102.2 0.13 0.06 4.3e-03 0.01 0.01 0.01 0.02 2.1e-02 2.9e-02 5.9e-02 9.4e-03
16 BLA gene expression Plxnc1 0.19 0.09 1.4e-08 0.15 0.15 0.16 0.16 2.2e-08 2.4e-08 1.3e-08 1.1e-08
17 Brain gene expression Plxnc1 0.04 0.02 1.4e-03 0.03 0.03 0.03 0.03 5.5e-04 9.1e-04 2.0e-03 1.6e-03
18 IC gene expression Plxnc1 0.09 0.05 3.2e-03 0.02 0.03 0.01 0.02 6.0e-02 1.6e-02 1.3e-01 6.5e-02
19 PL gene expression Plxnc1 0.04 0.02 7.2e-03 0.01 0.02 0.02 0.01 1.4e-02 2.5e-03 2.5e-03 9.9e-03

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19
Bone: apparent density0.10.20.7-0.40.90.10.1-0.1-0.10.5-0.3-0.20.8-0.3-0.6-0.60.60.40.0-0.0-0.5-0.4
Area under the delay curve0.91.03.10.71.20.30.5-0.5-0.5-0.11.51.00.51.60.20.2-0.9-0.81.21.81.81.1
BMI with tail1.86.419.04.41.92.83.1-3.1-3.1-1.84.2-1.9-2.53.7-1.1-0.8-2.4-1.5-0.30.52.60.3
BMI without tail3.510.625.45.03.14.64.4-4.4-4.4-3.43.8-3.8-3.53.0-3.1-2.7-0.50.6-2.2-1.40.4-0.8
Body weight9.240.4103.810.28.28.78.5-8.5-8.5-6.77.2-6.8-5.46.3-5.7-4.9-3.0-0.6-4.0-2.41.5-1.4
Weight adjusted by age0.60.93.4-0.90.9-0.7-0.80.80.81.1-1.90.31.1-1.6-0.10.5-1.0-1.1-0.6-0.6-0.9-1.2
Bone surface0.30.61.81.31.00.80.9-0.9-0.9-0.81.4-0.6-0.51.2-0.7-0.6-0.00.1-0.10.30.60.1
Bone volume0.20.41.01.00.90.70.8-0.8-0.8-0.31.0-0.6-0.20.9-0.7-0.6-0.00.0-0.10.20.4-0.2
Breakpoint value in progressive ratio session2.02.35.7-1.4-1.5-2.4-2.12.12.11.5-0.91.80.8-0.61.71.5-1.0-1.21.81.31.10.5
Number of licking bursts0.40.61.71.00.41.01.3-1.3-1.3-0.41.3-0.6-0.21.1-0.1-0.4-0.5-0.40.1-0.10.9-0.5
Context. condit. distance diff. score0.70.82.80.90.20.70.3-0.3-0.3-1.61.3-0.3-1.71.1-0.2-0.51.41.5-0.1-0.30.10.6
Locomotion velocity, session 11.92.14.9-2.0-0.8-1.9-1.81.81.82.2-2.11.11.9-1.90.70.7-0.8-1.20.40.4-0.6-0.4
Locomotion distance, session 10.70.83.2-0.20.6-1.1-0.90.90.91.3-0.50.41.7-0.20.30.2-1.8-1.8-0.00.40.4-0.2
Locomotion velocity, session 20.50.51.2-0.80.2-0.6-1.11.11.1-0.4-1.10.20.0-1.00.20.41.01.00.2-0.5-0.90.3
Locomotion distance, session 20.60.84.41.11.4-0.30.0-0.0-0.00.40.5-0.31.20.8-0.2-0.0-2.1-1.8-0.20.10.9-0.6
Locomotion velocity, session 30.30.41.5-1.00.4-0.4-0.60.60.60.2-1.20.60.8-1.00.10.10.40.30.10.3-0.80.5
Locomotion distance, session 30.40.52.40.91.50.30.5-0.5-0.5-0.50.80.20.21.1-0.00.0-1.1-0.80.20.20.80.1
Stereotopy head waving bouts, day 30.70.92.3-1.5-0.2-1.1-1.21.21.20.8-1.40.51.3-1.30.1-0.21.00.60.20.4-0.90.2
Stereotopy head waving duration, day 30.70.92.9-1.5-0.6-0.7-0.90.90.90.7-1.60.20.9-1.7-0.1-0.21.20.8-0.00.2-1.30.0
Locomotion velocity, session 70.30.32.0-0.00.5-0.4-0.30.30.30.0-0.30.20.70.10.40.3-1.4-1.20.1-0.70.4-0.9
Locomotion distance, session 70.20.31.40.00.2-0.5-0.50.50.50.0-0.10.50.50.30.40.5-1.2-1.00.1-0.40.6-0.3
Stereotopy head waving bouts, day 70.60.62.4-1.10.8-0.4-0.50.50.50.9-1.5-0.11.3-1.5-0.2-0.10.2-0.1-0.3-0.2-1.2-0.7
Stereotopy head waving duration, day 70.40.51.8-0.90.4-0.2-0.10.10.11.1-1.3-0.11.3-1.3-0.20.1-0.4-0.6-0.00.2-0.8-0.5
Locomotion velocity, session 80.40.51.5-0.1-0.60.60.0-0.0-0.0-0.8-0.6-0.5-1.2-0.8-0.6-0.41.21.2-0.8-0.9-1.10.0
Locomotion distance, session 81.21.76.02.42.21.31.3-1.3-1.3-1.31.9-0.9-0.62.1-0.8-1.0-1.1-0.5-0.6-0.50.9-0.1
Degree of sensitization distance0.30.32.4-0.5-1.6-0.6-0.70.70.7-0.0-0.30.3-0.6-0.30.50.50.30.30.2-0.10.10.2
Degree of sensitization stereotypy0.30.41.3-1.00.2-0.5-0.60.60.60.6-1.20.20.7-1.10.30.50.30.10.20.2-0.7-0.2
Conditioned locomotion0.20.20.60.1-0.1-0.4-0.60.60.6-0.60.30.1-0.40.40.40.30.80.80.30.30.20.6
Cocaine response after cond. corrected0.60.83.11.00.01.10.8-0.8-0.8-1.31.1-0.8-1.70.6-0.9-0.40.91.0-0.5-0.00.00.1
Cocaine response after cond. not corrected0.60.71.71.20.31.21.0-1.0-1.0-1.01.1-0.8-1.30.7-1.0-0.70.40.6-0.6-0.20.1-0.0
Cocaine response before conditioning0.20.21.0-0.20.0-0.2-0.10.10.10.8-0.40.21.0-0.30.1-0.2-1.0-1.0-0.2-0.1-0.0-0.2
Saline control response0.50.71.40.61.21.11.1-1.1-1.1-0.30.1-1.00.1-0.1-1.0-0.8-0.10.1-1.2-1.0-0.7-0.8
Bone: connectivity density0.30.41.7-1.00.2-0.1-0.20.20.20.2-1.00.00.5-1.1-0.4-0.51.31.0-0.0-0.5-1.2-0.4
Bone: cortical apparent density0.10.10.40.30.6-0.2-0.10.10.1-0.30.0-0.30.00.20.2-0.3-0.5-0.30.2-0.3-0.1-0.1
Bone: cortical area1.01.54.22.11.61.41.6-1.6-1.6-0.51.7-1.0-0.11.6-1.3-1.2-1.0-0.7-0.80.10.8-0.2
Bone: cortical porosity0.10.10.60.30.30.3-0.00.00.0-0.6-0.0-0.5-0.3-0.2-0.8-0.20.40.6-0.3-0.0-0.50.2
Bone: cortical porosity0.10.10.50.50.30.30.2-0.2-0.2-0.30.1-0.4-0.0-0.0-0.70.0-0.3-0.1-0.10.2-0.10.1
Bone: cortical thickness0.50.92.21.01.51.11.3-1.3-1.30.20.3-0.80.60.3-1.4-1.0-0.9-0.7-1.0-0.3-0.2-0.6
Bone: cortical thickness0.30.30.8-0.5-0.8-0.9-0.90.90.90.6-0.60.40.1-0.60.20.7-0.1-0.30.30.6-0.00.2
Bone: cortical tissue density0.10.10.40.30.6-0.2-0.10.10.1-0.3-0.0-0.4-0.00.10.1-0.4-0.4-0.20.2-0.4-0.2-0.2
Condit. Reinf. active minus inactive responses2.02.36.9-1.9-1.4-1.8-1.31.31.32.6-1.71.32.3-1.51.01.1-1.7-2.10.60.80.0-0.3
Condit. Reinf. active-inactive response ratio1.31.44.8-1.4-1.2-1.2-0.60.60.62.2-1.01.21.9-0.80.91.2-1.3-1.70.81.30.5-0.1
Condit. Reinf. active responses2.63.39.1-2.5-1.8-2.3-1.81.81.83.0-2.31.52.3-2.11.21.4-1.5-2.00.80.6-0.2-0.5
Condit. Reinf. inactive responses1.31.63.4-1.8-1.6-1.8-1.71.71.71.5-1.71.00.8-1.50.91.1-0.4-0.70.70.0-0.3-0.1
Incentive salience index mean1.92.39.8-1.5-0.3-1.3-0.50.50.53.1-1.80.63.0-1.60.20.3-2.4-2.8-0.10.2-0.3-1.2
Condit. Reinf. lever presses1.21.66.8-0.51.0-0.30.4-0.4-0.42.4-1.3-0.22.6-1.1-0.6-0.5-2.1-2.3-0.7-0.1-0.5-1.5
Condit. Reinf. active minus inactive responses1.21.64.3-1.2-1.0-1.6-1.31.31.32.1-1.40.81.9-1.11.01.2-1.6-1.80.40.10.2-0.6
Condit. Reinf. active-inactive response ratio0.40.51.4-0.8-0.6-0.6-0.50.50.51.2-1.10.11.1-1.1-0.10.2-0.4-0.6-0.3-0.2-0.6-0.7
Condit. Reinf. active responses0.91.23.1-0.8-1.0-1.3-1.11.11.11.6-0.90.91.4-0.51.31.3-1.6-1.80.50.30.7-0.4
Condit. Reinf. inactive responses0.81.12.8-0.6-1.5-1.2-1.21.21.20.7-0.31.30.2-0.01.71.5-0.9-0.91.01.01.10.7
Condit. Reinf. lever presses0.70.92.6-0.7-0.2-1.2-1.11.11.11.1-1.20.41.6-0.80.91.2-1.2-1.20.2-0.40.1-0.5
Condit. Reinf. lever reinforcers received1.01.43.9-0.6-1.0-1.5-1.21.21.21.6-0.70.91.5-0.21.51.4-1.9-2.00.70.41.0-0.2
Conditioned reinforcement - actives0.60.92.8-0.00.60.90.8-0.8-0.80.8-1.1-1.01.1-1.1-1.1-1.0-0.3-0.4-1.3-0.8-1.3-1.7
Conditioned reinforcement - inactives0.10.20.6-0.10.60.0-0.40.40.4-0.1-0.5-0.40.4-0.5-0.5-0.80.40.5-0.30.0-0.7-0.2
Conditioned locomotion0.40.51.10.70.80.90.9-0.9-0.9-0.7-0.3-0.9-0.2-0.1-0.8-0.7-0.3-0.1-1.0-0.5-0.7-0.8
Patch foraging indifference point 0 sec0.20.43.10.31.80.90.7-0.7-0.7-0.3-0.1-0.50.3-0.1-0.8-0.60.30.4-0.4-0.6-0.5-0.7
Patch foraging indifference point AUC0.40.61.70.41.30.70.6-0.6-0.6-0.2-0.1-1.10.6-0.2-1.1-1.00.30.3-1.3-1.1-0.9-1.0
Delay disc. indifference point, 0s delay0.60.62.2-0.31.2-0.5-0.20.20.21.0-0.50.61.4-0.30.20.4-1.5-1.51.00.90.6-0.1
Delay disc. indifference point, 16s delay1.71.86.11.41.00.40.7-0.7-0.7-0.42.40.90.12.50.4-0.0-1.0-0.81.52.22.41.5
Delay disc. indifference point, 2s delay0.30.32.00.51.40.60.6-0.6-0.6-0.20.50.20.20.5-0.3-0.3-1.0-0.80.20.30.40.0
Delay disc. indifference point, 24s delay1.01.13.21.10.41.21.1-1.1-1.1-0.81.80.3-0.21.7-0.4-1.10.40.50.71.41.11.3
Delay disc. indifference point, 4s delay0.20.20.40.20.60.60.6-0.6-0.6-0.20.20.3-0.10.2-0.30.3-0.5-0.4-0.10.40.20.3
Delay disc. indifference point, 8s delay0.80.94.10.50.80.10.1-0.1-0.1-0.61.31.2-0.11.40.40.7-0.2-0.11.32.01.61.6
Indifference point function ln k0.30.61.60.4-1.1-0.3-0.40.40.4-0.60.80.5-1.30.80.80.7-0.10.10.80.91.01.3
Indifference point function log k0.30.61.60.4-1.1-0.3-0.40.40.4-0.60.80.5-1.30.80.80.7-0.10.10.80.91.01.3
Patch foraging total patch changes 0 sec0.20.42.80.21.70.80.7-0.7-0.7-0.3-0.2-0.50.3-0.2-0.8-0.50.10.2-0.4-0.6-0.5-0.6
Patch foraging total patch changes 12 sec1.92.57.50.62.41.31.5-1.5-1.50.7-0.6-1.71.5-0.7-2.1-1.5-0.9-0.9-1.9-2.3-1.4-2.7
Patch foraging total patch changes 18 sec1.72.66.90.62.61.91.7-1.7-1.7-0.7-0.4-1.90.4-0.6-2.1-1.80.50.7-2.1-2.3-1.9-2.0
Patch foraging total patch changes 24 sec1.42.55.01.12.22.22.1-2.1-2.1-0.60.2-1.90.1-0.2-2.1-1.7-0.10.1-1.7-2.1-1.3-1.7
Patch foraging total patch changes 6 sec0.40.61.90.20.81.11.4-1.4-1.40.10.1-0.70.2-0.1-0.7-0.60.30.3-0.5-0.7-0.3-1.0
Patch foraging time to switch 0 sec0.00.10.3-0.10.00.30.5-0.5-0.50.00.0-0.10.40.0-0.1-0.20.0-0.0-0.1-0.1-0.2-0.2
Patch foraging water rate 0 sec0.81.64.92.22.21.11.2-1.2-1.2-0.31.6-1.2-0.31.5-1.1-1.1-1.9-1.5-0.4-0.20.9-0.8
Patch foraging water rate 12 sec1.02.15.11.91.61.71.5-1.5-1.5-1.11.5-2.2-1.01.0-1.8-1.80.30.5-1.6-1.6-0.4-1.5
Patch foraging water rate 18 sec0.20.20.70.6-0.2-0.3-0.40.40.4-0.20.7-0.1-0.70.60.30.3-0.4-0.30.60.60.80.4
Patch foraging water rate 24 sec1.62.37.22.72.51.51.6-1.6-1.6-1.32.0-1.5-0.91.9-1.2-1.6-1.5-0.9-0.4-0.60.8-0.4
Patch foraging water rate 6 sec2.94.312.43.52.62.42.3-2.3-2.3-1.82.9-2.4-1.62.4-1.7-1.9-1.5-0.8-1.1-1.10.9-1.0
Seeking ratio, delayed vs. immediate footshock0.30.43.3-0.60.2-0.4-0.30.30.30.9-0.60.01.8-0.5-0.3-0.80.0-0.2-0.1-0.1-0.3-0.5
Distance traveled before self-admin0.20.31.30.30.50.30.6-0.6-0.60.60.20.10.50.3-0.1-0.2-1.1-1.10.30.20.4-0.1
Distance traveled after self-admin0.81.02.50.20.7-0.4-0.20.20.20.50.51.40.90.90.90.8-1.3-1.31.61.51.61.5
Extensor digitorum longus weight0.20.92.71.7-0.11.01.0-1.0-1.0-1.01.6-0.9-1.41.3-0.8-0.30.20.50.20.60.70.4
Bone: elastic displacement3.44.09.1-2.8-3.0-2.6-2.92.92.91.5-1.92.20.4-1.91.52.01.00.51.31.3-0.31.2
Bone: elastic work1.62.15.1-1.9-2.0-1.8-2.32.32.30.8-1.41.60.3-1.40.71.41.20.80.90.8-0.31.0
Bone: endosteal estimation1.43.012.11.90.10.0-0.10.10.1-2.23.30.6-1.73.51.30.60.60.81.71.83.02.0
Bone: endosteal perimeter2.04.215.33.41.31.92.0-2.0-2.0-2.63.9-0.8-2.23.8-0.3-0.8-0.30.30.10.82.51.1
Epididymis fat weight1.44.813.33.62.72.53.1-3.1-3.1-1.42.9-1.8-1.22.8-1.1-1.3-2.2-1.5-0.8-0.51.6-0.9
Delta time in closed arm before/after self-admin0.30.30.70.8-0.80.50.8-0.8-0.8-0.10.9-0.4-0.60.8-0.0-0.2-0.4-0.3-0.30.00.50.4
Delta time in open arm before/after self-admin1.41.43.5-1.9-0.7-1.7-1.51.51.50.8-1.31.41.1-1.11.21.60.60.31.10.80.10.1
Diff in mean of infusions in LGA sessions1.01.35.1-1.4-1.3-1.2-0.80.80.82.3-1.50.71.5-1.50.50.8-1.0-1.30.4-0.0-0.2-0.9
Delay discount exponential model param0.80.92.4-0.8-1.0-0.5-0.60.60.60.4-1.5-0.8-0.1-1.5-0.0-0.10.60.5-1.0-1.6-1.5-1.2
Extinction: sum of active levers before priming0.20.30.6-0.3-0.4-0.7-0.80.80.80.20.00.6-0.00.00.60.4-0.2-0.20.70.70.50.3
Active lever presses in extinction session 60.80.82.8-0.10.6-1.1-0.70.70.70.9-0.10.81.20.30.70.9-1.6-1.71.00.61.10.0
Bone: final force0.61.04.81.51.20.20.3-0.3-0.3-0.42.1-0.10.52.2-0.1-0.3-0.6-0.40.40.91.70.7
Bone: final moment0.50.83.41.31.20.00.2-0.2-0.20.11.8-0.10.91.9-0.3-0.4-0.7-0.70.40.81.50.4
Food consumed during 24 hour testing period0.81.14.10.8-0.21.31.0-1.0-1.0-1.40.5-1.2-2.00.2-0.5-0.61.31.5-1.0-1.1-0.7-0.1
Glucose0.10.10.5-0.3-0.7-0.5-0.40.40.40.5-0.20.00.3-0.20.20.0-0.0-0.20.2-0.2-0.00.1
Heart weight1.62.57.62.42.51.11.5-1.5-1.5-0.82.0-0.40.22.3-0.40.1-2.8-2.10.20.61.90.3
Delay discount hyperbolic model param0.80.82.1-0.9-1.3-0.7-0.70.70.70.4-1.5-0.7-0.2-1.50.20.00.90.7-0.7-1.3-1.4-1.0
Intermittent access intake day 1-15 change0.91.84.41.01.21.11.6-1.6-1.60.8-0.4-1.70.4-0.6-1.6-1.0-1.5-1.4-1.7-1.6-1.0-2.1
Intermittent access intake escalation0.91.84.30.91.21.11.6-1.6-1.61.0-0.4-1.60.5-0.6-1.6-1.1-1.7-1.5-1.6-1.5-1.0-2.1
Intermittent access intake escalation 20.80.91.80.91.11.01.4-1.4-1.40.0-0.2-1.1-0.1-0.2-1.1-0.5-1.0-0.8-1.1-1.2-0.7-1.0
Intermitt. access day 1 inactive lever presses0.62.15.1-2.0-2.1-2.0-2.32.32.30.9-1.41.21.1-1.21.21.00.90.50.90.8-0.31.1
Intermitt. access day 15 inactive lever presses0.30.61.9-0.8-0.5-0.8-1.31.31.30.3-0.90.70.1-0.80.40.40.20.20.50.8-0.41.4
Intermitt. access escalation Index0.50.74.3-1.4-2.1-0.8-0.80.80.80.8-0.90.80.2-0.90.80.20.70.30.20.3-0.3-0.3
Intermittent access day 1 total infusions1.62.58.71.80.82.11.5-1.5-1.5-2.81.8-1.3-3.01.4-0.9-1.01.62.1-0.7-0.5-0.20.3
Intermittent access day 15 total infusions1.92.96.52.11.72.62.3-2.3-2.3-1.81.2-2.0-2.10.7-1.8-1.50.30.8-1.4-1.3-0.7-0.9
Intermittent access terminal intake (last 3 days)1.72.24.82.21.52.21.9-1.9-1.9-1.81.4-1.6-2.21.1-1.4-1.10.00.6-0.9-0.9-0.3-0.4
Intermittent access total infusions1.72.04.62.11.42.21.8-1.8-1.8-1.91.5-1.3-2.11.2-1.1-0.90.20.8-0.7-0.6-0.0-0.1
Intermittent access day 1 locomotion1.72.29.41.40.71.70.8-0.8-0.8-3.11.4-0.9-2.81.2-0.5-0.52.12.6-0.4-0.1-0.20.7
Intermittent access day 15 total locomotion1.12.15.00.81.42.01.4-1.4-1.4-1.9-0.2-1.4-1.4-0.3-1.4-1.42.02.2-1.4-1.1-1.7-0.3
Intermittent access total locomotion2.02.47.91.61.32.21.5-1.5-1.5-2.81.2-1.3-2.51.0-1.0-1.01.92.4-0.7-0.5-0.50.4
Intermittent access standard deviation1.32.86.41.92.02.32.5-2.5-2.5-0.70.7-2.0-0.70.5-1.9-1.3-0.9-0.5-1.7-1.6-0.7-1.5
Left kidney weight2.411.025.95.14.34.64.3-4.3-4.3-3.42.9-3.9-2.52.5-3.5-3.2-1.8-0.5-2.8-1.9-0.2-1.3
Right kidney weight2.29.926.75.24.14.04.1-4.1-4.1-3.33.8-3.1-2.43.6-2.5-2.4-2.1-0.9-1.8-1.01.2-0.7
Cocaine induced anxiety1.62.34.3-1.7-1.7-2.0-1.81.81.81.1-0.72.10.8-0.41.81.90.50.11.91.90.91.7
Post-drug Anxiety1.71.83.8-2.0-1.7-1.8-1.71.71.71.3-1.01.80.5-0.91.41.30.70.21.41.20.11.2
Baseline Anxiety0.60.72.10.60.60.90.8-0.8-0.8-0.40.1-1.1-0.5-0.3-1.1-1.4-0.10.0-1.2-1.4-1.0-1.1
Tail length7.930.863.76.86.78.06.9-6.9-6.9-6.33.5-6.9-4.52.5-6.5-6.31.43.0-5.5-4.8-2.8-2.6
Length with tail9.943.287.39.29.29.38.6-8.6-8.6-7.25.1-7.8-4.84.2-7.2-6.6-1.01.4-5.7-4.8-1.6-2.8
Length without tail4.715.038.46.26.05.25.0-5.0-5.0-4.33.9-4.1-2.83.6-3.6-3.1-1.9-0.4-2.7-1.90.6-1.2
Times rat made contact with spout2.93.37.41.81.71.82.1-2.1-2.10.60.8-2.70.60.3-2.4-2.7-0.6-0.6-2.4-2.1-1.0-2.7
Lifetime Intake1.82.24.92.11.62.22.0-2.0-2.0-1.91.7-1.2-2.01.4-1.1-1.00.20.7-0.6-0.50.2-0.3
Liver weight, left4.77.715.63.33.03.93.9-3.9-3.9-2.22.1-3.5-1.61.4-3.2-3.1-0.10.5-2.8-2.5-1.0-2.0
Liver weight, right2.54.39.52.62.42.82.5-2.5-2.5-1.50.9-3.1-1.50.4-2.7-2.3-0.40.2-2.5-2.2-1.3-1.8
Locomotor activity2.84.410.83.32.82.12.7-2.7-2.7-0.72.1-2.0-0.02.1-1.7-1.7-2.9-2.2-1.2-0.91.0-1.3
Locomotor testing distance1.73.17.42.72.01.52.3-2.3-2.3-0.22.3-1.30.22.3-0.9-1.1-2.7-2.2-0.3-0.01.7-0.6
Locomotor testing rearing0.51.02.31.41.31.01.5-1.5-1.50.10.7-0.90.10.7-1.0-0.7-1.4-1.2-0.8-0.30.3-0.8
Locomotion in novel chamber0.30.43.0-0.2-0.7-0.0-0.00.00.01.00.4-0.01.70.2-0.3-1.40.0-0.20.20.30.00.0
Locomotion in novel chamber post-restriction0.61.03.50.5-0.01.20.9-0.9-0.9-1.50.8-0.6-1.90.4-0.4-1.01.81.8-0.2-0.2-0.50.1
Fecal boli incidents, locomotor time 10.20.31.00.41.00.90.7-0.7-0.7-0.70.4-0.5-0.10.3-0.4-0.40.70.8-0.5-0.5-0.30.3
Change in fecal boli incidents, locomotor task1.81.73.8-0.9-1.4-1.6-1.51.51.50.50.11.90.20.51.91.8-0.6-0.81.71.51.51.2
Time >=10cm from walls, locomotor time 10.80.92.6-0.4-0.8-0.8-0.40.40.40.60.11.30.20.31.21.6-1.0-1.11.31.41.31.1
Bouts of movement, locomotor time 10.20.31.30.20.20.20.5-0.5-0.5-0.10.10.30.10.30.20.7-0.6-0.50.71.10.80.6
Total resting periods, locomotor time 10.20.21.0-0.30.1-0.10.1-0.1-0.10.4-0.60.50.6-0.30.20.9-0.6-0.60.61.00.40.5
Rest time, locomotor task time 11.01.23.5-1.8-0.6-1.1-1.11.11.11.5-1.91.21.4-1.60.71.10.1-0.30.60.8-0.50.7
Distance moved, locomotor task time 10.71.02.71.11.20.50.8-0.8-0.80.30.6-1.20.40.4-1.0-1.2-1.5-1.2-1.0-1.2-0.1-1.6
Vertical activity count, locomotor time 10.71.84.42.10.80.81.4-1.4-1.40.21.8-1.50.11.6-0.9-1.6-2.1-1.8-0.6-1.00.9-1.3
Time >=10cm from walls, locomotor time 21.11.76.2-1.8-0.6-0.8-0.50.50.52.5-2.10.22.3-2.1-0.20.1-0.9-1.4-0.2-0.3-1.2-1.4
Bouts of movement, locomotor time 20.30.51.90.70.40.1-0.10.10.1-1.30.60.4-1.40.70.20.9-0.7-0.30.50.70.80.8
Total resting periods, locomotor time 20.30.61.50.40.2-0.3-0.30.30.3-1.00.50.9-1.10.70.61.2-0.8-0.50.91.11.11.0
Rest time, locomotor task time 21.21.53.4-0.7-1.1-1.4-1.21.21.20.7-0.21.70.00.21.81.8-0.2-0.41.71.31.31.6
Distance moved, locomotor task time 21.11.33.90.10.70.70.9-0.9-0.90.6-0.9-1.60.6-1.2-1.5-1.4-0.7-0.6-1.5-1.6-1.5-2.0
Vertical activity count, locomotor time 22.53.47.11.81.71.72.3-2.3-2.30.10.7-2.70.70.3-2.2-2.4-1.9-1.5-1.9-2.1-0.7-2.6
Light reinforcement 10.00.10.30.4-0.10.20.2-0.2-0.2-0.40.2-0.4-0.20.20.0-0.50.00.1-0.0-0.20.0-0.2
Light reinforcement 20.71.13.20.1-0.8-0.1-0.20.20.2-1.81.00.4-1.61.10.90.61.61.60.91.10.91.5
Bone: marrow area1.43.012.01.90.1-0.0-0.10.10.1-2.23.30.6-1.73.51.30.60.50.81.71.83.02.0
Bone: maximum diameter1.63.010.13.11.31.61.8-1.8-1.8-1.83.2-1.1-1.63.1-0.6-1.0-0.7-0.2-0.30.52.00.4
Bone: maximum force0.40.83.51.20.60.10.1-0.1-0.1-0.61.70.40.21.90.30.3-0.5-0.30.81.11.71.1
Bone: maximum moment0.30.62.20.90.6-0.2-0.00.00.0-0.01.30.40.71.50.10.2-0.7-0.60.71.11.50.8
Mean time between licks in bursts0.30.73.90.6-0.80.00.5-0.5-0.51.00.40.30.30.50.20.5-2.0-1.90.40.81.10.0
Mean num. licks in bursts0.30.51.3-0.20.4-0.2-0.20.20.21.0-0.8-0.60.8-0.9-0.9-0.90.1-0.1-1.1-0.8-1.1-0.9
Cd content in liver0.30.41.20.40.0-0.5-0.30.30.30.20.40.40.60.60.50.8-1.1-0.90.90.41.10.1
Co content in liver0.10.10.30.40.30.30.2-0.2-0.2-0.20.2-0.1-0.20.3-0.0-0.4-0.10.0-0.2-0.30.0-0.5
Cu content in liver0.40.51.70.3-0.10.50.1-0.1-0.1-1.30.1-0.8-1.3-0.1-0.4-0.11.11.3-1.0-0.5-0.6-0.1
Fe content in liver0.81.03.71.30.90.50.4-0.4-0.4-1.41.80.3-0.81.90.20.5-0.10.20.91.21.51.3
K content in liver2.32.28.0-0.90.80.40.1-0.1-0.1-0.1-1.7-1.60.4-2.0-1.5-1.61.81.7-2.2-2.1-2.8-1.7
Mg content in liver0.70.72.2-1.00.1-0.4-0.60.60.60.6-1.5-0.30.8-1.5-0.5-0.40.50.3-1.0-0.7-1.4-0.9
Mn content in liver0.10.10.40.30.10.00.0-0.0-0.0-0.00.3-0.20.00.30.30.2-0.3-0.3-0.2-0.60.3-0.4
Na content in liver0.30.41.0-0.40.20.30.3-0.3-0.3-0.4-0.6-0.6-0.3-0.7-0.4-0.41.00.9-1.0-0.8-1.0-0.6
Rb content in liver0.91.06.0-0.6-0.70.4-0.10.10.1-1.3-0.5-0.1-1.4-0.7-0.40.02.42.4-0.5-0.0-1.10.6
Se content in liver0.30.41.30.20.3-0.5-0.50.50.5-0.30.40.50.10.71.01.1-0.5-0.40.70.50.90.5
Sr content in liver1.41.24.1-0.70.80.50.6-0.6-0.61.4-1.4-0.22.0-1.3-1.0-0.9-0.6-0.9-1.2-0.7-1.0-2.0
Zn content in liver2.12.35.71.31.11.91.3-1.3-1.3-1.4-0.2-2.2-1.2-0.5-1.8-1.80.30.7-2.4-2.3-1.7-1.7
Bone: minimum diameter2.74.915.74.02.62.12.5-2.5-2.5-1.63.8-1.6-1.03.7-1.3-1.5-1.8-1.2-0.40.42.30.1
Time in familiar zone, hab. session 10.50.51.1-0.4-0.7-0.9-1.01.01.00.4-0.30.70.1-0.10.91.0-0.4-0.40.40.80.40.6
Time in novel zone, hab. session 10.50.51.30.4-0.80.40.6-0.6-0.6-0.91.10.2-1.11.00.30.30.50.60.80.20.80.6
Total zone transitions, hab. session 12.02.811.50.92.40.10.8-0.8-0.82.2-0.3-0.73.10.1-0.9-1.1-3.4-3.3-1.0-0.80.2-1.8
Total locomotion distance, hab. session 12.02.811.70.42.20.00.7-0.7-0.72.4-0.9-0.73.0-0.7-0.9-1.2-3.4-3.4-1.2-0.7-0.4-1.6
Locomotion velocity, hab. session 13.14.415.70.42.70.10.8-0.8-0.83.1-1.3-1.03.8-1.0-1.3-1.8-3.9-4.0-1.8-1.2-0.8-2.3
Time in familiar zone, hab. session 20.20.21.10.0-1.0-0.6-0.40.40.40.8-0.10.1-0.0-0.20.30.6-0.3-0.40.30.40.3-0.3
Time in novel zone, hab. session 20.30.31.6-0.2-0.3-0.3-0.40.40.4-0.60.30.8-0.10.60.70.6-0.1-0.10.90.80.71.3
Total zone transitions, hab. session 21.82.412.30.31.6-1.1-0.40.40.42.2-0.20.53.00.30.20.0-3.5-3.40.10.91.2-0.5
Total locomotion distance, hab. session 22.02.514.20.11.2-1.0-0.10.10.12.6-0.50.32.9-0.00.1-0.1-3.7-3.8-0.20.70.9-0.9
Locomotion velocity, hab. session 22.02.714.40.11.4-1.0-0.10.10.12.7-0.50.33.1-0.10.1-0.1-3.8-3.8-0.30.60.8-0.9
Novel to familiar place preference ratio0.80.93.1-1.0-0.8-0.0-0.40.40.40.3-1.5-0.4-0.3-1.7-0.3-0.31.21.0-1.0-1.5-1.8-0.5
Novelty place preference1.11.24.2-1.3-1.3-0.3-0.80.80.80.6-1.9-0.2-0.2-2.0-0.1-0.11.20.9-0.9-1.4-1.8-0.6
Time in novel zone, NPP test0.70.82.8-1.0-1.2-0.2-0.60.60.60.4-1.5-0.2-0.4-1.7-0.10.01.00.8-0.8-1.2-1.5-0.5
Total zone transitions, NPP test1.01.58.81.22.1-0.30.2-0.2-0.20.60.60.11.51.1-0.2-0.1-3.0-2.6-0.20.51.30.0
Total locomotion distance, NPP test1.31.89.50.72.0-0.30.2-0.2-0.21.7-0.2-0.32.30.2-0.4-0.6-3.1-2.9-0.8-0.10.4-0.8
Locomotion velocity, NPP test1.11.56.70.31.8-0.6-0.10.10.11.8-0.5-0.12.5-0.1-0.3-0.6-2.6-2.6-0.8-0.20.2-0.7
Intraocular pressure0.20.30.8-0.7-0.7-0.6-0.60.60.6-0.00.10.8-0.30.10.80.50.90.70.90.40.30.1
Delta distance traveled before/after self-admin0.20.20.50.10.6-0.3-0.20.20.20.10.00.60.70.30.30.4-0.4-0.40.70.60.60.7
Delta ambulatory time before/after self-admin0.50.71.6-0.40.3-0.7-0.70.70.70.2-0.21.30.70.31.01.2-0.2-0.21.11.31.01.2
Parametrial fat weight0.82.06.60.7-0.7-0.6-0.30.30.3-0.31.61.1-0.61.71.61.6-1.6-1.32.12.12.61.9
Pavlov. Cond. lever latency1.31.65.91.7-0.40.60.1-0.1-0.1-2.32.1-0.0-2.42.10.50.60.71.10.60.41.51.5
Pavlov. Cond. magazine entry latency0.81.04.5-0.9-0.0-0.7-0.00.00.02.0-1.00.62.1-0.80.60.3-1.6-1.90.30.50.1-0.7
Pavlov. Cond. change in total contacts0.50.52.4-0.50.4-0.20.6-0.6-0.61.4-0.3-0.11.5-0.30.1-0.4-1.0-1.20.0-0.2-0.0-1.2
Pavlov. Cond. index score1.31.67.2-1.30.2-0.9-0.10.10.12.6-1.60.52.7-1.40.20.0-1.7-2.10.10.4-0.3-1.2
Pavlov. Cond. latency score1.41.78.1-1.50.2-0.9-0.20.20.22.7-1.90.42.8-1.70.0-0.2-1.4-1.8-0.10.2-0.7-1.3
Pavlov. Cond. lever contacts1.31.55.5-1.40.5-0.50.0-0.0-0.02.2-1.9-0.12.4-1.9-0.6-0.7-0.8-1.2-0.8-0.6-1.3-1.7
Pavlov. Cond. magazine entry number0.60.83.20.5-0.20.5-0.20.20.2-1.60.3-0.5-1.70.2-0.6-0.31.61.8-0.8-0.9-0.60.3
Pavlov. Cond. intertrial magazine entries1.11.45.01.3-0.20.20.3-0.3-0.3-1.32.10.5-1.42.20.80.9-0.6-0.31.31.02.11.0
Pavlov. Cond. lever-magazine prob. diff.1.21.57.0-1.10.2-0.9-0.10.10.12.5-1.30.52.6-1.10.30.1-1.9-2.20.30.6-0.0-1.0
Pavlov. Cond. response bias1.11.36.3-1.30.1-0.70.0-0.0-0.02.4-1.40.32.5-1.30.2-0.1-1.4-1.80.10.2-0.4-1.2
Pavlov. Cond. lever latency0.91.24.40.0-0.31.20.8-0.8-0.8-1.3-0.0-0.7-1.9-0.5-1.1-1.22.12.1-0.8-0.4-1.30.1
Pavlov. Cond. magazine entry latency0.10.20.60.20.30.00.1-0.1-0.10.50.1-0.30.80.1-0.2-0.4-0.6-0.7-0.4-0.7-0.1-0.3
Pavlov. Cond. change in total contacts1.11.76.42.02.30.50.7-0.7-0.70.01.6-0.51.22.0-0.1-0.3-2.5-2.1-0.1-0.31.5-0.3
Pavlov. Cond. index score0.40.52.40.81.00.10.3-0.3-0.30.40.6-0.31.20.90.2-0.0-1.5-1.4-0.1-0.60.7-0.4
Pavlov. Cond. latency score0.30.41.90.60.8-0.10.1-0.1-0.10.50.5-0.11.20.70.30.1-1.4-1.30.0-0.50.6-0.3
Pavlov. Cond. lever contacts0.91.35.60.30.4-1.0-0.50.50.51.20.40.61.80.91.11.1-2.4-2.30.80.51.6-0.1
Pavlov. Cond. magazine entry number0.50.62.3-1.1-0.7-0.3-0.70.70.7-0.2-1.10.4-0.6-1.2-0.10.41.51.40.00.3-0.90.2
Pavlov. Cond. intertrial magazine entries0.30.42.2-0.5-1.5-0.5-0.70.70.70.2-0.90.3-0.9-0.90.30.9-0.1-0.10.0-0.0-0.2-0.2
Pavlov. Cond. lever-magazine prob. diff.0.50.62.20.91.20.30.5-0.5-0.50.50.6-0.51.20.8-0.1-0.4-1.5-1.4-0.3-0.80.4-0.6
Pavlov. Cond. response bias0.81.05.50.70.7-0.40.0-0.0-0.01.00.70.11.61.00.50.5-2.3-2.20.40.21.3-0.2
Time in closed arm before self-admin0.20.30.90.50.60.60.4-0.4-0.4-0.20.0-0.6-0.2-0.1-0.7-0.9-0.5-0.3-0.6-0.7-0.4-0.7
Time in closed arm after self-admin0.40.41.50.6-0.80.60.5-0.5-0.5-0.71.2-0.1-1.21.00.2-0.30.30.3-0.00.00.60.9
Time in open arm before self-admin0.10.20.5-0.1-0.7-0.4-0.30.30.30.6-0.00.30.60.10.40.2-0.2-0.40.20.50.40.6
Time in open arm after self-admin1.61.73.6-1.7-1.1-1.9-1.91.91.91.0-1.21.41.4-0.81.31.50.30.01.31.00.40.3
Bone: periosteal estimation1.32.711.52.61.00.80.7-0.7-0.7-2.03.3-0.1-1.53.40.2-0.2-0.20.20.81.52.61.5
Bone: periosteal perimeter1.12.07.62.41.11.11.2-1.2-1.2-1.42.7-0.3-1.12.8-0.2-0.4-0.6-0.20.20.92.01.1
Bone: post-yield work0.20.41.20.80.20.40.4-0.4-0.4-0.91.10.0-0.61.10.20.30.20.30.40.60.80.8
Progressive ratio test 1 active lever presses4.85.912.73.12.83.63.3-3.3-3.3-2.62.0-2.8-1.91.6-2.5-2.80.51.1-2.0-1.7-0.6-1.6
Progressive ratio test 1 breakpoint4.96.012.83.02.93.63.3-3.3-3.3-2.52.0-2.8-1.91.5-2.5-2.80.51.1-2.1-1.8-0.7-1.7
Progressive ratio test 1 inactive lever presses0.10.20.70.3-0.00.60.4-0.4-0.4-0.50.1-0.5-0.60.0-0.3-0.50.80.8-0.1-0.0-0.30.0
Progressive ratio test 2 active lever presses1.61.94.41.21.42.12.1-2.1-2.1-0.20.2-1.7-0.4-0.1-1.8-1.5-0.3-0.1-1.4-1.2-1.0-1.4
Progressive ratio test 2 breakpoint1.72.04.51.21.32.12.1-2.1-2.1-0.20.2-1.8-0.4-0.2-1.8-1.6-0.3-0.1-1.4-1.3-1.1-1.5
Progressive ratio test 2 inactive lever presses0.10.21.0-0.20.20.30.1-0.1-0.10.1-0.6-0.40.0-0.8-0.6-0.50.30.3-0.4-0.3-1.0-0.3
Incentive Sensitization - Responses0.71.02.20.50.61.11.3-1.3-1.30.7-0.3-1.30.3-0.7-1.5-1.2-0.5-0.5-1.2-1.1-1.2-1.2
Incentive Sensitization - Breakpoint0.60.81.80.30.40.91.0-1.0-1.00.8-0.4-1.20.4-0.8-1.3-1.1-0.4-0.4-1.1-1.0-1.2-1.1
Sum of active levers in priming session hrs 5-61.31.26.0-0.01.00.00.5-0.5-0.51.5-1.1-0.81.1-1.1-0.8-0.4-1.5-1.5-1.1-1.1-0.8-2.4
Progressive ratio0.81.33.7-1.3-0.6-1.3-1.51.51.50.6-0.41.90.5-0.21.10.80.30.11.31.20.61.9
Food seeking constrained by brief footshock1.61.93.71.61.91.91.7-1.7-1.7-1.10.9-1.8-1.20.4-1.8-1.60.00.4-1.3-1.4-0.9-1.0
Seeking ratio, punishment vs. effort1.01.54.01.41.11.61.5-1.5-1.5-0.70.5-2.0-0.80.2-1.5-1.0-0.5-0.2-1.4-1.2-0.7-1.6
Retroperitoneal fat weight1.25.211.33.23.13.13.4-3.4-3.4-1.02.3-2.4-0.41.9-2.0-2.6-1.7-1.1-1.2-1.10.5-1.5
Reaction time number correct0.10.31.1-0.00.1-0.3-0.10.10.10.90.60.21.10.50.1-0.2-0.2-0.40.90.80.7-0.1
Reaction time mean minus median0.41.03.7-1.3-1.9-1.2-1.11.11.11.0-1.50.80.5-1.20.70.8-0.0-0.20.20.4-0.40.3
Reaction time mean minus median AUC0.41.03.6-1.3-1.9-0.9-0.70.70.71.3-1.90.50.8-1.60.40.8-0.3-0.5-0.20.2-0.7-0.3
Reaction time num false alarms0.50.83.1-1.2-1.8-1.0-1.01.01.00.3-1.10.4-0.3-1.20.40.71.00.90.20.3-0.60.4
Reaction time num false alarms AUC0.71.24.3-1.5-2.1-1.3-1.31.31.30.5-1.20.8-0.1-1.20.81.20.80.60.60.8-0.30.7
Reaction time trials correct on left0.10.31.1-0.00.1-0.3-0.10.10.10.90.60.21.10.50.1-0.2-0.2-0.40.90.80.7-0.1
Reaction time trials on left0.20.31.2-0.1-0.1-0.4-0.20.20.21.00.50.31.10.40.1-0.1-0.2-0.40.90.90.7-0.0
Reaction time mean0.20.31.60.5-0.7-0.20.0-0.0-0.00.10.50.3-0.10.70.40.3-1.3-1.10.40.61.00.2
Reaction time mean AUC0.10.21.00.7-0.50.20.4-0.4-0.4-0.10.5-0.0-0.40.60.10.1-1.0-0.80.10.40.70.1
Median of all reaction times0.40.61.91.20.00.40.6-0.6-0.6-0.41.2-0.1-0.51.30.1-0.0-1.4-1.10.30.51.20.1
Reaction time omissions2.94.315.6-2.1-3.9-2.8-3.03.03.01.9-1.22.00.5-1.02.01.90.2-0.31.51.80.71.4
Reaction time false alarm rate0.71.03.4-1.3-1.9-1.1-1.21.21.2-0.1-1.20.7-0.7-1.10.81.10.90.80.10.4-0.50.7
Reaction time premature initiation rate0.50.73.00.20.0-0.7-0.10.10.11.20.50.31.50.80.6-0.1-1.7-1.70.60.81.3-0.3
Reaction time premature initiations0.40.73.50.30.2-0.50.1-0.1-0.11.40.5-0.01.90.60.1-0.6-1.4-1.60.60.61.1-0.7
Std. dev. reaction times0.71.25.5-1.2-2.3-1.4-1.31.31.31.2-1.41.00.7-1.10.81.0-0.5-0.70.60.8-0.00.3
Reaction time trials completed0.20.31.2-0.1-0.1-0.4-0.20.20.21.00.50.31.10.40.1-0.1-0.2-0.40.90.90.7-0.0
Reaction time trials AUC0.20.31.20.10.2-0.20.0-0.0-0.00.90.70.21.10.60.0-0.2-0.2-0.50.90.90.8-0.0
Run reversals in cocaine runway, females0.20.21.10.51.10.40.3-0.3-0.30.00.2-0.20.30.2-0.7-0.80.10.1-0.30.1-0.20.1
Run reversals in cocaine runway, males0.10.10.8-0.1-0.1-0.1-0.00.00.00.3-0.4-0.40.3-0.3-0.10.1-0.5-0.5-0.3-0.4-0.3-0.9
Latency to leave start box in cocaine runway0.10.20.60.2-0.40.10.5-0.5-0.50.6-0.0-0.40.1-0.1-0.2-0.2-0.7-0.8-0.2-0.2-0.0-0.6
Latency to leave start box in cocaine runway, F0.60.71.9-0.5-0.7-1.0-0.60.60.60.9-0.50.80.4-0.11.21.4-1.3-1.40.70.40.80.2
Latency to leave start box in cocaine runway, M1.61.54.40.70.11.41.4-1.4-1.4-0.30.2-1.8-0.2-0.4-1.9-2.10.90.9-1.4-1.1-1.4-1.4
Std. dev. time between licks in bursts1.31.76.1-0.3-0.9-1.2-0.90.90.91.4-0.41.51.40.11.21.6-2.5-2.50.91.41.50.4
Total sessions with >9 infusions2.22.75.72.12.02.42.4-2.4-2.4-1.61.7-1.7-1.51.3-1.4-1.50.20.6-1.0-0.90.0-1.1
Short access day 1 total inactive lever presses0.30.41.60.4-0.50.0-0.00.00.0-1.00.80.2-1.30.70.30.20.60.80.50.30.51.1
Short access day 10 total inactive lever presses2.25.411.1-3.3-3.3-3.1-3.23.23.22.3-2.92.41.5-2.52.12.10.2-0.41.31.2-0.61.5
Short access day 1 total infusions0.30.42.60.5-0.00.60.5-0.5-0.5-1.01.00.3-1.60.90.40.20.50.60.50.30.60.4
Short access day 10 total infusions2.02.56.72.42.02.21.8-1.8-1.8-2.61.9-1.4-2.31.6-1.1-0.90.20.9-0.7-0.60.2-0.1
Short access total infusions1.01.33.11.51.31.71.5-1.5-1.5-1.61.4-0.7-1.81.2-0.6-0.70.40.7-0.3-0.20.3-0.2
Short access day 1 locomotion0.50.61.40.70.31.00.8-0.8-0.8-0.60.4-1.2-0.70.1-0.9-1.10.70.8-0.8-0.8-0.5-1.0
Short access day 10 total locomotion0.20.31.30.20.2-0.2-0.50.50.5-1.10.30.5-0.40.60.60.90.10.30.70.60.60.6
Short access total locomotion1.11.32.41.01.41.51.2-1.2-1.2-1.30.3-1.5-0.80.0-1.4-1.30.81.0-1.3-1.3-1.0-1.3
One hour access (0.3 mA shock)5.76.614.23.03.83.73.7-3.7-3.7-1.31.1-2.9-0.70.8-3.1-3.0-0.9-0.2-2.3-2.1-1.2-2.3
Compulsive drug intake0.50.62.5-0.7-0.10.1-0.10.10.10.6-0.7-0.51.0-0.9-0.7-1.61.20.9-0.5-0.5-1.3-0.8
One hour access (shock baseline)2.74.19.62.53.13.02.9-2.9-2.9-1.20.8-2.2-1.10.6-2.3-1.6-1.1-0.5-1.9-1.6-0.7-1.5
Social response proportion0.91.13.11.81.00.81.0-1.0-1.0-0.61.7-0.6-0.11.7-0.5-0.5-1.4-1.1-0.00.61.30.1
Social responses0.91.15.40.80.9-0.00.5-0.5-0.51.50.3-0.51.80.4-0.7-0.6-2.3-2.3-0.40.30.7-1.0
Social time0.60.92.10.71.00.91.3-1.3-1.30.40.4-1.20.70.1-1.3-1.1-0.6-0.6-0.8-0.5-0.4-1.5
Soleus weight0.41.14.01.40.30.40.7-0.7-0.7-0.61.90.3-0.42.00.30.4-0.7-0.51.01.72.00.7
Bone: stiffness1.93.010.12.92.41.41.8-1.8-1.8-1.33.0-0.80.03.2-0.3-0.6-1.6-1.10.30.82.30.6
Tibialis anterior weight0.41.46.11.0-0.60.00.4-0.4-0.40.11.80.7-0.21.80.60.9-0.8-0.71.72.52.21.4
Time to tail flick, vehicle, before self-admin3.03.17.01.20.91.92.0-2.0-2.0-0.10.2-2.50.1-0.2-2.3-2.6-0.6-0.6-2.4-2.7-1.5-2.6
Time to tail flick, vehicle, after self-admin1.01.33.2-1.4-0.3-1.4-1.01.01.01.6-1.31.41.4-1.01.01.8-1.3-1.40.80.90.40.2
Time to tail flick, test, before self-admin0.70.72.40.90.20.30.1-0.1-0.1-1.51.6-0.0-0.61.50.1-0.40.81.00.50.80.91.0
Time to tail flick, test, after self-admin0.10.10.50.30.4-0.1-0.10.10.1-0.10.70.10.60.7-0.1-0.4-0.4-0.50.20.10.50.2
Delta time to tail flick, vehicle, before/after SA3.33.29.3-1.8-0.8-2.2-1.91.91.91.5-1.02.60.9-0.52.23.0-0.7-0.92.12.41.41.7
Delta time to tail flick, test, before/after SA0.60.61.9-0.90.3-0.4-0.40.40.41.3-1.40.21.2-1.3-0.20.1-0.6-0.9-0.3-0.6-0.8-0.7
Tibia length5.314.636.36.04.95.04.8-4.8-4.8-3.33.9-4.5-2.23.4-4.1-4.2-2.1-0.8-3.3-2.70.1-1.9
Ambulatory time before self-admin0.10.10.50.30.30.60.7-0.7-0.7-0.10.2-0.3-0.20.1-0.4-0.6-0.1-0.0-0.1-0.3-0.2-0.2
Ambulatory time after self-admin0.60.71.90.30.8-0.00.1-0.1-0.10.20.51.10.50.90.70.5-1.0-0.91.31.31.31.4
Bone: tissue strength0.70.72.90.91.70.30.6-0.6-0.60.50.8-0.31.41.0-0.4-0.3-1.4-1.30.00.10.9-0.5
Total heroin consumption1.61.93.5-0.6-1.1-1.8-1.41.41.41.40.11.70.80.41.81.4-1.5-1.61.81.51.90.5
Bone: trabecular number0.20.31.5-1.00.2-0.2-0.20.20.20.4-0.60.20.6-0.7-0.2-0.41.20.90.5-0.0-0.7-0.1
Bone: trabecular spacing0.30.41.5-0.7-1.2-0.6-0.90.90.90.7-1.00.30.2-1.00.10.1-0.0-0.2-0.6-0.1-0.60.0
Bone: trabecular thickness0.20.20.50.30.60.60.7-0.7-0.7-0.2-0.0-0.7-0.4-0.1-0.5-0.30.40.5-0.2-0.5-0.5-0.4
Bone: trabecular tissue density0.10.11.40.01.20.10.2-0.2-0.20.0-0.2-0.20.80.10.2-0.2-0.1-0.10.3-0.2-0.1-0.1
Water consumed over 24 hours2.43.26.62.11.22.42.0-2.0-2.0-2.11.4-2.6-2.40.7-1.9-1.61.31.7-1.7-1.8-0.9-0.9
Number of responses in last shaping day0.10.10.3-0.10.2-0.1-0.10.10.10.5-0.2-0.00.3-0.4-0.4-0.3-0.3-0.4-0.2-0.2-0.3-0.5