Hub : Genes

Cep83

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 PL isoform ratio XM_063264041.1 0.02 0.01 4.2e-03 0.01 0.01 0.01 0 2.3e-02 1.7e-02 3.9e-02 7.7e-02
2 Adipose intron excision ratio chr7_31209896_31212408 0.04 0.02 4.9e-04 0.03 0.03 0.01 0.03 5.1e-04 7.4e-04 9.3e-03 3.3e-04
3 Adipose alternative polyA XM_063264042.1 0.02 0.01 2.6e-03 0.01 0.02 0.01 0.01 1.2e-02 5.0e-03 1.2e-02 3.9e-02
4 PL isoform ratio XM_063264042.1 0.05 0.03 2.4e-03 0 0.01 0 0 1.8e-01 8.0e-03 7.4e-02 2.0e-01
5 IC alternative polyA XM_063264042.1 0.2 0.11 9.8e-03 -0 0.03 0.04 0.02 5.3e-01 1.9e-02 7.8e-03 6.5e-02
6 Adipose alternative TSS XM_063264028.1 0.08 0.05 6.4e-03 0.01 0.02 0.01 0.01 4.7e-02 6.4e-03 7.0e-03 2.2e-02
7 Adipose alternative TSS XM_063264028.1 0.07 0.05 6.7e-03 0.01 0.01 0.01 0.01 4.9e-02 9.5e-03 3.3e-02 3.8e-02
8 Liver gene expression Cep83 0.06 0.03 4.3e-04 0.03 0.02 0.03 0.03 7.9e-04 1.2e-03 6.2e-04 8.5e-04
9 IL gene expression Cep83 0.16 0.09 6.8e-03 0.15 0.07 0.05 0.08 2.3e-04 9.1e-03 2.4e-02 6.7e-03
10 IC gene expression Cep83 0.15 0.07 8.5e-05 0.09 0.08 0.09 0.09 1.4e-04 2.3e-04 1.8e-04 9.6e-05
11 Brain gene expression Cep83 0.14 0.05 4.8e-14 0.18 0.14 0.16 0.17 5.7e-17 3.2e-13 1.7e-14 1.3e-15
12 pVTA gene expression Cep83 0.08 0.04 2.9e-05 0.08 0.06 0.07 0.08 4.6e-07 7.2e-06 1.4e-06 1.1e-06
13 BLA gene expression Cep83 0.08 0.05 5.1e-03 0.03 0.03 0.03 0.03 1.4e-02 1.3e-02 1.1e-02 6.9e-03
14 PL gene expression Cep83 0.09 0.04 1.2e-09 0.08 0.09 0.08 0.08 1.9e-09 1.4e-09 3.1e-09 2.6e-09
15 NAcc gene expression Cep83 0.05 0.02 3.2e-05 0.01 0.02 0.01 0.02 2.3e-03 8.4e-04 1.8e-03 8.0e-04

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15
Bone: apparent density0.10.21.0-0.20.40.40.8-0.9-0.2-0.40.21.00.40.20.10.10.20.0
Area under the delay curve1.82.17.8-0.2-0.8-0.4-0.90.31.61.6-2.8-0.7-1.2-1.9-2.0-1.4-1.6-1.7
BMI with tail1.55.213.2-3.6-2.72.83.0-3.53.53.30.1-0.3-0.2-0.2-0.6-0.6-1.4-1.7
BMI without tail2.37.120.1-4.5-3.34.13.9-4.22.42.11.31.81.91.71.41.60.70.3
Body weight5.925.975.2-8.7-7.37.66.9-7.45.04.52.63.73.32.92.62.71.1-0.1
Weight adjusted by age0.40.62.20.60.3-0.3-0.10.6-1.1-1.11.00.40.50.51.50.50.91.1
Bone surface0.30.51.4-1.1-0.80.90.9-1.20.90.8-0.30.4-0.1-0.1-0.0-0.1-0.3-0.6
Bone volume0.20.41.9-1.0-0.50.91.1-1.40.70.5-0.10.70.1-0.0-0.0-0.1-0.2-0.4
Breakpoint value in progressive ratio session1.41.72.81.41.2-1.7-0.80.90.60.7-1.0-1.6-1.5-1.6-1.6-1.3-1.5-1.2
Number of licking bursts0.61.04.7-1.1-0.40.81.6-2.21.71.50.40.10.1-0.00.1-0.1-0.7-0.8
Context. condit. distance diff. score0.20.21.4-0.6-1.20.3-0.61.00.40.5-0.2-0.2-0.10.0-0.20.10.0-0.3
Locomotion velocity, session 10.50.51.91.41.1-1.1-0.71.0-1.0-0.90.0-0.1-0.2-0.20.1-0.60.20.1
Locomotion distance, session 10.10.10.40.0-0.1-0.20.40.00.60.60.1-0.3-0.3-0.00.0-0.5-0.4-0.2
Locomotion velocity, session 20.40.51.90.91.0-0.4-0.60.3-1.4-1.40.30.10.20.20.40.40.50.4
Locomotion distance, session 20.20.31.0-0.8-0.50.60.9-1.00.90.90.3-0.3-0.20.20.1-0.1-0.4-0.3
Locomotion velocity, session 30.70.83.70.90.4-0.5-1.01.6-1.9-1.7-0.10.3-0.1-0.10.1-0.20.50.1
Locomotion distance, session 30.10.20.4-0.5-0.70.2-0.10.30.40.5-0.3-0.3-0.4-0.3-0.3-0.2-0.5-0.6
Stereotopy head waving bouts, day 30.30.31.61.11.3-0.7-0.00.2-0.7-0.8-0.20.20.0-0.1-0.4-0.30.20.3
Stereotopy head waving duration, day 30.50.62.40.91.0-0.4-0.10.5-1.5-1.6-0.10.70.40.0-0.40.00.70.6
Locomotion velocity, session 70.10.10.70.10.3-0.2-0.30.30.30.30.9-0.5-0.10.30.30.0-0.20.1
Locomotion distance, session 70.10.21.20.10.1-0.3-0.50.6-0.00.10.2-1.1-0.5-0.2-0.10.0-0.40.1
Stereotopy head waving bouts, day 70.60.71.50.51.2-0.00.5-0.6-1.2-1.21.21.20.90.60.8-0.10.70.5
Stereotopy head waving duration, day 70.40.51.50.51.20.00.6-0.7-1.0-1.00.71.20.70.30.3-0.30.40.2
Locomotion velocity, session 80.40.51.10.0-0.30.2-0.30.6-1.0-1.00.50.80.80.70.90.71.00.9
Locomotion distance, session 80.81.15.4-1.9-2.31.30.7-0.11.61.60.2-0.00.10.40.20.2-0.1-0.4
Degree of sensitization distance0.10.10.60.50.5-0.4-0.30.2-0.2-0.2-0.2-0.8-0.3-0.4-0.20.0-0.20.2
Degree of sensitization stereotypy0.50.52.20.71.5-0.20.2-0.4-1.1-1.10.90.70.40.10.4-0.60.2-0.0
Conditioned locomotion0.10.10.30.20.5-0.2-0.2-0.00.40.4-0.1-0.5-0.3-0.2-0.5-0.4-0.3-0.3
Cocaine response after cond. corrected0.20.30.8-0.8-0.70.90.4-0.80.20.1-0.90.40.3-0.1-0.20.50.20.1
Cocaine response after cond. not corrected0.30.41.4-1.0-1.20.90.5-0.70.50.4-0.80.40.3-0.10.10.60.30.0
Cocaine response before conditioning0.10.10.70.0-0.6-0.3-0.10.60.30.40.4-0.2-0.00.20.80.00.20.0
Saline control response0.81.01.8-0.7-0.51.10.6-0.8-1.2-1.21.41.01.01.11.31.20.90.8
Bone: connectivity density0.30.41.50.50.7-0.00.2-0.0-1.1-1.20.11.10.60.30.20.60.70.6
Bone: cortical apparent density0.10.20.8-0.2-0.3-0.00.10.40.80.80.9-0.10.30.6-0.2-0.10.2-0.2
Bone: cortical area0.81.33.6-1.9-1.91.51.5-1.41.61.5-0.40.70.30.10.10.2-0.2-0.0
Bone: cortical porosity0.30.31.3-0.10.30.5-0.1-0.4-1.0-1.1-0.60.40.30.20.00.60.50.2
Bone: cortical porosity0.10.10.8-0.20.10.40.0-0.4-0.5-0.6-0.90.30.10.0-0.30.30.3-0.0
Bone: cortical thickness0.30.61.6-1.1-1.31.10.7-0.40.0-0.1-0.31.10.70.60.30.70.70.8
Bone: cortical thickness0.30.31.30.70.7-0.6-0.40.3-0.4-0.4-1.1-0.1-0.3-0.5-0.9-0.5-0.1-0.2
Bone: cortical tissue density0.10.20.9-0.2-0.4-0.00.10.50.70.70.9-0.00.40.6-0.1-0.10.3-0.1
Condit. Reinf. active minus inactive responses0.80.93.01.51.1-1.5-1.31.7-0.8-0.6-0.2-0.6-0.7-0.2-0.1-0.9-0.2-0.3
Condit. Reinf. active-inactive response ratio0.60.71.41.21.0-1.2-1.00.9-0.3-0.2-0.4-0.9-0.9-0.6-0.2-1.0-0.6-0.8
Condit. Reinf. active responses1.01.34.22.01.8-1.8-1.41.6-1.2-1.1-0.3-0.5-0.7-0.2-0.5-0.8-0.20.0
Condit. Reinf. inactive responses0.60.72.91.61.7-1.3-0.80.7-0.9-0.9-0.4-0.2-0.4-0.2-0.7-0.4-0.20.4
Incentive salience index mean0.20.30.90.80.5-0.7-0.31.0-0.5-0.50.50.0-0.00.50.6-0.30.30.3
Condit. Reinf. lever presses0.30.41.4-0.2-0.10.20.7-0.10.10.01.00.60.51.01.20.20.60.7
Condit. Reinf. active minus inactive responses0.30.41.61.01.3-0.8-0.50.4-0.9-0.80.7-0.5-0.3-0.20.2-0.5-0.20.1
Condit. Reinf. active-inactive response ratio0.40.52.90.40.60.1-0.20.3-1.7-1.60.30.20.30.20.10.30.60.7
Condit. Reinf. active responses0.30.41.20.91.1-0.9-0.40.20.00.10.9-0.8-0.6-0.20.3-0.7-0.7-0.2
Condit. Reinf. inactive responses0.91.22.61.10.8-1.6-0.90.61.41.5-0.1-1.3-1.2-0.8-0.1-1.3-1.2-0.9
Condit. Reinf. lever presses0.30.52.30.81.5-0.50.2-0.5-0.4-0.41.5-0.5-0.10.40.6-0.1-0.20.4
Condit. Reinf. lever reinforcers received0.40.51.10.71.0-0.9-0.30.20.40.50.8-1.0-0.8-0.30.1-0.9-0.9-0.4
Conditioned reinforcement - actives0.81.43.9-0.5-0.50.80.9-0.7-0.7-0.81.42.01.41.11.81.11.41.1
Conditioned reinforcement - inactives0.10.10.5-0.1-0.10.20.6-0.70.20.10.40.50.40.30.5-0.10.40.2
Conditioned locomotion0.60.71.7-0.6-1.00.80.6-0.3-0.5-0.50.91.31.00.91.10.91.00.8
Patch foraging indifference point 0 sec0.10.30.7-0.20.20.30.4-0.90.20.10.50.80.60.40.80.60.30.5
Patch foraging indifference point AUC0.81.11.9-0.8-0.21.11.3-1.3-0.8-0.91.30.91.11.31.40.81.01.2
Delay disc. indifference point, 0s delay0.60.61.30.30.8-0.40.5-0.81.11.0-0.50.1-0.3-0.9-1.0-1.0-0.9-1.0
Delay disc. indifference point, 16s delay3.23.58.6-0.7-1.3-0.1-0.4-0.22.62.6-2.9-1.0-1.5-2.3-2.6-1.7-2.2-2.4
Delay disc. indifference point, 2s delay0.30.31.3-0.5-1.10.2-0.10.50.70.7-0.90.2-0.0-0.4-0.9-0.1-0.3-0.3
Delay disc. indifference point, 24s delay1.51.76.3-0.9-2.00.2-0.40.71.61.7-2.5-0.2-0.7-1.5-1.6-0.8-0.9-1.2
Delay disc. indifference point, 4s delay0.20.21.60.1-0.3-0.1-0.60.4-0.0-0.0-1.20.30.0-0.6-0.4-0.2-0.0-0.2
Delay disc. indifference point, 8s delay1.82.29.50.3-0.2-0.7-1.30.41.01.1-3.1-1.0-1.5-2.0-1.9-1.6-1.5-1.7
Indifference point function ln k0.50.81.90.2-0.3-0.6-0.60.61.31.4-0.9-1.1-1.0-0.8-1.0-0.8-0.9-1.0
Indifference point function log k0.50.81.90.2-0.3-0.6-0.60.61.31.4-0.9-1.1-1.0-0.8-1.0-0.8-0.9-1.0
Patch foraging total patch changes 0 sec0.10.30.9-0.20.30.30.5-0.90.1-0.00.50.90.60.40.70.60.40.5
Patch foraging total patch changes 12 sec2.32.94.3-1.3-0.31.72.0-2.0-0.7-1.01.92.02.01.81.92.11.62.0
Patch foraging total patch changes 18 sec2.23.46.3-1.1-0.41.61.8-1.8-0.6-0.82.42.22.32.22.51.91.92.2
Patch foraging total patch changes 24 sec1.42.54.2-1.5-1.01.81.5-1.5-0.7-0.91.52.12.01.71.61.91.61.7
Patch foraging total patch changes 6 sec0.30.42.4-0.40.30.60.9-1.50.1-0.00.70.60.50.50.70.40.20.6
Patch foraging time to switch 0 sec0.00.00.10.10.2-0.0-0.30.10.00.00.20.10.20.10.20.00.10.1
Patch foraging water rate 0 sec0.81.64.7-2.1-2.21.51.7-1.32.02.00.20.30.20.4-0.10.3-0.2-0.6
Patch foraging water rate 12 sec1.42.97.3-2.4-1.42.62.6-2.70.30.11.61.71.61.51.01.50.80.9
Patch foraging water rate 18 sec0.20.31.0-0.5-0.00.50.7-0.70.20.20.0-0.2-0.5-0.5-0.8-0.4-0.7-1.0
Patch foraging water rate 24 sec1.72.47.1-2.6-2.71.91.9-1.12.52.40.30.50.40.4-0.40.4-0.1-0.5
Patch foraging water rate 6 sec3.24.711.8-3.4-2.62.83.2-3.23.02.81.41.11.10.90.40.9-0.1-0.4
Seeking ratio, delayed vs. immediate footshock0.10.10.30.10.1-0.10.4-0.40.30.2-0.40.00.1-0.0-0.30.50.00.4
Distance traveled before self-admin0.10.20.5-0.5-0.70.40.60.20.50.5-0.2-0.0-0.1-0.2-0.7-0.3-0.4-0.4
Distance traveled after self-admin1.31.63.10.30.0-0.8-0.60.81.31.4-1.3-1.3-1.4-1.5-1.8-1.6-1.6-1.5
Extensor digitorum longus weight0.10.61.5-1.2-0.71.10.8-1.20.50.4-1.10.1-0.1-0.2-1.00.0-0.3-0.6
Bone: elastic displacement2.93.37.52.61.9-2.2-2.62.7-2.2-2.0-2.1-1.1-1.3-1.3-1.3-0.8-0.3-0.3
Bone: elastic work1.82.45.72.01.1-1.6-2.22.4-2.1-2.0-2.3-0.7-0.9-1.1-1.2-0.10.00.3
Bone: endosteal estimation1.94.210.9-0.8-0.1-0.10.3-1.73.33.3-1.3-2.2-2.1-2.1-1.6-2.0-2.8-2.7
Bone: endosteal perimeter1.94.016.3-2.5-2.51.31.3-2.04.03.9-0.9-0.8-0.8-0.9-0.5-0.7-1.6-1.6
Epididymis fat weight1.24.210.7-3.3-2.92.43.0-2.53.23.11.30.50.60.60.30.2-0.5-1.0
Delta time in closed arm before/after self-admin0.20.10.8-0.7-0.90.60.3-0.40.10.20.2-0.1-0.00.10.4-0.20.0-0.1
Delta time in open arm before/after self-admin1.41.47.71.92.8-1.5-0.90.3-0.6-0.7-0.6-0.8-0.9-0.8-1.2-0.9-0.9-0.2
Diff in mean of infusions in LGA sessions0.30.41.21.00.9-0.7-0.70.9-1.1-1.0-0.0-0.4-0.2-0.2-0.1-0.00.10.3
Delay discount exponential model param1.51.77.30.31.00.20.9-0.4-1.3-1.42.70.51.01.71.81.21.31.5
Extinction: sum of active levers before priming0.30.30.70.30.1-0.4-0.30.6-0.10.0-0.7-0.8-0.7-0.5-0.8-0.5-0.6-0.7
Active lever presses in extinction session 60.50.51.50.30.3-0.5-0.20.50.40.5-0.6-1.2-0.9-0.8-1.2-0.6-0.9-0.7
Bone: final force0.81.32.7-1.1-0.80.70.7-1.21.61.6-1.2-0.6-0.9-1.0-1.2-0.9-1.3-1.2
Bone: final moment0.61.01.9-1.1-0.80.70.8-1.21.41.3-1.2-0.4-0.7-0.9-1.1-0.6-1.1-1.0
Food consumed during 24 hour testing period0.60.82.4-0.8-0.60.91.2-0.90.10.01.50.70.91.11.00.70.70.7
Glucose0.00.10.4-0.00.30.10.7-0.40.10.10.50.30.10.0-0.2-0.1-0.10.0
Heart weight0.81.22.8-1.5-1.31.01.0-1.41.71.6-0.8-0.3-0.5-0.7-0.6-0.3-1.0-1.2
Delay discount hyperbolic model param1.31.46.50.41.10.10.9-0.4-1.3-1.32.50.40.81.51.50.91.11.2
Intermittent access intake day 1-15 change1.02.13.2-1.3-1.21.51.6-0.8-0.4-0.51.51.61.81.81.61.71.71.7
Intermittent access intake escalation0.91.92.9-1.3-1.31.41.6-0.8-0.1-0.21.41.51.71.71.41.61.51.6
Intermittent access intake escalation 20.80.91.8-0.8-0.81.00.80.0-0.5-0.50.81.01.21.30.81.31.31.1
Intermitt. access day 1 inactive lever presses0.31.23.61.91.9-1.5-1.40.7-1.2-1.2-0.7-0.6-0.7-0.7-0.7-0.8-0.4-0.2
Intermitt. access day 15 inactive lever presses0.20.41.20.80.4-0.7-0.71.1-0.8-0.7-0.5-0.2-0.3-0.4-0.4-0.70.0-0.3
Intermitt. access escalation Index0.20.31.70.80.3-0.8-0.91.3-0.7-0.6-0.0-0.2-0.3-0.1-0.1-0.10.00.2
Intermittent access day 1 total infusions0.40.62.3-1.5-1.51.40.4-0.70.30.20.30.90.60.40.50.40.4-0.0
Intermittent access day 15 total infusions1.21.84.0-2.0-1.92.01.4-1.00.30.20.91.81.51.31.01.31.20.8
Intermittent access terminal intake (last 3 days)0.81.13.9-1.8-2.01.70.9-0.60.40.40.41.11.00.90.40.80.90.2
Intermittent access total infusions0.70.83.1-1.6-1.81.40.6-0.60.50.50.30.90.70.60.40.60.50.1
Intermittent access day 1 locomotion0.10.20.7-0.7-0.50.8-0.1-0.5-0.2-0.2-0.00.50.40.20.20.10.3-0.2
Intermittent access day 15 total locomotion0.81.43.0-0.7-1.01.00.50.0-0.9-1.01.01.71.61.41.31.21.71.3
Intermittent access total locomotion0.40.51.3-1.1-1.11.20.3-0.6-0.1-0.20.40.90.80.60.40.60.70.2
Intermittent access standard deviation1.02.13.8-1.8-1.62.01.6-1.2-0.1-0.21.21.61.71.71.11.81.51.3
Left kidney weight1.98.722.6-4.8-4.64.44.1-3.31.71.42.12.62.42.42.32.01.61.0
Right kidney weight1.57.020.9-4.6-4.13.83.8-3.62.92.71.41.41.21.31.11.20.2-0.3
Cocaine induced anxiety1.72.54.12.01.9-2.0-1.81.3-0.00.1-1.5-1.6-1.7-1.7-1.7-1.8-1.4-1.4
Post-drug Anxiety1.41.53.41.61.3-1.6-1.51.9-0.8-0.6-1.0-1.2-1.2-1.1-1.3-1.0-0.7-0.7
Baseline Anxiety1.01.22.3-1.2-1.51.30.90.0-0.7-0.71.01.01.11.21.01.41.21.1
Tail length5.923.242.5-6.5-6.06.55.1-4.61.20.73.95.75.44.94.85.14.33.1
Length with tail7.131.069.4-8.3-7.68.06.6-6.22.51.94.46.05.65.04.85.13.92.3
Length without tail3.19.927.3-5.2-4.84.74.1-4.12.52.32.22.62.32.12.02.01.10.2
Times rat made contact with spout4.45.010.8-2.8-2.42.83.3-2.90.50.22.52.12.32.22.32.11.61.4
Lifetime Intake0.70.83.7-1.7-1.91.40.7-0.70.90.90.20.80.60.40.20.40.3-0.1
Liver weight, left4.37.014.0-3.7-3.23.73.3-3.20.60.32.52.62.62.52.52.72.01.7
Liver weight, right3.05.28.9-2.8-2.23.03.0-2.80.40.12.42.52.42.32.42.11.91.6
Locomotor activity2.13.39.3-3.0-2.82.52.6-2.42.32.10.90.50.81.00.50.80.1-0.2
Locomotor testing distance1.52.78.2-2.5-2.31.72.0-1.92.92.80.3-0.4-0.10.1-0.20.0-0.8-1.0
Locomotor testing rearing0.30.62.4-1.2-1.50.90.8-0.41.11.0-0.00.10.40.50.30.60.30.2
Locomotion in novel chamber0.20.30.9-0.3-1.0-0.0-0.30.70.70.8-0.60.60.1-0.1-0.4-0.6-0.0-0.4
Locomotion in novel chamber post-restriction0.10.21.1-0.6-1.00.60.4-0.10.20.20.31.00.50.20.20.10.40.0
Fecal boli incidents, locomotor time 10.10.20.9-0.30.30.30.4-1.00.50.40.30.30.50.40.70.20.20.4
Change in fecal boli incidents, locomotor task2.32.34.81.30.6-1.6-2.22.1-0.20.1-1.1-2.2-1.8-1.5-1.5-1.3-1.4-1.6
Time >=10cm from walls, locomotor time 11.31.42.51.00.6-1.2-1.40.60.10.2-1.5-1.1-1.4-1.5-1.2-1.6-1.3-1.3
Bouts of movement, locomotor time 10.50.51.30.30.9-0.30.4-1.10.70.6-1.0-0.4-0.6-0.8-0.5-1.0-0.9-0.7
Total resting periods, locomotor time 10.30.31.30.71.2-0.60.0-0.50.1-0.0-0.8-0.3-0.4-0.7-0.2-0.8-0.5-0.4
Rest time, locomotor task time 10.70.92.81.71.5-1.4-1.01.1-1.1-1.0-0.7-0.3-0.5-0.70.1-1.00.1-0.0
Distance moved, locomotor task time 10.71.12.1-1.4-1.41.21.4-0.90.90.81.10.50.81.40.21.20.50.9
Vertical activity count, locomotor time 10.92.05.7-2.3-2.41.71.7-1.42.22.10.90.30.60.9-0.20.9-0.1-0.1
Time >=10cm from walls, locomotor time 20.40.61.50.91.2-0.4-0.00.3-1.1-1.20.40.80.60.50.50.10.80.9
Bouts of movement, locomotor time 20.30.52.50.1-0.2-0.4-0.70.70.60.6-1.6-0.7-0.5-0.8-1.0-0.2-0.5-0.6
Total resting periods, locomotor time 20.61.03.70.50.1-0.8-1.01.00.70.7-1.9-0.9-0.9-1.2-1.4-0.6-0.8-1.1
Rest time, locomotor task time 21.62.04.01.41.0-1.6-1.41.00.40.5-1.6-1.5-1.6-2.0-1.4-2.0-1.5-1.5
Distance moved, locomotor task time 21.82.24.8-1.0-0.41.41.9-1.3-0.5-0.71.91.61.72.21.11.51.51.9
Vertical activity count, locomotor time 23.24.411.3-2.7-1.52.83.4-3.31.00.72.31.81.92.21.41.61.11.4
Light reinforcement 10.10.31.5-0.7-0.40.61.2-0.60.30.31.10.60.30.40.2-0.2-0.1-0.3
Light reinforcement 20.40.61.70.20.9-0.3-0.1-0.50.40.4-0.4-0.7-1.0-0.7-0.8-1.2-1.2-1.3
Bone: marrow area2.04.311.2-0.8-0.1-0.10.3-1.73.43.3-1.3-2.2-2.2-2.1-1.6-2.0-2.9-2.8
Bone: maximum diameter1.83.312.3-2.5-2.21.61.9-2.23.53.4-0.3-0.1-0.4-0.4-0.3-0.6-1.2-1.2
Bone: maximum force0.61.12.2-0.6-0.50.10.1-0.61.41.4-1.5-0.9-1.1-1.3-1.3-1.0-1.4-1.3
Bone: maximum moment0.50.92.4-0.5-0.50.20.2-0.51.11.1-1.5-0.7-1.0-1.3-1.2-0.9-1.2-1.1
Mean time between licks in bursts0.30.71.8-0.2-0.7-0.3-0.30.51.31.3-1.3-0.9-0.8-0.7-0.9-0.5-0.7-0.8
Mean num. licks in bursts0.60.91.7-0.3-0.70.50.20.6-1.3-1.20.91.01.01.01.01.01.31.3
Cd content in liver0.50.51.10.10.9-0.20.3-0.90.90.8-0.6-0.6-0.6-0.8-1.0-0.7-1.1-0.9
Co content in liver0.30.31.9-0.3-0.9-0.20.20.11.41.40.2-0.10.10.20.40.10.00.1
Cu content in liver0.50.62.4-0.30.70.71.0-1.6-0.4-0.60.90.30.50.80.70.50.40.9
Fe content in liver0.81.02.8-0.5-0.20.2-0.50.10.90.9-1.6-1.0-1.1-1.2-1.7-0.8-1.2-1.3
K content in liver3.63.47.10.00.90.81.0-1.1-1.8-2.02.22.02.12.42.22.12.32.7
Mg content in liver0.70.71.70.70.9-0.30.0-0.1-1.0-1.10.90.70.70.91.00.81.01.3
Mn content in liver0.20.20.9-0.10.3-0.00.2-1.00.60.50.8-0.2-0.00.20.6-0.0-0.2-0.0
Na content in liver0.40.51.2-0.00.60.30.5-0.7-0.3-0.41.00.50.70.90.80.70.71.1
Rb content in liver0.50.51.90.91.0-0.4-0.90.4-1.2-1.4-0.50.40.30.00.10.30.60.9
Se content in liver0.30.41.20.41.1-0.5-0.4-0.10.60.60.5-0.8-0.7-0.3-0.3-0.6-1.0-0.7
Sr content in liver0.70.61.9-0.1-0.10.41.0-0.6-0.8-0.90.80.70.80.51.10.80.91.4
Zn content in liver3.03.36.0-1.5-1.51.81.7-1.1-0.6-0.72.51.72.12.32.22.22.02.3
Bone: minimum diameter2.44.413.5-3.4-3.12.32.3-2.43.73.5-0.3-0.0-0.2-0.3-0.5-0.3-1.1-1.1
Time in familiar zone, hab. session 10.30.30.80.60.7-0.6-0.50.1-0.1-0.00.3-0.5-0.6-0.50.4-0.9-0.5-0.5
Time in novel zone, hab. session 10.60.62.80.10.0-0.2-0.80.40.20.3-1.4-0.9-0.7-0.8-1.7-0.2-0.8-0.9
Total zone transitions, hab. session 10.91.23.1-1.4-1.51.11.8-1.01.31.21.30.70.71.01.00.70.40.7
Total locomotion distance, hab. session 11.01.54.0-1.3-1.41.11.9-0.80.50.52.00.91.01.51.70.40.80.9
Locomotion velocity, hab. session 11.82.66.2-1.6-1.81.42.5-0.90.70.62.51.31.52.02.20.91.21.4
Time in familiar zone, hab. session 20.10.10.30.20.1-0.1-0.30.1-0.3-0.2-0.4-0.2-0.3-0.3-0.5-0.3-0.2-0.3
Time in novel zone, hab. session 20.50.50.90.60.5-0.7-0.70.40.40.4-0.8-0.9-0.9-0.9-0.6-0.8-0.9-0.9
Total zone transitions, hab. session 20.40.52.0-0.4-0.9-0.10.20.21.41.4-0.3-0.5-0.6-0.3-0.2-0.8-0.7-0.8
Total locomotion distance, hab. session 20.40.51.8-0.5-0.80.10.9-0.31.31.40.5-0.3-0.30.30.5-0.8-0.5-0.5
Locomotion velocity, hab. session 20.40.62.3-0.5-0.90.00.9-0.21.51.50.6-0.4-0.30.40.6-0.7-0.4-0.4
Novel to familiar place preference ratio1.11.23.20.50.4-0.1-0.00.4-1.2-1.21.51.01.11.11.81.21.41.6
Novelty place preference1.21.33.40.80.7-0.4-0.30.6-1.5-1.51.40.81.01.01.81.11.41.6
Time in novel zone, NPP test0.91.02.50.70.6-0.3-0.30.4-1.3-1.31.20.60.80.81.60.91.21.3
Total zone transitions, NPP test0.40.62.3-0.8-1.20.30.5-0.31.51.5-0.6-0.8-0.7-0.3-0.4-0.3-0.7-0.5
Total locomotion distance, NPP test0.40.61.5-0.9-1.20.61.2-0.61.11.10.9-0.10.10.70.90.0-0.00.2
Locomotion velocity, NPP test0.30.51.0-0.6-1.00.31.0-0.20.90.91.0-0.10.10.81.00.10.10.3
Intraocular pressure0.30.41.20.60.2-0.7-0.50.7-0.00.1-0.8-0.9-0.7-0.8-1.1-0.3-0.6-0.6
Delta distance traveled before/after self-admin0.30.30.50.40.4-0.5-0.4-0.00.60.6-0.5-0.5-0.6-0.7-0.6-0.7-0.7-0.5
Delta ambulatory time before/after self-admin0.91.11.91.11.2-1.3-1.20.40.60.6-1.0-1.1-1.2-1.2-1.0-1.4-1.2-0.9
Parametrial fat weight1.53.56.80.10.6-0.8-0.1-0.72.62.6-1.5-2.1-2.0-2.1-2.3-2.2-2.5-2.6
Pavlov. Cond. lever latency0.60.71.6-0.6-0.50.1-0.4-0.41.21.3-0.9-0.9-0.8-1.1-0.9-0.4-1.1-1.1
Pavlov. Cond. magazine entry latency0.10.20.60.60.4-0.7-0.10.50.50.60.40.0-0.10.10.0-0.8-0.2-0.3
Pavlov. Cond. change in total contacts0.20.20.9-0.10.20.10.7-0.50.50.51.00.00.20.40.1-0.1-0.10.1
Pavlov. Cond. index score0.10.10.40.60.7-0.50.30.2-0.0-0.00.50.30.10.40.2-0.50.10.1
Pavlov. Cond. latency score0.20.20.60.60.7-0.40.40.2-0.4-0.40.80.50.30.60.5-0.30.40.4
Pavlov. Cond. lever contacts0.60.81.50.30.50.00.60.1-1.0-1.11.20.90.91.11.10.61.01.2
Pavlov. Cond. magazine entry number0.30.41.2-0.3-0.20.5-0.0-0.2-1.0-1.00.10.30.40.30.61.10.61.0
Pavlov. Cond. intertrial magazine entries1.41.74.3-0.3-0.3-0.2-0.90.31.41.5-1.7-1.3-1.4-1.4-2.1-1.2-1.6-1.6
Pavlov. Cond. lever-magazine prob. diff.0.10.10.50.50.6-0.50.30.00.30.30.30.0-0.10.1-0.0-0.7-0.2-0.1
Pavlov. Cond. response bias0.10.20.60.50.6-0.50.20.20.00.00.80.20.20.50.3-0.40.20.0
Pavlov. Cond. lever latency0.40.51.9-0.3-0.80.5-0.00.2-0.7-0.8-0.61.40.90.30.30.91.10.7
Pavlov. Cond. magazine entry latency0.20.20.7-0.5-0.80.4-0.00.5-0.2-0.10.80.10.40.80.60.40.50.5
Pavlov. Cond. change in total contacts0.71.14.4-1.4-1.50.70.6-0.52.12.10.6-1.0-0.30.20.10.1-0.7-0.4
Pavlov. Cond. index score0.20.31.1-0.7-0.70.40.3-0.10.90.91.0-0.50.00.60.30.2-0.2-0.0
Pavlov. Cond. latency score0.20.31.0-0.5-0.50.20.20.10.90.91.0-0.6-0.10.50.30.1-0.2-0.0
Pavlov. Cond. lever contacts0.50.72.1-0.00.6-0.30.3-0.61.11.20.5-1.5-1.0-0.4-0.5-0.9-1.3-0.9
Pavlov. Cond. magazine entry number0.50.62.21.11.1-0.6-0.60.3-1.4-1.5-1.10.4-0.0-0.6-0.20.10.40.4
Pavlov. Cond. intertrial magazine entries0.10.20.50.70.6-0.5-0.40.3-0.7-0.7-0.2-0.3-0.1-0.10.30.00.20.4
Pavlov. Cond. lever-magazine prob. diff.0.30.41.5-0.9-0.90.60.5-0.10.80.81.2-0.30.30.80.60.40.10.2
Pavlov. Cond. response bias0.30.51.4-0.5-0.20.20.5-0.51.11.20.6-1.1-0.6-0.1-0.2-0.6-0.9-0.6
Time in closed arm before self-admin0.30.41.7-0.7-1.30.50.20.5-0.1-0.10.30.70.60.60.50.70.70.3
Time in closed arm after self-admin0.20.20.7-0.8-0.80.50.3-0.40.40.50.0-0.4-0.3-0.20.3-0.3-0.3-0.4
Time in open arm before self-admin0.10.20.30.20.5-0.30.0-0.60.50.4-0.1-0.6-0.4-0.40.1-0.5-0.4-0.3
Time in open arm after self-admin1.41.56.51.92.6-1.7-1.20.3-0.2-0.2-0.9-1.1-1.1-1.1-1.1-1.0-1.1-0.5
Bone: periosteal estimation1.53.210.6-1.6-1.40.70.8-1.63.33.2-1.3-1.2-1.4-1.5-1.2-1.4-2.1-2.1
Bone: periosteal perimeter1.22.07.4-1.6-1.80.80.7-1.22.72.7-1.1-0.6-0.9-0.9-0.4-0.8-1.4-1.3
Bone: post-yield work0.10.20.5-0.5-0.20.40.3-0.40.10.1-0.2-0.3-0.4-0.6-0.6-0.6-0.7-0.7
Progressive ratio test 1 active lever presses3.34.09.9-3.1-3.13.02.1-2.10.80.61.62.31.91.61.61.61.40.8
Progressive ratio test 1 breakpoint3.44.29.9-3.2-3.13.02.2-2.10.70.61.62.42.01.71.71.71.40.9
Progressive ratio test 1 inactive lever presses0.10.10.3-0.3-0.30.30.3-0.60.10.10.00.60.30.1-0.0-0.10.2-0.1
Progressive ratio test 2 active lever presses1.41.63.5-1.5-1.61.71.0-0.6-0.5-0.50.91.91.61.41.11.21.51.0
Progressive ratio test 2 breakpoint1.51.73.7-1.5-1.71.71.1-0.5-0.4-0.50.91.91.61.51.11.21.51.0
Progressive ratio test 2 inactive lever presses0.30.41.5-0.2-0.40.50.20.3-1.2-1.20.40.80.60.60.30.40.90.5
Incentive Sensitization - Responses0.81.12.1-0.9-1.01.20.8-0.1-0.6-0.70.71.51.41.40.91.21.41.1
Incentive Sensitization - Breakpoint0.70.91.9-0.7-0.81.00.60.0-0.7-0.80.61.41.31.30.81.11.41.0
Sum of active levers in priming session hrs 5-61.11.02.2-0.5-0.10.81.3-1.0-0.5-0.61.51.01.11.21.11.30.91.2
Progressive ratio1.82.812.01.5-0.0-1.9-2.63.50.00.3-2.2-1.3-1.2-1.4-1.9-1.4-0.8-0.9
Food seeking constrained by brief footshock1.31.63.9-1.6-2.01.70.5-0.1-0.6-0.60.51.71.61.40.31.61.40.9
Seeking ratio, punishment vs. effort1.72.47.2-1.6-0.62.02.2-2.7-0.4-0.61.91.51.41.51.51.51.10.9
Retroperitoneal fat weight1.14.911.5-3.4-3.32.63.1-2.53.12.91.61.51.51.10.80.90.4-0.4
Reaction time number correct0.20.41.5-0.20.10.20.2-0.20.30.3-0.8-0.1-0.5-0.8-1.2-0.8-0.8-1.0
Reaction time mean minus median0.30.61.91.40.8-1.1-0.91.1-1.2-1.1-0.5-0.5-0.2-0.5-0.1-0.30.20.3
Reaction time mean minus median AUC0.30.82.61.40.8-1.0-0.81.0-1.6-1.6-0.10.00.2-0.20.40.10.60.6
Reaction time num false alarms0.40.62.21.21.5-0.7-0.60.0-1.3-1.3-0.40.2-0.1-0.3-0.2-0.30.10.3
Reaction time num false alarms AUC0.60.93.41.51.8-1.0-0.90.3-1.2-1.3-0.9-0.2-0.5-0.7-0.6-0.7-0.2-0.1
Reaction time trials correct on left0.20.41.5-0.20.10.20.2-0.20.30.3-0.8-0.1-0.5-0.8-1.2-0.8-0.8-1.0
Reaction time trials on left0.20.41.6-0.20.10.10.1-0.20.30.3-0.9-0.1-0.5-0.9-1.3-0.9-0.8-1.1
Reaction time mean0.30.41.0-0.1-0.6-0.2-0.10.21.01.0-0.8-0.9-0.6-0.7-0.8-0.5-0.7-0.7
Reaction time mean AUC0.10.20.6-0.3-0.80.10.00.00.70.7-0.6-0.4-0.3-0.5-0.5-0.2-0.4-0.5
Median of all reaction times0.50.72.5-0.8-1.10.30.3-0.31.61.6-0.6-0.7-0.5-0.5-0.8-0.4-0.8-0.9
Reaction time omissions1.72.54.82.21.7-2.2-2.01.9-0.5-0.4-1.6-1.7-1.6-1.7-1.0-1.8-1.1-1.1
Reaction time false alarm rate0.50.62.41.41.6-1.1-1.00.4-1.1-1.1-0.3-0.3-0.4-0.30.1-0.20.10.3
Reaction time premature initiation rate1.01.45.4-0.50.2-0.01.5-1.32.32.20.0-1.2-0.9-0.5-0.8-0.8-1.4-0.9
Reaction time premature initiations0.61.13.2-0.80.00.41.7-1.51.81.7-0.1-0.6-0.5-0.4-1.0-0.6-1.2-0.8
Std. dev. reaction times0.40.82.01.40.8-1.2-1.11.3-0.8-0.8-1.0-0.7-0.5-0.9-0.6-0.6-0.1-0.1
Reaction time trials completed0.20.41.6-0.20.10.10.1-0.20.30.3-0.9-0.1-0.5-0.9-1.3-0.9-0.8-1.1
Reaction time trials AUC0.20.51.7-0.30.00.20.2-0.40.50.5-0.9-0.1-0.5-0.9-1.3-0.9-0.9-1.2
Run reversals in cocaine runway, females0.20.21.3-0.7-1.10.60.5-0.20.30.3-0.10.20.1-0.00.40.30.2-0.1
Run reversals in cocaine runway, males0.30.30.9-0.00.50.40.4-0.7-0.9-0.90.90.30.40.30.50.20.30.3
Latency to leave start box in cocaine runway0.10.10.2-0.4-0.30.40.5-0.2-0.2-0.20.50.40.30.30.2-0.00.20.1
Latency to leave start box in cocaine runway, F0.40.40.90.80.8-0.8-0.50.30.10.20.4-1.0-0.8-0.5-0.2-0.9-0.8-0.6
Latency to leave start box in cocaine runway, M2.11.94.7-1.4-1.41.81.3-0.8-1.0-1.10.52.21.81.40.71.51.71.2
Std. dev. time between licks in bursts1.21.73.71.00.3-1.5-1.41.11.11.2-1.7-1.9-1.7-1.4-1.0-1.0-1.2-1.1
Total sessions with >9 infusions1.21.54.2-2.1-1.81.91.5-1.71.00.90.71.20.90.70.70.70.40.2
Short access day 1 total inactive lever presses0.10.20.4-0.1-0.20.1-0.1-0.30.20.2-0.4-0.5-0.5-0.6-0.6-0.6-0.6-0.5
Short access day 10 total inactive lever presses1.43.59.33.12.1-2.6-2.62.9-2.3-2.0-1.0-1.4-1.2-1.0-0.7-1.0-0.1-0.0
Short access day 1 total infusions0.20.30.8-0.3-0.9-0.0-0.50.40.70.7-0.5-0.5-0.6-0.7-0.4-0.5-0.6-0.7
Short access day 10 total infusions0.81.03.2-1.8-1.71.60.9-1.40.90.80.40.90.60.50.50.50.2-0.1
Short access total infusions0.40.52.5-1.2-1.60.90.4-0.51.01.00.00.50.20.00.20.0-0.0-0.3
Short access day 1 locomotion0.60.82.3-1.1-0.51.31.2-1.5-0.2-0.30.91.10.90.60.70.70.50.4
Short access day 10 total locomotion0.20.41.20.70.8-0.6-1.10.20.00.0-0.9-0.7-0.7-0.6-0.9-0.6-0.6-0.5
Short access total locomotion1.01.22.2-1.0-0.71.31.0-1.3-0.3-0.51.11.51.41.31.11.31.11.1
One hour access (0.3 mA shock)4.24.911.9-3.1-3.42.92.2-1.00.70.61.43.12.62.31.42.22.11.4
Compulsive drug intake0.30.41.30.0-0.60.0-0.11.0-0.3-0.30.11.20.90.70.10.61.10.5
One hour access (shock baseline)1.92.95.5-2.3-2.22.31.8-1.30.10.01.42.21.91.71.51.81.51.3
Social response proportion0.70.82.2-1.5-0.81.21.2-1.51.11.0-0.0-0.1-0.3-0.4-0.1-0.4-0.8-1.0
Social responses0.40.51.7-1.1-0.90.91.3-1.00.80.70.30.30.0-0.00.5-0.1-0.2-0.4
Social time0.91.33.5-1.4-0.51.81.9-1.7-1.1-1.20.91.00.90.80.50.90.60.3
Soleus weight0.61.73.0-0.8-0.40.30.6-1.21.71.7-1.6-1.1-1.4-1.4-1.6-1.3-1.7-1.6
Bone: stiffness1.93.29.8-2.1-1.01.41.9-3.03.13.0-0.3-0.6-0.7-0.7-0.7-1.0-1.7-1.7
Tibialis anterior weight0.82.78.2-0.10.2-0.3-0.4-0.41.41.4-2.9-1.2-1.7-1.8-2.8-1.8-2.0-2.2
Time to tail flick, vehicle, before self-admin4.44.68.2-2.2-1.82.32.8-2.10.60.32.42.22.42.42.22.92.02.1
Time to tail flick, vehicle, after self-admin0.70.93.51.51.9-1.2-1.10.0-0.9-0.9-0.3-0.6-0.8-0.9-0.1-0.8-0.7-0.6
Time to tail flick, test, before self-admin0.50.51.3-0.4-0.30.1-0.3-0.11.11.1-0.8-0.2-0.6-0.7-0.8-0.7-0.9-1.1
Time to tail flick, test, after self-admin0.10.10.3-0.5-0.50.30.2-0.20.60.6-0.0-0.3-0.2-0.3-0.2-0.0-0.4-0.5
Delta time to tail flick, vehicle, before/after SA4.03.87.52.42.3-2.3-2.71.5-1.0-0.8-1.7-1.9-2.2-2.2-1.5-2.3-1.7-1.8
Delta time to tail flick, test, before/after SA0.30.31.00.40.3-0.10.10.3-1.0-1.00.60.20.40.40.60.60.60.8
Tibia length4.612.636.0-5.8-6.05.04.4-3.42.92.62.52.72.72.92.52.91.81.2
Ambulatory time before self-admin0.10.21.0-0.7-0.60.71.0-0.3-0.1-0.10.40.40.30.3-0.10.20.10.1
Ambulatory time after self-admin1.11.22.30.1-0.2-0.7-0.30.71.41.5-1.2-0.9-1.1-1.3-1.5-1.5-1.4-1.3
Bone: tissue strength0.30.31.4-0.8-0.30.70.7-1.20.50.5-0.30.0-0.2-0.3-0.30.0-0.5-0.5
Total heroin consumption2.12.44.40.90.7-1.5-0.50.32.02.1-1.2-2.0-1.8-1.8-1.6-1.6-2.1-1.7
Bone: trabecular number0.10.20.70.30.7-0.10.3-0.0-0.6-0.7-0.20.80.2-0.1-0.60.00.2-0.1
Bone: trabecular spacing0.30.41.90.6-0.3-0.6-0.71.4-0.5-0.4-0.10.00.20.30.40.30.51.0
Bone: trabecular thickness0.40.51.9-0.50.30.81.0-1.4-0.5-0.61.00.90.70.50.70.30.40.0
Bone: trabecular tissue density0.20.31.20.00.4-0.20.3-0.41.01.01.10.10.30.30.2-0.3-0.1-0.3
Water consumed over 24 hours2.33.18.9-2.1-1.12.52.5-3.0-0.0-0.31.91.61.91.61.71.51.21.0
Number of responses in last shaping day0.30.30.9-0.1-0.90.2-0.60.7-0.9-0.80.10.40.30.10.50.10.5-0.1