Hub : Genes

Cep83

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose intron excision ratio chr7_29322957_29325469 0.03 0.02 1.5e-03 0.02 0.02 0.01 0.02 1.2e-03 1.6e-03 2.4e-02 2.6e-03
2 IL isoform ratio NM_001014266.2 0.17 0.1 8.1e-03 0.05 0.04 0.03 0.03 2.9e-02 4.3e-02 6.8e-02 5.2e-02
3 Adipose isoform ratio XM_008765318.3 0.03 0.02 4.0e-03 0.02 0.01 0 0.01 1.7e-03 1.1e-02 2.5e-01 9.2e-03
4 Liver gene expression Cep83 0.07 0.04 2.4e-04 0.02 0.04 0.05 0.04 1.4e-03 3.2e-05 3.0e-06 6.6e-05
5 Brain gene expression Cep83 0.15 0.05 2.2e-15 0.17 0.18 0.18 0.18 9.9e-16 1.2e-16 3.6e-16 7.8e-17
6 BLA gene expression Cep83 0.13 0.07 1.6e-04 0.06 0.07 0.08 0.08 4.4e-04 8.8e-05 4.8e-05 4.4e-05
7 PL gene expression Cep83 0.09 0.04 1.0e-09 0.1 0.09 0.1 0.1 8.5e-11 4.3e-10 2.8e-11 7.8e-11
8 NAcc gene expression Cep83 0.06 0.03 2.1e-06 0.05 0.06 0.05 0.06 3.5e-06 2.7e-07 1.0e-06 9.1e-08

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8
Bone: apparent density0.10.20.6-0.4-0.80.2-0.10.30.0-0.40.4
Area under the delay curve2.42.57.90.9-0.1-1.02.8-2.1-1.51.0-1.6
BMI with tail0.92.89.01.9-3.0-1.9-0.5-0.8-0.71.3-1.9
BMI without tail1.53.19.52.8-2.4-3.1-0.30.71.0-0.5-0.0
Body weight5.121.650.06.9-6.7-7.1-2.12.73.2-2.50.9
Weight adjusted by age0.20.20.40.0-0.30.1-0.60.60.5-0.50.5
Bone surface0.20.41.20.9-1.1-0.90.5-0.3-0.3-0.1-0.3
Bone volume0.20.31.70.5-1.3-0.60.2-0.1-0.2-0.2-0.0
Breakpoint value in progressive ratio session1.51.73.0-1.30.61.70.4-1.5-1.51.5-1.2
Number of licking bursts0.20.20.90.4-1.0-0.4-0.50.0-0.10.4-0.5
Context. condit. distance diff. score0.30.31.41.20.0-1.00.2-0.10.0-0.0-0.1
Locomotion velocity, session 10.40.51.6-1.10.51.3-0.2-0.2-0.30.5-0.4
Locomotion distance, session 10.10.20.40.1-0.50.1-0.5-0.3-0.30.5-0.7
Locomotion velocity, session 20.30.31.0-1.00.80.9-0.30.10.3-0.10.3
Locomotion distance, session 20.20.31.20.5-1.1-0.5-0.5-0.2-0.10.2-0.3
Locomotion velocity, session 30.10.10.3-0.4-0.40.6-0.2-0.1-0.10.2-0.3
Locomotion distance, session 30.30.30.90.7-0.9-0.5-0.1-0.4-0.40.6-0.6
Stereotopy head waving bouts, day 30.30.41.6-1.30.61.00.10.2-0.0-0.10.1
Stereotopy head waving duration, day 30.20.31.1-1.10.10.80.00.20.3-0.30.2
Locomotion velocity, session 70.20.20.7-0.40.50.2-0.80.2-0.10.4-0.3
Locomotion distance, session 70.10.10.2-0.2-0.00.2-0.2-0.3-0.40.4-0.2
Stereotopy head waving bouts, day 70.70.81.6-1.2-0.31.0-1.30.90.9-0.30.5
Stereotopy head waving duration, day 70.30.41.2-1.1-0.40.9-0.80.40.40.1-0.0
Locomotion velocity, session 80.20.20.60.20.2-0.3-0.20.60.6-0.80.6
Locomotion distance, session 81.11.65.62.4-1.5-2.2-0.50.00.2-0.2-0.2
Degree of sensitization distance0.10.10.4-0.60.40.40.3-0.3-0.2-0.00.2
Degree of sensitization stereotypy0.60.62.1-1.5-0.11.4-0.90.20.20.5-0.2
Conditioned locomotion0.10.10.5-0.50.70.50.1-0.1-0.10.2-0.2
Cocaine response after cond. corrected0.40.51.90.7-0.2-0.81.4-0.10.4-0.70.5
Cocaine response after cond. not corrected0.60.71.61.1-0.4-1.11.3-0.00.4-0.80.5
Cocaine response before conditioning0.10.10.30.6-0.0-0.2-0.40.20.1-0.10.1
Saline control response0.70.91.50.4-1.0-0.5-1.01.11.2-0.91.0
Bone: connectivity density0.20.30.7-0.7-0.20.5-0.10.50.3-0.70.8
Bone: cortical apparent density0.20.20.50.70.5-0.5-0.70.30.4-0.20.0
Bone: cortical area1.11.64.22.1-2.0-1.90.7-0.10.2-0.70.3
Bone: cortical porosity0.30.31.6-0.30.20.01.30.30.4-0.60.7
Bone: cortical porosity0.30.32.20.1-0.0-0.41.50.10.2-0.40.4
Bone: cortical thickness0.81.32.11.4-1.1-1.40.50.60.9-1.51.3
Bone: cortical thickness0.30.31.2-0.80.60.71.1-0.3-0.1-0.10.2
Bone: cortical tissue density0.20.20.50.60.6-0.5-0.70.30.5-0.20.1
Condit. Reinf. active minus inactive responses0.70.81.9-1.21.41.40.1-0.2-0.70.7-0.7
Condit. Reinf. active-inactive response ratio0.80.91.4-1.10.91.20.6-0.7-1.01.0-1.1
Condit. Reinf. active responses1.11.43.7-1.81.81.90.1-0.2-0.60.6-0.2
Condit. Reinf. inactive responses0.70.92.6-1.61.41.50.1-0.1-0.30.20.3
Incentive salience index mean0.20.20.5-0.50.60.7-0.50.50.0-0.10.0
Condit. Reinf. lever presses0.20.20.50.10.00.1-0.70.70.4-0.50.5
Condit. Reinf. active minus inactive responses0.60.72.1-1.40.21.5-1.0-0.1-0.50.6-0.2
Condit. Reinf. active-inactive response ratio0.30.40.9-0.7-0.70.7-0.90.30.3-0.20.5
Condit. Reinf. active responses0.60.81.7-1.20.51.3-0.8-0.3-0.80.9-0.6
Condit. Reinf. inactive responses1.31.64.1-0.92.01.01.0-1.0-1.31.3-1.3
Condit. Reinf. lever presses0.60.82.4-1.50.51.4-1.10.3-0.10.60.0
Condit. Reinf. lever reinforcers received0.60.91.5-1.10.31.2-1.0-0.5-1.01.2-0.9
Conditioned reinforcement - actives1.51.52.31.1-1.1-0.9-0.91.41.5-1.41.3
Conditioned reinforcement - inactives0.80.91.40.9-0.6-1.0-0.41.21.2-1.10.6
Conditioned locomotion1.82.13.01.6-1.3-1.3-1.21.61.6-1.71.4
Patch foraging indifference point 0 sec0.10.10.5-0.40.70.10.50.20.2-0.30.3
Patch foraging indifference point AUC0.70.81.30.0-1.0-0.3-0.91.11.0-1.11.0
Delay disc. indifference point, 0s delay0.40.40.6-0.80.20.50.6-0.8-0.60.8-0.8
Delay disc. indifference point, 16s delay3.43.56.61.3-0.9-1.32.6-2.5-1.91.4-2.2
Delay disc. indifference point, 2s delay0.40.41.11.0-0.9-1.10.3-0.4-0.1-0.2-0.3
Delay disc. indifference point, 24s delay2.12.03.82.0-0.9-1.91.9-1.5-0.90.2-1.0
Delay disc. indifference point, 4s delay0.50.63.50.30.5-0.51.9-0.6-0.0-0.1-0.3
Delay disc. indifference point, 8s delay3.03.111.80.20.3-0.13.4-2.2-1.71.4-1.8
Indifference point function ln k0.40.50.80.20.70.10.7-0.9-0.90.8-0.8
Indifference point function log k0.40.50.80.20.70.10.7-0.9-0.90.8-0.8
Patch foraging total patch changes 0 sec0.10.20.6-0.50.80.10.60.20.2-0.20.2
Patch foraging total patch changes 12 sec1.62.13.60.2-1.1-0.8-1.41.81.6-1.91.8
Patch foraging total patch changes 18 sec1.52.03.90.2-0.0-0.7-1.42.01.9-1.71.7
Patch foraging total patch changes 24 sec1.72.13.30.9-1.0-1.2-1.31.61.7-1.81.7
Patch foraging total patch changes 6 sec0.10.10.2-0.4-0.0-0.1-0.30.40.3-0.50.3
Patch foraging time to switch 0 sec0.10.10.4-0.20.6-0.0-0.00.20.4-0.10.2
Patch foraging water rate 0 sec0.91.44.52.1-1.7-2.0-0.30.00.1-0.1-0.3
Patch foraging water rate 12 sec1.52.36.91.4-2.6-1.3-1.41.41.5-1.01.0
Patch foraging water rate 18 sec0.50.72.1-0.1-1.40.3-0.6-0.6-0.81.0-1.1
Patch foraging water rate 24 sec1.52.16.92.6-2.2-2.2-0.60.20.2-0.0-0.3
Patch foraging water rate 6 sec2.02.98.22.6-2.9-2.3-1.50.71.0-0.2-0.1
Seeking ratio, delayed vs. immediate footshock0.10.10.6-0.10.20.00.8-0.10.1-0.30.2
Distance traveled before self-admin0.20.31.40.6-1.20.2-0.6-0.00.00.1-0.1
Distance traveled after self-admin0.70.81.80.8-1.3-0.5-0.2-0.9-1.10.7-1.2
Extensor digitorum longus weight0.10.61.50.7-1.2-0.81.2-0.5-0.2-0.0-0.2
Bone: elastic displacement2.12.34.6-2.02.02.21.9-1.0-1.10.4-0.1
Bone: elastic work1.11.55.0-1.21.51.32.2-0.9-0.8-0.10.2
Bone: endosteal estimation1.83.98.50.2-0.7-0.21.6-2.5-2.42.7-2.9
Bone: endosteal perimeter1.42.97.02.6-1.7-2.51.2-1.2-1.00.9-1.6
Epididymis fat weight1.33.08.52.2-2.9-2.0-2.50.60.40.1-0.5
Delta time in closed arm before/after self-admin0.30.31.40.6-1.2-0.7-0.4-0.0-0.1-0.1-0.3
Delta time in open arm before/after self-admin2.12.05.2-2.31.92.30.9-0.5-0.60.8-0.2
Diff in mean of infusions in LGA sessions0.60.71.6-1.21.01.30.4-0.6-0.60.6-0.2
Delay discount exponential model param2.12.27.7-1.10.21.2-2.81.91.3-0.71.3
Extinction: sum of active levers before priming0.30.30.6-0.4-0.30.50.2-0.7-0.60.7-0.6
Active lever presses in extinction session 60.70.71.3-0.1-0.90.00.2-1.1-1.11.0-1.1
Bone: final force0.91.42.80.9-1.7-0.91.5-1.1-1.00.9-1.3
Bone: final moment0.81.33.31.0-1.8-0.91.4-1.0-0.90.6-1.0
Food consumed during 24 hour testing period0.70.92.60.5-0.4-0.5-1.61.10.9-1.00.9
Glucose0.10.20.7-0.2-0.60.3-0.80.40.5-0.30.5
Heart weight1.01.43.0-0.1-1.00.31.4-1.7-1.41.2-1.4
Delay discount hyperbolic model param1.81.96.9-1.10.21.2-2.61.71.1-0.51.2
Intermittent access intake day 1-15 change2.12.13.70.9-1.1-1.0-1.31.91.8-1.61.5
Intermittent access intake escalation2.52.54.60.8-1.2-0.9-1.42.22.1-1.81.7
Intermittent access intake escalation 20.60.51.10.4-0.2-0.6-0.51.01.0-0.90.9
Intermitt. access day 1 inactive lever presses1.11.24.0-2.01.32.00.50.0-0.20.10.1
Intermitt. access day 15 inactive lever presses0.70.82.2-1.11.01.50.5-0.6-0.50.6-0.5
Intermitt. access escalation Index0.50.41.2-0.61.01.10.1-0.4-0.60.6-0.1
Intermittent access day 1 total infusions1.71.94.62.1-1.8-1.8-0.90.91.1-1.10.6
Intermittent access day 15 total infusions3.64.06.42.4-2.5-2.1-1.51.92.1-1.91.3
Intermittent access terminal intake (last 3 days)2.93.26.72.6-2.1-2.3-1.01.41.6-1.50.9
Intermittent access total infusions2.62.96.82.6-2.2-2.1-1.01.31.4-1.30.8
Intermittent access day 1 locomotion0.91.01.81.3-1.3-1.4-0.50.80.9-0.90.4
Intermittent access day 15 total locomotion4.54.97.31.9-1.5-2.0-1.82.72.7-2.72.1
Intermittent access total locomotion2.22.64.52.1-1.5-2.1-1.11.41.6-1.61.0
Intermittent access standard deviation3.94.25.22.3-2.0-2.3-1.62.12.1-2.11.8
Left kidney weight1.95.511.22.9-3.3-2.7-1.92.02.0-2.01.2
Right kidney weight1.02.77.82.3-2.8-2.2-1.10.91.0-1.00.4
Cocaine induced anxiety2.42.83.3-1.61.71.81.7-1.6-1.61.8-1.6
Post-drug Anxiety1.21.32.6-1.41.31.60.9-1.0-1.01.0-0.8
Baseline Anxiety1.31.42.20.7-0.8-0.8-1.51.21.2-1.41.5
Tail length5.416.430.75.3-3.2-5.5-1.73.94.3-4.03.2
Length with tail7.527.550.17.1-5.3-7.1-3.04.65.1-4.83.4
Length without tail3.57.614.43.8-3.6-3.5-1.82.22.4-2.31.5
Times rat made contact with spout4.85.68.62.4-2.9-2.4-2.52.32.1-2.31.7
Lifetime Intake1.82.16.52.6-1.9-2.0-0.70.70.9-0.80.3
Liver weight, left0.20.20.60.8-0.8-0.5-0.7-0.1-0.30.0-0.1
Liver weight, right0.10.20.50.2-0.3-0.3-0.70.70.4-0.30.3
Locomotor activity2.03.28.22.7-2.7-2.9-1.00.70.8-0.60.1
Locomotor testing distance1.01.74.72.2-1.9-2.1-0.3-0.3-0.10.3-0.9
Locomotor testing rearing0.40.62.01.4-0.3-1.40.50.20.5-0.40.1
Locomotion in novel chamber0.20.20.60.80.1-0.30.4-0.3-0.40.2-0.6
Locomotion in novel chamber post-restriction0.40.41.11.0-0.4-1.0-0.40.40.6-0.70.3
Fecal boli incidents, locomotor time 10.10.10.5-0.30.30.00.70.20.1-0.20.2
Change in fecal boli incidents, locomotor task1.11.02.4-0.20.50.1-0.0-1.4-1.41.5-1.3
Time >=10cm from walls, locomotor time 11.71.72.9-0.81.10.91.7-1.5-1.41.3-1.4
Bouts of movement, locomotor time 11.01.12.7-0.90.21.21.6-0.9-0.81.1-1.0
Total resting periods, locomotor time 10.91.02.5-1.10.51.31.6-0.7-0.60.9-0.8
Rest time, locomotor task time 11.11.23.4-1.81.01.80.9-0.4-0.50.6-0.7
Distance moved, locomotor task time 11.01.12.41.1-0.5-0.9-1.51.20.9-0.91.1
Vertical activity count, locomotor time 11.61.74.22.0-1.5-1.8-1.40.60.6-0.60.6
Time >=10cm from walls, locomotor time 20.70.82.1-1.40.91.40.10.60.5-0.50.7
Bouts of movement, locomotor time 20.50.63.10.40.4-0.21.8-0.6-0.30.4-0.5
Total resting periods, locomotor time 20.90.94.10.30.6-0.02.0-1.0-0.70.7-0.9
Rest time, locomotor task time 21.71.93.5-0.80.91.11.3-1.9-1.61.5-1.7
Distance moved, locomotor task time 21.61.84.00.1-0.60.2-1.82.01.5-1.31.6
Vertical activity count, locomotor time 23.43.75.81.2-2.4-1.4-2.22.22.0-1.82.0
Light reinforcement 10.50.94.00.4-1.70.0-2.00.40.20.2-0.1
Light reinforcement 20.60.81.6-1.0-0.20.9-0.1-0.8-1.11.3-1.0
Bone: marrow area1.73.88.20.2-0.7-0.21.6-2.4-2.42.7-2.9
Bone: maximum diameter1.12.15.52.4-2.2-2.20.3-0.7-0.50.4-0.9
Bone: maximum force0.91.53.20.7-1.2-0.71.8-1.5-1.31.0-1.4
Bone: maximum moment0.81.33.20.7-1.3-0.61.8-1.4-1.20.8-1.1
Mean time between licks in bursts0.20.30.90.9-0.1-1.00.8-0.3-0.2-0.1-0.3
Mean num. licks in bursts0.70.91.70.7-0.5-0.7-0.91.01.1-1.31.1
Cd content in liver0.50.51.00.3-0.8-0.60.5-0.8-0.60.9-1.0
Co content in liver2.02.43.51.8-0.7-1.9-1.21.71.6-1.71.4
Cu content in liver0.60.71.10.1-1.1-0.7-1.01.00.9-0.70.8
Fe content in liver0.60.71.00.9-0.9-0.60.7-0.9-0.80.9-1.0
K content in liver2.52.54.9-0.71.50.2-0.82.22.0-1.72.1
Mg content in liver0.60.61.7-0.61.30.2-0.31.01.0-0.50.6
Mn content in liver0.10.10.30.10.5-0.4-0.20.40.3-0.00.2
Na content in liver0.40.41.0-0.50.70.4-0.41.00.7-0.40.7
Rb content in liver0.81.03.2-1.11.81.01.20.50.7-0.50.8
Se content in liver0.50.61.5-0.60.30.4-1.2-0.4-0.51.2-0.9
Sr content in liver0.30.31.10.0-1.0-0.2-0.10.20.2-0.90.7
Zn content in liver0.40.51.00.30.1-0.5-0.70.81.0-0.90.8
Bone: minimum diameter2.03.810.63.3-3.1-3.00.2-0.4-0.20.1-0.7
Time in familiar zone, hab. session 10.40.40.8-0.70.10.8-0.3-0.4-0.50.9-0.6
Time in novel zone, hab. session 10.70.72.2-0.00.7-0.21.5-0.9-0.80.6-0.9
Total zone transitions, hab. session 11.01.43.71.4-1.9-1.0-1.60.70.7-0.50.5
Total locomotion distance, hab. session 11.62.26.71.4-2.3-0.8-2.61.20.9-0.70.5
Locomotion velocity, hab. session 12.53.69.71.8-2.7-1.2-3.11.71.4-1.20.9
Time in familiar zone, hab. session 20.10.10.1-0.20.00.20.3-0.1-0.30.2-0.3
Time in novel zone, hab. session 20.60.61.3-0.50.40.40.8-1.1-0.91.0-0.9
Total zone transitions, hab. session 20.30.40.90.8-0.8-0.4-0.2-0.6-0.50.7-0.9
Total locomotion distance, hab. session 20.40.51.20.8-1.1-0.4-0.9-0.1-0.30.5-0.8
Locomotion velocity, hab. session 20.30.51.00.9-1.0-0.4-0.9-0.0-0.30.5-0.7
Novel to familiar place preference ratio1.01.02.0-0.41.00.4-0.91.31.2-1.11.4
Novelty place preference1.01.01.9-0.71.20.6-0.71.21.1-1.01.4
Time in novel zone, NPP test0.70.71.3-0.61.00.5-0.61.00.9-0.81.2
Total zone transitions, NPP test0.40.51.41.2-1.0-0.90.2-0.6-0.40.3-0.5
Total locomotion distance, NPP test0.50.71.81.2-1.3-0.8-1.20.30.3-0.10.0
Locomotion velocity, NPP test0.40.51.61.0-1.0-0.5-1.30.40.3-0.10.1
Intraocular pressure0.10.20.5-0.20.00.5-0.1-0.5-0.70.4-0.3
Delta distance traveled before/after self-admin0.20.20.60.2-0.4-0.7-0.1-0.3-0.60.1-0.5
Delta ambulatory time before/after self-admin0.50.61.5-0.60.4-0.10.5-0.9-1.20.7-1.0
Parametrial fat weight1.52.94.9-1.31.01.01.3-2.1-1.92.2-2.2
Pavlov. Cond. lever latency0.70.91.50.7-0.2-0.71.1-1.2-0.91.1-1.1
Pavlov. Cond. magazine entry latency0.20.30.6-0.50.70.7-0.4-0.2-0.40.7-0.6
Pavlov. Cond. change in total contacts0.20.21.5-0.2-0.10.3-1.20.30.20.10.1
Pavlov. Cond. index score0.20.20.6-0.70.40.8-0.80.40.1-0.10.1
Pavlov. Cond. latency score0.30.41.2-0.70.10.8-1.10.60.3-0.30.4
Pavlov. Cond. lever contacts1.11.32.5-0.2-0.30.2-1.61.41.2-1.31.4
Pavlov. Cond. magazine entry number0.20.30.50.3-0.6-0.50.30.30.4-0.70.7
Pavlov. Cond. intertrial magazine entries1.31.63.30.3-0.0-0.41.4-1.6-1.41.6-1.8
Pavlov. Cond. lever-magazine prob. diff.0.10.10.4-0.50.30.6-0.60.2-0.10.1-0.1
Pavlov. Cond. response bias0.30.31.3-0.20.30.4-1.10.70.5-0.30.3
Pavlov. Cond. lever latency0.50.71.80.8-0.2-1.00.50.30.7-1.31.0
Pavlov. Cond. magazine entry latency0.40.51.10.9-0.4-0.8-1.00.80.6-0.50.4
Pavlov. Cond. change in total contacts0.50.72.31.5-0.7-1.3-0.5-0.1-0.20.5-0.6
Pavlov. Cond. index score0.20.31.10.7-0.3-0.5-1.10.40.10.3-0.3
Pavlov. Cond. latency score0.20.21.10.50.0-0.3-1.00.40.10.3-0.3
Pavlov. Cond. lever contacts0.60.82.4-0.6-0.50.6-0.6-0.6-0.91.5-1.3
Pavlov. Cond. magazine entry number0.50.62.1-1.10.70.91.5-0.3-0.0-0.30.5
Pavlov. Cond. intertrial magazine entries0.20.20.4-0.70.30.70.4-0.00.2-0.40.6
Pavlov. Cond. lever-magazine prob. diff.0.40.51.40.9-0.4-0.8-1.20.70.4-0.00.0
Pavlov. Cond. response bias0.40.51.20.2-0.8-0.1-0.7-0.2-0.51.1-1.0
Time in closed arm before self-admin0.50.51.71.2-0.3-1.3-0.40.40.5-0.70.4
Time in closed arm after self-admin0.50.52.50.6-1.6-0.7-0.5-0.3-0.30.1-0.5
Time in open arm before self-admin0.00.00.1-0.20.0-0.00.1-0.1-0.10.1-0.3
Time in open arm after self-admin1.21.44.0-1.72.01.60.9-0.2-0.30.50.0
Bone: periosteal estimation1.22.53.41.6-1.6-1.41.5-1.7-1.61.4-1.8
Bone: periosteal perimeter1.11.84.02.0-1.5-1.91.2-1.0-0.90.4-0.9
Bone: post-yield work0.30.52.60.3-1.6-0.2-0.3-0.4-0.10.6-0.6
Progressive ratio test 1 active lever presses5.96.212.93.4-3.6-3.1-1.61.82.1-1.91.2
Progressive ratio test 1 breakpoint5.55.712.43.3-3.5-3.1-1.61.71.9-1.71.1
Progressive ratio test 1 inactive lever presses0.30.30.80.5-0.9-0.2-0.60.60.5-0.70.4
Progressive ratio test 2 active lever presses3.33.55.32.3-2.1-2.0-1.41.92.0-1.91.3
Progressive ratio test 2 breakpoint3.84.36.62.6-2.3-2.3-1.62.12.2-2.01.4
Progressive ratio test 2 inactive lever presses0.80.91.60.6-1.3-0.4-1.01.01.0-1.10.7
Incentive Sensitization - Responses3.23.35.21.7-1.1-1.6-1.32.32.2-2.11.7
Incentive Sensitization - Breakpoint2.93.05.01.5-0.9-1.5-1.22.22.2-2.11.7
Sum of active levers in priming session hrs 5-60.20.20.70.1-0.80.0-0.80.40.3-0.40.5
Progressive ratio1.31.54.1-0.02.00.31.5-1.3-1.30.8-1.1
Food seeking constrained by brief footshock1.61.93.21.8-0.8-1.8-0.81.41.6-1.51.1
Seeking ratio, punishment vs. effort1.31.63.00.7-1.7-0.9-1.31.51.5-1.11.2
Retroperitoneal fat weight0.93.18.93.0-2.2-2.6-1.90.50.5-0.2-0.4
Reaction time number correct0.30.51.4-0.1-1.20.10.0-0.8-0.50.8-0.9
Reaction time mean minus median0.30.41.0-0.91.00.70.8-0.4-0.10.00.1
Reaction time mean minus median AUC0.30.31.1-0.81.00.60.40.00.4-0.30.4
Reaction time num false alarms0.60.82.2-1.51.31.40.90.1-0.1-0.10.3
Reaction time num false alarms AUC1.01.43.5-1.91.41.81.3-0.4-0.50.4-0.1
Reaction time trials correct on left0.30.51.4-0.1-1.20.10.0-0.8-0.50.8-0.9
Reaction time trials on left0.30.51.2-0.1-1.10.20.1-0.8-0.60.8-0.9
Reaction time mean0.20.30.60.60.0-0.60.6-0.7-0.50.5-0.8
Reaction time mean AUC0.20.20.70.7-0.1-0.90.5-0.4-0.20.1-0.4
Median of all reaction times0.40.51.21.0-0.5-1.10.3-0.6-0.40.5-1.0
Reaction time omissions2.12.93.7-1.91.41.61.6-1.9-1.91.7-1.6
Reaction time false alarm rate0.81.23.4-1.61.81.41.1-0.0-0.30.10.2
Reaction time premature initiation rate0.40.61.3-0.2-1.10.4-0.5-0.7-0.80.9-0.9
Reaction time premature initiations0.50.73.4-0.1-1.80.2-0.8-0.5-0.40.7-0.8
Std. dev. reaction times0.40.51.3-0.81.00.61.2-0.7-0.30.3-0.3
Reaction time trials completed0.30.51.2-0.1-1.10.20.1-0.8-0.60.8-0.9
Reaction time trials AUC0.40.51.5-0.1-1.20.10.1-0.9-0.60.9-1.0
Run reversals in cocaine runway, females0.50.51.51.2-0.9-1.20.4-0.2-0.1-0.2-0.3
Run reversals in cocaine runway, males0.20.20.4-0.6-0.10.6-0.60.20.30.10.2
Latency to leave start box in cocaine runway0.20.20.90.4-0.5-0.2-0.90.00.2-0.0-0.1
Latency to leave start box in cocaine runway, F0.40.41.2-0.60.30.5-1.1-0.4-0.60.6-0.5
Latency to leave start box in cocaine runway, M2.32.33.41.7-1.4-1.4-0.91.51.8-1.61.5
Std. dev. time between licks in bursts1.72.04.5-0.41.70.42.1-1.5-1.51.3-1.4
Total sessions with >9 infusions1.11.34.12.0-1.8-1.5-0.50.10.3-0.3-0.1
Short access day 1 total inactive lever presses0.00.00.20.2-0.40.0-0.4-0.1-0.0-0.20.0
Short access day 10 total inactive lever presses1.92.15.5-2.32.32.30.3-0.4-0.60.30.1
Short access day 1 total infusions1.11.24.32.1-1.3-1.7-0.50.00.3-0.40.1
Short access day 10 total infusions2.02.26.42.5-2.1-1.8-0.70.91.0-0.90.4
Short access total infusions1.82.06.52.6-2.1-1.9-0.60.50.7-0.60.1
Short access day 1 locomotion1.71.93.91.6-2.0-1.5-1.21.11.2-1.10.9
Short access day 10 total locomotion0.10.10.30.50.2-0.50.20.10.2-0.30.1
Short access total locomotion1.92.02.61.6-1.6-1.5-1.11.41.5-1.51.1
One hour access (0.3 mA shock)3.13.68.32.9-1.1-2.6-1.01.71.8-2.01.2
Compulsive drug intake1.11.25.1-1.02.31.20.8-0.6-0.60.4-0.4
One hour access (shock baseline)4.04.77.92.8-2.3-2.5-1.62.02.1-2.11.6
Social response proportion1.01.15.60.8-2.4-0.7-0.0-0.7-0.50.7-1.0
Social responses0.50.74.00.9-2.0-0.8-0.3-0.10.0-0.0-0.3
Social time1.41.810.00.5-3.2-0.9-1.30.70.9-0.70.5
Soleus weight0.31.02.00.5-1.4-0.30.8-1.2-1.20.8-1.1
Bone: stiffness1.32.05.01.1-2.2-1.50.8-1.2-1.01.4-1.7
Tibialis anterior weight0.72.56.5-0.1-0.10.02.6-2.0-1.81.6-1.9
Time to tail flick, vehicle, before self-admin5.55.67.02.3-1.7-2.2-2.22.62.7-2.62.6
Time to tail flick, vehicle, after self-admin1.81.94.3-1.91.32.11.1-1.1-1.11.3-0.9
Time to tail flick, test, before self-admin0.20.20.40.4-0.3-0.60.3-0.5-0.40.3-0.6
Time to tail flick, test, after self-admin0.10.10.10.2-0.3-0.4-0.20.10.1-0.20.3
Delta time to tail flick, vehicle, before/after SA5.75.67.2-2.72.22.62.1-2.4-2.42.3-2.2
Delta time to tail flick, test, before/after SA0.30.30.7-0.30.30.4-0.30.60.6-0.50.9
Tibia length5.415.435.96.0-4.8-5.7-2.52.52.8-2.81.8
Ambulatory time before self-admin0.50.52.40.4-1.60.5-0.90.40.4-0.10.3
Ambulatory time after self-admin0.60.71.80.8-1.4-0.4-0.2-0.8-0.90.6-1.0
Bone: tissue strength0.20.21.30.4-1.2-0.6-0.0-0.2-0.10.0-0.1
Total heroin consumption0.70.81.9-0.50.50.50.3-1.2-1.41.1-1.1
Bone: trabecular number0.10.10.3-0.6-0.20.40.10.2-0.0-0.30.2
Bone: trabecular spacing0.20.20.80.30.90.10.10.10.3-0.50.7
Bone: trabecular thickness0.40.41.6-0.3-1.30.1-0.80.50.5-0.40.5
Bone: trabecular tissue density0.20.30.6-0.30.70.5-0.50.1-0.10.8-0.7
Water consumed over 24 hours0.81.01.30.6-1.2-1.0-1.01.11.1-1.00.9
Number of responses in last shaping day1.11.12.81.7-1.2-1.4-0.70.70.9-0.80.4