Hub : Genes

Mlh1

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 IL mRNA stability Mlh1 0.18 0.13 3.1e-03 0.02 0.02 0.06 0.01 1.3e-01 9.4e-02 1.5e-02 2.3e-01
2 BLA intron excision ratio chr8_111231159_111233433 0.47 0.2 7.9e-04 0.04 0.05 0.05 0.04 4.1e-03 1.1e-03 9.7e-04 4.1e-03
3 Eye gene expression Mlh1 0.48 0.23 9.8e-05 0.09 0.15 0.09 0.12 1.6e-02 2.5e-03 1.7e-02 7.2e-03
4 Liver gene expression Mlh1 0.55 0.1 0.0e+00 0.6 0.6 0.61 0.61 5.5e-83 3.2e-84 5.9e-85 2.6e-85
5 PL isoform ratio XR_005487930.1 0.04 0.02 2.9e-05 0.04 0.04 0.04 0.04 1.1e-05 4.0e-05 4.4e-05 1.4e-05
6 Brain gene expression Mlh1 0.49 0.11 0.0e+00 0.67 0.68 0.68 0.68 9.7e-83 2.0e-85 5.2e-86 1.8e-85
7 RMTg gene expression Mlh1 0.37 0.14 2.4e-09 0.29 0.25 0.26 0.27 1.6e-08 2.3e-07 1.5e-07 5.3e-08
8 PL gene expression Mlh1 0.84 0 0.0e+00 0.56 0.57 0.59 0.58 6.0e-74 4.6e-76 9.3e-81 3.1e-79
9 Adipose gene expression Mlh1 0.74 0.08 0.0e+00 0.64 0.66 0.67 0.66 1.6e-91 8.8e-99 2.0e-100 1.2e-98
10 OFC gene expression Mlh1 0.69 0.15 1.2e-15 0.24 0.3 0.28 0.3 2.3e-06 8.1e-08 2.4e-07 7.4e-08
11 RMTg intron excision ratio chr8_111218688_111219036 0.13 0.09 3.9e-03 0.04 0.03 -0.01 0.01 3.7e-02 5.6e-02 7.5e-01 1.4e-01
12 RMTg intron excision ratio chr8_111218949_111219036 0.14 0.09 3.4e-03 0.04 0.03 -0.01 0.02 3.2e-02 4.9e-02 5.6e-01 9.6e-02
13 LHb gene expression Mlh1 0.68 0.12 0.0e+00 0.27 0.33 0.28 0.31 4.1e-07 1.5e-08 2.6e-07 4.5e-08
14 Liver mRNA stability Mlh1 0.02 0.02 1.7e-03 0.02 0.01 0 0.02 1.3e-03 1.7e-02 2.6e-01 4.7e-03
15 Brain intron excision ratio chr8_111216930_111218600 0.02 0.02 9.4e-03 0.02 0.02 0 0.01 7.7e-03 4.6e-03 1.5e-01 1.6e-02
16 BLA gene expression Mlh1 0.47 0.13 0.0e+00 0.54 0.51 0.52 0.53 1.6e-33 3.5e-31 7.7e-32 1.0e-32
17 IL gene expression Mlh1 0.55 0.14 5.4e-14 0.38 0.43 0.42 0.41 3.6e-10 1.5e-11 2.5e-11 4.5e-11
18 NAcc gene expression Mlh1 0.6 0.1 0.0e+00 0.55 0.54 0.58 0.58 5.0e-77 7.2e-75 7.0e-82 3.2e-82
19 Adipose isoform ratio XR_005487930.1 0.07 0.04 2.4e-08 0.06 0.05 0.05 0.05 1.2e-07 5.2e-06 1.7e-06 2.5e-06
20 pVTA gene expression Mlh1 0.47 0.13 0.0e+00 0.42 0.4 0.4 0.42 1.5e-19 2.0e-18 8.0e-19 1.3e-19
21 Adipose intron excision ratio chr8_111218688_111219036 0.03 0.02 6.6e-04 0.02 0.03 0 0.02 2.6e-03 5.8e-04 7.6e-02 1.6e-03
22 BLA isoform ratio XR_005487930.1 0.06 0.04 2.1e-03 0.06 0.04 0.06 0.05 5.0e-04 2.5e-03 5.5e-04 1.6e-03
23 Brain isoform ratio XR_005487930.1 0.04 0.03 1.1e-03 0.01 0.01 0 0 8.6e-02 4.4e-02 2.5e-01 1.0e-01
24 NAcc isoform ratio XR_005487930.1 0.04 0.04 2.6e-03 0.03 0 0.01 0.02 4.4e-04 7.8e-02 1.4e-02 2.1e-03
25 Adipose mRNA stability Mlh1 0.09 0.06 1.4e-04 0.01 0.01 0.02 0.01 1.0e-02 8.7e-03 4.4e-03 5.9e-02
26 NAcc mRNA stability Mlh1 0.14 0.1 4.1e-03 0 0.01 0.01 0 1.4e-01 4.1e-02 3.4e-02 3.2e-01

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26
Bone: apparent density0.00.10.5-0.1-0.10.40.2-0.2-0.2-0.1-0.4-0.00.10.2-0.20.0-0.20.1-0.1-0.20.3-0.30.20.2-0.20.70.30.4-0.3
Area under the delay curve2.22.33.41.7-1.4-1.5-1.51.21.61.71.41.7-1.6-1.51.5-1.71.5-1.61.5-1.8-1.51.3-1.61.81.5-0.81.41.61.1
BMI with tail0.72.16.6-1.62.31.11.6-1.8-1.6-1.0-1.3-1.41.01.7-1.71.4-1.11.6-0.91.81.0-1.11.1-1.6-1.00.7-2.6-1.4-0.5
BMI without tail1.83.77.0-2.32.41.82.0-2.2-2.2-1.9-1.7-2.01.72.3-2.31.9-1.82.1-1.62.01.6-1.51.8-1.9-1.81.7-2.6-1.1-0.2
Body weight6.928.935.8-6.05.95.45.7-5.8-5.7-5.3-5.6-5.65.25.7-5.75.7-5.35.7-5.15.95.3-5.35.2-5.6-5.24.1-5.4-4.3-3.4
Weight adjusted by age0.50.52.1-0.60.70.50.4-0.5-0.6-0.5-0.6-0.70.50.7-0.70.8-0.50.7-0.41.00.8-0.70.6-0.9-0.6-0.1-0.7-1.5-1.3
Bone surface0.10.10.40.4-0.6-0.1-0.20.20.20.3-0.00.4-0.3-0.10.1-0.30.3-0.30.3-0.2-0.20.3-0.30.40.3-0.10.70.5-0.3
Bone volume0.00.10.40.2-0.50.1-0.00.00.00.2-0.20.2-0.10.0-0.0-0.10.1-0.10.2-0.10.10.1-0.10.30.10.20.50.3-0.6
Breakpoint value in progressive ratio session0.10.10.5-0.7-0.20.30.2-0.3-0.2-0.4-0.1-0.20.30.5-0.50.1-0.00.1-0.3-0.00.50.40.30.1-0.30.40.2-0.6-0.6
Number of licking bursts0.10.10.90.3-0.3-0.5-0.40.40.30.30.50.2-0.3-0.40.4-0.20.4-0.30.30.0-0.30.4-0.3-0.00.3-0.9-0.1-0.6-0.0
Context. condit. distance diff. score0.00.10.50.1-0.50.20.0-0.00.00.0-0.30.0-0.00.1-0.10.1-0.10.00.00.30.20.00.0-0.1-0.0-0.30.7-0.2-0.7
Locomotion velocity, session 10.10.10.40.5-0.6-0.1-0.20.20.20.20.30.3-0.2-0.10.1-0.30.3-0.20.2-0.3-0.30.5-0.20.40.20.10.30.70.6
Locomotion distance, session 10.81.02.4-0.90.41.31.2-1.3-1.1-1.0-1.1-0.91.01.3-1.30.9-1.01.0-0.90.80.9-0.71.0-0.6-1.01.5-0.40.1-0.3
Locomotion velocity, session 20.20.30.90.6-1.0-0.4-0.40.40.50.50.40.6-0.5-0.40.4-0.50.7-0.50.5-0.4-0.40.7-0.60.60.6-0.50.80.1-0.3
Locomotion distance, session 20.10.11.60.4-0.10.20.2-0.2-0.10.0-0.10.2-0.10.2-0.2-0.20.0-0.00.1-0.4-0.10.2-0.10.50.10.80.11.30.5
Locomotion velocity, session 30.10.10.7-0.1-0.10.50.4-0.5-0.4-0.0-0.5-0.00.10.5-0.50.2-0.20.3-0.10.00.3-0.10.20.2-0.20.8-0.10.1-0.4
Locomotion distance, session 30.91.02.21.4-1.5-0.6-0.80.70.81.20.41.3-1.1-0.80.8-1.01.0-1.01.2-1.1-0.71.0-1.11.41.1-0.31.40.9-0.6
Stereotopy head waving bouts, day 30.20.20.9-0.30.6-0.00.2-0.2-0.2-0.3-0.0-0.50.30.2-0.20.5-0.30.4-0.20.90.1-0.20.3-1.0-0.3-0.8-0.8-1.00.1
Stereotopy head waving duration, day 30.40.51.2-0.71.10.30.5-0.5-0.6-0.7-0.3-0.80.70.5-0.50.7-0.70.7-0.70.90.4-0.70.7-1.1-0.7-0.1-1.1-0.70.4
Locomotion velocity, session 70.30.31.7-0.20.30.80.6-0.6-0.5-0.6-0.7-0.40.50.6-0.60.4-0.60.5-0.60.00.6-0.70.6-0.1-0.61.3-0.10.7-0.2
Locomotion distance, session 70.70.94.91.4-0.8-0.6-0.80.70.80.80.61.0-0.8-0.70.7-0.90.7-0.90.8-1.2-0.90.7-0.81.10.80.01.12.20.8
Stereotopy head waving bouts, day 70.20.20.60.4-0.4-0.3-0.30.40.30.30.40.5-0.4-0.40.4-0.50.4-0.50.4-0.8-0.30.4-0.40.70.40.20.30.60.3
Stereotopy head waving duration, day 70.10.20.6-0.50.20.50.5-0.4-0.5-0.4-0.4-0.30.40.4-0.40.3-0.40.4-0.40.10.5-0.30.4-0.1-0.40.8-0.3-0.3-0.3
Locomotion velocity, session 80.40.42.2-0.3-0.51.00.7-0.8-0.6-0.4-1.0-0.30.40.8-0.80.6-0.40.5-0.40.50.8-0.30.5-0.1-0.50.70.5-0.5-1.5
Locomotion distance, session 80.30.41.8-0.2-0.11.00.8-0.9-0.7-0.5-0.9-0.30.40.9-0.90.4-0.50.5-0.40.20.5-0.40.50.1-0.51.40.20.8-0.3
Degree of sensitization distance1.21.22.2-1.21.51.01.0-0.9-1.0-1.3-0.8-1.31.21.0-1.01.1-1.11.1-1.30.90.8-1.21.2-1.2-1.21.0-1.20.30.7
Degree of sensitization stereotypy0.10.10.60.1-0.4-0.0-0.10.20.10.10.10.4-0.1-0.20.2-0.40.2-0.30.1-0.8-0.10.2-0.20.70.20.80.30.80.1
Conditioned locomotion3.03.54.52.0-1.8-1.9-2.02.02.01.91.92.0-2.0-2.02.0-2.01.8-2.01.9-2.1-1.81.8-1.92.01.9-1.41.71.11.0
Cocaine response after cond. corrected0.30.41.1-0.41.10.20.5-0.4-0.5-0.4-0.2-0.70.60.4-0.40.7-0.60.6-0.50.90.2-0.60.5-1.0-0.5-0.2-1.0-0.60.5
Cocaine response after cond. not corrected1.92.13.8-1.51.91.11.4-1.3-1.5-1.3-1.1-1.61.51.4-1.41.6-1.51.6-1.41.81.1-1.41.4-1.9-1.40.6-1.9-1.6-0.2
Cocaine response before conditioning1.21.52.7-1.60.81.31.3-1.3-1.4-1.1-1.3-1.11.11.4-1.41.2-1.11.2-1.11.11.3-1.01.2-1.0-1.11.2-1.1-1.3-1.2
Saline control response1.31.63.6-1.11.61.51.3-1.3-1.2-1.4-1.3-1.21.31.3-1.31.2-1.61.2-1.40.81.3-1.51.4-1.0-1.41.9-0.90.60.1
Bone: connectivity density0.30.51.50.6-0.7-0.5-0.70.70.60.60.60.7-0.6-0.60.6-0.80.5-0.70.6-1.1-0.60.5-0.50.90.50.20.91.20.7
Bone: cortical apparent density0.50.62.60.5-1.5-0.4-0.70.80.80.60.30.9-0.7-0.70.7-0.70.7-0.80.6-0.8-0.40.6-0.61.00.6-0.41.60.7-0.4
Bone: cortical area0.20.21.30.2-0.6-0.3-0.40.40.40.30.10.3-0.3-0.40.4-0.10.4-0.30.30.2-0.10.3-0.30.00.3-1.10.5-1.0-1.1
Bone: cortical porosity0.20.31.50.20.0-0.2-0.30.40.20.10.50.3-0.2-0.40.4-0.50.0-0.30.1-1.0-0.30.1-0.10.70.10.90.11.21.2
Bone: cortical porosity0.40.42.40.30.1-0.5-0.50.50.40.30.70.5-0.4-0.60.6-0.70.2-0.50.3-1.2-0.60.3-0.30.70.30.6-0.01.31.5
Bone: cortical thickness0.30.54.0-0.6-0.20.60.4-0.4-0.4-0.4-0.9-0.40.40.4-0.40.7-0.30.4-0.41.10.8-0.50.4-0.7-0.4-0.70.2-1.5-2.0
Bone: cortical thickness0.00.00.2-0.00.00.20.1-0.1-0.0-0.1-0.2-0.00.10.1-0.10.1-0.10.1-0.10.10.1-0.20.1-0.0-0.10.1-0.10.4-0.1
Bone: cortical tissue density0.50.62.80.5-1.5-0.4-0.70.80.80.70.30.9-0.7-0.70.7-0.70.7-0.80.7-0.9-0.40.6-0.71.00.7-0.31.70.6-0.4
Condit. Reinf. active minus inactive responses0.10.10.2-0.10.20.30.2-0.1-0.2-0.3-0.2-0.40.40.2-0.20.3-0.30.3-0.40.30.3-0.30.4-0.4-0.40.1-0.10.10.1
Condit. Reinf. active-inactive response ratio0.20.20.5-0.40.40.40.4-0.3-0.3-0.6-0.3-0.60.60.4-0.40.6-0.50.5-0.60.60.4-0.50.6-0.7-0.60.1-0.2-0.2-0.0
Condit. Reinf. active responses0.10.10.20.5-0.2-0.3-0.30.30.30.30.30.2-0.3-0.20.2-0.20.2-0.20.2-0.2-0.20.2-0.10.10.1-0.3-0.00.40.3
Condit. Reinf. inactive responses0.70.91.31.1-0.8-1.0-1.00.90.91.10.91.1-1.1-0.90.9-1.01.0-0.91.1-1.0-0.91.0-1.01.01.0-0.60.30.70.5
Incentive salience index mean0.10.10.30.4-0.2-0.3-0.30.30.30.30.30.2-0.2-0.20.2-0.20.3-0.20.2-0.2-0.30.2-0.20.20.2-0.20.20.60.4
Condit. Reinf. lever presses1.31.72.21.5-1.2-1.4-1.31.31.31.41.41.4-1.4-1.21.2-1.41.4-1.31.4-1.4-1.41.3-1.41.41.3-0.90.81.21.0
Condit. Reinf. active minus inactive responses2.22.74.0-1.51.02.01.9-1.7-1.6-1.6-2.0-1.71.81.8-1.81.8-1.81.7-1.71.91.8-1.61.6-1.6-1.61.2-0.5-1.1-1.7
Condit. Reinf. active-inactive response ratio1.71.82.6-1.31.61.21.5-1.4-1.4-1.3-1.2-1.51.41.4-1.41.4-1.41.4-1.41.61.1-1.21.2-1.6-1.20.8-1.5-1.0-0.4
Condit. Reinf. active responses1.72.33.5-1.20.91.91.7-1.6-1.4-1.6-1.9-1.61.71.6-1.61.7-1.71.5-1.71.81.6-1.51.6-1.6-1.61.0-0.2-0.5-1.4
Condit. Reinf. inactive responses0.10.22.00.5-1.00.2-0.20.20.30.0-0.20.2-0.0-0.10.1-0.00.1-0.20.00.00.00.10.00.1-0.0-0.31.40.7-0.5
Condit. Reinf. lever presses2.43.25.0-1.81.52.22.0-2.0-1.8-1.8-2.2-1.81.92.0-2.02.0-2.01.8-1.82.01.8-1.81.8-1.7-1.81.5-0.7-0.7-1.4
Condit. Reinf. lever reinforcers received2.02.84.0-1.51.22.01.9-1.8-1.6-1.8-2.0-1.71.91.8-1.81.9-1.91.7-1.82.01.7-1.71.7-1.7-1.71.2-0.4-0.6-1.3
Conditioned reinforcement - actives0.40.44.60.1-0.1-0.2-0.70.10.30.30.70.4-0.7-0.10.1-0.30.0-0.30.7-0.4-0.51.00.00.3-0.1-0.00.31.22.1
Conditioned reinforcement - inactives0.70.72.60.3-0.7-1.1-1.00.70.81.01.10.7-0.9-0.80.8-0.70.7-0.81.0-0.3-1.01.2-0.80.30.8-1.60.4-0.31.0
Conditioned locomotion0.70.97.50.50.3-0.5-0.80.40.60.51.00.6-0.8-0.40.4-0.70.4-0.60.8-0.9-0.91.0-0.30.70.30.30.22.32.7
Patch foraging indifference point 0 sec1.11.82.9-1.51.51.51.4-1.4-1.3-1.3-1.5-1.31.41.1-1.11.3-1.61.3-1.50.91.5-1.51.3-1.0-1.31.7-1.1-0.8-1.0
Patch foraging indifference point AUC0.10.21.0-0.1-0.10.60.3-0.4-0.1-0.1-0.50.10.10.1-0.10.0-0.40.0-0.2-0.30.4-0.20.20.5-0.21.00.80.6-0.4
Delay disc. indifference point, 0s delay0.10.10.80.10.9-0.2-0.1-0.30.00.30.00.1-0.1-0.10.1-0.10.1-0.00.1-0.20.0-0.2-0.10.10.00.1-0.4-0.10.2
Delay disc. indifference point, 16s delay1.21.22.11.3-1.4-1.0-1.01.01.11.10.91.2-1.0-1.11.1-1.21.0-1.11.0-1.3-1.10.9-1.11.21.1-0.51.11.50.9
Delay disc. indifference point, 2s delay0.30.30.50.6-0.3-0.6-0.60.20.60.70.60.7-0.6-0.50.5-0.60.5-0.60.6-0.7-0.50.6-0.60.70.5-0.30.60.40.5
Delay disc. indifference point, 24s delay1.11.12.61.1-1.6-0.9-1.00.81.01.11.01.1-1.0-0.90.9-1.10.8-1.00.9-1.1-1.11.0-0.91.10.9-0.61.11.41.2
Delay disc. indifference point, 4s delay2.22.33.11.8-1.3-1.5-1.51.11.61.61.41.7-1.6-1.61.6-1.61.5-1.61.6-1.6-1.51.5-1.61.71.5-1.21.61.20.8
Delay disc. indifference point, 8s delay2.02.13.01.7-1.2-1.5-1.51.31.51.61.31.7-1.6-1.51.5-1.61.4-1.51.5-1.7-1.41.1-1.51.71.4-0.81.21.51.0
Indifference point function ln k0.10.20.70.00.0-0.5-0.20.30.00.40.50.2-0.3-0.10.1-0.20.7-0.10.30.0-0.50.4-0.4-0.00.4-0.6-0.8-0.40.4
Indifference point function log k0.10.20.70.00.0-0.5-0.20.30.00.40.50.2-0.3-0.10.1-0.20.7-0.10.30.0-0.50.4-0.4-0.00.4-0.6-0.8-0.40.4
Patch foraging total patch changes 0 sec1.42.23.0-1.71.71.61.5-1.5-1.5-1.5-1.6-1.51.61.2-1.21.5-1.71.5-1.61.21.7-1.71.4-1.3-1.51.6-1.3-1.2-1.2
Patch foraging total patch changes 12 sec0.60.81.8-1.30.61.21.0-1.0-0.8-1.0-1.0-0.91.10.6-0.60.9-1.30.8-1.10.71.1-0.70.9-0.6-0.91.20.2-0.4-0.5
Patch foraging total patch changes 18 sec2.83.55.8-2.21.42.21.7-1.9-1.8-2.0-2.1-1.81.91.8-1.81.9-2.41.8-1.91.42.4-1.92.2-1.5-2.22.3-0.7-1.3-1.5
Patch foraging total patch changes 24 sec2.83.45.7-2.41.62.02.0-1.9-1.9-1.9-2.0-2.02.01.8-1.81.9-2.11.9-2.01.81.9-1.81.9-1.7-1.91.8-1.3-1.3-1.1
Patch foraging total patch changes 6 sec0.10.21.2-0.40.60.50.4-0.3-0.2-0.3-0.4-0.20.4-0.00.00.1-0.50.2-0.5-0.30.4-0.40.30.2-0.31.10.10.60.1
Patch foraging time to switch 0 sec0.20.30.90.5-0.7-0.7-0.60.80.50.50.90.4-0.4-0.50.5-0.50.5-0.50.4-0.3-0.70.9-0.50.20.5-0.90.20.00.9
Patch foraging water rate 0 sec0.30.51.3-0.90.50.80.6-0.7-0.6-0.6-0.9-0.60.60.5-0.50.7-0.60.6-0.60.80.9-0.80.7-0.6-0.70.4-0.2-0.8-1.1
Patch foraging water rate 12 sec0.40.60.9-0.90.90.60.9-0.7-0.8-0.9-0.7-0.90.80.9-0.90.7-0.40.8-0.80.80.5-0.80.7-0.8-0.70.5-1.0-0.3-0.3
Patch foraging water rate 18 sec0.40.63.9-1.01.3-0.20.4-0.5-0.6-0.3-0.4-0.50.20.3-0.30.4-0.10.5-0.20.70.2-0.80.0-0.70.0-0.4-2.0-1.8-1.1
Patch foraging water rate 24 sec0.81.12.3-1.31.40.80.9-1.1-1.1-1.1-1.0-1.00.91.0-1.01.0-0.91.0-0.91.01.1-1.21.0-1.0-1.00.6-1.2-1.5-1.3
Patch foraging water rate 6 sec0.40.61.7-0.9-0.00.80.9-0.6-0.7-0.7-0.8-0.60.80.9-0.90.7-0.40.7-0.70.60.9-0.70.7-0.4-0.70.7-0.2-0.9-1.3
Seeking ratio, delayed vs. immediate footshock1.92.24.12.0-0.7-1.7-1.61.21.61.71.21.7-1.7-1.31.3-1.71.5-1.51.7-1.8-1.50.8-1.41.61.5-0.90.81.81.0
Distance traveled before self-admin0.30.31.6-0.31.20.00.10.2-0.3-0.1-0.4-0.40.00.6-0.60.4-0.20.4-0.00.70.4-0.70.4-0.7-0.4-0.6-0.6-1.3-0.7
Distance traveled after self-admin0.40.52.90.7-1.7-0.4-0.61.10.60.50.80.5-0.5-0.20.2-0.40.5-0.50.5-0.2-0.61.0-0.50.40.4-0.81.10.20.5
Extensor digitorum longus weight0.10.51.31.1-0.4-0.8-0.70.70.70.80.70.6-0.7-0.70.7-0.60.6-0.70.7-0.3-0.90.7-0.80.40.8-1.10.40.70.7
Bone: elastic displacement0.20.21.8-0.7-0.10.30.3-0.2-0.2-0.3-0.4-0.30.30.2-0.20.5-0.50.3-0.30.70.5-0.30.3-0.5-0.3-0.40.0-1.4-1.0
Bone: elastic work1.01.35.4-1.50.31.01.0-1.0-1.0-0.8-1.3-0.90.91.0-1.01.1-1.01.0-0.81.41.3-0.80.8-1.0-0.80.1-0.5-2.3-2.2
Bone: endosteal estimation0.10.20.5-0.30.60.40.5-0.4-0.5-0.6-0.4-0.50.50.4-0.40.4-0.60.5-0.60.30.5-0.50.5-0.4-0.50.7-0.7-0.3-0.1
Bone: endosteal perimeter0.92.02.81.5-1.1-1.7-1.51.51.41.41.71.4-1.4-1.51.5-1.51.5-1.41.4-1.5-1.51.5-1.51.31.5-1.20.60.51.0
Epididymis fat weight0.40.91.9-0.91.40.70.9-1.3-1.0-0.7-1.0-0.80.70.8-0.80.8-0.90.9-0.70.80.9-1.30.8-0.8-0.70.8-1.2-1.3-1.0
Delta time in closed arm before/after self-admin0.10.10.50.70.5-0.4-0.30.50.20.20.10.3-0.4-0.30.3-0.40.3-0.30.4-0.5-0.3-0.3-0.30.30.30.0-0.20.4-0.1
Delta time in open arm before/after self-admin0.30.31.2-0.5-1.10.80.4-0.6-0.3-0.4-0.2-0.30.50.6-0.60.4-0.50.3-0.50.30.50.40.4-0.1-0.40.60.7-0.1-0.1
Diff in mean of infusions in LGA sessions0.10.10.8-0.1-0.3-0.2-0.10.00.10.00.2-0.1-0.0-0.20.20.10.2-0.10.10.4-0.20.3-0.2-0.30.2-0.90.1-0.7-0.2
Delay discount exponential model param2.62.73.6-1.91.51.61.7-1.3-1.7-1.8-1.5-1.91.71.7-1.71.8-1.61.7-1.71.91.6-1.41.7-1.9-1.61.0-1.6-1.6-1.1
Extinction: sum of active levers before priming0.20.21.7-0.31.30.20.2-0.6-0.3-0.2-0.4-0.20.10.5-0.50.1-0.20.3-0.1-0.10.4-0.70.4-0.1-0.40.8-0.80.1-0.1
Active lever presses in extinction session 60.60.62.1-0.51.50.60.7-0.8-0.7-0.6-0.8-0.60.60.9-0.90.5-0.50.7-0.60.30.8-1.10.9-0.5-0.91.0-1.10.1-0.3
Bone: final force1.01.63.2-1.50.91.21.2-1.1-1.2-1.2-1.4-1.21.21.2-1.21.3-1.11.2-1.21.51.4-1.11.1-1.3-1.10.4-1.1-1.8-1.7
Bone: final moment1.32.13.9-1.71.11.31.4-1.3-1.4-1.4-1.6-1.41.41.4-1.41.5-1.21.4-1.41.81.5-1.31.3-1.6-1.30.5-1.3-2.0-1.8
Food consumed during 24 hour testing period1.72.04.7-1.72.01.11.4-1.4-1.5-1.4-1.2-1.51.41.4-1.41.4-1.41.5-1.41.51.1-1.31.3-1.6-1.31.0-2.2-1.2-0.1
Glucose0.20.31.6-0.30.40.70.6-0.5-0.6-0.6-0.5-0.50.60.6-0.60.4-0.60.5-0.60.10.3-0.40.5-0.2-0.51.3-0.41.00.5
Heart weight2.23.25.0-1.91.71.72.1-1.7-1.7-2.1-1.8-2.12.11.8-1.82.0-1.61.8-2.12.21.6-1.81.7-2.2-1.70.8-1.4-1.4-1.1
Delay discount hyperbolic model param2.52.73.6-1.91.51.61.7-1.3-1.7-1.8-1.5-1.91.71.6-1.61.8-1.61.7-1.71.91.6-1.41.7-1.9-1.61.0-1.6-1.7-1.2
Intermittent access intake day 1-15 change0.40.42.00.6-0.7-0.6-0.80.70.60.60.60.5-0.8-0.50.5-0.30.4-0.50.80.1-0.50.9-0.40.00.4-1.40.6-0.20.4
Intermittent access intake escalation0.30.31.50.5-0.5-0.5-0.70.60.50.50.50.4-0.6-0.40.4-0.20.3-0.40.70.1-0.40.9-0.2-0.00.2-1.20.5-0.20.4
Intermittent access intake escalation 20.20.20.9-0.4-0.20.20.00.1-0.2-0.2-0.1-0.40.10.4-0.40.5-0.40.3-0.10.90.10.40.4-0.8-0.4-0.80.0-0.50.3
Intermitt. access day 1 inactive lever presses0.10.10.6-0.40.8-0.20.0-0.00.00.10.3-0.10.00.1-0.1-0.10.0-0.0-0.0-0.1-0.20.1-0.2-0.00.2-0.0-0.4-0.10.6
Intermitt. access day 15 inactive lever presses0.70.72.60.5-0.7-1.1-0.80.80.90.90.90.7-0.8-0.80.8-0.71.1-0.80.8-0.4-0.70.9-1.00.51.0-1.60.3-1.0-0.5
Intermitt. access escalation Index0.10.10.70.20.40.10.30.2-0.1-0.1-0.4-0.00.10.1-0.1-0.10.10.1-0.2-0.30.1-0.8-0.10.20.10.6-0.30.4-0.5
Intermittent access day 1 total infusions0.00.00.2-0.10.4-0.0-0.1-0.10.00.10.00.0-0.20.0-0.0-0.10.0-0.00.1-0.1-0.1-0.2-0.10.10.10.2-0.20.30.3
Intermittent access day 15 total infusions0.10.20.60.40.2-0.3-0.60.30.40.40.30.3-0.6-0.30.3-0.20.2-0.30.7-0.1-0.40.4-0.20.10.2-0.50.30.50.8
Intermittent access terminal intake (last 3 days)0.10.10.60.00.4-0.2-0.40.20.10.20.10.1-0.5-0.10.1-0.1-0.0-0.10.5-0.0-0.20.10.0-0.0-0.0-0.2-0.20.50.8
Intermittent access total infusions0.20.20.60.30.4-0.5-0.70.30.40.50.40.4-0.8-0.40.4-0.40.3-0.40.8-0.4-0.40.3-0.30.30.3-0.40.10.50.7
Intermittent access day 1 locomotion0.30.33.10.1-0.1-0.3-0.40.20.30.20.70.3-0.4-0.30.3-0.40.4-0.40.4-0.5-0.80.6-0.40.40.40.10.21.41.8
Intermittent access day 15 total locomotion0.60.73.70.6-0.2-0.7-0.80.70.60.61.00.7-0.8-0.70.7-0.80.6-0.70.8-1.0-1.00.7-0.50.70.5-0.10.11.61.9
Intermittent access total locomotion1.11.34.01.0-0.1-1.1-1.20.81.01.01.21.1-1.3-1.01.0-1.20.9-1.01.3-1.4-1.31.0-0.91.10.9-0.30.41.82.0
Intermittent access standard deviation0.40.41.7-1.00.20.60.2-0.2-0.4-0.6-0.1-0.70.40.7-0.70.9-0.70.6-0.41.30.50.60.7-1.1-0.7-0.70.1-1.10.2
Left kidney weight0.51.44.3-0.81.61.31.6-1.5-1.4-1.2-1.2-1.11.11.4-1.40.9-0.91.2-1.10.60.7-1.00.9-0.6-0.92.1-1.41.30.6
Right kidney weight0.20.52.20.11.30.60.7-1.0-0.7-0.5-0.7-0.40.30.7-0.70.3-0.50.6-0.20.10.2-0.60.4-0.1-0.41.4-0.91.50.8
Cocaine induced anxiety0.50.61.20.8-0.6-0.9-0.90.80.80.90.90.7-0.8-0.80.8-0.70.7-0.80.8-0.5-0.91.0-0.70.50.7-1.10.40.50.8
Post-drug Anxiety0.40.40.90.7-0.2-0.8-0.60.70.70.70.70.6-0.5-0.70.7-0.60.7-0.60.5-0.5-0.90.6-0.70.40.7-0.80.20.90.9
Baseline Anxiety0.10.20.30.4-0.0-0.4-0.30.50.40.40.30.4-0.3-0.50.5-0.50.5-0.40.3-0.5-0.40.1-0.50.50.5-0.20.20.30.1
Tail length6.018.122.8-4.84.24.74.4-4.5-4.4-4.6-4.4-4.44.44.4-4.44.5-4.64.4-4.44.24.5-4.24.5-4.2-4.54.1-3.1-2.2-2.2
Length with tail8.731.938.5-6.25.56.15.9-5.9-5.8-6.0-6.0-5.95.95.8-5.85.9-5.95.9-5.95.75.9-5.85.8-5.6-5.85.1-4.5-3.6-3.7
Length without tail6.714.618.2-3.93.83.93.9-4.0-3.9-3.8-4.3-3.93.83.8-3.84.0-3.83.9-3.83.94.1-4.13.8-3.8-3.83.0-3.2-3.4-3.5
Times rat made contact with spout0.30.40.9-0.51.00.50.6-0.6-0.6-0.7-0.4-0.70.70.6-0.60.6-0.60.6-0.70.60.4-0.60.6-0.8-0.60.4-0.9-0.10.3
Lifetime Intake0.20.21.00.20.5-0.4-0.60.30.40.40.50.4-0.7-0.40.4-0.40.3-0.40.7-0.4-0.50.4-0.30.30.3-0.20.00.71.0
Liver weight, left0.10.11.3-0.00.30.10.0-0.0-0.1-0.2-0.1-0.00.10.1-0.1-0.2-0.20.0-0.2-0.60.1-0.40.20.3-0.21.0-0.11.10.6
Liver weight, right1.11.73.0-1.41.71.31.4-1.6-1.4-1.2-1.5-1.21.21.5-1.51.2-1.31.3-1.20.91.2-1.61.2-1.0-1.21.7-1.5-0.4-0.6
Locomotor activity5.89.214.5-3.83.03.23.0-3.0-3.3-3.4-3.0-3.23.03.2-3.23.3-3.13.2-2.93.23.0-2.93.1-3.2-3.12.6-2.6-2.4-1.4
Locomotor testing distance5.69.415.7-4.03.03.13.1-3.1-3.4-3.5-2.8-3.33.03.3-3.33.2-3.03.2-3.03.22.9-2.73.2-3.2-3.22.7-3.0-2.3-0.9
Locomotor testing rearing0.40.61.0-1.01.00.70.7-0.7-0.8-1.0-0.6-0.90.80.8-0.80.8-0.70.8-0.80.80.7-0.80.9-1.0-1.00.6-0.8-0.30.2
Locomotion in novel chamber0.10.10.40.4-0.0-0.3-0.5-0.10.30.50.30.4-0.5-0.40.4-0.20.2-0.30.5-0.1-0.10.4-0.20.10.2-0.70.5-0.3-0.1
Locomotion in novel chamber post-restriction0.81.01.7-1.31.11.11.0-1.2-0.9-0.9-1.0-0.91.11.3-1.30.9-1.00.9-1.10.71.1-0.71.1-0.7-1.21.3-0.6-0.5-0.2
Fecal boli incidents, locomotor time 10.60.61.9-0.70.80.80.7-0.7-0.6-0.6-1.0-0.80.70.7-0.70.8-0.70.7-0.70.91.0-0.80.7-0.7-0.70.4-0.3-1.0-1.4
Change in fecal boli incidents, locomotor task0.10.10.5-0.20.70.10.2-0.4-0.3-0.3-0.2-0.00.10.1-0.10.1-0.20.2-0.1-0.00.3-0.30.2-0.1-0.10.4-0.4-0.4-0.2
Time >=10cm from walls, locomotor time 10.30.30.80.8-0.5-0.4-0.40.90.40.20.60.5-0.4-0.40.4-0.60.6-0.50.4-0.8-0.50.2-0.50.70.50.10.20.80.3
Bouts of movement, locomotor time 10.00.00.5-0.1-0.70.20.00.1-0.1-0.2-0.1-0.10.00.1-0.10.1-0.00.0-0.00.10.00.30.1-0.0-0.10.00.50.1-0.0
Total resting periods, locomotor time 10.00.00.4-0.2-0.70.20.0-0.0-0.1-0.2-0.2-0.10.00.0-0.00.1-0.10.1-0.00.10.10.10.1-0.1-0.10.00.3-0.0-0.1
Rest time, locomotor task time 10.40.40.80.60.1-0.8-0.80.30.60.80.50.7-0.9-0.80.8-0.70.7-0.60.9-0.8-0.70.2-0.60.60.6-0.40.10.80.8
Distance moved, locomotor task time 11.61.83.9-1.81.01.31.4-1.0-1.3-1.3-1.1-1.51.51.3-1.31.4-1.31.3-1.41.51.5-0.81.2-1.4-1.20.7-1.0-2.0-1.5
Vertical activity count, locomotor time 10.60.61.1-0.90.40.90.9-0.6-0.8-1.0-0.5-0.91.00.9-0.90.8-0.80.8-1.00.80.8-0.30.7-0.7-0.60.5-0.5-1.0-0.9
Time >=10cm from walls, locomotor time 21.61.72.9-1.31.71.31.3-1.4-1.3-1.4-1.4-1.31.41.3-1.31.3-1.11.3-1.41.21.5-1.51.1-1.2-1.21.1-1.1-0.9-1.5
Bouts of movement, locomotor time 20.20.21.6-0.50.40.20.2-0.6-0.3-0.2-0.5-0.30.10.2-0.20.4-0.10.3-0.00.60.6-0.30.1-0.4-0.3-0.2-0.4-1.3-1.2
Total resting periods, locomotor time 20.10.11.2-0.30.2-0.0-0.0-0.3-0.00.1-0.30.0-0.2-0.10.10.10.10.10.30.30.3-0.1-0.1-0.1-0.0-0.4-0.2-1.1-1.0
Rest time, locomotor task time 20.00.00.2-0.1-0.5-0.0-0.2-0.10.10.2-0.10.3-0.3-0.10.1-0.10.0-0.10.3-0.20.10.20.20.2-0.00.10.2-0.4-0.1
Distance moved, locomotor task time 20.80.91.8-1.31.20.81.0-0.8-0.9-1.0-0.7-1.21.11.0-1.01.0-0.90.9-1.11.10.8-0.90.6-1.1-0.80.4-1.0-0.6-0.5
Vertical activity count, locomotor time 20.10.10.2-0.50.30.10.3-0.0-0.2-0.40.1-0.40.40.2-0.20.1-0.10.1-0.40.2-0.1-0.1-0.1-0.2-0.00.1-0.30.40.2
Light reinforcement 10.61.12.6-1.61.60.91.0-1.0-1.1-1.1-0.9-1.00.91.1-1.10.9-0.91.0-0.90.80.8-1.00.8-0.9-0.81.0-1.5-0.9-0.2
Light reinforcement 20.20.30.80.40.5-0.6-0.10.10.20.60.30.5-0.4-0.40.4-0.70.8-0.40.4-0.9-0.7-0.0-0.70.70.70.3-0.70.90.5
Bone: marrow area0.10.30.5-0.30.70.50.5-0.5-0.5-0.6-0.4-0.60.60.5-0.50.5-0.60.5-0.60.30.6-0.60.6-0.4-0.60.7-0.7-0.3-0.1
Bone: maximum diameter0.30.61.60.8-1.0-0.8-0.80.80.80.80.70.7-0.8-0.80.8-0.70.9-0.80.8-0.4-0.70.8-0.80.50.8-1.30.8-0.3-0.2
Bone: maximum force0.81.42.8-1.31.01.11.1-1.1-1.2-1.2-1.3-1.11.21.1-1.11.2-1.11.2-1.21.31.4-1.11.1-1.2-1.10.6-1.1-1.6-1.7
Bone: maximum moment1.01.72.8-1.41.11.21.2-1.2-1.3-1.3-1.4-1.31.31.2-1.21.3-1.21.3-1.31.41.4-1.21.2-1.3-1.20.6-1.3-1.7-1.7
Mean time between licks in bursts0.91.21.81.2-1.1-1.1-1.11.11.11.11.21.0-1.1-1.11.1-1.01.0-1.11.1-0.8-1.31.2-1.10.81.1-1.31.20.91.0
Mean num. licks in bursts0.40.51.6-0.61.00.80.8-0.8-0.7-0.7-0.7-0.60.70.8-0.80.6-0.90.7-0.70.40.6-0.80.7-0.4-0.71.3-0.60.60.3
Cd content in liver2.42.63.6-1.71.71.61.5-1.5-1.5-1.8-1.5-1.81.81.5-1.51.8-1.81.6-1.81.71.7-1.81.8-1.9-1.81.1-1.1-1.2-0.7
Co content in liver0.10.21.5-0.0-0.20.20.2-0.1-0.2-0.2-0.4-0.20.20.2-0.20.4-0.20.2-0.20.50.5-0.30.3-0.4-0.3-0.4-0.1-1.0-1.2
Cu content in liver4.25.18.7-3.02.52.22.3-2.2-2.4-2.3-2.1-2.32.32.2-2.22.3-2.42.3-2.32.02.3-2.22.3-2.2-2.32.2-2.3-2.2-1.1
Fe content in liver1.62.03.4-1.10.71.61.2-1.1-1.1-1.6-1.6-1.41.61.2-1.21.6-1.51.3-1.61.51.8-1.61.6-1.5-1.60.8-0.1-1.4-1.8
K content in liver0.70.72.8-0.7-0.21.30.9-0.9-0.8-0.7-1.3-0.60.71.0-1.00.8-0.70.7-0.70.81.1-0.50.7-0.3-0.70.80.7-0.4-1.7
Mg content in liver0.20.21.90.2-1.10.50.2-0.2-0.00.1-0.60.2-0.10.3-0.30.10.1-0.10.10.10.30.3-0.10.40.10.11.40.3-1.3
Mn content in liver0.70.81.8-0.80.11.31.0-1.0-0.9-0.7-1.2-0.60.81.1-1.10.8-0.80.8-0.70.61.1-0.70.8-0.3-0.81.30.3-0.2-1.3
Na content in liver0.30.41.1-0.7-0.20.90.4-0.4-0.3-0.7-0.8-0.40.60.4-0.40.5-0.70.4-0.70.40.9-0.50.6-0.2-0.60.60.8-0.3-1.1
Rb content in liver1.21.42.4-1.21.01.10.8-0.8-0.9-1.4-1.1-1.31.30.9-0.91.3-1.41.1-1.41.31.5-1.41.5-1.5-1.60.4-0.7-1.5-0.9
Se content in liver0.10.11.10.3-0.70.30.1-0.20.10.0-0.30.10.00.0-0.00.10.1-0.00.00.20.10.1-0.20.20.2-0.11.0-0.0-0.9
Sr content in liver0.10.10.5-0.10.40.00.3-0.3-0.20.1-0.0-0.1-0.00.3-0.30.0-0.00.20.10.1-0.10.1-0.10.00.10.3-0.7-0.20.2
Zn content in liver4.75.26.3-2.52.22.42.4-2.4-2.5-2.3-2.4-2.32.32.4-2.42.3-2.32.4-2.32.12.5-2.32.3-2.0-2.32.3-2.2-2.1-1.9
Bone: minimum diameter0.20.40.70.5-0.3-0.9-0.70.70.60.70.70.6-0.7-0.70.7-0.60.8-0.60.7-0.5-0.60.6-0.70.50.7-0.8-0.1-0.30.1
Time in familiar zone, hab. session 11.00.91.90.9-0.7-1.1-1.21.11.10.91.00.9-0.9-1.21.2-0.90.9-1.00.9-0.7-0.90.8-0.90.60.9-1.41.10.10.3
Time in novel zone, hab. session 10.40.41.4-0.60.70.40.7-0.6-0.7-0.6-0.3-0.70.60.7-0.70.5-0.60.6-0.60.60.3-0.40.5-0.6-0.50.6-1.20.20.6
Total zone transitions, hab. session 10.60.82.2-0.81.10.91.1-1.1-1.1-0.8-0.8-0.80.81.1-1.10.7-0.80.9-0.80.50.6-0.70.8-0.5-0.81.5-1.20.50.4
Total locomotion distance, hab. session 10.20.30.7-0.40.60.60.6-0.7-0.6-0.5-0.5-0.50.40.6-0.60.4-0.50.5-0.40.30.3-0.50.4-0.3-0.40.8-0.60.40.1
Locomotion velocity, hab. session 10.20.31.1-0.50.40.70.7-0.7-0.7-0.5-0.7-0.40.40.7-0.70.4-0.50.5-0.40.30.5-0.50.4-0.2-0.41.1-0.30.3-0.3
Time in familiar zone, hab. session 20.40.41.70.7-1.3-0.4-0.60.60.70.50.20.6-0.5-0.60.6-0.30.5-0.60.6-0.1-0.30.6-0.50.40.5-1.11.3-0.2-0.9
Time in novel zone, hab. session 20.20.22.3-0.41.0-0.20.1-0.0-0.2-0.20.3-0.30.20.1-0.1-0.0-0.20.2-0.2-0.2-0.2-0.20.2-0.2-0.20.5-1.10.51.5
Total zone transitions, hab. session 20.10.20.5-0.20.50.30.5-0.5-0.4-0.2-0.2-0.30.30.5-0.50.2-0.10.3-0.20.1-0.1-0.10.1-0.1-0.10.7-0.60.70.7
Total locomotion distance, hab. session 20.20.30.8-0.60.40.70.7-0.7-0.6-0.5-0.6-0.40.50.7-0.70.4-0.50.5-0.40.30.5-0.40.4-0.2-0.40.9-0.20.1-0.3
Locomotion velocity, hab. session 20.10.20.7-0.40.10.60.5-0.5-0.4-0.4-0.5-0.30.30.5-0.50.3-0.30.3-0.30.20.3-0.30.30.0-0.30.80.20.4-0.3
Novel to familiar place preference ratio0.91.04.6-1.01.31.01.0-1.0-1.0-1.1-0.8-0.80.90.9-0.90.6-1.00.9-1.00.10.8-1.00.9-0.3-0.92.1-1.00.70.5
Novelty place preference0.90.94.7-1.01.31.01.0-0.9-1.0-1.1-0.8-0.80.90.9-0.90.6-1.00.8-1.0-0.00.8-1.00.9-0.3-0.92.2-1.00.80.5
Time in novel zone, NPP test1.21.24.7-1.21.51.11.1-1.1-1.1-1.2-0.9-1.01.11.0-1.00.7-1.11.0-1.20.20.9-1.21.1-0.5-1.12.2-1.30.60.6
Total zone transitions, NPP test2.13.05.9-1.62.01.92.1-2.2-2.0-1.6-1.8-1.61.62.2-2.21.6-1.61.8-1.61.41.4-1.51.6-1.3-1.62.4-1.90.20.1
Total locomotion distance, NPP test0.81.21.8-1.21.21.21.3-1.3-1.2-1.0-1.2-1.01.01.3-1.31.1-1.01.1-0.91.00.9-1.01.0-0.9-1.01.3-1.1-0.3-0.5
Locomotion velocity, NPP test0.91.22.2-1.11.11.41.3-1.4-1.3-1.1-1.3-1.01.01.3-1.31.1-1.01.2-1.01.01.1-1.01.0-0.8-1.01.5-0.9-0.2-0.7
Intraocular pressure1.01.42.8-1.11.71.11.1-1.0-1.1-1.4-1.0-1.21.31.2-1.21.1-1.41.1-1.40.81.2-1.41.4-1.2-1.41.3-1.1-0.4-0.2
Delta distance traveled before/after self-admin0.60.73.90.7-2.0-0.4-0.50.50.70.60.80.6-0.4-0.80.8-0.70.7-0.70.4-0.8-0.81.2-0.80.90.7-0.11.11.20.9
Delta ambulatory time before/after self-admin0.20.22.5-0.2-1.60.60.5-0.3-0.3-0.50.0-0.40.60.2-0.20.2-0.30.2-0.60.1-0.10.40.1-0.0-0.10.70.30.70.7
Parametrial fat weight0.71.42.9-1.71.01.21.2-1.0-1.4-1.4-0.8-1.31.21.3-1.31.1-1.21.3-1.21.01.0-0.71.2-1.1-1.21.5-1.6-0.70.5
Pavlov. Cond. lever latency4.76.08.6-2.62.92.42.5-2.5-2.5-2.7-2.2-2.72.72.4-2.42.5-2.72.5-2.72.42.3-2.52.6-2.6-2.62.2-2.5-1.1-0.3
Pavlov. Cond. magazine entry latency5.97.713.02.8-3.6-2.7-2.92.92.92.92.72.9-2.9-2.72.7-2.82.9-2.92.9-2.5-2.63.0-2.82.82.8-2.83.21.20.8
Pavlov. Cond. change in total contacts1.51.64.71.5-1.9-1.0-1.41.31.41.30.91.4-1.3-1.31.3-1.21.3-1.31.3-1.2-0.81.0-1.21.41.2-1.22.20.1-0.9
Pavlov. Cond. index score5.97.512.92.9-3.6-2.6-2.82.92.92.82.52.9-2.8-2.72.7-2.72.9-2.92.9-2.5-2.52.9-2.82.82.8-2.73.31.20.4
Pavlov. Cond. latency score5.87.412.82.9-3.6-2.5-2.82.82.82.82.42.9-2.8-2.72.7-2.72.9-2.82.9-2.5-2.52.8-2.82.92.8-2.53.31.30.3
Pavlov. Cond. lever contacts2.73.24.91.9-2.2-1.7-1.81.81.82.01.62.0-2.0-1.71.7-1.92.0-1.92.0-1.8-1.71.8-1.92.01.9-1.51.90.80.1
Pavlov. Cond. magazine entry number6.88.412.5-3.03.52.93.0-3.1-3.0-3.0-2.9-3.13.02.9-2.92.9-3.13.0-3.02.82.8-3.12.9-3.0-2.92.8-3.2-1.5-1.1
Pavlov. Cond. intertrial magazine entries0.40.40.6-0.50.70.70.7-0.7-0.7-0.6-0.6-0.70.70.7-0.70.7-0.70.7-0.70.60.7-0.60.7-0.7-0.80.7-0.7-0.1-0.1
Pavlov. Cond. lever-magazine prob. diff.5.26.411.42.6-3.4-2.4-2.62.72.72.62.32.7-2.6-2.52.5-2.52.8-2.62.7-2.2-2.32.7-2.62.52.6-2.73.10.80.2
Pavlov. Cond. response bias6.37.610.72.7-3.3-2.8-2.92.92.92.92.82.9-2.9-2.82.8-2.83.0-2.93.0-2.5-2.72.9-2.82.72.8-2.82.91.00.9
Pavlov. Cond. lever latency0.60.81.21.0-0.6-1.1-1.00.90.90.81.00.8-0.9-1.01.0-0.91.1-0.90.9-1.0-0.90.8-0.80.80.8-0.60.20.70.8
Pavlov. Cond. magazine entry latency0.10.10.4-0.1-0.5-0.0-0.10.10.20.30.10.3-0.3-0.10.1-0.10.2-0.20.30.0-0.20.4-0.30.30.3-0.40.6-0.1-0.3
Pavlov. Cond. change in total contacts2.73.75.2-2.21.52.32.2-2.0-1.9-2.0-2.2-2.02.12.1-2.12.1-2.22.0-2.02.22.0-1.91.9-1.9-1.91.4-0.7-1.2-1.5
Pavlov. Cond. index score0.20.20.6-0.70.10.60.6-0.5-0.4-0.3-0.6-0.40.40.5-0.50.5-0.60.4-0.40.70.4-0.20.3-0.4-0.30.10.2-0.7-0.8
Pavlov. Cond. latency score0.10.20.5-0.60.00.50.5-0.5-0.4-0.2-0.6-0.30.30.5-0.50.4-0.40.4-0.30.60.4-0.20.2-0.3-0.20.00.2-0.6-0.7
Pavlov. Cond. lever contacts1.01.42.1-1.41.01.41.4-1.3-1.2-1.2-1.4-1.21.31.3-1.31.3-1.41.2-1.31.21.1-1.11.1-1.1-1.11.2-0.6-0.5-0.6
Pavlov. Cond. magazine entry number0.20.20.9-0.20.70.30.4-0.4-0.5-0.5-0.3-0.50.50.4-0.40.4-0.30.5-0.50.20.5-0.60.6-0.5-0.60.5-0.9-0.10.0
Pavlov. Cond. intertrial magazine entries0.30.40.70.8-0.8-0.7-0.90.80.70.50.60.6-0.6-0.80.8-0.70.8-0.70.6-0.8-0.40.4-0.50.60.5-0.60.70.40.0
Pavlov. Cond. lever-magazine prob. diff.0.20.20.5-0.70.10.60.6-0.5-0.4-0.3-0.6-0.40.40.5-0.50.5-0.50.4-0.30.70.3-0.20.2-0.4-0.20.00.2-0.6-0.6
Pavlov. Cond. response bias0.10.20.4-0.50.10.60.6-0.5-0.4-0.3-0.6-0.40.40.5-0.50.5-0.60.4-0.40.60.3-0.20.3-0.3-0.30.20.3-0.2-0.4
Time in closed arm before self-admin1.71.93.2-1.50.51.51.2-1.6-1.5-1.3-1.4-1.41.31.5-1.51.6-1.61.5-1.31.61.4-1.31.8-1.6-1.81.1-1.2-0.9-0.3
Time in closed arm after self-admin0.10.10.50.10.30.10.1-0.2-0.2-0.2-0.3-0.20.10.2-0.20.2-0.10.3-0.00.20.1-0.60.4-0.4-0.40.1-0.70.10.1
Time in open arm before self-admin1.11.22.11.1-0.3-1.4-1.01.31.10.91.20.9-1.0-1.21.2-1.21.4-1.11.0-1.2-1.40.7-1.41.01.4-1.10.51.10.9
Time in open arm after self-admin0.60.62.50.6-1.6-0.2-0.40.30.60.40.80.7-0.4-0.30.3-0.70.4-0.70.4-1.1-0.61.3-0.61.10.50.51.41.31.2
Bone: periosteal estimation0.10.10.7-0.20.10.20.2-0.2-0.2-0.3-0.4-0.30.30.2-0.20.3-0.20.3-0.30.40.4-0.30.2-0.3-0.2-0.1-0.2-0.8-0.9
Bone: periosteal perimeter0.91.51.91.3-1.3-1.4-1.31.41.31.31.31.3-1.3-1.41.4-1.31.4-1.31.3-1.1-1.11.3-1.31.21.3-1.41.00.10.1
Bone: post-yield work0.10.10.7-0.20.70.10.3-0.2-0.3-0.3-0.1-0.30.30.2-0.20.2-0.10.3-0.30.10.2-0.20.2-0.2-0.20.3-0.8-0.10.1
Progressive ratio test 1 active lever presses0.10.10.9-0.30.30.1-0.1-0.1-0.1-0.10.1-0.0-0.20.2-0.2-0.1-0.20.10.1-0.3-0.0-0.20.30.1-0.30.6-0.30.71.0
Progressive ratio test 1 breakpoint0.10.11.0-0.10.4-0.1-0.20.0-0.00.10.20.1-0.30.0-0.0-0.2-0.1-0.00.2-0.4-0.1-0.20.20.2-0.20.5-0.40.71.0
Progressive ratio test 1 inactive lever presses0.40.41.30.2-0.7-0.6-0.70.50.60.51.00.4-0.7-0.40.4-0.50.5-0.50.7-0.2-0.71.1-0.40.30.4-1.00.50.11.1
Progressive ratio test 2 active lever presses0.70.81.70.9-0.6-0.9-1.00.70.90.81.00.9-1.1-0.80.8-0.90.8-0.91.1-0.8-1.00.9-0.70.80.7-0.70.71.21.3
Progressive ratio test 2 breakpoint0.60.61.20.9-0.6-0.8-1.00.60.80.80.80.8-1.0-0.70.7-0.80.7-0.81.0-0.7-0.90.7-0.60.70.6-0.70.61.11.0
Progressive ratio test 2 inactive lever presses1.51.73.91.2-1.1-1.5-1.61.01.41.51.61.2-1.5-1.21.2-1.11.3-1.31.6-0.7-1.51.7-1.20.81.2-2.01.00.71.4
Incentive Sensitization - Responses1.51.62.61.3-1.2-1.4-1.31.11.31.31.21.2-1.3-1.31.3-1.21.4-1.31.3-1.0-1.41.1-1.31.01.3-1.61.11.00.8
Incentive Sensitization - Breakpoint1.51.52.61.3-1.2-1.4-1.31.11.31.21.21.2-1.3-1.31.3-1.21.4-1.31.3-0.9-1.41.1-1.31.01.3-1.61.10.90.7
Sum of active levers in priming session hrs 5-60.40.40.8-0.90.70.70.7-0.8-0.5-0.6-0.4-0.60.70.6-0.60.5-0.60.5-0.70.30.5-0.20.8-0.4-0.70.9-0.30.50.6
Progressive ratio3.74.36.7-2.12.62.12.0-2.6-2.1-1.9-2.1-1.92.12.2-2.22.0-2.32.1-2.11.82.1-2.22.2-1.9-2.32.2-2.2-1.1-0.4
Food seeking constrained by brief footshock0.60.71.81.3-0.2-0.9-0.90.60.90.90.60.8-0.9-1.01.0-0.80.8-0.80.9-0.7-1.00.2-0.80.70.9-0.80.41.30.5
Seeking ratio, punishment vs. effort5.16.28.02.8-2.3-2.7-2.52.82.62.42.42.4-2.6-2.72.7-2.52.7-2.52.6-2.1-2.72.3-2.72.22.7-2.82.11.81.0
Retroperitoneal fat weight0.51.82.8-1.61.41.31.4-1.6-1.5-1.3-1.5-1.41.31.1-1.11.2-1.31.4-1.31.11.3-1.71.0-1.1-1.01.5-1.6-1.1-1.2
Reaction time number correct0.30.41.60.1-0.4-0.8-0.80.60.50.40.90.4-0.7-0.50.5-0.60.6-0.60.7-0.5-0.80.7-0.50.40.5-0.6-0.20.61.3
Reaction time mean minus median0.10.11.1-0.00.20.10.10.1-0.2-0.30.2-0.1-0.00.3-0.30.0-0.00.10.1-0.0-0.20.10.1-0.0-0.10.4-0.40.71.0
Reaction time mean minus median AUC0.20.31.3-0.31.10.40.4-0.3-0.5-0.6-0.2-0.40.30.6-0.60.3-0.40.4-0.30.20.1-0.50.5-0.4-0.50.8-0.90.91.0
Reaction time num false alarms0.30.41.70.7-0.6-0.5-0.80.60.60.40.60.6-0.6-0.80.8-0.70.5-0.60.5-0.8-0.60.5-0.50.70.4-0.20.61.30.8
Reaction time num false alarms AUC0.10.21.30.3-0.2-0.3-0.40.30.30.10.40.3-0.3-0.60.6-0.40.2-0.40.2-0.6-0.40.2-0.30.50.20.20.21.20.9
Reaction time trials correct on left0.30.41.60.1-0.4-0.8-0.80.60.50.40.90.4-0.7-0.50.5-0.60.6-0.60.7-0.5-0.80.7-0.50.40.5-0.6-0.20.61.3
Reaction time trials on left0.30.41.90.2-0.4-0.9-0.90.60.50.40.90.4-0.7-0.50.5-0.60.6-0.60.7-0.6-0.90.7-0.50.40.5-0.6-0.20.71.4
Reaction time mean0.00.00.2-0.40.00.10.00.1-0.2-0.40.2-0.10.00.1-0.10.1-0.20.1-0.00.1-0.00.00.1-0.1-0.10.2-0.0-0.10.4
Reaction time mean AUC0.00.00.4-0.20.2-0.1-0.10.2-0.1-0.30.3-0.1-0.10.0-0.0-0.0-0.10.00.1-0.1-0.1-0.00.0-0.0-0.00.3-0.30.20.7
Median of all reaction times0.00.00.3-0.5-0.10.10.00.1-0.1-0.40.1-0.20.1-0.10.10.1-0.20.1-0.10.10.0-0.00.1-0.1-0.10.10.1-0.30.2
Reaction time omissions0.50.62.50.5-0.7-0.8-0.91.00.80.41.20.5-0.7-0.80.8-0.70.5-0.70.6-0.8-0.90.8-0.60.50.6-0.60.40.91.6
Reaction time false alarm rate0.10.10.50.5-0.2-0.1-0.20.20.30.20.00.3-0.2-0.40.4-0.30.1-0.30.1-0.4-0.10.0-0.20.40.10.20.50.70.1
Reaction time premature initiation rate1.52.04.5-2.11.31.41.6-1.4-1.6-1.7-1.1-1.51.61.2-1.21.4-1.31.4-1.61.31.3-1.01.3-1.3-1.31.4-1.3-1.5-0.6
Reaction time premature initiations0.71.03.3-1.80.90.91.0-0.9-1.2-1.3-0.5-1.11.10.8-0.80.9-0.81.0-1.10.90.7-0.50.8-0.9-0.80.9-1.3-1.00.1
Std. dev. reaction times0.10.21.0-0.20.50.30.2-0.1-0.4-0.60.0-0.30.10.5-0.50.2-0.40.3-0.10.00.0-0.20.4-0.2-0.40.8-0.40.81.0
Reaction time trials completed0.30.41.90.2-0.4-0.9-0.90.60.50.40.90.4-0.7-0.50.5-0.60.6-0.60.7-0.6-0.90.7-0.50.40.5-0.6-0.20.71.4
Reaction time trials AUC0.40.52.10.2-0.5-0.9-0.90.70.60.51.00.5-0.8-0.60.6-0.70.7-0.70.8-0.7-0.90.8-0.60.40.6-0.7-0.10.91.5
Run reversals in cocaine runway, females1.81.72.81.4-1.0-1.6-1.31.51.41.61.41.3-1.2-1.51.5-1.31.7-1.31.3-1.2-1.31.2-1.51.21.5-1.60.70.10.1
Run reversals in cocaine runway, males0.30.30.8-0.9-0.70.60.6-0.4-0.4-0.8-0.0-0.70.80.4-0.40.6-0.30.4-0.70.80.20.40.2-0.6-0.3-0.10.2-0.50.1
Latency to leave start box in cocaine runway0.20.20.6-0.8-0.10.60.6-0.5-0.4-0.7-0.3-0.50.70.5-0.50.5-0.60.4-0.70.60.40.10.4-0.4-0.30.20.2-0.4-0.2
Latency to leave start box in cocaine runway, F1.21.32.8-1.70.21.21.1-0.9-1.0-1.4-0.9-1.31.31.3-1.31.3-1.21.1-1.31.61.1-0.41.1-1.3-1.20.2-0.2-1.5-0.8
Latency to leave start box in cocaine runway, M0.50.51.10.7-0.5-0.6-0.50.30.70.70.70.8-0.6-0.70.7-0.80.6-0.70.6-1.1-0.60.7-0.81.00.80.00.60.70.4
Std. dev. time between licks in bursts2.63.16.01.7-1.5-2.1-1.91.91.81.92.01.7-1.9-1.91.9-1.71.9-1.81.9-1.3-1.91.9-1.91.31.9-2.41.00.20.9
Total sessions with >9 infusions0.20.21.9-0.41.4-0.4-0.2-0.2-0.1-0.10.3-0.2-0.3-0.20.20.10.10.10.40.3-0.2-0.20.0-0.5-0.0-0.6-1.0-0.50.5
Short access day 1 total inactive lever presses2.22.43.91.5-1.2-1.9-1.91.21.71.81.61.6-1.9-1.61.6-1.61.6-1.62.0-1.4-1.71.6-1.61.31.6-1.81.00.81.2
Short access day 10 total inactive lever presses0.10.11.20.0-0.1-0.3-0.10.30.30.30.4-0.00.1-0.10.10.00.2-0.2-0.00.4-0.30.6-0.3-0.20.3-1.10.3-0.7-0.0
Short access day 1 total infusions0.70.71.10.60.3-1.0-1.00.80.80.91.00.8-1.1-0.90.9-0.90.9-0.81.1-0.8-0.90.9-0.80.70.8-0.90.30.60.9
Short access day 10 total infusions0.10.11.7-0.11.3-0.0-0.2-0.2-0.10.0-0.2-0.1-0.30.0-0.00.0-0.10.10.3-0.10.0-0.50.1-0.1-0.10.3-0.60.30.2
Short access total infusions0.40.41.60.40.6-0.7-0.70.50.50.60.70.5-0.8-0.60.6-0.70.5-0.50.8-0.7-0.70.5-0.50.60.5-0.2-0.11.01.2
Short access day 1 locomotion0.30.34.4-0.02.1-0.3-0.2-0.30.00.10.30.0-0.4-0.00.0-0.20.1-0.00.4-0.2-0.3-0.1-0.1-0.00.10.1-0.90.71.3
Short access day 10 total locomotion0.20.21.6-0.21.20.20.1-0.5-0.3-0.3-0.1-0.10.00.2-0.20.0-0.30.2-0.1-0.30.2-0.50.30.1-0.31.0-0.80.50.6
Short access total locomotion0.40.43.5-0.01.5-0.1-0.2-0.3-0.0-0.10.40.0-0.30.1-0.1-0.2-0.1-0.00.2-0.5-0.4-0.10.10.2-0.10.8-0.71.61.9
One hour access (0.3 mA shock)0.20.33.1-0.10.5-0.1-0.40.30.10.20.40.2-0.50.0-0.0-0.30.0-0.20.5-0.4-0.50.4-0.00.20.00.4-0.21.41.8
Compulsive drug intake0.10.10.60.20.2-0.10.00.20.10.20.10.2-0.1-0.20.2-0.30.2-0.20.1-0.6-0.30.0-0.30.40.30.5-0.10.80.4
One hour access (shock baseline)0.10.11.3-0.2-0.10.1-0.30.20.1-0.00.2-0.0-0.30.1-0.10.1-0.2-0.00.30.1-0.10.50.2-0.1-0.2-0.10.30.61.1
Social response proportion0.20.31.5-1.20.00.40.5-0.1-0.4-0.6-0.1-0.60.60.3-0.30.4-0.50.4-0.70.30.5-0.30.6-0.4-0.50.5-0.4-1.0-0.0
Social responses0.30.41.4-1.20.80.60.6-0.5-0.6-0.7-0.5-0.60.60.6-0.60.5-0.60.6-0.60.30.6-0.70.6-0.3-0.60.9-0.7-0.6-0.4
Social time0.81.13.50.3-1.1-1.4-0.91.40.90.91.60.6-0.7-1.01.0-0.81.1-0.90.8-0.3-1.41.5-1.10.41.1-1.90.0-0.61.4
Soleus weight3.710.913.1-3.13.53.43.5-3.6-3.4-3.3-3.4-3.53.43.6-3.63.5-3.33.5-3.33.53.2-3.33.4-3.4-3.42.8-3.3-1.7-1.7
Bone: stiffness0.10.20.4-0.30.30.50.4-0.4-0.4-0.5-0.6-0.40.50.4-0.40.4-0.30.4-0.50.30.6-0.40.5-0.3-0.50.5-0.2-0.1-0.7
Tibialis anterior weight0.00.10.30.40.40.10.3-0.3-0.2-0.1-0.3-0.30.20.2-0.20.3-0.30.3-0.10.50.1-0.20.1-0.5-0.1-0.2-0.50.0-0.1
Time to tail flick, vehicle, before self-admin2.22.26.1-1.62.51.31.4-1.6-1.4-1.2-1.5-1.41.31.4-1.41.4-1.41.5-1.41.41.5-1.71.6-1.5-1.61.2-1.8-0.9-0.6
Time to tail flick, vehicle, after self-admin0.50.52.1-1.2-0.20.80.7-0.0-0.6-0.6-0.5-0.80.80.6-0.60.8-0.90.6-0.81.00.70.00.6-0.7-0.50.00.2-1.4-0.7
Time to tail flick, test, before self-admin0.30.31.8-0.21.0-0.30.30.1-0.0-0.10.4-0.10.3-0.30.3-0.40.3-0.1-0.4-0.7-0.6-0.4-0.30.40.30.7-0.81.31.3
Time to tail flick, test, after self-admin0.10.10.6-0.20.3-0.4-0.40.10.30.30.30.2-0.4-0.40.4-0.20.2-0.20.4-0.1-0.00.3-0.20.10.2-0.60.1-0.8-0.4
Delta time to tail flick, vehicle, before/after SA0.80.83.70.3-1.9-0.6-0.71.40.80.70.90.7-0.6-0.60.6-0.60.6-0.80.6-0.4-0.61.4-0.90.70.9-1.21.6-0.8-0.5
Delta time to tail flick, test, before/after SA0.30.21.70.2-0.1-0.1-0.60.00.30.4-0.10.4-0.7-0.20.2-0.0-0.0-0.20.70.10.40.4-0.10.10.0-0.70.6-1.3-1.2
Tibia length6.819.224.8-5.04.54.54.7-4.8-4.7-4.2-4.7-4.44.34.7-4.74.5-4.14.6-4.24.54.5-4.34.2-4.2-4.23.8-4.2-3.5-3.5
Ambulatory time before self-admin0.20.21.00.11.0-0.3-0.20.5-0.00.3-0.2-0.0-0.20.3-0.30.20.00.10.30.40.3-0.40.2-0.4-0.2-0.8-0.3-1.0-0.7
Ambulatory time after self-admin0.20.22.10.6-1.4-0.1-0.20.60.20.30.40.2-0.10.1-0.1-0.20.3-0.30.1-0.2-0.30.6-0.20.30.1-0.10.70.50.5
Bone: tissue strength3.63.56.5-2.01.42.01.8-1.9-1.8-1.8-2.1-1.81.91.8-1.82.1-1.81.9-1.82.22.2-1.71.8-2.0-1.80.9-0.9-2.4-2.5
Total heroin consumption1.11.33.3-1.80.51.21.2-1.2-1.2-1.4-0.9-1.41.31.0-1.01.3-1.01.2-1.31.41.2-0.60.9-1.2-1.10.6-0.7-1.6-0.9
Bone: trabecular number0.61.01.91.2-1.3-0.7-0.90.90.91.00.71.1-1.0-0.80.8-1.10.9-1.01.0-1.2-0.90.9-0.91.30.9-0.21.41.40.4
Bone: trabecular spacing1.31.72.9-1.71.51.11.3-1.3-1.3-1.3-1.2-1.41.31.2-1.21.4-1.11.3-1.31.61.3-1.21.3-1.5-1.20.5-1.5-1.7-1.0
Bone: trabecular thickness0.10.10.7-0.2-0.40.40.2-0.2-0.1-0.0-0.40.10.00.2-0.2-0.0-0.10.0-0.0-0.20.3-0.10.00.4-0.00.60.6-0.0-0.8
Bone: trabecular tissue density0.20.20.7-0.30.20.60.6-0.5-0.5-0.5-0.5-0.40.50.5-0.50.4-0.30.4-0.50.20.4-0.40.5-0.2-0.50.8-0.10.70.1
Water consumed over 24 hours0.10.10.50.00.3-0.3-0.00.0-0.10.10.1-0.2-0.0-0.00.00.10.10.10.10.4-0.20.1-0.1-0.40.1-0.7-0.7-0.70.1
Number of responses in last shaping day0.40.41.41.0-0.1-0.7-0.80.70.80.80.30.6-0.8-0.70.7-0.50.7-0.60.9-0.3-0.60.3-0.70.30.7-1.20.60.3-0.3