Hub : Traits : body_g : ← →

chr7:81,442,141-85,355,253

Best TWAS P=5.438581e-10 · Best GWAS P=8.877452e-12 conditioned to 2.703087e-05

Associated models

#	Tissue	Gene	Modality	RNA phenotype	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	BLA	Med30	gene expression	ENSRNOG00000004844	0.07	0.04	blup	1914	0.05	1.3e-03	-4.9	-5.3	1.1e-07	0.59	0.46	0.42	FALSE
2	BLA	Ext1	mRNA stability	ENSRNOG00000024886	0.38	0.26	blup	1844	0.29	1.2e-15	-4.3	5.2	1.7e-07	-0.56	0.37	0.63	FALSE
3	Brain	Trps1	gene expression	ENSRNOG00000024998	0.06	0.05	blup	1999	0.07	8.2e-07	-3.4	5.5	4.2e-08	-0.86	0.52	0.48	FALSE
4	Brain	Med30	mRNA stability	ENSRNOG00000004844	0.04	0.00	blup	1914	0.02	4.3e-03	-5.0	6.2	5.4e-10	-0.52	0.46	0.43	TRUE
5	Brain	Ext1	mRNA stability	ENSRNOG00000024886	0.10	0.08	blup	1844	0.09	6.9e-09	4.1	5.4	5.8e-08	-0.56	0.44	0.56	FALSE
6	LHb	Rad21	gene expression	ENSRNOG00000004420	0.22	0.11	lasso	2	0.12	1.1e-03	-4.9	-5.9	4.1e-09	0.61	0.48	0.38	FALSE
7	Liver	Med30	intron excision ratio	chr7:84012067:84015230	0.06	0.02	enet	68	0.02	1.1e-03	-4.7	-5.8	7.4e-09	0.37	0.60	0.23	FALSE
8	PL	Ext1	mRNA stability	ENSRNOG00000024886	0.27	0.02	blup	1838	0.11	1.5e-03	4.2	5.3	1.1e-07	-0.51	0.44	0.33	FALSE
9	PL2	Trps1	gene expression	ENSRNOG00000024998	0.05	0.05	top1	1	0.05	1.7e-03	-5.1	5.1	2.9e-07	-0.87	0.09	0.04	FALSE
10	PL2	Ext1	mRNA stability	ENSRNOG00000024886	0.62	0.41	enet	236	0.45	1.3e-26	-4.7	5.4	8.3e-08	-0.58	0.31	0.69	FALSE

h2: Heritability estimate for the given transcriptomic model. PP3: Posterior probability of two distinct causal variants. PP4: Posterior probability of a single shared causal variant. joint: Whether the RNA phenotype is in the joint model.