Hub : Traits : Body weight : ← →

chr7:26,902,995-30,734,621

Trait: Body weight

Best TWAS P=1.053888e-24 · Best GWAS P=5.722316e-25 conditioned to NaN

Associated models

#	Tissue	Gene	Modality	RNA phenotype	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	Adipose	Elk3	gene expression	ENSRNOG00000004367	0.11	0.05	blup	2579	0.05	2.5e-06	-7.5	7.7	1.2e-14	-0.48	0.74	0.26	FALSE
2	Adipose	Hal	gene expression	ENSRNOG00000004502	0.03	0.00	blup	2432	0.01	6.9e-02	-8.5	-8.5	1.5e-17	0.53	0.28	0.38	FALSE
3	Adipose	Vezt	gene expression	ENSRNOG00000006514	0.11	0.08	top1	1	0.08	3.2e-09	-6.3	-6.3	2.5e-10	0.67	1.00	0.00	FALSE
4	Adipose	Ndufa12	gene expression	ENSRNOG00000007407	0.34	0.19	lasso	16	0.20	1.0e-21	-7.3	-7.4	1.7e-13	0.73	1.00	0.00	FALSE
5	Adipose	Tmcc3	gene expression	ENSRNOG00000007713	0.11	0.02	blup	2421	0.04	1.1e-05	-6.9	-5.8	8.2e-09	0.42	0.91	0.02	FALSE
6	Adipose	Fgd6	gene expression	ENSRNOG00000054515	0.07	0.01	enet	82	0.04	1.4e-05	-6.7	5.9	3.7e-09	-0.50	0.75	0.10	FALSE
7	Adipose	Tmcc3	isoform ratio	ENSRNOT00000010316	0.16	0.02	top1	1	0.02	1.4e-03	5.3	5.3	9.2e-08	-0.15	0.07	0.03	FALSE
8	Adipose	Cep83	intron excision ratio	chr7:29322957:29325469	0.03	0.01	blup	2703	0.02	1.8e-03	-6.9	-6.7	2.4e-11	0.74	0.55	0.32	TRUE
9	Adipose	Vezt	mRNA stability	ENSRNOG00000006514	0.07	0.04	blup	2570	0.06	5.0e-07	-8.0	-8.3	1.4e-16	0.71	0.74	0.26	FALSE
10	BLA	AABR07056633.1	alternative TSS	ENSRNOT00000094647	0.19	0.12	lasso	27	0.12	3.4e-07	-5.3	5.3	1.5e-07	-0.26	1.00	0.00	FALSE
11	BLA	Ntn4	gene expression	ENSRNOG00000005573	0.06	0.02	blup	2475	0.03	8.1e-03	1.2	7.3	3.3e-13	-0.60	0.50	0.28	FALSE
12	BLA	Vezt	gene expression	ENSRNOG00000006514	0.32	0.25	enet	97	0.30	1.1e-16	-6.8	-7.9	3.2e-15	0.68	0.44	0.56	FALSE
13	BLA	Ndufa12	gene expression	ENSRNOG00000007407	0.09	0.01	enet	13	0.03	1.1e-02	-8.5	-5.8	5.3e-09	-0.28	0.31	0.49	FALSE
14	BLA	Metap2	gene expression	ENSRNOG00000021881	0.08	0.07	top1	1	0.07	1.9e-04	-8.8	8.8	1.0e-18	-0.73	0.08	0.20	FALSE
15	BLA	Mir331	gene expression	ENSRNOG00000035543	0.06	0.04	blup	2366	0.06	5.1e-04	-7.3	9.1	8.9e-20	-0.76	0.39	0.60	FALSE
16	BLA	Fgd6	gene expression	ENSRNOG00000054515	0.11	0.13	top1	1	0.13	2.7e-07	-7.9	-7.9	2.5e-15	0.78	0.92	0.01	FALSE
17	BLA	Cdk17	isoform ratio	ENSRNOT00000109496	0.35	0.19	lasso	16	0.20	5.7e-11	2.0	5.1	3.5e-07	0.20	1.00	0.00	FALSE
18	BLA	Tmcc3	isoform ratio	ENSRNOT00000102476	0.10	0.02	blup	2424	0.04	3.2e-03	-7.8	-7.1	1.1e-12	0.64	0.48	0.40	TRUE
19	BLA	AABR07056633.1	isoform ratio	ENSRNOT00000114083	0.18	0.06	top1	1	0.06	6.5e-04	-5.4	-5.4	6.4e-08	0.41	0.14	0.04	FALSE
20	BLA	Lta4h	intron excision ratio	chr7:27997602:27999743	0.07	0.01	blup	2332	0.02	2.6e-02	-5.7	-6.8	7.7e-12	0.53	0.70	0.16	FALSE
21	BLA	Vezt	intron excision ratio	chr7:28557619:28560958	0.07	0.01	blup	2571	0.01	6.6e-02	1.4	7.3	2.9e-13	-0.71	0.46	0.27	FALSE
22	BLA	Tmcc3	intron excision ratio	chr7:29100427:29159418	0.12	0.10	lasso	10	0.11	1.0e-06	-2.7	5.4	6.8e-08	-0.66	0.76	0.22	FALSE
23	BLA	Tmcc3	intron excision ratio	chr7:29133627:29159418	0.07	0.02	blup	2424	0.04	4.3e-03	-7.6	-8.0	8.8e-16	0.71	0.40	0.43	FALSE
24	BLA	Vezt	mRNA stability	ENSRNOG00000006514	0.40	0.42	top1	1	0.42	4.0e-24	-8.6	8.6	1.1e-17	-0.78	0.35	0.65	FALSE
25	BLA	Plxnc1	mRNA stability	ENSRNOG00000007970	0.11	0.11	top1	1	0.11	3.0e-06	-7.8	7.8	4.3e-15	-0.79	0.36	0.03	FALSE
26	Brain	AABR07056633.1	alternative TSS	ENSRNOT00000094647	0.06	0.02	top1	1	0.02	3.3e-03	-5.3	5.3	1.3e-07	-0.36	0.14	0.03	FALSE
27	Brain	AABR07056633.1	alternative TSS	ENSRNOT00000094647	0.06	0.02	top1	1	0.02	4.8e-03	-5.3	5.3	1.3e-07	-0.36	0.12	0.03	FALSE
28	Brain	Cdk17	gene expression	ENSRNOG00000004148	0.12	0.06	enet	78	0.07	1.8e-07	-5.2	5.1	3.4e-07	-0.23	1.00	0.00	FALSE
29	Brain	Lta4h	gene expression	ENSRNOG00000004494	0.05	0.04	top1	1	0.04	9.1e-05	-8.3	8.3	8.1e-17	-0.61	0.11	0.04	FALSE
30	Brain	Vezt	gene expression	ENSRNOG00000006514	0.24	0.22	blup	2571	0.23	1.2e-20	-9.1	-8.4	5.4e-17	0.70	0.12	0.88	FALSE
31	Brain	Ndufa12	gene expression	ENSRNOG00000007407	0.49	0.32	blup	2574	0.34	6.1e-32	-7.3	-7.5	7.4e-14	0.69	1.00	0.00	FALSE
32	Brain	Plxnc1	gene expression	ENSRNOG00000007970	0.05	0.02	blup	3131	0.04	6.3e-05	-2.8	-5.6	2.2e-08	0.71	0.83	0.15	FALSE
33	Brain	Socs2	gene expression	ENSRNOG00000008965	0.22	0.09	enet	118	0.11	5.0e-10	-7.8	6.4	1.5e-10	-0.42	0.99	0.01	FALSE
34	Brain	Metap2	gene expression	ENSRNOG00000021881	0.04	0.01	blup	2312	0.01	1.4e-02	-8.3	7.6	2.9e-14	-0.49	0.32	0.42	FALSE
35	Brain	Ccdc38	gene expression	ENSRNOG00000021892	0.10	0.06	blup	2464	0.07	1.9e-07	2.3	6.2	6.0e-10	-0.36	0.99	0.00	TRUE
36	Brain	Fgd6	gene expression	ENSRNOG00000054515	0.16	0.23	top1	1	0.23	8.6e-21	-8.2	-8.2	3.1e-16	0.74	0.94	0.06	FALSE
37	Brain	Tmcc3	isoform ratio	ENSRNOT00000102476	0.03	0.01	blup	2424	0.01	3.4e-02	-3.1	-6.0	2.2e-09	0.70	0.83	0.05	FALSE
38	Brain	AABR07056633.1	isoform ratio	ENSRNOT00000094647	0.03	0.00	blup	2953	0.01	7.7e-02	1.7	5.7	9.4e-09	-0.38	0.52	0.09	FALSE
39	Brain	Lta4h	intron excision ratio	chr7:27997602:27999743	0.04	0.02	top1	1	0.02	4.8e-03	-6.9	-6.9	4.0e-12	0.54	0.10	0.03	FALSE
40	Brain	Tmcc3	intron excision ratio	chr7:29133627:29159418	0.05	0.01	blup	2424	0.02	7.7e-03	-3.5	-6.0	1.8e-09	0.66	0.90	0.06	FALSE
41	Brain	Lta4h	mRNA stability	ENSRNOG00000004494	0.05	0.02	blup	2332	0.03	9.8e-04	-8.3	7.9	3.0e-15	-0.63	0.46	0.48	FALSE
42	Brain	Vezt	mRNA stability	ENSRNOG00000006514	0.20	0.20	lasso	28	0.20	1.6e-18	-8.1	8.2	2.6e-16	-0.70	0.33	0.67	FALSE
43	Eye	Lta4h	gene expression	ENSRNOG00000004494	0.41	0.04	lasso	24	0.07	3.0e-02	-8.1	8.1	5.3e-16	-0.63	0.26	0.41	FALSE
44	Eye	Fgd6	gene expression	ENSRNOG00000054515	0.52	0.13	blup	2560	0.15	2.3e-03	-7.3	-8.2	3.0e-16	0.78	0.43	0.17	FALSE
45	Eye	Elk3	isoform ratio	ENSRNOT00000005911	0.36	0.01	blup	2579	0.10	1.2e-02	-8.2	-8.3	1.3e-16	0.58	0.26	0.45	FALSE
46	IL	Vezt	gene expression	ENSRNOG00000006514	0.29	0.20	lasso	4	0.26	7.2e-07	-7.3	-7.5	4.4e-14	0.67	0.41	0.58	FALSE
47	IL	Tmcc3	gene expression	ENSRNOG00000007713	0.46	0.16	top1	1	0.16	1.2e-04	5.6	5.6	2.6e-08	0.50	0.13	0.05	TRUE
48	IL	Vezt	mRNA stability	ENSRNOG00000006514	0.23	0.06	blup	2568	0.10	2.4e-03	-7.4	8.4	3.2e-17	-0.76	0.52	0.36	FALSE
49	LHb	Nr2c1	alternative polyA	ENSRNOT00000009578	0.20	0.19	top1	1	0.19	2.6e-05	-6.1	6.1	8.0e-10	-0.63	0.14	0.05	FALSE
50	LHb	Nr2c1	alternative polyA	ENSRNOT00000089228	0.32	0.21	top1	1	0.21	8.9e-06	-6.1	-6.1	8.0e-10	0.62	0.15	0.05	FALSE
51	LHb	Ntn4	gene expression	ENSRNOG00000005573	0.21	0.04	blup	2473	0.06	1.6e-02	-8.5	-8.2	2.0e-16	0.62	0.35	0.44	FALSE
52	LHb	Plxnc1	gene expression	ENSRNOG00000007970	0.41	0.09	blup	3118	0.22	7.2e-06	-3.5	-6.8	1.3e-11	0.74	0.67	0.30	FALSE
53	LHb	Cdk17	isoform ratio	ENSRNOT00000109496	0.18	0.05	blup	2984	0.11	1.4e-03	-4.9	6.7	2.3e-11	-0.45	0.50	0.26	FALSE
54	LHb	Vezt	mRNA stability	ENSRNOG00000006514	0.40	0.20	enet	84	0.21	1.1e-05	-8.2	8.8	1.3e-18	-0.70	0.33	0.67	FALSE
55	Liver	Amdhd1	gene expression	ENSRNOG00000005266	0.37	0.31	lasso	40	0.34	1.7e-39	-6.1	-7.5	8.3e-14	0.55	1.00	0.00	FALSE
56	Liver	Ntn4	gene expression	ENSRNOG00000005573	0.10	0.05	blup	2475	0.06	4.3e-07	-8.0	-9.2	4.5e-20	0.64	0.44	0.56	FALSE
57	Liver	Vezt	gene expression	ENSRNOG00000006514	0.14	0.12	enet	322	0.14	1.7e-15	-6.5	-5.4	8.2e-08	0.48	1.00	0.00	FALSE
58	Liver	Nr2c1	gene expression	ENSRNOG00000006983	0.04	0.03	enet	37	0.03	2.0e-04	-2.8	-5.5	4.7e-08	0.66	0.90	0.08	FALSE
59	Liver	Ndufa12	gene expression	ENSRNOG00000007407	0.42	0.43	enet	320	0.46	1.8e-56	-7.3	-7.2	7.0e-13	0.71	1.00	0.00	FALSE
60	Liver	Ccdc38	gene expression	ENSRNOG00000021892	0.32	0.35	top1	1	0.35	1.8e-40	-6.1	6.1	1.3e-09	-0.54	1.00	0.00	FALSE
61	Liver	Lta4h	mRNA stability	ENSRNOG00000004494	0.11	0.11	top1	1	0.11	6.2e-12	-8.3	8.3	1.3e-16	-0.59	0.84	0.16	FALSE
62	Liver	Amdhd1	mRNA stability	ENSRNOG00000005266	0.24	0.22	top1	1	0.22	6.1e-24	-6.1	-6.1	1.3e-09	0.55	1.00	0.00	FALSE
63	Liver	Snrpf	mRNA stability	ENSRNOG00000005556	0.03	0.02	top1	1	0.02	1.4e-03	-6.4	-6.4	2.1e-10	0.56	0.08	0.03	FALSE
64	Liver	Tmcc3	mRNA stability	ENSRNOG00000007713	0.17	0.05	lasso	13	0.05	1.3e-06	5.3	-5.9	3.2e-09	0.38	0.98	0.02	FALSE
65	NAcc	AABR07056633.1	alternative TSS	ENSRNOT00000094647	0.04	0.04	top1	1	0.04	8.1e-04	-5.2	5.2	1.6e-07	-0.39	0.15	0.03	FALSE
66	NAcc	AABR07056633.1	alternative TSS	ENSRNOT00000104436	0.04	0.03	blup	2952	0.03	1.5e-03	-5.1	-6.1	1.1e-09	0.37	0.93	0.04	FALSE
67	NAcc	AABR07056633.1	alternative TSS	ENSRNOT00000094647	0.05	0.04	top1	1	0.04	6.8e-04	-5.2	5.2	1.6e-07	-0.39	0.18	0.03	FALSE
68	NAcc	AABR07056633.1	alternative TSS	ENSRNOT00000104436	0.05	0.03	blup	2952	0.04	1.1e-03	-5.1	-5.9	3.4e-09	0.35	0.95	0.02	FALSE
69	NAcc	Elk3	gene expression	ENSRNOG00000004367	0.04	0.00	blup	2578	0.02	1.6e-02	2.1	6.8	1.1e-11	-0.39	0.54	0.24	FALSE
70	NAcc	Lta4h	gene expression	ENSRNOG00000004494	0.04	0.05	top1	1	0.05	8.4e-05	-8.8	8.8	1.6e-18	-0.58	0.07	0.48	FALSE
71	NAcc	Vezt	gene expression	ENSRNOG00000006514	0.10	0.09	blup	2569	0.14	1.4e-10	-7.2	-7.7	1.6e-14	0.72	0.93	0.07	FALSE
72	NAcc	Plxnc1	gene expression	ENSRNOG00000007970	0.12	0.13	lasso	6	0.13	1.0e-09	-8.1	-8.2	2.7e-16	0.76	0.88	0.12	FALSE
73	NAcc	Ccdc38	gene expression	ENSRNOG00000021892	0.16	0.07	blup	2462	0.12	5.8e-09	2.4	5.7	9.5e-09	-0.38	0.82	0.18	FALSE
74	NAcc	Fgd6	gene expression	ENSRNOG00000054515	0.20	0.04	enet	12	0.06	1.6e-05	-7.0	-6.8	1.4e-11	-0.30	0.54	0.46	FALSE
75	NAcc	Tmcc3	isoform ratio	ENSRNOT00000102476	0.05	0.02	blup	2420	0.04	8.4e-04	-3.1	-5.7	1.1e-08	0.71	0.54	0.21	FALSE
76	NAcc	Vezt	intron excision ratio	chr7:28535225:28538306	0.06	0.01	blup	2569	0.02	1.7e-02	-7.7	5.6	2.6e-08	-0.34	0.45	0.08	FALSE
77	NAcc	Vezt	intron excision ratio	chr7:28538513:28538938	0.05	0.01	blup	2569	0.02	1.9e-02	-7.7	-6.7	1.6e-11	0.46	0.49	0.24	TRUE
78	NAcc	Tmcc3	intron excision ratio	chr7:29133627:29159418	0.05	0.03	blup	2420	0.05	1.4e-04	-8.1	-7.3	2.1e-13	0.78	0.65	0.30	FALSE
79	NAcc	Lta4h	mRNA stability	ENSRNOG00000004494	0.06	0.05	lasso	7	0.06	3.2e-05	-8.7	8.3	1.4e-16	-0.63	0.41	0.58	FALSE
80	NAcc	Vezt	mRNA stability	ENSRNOG00000006514	0.14	0.08	lasso	10	0.11	1.5e-08	-8.3	8.3	1.0e-16	-0.70	0.60	0.40	FALSE
81	OFC	Vezt	gene expression	ENSRNOG00000006514	0.38	0.25	enet	117	0.28	3.0e-07	-8.3	-8.6	5.5e-18	0.71	0.35	0.65	FALSE
82	OFC	Ndufa12	gene expression	ENSRNOG00000007407	0.19	0.16	top1	1	0.16	1.1e-04	-8.9	-8.9	4.7e-19	0.77	0.07	0.55	FALSE
83	OFC	Vezt	mRNA stability	ENSRNOG00000006514	0.24	0.12	blup	2568	0.14	3.2e-04	-8.2	9.1	9.3e-20	-0.76	0.34	0.64	FALSE
84	PL	AABR07056633.1	alternative TSS	ENSRNOT00000094647	0.09	0.06	top1	1	0.06	2.6e-05	-5.5	5.5	4.2e-08	-0.39	0.88	0.00	FALSE
85	PL	AABR07056633.1	alternative TSS	ENSRNOT00000104436	0.09	0.06	top1	1	0.06	2.2e-05	-5.5	-5.5	4.2e-08	0.39	0.90	0.00	FALSE
86	PL	AABR07056633.1	alternative TSS	ENSRNOT00000094647	0.09	0.06	top1	1	0.06	2.9e-05	-5.5	5.5	4.2e-08	-0.40	0.89	0.00	FALSE
87	PL	AABR07056633.1	alternative TSS	ENSRNOT00000104436	0.09	0.06	top1	1	0.06	2.6e-05	-5.5	-5.5	4.2e-08	0.40	0.89	0.00	FALSE
88	PL	Vezt	gene expression	ENSRNOG00000006514	0.35	0.39	lasso	7	0.41	4.8e-33	-7.0	-7.9	4.0e-15	0.64	0.90	0.10	FALSE
89	PL	Ndufa12	gene expression	ENSRNOG00000007407	0.07	0.06	lasso	18	0.07	1.0e-05	-7.6	-8.1	7.1e-16	0.17	0.46	0.54	FALSE
90	PL	Socs2	gene expression	ENSRNOG00000008965	0.05	0.04	top1	1	0.04	9.1e-04	-8.4	8.4	3.1e-17	-0.82	0.11	0.03	FALSE
91	PL	Fgd6	gene expression	ENSRNOG00000054515	0.07	0.09	lasso	7	0.10	5.4e-08	-7.2	-7.2	5.5e-13	0.72	0.75	0.25	FALSE
92	PL	Vezt	mRNA stability	ENSRNOG00000006514	0.27	0.38	top1	1	0.38	1.6e-30	-8.5	8.5	1.9e-17	-0.78	0.49	0.51	FALSE
93	PL	Plxnc1	mRNA stability	ENSRNOG00000007970	0.05	0.05	top1	1	0.05	1.2e-04	-9.1	9.1	5.8e-20	-0.81	0.21	0.03	FALSE
94	PL	Cradd	mRNA stability	ENSRNOG00000008507	0.09	0.08	top1	1	0.07	2.3e-06	-10.3	10.3	1.1e-24	-0.79	0.02	0.97	TRUE

h2: Heritability estimate for the given transcriptomic model. PP3: Posterior probability of two distinct causal variants. PP4: Posterior probability of a single shared causal variant. joint: Whether the RNA phenotype is in the joint model.