chr7:83,305,298-85,354,043

Trait: Body weight

Best TWAS P=3.77e-10 · Best GWAS P=2.35e-07 conditioned to 1.00e+00

Associated models

Tissue Gene RNA modality RNA phenotype h2 # weights Model R2 Model R2 P TWAS Z TWAS P Coloc P Joint
Brain Ext1 mRNA stability Ext1 0.05 1852 0.05 2.5e-05 5.22 1.82e-07 0.53 TRUE
Brain Med30 mRNA stability Med30 0.05 1926 0.04 1.5e-04 6.26 3.77e-10 0.43 TRUE
Liver Med30 intron excision ratio chr7_84012067_84015230 0.07 18 0.03 1.8e-04 6.04 1.52e-09 0.24 TRUE
NAcc Med30 intron excision ratio chr7_84012067_84026109 0.06 1926 0.05 2.5e-06 5.36 8.14e-08 0.51 FALSE
OFC Med30 gene expression Med30 0.23 65 0.09 3.1e-03 5.28 1.30e-07 0.33 TRUE
PL Med30 isoform ratio NM_001130539.2 0.07 1926 0.06 9.9e-07 6.23 4.80e-10 0.49 FALSE
PL Med30 isoform ratio NM_001399687.1 0.07 1926 0.05 1.2e-06 -6.23 4.60e-10 0.49 FALSE
PL Ext1 mRNA stability Ext1 0.44 71 0.45 2.8e-54 5.43 5.65e-08 0.68 FALSE