LOC120101717

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R² and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

#	Tissue	Modality	RNA phenotype	h²	h² SE	h² P	xQTL R²	BLUP R²	ENET R²	LASSO R²	xQTL P	BLUP P	ENET P	LASSO P
1	Liver	gene expression	LOC120101717	0.05	0.03	1.5e-03	0	0.01	0.01	0.01	9.3e-02	1.9e-02	2.6e-02	6.4e-02
2	Adipose	mRNA stability	LOC120101717	0.05	0.04	3.1e-04	0	0.01	0.01	0.01	2.4e-01	9.9e-03	2.3e-02	4.7e-02
3	Adipose	gene expression	LOC120101717	0.8	0.05	0.0e+00	0.33	0.46	0.47	0.47	4.7e-38	2.3e-57	3.7e-58	5.3e-58

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait	Avg chi² ratio	Avg chi²	Max chi²	1	2	3
Bone: apparent density	0.7	1.2	1.9	-0.6	-1.4	1.2
Area under the delay curve	0.1	0.1	0.1	0.3	0.3	-0.2
BMI with tail	7.4	24.0	43.9	-6.6	5.3	-0.5
BMI without tail	6.6	13.5	19.0	-4.3	4.4	-1.8
Body weight	7.9	33.2	66.5	-8.2	5.6	1.5
Weight adjusted by age	0.3	0.3	0.6	-0.4	0.4	0.8
Bone surface	0.3	0.4	0.9	-0.9	-0.2	0.7
Bone volume	0.4	0.7	0.9	-0.9	-0.9	0.7
Breakpoint value in progressive ratio session	0.9	1.0	2.0	-0.8	1.4	-0.7
Number of licking bursts	0.5	0.6	1.2	-0.2	-0.7	1.1
Context. condit. distance diff. score	0.4	0.5	1.0	1.0	-0.6	-0.4
Locomotion velocity, session 1	1.2	1.3	2.6	1.6	-0.9	-0.7
Locomotion distance, session 1	2.9	3.7	7.2	2.7	-2.0	0.1
Locomotion velocity, session 2	1.6	1.9	4.0	2.0	-1.2	-0.3
Locomotion distance, session 2	3.6	5.1	9.1	3.0	-2.0	-1.5
Locomotion velocity, session 3	3.3	3.8	5.7	2.4	-2.4	-0.2
Locomotion distance, session 3	1.4	1.5	2.3	1.5	-1.5	0.1
Stereotopy head waving bouts, day 3	0.4	0.4	1.2	-1.1	-0.1	0.3
Stereotopy head waving duration, day 3	0.2	0.3	0.4	-0.6	0.3	-0.6
Locomotion velocity, session 7	1.7	1.9	3.3	1.4	-1.8	-0.5
Locomotion distance, session 7	1.8	2.3	3.5	1.2	-1.9	-1.4
Stereotopy head waving bouts, day 7	0.7	0.7	1.6	-0.3	0.7	-1.3
Stereotopy head waving duration, day 7	0.1	0.1	0.2	-0.4	-0.0	-0.0
Locomotion velocity, session 8	1.2	1.4	2.8	1.7	-0.7	-0.9
Locomotion distance, session 8	4.6	6.7	11.7	3.4	-2.4	-1.7
Degree of sensitization distance	0.7	0.7	1.8	-0.6	0.1	-1.3
Degree of sensitization stereotypy	0.4	0.5	0.7	-0.2	0.9	-0.8
Conditioned locomotion	0.6	0.7	1.6	-0.6	-1.3	-0.3
Cocaine response after cond. corrected	1.8	2.0	3.4	1.4	-1.8	-0.8
Cocaine response after cond. not corrected	2.1	2.3	5.5	1.1	-2.4	-0.3
Cocaine response before conditioning	0.4	0.5	0.6	-0.7	-0.5	0.8
Saline control response	0.4	0.5	0.8	-0.9	0.4	-0.7
Bone: connectivity density	1.1	1.8	3.2	-0.3	-1.4	1.8
Bone: cortical apparent density	0.1	0.1	0.3	0.2	-0.2	0.6
Bone: cortical area	1.0	1.5	2.5	-1.6	-0.4	1.3
Bone: cortical porosity	0.8	0.9	2.3	-1.5	0.3	0.5
Bone: cortical porosity	1.0	1.0	2.9	-1.7	0.3	0.3
Bone: cortical thickness	2.3	3.7	6.3	-2.0	-1.0	2.5
Bone: cortical thickness	2.5	2.8	6.8	0.1	-1.3	2.6
Bone: cortical tissue density	0.1	0.1	0.2	0.3	-0.2	0.5
Condit. Reinf. active minus inactive responses	0.2	0.2	0.6	-0.8	-0.1	0.1
Condit. Reinf. active-inactive response ratio	0.1	0.1	0.3	-0.6	-0.2	-0.0
Condit. Reinf. active responses	0.0	0.0	0.0	0.1	0.2	-0.2
Condit. Reinf. inactive responses	0.5	0.6	0.8	0.7	0.6	-0.9
Incentive salience index mean	0.0	0.0	0.1	0.1	-0.0	0.2
Condit. Reinf. lever presses	0.3	0.5	0.7	0.8	0.8	0.1
Condit. Reinf. active minus inactive responses	1.5	1.9	5.1	-0.7	0.2	-2.3
Condit. Reinf. active-inactive response ratio	1.0	1.1	2.4	-0.6	0.7	-1.6
Condit. Reinf. active responses	1.3	1.8	5.0	-0.3	0.7	-2.2
Condit. Reinf. inactive responses	0.1	0.2	0.4	-0.2	0.6	-0.2
Condit. Reinf. lever presses	2.6	3.5	5.1	-1.0	2.3	-2.1
Condit. Reinf. lever reinforcers received	1.7	2.4	6.1	-0.5	1.0	-2.5
Conditioned reinforcement - actives	0.3	0.3	0.6	0.7	-0.8	0.1
Conditioned reinforcement - inactives	0.7	0.8	1.1	0.9	-1.1	0.5
Conditioned locomotion	1.3	1.5	2.4	1.4	-1.6	0.4
Patch foraging indifference point 0 sec	0.2	0.2	0.7	0.8	-0.3	-0.1
Patch foraging indifference point AUC	2.1	2.4	4.8	2.2	-0.7	1.4
Delay disc. indifference point, 0s delay	0.4	0.4	0.9	-0.5	0.9	0.1
Delay disc. indifference point, 16s delay	0.3	0.3	0.7	0.8	-0.4	0.3
Delay disc. indifference point, 2s delay	0.7	0.8	1.4	-0.5	1.2	-0.9
Delay disc. indifference point, 24s delay	1.1	1.1	1.9	1.2	-1.4	0.3
Delay disc. indifference point, 4s delay	0.1	0.1	0.4	-0.1	0.7	-0.1
Delay disc. indifference point, 8s delay	0.4	0.4	0.7	0.9	-0.2	-0.6
Indifference point function ln k	0.5	0.8	1.6	-1.3	0.2	-0.8
Indifference point function log k	0.5	0.8	1.6	-1.3	0.2	-0.8
Patch foraging total patch changes 0 sec	0.4	0.6	1.6	1.3	-0.4	-0.2
Patch foraging total patch changes 12 sec	0.2	0.2	0.3	0.6	0.5	0.0
Patch foraging total patch changes 18 sec	1.9	2.5	6.1	2.5	-1.0	-0.6
Patch foraging total patch changes 24 sec	0.8	1.0	2.9	1.7	-0.4	-0.3
Patch foraging total patch changes 6 sec	0.4	0.6	1.7	1.3	0.0	0.2
Patch foraging time to switch 0 sec	1.7	2.6	5.4	-2.3	1.3	-0.8
Patch foraging water rate 0 sec	2.3	3.7	9.4	3.1	-1.3	0.3
Patch foraging water rate 12 sec	2.3	3.6	5.7	2.4	-2.1	-0.8
Patch foraging water rate 18 sec	4.5	6.0	10.5	2.7	-3.2	-0.5
Patch foraging water rate 24 sec	3.4	4.7	7.5	2.7	-2.5	-0.7
Patch foraging water rate 6 sec	2.0	2.9	6.2	1.5	-2.5	0.6
Seeking ratio, delayed vs. immediate footshock	0.5	0.5	1.4	-1.2	0.4	0.0
Distance traveled before self-admin	1.0	1.0	3.0	0.1	1.7	-0.2
Distance traveled after self-admin	0.7	0.7	1.3	1.1	-0.6	0.7
Extensor digitorum longus weight	0.3	1.1	2.3	-0.9	1.5	0.2
Bone: elastic displacement	0.4	0.5	1.2	-0.6	0.0	1.1
Bone: elastic work	2.1	2.7	4.8	-2.2	1.6	0.8
Bone: endosteal estimation	1.5	3.3	4.3	-1.7	2.1	-1.6
Bone: endosteal perimeter	0.6	1.2	2.6	-0.6	0.7	-1.6
Epididymis fat weight	6.6	15.3	29.0	-5.4	4.0	1.0
Delta time in closed arm before/after self-admin	0.5	0.4	1.3	1.1	-0.2	0.0
Delta time in open arm before/after self-admin	0.7	0.7	2.1	-1.4	0.2	0.1
Diff in mean of infusions in LGA sessions	0.6	0.7	1.1	0.6	0.8	-1.1
Delay discount exponential model param	0.1	0.1	0.2	-0.4	-0.1	-0.0
Extinction: sum of active levers before priming	0.3	0.3	0.5	-0.4	0.7	-0.4
Active lever presses in extinction session 6	0.7	0.7	1.9	-1.4	0.4	0.3
Bone: final force	0.4	0.7	1.6	-1.3	0.1	0.7
Bone: final moment	0.5	0.8	1.7	-1.3	0.1	0.9
Food consumed during 24 hour testing period	1.0	1.2	2.5	-1.6	-0.5	0.9
Glucose	1.3	2.0	2.8	-1.7	1.5	1.0
Heart weight	1.8	2.5	4.9	-2.2	1.3	-1.0
Delay discount hyperbolic model param	0.1	0.1	0.1	-0.3	-0.3	0.2
Intermittent access intake day 1-15 change	1.0	0.9	1.8	-0.6	1.3	-0.9
Intermittent access intake escalation	0.8	0.8	1.5	-0.5	1.2	-0.8
Intermittent access intake escalation 2	2.8	2.7	4.0	-1.7	2.0	-1.2
Intermitt. access day 1 inactive lever presses	0.8	0.9	1.5	-0.9	1.2	0.7
Intermitt. access day 15 inactive lever presses	1.1	1.2	2.9	-1.7	0.9	0.0
Intermitt. access escalation Index	0.9	0.8	1.5	-1.2	0.0	0.9
Intermittent access day 1 total infusions	0.3	0.4	0.7	-0.6	-0.8	0.4
Intermittent access day 15 total infusions	0.2	0.2	0.7	-0.8	-0.0	0.0
Intermittent access terminal intake (last 3 days)	0.5	0.5	1.4	-1.2	0.3	0.0
Intermittent access total infusions	0.4	0.4	1.0	-1.0	-0.3	0.3
Intermittent access day 1 locomotion	0.2	0.2	0.6	-0.2	-0.8	0.3
Intermittent access day 15 total locomotion	0.8	0.8	1.1	-0.8	-0.9	1.0
Intermittent access total locomotion	0.6	0.7	1.6	0.3	-1.3	0.5
Intermittent access standard deviation	0.4	0.4	0.9	0.1	1.0	-0.6
Left kidney weight	1.1	3.2	7.3	-2.7	1.5	-0.3
Right kidney weight	0.9	2.6	6.9	-2.6	1.0	-0.0
Cocaine induced anxiety	0.9	1.0	1.8	1.4	-0.1	-1.1
Post-drug Anxiety	0.9	1.0	1.7	0.4	1.3	-1.1
Baseline Anxiety	2.3	2.5	4.4	-2.1	1.6	0.7
Tail length	0.3	1.0	1.9	-1.4	0.3	1.1
Length with tail	1.7	6.2	11.1	-3.3	1.3	2.4
Length without tail	2.3	5.1	8.0	-2.8	1.0	2.5
Times rat made contact with spout	0.9	1.1	2.5	-0.9	1.6	-0.1
Lifetime Intake	0.1	0.2	0.3	-0.4	-0.6	0.2
Liver weight, left	0.6	1.0	2.1	-0.9	-0.1	1.5
Liver weight, right	1.1	1.8	3.4	-1.4	0.0	1.9
Locomotor activity	1.0	1.6	3.0	-0.0	1.7	-1.4
Locomotor testing distance	0.2	0.4	0.8	0.9	0.4	-0.5
Locomotor testing rearing	0.2	0.3	0.5	0.3	0.6	0.7
Locomotion in novel chamber	0.4	0.5	1.4	0.1	-1.2	0.0
Locomotion in novel chamber post-restriction	1.7	2.1	4.1	0.8	-1.2	2.0
Fecal boli incidents, locomotor time 1	1.0	1.0	1.9	1.4	-0.6	-1.0
Change in fecal boli incidents, locomotor task	1.0	1.0	2.2	-0.7	-0.4	1.5
Time >=10cm from walls, locomotor time 1	0.1	0.1	0.2	-0.2	-0.3	-0.5
Bouts of movement, locomotor time 1	0.4	0.5	0.8	0.7	-0.9	-0.3
Total resting periods, locomotor time 1	0.6	0.7	0.9	0.9	-1.0	-0.4
Rest time, locomotor task time 1	0.2	0.2	0.4	0.5	-0.3	-0.6
Distance moved, locomotor task time 1	0.6	0.6	0.8	0.6	-0.9	0.9
Vertical activity count, locomotor time 1	0.5	0.6	1.1	-1.0	0.4	0.7
Time >=10cm from walls, locomotor time 2	2.8	2.9	5.9	-2.4	1.6	0.6
Bouts of movement, locomotor time 2	1.3	1.4	3.2	0.5	1.0	-1.8
Total resting periods, locomotor time 2	1.7	1.8	3.7	0.4	1.2	-1.9
Rest time, locomotor task time 2	0.6	0.6	1.1	0.8	0.4	-1.0
Distance moved, locomotor task time 2	1.1	1.3	2.5	0.0	-1.1	1.6
Vertical activity count, locomotor time 2	0.2	0.2	0.4	-0.6	-0.3	0.2
Light reinforcement 1	0.2	0.4	0.8	0.5	-0.5	0.9
Light reinforcement 2	0.4	0.5	1.4	0.3	-0.1	1.2
Bone: marrow area	1.5	3.2	4.1	-1.7	2.0	-1.6
Bone: maximum diameter	0.2	0.3	0.8	-0.9	0.2	0.1
Bone: maximum force	0.4	0.7	1.9	-1.4	0.1	0.3
Bone: maximum moment	0.5	0.9	2.3	-1.5	0.1	0.6
Mean time between licks in bursts	1.7	2.4	3.7	-0.6	-1.9	1.8
Mean num. licks in bursts	0.7	0.8	1.6	-0.5	1.3	-0.7
Cd content in liver	0.8	0.9	2.2	-1.5	-0.2	0.6
Co content in liver	2.4	2.8	6.0	-0.0	-1.6	2.4
Cu content in liver	0.1	0.1	0.2	0.3	-0.4	0.3
Fe content in liver	0.9	1.1	2.9	-1.7	0.6	-0.4
K content in liver	1.3	1.2	3.3	1.8	0.3	0.6
Mg content in liver	0.2	0.2	0.3	0.6	0.5	0.3
Mn content in liver	1.8	2.0	3.4	1.8	-1.6	-0.0
Na content in liver	0.6	0.7	1.2	0.2	0.9	1.1
Rb content in liver	0.3	0.3	0.6	-0.3	0.8	0.6
Se content in liver	2.2	2.7	6.4	-1.2	0.6	2.5
Sr content in liver	0.7	0.7	1.0	0.9	-1.0	-0.3
Zn content in liver	0.8	0.9	1.4	-0.9	-0.6	1.2
Bone: minimum diameter	0.4	0.7	2.0	-1.4	0.3	-0.4
Time in familiar zone, hab. session 1	1.3	1.2	3.0	-0.8	0.2	1.7
Time in novel zone, hab. session 1	1.6	1.5	4.0	0.3	0.7	-2.0
Total zone transitions, hab. session 1	0.8	1.2	1.5	0.9	-1.1	1.2
Total locomotion distance, hab. session 1	0.8	1.1	2.1	1.4	-1.0	-0.4
Locomotion velocity, hab. session 1	1.3	1.8	2.9	1.7	-1.6	0.2
Time in familiar zone, hab. session 2	0.0	0.0	0.0	0.1	0.0	0.0
Time in novel zone, hab. session 2	0.3	0.3	0.4	-0.6	0.7	-0.4
Total zone transitions, hab. session 2	0.2	0.2	0.5	0.3	-0.2	-0.7
Total locomotion distance, hab. session 2	1.1	1.5	2.3	1.4	-0.4	-1.5
Locomotion velocity, hab. session 2	1.3	1.7	3.2	1.8	-0.9	-1.0
Novel to familiar place preference ratio	0.3	0.3	0.8	0.0	-0.2	-0.9
Novelty place preference	0.1	0.1	0.3	-0.2	-0.3	-0.5
Time in novel zone, NPP test	0.1	0.1	0.2	-0.5	0.1	-0.3
Total zone transitions, NPP test	0.5	0.8	1.9	1.4	-0.6	-0.2
Total locomotion distance, NPP test	2.3	3.2	5.8	2.4	-1.0	-1.6
Locomotion velocity, NPP test	2.7	3.8	7.1	2.7	-1.6	-1.3
Intraocular pressure	0.8	1.0	2.7	0.6	-1.6	-0.4
Delta distance traveled before/after self-admin	1.4	1.5	2.8	1.0	-1.7	0.9
Delta ambulatory time before/after self-admin	1.5	1.6	3.3	1.1	-1.8	0.6
Parametrial fat weight	10.8	21.1	33.8	-5.8	5.4	-0.6
Pavlov. Cond. lever latency	1.0	1.3	1.9	-1.4	0.3	-1.3
Pavlov. Cond. magazine entry latency	0.6	0.8	1.7	-0.6	1.3	0.6
Pavlov. Cond. change in total contacts	0.4	0.4	1.0	1.0	-0.0	0.5
Pavlov. Cond. index score	0.4	0.5	1.2	0.3	0.5	1.1
Pavlov. Cond. latency score	0.6	0.7	1.5	0.8	-0.0	1.2
Pavlov. Cond. lever contacts	0.4	0.5	1.1	1.0	0.3	0.4
Pavlov. Cond. magazine entry number	0.7	0.9	1.8	0.8	-1.3	-0.5
Pavlov. Cond. intertrial magazine entries	1.8	2.2	2.9	1.2	-1.5	-1.7
Pavlov. Cond. lever-magazine prob. diff.	0.3	0.4	0.6	0.2	0.7	0.8
Pavlov. Cond. response bias	0.4	0.5	1.2	-0.3	1.1	0.3
Pavlov. Cond. lever latency	2.9	4.0	5.1	2.0	-2.3	1.6
Pavlov. Cond. magazine entry latency	0.8	1.0	1.7	-1.3	1.1	-0.2
Pavlov. Cond. change in total contacts	3.6	4.9	6.8	-2.2	2.6	-1.8
Pavlov. Cond. index score	2.7	3.5	4.8	-2.2	2.2	-1.0
Pavlov. Cond. latency score	1.9	2.3	3.2	-1.8	1.8	-0.8
Pavlov. Cond. lever contacts	2.8	3.8	5.5	-1.9	2.4	-1.5
Pavlov. Cond. magazine entry number	1.4	1.7	2.8	1.7	-1.5	0.4
Pavlov. Cond. intertrial magazine entries	0.5	0.7	0.8	0.9	-0.7	-0.9
Pavlov. Cond. lever-magazine prob. diff.	3.1	4.0	5.9	-2.3	2.4	-0.8
Pavlov. Cond. response bias	2.6	3.5	4.4	-1.9	2.1	-1.5
Time in closed arm before self-admin	0.4	0.4	0.8	0.2	-0.9	0.7
Time in closed arm after self-admin	2.0	2.0	3.2	1.5	-1.8	0.8
Time in open arm before self-admin	0.6	0.6	1.4	-0.6	1.2	0.3
Time in open arm after self-admin	1.4	1.6	2.4	-1.6	1.5	0.0
Bone: periosteal estimation	0.8	1.7	3.7	-1.9	1.0	-0.6
Bone: periosteal perimeter	0.3	0.5	0.9	-0.9	-0.2	-0.7
Bone: post-yield work	1.0	1.4	2.9	-1.7	0.4	-1.1
Progressive ratio test 1 active lever presses	0.1	0.1	0.1	0.4	-0.2	-0.3
Progressive ratio test 1 breakpoint	0.1	0.1	0.2	0.4	-0.1	-0.4
Progressive ratio test 1 inactive lever presses	0.2	0.2	0.3	0.5	0.4	-0.4
Progressive ratio test 2 active lever presses	0.0	0.0	0.1	-0.1	0.1	-0.3
Progressive ratio test 2 breakpoint	0.1	0.1	0.1	-0.1	0.3	-0.3
Progressive ratio test 2 inactive lever presses	0.5	0.6	0.9	-1.0	0.8	-0.4
Incentive Sensitization - Responses	0.1	0.1	0.2	-0.4	0.1	0.4
Incentive Sensitization - Breakpoint	0.1	0.1	0.1	-0.3	0.1	0.4
Sum of active levers in priming session hrs 5-6	0.4	0.4	0.8	0.9	-0.6	0.1
Progressive ratio	0.7	0.9	1.4	1.0	-1.2	0.3
Food seeking constrained by brief footshock	2.8	3.5	6.7	2.6	-1.8	0.9
Seeking ratio, punishment vs. effort	0.1	0.2	0.4	0.2	0.7	-0.1
Retroperitoneal fat weight	11.0	36.1	63.6	-8.0	6.7	0.3
Reaction time number correct	0.4	0.6	1.0	1.0	-0.5	-0.7
Reaction time mean minus median	1.5	2.0	3.5	-1.5	1.9	-0.3
Reaction time mean minus median AUC	1.3	1.7	2.4	-1.3	1.5	0.9
Reaction time num false alarms	1.7	2.3	6.4	0.6	-2.5	0.4
Reaction time num false alarms AUC	1.3	1.7	4.3	0.8	-2.1	0.4
Reaction time trials correct on left	0.4	0.6	1.0	1.0	-0.5	-0.7
Reaction time trials on left	0.4	0.6	1.1	1.0	-0.5	-0.7
Reaction time mean	2.7	3.7	7.0	-1.9	2.7	-0.8
Reaction time mean AUC	2.4	3.2	5.8	-1.9	2.4	-0.6
Median of all reaction times	2.3	3.1	6.1	-1.6	2.5	-0.8
Reaction time omissions	0.8	1.1	1.8	-0.3	1.2	1.3
Reaction time false alarm rate	0.9	1.3	3.2	0.4	-1.8	0.8
Reaction time premature initiation rate	0.3	0.4	0.6	0.0	-0.8	0.6
Reaction time premature initiations	0.3	0.5	0.9	0.7	-1.0	0.2
Std. dev. reaction times	1.9	2.7	5.0	-1.6	2.2	-0.7
Reaction time trials completed	0.4	0.6	1.1	1.0	-0.5	-0.7
Reaction time trials AUC	0.4	0.6	0.9	0.9	-0.4	-1.0
Run reversals in cocaine runway, females	0.8	0.8	1.7	-1.3	0.8	0.2
Run reversals in cocaine runway, males	0.9	0.8	1.7	-0.3	0.9	-1.3
Latency to leave start box in cocaine runway	0.8	0.9	2.4	-1.6	-0.2	-0.5
Latency to leave start box in cocaine runway, F	1.7	1.9	5.6	-2.4	0.1	-0.4
Latency to leave start box in cocaine runway, M	0.2	0.2	0.3	0.6	-0.3	-0.3
Std. dev. time between licks in bursts	1.6	1.9	3.4	0.6	-1.8	1.4
Total sessions with >9 infusions	0.1	0.1	0.2	0.2	-0.5	-0.1
Short access day 1 total inactive lever presses	0.5	0.5	0.8	-0.3	-0.8	0.9
Short access day 10 total inactive lever presses	1.2	1.4	2.5	-1.3	1.6	0.0
Short access day 1 total infusions	0.5	0.5	0.8	0.8	-0.9	0.2
Short access day 10 total infusions	0.3	0.3	0.6	0.8	-0.5	-0.3
Short access total infusions	0.1	0.1	0.2	0.2	-0.4	-0.0
Short access day 1 locomotion	0.4	0.5	1.3	1.1	-0.3	-0.2
Short access day 10 total locomotion	0.8	0.9	2.3	1.5	-0.1	-0.7
Short access total locomotion	0.9	0.9	2.2	1.5	-0.2	-0.7
One hour access (0.3 mA shock)	0.4	0.5	1.0	1.0	-0.5	-0.5
Compulsive drug intake	0.8	0.8	1.3	1.2	-0.9	0.7
One hour access (shock baseline)	0.2	0.2	0.5	-0.7	0.2	-0.4
Social response proportion	4.2	4.6	7.2	-2.5	2.7	-0.6
Social responses	0.2	0.2	0.4	0.0	0.5	-0.7
Social time	0.9	1.1	1.8	-1.3	1.3	-0.1
Soleus weight	0.1	0.4	0.7	-0.8	0.5	0.6
Bone: stiffness	0.2	0.3	0.5	-0.7	-0.7	0.1
Tibialis anterior weight	1.4	4.6	7.3	-2.5	2.7	0.3
Time to tail flick, vehicle, before self-admin	3.9	4.0	8.2	-2.9	1.8	0.8
Time to tail flick, vehicle, after self-admin	0.0	0.0	0.1	0.1	0.3	-0.1
Time to tail flick, test, before self-admin	0.1	0.1	0.2	-0.4	-0.0	-0.1
Time to tail flick, test, after self-admin	0.1	0.1	0.2	-0.5	-0.5	-0.0
Delta time to tail flick, vehicle, before/after SA	2.1	2.1	4.3	2.1	-1.3	-0.5
Delta time to tail flick, test, before/after SA	0.1	0.1	0.1	0.2	0.0	-0.3
Tibia length	2.6	7.5	19.4	-4.4	1.0	1.4
Ambulatory time before self-admin	0.8	0.8	2.3	-0.1	1.5	0.2
Ambulatory time after self-admin	1.2	1.3	2.4	1.5	-1.1	0.6
Bone: tissue strength	0.5	0.5	0.9	-0.9	0.5	-0.7
Total heroin consumption	0.0	0.0	0.1	-0.0	0.2	0.2
Bone: trabecular number	1.1	1.7	2.7	-0.4	-1.5	1.7
Bone: trabecular spacing	1.1	1.4	2.1	-0.3	1.4	-1.5
Bone: trabecular thickness	3.3	3.9	10.3	-1.1	-0.4	3.2
Bone: trabecular tissue density	0.2	0.3	0.7	-0.9	0.5	0.1
Water consumed over 24 hours	0.1	0.1	0.3	-0.5	-0.1	0.2
Number of responses in last shaping day	0.5	0.5	0.8	0.6	-0.9	-0.5