Hub : Genes

LOC120101717

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R² and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

#	Tissue	Modality	RNA phenotype	h2	h2 SE	h2 P	xQTL R2	BLUP R2	ENET R2	LASSO R2	xQTL P	BLUP P	ENET P	LASSO P
1	Liver	gene expression	LOC120101717	0.13	0.07	3.2e-08	0.06	0.06	0.06	0.06	3.2e-07	5.9e-07	6.0e-07	3.9e-07
2	Adipose	mRNA stability	LOC120101717	0.07	0.05	1.0e-04	0.03	0.03	0.02	0.03	3.0e-04	4.0e-04	3.7e-03	7.6e-04
3	Adipose	gene expression	LOC120101717	0.83	0.04	0.0e+00	0.39	0.48	0.48	0.48	1.1e-45	2.7e-60	4.0e-60	1.6e-60

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3
Bone: apparent density	1.4	2.6	4.2	-0.5	2.1	-1.8
Area under the delay curve	0.2	0.3	0.7	-0.8	-0.1	0.5
BMI with tail	6.0	20.9	55.4	7.4	-2.6	0.7
BMI without tail	3.1	16.7	40.0	6.3	-2.8	1.6
Body weight	6.3	27.6	77.1	8.8	-2.0	-1.2
Weight adjusted by age	0.1	0.2	0.4	0.3	-0.2	-0.6
Bone surface	0.3	0.6	1.0	-0.1	1.0	-0.8
Bone volume	0.6	1.1	2.4	-0.2	1.5	-1.0
Breakpoint value in progressive ratio session	0.2	0.4	0.8	0.4	-0.9	0.4
Number of licking bursts	0.3	1.0	1.7	-0.2	1.3	-1.2
Context. condit. distance diff. score	0.2	0.3	0.4	-0.6	0.6	0.3
Locomotion velocity, session 1	1.3	1.4	3.4	-1.8	0.7	0.6
Locomotion distance, session 1	2.8	3.6	9.6	-3.1	1.1	-0.4
Locomotion velocity, session 2	1.1	1.3	4.0	-2.0	0.1	0.2
Locomotion distance, session 2	3.0	4.2	10.3	-3.2	1.0	1.2
Locomotion velocity, session 3	2.3	2.7	5.5	-2.4	1.6	0.1
Locomotion distance, session 3	0.9	1.0	2.1	-1.4	0.9	-0.0
Stereotopy head waving bouts, day 3	0.5	0.5	1.3	0.3	0.5	-1.1
Stereotopy head waving duration, day 3	0.1	0.1	0.4	0.6	-0.2	-0.0
Locomotion velocity, session 7	1.0	1.1	1.7	-1.3	1.1	0.5
Locomotion distance, session 7	1.1	1.5	1.6	-1.1	1.3	1.2
Stereotopy head waving bouts, day 7	0.4	0.4	0.6	0.8	-0.7	0.3
Stereotopy head waving duration, day 7	0.1	0.1	0.2	-0.0	-0.0	-0.4
Locomotion velocity, session 8	0.7	0.8	2.0	-1.4	0.4	0.6
Locomotion distance, session 8	2.9	4.2	9.0	-3.0	1.4	1.3
Degree of sensitization distance	0.4	0.5	0.9	0.7	0.1	0.9
Degree of sensitization stereotypy	0.7	0.8	1.4	0.6	-1.2	0.7
Conditioned locomotion	1.0	1.2	2.8	0.2	1.7	-0.8
Cocaine response after cond. corrected	0.6	1.0	1.7	-1.3	1.0	0.5
Cocaine response after cond. not corrected	1.1	1.6	2.5	-1.6	1.4	-0.2
Cocaine response before conditioning	0.4	0.4	0.9	-0.3	0.6	-0.9
Saline control response	0.1	0.1	0.3	0.2	-0.4	0.5
Bone: connectivity density	2.3	3.7	5.6	-1.3	2.0	-2.4
Bone: cortical apparent density	0.1	0.1	0.2	-0.4	0.1	-0.4
Bone: cortical area	0.9	1.5	2.1	0.7	1.4	-1.4
Bone: cortical porosity	0.8	0.8	1.8	0.4	0.8	-1.3
Bone: cortical porosity	0.6	0.7	0.9	0.7	0.8	-0.9
Bone: cortical thickness	2.4	3.9	7.7	0.4	2.0	-2.8
Bone: cortical thickness	3.6	4.4	8.2	-1.3	1.8	-2.9
Bone: cortical tissue density	0.1	0.1	0.1	-0.4	-0.0	-0.3
Condit. Reinf. active minus inactive responses	0.2	0.2	0.5	0.7	-0.2	-0.5
Condit. Reinf. active-inactive response ratio	0.1	0.1	0.3	0.6	-0.0	-0.1
Condit. Reinf. active responses	0.3	0.4	1.1	0.3	-1.0	0.1
Condit. Reinf. inactive responses	0.7	0.9	2.0	-0.1	-1.4	0.9
Incentive salience index mean	0.2	0.2	0.6	0.0	-0.7	-0.3
Condit. Reinf. lever presses	0.8	1.2	3.4	-0.1	-1.9	0.5
Condit. Reinf. active minus inactive responses	0.9	1.3	2.8	1.1	-0.2	1.7
Condit. Reinf. active-inactive response ratio	0.7	1.1	2.0	0.9	-0.6	1.4
Condit. Reinf. active responses	1.4	2.0	3.7	1.1	-1.0	1.9
Condit. Reinf. inactive responses	0.3	0.4	0.8	0.7	-0.9	0.2
Condit. Reinf. lever presses	2.7	4.0	5.0	1.6	-2.1	2.2
Condit. Reinf. lever reinforcers received	1.8	2.5	4.5	1.2	-1.2	2.1
Conditioned reinforcement - actives	0.3	1.1	2.1	-1.4	1.1	-0.1
Conditioned reinforcement - inactives	0.2	0.4	0.6	-0.6	0.6	-0.8
Conditioned locomotion	1.0	1.5	3.9	-2.0	0.8	-0.1
Patch foraging indifference point 0 sec	0.1	0.3	0.6	-0.5	-0.7	-0.0
Patch foraging indifference point AUC	0.7	1.7	4.8	-2.2	-0.1	-0.6
Delay disc. indifference point, 0s delay	0.1	0.1	0.2	0.0	0.1	0.4
Delay disc. indifference point, 16s delay	0.4	0.6	1.6	-1.3	-0.3	-0.3
Delay disc. indifference point, 2s delay	0.7	0.7	1.7	0.6	-0.5	1.3
Delay disc. indifference point, 24s delay	0.7	1.1	2.8	-1.7	0.7	-0.3
Delay disc. indifference point, 4s delay	0.2	0.2	0.6	-0.0	-0.0	0.8
Delay disc. indifference point, 8s delay	0.3	0.5	0.8	-0.9	0.4	0.7
Indifference point function ln k	0.2	0.5	1.2	1.1	0.4	-0.3
Indifference point function log k	0.2	0.5	1.2	1.1	0.4	-0.3
Patch foraging total patch changes 0 sec	0.2	0.6	0.9	-1.0	-0.9	0.2
Patch foraging total patch changes 12 sec	0.6	0.8	1.9	-0.4	-1.4	0.6
Patch foraging total patch changes 18 sec	0.6	1.5	2.8	-1.7	-0.6	1.1
Patch foraging total patch changes 24 sec	0.3	1.1	1.7	-1.3	-1.0	0.8
Patch foraging total patch changes 6 sec	0.6	1.0	2.6	-0.6	-1.6	0.3
Patch foraging time to switch 0 sec	0.5	2.0	5.9	2.4	0.1	0.2
Patch foraging water rate 0 sec	0.7	2.6	7.1	-2.7	-0.7	0.4
Patch foraging water rate 12 sec	0.4	1.7	4.2	-2.1	0.6	0.6
Patch foraging water rate 18 sec	1.7	3.8	8.8	-3.0	1.6	-0.2
Patch foraging water rate 24 sec	1.1	1.6	4.5	-2.1	0.5	0.3
Patch foraging water rate 6 sec	1.3	1.9	3.2	-1.8	1.4	-0.7
Seeking ratio, delayed vs. immediate footshock	0.1	0.2	0.4	0.6	0.5	0.0
Distance traveled before self-admin	0.8	1.8	2.2	1.2	-1.5	1.3
Distance traveled after self-admin	0.2	0.3	0.6	-0.8	0.4	-0.1
Extensor digitorum longus weight	0.1	0.4	0.9	1.0	-0.5	0.0
Bone: elastic displacement	0.1	0.2	0.4	0.3	-0.2	-0.7
Bone: elastic work	1.2	1.6	3.3	1.8	-1.0	-0.7
Bone: endosteal estimation	1.0	2.5	4.5	2.1	-0.7	1.6
Bone: endosteal perimeter	0.5	1.2	2.7	0.9	-0.3	1.6
Epididymis fat weight	3.2	16.1	44.6	6.7	-1.9	-0.5
Delta time in closed arm before/after self-admin	0.1	0.1	0.1	-0.2	-0.3	-0.1
Delta time in open arm before/after self-admin	0.6	0.8	1.8	1.3	-0.4	-0.6
Diff in mean of infusions in LGA sessions	0.8	1.5	2.1	0.6	-1.4	1.5
Delay discount exponential model param	0.3	0.4	1.0	1.0	-0.1	-0.4
Extinction: sum of active levers before priming	0.5	0.8	1.5	-0.7	-1.2	0.7
Active lever presses in extinction session 6	0.9	0.9	1.1	1.0	1.0	-0.8
Bone: final force	0.3	0.4	0.6	0.8	0.6	-0.5
Bone: final moment	0.3	0.6	0.6	0.7	0.8	-0.8
Food consumed during 24 hour testing period	1.1	2.2	3.7	0.2	1.7	-1.9
Glucose	0.7	1.2	2.8	1.7	-0.7	-0.3
Heart weight	0.7	1.2	3.2	1.8	-0.1	0.6
Delay discount hyperbolic model param	0.1	0.2	0.4	0.6	-0.1	-0.4
Intermittent access intake day 1-15 change	0.1	0.3	0.5	0.3	-0.6	0.7
Intermittent access intake escalation	0.1	0.3	0.7	0.3	-0.3	0.9
Intermittent access intake escalation 2	0.5	0.8	1.3	1.1	-0.7	0.8
Intermitt. access day 1 inactive lever presses	0.1	1.7	3.8	1.9	-1.1	0.2
Intermitt. access day 15 inactive lever presses	0.2	1.0	2.5	1.6	0.3	-0.7
Intermitt. access escalation Index	0.1	0.3	0.4	0.7	0.2	-0.6
Intermittent access day 1 total infusions	0.1	0.4	1.0	0.5	1.0	-0.1
Intermittent access day 15 total infusions	0.3	0.7	1.3	0.9	1.1	0.0
Intermittent access terminal intake (last 3 days)	0.3	0.6	1.5	1.2	0.5	-0.2
Intermittent access total infusions	0.5	0.6	0.8	0.9	0.8	-0.5
Intermittent access day 1 locomotion	0.4	0.7	1.7	-0.3	1.3	0.6
Intermittent access day 15 total locomotion	0.2	0.7	1.0	-0.4	1.0	-1.0
Intermittent access total locomotion	0.6	0.7	1.2	-1.1	1.0	0.2
Intermittent access standard deviation	0.0	0.0	0.0	-0.2	0.1	0.1
Left kidney weight	0.5	3.7	10.9	3.3	-0.2	-0.5
Right kidney weight	0.2	1.3	3.9	2.0	0.1	-0.4
Cocaine induced anxiety	0.2	0.6	1.5	-0.0	0.5	1.2
Post-drug Anxiety	1.2	1.4	2.5	1.6	-0.5	1.2
Baseline Anxiety	1.6	2.7	4.1	2.0	-2.0	-0.4
Tail length	0.3	1.3	2.6	1.1	0.4	-1.6
Length with tail	1.1	5.1	11.0	3.3	-0.0	-2.1
Length without tail	0.9	4.7	9.3	3.1	0.7	-2.1
Times rat made contact with spout	0.6	0.7	1.5	0.7	-1.2	0.1
Lifetime Intake	0.3	0.4	0.6	0.5	0.8	-0.5
Liver weight, left	1.4	2.5	4.4	2.1	-1.3	1.1
Liver weight, right	1.1	1.9	5.1	2.3	-0.6	-0.6
Locomotor activity	1.4	2.1	3.1	0.7	-1.6	1.8
Locomotor testing distance	0.2	0.4	1.0	-0.4	-0.4	1.0
Locomotor testing rearing	0.0	0.1	0.2	-0.4	-0.2	0.1
Locomotion in novel chamber	0.4	0.6	1.1	-1.0	0.6	-0.4
Locomotion in novel chamber post-restriction	0.9	2.7	5.7	-1.3	0.8	-2.4
Fecal boli incidents, locomotor time 1	0.3	0.8	1.2	-1.1	0.3	1.1
Change in fecal boli incidents, locomotor task	1.3	1.4	3.6	0.3	0.8	-1.9
Time >=10cm from walls, locomotor time 1	0.0	0.0	0.1	0.3	0.2	-0.2
Bouts of movement, locomotor time 1	0.3	0.3	0.6	-0.5	0.8	0.4
Total resting periods, locomotor time 1	0.3	0.4	0.6	-0.8	0.6	0.3
Rest time, locomotor task time 1	0.1	0.2	0.5	-0.1	-0.7	0.1
Distance moved, locomotor task time 1	0.3	0.7	0.9	-0.9	0.9	-0.7
Vertical activity count, locomotor time 1	0.1	0.4	0.8	0.5	0.5	-0.9
Time >=10cm from walls, locomotor time 2	0.7	2.0	4.6	2.1	-0.4	-1.2
Bouts of movement, locomotor time 2	0.6	2.1	4.2	0.3	-1.4	2.0
Total resting periods, locomotor time 2	0.6	2.6	4.8	0.7	-1.6	2.2
Rest time, locomotor task time 2	0.6	1.1	1.7	-0.0	-1.2	1.3
Distance moved, locomotor task time 2	1.5	2.0	2.5	-1.1	1.4	-1.6
Vertical activity count, locomotor time 2	0.2	0.4	0.8	-0.3	0.9	-0.7
Light reinforcement 1	0.2	0.8	1.2	-1.1	0.7	-0.9
Light reinforcement 2	0.3	0.8	1.1	-0.9	0.7	-1.1
Bone: marrow area	1.0	2.3	4.2	2.1	-0.6	1.6
Bone: maximum diameter	0.1	0.2	0.4	0.6	0.5	-0.1
Bone: maximum force	0.3	0.5	0.9	1.0	0.7	-0.4
Bone: maximum moment	0.3	0.7	0.8	0.9	0.8	-0.7
Mean time between licks in bursts	0.7	4.3	7.6	-0.4	2.3	-2.7
Mean num. licks in bursts	0.4	1.0	2.1	0.5	-1.4	0.8
Cd content in liver	0.3	0.4	0.5	0.7	0.5	-0.6
Co content in liver	2.3	2.7	4.1	-0.6	2.0	-2.0
Cu content in liver	0.4	0.4	0.9	-0.6	-0.2	-1.0
Fe content in liver	1.2	1.5	4.0	2.0	-0.6	-0.2
K content in liver	1.1	1.1	1.6	-1.2	-1.3	0.1
Mg content in liver	0.2	0.2	0.4	0.3	-0.6	-0.2
Mn content in liver	0.7	0.8	1.5	-1.2	0.2	1.0
Na content in liver	0.9	1.0	1.2	-0.8	-1.1	-1.1
Rb content in liver	1.0	1.2	1.7	1.0	-1.3	-1.0
Se content in liver	1.6	1.9	4.0	1.3	-0.2	-2.0
Sr content in liver	0.9	0.8	2.1	-1.4	0.4	-0.2
Zn content in liver	0.9	1.1	2.1	0.2	1.1	-1.5
Bone: minimum diameter	0.4	0.8	1.7	1.3	0.8	0.2
Time in familiar zone, hab. session 1	0.7	0.7	2.1	0.0	-0.3	-1.5
Time in novel zone, hab. session 1	1.4	1.5	3.6	0.7	-0.7	1.9
Total zone transitions, hab. session 1	1.5	2.2	2.6	-1.6	1.2	-1.6
Total locomotion distance, hab. session 1	0.6	0.9	2.4	-1.6	0.5	-0.3
Locomotion velocity, hab. session 1	1.3	1.9	4.1	-2.0	0.9	-0.9
Time in familiar zone, hab. session 2	0.2	0.2	0.6	-0.8	0.4	0.0
Time in novel zone, hab. session 2	0.7	0.8	1.5	1.2	-0.7	0.6
Total zone transitions, hab. session 2	0.2	0.2	0.3	-0.5	0.5	0.4
Total locomotion distance, hab. session 2	0.9	1.2	2.0	-1.4	-0.1	1.2
Locomotion velocity, hab. session 2	1.0	1.4	3.5	-1.9	0.3	0.8
Novel to familiar place preference ratio	0.3	0.3	0.6	0.6	-0.0	0.8
Novelty place preference	0.1	0.2	0.4	0.6	0.1	0.4
Time in novel zone, NPP test	0.3	0.4	0.7	0.8	-0.2	0.6
Total zone transitions, NPP test	0.6	0.9	2.2	-1.5	0.5	0.5
Total locomotion distance, NPP test	1.8	2.5	5.0	-2.2	0.2	1.6
Locomotion velocity, NPP test	2.0	2.9	6.6	-2.6	0.7	1.3
Intraocular pressure	0.4	0.7	1.6	-0.7	1.3	-0.2
Delta distance traveled before/after self-admin	3.0	3.3	4.9	-2.2	1.9	-1.2
Delta ambulatory time before/after self-admin	1.8	3.0	4.2	-2.1	2.0	-0.9
Parametrial fat weight	10.9	25.6	61.8	7.9	-3.9	0.2
Pavlov. Cond. lever latency	0.4	0.5	1.4	1.2	0.4	0.1
Pavlov. Cond. magazine entry latency	0.3	0.4	0.7	0.9	-0.8	-0.2
Pavlov. Cond. change in total contacts	0.3	0.3	0.7	-0.3	-0.9	-0.0
Pavlov. Cond. index score	0.1	0.1	0.2	-0.1	-0.5	-0.4
Pavlov. Cond. latency score	0.2	0.2	0.4	-0.6	-0.2	-0.5
Pavlov. Cond. lever contacts	0.2	0.3	0.6	-0.5	-0.8	0.2
Pavlov. Cond. magazine entry number	0.5	0.7	1.0	-0.9	1.0	-0.3
Pavlov. Cond. intertrial magazine entries	0.4	0.5	1.0	-1.0	0.1	0.7
Pavlov. Cond. lever-magazine prob. diff.	0.2	0.2	0.6	0.0	-0.8	-0.1
Pavlov. Cond. response bias	0.3	0.3	0.6	0.7	-0.8	0.0
Pavlov. Cond. lever latency	2.2	3.1	5.3	-2.3	1.7	-1.1
Pavlov. Cond. magazine entry latency	0.6	0.8	1.3	1.2	-0.8	0.6
Pavlov. Cond. change in total contacts	1.7	4.2	6.6	2.6	-2.0	1.5
Pavlov. Cond. index score	1.8	2.8	5.0	2.2	-1.6	0.9
Pavlov. Cond. latency score	1.3	2.0	3.7	1.9	-1.4	0.7
Pavlov. Cond. lever contacts	2.2	3.2	5.5	2.3	-1.8	1.0
Pavlov. Cond. magazine entry number	0.9	1.2	2.4	-1.6	1.0	-0.6
Pavlov. Cond. intertrial magazine entries	0.2	0.3	0.5	-0.7	0.3	0.7
Pavlov. Cond. lever-magazine prob. diff.	2.0	3.1	5.8	2.4	-1.7	0.8
Pavlov. Cond. response bias	2.4	3.3	5.8	2.4	-1.6	1.2
Time in closed arm before self-admin	0.3	0.6	1.3	0.0	1.1	-0.7
Time in closed arm after self-admin	0.9	1.0	1.2	-1.0	1.1	-1.0
Time in open arm before self-admin	0.2	0.2	0.4	0.3	0.7	0.3
Time in open arm after self-admin	0.7	0.7	1.5	1.2	-0.8	-0.3
Bone: periosteal estimation	0.5	1.1	3.0	1.7	0.5	0.4
Bone: periosteal perimeter	0.2	0.3	0.5	0.6	0.5	0.7
Bone: post-yield work	0.4	0.8	1.5	0.9	1.2	0.1
Progressive ratio test 1 active lever presses	0.4	0.6	1.9	0.1	-1.4	0.2
Progressive ratio test 1 breakpoint	0.4	0.6	1.8	0.1	-1.3	0.2
Progressive ratio test 1 inactive lever presses	0.5	1.3	2.1	0.3	-1.3	1.4
Progressive ratio test 2 active lever presses	0.4	0.6	1.8	0.2	-1.3	0.3
Progressive ratio test 2 breakpoint	0.4	0.5	1.4	0.2	-1.2	0.2
Progressive ratio test 2 inactive lever presses	0.2	0.5	1.2	0.7	-1.1	0.0
Incentive Sensitization - Responses	0.1	0.2	0.4	-0.1	-0.6	-0.4
Incentive Sensitization - Breakpoint	0.1	0.2	0.4	-0.2	-0.7	-0.4
Sum of active levers in priming session hrs 5-6	0.1	0.1	0.2	-0.5	-0.0	-0.0
Progressive ratio	0.5	1.6	2.0	-1.3	1.0	-1.4
Food seeking constrained by brief footshock	2.6	3.2	7.8	-2.8	1.3	-0.1
Seeking ratio, punishment vs. effort	0.2	0.4	1.2	-0.0	-0.2	1.1
Retroperitoneal fat weight	12.4	55.5	137.8	11.7	-5.3	0.4
Reaction time number correct	0.1	0.4	0.8	-0.5	-0.2	0.9
Reaction time mean minus median	0.3	2.1	3.7	1.6	-1.9	-0.1
Reaction time mean minus median AUC	0.3	1.8	3.1	1.1	-1.8	-1.0
Reaction time num false alarms	1.8	3.0	5.7	-1.5	2.4	-1.1
Reaction time num false alarms AUC	0.9	2.1	3.1	-1.5	1.7	-0.9
Reaction time trials correct on left	0.1	0.4	0.8	-0.5	-0.2	0.9
Reaction time trials on left	0.1	0.4	0.8	-0.5	-0.3	0.9
Reaction time mean	1.3	2.9	4.2	2.0	-2.1	0.7
Reaction time mean AUC	1.0	2.4	3.5	1.9	-1.9	0.5
Median of all reaction times	1.5	2.3	3.1	1.8	-1.8	0.8
Reaction time omissions	0.8	1.3	3.3	0.7	-1.8	-0.4
Reaction time false alarm rate	1.4	2.0	2.9	-1.2	1.7	-1.2
Reaction time premature initiation rate	0.5	0.8	1.2	-0.3	1.1	-1.0
Reaction time premature initiations	0.2	0.5	0.6	-0.7	0.7	-0.6
Std. dev. reaction times	0.8	2.8	4.6	1.9	-2.2	0.4
Reaction time trials completed	0.1	0.4	0.8	-0.5	-0.3	0.9
Reaction time trials AUC	0.1	0.5	1.2	-0.4	-0.3	1.1
Run reversals in cocaine runway, females	0.1	0.1	0.3	0.5	-0.1	-0.2
Run reversals in cocaine runway, males	1.4	1.5	2.5	1.1	-0.9	1.6
Latency to leave start box in cocaine runway	0.5	0.7	1.0	0.8	1.0	-0.7
Latency to leave start box in cocaine runway, F	1.3	1.6	2.3	1.5	1.3	-0.8
Latency to leave start box in cocaine runway, M	0.2	0.2	0.6	-0.8	0.2	-0.1
Std. dev. time between licks in bursts	1.1	2.1	3.2	-1.1	1.3	-1.8
Total sessions with >9 infusions	0.1	0.1	0.2	-0.5	-0.1	-0.2
Short access day 1 total inactive lever presses	0.3	0.6	1.2	0.5	1.1	-0.4
Short access day 10 total inactive lever presses	0.2	1.6	4.5	2.1	0.1	0.5
Short access day 1 total infusions	0.7	1.4	2.4	-1.6	1.2	-0.7
Short access day 10 total infusions	0.2	0.3	0.8	-0.0	-0.1	0.9
Short access total infusions	0.1	0.2	0.4	-0.1	0.6	-0.4
Short access day 1 locomotion	0.2	0.4	0.8	-0.9	-0.6	0.2
Short access day 10 total locomotion	0.4	1.5	2.4	-1.6	-0.4	1.4
Short access total locomotion	0.8	1.2	1.8	-1.3	-0.1	1.3
One hour access (0.3 mA shock)	0.3	0.3	0.9	-0.9	-0.1	0.2
Compulsive drug intake	0.6	0.8	2.5	-1.6	0.2	-0.1
One hour access (shock baseline)	0.1	0.3	0.4	0.4	0.6	-0.6
Social response proportion	2.7	3.4	6.2	2.5	-1.6	1.1
Social responses	0.5	0.7	1.2	-0.1	-1.1	0.9
Social time	0.3	0.5	0.8	0.8	-0.9	0.3
Soleus weight	0.1	0.2	0.3	0.5	0.2	-0.5
Bone: stiffness	0.3	0.5	1.2	0.4	1.1	-0.2
Tibialis anterior weight	0.6	2.2	5.4	2.3	-1.1	-0.0
Time to tail flick, vehicle, before self-admin	1.6	2.0	5.3	2.3	0.2	-0.8
Time to tail flick, vehicle, after self-admin	0.2	0.3	0.9	1.0	-0.2	0.1
Time to tail flick, test, before self-admin	0.2	0.3	0.4	-0.3	0.6	-0.6
Time to tail flick, test, after self-admin	0.3	0.4	1.1	-0.2	1.0	-0.1
Delta time to tail flick, vehicle, before/after SA	0.4	0.4	0.8	-0.9	-0.4	0.5
Delta time to tail flick, test, before/after SA	0.2	0.3	0.7	0.2	0.1	0.9
Tibia length	2.1	5.9	9.5	3.1	1.9	-2.2
Ambulatory time before self-admin	0.5	1.5	2.2	1.3	-1.5	0.9
Ambulatory time after self-admin	0.4	0.6	1.2	-1.1	0.7	-0.0
Bone: tissue strength	0.3	0.3	0.4	0.6	-0.4	0.6
Total heroin consumption	0.3	0.4	1.0	0.3	-1.0	0.1
Bone: trabecular number	1.8	3.3	4.9	-0.6	2.2	-2.1
Bone: trabecular spacing	2.1	3.1	3.7	1.4	-1.9	1.9
Bone: trabecular thickness	3.0	4.1	10.6	-0.5	1.2	-3.3
Bone: trabecular tissue density	0.0	0.1	0.2	0.5	-0.1	-0.1
Water consumed over 24 hours	0.0	0.1	0.1	-0.3	0.3	0.1
Number of responses in last shaping day	0.5	0.7	1.8	-1.4	0.5	-0.2