Rrbp1

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Liver alternative polyA XM_063283804.1 0.03 0.03 2.5e-03 0 0 -0 -0 1.9e-01 2.6e-01 4.2e-01 5.4e-01
2 Brain isoform ratio NM_001427599.1 0.03 0.03 2.2e-03 0.02 0.02 0.01 0.01 4.4e-03 6.7e-03 8.1e-02 1.6e-02
3 Brain gene expression Rrbp1 0.13 0.07 3.1e-15 0.16 0.18 0.18 0.17 1.6e-14 1.9e-16 3.5e-16 4.5e-16
4 NAcc gene expression Rrbp1 0.05 0.03 8.5e-09 0.07 0.06 0.06 0.03 2.2e-10 6.9e-09 3.8e-10 3.1e-05
5 pVTA gene expression Rrbp1 0.28 0.14 4.2e-12 0.17 0.14 0.15 0.17 1.4e-13 2.4e-11 9.0e-12 2.3e-13
6 LHb gene expression Rrbp1 0.23 0.14 3.0e-04 0.08 0.11 0.07 0.07 6.3e-03 1.7e-03 1.1e-02 8.5e-03
7 RMTg gene expression Rrbp1 0.23 0.11 1.4e-05 0.22 0.12 0.17 0.18 2.2e-06 4.2e-04 3.5e-05 2.1e-05
8 Liver alternative polyA NM_001427599.1 0.03 0.02 8.3e-03 -0 -0 0 -0 3.9e-01 7.6e-01 2.8e-01 9.9e-01
9 pVTA alternative TSS XM_063283801.1 0.05 0.04 2.6e-03 0.02 0.03 0.01 0.03 6.2e-03 2.4e-03 5.3e-02 2.0e-03
10 PL gene expression Rrbp1 0.03 0.02 1.8e-03 0.02 0 0.01 0.01 2.3e-03 8.7e-02 1.4e-02 1.1e-02
11 Liver isoform ratio XM_063283804.1 0.04 0.03 5.7e-04 0 0.01 -0 0 7.4e-02 4.8e-02 8.4e-01 1.5e-01
12 Liver isoform ratio NM_001427599.1 0.05 0.04 4.3e-04 0.01 0.03 0.03 0.03 1.9e-02 2.8e-04 5.5e-04 4.3e-04
13 Adipose alternative TSS NM_001427599.1 0.04 0.04 6.6e-03 0.01 0.01 0.02 0.01 9.5e-03 8.1e-03 2.9e-03 1.1e-02
14 Adipose isoform ratio XM_063283801.1 0.04 0.04 7.4e-03 0 0.01 0.01 0.01 1.2e-01 2.1e-02 2.7e-02 3.3e-02
15 Adipose isoform ratio NM_001427599.1 0.04 0.04 8.1e-03 0.01 0.01 0.02 0.01 2.2e-02 1.9e-02 3.5e-03 2.3e-02
16 Liver isoform ratio XM_063283801.1 0.24 0.31 1.3e-04 0.02 0.02 0.03 0.02 1.1e-03 2.2e-03 1.8e-04 3.3e-03
17 Adipose alternative TSS XM_063283801.1 0.05 0.03 3.2e-04 0.01 0.02 0.03 0.01 6.0e-02 3.3e-03 5.3e-04 1.6e-02
18 Adipose alternative TSS XM_063283801.1 0.04 0.03 7.2e-04 0.01 0.01 0.01 0.01 6.5e-02 1.3e-02 8.3e-03 2.7e-02
19 Adipose gene expression Rrbp1 0.57 0.2 2.1e-06 0.05 0.05 0.07 0.04 5.7e-06 2.6e-06 9.6e-09 1.7e-05

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19
Bone: apparent density0.10.20.4-0.50.40.30.40.50.30.40.6-0.30.2-0.60.60.2-0.60.1-0.6-0.4-0.1-0.1
Area under the delay curve1.41.64.1-0.70.70.60.70.60.30.51.5-0.11.2-1.81.91.1-1.81.9-0.1-2.0-1.81.3
BMI with tail8.228.244.36.5-6.5-6.6-6.5-6.4-6.7-6.4-5.06.3-6.04.5-4.3-5.14.2-3.74.32.72.7-3.0
BMI without tail7.723.434.55.8-5.8-5.8-5.8-5.9-5.9-5.8-4.55.7-5.44.0-3.8-4.73.7-3.84.62.73.0-3.1
Body weight11.349.569.98.4-8.4-8.3-8.1-8.2-8.3-8.1-7.37.9-7.66.6-6.5-7.26.3-5.75.44.64.5-3.2
Weight adjusted by age0.20.42.00.6-0.6-0.1-0.4-0.3-0.1-0.6-0.50.20.20.5-0.5-0.70.7-0.5-0.80.60.71.4
Bone surface0.20.40.50.6-0.6-0.7-0.6-0.6-0.7-0.6-0.50.5-0.70.7-0.7-0.70.7-0.60.40.30.5-0.5
Bone volume0.10.20.50.3-0.3-0.4-0.3-0.2-0.3-0.2-0.40.2-0.50.5-0.5-0.70.6-0.7-0.10.50.7-0.3
Breakpoint value in progressive ratio session0.20.30.50.4-0.4-0.5-0.4-0.6-0.5-0.4-0.50.5-0.70.5-0.5-0.50.5-0.60.70.50.5-0.6
Number of licking bursts0.10.21.1-0.20.20.00.0-0.0-0.0-0.10.50.2-0.4-0.70.7-0.1-0.7-0.10.7-0.20.1-1.1
Context. condit. distance diff. score0.10.20.8-0.00.00.1-0.10.10.2-0.10.00.0-0.40.0-0.0-0.5-0.0-0.80.10.90.9-0.9
Locomotion velocity, session 10.50.61.5-0.80.81.10.80.91.10.80.1-1.11.20.0-0.10.30.10.3-0.6-0.1-0.21.1
Locomotion distance, session 13.13.96.2-2.52.52.52.32.32.42.31.7-2.42.4-1.51.41.9-1.41.7-1.2-1.3-1.31.4
Locomotion velocity, session 22.52.95.7-1.61.61.51.41.51.41.41.4-1.32.0-1.41.42.4-1.42.4-0.8-2.2-2.41.3
Locomotion distance, session 22.83.98.3-2.82.82.82.42.42.92.41.5-2.72.5-1.11.01.5-0.90.9-1.4-0.3-0.41.1
Locomotion velocity, session 33.03.55.2-2.32.32.22.22.22.12.22.0-2.22.0-1.71.71.6-1.61.4-1.5-1.1-1.20.9
Locomotion distance, session 31.41.62.2-1.51.51.31.41.31.21.41.5-1.31.3-1.41.31.0-1.31.2-0.7-1.1-1.20.4
Stereotopy head waving bouts, day 30.10.10.30.2-0.2-0.0-0.1-0.0-0.0-0.1-0.4-0.10.10.5-0.5-0.10.5-0.2-0.40.30.20.4
Stereotopy head waving duration, day 30.20.20.50.5-0.5-0.3-0.3-0.2-0.3-0.3-0.70.1-0.30.7-0.7-0.30.7-0.5-0.20.60.5-0.1
Locomotion velocity, session 70.40.51.3-0.60.61.00.80.81.00.8-0.1-1.11.10.1-0.10.70.10.4-1.1-0.1-0.30.5
Locomotion distance, session 70.20.20.80.1-0.10.2-0.1-0.10.4-0.1-0.9-0.30.20.9-0.9-0.10.8-0.5-0.00.70.6-0.4
Stereotopy head waving bouts, day 70.10.10.30.5-0.5-0.5-0.4-0.4-0.6-0.4-0.20.4-0.10.2-0.10.00.20.30.0-0.2-0.40.5
Stereotopy head waving duration, day 70.20.31.3-0.30.30.20.40.50.10.40.5-0.40.5-0.50.50.3-0.40.6-0.6-0.5-0.61.2
Locomotion velocity, session 80.40.51.2-1.01.01.00.80.91.10.80.1-1.11.00.1-0.20.30.2-0.0-0.50.50.20.9
Locomotion distance, session 81.31.94.9-2.02.02.11.61.72.21.61.1-1.91.7-0.70.71.1-0.70.3-0.60.30.20.3
Degree of sensitization distance2.32.45.01.6-1.6-1.2-1.5-1.4-1.0-1.5-2.21.0-1.12.2-2.2-1.42.1-1.70.51.61.7-0.5
Degree of sensitization stereotypy0.20.20.60.6-0.6-0.7-0.6-0.6-0.8-0.6-0.30.7-0.60.2-0.2-0.40.2-0.20.50.1-0.00.0
Conditioned locomotion0.30.31.00.3-0.20.0-0.1-0.10.1-0.1-0.9-0.10.10.9-0.9-0.71.0-0.8-0.30.70.90.4
Cocaine response after cond. corrected0.70.82.4-1.21.31.41.11.21.51.00.4-1.30.9-0.30.20.5-0.2-0.3-0.90.50.5-0.1
Cocaine response after cond. not corrected1.41.63.9-1.71.81.81.61.62.01.50.8-1.81.4-0.60.60.7-0.50.0-1.40.40.40.2
Cocaine response before conditioning0.20.30.5-0.60.50.40.60.50.40.60.7-0.50.7-0.60.60.3-0.50.6-0.5-0.4-0.50.4
Saline control response2.83.78.61.5-1.5-1.0-1.5-1.4-0.7-1.5-2.50.8-1.22.7-2.7-2.02.7-2.70.62.92.8-0.9
Bone: connectivity density0.40.60.9-0.70.70.70.70.80.60.70.9-0.60.7-0.90.80.9-0.90.9-0.6-0.9-0.80.4
Bone: cortical apparent density0.91.22.1-1.11.10.81.01.00.71.11.4-0.70.7-1.41.41.1-1.41.3-0.8-1.4-1.20.2
Bone: cortical area0.10.21.20.3-0.3-0.6-0.6-0.6-0.6-0.50.00.7-0.30.1-0.1-0.00.00.21.1-0.3-0.4-0.0
Bone: cortical porosity0.10.20.70.2-0.2-0.4-0.4-0.5-0.4-0.40.10.7-0.4-0.10.1-0.4-0.20.10.8-0.2-0.2-0.4
Bone: cortical porosity0.40.41.60.6-0.6-0.7-0.8-0.8-0.7-0.8-0.31.0-0.70.3-0.3-0.80.2-0.31.30.20.3-0.6
Bone: cortical thickness0.50.82.3-0.40.4-0.20.00.1-0.20.11.30.50.2-1.21.30.9-1.41.30.7-1.5-1.5-0.2
Bone: cortical thickness1.21.43.6-1.11.00.70.90.90.60.91.3-0.51.3-1.41.30.8-1.31.7-0.3-1.6-1.71.9
Bone: cortical tissue density0.71.01.7-1.01.00.71.01.00.71.01.2-0.70.6-1.31.31.0-1.31.1-0.8-1.2-1.10.1
Condit. Reinf. active minus inactive responses0.10.20.8-0.50.50.20.30.30.20.30.5-0.2-0.2-0.30.3-0.3-0.3-0.40.20.40.5-0.9
Condit. Reinf. active-inactive response ratio0.10.10.5-0.40.40.20.40.40.30.40.5-0.3-0.1-0.40.4-0.4-0.3-0.4-0.30.30.4-0.7
Condit. Reinf. active responses0.10.20.4-0.60.60.40.40.40.40.40.6-0.30.0-0.40.40.1-0.4-0.10.20.10.1-0.6
Condit. Reinf. inactive responses0.10.10.30.1-0.1-0.1-0.3-0.3-0.1-0.3-0.50.10.10.5-0.50.20.50.20.5-0.0-0.20.6
Incentive salience index mean0.91.12.3-1.21.20.80.90.90.70.91.5-0.60.6-1.41.51.0-1.41.0-0.0-1.2-1.0-0.6
Condit. Reinf. lever presses1.41.95.8-1.01.00.50.70.70.40.71.7-0.30.6-1.91.91.9-2.02.00.2-2.4-2.2-0.4
Condit. Reinf. active minus inactive responses1.82.34.61.5-1.4-1.2-1.6-1.5-1.0-1.5-1.91.3-1.51.8-1.7-1.11.6-1.71.11.61.5-2.1
Condit. Reinf. active-inactive response ratio1.51.74.91.1-1.1-1.0-1.3-1.3-0.9-1.3-1.31.2-1.51.2-1.2-1.11.1-1.61.21.41.4-2.2
Condit. Reinf. active responses0.60.93.11.2-1.2-1.0-1.1-1.1-1.0-1.1-1.01.1-1.00.8-0.7-0.30.6-0.50.40.30.2-1.7
Condit. Reinf. inactive responses0.30.42.30.4-0.4-0.4-0.1-0.0-0.5-0.10.40.30.3-0.50.60.7-0.61.3-0.6-1.3-1.50.2
Condit. Reinf. lever presses3.14.35.92.2-2.3-2.2-2.3-2.3-2.1-2.3-2.12.1-2.42.0-1.9-1.91.9-2.01.61.61.6-2.3
Condit. Reinf. lever reinforcers received0.81.13.91.4-1.3-1.2-1.2-1.2-1.0-1.2-1.11.2-1.20.9-0.8-0.40.7-0.70.60.50.4-2.0
Conditioned reinforcement - actives0.71.34.3-1.51.51.20.70.31.41.0-0.4-1.10.71.0-1.1-0.11.0-1.02.11.61.30.7
Conditioned reinforcement - inactives0.91.43.3-1.21.21.30.90.71.50.7-0.4-1.50.71.0-1.2-0.41.2-1.20.21.81.71.5
Conditioned locomotion1.31.73.8-2.02.01.41.50.91.41.71.4-1.20.9-1.21.11.3-1.20.51.7-0.4-0.4-0.6
Patch foraging indifference point 0 sec0.61.13.5-0.10.10.40.10.10.60.2-1.1-0.8-0.01.5-1.6-1.11.7-1.4-0.61.91.60.5
Patch foraging indifference point AUC1.62.33.6-1.71.71.41.71.61.31.51.9-1.11.4-1.91.81.4-1.91.5-0.9-1.5-1.40.3
Delay disc. indifference point, 0s delay0.60.62.00.2-0.2-0.5-0.4-0.6-0.7-0.50.60.9-0.3-0.90.90.6-1.01.01.4-1.3-1.2-0.2
Delay disc. indifference point, 16s delay2.02.23.6-1.51.51.31.41.41.11.31.9-1.01.5-1.91.91.4-1.91.6-0.7-1.6-1.50.9
Delay disc. indifference point, 2s delay0.70.73.70.8-0.7-1.0-0.9-1.0-1.2-0.90.01.3-0.5-0.40.50.0-0.60.61.9-1.0-0.7-0.1
Delay disc. indifference point, 24s delay3.53.96.5-1.71.71.81.91.91.71.82.0-1.62.5-2.12.11.7-1.92.3-2.1-2.1-2.02.6
Delay disc. indifference point, 4s delay0.60.61.70.7-0.7-0.8-0.7-0.8-1.0-0.80.11.1-0.2-0.50.60.1-0.60.81.3-1.1-1.00.4
Delay disc. indifference point, 8s delay1.31.52.7-1.01.01.00.90.90.80.71.5-0.61.5-1.61.61.0-1.61.6-0.6-1.6-1.41.5
Indifference point function ln k0.71.33.51.0-1.0-0.6-0.8-0.7-0.6-0.6-1.50.1-0.21.6-1.6-1.61.8-0.9-0.41.21.01.9
Indifference point function log k0.71.33.51.0-1.0-0.6-0.8-0.7-0.6-0.6-1.50.1-0.21.6-1.6-1.61.8-0.9-0.41.21.01.9
Patch foraging total patch changes 0 sec0.50.82.9-0.50.50.70.30.40.80.4-0.7-1.00.21.2-1.2-0.91.3-1.2-0.51.71.50.5
Patch foraging total patch changes 12 sec0.20.20.40.4-0.4-0.4-0.5-0.5-0.4-0.6-0.60.5-0.10.6-0.60.00.6-0.00.60.0-0.10.3
Patch foraging total patch changes 18 sec0.81.22.6-1.61.61.51.41.41.61.30.9-1.61.2-0.40.30.6-0.30.1-1.20.20.20.5
Patch foraging total patch changes 24 sec0.10.20.8-0.60.60.60.60.60.60.30.3-0.50.1-0.10.10.3-0.2-0.2-0.50.30.3-0.9
Patch foraging total patch changes 6 sec0.20.30.7-0.60.60.60.70.70.70.50.1-0.80.00.1-0.1-0.10.2-0.6-0.80.80.8-0.5
Patch foraging time to switch 0 sec1.02.14.42.0-2.0-1.9-1.9-1.9-1.9-2.0-1.32.1-1.51.0-0.9-0.50.8-0.31.20.2-0.0-1.1
Patch foraging water rate 0 sec1.53.16.0-2.52.42.22.22.22.22.22.0-2.21.7-1.61.51.2-1.40.9-1.1-0.7-0.61.0
Patch foraging water rate 12 sec2.86.08.2-2.92.82.52.62.62.52.92.9-2.52.3-2.62.52.6-2.52.2-2.0-2.0-1.91.1
Patch foraging water rate 18 sec4.57.012.3-3.13.13.43.03.13.33.22.1-3.33.5-1.71.61.9-1.41.8-2.6-1.1-1.03.4
Patch foraging water rate 24 sec1.92.76.1-2.52.42.41.92.02.41.81.4-2.22.0-1.00.91.0-0.80.5-1.0-0.00.01.3
Patch foraging water rate 6 sec3.45.07.9-2.62.62.62.72.72.62.52.2-2.82.5-1.81.71.5-1.61.5-2.7-1.1-1.02.2
Seeking ratio, delayed vs. immediate footshock0.70.81.80.9-0.9-0.8-0.9-0.7-0.7-0.9-1.20.7-0.61.3-1.3-1.21.3-0.80.10.80.7-0.1
Distance traveled before self-admin0.30.41.20.5-0.5-0.7-0.6-0.6-0.8-0.8-0.00.9-0.3-0.00.10.2-0.10.61.1-0.7-0.90.5
Distance traveled after self-admin1.01.23.0-1.01.00.80.80.70.70.71.6-0.40.8-1.71.71.3-1.71.20.3-1.4-1.20.2
Extensor digitorum longus weight0.31.22.31.2-1.2-1.0-0.9-0.9-1.0-0.8-1.40.7-0.61.4-1.4-1.51.5-0.80.10.80.81.1
Bone: elastic displacement0.30.30.70.5-0.5-0.7-0.6-0.6-0.7-0.6-0.30.8-0.30.1-0.10.4-0.00.60.5-0.8-0.9-0.5
Bone: elastic work1.72.25.01.7-1.7-2.1-1.9-1.9-2.1-1.8-1.12.2-1.80.7-0.7-0.90.6-0.41.7-0.1-0.0-1.5
Bone: endosteal estimation3.78.213.03.0-3.0-2.6-2.7-2.7-2.5-2.7-3.62.1-2.63.5-3.4-3.33.5-3.21.52.93.1-0.8
Bone: endosteal perimeter1.32.75.81.4-1.4-1.0-1.3-1.2-0.9-1.3-1.90.7-1.22.3-2.2-1.72.3-2.30.92.32.4-0.5
Epididymis fat weight9.833.446.16.8-6.8-6.6-6.7-6.5-6.6-6.7-6.16.3-6.05.6-5.4-6.45.4-4.93.94.14.0-2.8
Delta time in closed arm before/after self-admin0.20.22.1-0.20.10.30.40.70.40.30.1-0.50.4-0.10.1-0.1-0.00.1-1.50.0-0.00.1
Delta time in open arm before/after self-admin1.51.43.01.2-1.2-1.4-1.1-1.4-1.4-1.1-1.01.2-1.70.9-0.9-1.10.9-1.21.50.90.9-1.4
Diff in mean of infusions in LGA sessions0.60.82.7-0.00.0-0.20.20.0-0.30.30.90.20.1-1.11.11.4-1.21.4-0.0-1.6-1.6-0.3
Delay discount exponential model param1.61.74.10.8-0.8-0.7-0.8-0.7-0.5-0.7-1.60.3-1.41.8-1.9-1.21.8-1.90.32.01.8-1.5
Extinction: sum of active levers before priming0.20.21.2-0.10.10.40.60.60.40.7-0.1-0.70.30.2-0.2-0.30.30.0-1.10.20.10.8
Active lever presses in extinction session 61.61.63.61.1-1.1-1.3-1.4-1.5-1.2-1.3-1.41.3-1.31.5-1.5-1.01.4-1.01.91.00.8-0.6
Bone: final force0.40.61.10.8-0.8-1.1-0.9-0.8-1.0-0.9-0.61.0-0.80.6-0.6-0.90.6-0.50.70.40.4-0.5
Bone: final moment0.30.51.00.7-0.8-1.0-0.9-0.8-1.0-0.9-0.50.9-0.70.6-0.6-0.80.6-0.30.90.20.2-0.3
Food consumed during 24 hour testing period0.20.30.60.8-0.8-0.6-0.7-0.7-0.7-0.7-0.70.6-0.40.6-0.6-0.50.5-0.20.40.10.10.1
Glucose1.82.95.61.7-1.7-1.6-1.6-1.5-1.5-1.7-2.21.2-1.32.3-2.3-2.12.4-1.50.61.71.40.3
Heart weight2.13.29.11.6-1.6-1.7-2.3-2.2-1.7-1.9-1.91.9-1.42.0-2.0-1.41.9-1.43.01.41.2-0.1
Delay discount hyperbolic model param1.01.13.20.4-0.4-0.3-0.4-0.3-0.0-0.3-1.2-0.1-1.01.5-1.5-0.91.5-1.6-0.21.81.6-1.3
Intermittent access intake day 1-15 change0.91.86.70.8-0.8-1.0-1.5-1.6-0.8-1.0-1.51.1-1.21.6-1.6-0.81.4-1.32.61.41.2-1.3
Intermittent access intake escalation0.61.25.20.6-0.6-0.8-1.2-1.3-0.6-0.7-1.30.9-0.91.4-1.4-0.41.2-1.02.31.10.8-0.9
Intermittent access intake escalation 21.31.46.60.5-0.5-0.9-1.2-1.4-0.9-0.8-1.11.0-1.31.3-1.3-0.81.1-1.32.61.21.0-1.1
Intermitt. access day 1 inactive lever presses0.31.311.50.6-0.60.10.20.20.1-0.2-0.9-0.50.81.0-1.1-1.11.3-0.1-2.30.60.43.4
Intermitt. access day 15 inactive lever presses1.32.67.50.7-0.7-0.4-0.7-0.9-0.2-0.5-2.1-0.2-0.72.6-2.7-2.02.7-2.00.52.52.21.1
Intermitt. access escalation Index0.40.51.31.0-1.0-0.8-1.0-0.7-0.8-1.1-0.60.9-0.70.3-0.3-0.80.3-0.5-0.30.30.4-0.7
Intermittent access day 1 total infusions0.10.20.90.4-0.4-0.3-0.3-0.4-0.3-0.4-0.40.30.20.4-0.4-0.10.40.30.5-0.1-0.21.0
Intermittent access day 15 total infusions1.11.65.21.0-1.0-1.1-1.5-1.6-0.9-1.1-1.71.1-0.71.7-1.7-0.71.5-0.72.30.90.5-0.1
Intermittent access terminal intake (last 3 days)1.41.85.61.2-1.2-1.3-1.6-1.8-1.1-1.2-1.71.3-0.91.8-1.8-0.71.6-0.62.40.80.4-0.3
Intermittent access total infusions0.80.93.40.7-0.7-0.7-0.8-1.1-0.6-0.6-1.20.7-0.71.3-1.3-0.71.1-0.81.90.90.7-0.2
Intermittent access day 1 locomotion0.50.71.6-0.60.60.40.60.20.40.50.9-0.20.9-1.01.00.9-1.01.30.6-1.2-1.20.9
Intermittent access day 15 total locomotion0.40.78.0-0.40.4-0.2-0.3-0.7-0.1-0.2-0.10.4-0.70.3-0.3-0.10.1-0.62.80.60.6-1.4
Intermittent access total locomotion0.60.74.8-1.11.10.50.6-0.00.60.60.8-0.20.3-0.70.71.0-0.80.52.2-0.5-0.5-0.7
Intermittent access standard deviation0.10.10.4-0.40.40.30.20.00.40.6-0.1-0.50.10.3-0.30.20.2-0.10.40.30.10.3
Left kidney weight1.36.18.22.8-2.8-2.8-2.7-2.9-2.8-2.5-2.62.6-2.72.5-2.5-2.62.4-2.02.11.71.7-1.4
Right kidney weight0.52.22.91.5-1.5-1.6-1.7-1.6-1.5-1.4-1.51.4-1.61.7-1.7-1.61.7-1.41.21.41.2-0.4
Cocaine induced anxiety0.10.20.8-0.50.50.50.50.40.50.50.2-0.60.60.0-0.00.00.10.1-0.10.10.10.9
Post-drug Anxiety0.91.02.21.5-1.5-1.1-1.0-0.9-1.1-1.1-1.30.9-0.71.1-1.1-1.21.1-0.6-0.50.60.50.5
Baseline Anxiety2.73.26.82.6-2.6-2.3-2.2-1.9-2.3-2.2-2.02.1-2.01.4-1.3-1.71.3-1.0-0.00.60.6-0.8
Tail length0.72.94.11.8-1.8-1.7-1.7-1.9-1.7-1.8-2.01.8-1.71.8-1.7-1.71.7-1.81.71.41.6-0.9
Length with tail3.013.018.74.0-4.0-3.8-3.8-3.9-3.7-3.7-4.33.6-3.54.0-4.0-3.84.0-3.52.73.13.0-0.9
Length without tail2.37.510.43.0-3.1-3.0-3.0-2.9-2.9-2.9-3.02.8-2.83.1-3.0-3.23.0-2.41.52.32.1-0.5
Times rat made contact with spout3.33.85.32.1-2.1-2.0-2.3-2.3-2.0-2.3-2.22.1-2.11.9-1.9-1.41.7-1.62.01.21.3-1.8
Lifetime Intake0.50.63.80.2-0.2-0.4-0.5-0.8-0.3-0.3-0.80.4-0.71.0-1.0-0.60.8-0.81.90.90.8-0.6
Liver weight, left2.94.96.92.6-2.6-2.2-2.3-2.2-2.1-2.3-2.62.0-2.02.4-2.3-2.62.4-2.40.72.12.2-0.6
Liver weight, right3.05.38.73.0-2.9-2.4-2.2-2.3-2.4-2.4-2.82.1-2.22.5-2.4-2.72.5-2.20.21.92.0-0.9
Locomotor activity0.20.30.60.7-0.7-0.5-0.8-0.6-0.6-0.6-0.60.5-0.40.4-0.4-0.70.4-0.40.10.30.40.0
Locomotor testing distance0.10.20.4-0.50.50.50.30.40.50.40.5-0.40.3-0.60.60.3-0.60.2-0.3-0.2-0.2-0.0
Locomotor testing rearing0.10.32.0-0.40.40.30.10.10.30.00.50.0-0.5-0.40.4-0.2-0.5-0.70.30.60.7-1.4
Locomotion in novel chamber0.91.24.2-0.90.91.41.71.61.41.40.6-1.70.9-0.40.4-0.1-0.2-0.3-2.00.50.60.7
Locomotion in novel chamber post-restriction1.22.04.5-1.71.71.82.01.81.82.11.3-1.91.5-1.21.10.4-1.00.2-1.5-0.10.20.5
Fecal boli incidents, locomotor time 10.50.74.3-0.30.30.60.40.50.70.5-0.5-0.80.90.6-0.7-0.80.8-0.6-0.90.90.92.1
Change in fecal boli incidents, locomotor task0.20.20.5-0.30.30.40.60.60.50.20.3-0.50.2-0.30.40.4-0.40.3-0.7-0.3-0.3-0.7
Time >=10cm from walls, locomotor time 10.30.30.5-0.70.70.60.60.60.60.70.5-0.60.6-0.30.30.2-0.20.2-0.6-0.1-0.10.7
Bouts of movement, locomotor time 10.70.84.7-1.21.21.10.80.91.00.70.7-1.01.3-0.30.30.4-0.20.5-0.4-0.1-0.22.2
Total resting periods, locomotor time 11.01.25.6-1.31.31.31.01.21.31.00.6-1.31.5-0.20.20.4-0.10.5-1.0-0.1-0.12.4
Rest time, locomotor task time 10.30.41.0-0.10.10.40.00.30.5-0.0-0.6-0.50.40.8-0.8-0.60.9-0.7-1.01.00.90.9
Distance moved, locomotor task time 12.03.07.2-1.31.30.91.21.00.81.22.0-0.71.3-2.22.22.5-2.32.60.1-2.6-2.70.4
Vertical activity count, locomotor time 10.10.31.70.0-0.1-0.5-0.2-0.5-0.6-0.00.50.6-0.6-0.50.50.3-0.60.31.3-0.5-0.5-0.8
Time >=10cm from walls, locomotor time 21.21.72.51.5-1.4-1.5-1.4-1.4-1.5-1.4-1.41.4-1.21.4-1.4-1.61.4-1.21.11.01.0-0.1
Bouts of movement, locomotor time 20.10.20.80.4-0.4-0.3-0.6-0.5-0.4-0.9-0.10.7-0.1-0.00.10.0-0.10.10.4-0.2-0.2-0.3
Total resting periods, locomotor time 20.10.20.90.5-0.4-0.4-0.7-0.6-0.4-0.9-0.30.8-0.20.2-0.2-0.20.1-0.10.50.10.0-0.2
Rest time, locomotor task time 20.10.20.90.2-0.2-0.0-0.3-0.2-0.0-0.3-0.60.00.30.6-0.6-0.30.7-0.0-0.10.20.10.9
Distance moved, locomotor task time 21.31.62.7-1.11.11.01.21.20.91.21.5-0.91.0-1.61.61.5-1.61.5-0.6-1.5-1.50.1
Vertical activity count, locomotor time 20.30.31.0-0.50.40.10.50.40.10.51.0-0.0-0.1-0.90.90.5-1.00.3-0.1-0.6-0.5-0.9
Light reinforcement 10.20.62.5-0.40.40.3-0.2-0.30.3-0.0-0.5-0.1-0.40.8-0.9-0.70.8-1.21.61.41.4-0.1
Light reinforcement 20.71.14.6-0.10.10.3-0.1-0.30.40.1-1.0-0.3-0.21.2-1.3-1.51.3-1.81.12.02.20.4
Bone: marrow area3.78.112.93.0-3.0-2.6-2.7-2.6-2.5-2.7-3.62.1-2.63.5-3.4-3.33.5-3.21.42.93.1-0.8
Bone: maximum diameter1.42.63.81.4-1.4-1.4-1.7-1.6-1.3-1.7-1.71.3-1.41.9-1.9-1.71.9-1.81.81.71.7-0.6
Bone: maximum force0.20.40.80.5-0.5-0.9-0.7-0.6-0.8-0.6-0.30.8-0.70.5-0.5-0.90.5-0.50.70.50.4-0.5
Bone: maximum moment0.20.30.70.5-0.5-0.8-0.7-0.6-0.8-0.6-0.30.7-0.60.4-0.4-0.70.4-0.30.80.20.2-0.3
Mean time between licks in bursts0.20.51.5-0.70.70.80.90.90.80.81.2-0.80.4-0.90.90.0-0.80.1-1.10.20.10.0
Mean num. licks in bursts1.01.63.81.5-1.5-1.2-1.4-1.3-1.2-1.3-1.91.0-0.81.9-1.9-0.71.8-0.80.40.80.60.2
Cd content in liver0.20.20.90.8-0.8-0.4-0.2-0.2-0.5-0.2-0.50.2-0.40.2-0.2-0.60.2-0.2-0.9-0.00.0-0.2
Co content in liver0.20.20.6-0.50.50.60.40.40.60.4-0.0-0.50.70.1-0.10.40.10.4-0.5-0.2-0.30.8
Cu content in liver0.30.32.1-0.20.20.40.40.40.40.4-0.0-0.50.9-0.0-0.00.40.00.8-0.9-0.5-0.71.4
Fe content in liver0.70.91.91.2-1.2-1.3-1.1-1.1-1.2-1.1-0.71.4-1.00.4-0.4-0.70.3-0.40.70.20.2-1.2
K content in liver3.63.45.9-1.71.71.41.71.71.21.72.3-1.11.7-2.42.42.0-2.42.2-1.1-2.2-2.10.9
Mg content in liver0.10.10.4-0.20.20.10.30.30.10.30.5-0.10.1-0.60.60.3-0.60.2-0.5-0.2-0.2-0.6
Mn content in liver0.60.61.8-0.70.71.10.90.91.20.90.0-1.30.90.1-0.10.30.3-0.4-1.30.60.70.6
Na content in liver0.70.72.1-0.50.50.10.30.30.00.31.20.20.3-1.41.40.7-1.51.20.4-1.3-1.3-0.4
Rb content in liver0.20.20.60.8-0.8-0.7-0.4-0.4-0.7-0.4-0.30.6-0.20.1-0.1-0.30.20.2-0.5-0.2-0.30.6
Se content in liver0.30.30.80.5-0.5-0.7-0.6-0.6-0.8-0.6-0.10.8-0.1-0.10.10.1-0.20.70.6-0.9-0.90.5
Sr content in liver0.30.30.7-0.70.70.80.60.60.90.60.3-0.80.6-0.10.10.4-0.1-0.1-0.20.30.20.2
Zn content in liver0.50.51.1-0.70.70.50.60.60.50.61.0-0.30.7-1.01.00.7-1.10.8-0.3-0.8-0.8-0.0
Bone: minimum diameter0.61.02.50.8-0.9-1.1-1.1-1.1-1.0-1.0-0.91.0-1.01.0-1.0-0.91.0-1.01.60.90.9-0.8
Time in familiar zone, hab. session 10.40.31.40.1-0.1-0.30.10.1-0.40.10.50.2-0.3-0.70.70.7-0.80.8-0.2-1.2-1.1-0.7
Time in novel zone, hab. session 10.80.82.40.5-0.5-0.4-0.6-0.6-0.3-0.6-0.90.3-0.31.0-1.0-1.41.1-1.40.21.51.50.2
Total zone transitions, hab. session 10.60.81.4-1.21.21.21.01.01.11.00.8-1.11.2-0.60.60.7-0.60.8-0.7-0.6-0.61.0
Total locomotion distance, hab. session 11.21.72.9-1.31.31.51.41.51.51.40.9-1.61.7-0.90.81.1-0.81.3-1.6-0.9-1.01.4
Locomotion velocity, hab. session 11.82.53.6-1.81.81.91.71.81.81.71.4-1.81.9-1.31.31.6-1.21.5-1.4-1.2-1.21.2
Time in familiar zone, hab. session 20.20.20.5-0.70.70.70.60.60.70.60.5-0.70.2-0.30.20.4-0.2-0.0-0.20.30.2-0.3
Time in novel zone, hab. session 21.21.21.81.3-1.3-1.2-1.2-1.2-1.2-1.2-1.31.1-0.81.1-1.1-1.31.1-0.90.50.70.8-0.0
Total zone transitions, hab. session 20.20.31.2-0.20.20.2-0.1-0.10.3-0.1-0.4-0.2-0.00.6-0.6-0.60.6-0.90.41.11.1-0.0
Total locomotion distance, hab. session 20.50.72.0-0.70.70.90.60.71.10.6-0.3-1.00.60.5-0.6-0.60.7-1.0-0.81.41.40.2
Locomotion velocity, hab. session 20.70.92.3-1.21.21.41.11.11.51.10.2-1.41.00.0-0.1-0.00.1-0.4-1.00.90.90.4
Novel to familiar place preference ratio0.20.21.0-0.00.0-0.2-0.1-0.1-0.1-0.1-0.00.2-0.60.1-0.1-0.80.1-0.90.50.70.9-1.0
Novelty place preference0.20.21.1-0.10.1-0.2-0.1-0.0-0.1-0.10.20.2-0.6-0.10.1-0.8-0.1-0.80.50.50.8-1.1
Time in novel zone, NPP test0.60.61.70.3-0.3-0.5-0.5-0.4-0.5-0.5-0.30.6-1.00.3-0.3-1.30.3-1.30.71.01.3-1.3
Total zone transitions, NPP test0.40.51.3-1.11.11.10.80.91.10.80.6-1.00.9-0.50.50.6-0.50.4-0.2-0.0-0.20.2
Total locomotion distance, NPP test0.71.02.8-1.31.31.61.21.21.71.20.4-1.51.2-0.20.10.2-0.1-0.2-0.80.70.60.3
Locomotion velocity, NPP test1.11.53.9-1.71.71.91.51.52.01.50.8-1.81.5-0.60.50.7-0.50.3-0.90.30.10.3
Intraocular pressure0.50.84.90.00.00.50.50.80.60.3-0.5-1.00.80.6-0.6-0.90.9-0.4-2.20.80.81.5
Delta distance traveled before/after self-admin2.02.14.3-1.71.71.51.31.31.51.52.0-1.10.8-2.12.11.4-2.10.60.0-0.9-0.4-1.1
Delta ambulatory time before/after self-admin1.21.52.9-1.61.61.41.21.21.31.41.7-1.10.6-1.71.70.9-1.70.30.0-0.5-0.0-1.0
Parametrial fat weight20.247.467.18.2-8.1-8.0-7.7-7.9-8.0-7.8-7.47.5-7.56.5-6.4-7.26.2-5.75.74.64.5-3.2
Pavlov. Cond. lever latency3.44.28.41.8-1.8-1.4-1.7-1.7-1.2-1.7-2.61.1-1.62.9-2.9-2.32.9-2.60.82.92.5-0.2
Pavlov. Cond. magazine entry latency0.40.51.8-0.00.0-0.3-0.0-0.1-0.5-0.00.90.4-0.0-1.01.00.3-1.01.00.2-1.4-1.20.2
Pavlov. Cond. change in total contacts4.24.59.3-1.81.81.31.81.71.11.82.9-1.01.4-3.03.02.2-3.02.6-1.0-2.9-2.60.2
Pavlov. Cond. index score2.43.07.9-1.11.10.71.11.10.51.12.3-0.41.1-2.62.61.9-2.62.4-0.5-2.8-2.50.2
Pavlov. Cond. latency score3.34.28.9-1.61.61.21.61.51.01.62.7-0.91.4-2.93.02.2-3.02.6-0.8-3.0-2.60.3
Pavlov. Cond. lever contacts1.92.36.4-1.01.00.70.90.90.50.91.8-0.41.0-2.12.21.8-2.22.1-0.4-2.5-2.20.1
Pavlov. Cond. magazine entry number0.50.62.6-0.00.00.3-0.0-0.00.5-0.0-0.9-0.5-0.11.1-1.2-0.51.2-1.20.11.61.5-0.1
Pavlov. Cond. intertrial magazine entries1.11.45.8-0.80.81.00.60.61.30.6-0.6-1.30.21.2-1.2-0.61.3-1.8-0.32.42.2-0.2
Pavlov. Cond. lever-magazine prob. diff.2.63.28.9-1.01.00.61.01.00.41.02.3-0.31.0-2.72.71.9-2.72.5-0.5-3.0-2.70.1
Pavlov. Cond. response bias0.91.24.4-0.20.2-0.10.20.2-0.30.21.30.30.3-1.61.61.1-1.61.7-0.0-2.1-1.90.1
Pavlov. Cond. lever latency4.25.78.0-2.72.72.72.82.82.62.82.3-2.72.8-2.12.01.8-1.91.9-2.1-1.5-1.42.7
Pavlov. Cond. magazine entry latency4.75.79.12.2-2.3-2.0-2.2-2.1-1.8-2.2-2.81.6-2.23.0-3.0-3.03.0-2.91.02.82.8-1.0
Pavlov. Cond. change in total contacts4.06.49.22.9-2.9-2.9-3.0-3.0-2.8-3.0-2.52.9-2.92.2-2.1-1.71.9-1.82.51.41.3-3.0
Pavlov. Cond. index score5.67.59.53.0-3.0-2.9-3.0-3.0-2.8-3.0-2.82.8-3.12.7-2.7-2.62.5-2.72.12.32.2-2.6
Pavlov. Cond. latency score4.25.57.32.6-2.6-2.5-2.6-2.6-2.4-2.6-2.42.4-2.72.3-2.2-2.22.1-2.21.81.91.8-2.5
Pavlov. Cond. lever contacts4.56.28.82.7-2.8-2.8-2.9-2.9-2.7-2.9-2.42.8-3.02.2-2.1-2.02.0-2.12.21.71.7-2.9
Pavlov. Cond. magazine entry number4.65.77.5-2.52.62.32.52.52.22.52.7-2.12.4-2.72.72.5-2.62.5-1.5-2.4-2.21.6
Pavlov. Cond. intertrial magazine entries1.82.64.9-1.51.61.51.61.61.41.62.0-1.21.4-2.22.21.7-2.21.5-1.3-1.6-1.30.2
Pavlov. Cond. lever-magazine prob. diff.5.57.49.63.1-3.1-3.0-3.1-3.1-2.9-3.1-2.82.9-3.12.6-2.5-2.52.4-2.42.02.11.9-2.6
Pavlov. Cond. response bias6.38.610.23.1-3.1-3.0-3.2-3.2-2.8-3.2-3.22.8-3.13.1-3.0-2.92.9-2.92.22.62.5-2.5
Time in closed arm before self-admin0.30.41.20.8-0.8-0.4-0.6-0.5-0.3-0.7-0.90.30.30.8-0.8-0.20.80.1-0.60.2-0.11.1
Time in closed arm after self-admin0.30.32.10.0-0.00.50.30.50.60.1-0.4-0.60.90.5-0.50.10.50.2-1.50.2-0.11.0
Time in open arm before self-admin0.40.51.2-1.01.00.40.30.30.30.61.1-0.2-0.1-0.90.90.6-1.00.21.0-0.5-0.2-0.9
Time in open arm after self-admin0.60.74.50.1-0.1-0.7-0.4-0.7-0.7-0.20.30.8-1.3-0.40.40.2-0.6-0.22.1-0.3-0.1-1.8
Bone: periosteal estimation1.94.05.62.1-2.1-2.0-2.1-2.0-1.9-2.0-2.31.7-1.82.4-2.3-2.22.3-2.11.51.81.9-0.5
Bone: periosteal perimeter0.61.12.20.7-0.7-0.7-0.9-0.9-0.6-0.9-1.00.6-0.91.3-1.3-0.91.3-1.51.21.41.5-0.9
Bone: post-yield work0.10.10.5-0.10.10.00.00.20.10.0-0.1-0.2-0.30.4-0.4-0.20.5-0.4-0.10.70.5-0.0
Progressive ratio test 1 active lever presses0.40.53.10.3-0.3-0.5-0.9-0.9-0.4-1.0-0.70.7-0.60.7-0.7-0.30.6-0.31.80.40.3-0.4
Progressive ratio test 1 breakpoint0.50.63.40.4-0.4-0.6-1.1-1.1-0.6-1.1-0.80.9-0.60.8-0.8-0.30.7-0.41.90.40.3-0.4
Progressive ratio test 1 inactive lever presses0.81.23.60.1-0.1-0.0-0.1-0.30.1-0.5-1.2-0.2-0.51.5-1.6-1.51.6-1.60.61.91.80.2
Progressive ratio test 2 active lever presses0.40.43.7-0.00.0-0.3-0.3-0.7-0.1-0.3-0.60.4-0.50.7-0.7-0.20.6-0.71.90.80.7-0.6
Progressive ratio test 2 breakpoint0.50.64.7-0.10.1-0.3-0.4-0.8-0.1-0.3-0.60.4-0.60.8-0.8-0.20.6-0.82.20.90.7-0.7
Progressive ratio test 2 inactive lever presses2.03.27.80.9-0.9-0.9-1.1-1.4-0.7-1.0-1.90.8-1.52.2-2.2-2.32.2-2.72.02.82.8-0.6
Incentive Sensitization - Responses0.30.51.8-0.40.40.20.3-0.10.30.3-0.2-0.2-0.60.5-0.6-0.40.5-1.21.11.31.3-0.8
Incentive Sensitization - Breakpoint0.50.62.1-0.40.40.10.1-0.20.30.2-0.3-0.1-0.70.6-0.7-0.40.6-1.31.31.41.4-1.1
Sum of active levers in priming session hrs 5-60.30.31.4-0.40.40.60.60.70.60.5-0.0-0.70.70.2-0.20.20.30.4-0.9-0.1-0.31.2
Progressive ratio0.81.35.9-1.21.11.51.31.51.61.20.3-1.71.00.0-0.1-0.20.2-0.6-2.40.90.90.3
Food seeking constrained by brief footshock3.54.37.5-2.62.62.12.01.72.02.02.5-1.71.7-2.32.22.7-2.42.10.6-2.0-2.0-0.2
Seeking ratio, punishment vs. effort0.91.28.20.00.0-0.7-0.6-0.8-0.8-0.40.71.1-0.6-0.90.91.3-1.11.12.9-1.4-1.4-1.2
Retroperitoneal fat weight20.788.4137.811.7-11.7-11.4-11.2-10.9-11.4-11.2-9.810.9-10.28.6-8.3-9.38.1-6.96.55.45.2-3.7
Reaction time number correct0.40.83.1-0.90.91.20.70.91.10.80.4-1.11.0-0.10.1-0.70.1-0.7-1.11.01.11.8
Reaction time mean minus median1.12.73.91.4-1.4-1.8-1.8-1.7-1.8-1.8-1.61.6-1.91.8-1.8-2.01.7-1.62.01.31.3-1.1
Reaction time mean minus median AUC1.23.15.51.4-1.4-1.7-1.8-1.7-1.7-1.8-1.71.5-2.01.9-1.9-2.31.9-2.01.91.71.8-1.1
Reaction time num false alarms1.21.73.9-1.31.31.61.41.41.61.60.8-1.52.0-0.80.71.3-0.71.2-0.8-0.8-0.91.6
Reaction time num false alarms AUC1.01.53.1-1.31.31.61.41.41.51.60.9-1.51.8-0.90.81.2-0.81.1-0.8-0.8-0.81.3
Reaction time trials correct on left0.40.83.1-0.90.91.20.70.91.10.80.4-1.11.0-0.10.1-0.70.1-0.7-1.11.01.11.8
Reaction time trials on left0.40.82.8-0.80.81.10.70.81.10.80.3-1.10.9-0.10.0-0.80.2-0.8-1.11.11.31.7
Reaction time mean3.55.56.92.5-2.5-2.5-2.5-2.6-2.5-2.6-2.62.4-2.62.4-2.3-2.32.2-2.22.31.81.8-1.8
Reaction time mean AUC2.84.56.02.4-2.4-2.4-2.4-2.3-2.3-2.5-2.42.2-2.32.2-2.1-2.12.0-1.91.81.41.5-1.4
Median of all reaction times3.34.76.12.5-2.4-2.3-2.3-2.4-2.3-2.4-2.52.3-2.42.1-2.1-1.92.0-2.02.01.61.6-1.8
Reaction time omissions1.31.84.61.2-1.3-1.1-1.2-1.0-1.1-1.2-1.30.9-1.41.3-1.3-2.11.4-1.90.11.71.9-0.6
Reaction time false alarm rate0.50.71.7-0.70.80.90.90.80.91.00.6-0.81.1-0.60.61.3-0.71.1-0.2-0.9-1.00.3
Reaction time premature initiation rate0.10.10.40.1-0.10.1-0.1-0.20.1-0.3-0.6-0.10.30.6-0.60.10.5-0.10.40.20.10.6
Reaction time premature initiations0.20.42.9-0.40.30.70.30.40.70.2-0.3-0.70.90.5-0.6-0.20.6-0.3-0.40.60.61.7
Std. dev. reaction times2.03.74.81.9-1.9-2.1-2.1-2.0-2.1-2.1-2.01.9-2.22.0-2.0-2.11.9-1.81.91.51.5-1.4
Reaction time trials completed0.40.82.8-0.80.81.10.70.81.10.80.3-1.10.9-0.10.0-0.80.2-0.8-1.11.11.31.7
Reaction time trials AUC0.50.93.5-0.70.71.10.60.81.10.70.1-1.10.90.2-0.3-1.00.5-1.0-1.11.31.51.9
Run reversals in cocaine runway, females1.81.84.01.7-1.6-1.5-1.6-1.6-1.5-1.5-0.81.6-2.00.6-0.5-0.90.4-1.11.40.70.9-2.0
Run reversals in cocaine runway, males1.21.27.50.6-0.6-1.3-1.1-1.3-1.4-1.0-0.11.5-1.00.00.00.4-0.20.42.7-0.8-0.8-1.4
Latency to leave start box in cocaine runway0.50.63.70.4-0.30.30.50.60.40.4-0.6-0.70.80.4-0.4-0.80.5-0.2-1.90.50.41.7
Latency to leave start box in cocaine runway, F0.70.92.11.1-1.1-0.5-0.4-0.4-0.4-0.4-1.50.20.01.1-1.1-1.41.3-0.8-0.61.00.91.3
Latency to leave start box in cocaine runway, M1.21.15.6-0.80.81.21.31.51.31.00.6-1.41.2-0.60.60.3-0.40.4-2.4-0.2-0.11.2
Std. dev. time between licks in bursts0.60.91.9-1.21.21.11.11.11.01.11.4-1.00.8-1.11.10.4-1.00.5-0.6-0.4-0.40.0
Total sessions with >9 infusions0.60.86.8-0.20.2-0.2-0.3-0.6-0.1-0.3-0.30.4-0.80.6-0.6-0.20.4-0.92.60.90.8-1.8
Short access day 1 total inactive lever presses0.91.23.00.2-0.20.20.60.20.40.1-1.2-0.70.31.5-1.6-1.41.7-1.2-0.81.71.51.7
Short access day 10 total inactive lever presses1.33.28.21.3-1.3-0.6-0.1-0.5-0.5-0.5-2.1-0.3-0.52.3-2.3-2.92.6-2.2-1.92.52.42.3
Short access day 1 total infusions0.60.82.2-1.51.51.21.31.01.31.10.7-1.20.6-0.40.30.5-0.4-0.20.60.40.4-0.6
Short access day 10 total infusions0.40.52.40.3-0.3-0.3-0.4-0.7-0.2-0.4-0.80.4-0.40.9-0.9-0.60.8-0.71.60.80.7-0.4
Short access total infusions0.40.64.1-0.10.1-0.2-0.3-0.5-0.1-0.3-0.50.3-0.70.6-0.6-0.40.5-0.92.00.90.8-1.3
Short access day 1 locomotion0.30.33.0-0.60.60.20.2-0.20.20.10.30.0-0.3-0.20.10.2-0.2-0.41.70.30.4-1.4
Short access day 10 total locomotion0.30.51.3-1.11.10.90.70.30.91.10.6-0.70.6-0.40.40.4-0.40.11.00.10.1-0.1
Short access total locomotion0.70.93.7-1.31.30.70.80.20.70.81.1-0.40.4-1.01.01.0-1.10.51.9-0.5-0.4-0.7
One hour access (0.3 mA shock)0.30.41.0-1.01.00.80.70.41.01.00.2-0.90.10.1-0.20.40.1-0.40.50.60.5-0.4
Compulsive drug intake2.73.26.8-1.91.91.82.22.21.82.21.8-2.21.5-1.61.51.6-1.41.4-2.6-1.1-1.21.1
One hour access (shock baseline)0.60.96.60.4-0.4-0.7-0.8-1.2-0.6-0.5-0.80.8-0.90.9-0.9-0.50.7-0.82.60.80.7-1.2
Social response proportion3.94.48.62.9-2.9-2.7-2.4-2.3-2.8-2.3-2.22.3-2.41.9-1.8-2.21.8-1.50.41.01.1-0.4
Social responses0.50.61.41.1-1.2-0.9-1.1-1.0-1.0-0.9-0.91.0-0.50.7-0.7-0.50.6-0.30.30.20.10.1
Social time1.01.43.01.4-1.4-1.5-1.7-1.7-1.6-1.5-0.91.7-1.20.6-0.6-1.10.6-0.41.70.20.2-0.0
Soleus weight0.20.51.21.0-0.9-0.5-0.3-0.3-0.5-0.4-0.80.1-0.30.8-0.8-1.10.9-0.6-1.00.60.60.6
Bone: stiffness0.20.31.00.4-0.4-0.5-0.4-0.3-0.4-0.4-0.40.4-0.40.6-0.5-1.00.6-0.70.30.80.7-0.2
Tibialis anterior weight0.72.43.51.9-1.9-1.9-1.5-1.6-1.9-1.5-1.61.5-1.91.6-1.6-1.81.6-1.50.51.01.1-0.9
Time to tail flick, vehicle, before self-admin4.34.48.82.5-2.5-1.9-1.9-1.7-1.7-2.1-2.91.4-1.42.8-2.8-2.43.0-1.8-0.72.01.71.3
Time to tail flick, vehicle, after self-admin0.50.75.10.8-0.8-0.5-0.3-0.3-0.5-0.5-0.90.20.60.9-0.9-0.30.90.7-0.7-0.4-0.92.3
Time to tail flick, test, before self-admin0.30.40.7-0.80.80.40.60.60.40.70.4-0.80.60.0-0.10.8-0.00.7-0.1-0.5-0.80.7
Time to tail flick, test, after self-admin1.11.13.2-0.10.10.3-0.10.10.40.0-1.2-0.70.11.7-1.7-1.11.8-1.3-0.21.81.51.3
Delta time to tail flick, vehicle, before/after SA0.90.81.4-1.11.10.91.20.90.91.10.9-0.91.2-0.70.70.9-0.80.9-0.2-0.7-0.90.6
Delta time to tail flick, test, before/after SA0.60.72.00.5-0.5-0.1-0.4-0.4-0.1-0.5-1.00.2-0.31.0-1.0-1.21.1-1.2-0.01.31.40.6
Tibia length2.56.911.23.1-3.1-3.2-3.3-3.3-3.2-3.3-2.93.1-2.42.7-2.6-1.92.5-1.12.80.80.6-0.7
Ambulatory time before self-admin0.40.53.00.6-0.6-0.9-0.9-0.9-1.0-1.0-0.21.1-0.60.2-0.20.10.10.31.7-0.4-0.6-0.1
Ambulatory time after self-admin1.21.43.7-1.21.20.90.80.70.70.81.8-0.40.6-1.91.91.4-1.91.10.9-1.3-1.0-0.5
Bone: tissue strength0.60.63.20.6-0.6-0.8-0.9-0.8-0.7-0.8-0.50.9-1.00.4-0.3-0.20.2-0.41.10.10.2-1.8
Total heroin consumption0.60.71.90.2-0.2-0.00.10.00.0-0.1-0.9-0.3-0.31.2-1.2-1.01.3-1.1-0.81.41.20.8
Bone: trabecular number0.30.51.2-0.60.50.50.70.80.40.70.9-0.50.6-0.90.80.5-0.80.7-1.1-0.9-0.70.5
Bone: trabecular spacing1.41.83.31.5-1.5-1.6-1.6-1.6-1.5-1.6-1.31.5-1.61.2-1.2-0.81.1-0.81.80.80.6-1.2
Bone: trabecular thickness0.20.31.2-0.30.30.30.40.40.20.30.5-0.10.5-0.70.60.3-0.60.7-0.6-0.8-0.71.1
Bone: trabecular tissue density0.30.42.50.0-0.0-0.3-0.3-0.3-0.4-0.30.60.6-0.6-0.80.80.3-0.90.41.1-0.6-0.5-1.6
Water consumed over 24 hours0.81.02.70.6-0.6-0.4-0.7-0.7-0.4-0.7-1.70.3-0.41.6-1.6-1.01.6-1.30.61.21.40.1
Number of responses in last shaping day0.40.41.2-0.90.91.00.70.71.10.40.0-0.90.60.3-0.40.20.3-0.40.20.80.60.5