RT1-T24-2

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 BLA gene expression RT1-T24-2 0.23 0.11 1.9e-10 0.15 0.17 0.15 0.16 2.4e-08 1.6e-09 2.3e-08 8.1e-09
2 LHb gene expression RT1-T24-2 0.18 0.13 3.2e-03 0.07 0.11 0.04 0.09 1.2e-02 1.6e-03 4.8e-02 3.5e-03
3 PL gene expression RT1-T24-2 0.15 0.07 0.0e+00 0.18 0.17 0.17 0.18 2.9e-19 1.6e-18 1.4e-18 2.7e-19
4 OFC gene expression RT1-T24-2 0.2 0.13 3.1e-03 0.04 0.04 0.01 0.03 3.5e-02 5.0e-02 1.9e-01 6.0e-02
5 IL gene expression RT1-T24-2 0.17 0.11 3.7e-03 0.06 0.02 0.01 0.01 1.3e-02 9.8e-02 1.7e-01 1.4e-01
6 Liver gene expression RT1-T24-2 0.16 0.1 7.8e-16 0.12 0.11 0.12 0.12 2.5e-13 1.5e-12 2.1e-13 3.6e-13
7 Adipose gene expression RT1-T24-2 0.86 0.01 0.0e+00 0.62 0.61 0.62 0.63 7.8e-87 9.7e-85 1.8e-88 1.9e-89
8 pVTA gene expression RT1-T24-2 0.09 0.08 3.7e-03 0.01 0.04 0.05 0.03 1.6e-01 6.5e-03 4.0e-03 2.4e-02
9 Brain gene expression RT1-T24-2 0.06 0.05 1.5e-04 0.01 0.03 0.03 0.03 4.1e-02 4.8e-04 4.8e-04 7.6e-04

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9
Bone: apparent density1.52.55.32.01.81.7-1.7-1.70.9-0.90.1-2.3
Area under the delay curve2.12.23.0-1.0-1.3-1.51.61.5-1.71.61.31.7
BMI with tail1.85.97.6-1.7-2.4-2.62.82.7-2.62.62.51.5
BMI without tail3.67.49.4-2.6-3.0-3.13.03.0-2.62.62.42.0
Body weight6.527.034.0-5.4-5.8-5.85.85.8-4.64.54.64.1
Weight adjusted by age2.93.35.2-2.2-2.3-1.91.91.9-1.61.41.01.9
Bone surface0.10.20.5-0.7-0.6-0.50.50.5-0.20.10.30.2
Bone volume0.10.20.9-0.0-0.2-0.30.30.3-0.50.41.0-0.3
Breakpoint value in progressive ratio session1.01.11.50.91.21.2-1.1-1.11.0-1.0-1.2-0.6
Number of licking bursts0.40.52.2-0.20.20.4-0.4-0.41.0-0.9-1.50.4
Context. condit. distance diff. score6.07.212.41.02.22.6-2.6-2.63.5-3.5-3.4-1.8
Locomotion velocity, session 10.20.20.5-0.10.20.4-0.4-0.40.7-0.7-0.5-0.3
Locomotion distance, session 10.50.61.51.20.90.8-0.8-0.8-0.00.00.4-1.1
Locomotion velocity, session 20.00.00.1-0.3-0.10.0-0.0-0.00.3-0.3-0.40.2
Locomotion distance, session 20.40.51.30.80.70.8-0.8-0.80.5-0.50.1-1.1
Locomotion velocity, session 30.10.20.50.40.0-0.10.10.1-0.60.60.7-0.2
Locomotion distance, session 31.61.72.91.41.41.4-1.4-1.41.1-1.1-0.6-1.7
Stereotopy head waving bouts, day 31.72.03.9-2.0-1.7-1.61.51.5-0.70.70.11.8
Stereotopy head waving duration, day 31.21.52.5-1.6-1.5-1.31.31.3-0.70.70.21.6
Locomotion velocity, session 74.44.85.91.92.32.4-2.4-2.42.2-2.1-1.6-2.2
Locomotion distance, session 74.15.26.52.42.52.5-2.5-2.52.0-1.9-1.6-2.3
Stereotopy head waving bouts, day 72.12.42.9-1.4-1.6-1.71.71.7-1.41.41.31.5
Stereotopy head waving duration, day 72.83.44.2-1.9-2.0-2.02.02.0-1.61.61.51.7
Locomotion velocity, session 81.11.34.0-1.6-0.6-0.10.00.01.5-1.5-2.00.9
Locomotion distance, session 83.24.77.81.01.82.1-2.1-2.22.8-2.8-2.3-1.9
Degree of sensitization distance0.60.62.0-0.00.40.5-0.6-0.61.0-1.0-1.40.2
Degree of sensitization stereotypy1.41.51.9-1.0-1.3-1.31.41.4-1.21.21.21.1
Conditioned locomotion0.60.71.4-1.2-1.1-1.01.01.0-0.50.50.40.6
Cocaine response after cond. corrected0.50.50.70.80.80.8-0.8-0.80.5-0.6-0.7-0.5
Cocaine response after cond. not corrected0.30.30.9-0.8-0.5-0.40.40.40.1-0.1-0.60.9
Cocaine response before conditioning5.06.09.7-3.1-2.9-2.82.72.7-1.41.40.73.0
Saline control response1.41.85.4-0.2-0.9-1.11.11.1-1.81.72.30.2
Bone: connectivity density2.74.25.82.02.22.3-2.3-2.31.9-1.9-1.0-2.4
Bone: cortical apparent density0.81.13.40.5-0.2-0.50.50.5-1.61.61.80.3
Bone: cortical area2.23.44.1-1.7-2.0-2.02.02.0-1.81.81.61.5
Bone: cortical porosity0.50.61.1-0.3-0.6-0.70.70.7-1.01.00.60.9
Bone: cortical porosity0.70.81.6-1.0-1.0-1.00.90.9-0.60.70.11.3
Bone: cortical thickness3.55.711.6-0.5-1.7-2.12.12.1-3.33.33.41.2
Bone: cortical thickness1.21.44.60.6-0.2-0.60.60.6-1.71.72.2-0.2
Bone: cortical tissue density0.60.82.70.5-0.2-0.50.50.5-1.41.41.60.3
Condit. Reinf. active minus inactive responses0.91.01.70.81.01.1-1.2-1.21.0-1.0-0.4-1.3
Condit. Reinf. active-inactive response ratio0.10.10.10.30.10.1-0.2-0.2-0.30.30.4-0.2
Condit. Reinf. active responses1.41.73.41.21.41.4-1.4-1.41.1-1.1-0.2-1.8
Condit. Reinf. inactive responses2.12.55.21.91.81.7-1.6-1.61.1-1.10.2-2.3
Incentive salience index mean1.51.83.20.51.11.3-1.4-1.41.8-1.8-1.2-1.4
Condit. Reinf. lever presses2.53.46.30.61.41.8-1.7-1.72.5-2.5-1.9-1.7
Condit. Reinf. active minus inactive responses1.31.62.2-1.4-1.4-1.51.51.5-1.01.00.31.5
Condit. Reinf. active-inactive response ratio2.93.04.5-2.0-2.0-2.02.02.0-1.21.20.42.1
Condit. Reinf. active responses0.00.00.0-0.1-0.0-0.10.00.10.1-0.1-0.20.1
Condit. Reinf. inactive responses1.72.03.21.41.61.6-1.6-1.61.2-1.2-0.5-1.8
Condit. Reinf. lever presses0.40.60.70.70.80.8-0.8-0.80.7-0.6-0.8-0.8
Condit. Reinf. lever reinforcers received0.00.10.30.00.10.1-0.1-0.10.3-0.3-0.60.0
Conditioned reinforcement - actives0.40.40.8-0.4-0.5-0.60.30.4-0.80.90.10.9
Conditioned reinforcement - inactives1.31.53.2-0.4-0.9-1.11.01.0-1.81.81.50.7
Conditioned locomotion0.20.20.8-0.3-0.2-0.0-0.2-0.2-0.10.2-0.80.9
Patch foraging indifference point 0 sec0.60.92.60.5-0.2-0.50.40.5-1.51.51.6-0.1
Patch foraging indifference point AUC2.52.83.9-1.7-1.8-1.92.02.0-1.61.60.81.6
Delay disc. indifference point, 0s delay0.40.51.2-0.9-0.8-0.60.60.6-0.40.5-0.11.1
Delay disc. indifference point, 16s delay1.81.84.20.2-0.6-1.01.21.2-2.12.01.80.7
Delay disc. indifference point, 2s delay2.12.35.5-1.7-1.7-1.61.51.5-1.31.20.32.3
Delay disc. indifference point, 24s delay0.60.61.2-0.2-0.5-0.70.80.9-1.11.10.70.5
Delay disc. indifference point, 4s delay2.93.14.3-2.0-2.0-1.91.91.8-1.41.41.22.1
Delay disc. indifference point, 8s delay0.40.40.8-0.4-0.5-0.60.60.6-0.70.60.90.6
Indifference point function ln k0.50.71.50.20.50.8-0.8-0.81.2-1.2-1.2-0.4
Indifference point function log k0.50.71.50.20.50.8-0.8-0.81.2-1.2-1.2-0.4
Patch foraging total patch changes 0 sec0.81.33.80.5-0.3-0.70.60.6-1.81.82.0-0.1
Patch foraging total patch changes 12 sec1.01.33.20.3-0.5-0.80.90.9-1.81.71.50.5
Patch foraging total patch changes 18 sec0.91.22.81.40.4-0.00.10.1-1.51.61.7-0.9
Patch foraging total patch changes 24 sec1.21.54.72.21.31.0-1.0-1.0-0.90.91.0-1.1
Patch foraging total patch changes 6 sec0.91.33.80.8-0.1-0.60.50.6-1.92.01.5-0.3
Patch foraging time to switch 0 sec0.50.72.01.41.00.9-0.9-0.9-0.10.10.5-0.9
Patch foraging water rate 0 sec0.40.61.1-0.6-0.8-1.10.90.9-0.80.70.10.8
Patch foraging water rate 12 sec0.10.20.60.80.50.2-0.4-0.4-0.10.10.5-0.8
Patch foraging water rate 18 sec0.30.41.2-0.6-0.7-0.70.50.5-0.40.41.1-0.2
Patch foraging water rate 24 sec1.52.13.1-1.2-1.5-1.81.61.6-1.41.41.50.9
Patch foraging water rate 6 sec0.00.10.20.40.1-0.1-0.0-0.0-0.20.10.3-0.5
Seeking ratio, delayed vs. immediate footshock0.40.50.8-0.7-0.8-0.70.70.7-0.80.70.90.3
Distance traveled before self-admin0.10.10.5-0.5-0.2-0.10.10.10.5-0.3-0.70.1
Distance traveled after self-admin0.40.41.0-1.0-0.7-0.70.80.80.1-0.00.30.6
Extensor digitorum longus weight0.10.31.0-1.0-0.6-0.40.30.30.3-0.3-0.70.4
Bone: elastic displacement0.20.31.10.3-0.1-0.20.20.2-0.70.71.0-0.0
Bone: elastic work1.92.53.3-1.1-1.5-1.61.61.6-1.81.81.71.3
Bone: endosteal estimation2.55.515.4-3.9-2.9-2.42.42.4-0.20.1-0.72.7
Bone: endosteal perimeter1.02.05.2-2.3-1.1-0.50.50.51.5-1.5-2.21.1
Epididymis fat weight3.17.221.11.7-0.4-1.51.61.6-4.14.14.60.1
Delta time in closed arm before/after self-admin0.20.20.9-0.4-0.4-0.40.40.4-0.30.1-0.30.9
Delta time in open arm before/after self-admin0.20.21.30.1-0.1-0.20.10.1-0.30.41.1-0.4
Diff in mean of infusions in LGA sessions3.84.25.62.32.42.2-2.3-2.31.7-1.6-1.9-1.9
Delay discount exponential model param2.02.12.91.01.31.5-1.5-1.51.7-1.6-1.2-1.7
Extinction: sum of active levers before priming0.60.61.01.00.90.8-0.9-0.90.4-0.4-0.6-0.4
Active lever presses in extinction session 60.10.10.40.70.40.1-0.0-0.0-0.20.10.2-0.3
Bone: final force6.19.813.0-2.2-3.1-3.33.33.3-3.63.53.12.4
Bone: final moment5.59.011.5-2.2-3.0-3.23.23.2-3.43.33.12.2
Food consumed during 24 hour testing period0.80.92.3-1.5-1.2-1.11.11.1-0.20.30.70.7
Glucose1.72.68.7-1.40.00.6-0.5-0.52.5-2.4-2.90.6
Heart weight0.30.52.3-0.5-0.5-0.40.40.4-0.20.2-0.81.5
Delay discount hyperbolic model param2.12.23.31.21.41.5-1.6-1.51.6-1.5-1.1-1.8
Intermittent access intake day 1-15 change0.80.82.1-0.8-0.9-1.01.01.0-0.70.61.4-0.0
Intermittent access intake escalation0.40.40.8-0.9-0.7-0.70.70.7-0.00.00.80.0
Intermittent access intake escalation 20.60.61.8-1.3-0.6-0.40.40.41.0-1.0-0.4-0.1
Intermitt. access day 1 inactive lever presses0.40.51.3-0.9-0.6-0.50.50.5-0.0-0.1-1.10.9
Intermitt. access day 15 inactive lever presses2.52.73.8-1.4-1.7-1.91.91.9-1.71.61.21.4
Intermitt. access escalation Index3.43.04.01.51.82.0-1.9-2.01.7-1.6-1.7-1.3
Intermittent access day 1 total infusions0.50.61.20.90.91.0-1.1-1.10.1-0.1-0.0-0.3
Intermittent access day 15 total infusions0.10.10.40.30.30.4-0.5-0.5-0.10.00.6-0.3
Intermittent access terminal intake (last 3 days)0.10.10.4-0.0-0.1-0.10.00.1-0.50.40.60.3
Intermittent access total infusions0.10.10.10.30.20.3-0.4-0.4-0.30.30.3-0.0
Intermittent access day 1 locomotion0.20.20.60.10.30.7-0.8-0.80.2-0.10.2-0.1
Intermittent access day 15 total locomotion0.80.92.2-1.5-1.2-1.00.80.9-0.50.41.00.8
Intermittent access total locomotion0.60.61.5-1.2-1.0-0.70.70.7-0.40.51.10.6
Intermittent access standard deviation2.62.83.7-1.0-1.5-1.81.81.8-1.91.81.91.2
Left kidney weight4.011.113.7-3.2-3.7-3.73.63.6-3.13.03.22.9
Right kidney weight3.49.713.0-3.5-3.6-3.53.43.4-2.42.42.92.6
Cocaine induced anxiety2.52.84.90.61.31.7-1.7-1.72.2-2.1-1.7-1.7
Post-drug Anxiety1.11.23.70.30.70.9-0.9-0.91.4-1.4-1.9-0.6
Baseline Anxiety0.20.20.50.50.1-0.20.30.3-0.50.5-0.60.7
Tail length4.714.128.6-5.3-4.7-4.34.24.1-1.91.91.53.8
Length with tail4.416.227.2-5.2-4.9-4.54.54.5-2.62.52.53.9
Length without tail3.37.29.6-3.1-3.1-2.93.03.0-2.01.91.72.9
Times rat made contact with spout1.72.04.52.01.61.4-1.4-1.40.3-0.31.0-2.1
Lifetime Intake0.10.10.10.20.10.3-0.4-0.4-0.40.40.10.3
Liver weight, left0.50.82.8-1.7-1.2-1.00.91.0-0.10.10.50.6
Liver weight, right3.55.813.3-3.6-3.0-2.62.62.6-0.80.80.32.8
Locomotor activity1.32.06.5-2.5-1.8-1.41.41.40.0-0.0-0.41.6
Locomotor testing distance0.20.31.0-1.0-0.7-0.40.40.40.1-0.1-0.60.7
Locomotor testing rearing0.50.82.3-1.5-1.1-0.80.90.9-0.20.2-0.11.1
Locomotion in novel chamber0.70.81.0-0.9-1.0-1.01.00.9-0.90.70.90.8
Locomotion in novel chamber post-restriction0.60.71.0-0.5-0.8-1.01.01.0-1.00.90.80.7
Fecal boli incidents, locomotor time 10.80.91.30.91.01.1-1.0-1.10.9-1.0-0.8-0.8
Change in fecal boli incidents, locomotor task0.90.92.7-0.9-0.8-0.90.91.0-0.60.4-0.71.7
Time >=10cm from walls, locomotor time 10.80.81.8-1.3-1.0-0.80.80.9-0.10.1-0.81.3
Bouts of movement, locomotor time 11.11.21.90.40.91.1-1.0-1.01.4-1.4-0.9-1.3
Total resting periods, locomotor time 10.50.51.10.00.50.7-0.6-0.61.1-1.0-0.6-0.8
Rest time, locomotor task time 10.20.20.9-1.0-0.4-0.20.30.20.6-0.6-0.40.1
Distance moved, locomotor task time 10.60.61.3-0.1-0.6-0.70.70.7-1.11.10.80.5
Vertical activity count, locomotor time 10.30.30.60.1-0.3-0.40.40.4-0.80.80.70.4
Time >=10cm from walls, locomotor time 20.20.20.9-0.6-0.3-0.00.10.10.3-0.1-0.90.8
Bouts of movement, locomotor time 20.70.72.8-1.7-1.2-0.70.80.70.2-0.20.20.8
Total resting periods, locomotor time 20.60.72.8-1.7-1.0-0.50.60.60.6-0.6-0.30.8
Rest time, locomotor task time 20.91.02.9-1.3-0.30.10.0-0.01.7-1.7-1.3-0.0
Distance moved, locomotor task time 20.70.82.50.4-0.3-0.60.50.5-1.51.61.00.5
Vertical activity count, locomotor time 20.10.10.40.60.2-0.00.00.0-0.50.50.10.2
Light reinforcement 10.10.20.40.3-0.1-0.30.20.2-0.60.60.50.4
Light reinforcement 20.71.01.6-1.2-1.1-1.01.11.1-0.50.51.20.7
Bone: marrow area2.55.415.2-3.9-2.9-2.42.42.4-0.20.2-0.72.7
Bone: maximum diameter0.71.44.5-2.1-1.4-1.11.11.10.3-0.3-0.71.2
Bone: maximum force5.28.910.7-2.3-3.0-3.23.23.2-3.33.23.12.2
Bone: maximum moment4.78.29.5-2.3-3.0-3.13.13.1-3.13.03.02.0
Mean time between licks in bursts0.71.02.3-1.3-0.40.0-0.0-0.01.5-1.5-1.50.4
Mean num. licks in bursts0.91.14.41.20.50.3-0.3-0.3-0.80.72.1-1.5
Cd content in liver0.70.83.00.0-0.4-0.60.80.7-1.11.11.7-0.2
Co content in liver1.41.63.4-0.2-0.9-1.11.21.2-1.91.81.51.0
Cu content in liver3.34.08.12.82.52.2-2.3-2.31.0-1.1-0.3-2.1
Fe content in liver0.50.61.20.0-0.4-0.70.60.7-1.01.11.10.4
K content in liver0.20.20.40.40.40.4-0.3-0.30.3-0.3-0.60.3
Mg content in liver2.42.55.80.41.21.5-1.4-1.52.1-2.1-2.4-0.3
Mn content in liver2.32.69.5-0.90.30.8-0.9-1.02.3-2.3-3.10.5
Na content in liver0.10.10.20.1-0.1-0.20.10.1-0.50.50.40.4
Rb content in liver0.81.11.51.11.21.1-1.0-0.91.1-1.0-0.9-0.9
Se content in liver1.51.86.3-0.80.30.8-0.7-0.72.0-2.0-2.50.2
Sr content in liver0.70.71.7-1.2-1.0-0.70.60.6-0.40.3-0.51.3
Zn content in liver0.10.10.6-0.10.00.2-0.3-0.30.2-0.2-0.70.7
Bone: minimum diameter0.91.75.7-2.4-1.6-1.21.21.20.4-0.4-0.91.4
Time in familiar zone, hab. session 13.53.36.62.62.22.0-2.0-2.00.7-0.70.2-2.3
Time in novel zone, hab. session 11.91.94.1-2.0-1.6-1.41.41.4-0.30.3-0.51.9
Total zone transitions, hab. session 10.70.92.01.01.01.0-1.0-1.00.7-0.7-0.2-1.4
Total locomotion distance, hab. session 10.60.81.41.01.01.0-1.0-1.00.6-0.6-0.2-1.2
Locomotion velocity, hab. session 10.30.40.80.90.70.7-0.7-0.70.2-0.20.2-0.9
Time in familiar zone, hab. session 20.30.30.80.90.70.6-0.7-0.70.1-0.10.3-0.6
Time in novel zone, hab. session 20.30.30.5-0.7-0.7-0.60.70.7-0.40.40.40.4
Total zone transitions, hab. session 20.10.10.30.40.20.1-0.1-0.1-0.30.30.5-0.3
Total locomotion distance, hab. session 21.11.42.01.41.41.4-1.4-1.40.8-0.8-0.4-1.4
Locomotion velocity, hab. session 21.21.62.11.41.41.4-1.4-1.40.9-0.9-0.6-1.4
Novel to familiar place preference ratio0.00.00.10.30.10.0-0.0-0.0-0.30.30.2-0.1
Novelty place preference0.10.10.2-0.0-0.2-0.20.20.2-0.40.50.20.1
Time in novel zone, NPP test0.10.20.3-0.2-0.4-0.40.40.4-0.50.50.30.3
Total zone transitions, NPP test1.21.73.41.21.41.4-1.4-1.41.1-1.1-0.3-1.8
Total locomotion distance, NPP test1.31.73.31.61.51.4-1.4-1.40.8-0.8-0.1-1.8
Locomotion velocity, NPP test2.12.94.82.02.01.9-1.9-1.91.2-1.2-0.4-2.2
Intraocular pressure1.11.54.51.11.21.2-1.1-1.21.1-1.10.3-2.1
Delta distance traveled before/after self-admin1.41.52.4-1.0-1.2-1.31.31.3-1.11.11.61.0
Delta ambulatory time before/after self-admin0.50.60.8-0.9-0.8-0.80.80.8-0.40.50.70.9
Parametrial fat weight2.14.06.0-1.5-2.1-2.12.12.1-2.12.02.51.4
Pavlov. Cond. lever latency1.01.33.40.6-0.4-0.70.70.7-1.81.81.80.3
Pavlov. Cond. magazine entry latency1.31.64.1-0.40.50.9-0.9-0.92.0-2.0-1.8-0.7
Pavlov. Cond. change in total contacts0.60.72.4-1.6-1.0-0.80.80.80.2-0.2-0.20.7
Pavlov. Cond. index score1.51.94.8-0.60.50.9-0.8-0.82.2-2.1-2.1-0.6
Pavlov. Cond. latency score1.01.33.6-0.90.20.6-0.5-0.51.9-1.8-1.8-0.3
Pavlov. Cond. lever contacts0.60.82.0-1.0-0.10.2-0.1-0.11.4-1.4-1.40.0
Pavlov. Cond. magazine entry number1.72.24.5-0.2-1.0-1.31.31.3-2.12.11.81.2
Pavlov. Cond. intertrial magazine entries0.70.92.51.61.00.8-0.8-0.8-0.30.20.9-1.3
Pavlov. Cond. lever-magazine prob. diff.1.62.05.0-0.50.61.0-0.9-0.92.2-2.2-2.0-0.7
Pavlov. Cond. response bias1.72.15.1-0.30.71.1-1.0-1.02.3-2.2-2.0-1.0
Pavlov. Cond. lever latency0.30.30.7-0.7-0.7-0.60.60.6-0.40.40.10.8
Pavlov. Cond. magazine entry latency0.60.71.0-1.0-1.0-0.90.90.9-0.50.50.30.8
Pavlov. Cond. change in total contacts0.20.30.9-0.0-0.4-0.50.40.5-0.70.71.0-0.0
Pavlov. Cond. index score0.00.00.1-0.0-0.1-0.10.10.1-0.10.10.3-0.2
Pavlov. Cond. latency score0.10.10.2-0.1-0.3-0.30.30.3-0.30.30.5-0.0
Pavlov. Cond. lever contacts0.20.30.90.90.50.4-0.4-0.4-0.20.20.7-1.0
Pavlov. Cond. magazine entry number0.30.40.60.60.70.7-0.7-0.70.6-0.6-0.8-0.4
Pavlov. Cond. intertrial magazine entries1.52.04.40.10.91.2-1.2-1.22.0-2.0-2.1-0.7
Pavlov. Cond. lever-magazine prob. diff.0.00.00.1-0.0-0.1-0.10.10.1-0.10.10.4-0.3
Pavlov. Cond. response bias0.10.20.60.40.30.3-0.3-0.30.1-0.10.4-0.8
Time in closed arm before self-admin0.00.00.20.20.10.00.00.00.0-0.0-0.4-0.0
Time in closed arm after self-admin0.70.81.4-0.3-0.7-0.91.01.0-1.21.00.41.0
Time in open arm before self-admin0.20.20.6-0.20.20.5-0.6-0.60.8-0.6-0.1-0.5
Time in open arm after self-admin0.60.71.20.30.70.9-1.1-1.11.0-0.70.3-1.1
Bone: periosteal estimation2.85.711.4-3.4-3.0-2.72.72.7-1.21.20.62.5
Bone: periosteal perimeter1.32.15.5-2.3-1.8-1.61.61.6-0.30.3-0.21.6
Bone: post-yield work0.30.41.0-1.0-0.4-0.10.10.10.9-0.9-0.7-0.3
Progressive ratio test 1 active lever presses0.20.20.60.50.50.7-0.8-0.7-0.10.1-0.30.2
Progressive ratio test 1 breakpoint0.20.30.60.60.50.7-0.7-0.7-0.20.2-0.30.3
Progressive ratio test 1 inactive lever presses0.20.20.50.70.40.1-0.1-0.1-0.60.70.3-0.4
Progressive ratio test 2 active lever presses0.70.81.41.01.01.1-1.2-1.20.4-0.40.0-0.8
Progressive ratio test 2 breakpoint1.21.42.21.41.31.4-1.5-1.50.6-0.60.1-1.3
Progressive ratio test 2 inactive lever presses0.30.40.7-0.7-0.7-0.50.40.4-0.70.70.80.4
Incentive Sensitization - Responses0.70.70.90.90.90.9-0.9-0.90.7-0.80.0-0.9
Incentive Sensitization - Breakpoint0.80.91.20.91.01.0-1.0-1.00.8-1.00.1-1.1
Sum of active levers in priming session hrs 5-60.70.71.80.70.80.8-0.8-0.80.6-0.7-1.3-0.0
Progressive ratio4.85.56.3-1.9-2.4-2.52.42.4-2.42.52.42.3
Food seeking constrained by brief footshock0.00.00.10.10.10.2-0.2-0.20.10.20.2-0.1
Seeking ratio, punishment vs. effort4.35.26.21.92.32.5-2.4-2.42.3-2.3-2.4-2.1
Retroperitoneal fat weight0.41.43.0-0.8-1.1-1.11.11.1-1.31.21.71.0
Reaction time number correct0.20.20.70.80.2-0.20.10.1-0.80.80.5-0.2
Reaction time mean minus median0.70.92.8-1.7-0.50.1-0.1-0.11.6-1.6-0.1-0.3
Reaction time mean minus median AUC0.60.72.3-1.1-0.20.3-0.3-0.31.5-1.5-0.5-0.4
Reaction time num false alarms0.50.61.1-1.0-0.9-0.91.01.0-0.30.2-0.10.9
Reaction time num false alarms AUC0.81.12.1-1.2-1.1-1.11.21.3-0.60.5-0.21.4
Reaction time trials correct on left0.20.20.70.80.2-0.20.10.1-0.80.80.5-0.2
Reaction time trials on left0.20.20.60.70.1-0.20.10.1-0.80.80.4-0.1
Reaction time mean0.81.13.5-1.1-0.00.5-0.5-0.51.9-1.9-1.0-0.4
Reaction time mean AUC0.81.13.5-1.2-0.10.5-0.5-0.51.9-1.8-0.9-0.4
Median of all reaction times0.60.92.5-0.80.10.5-0.5-0.51.6-1.6-1.2-0.3
Reaction time omissions0.50.72.3-1.1-0.20.2-0.3-0.31.5-1.5-0.9-0.3
Reaction time false alarm rate0.60.92.1-1.4-1.0-0.80.91.0-0.0-0.1-0.61.4
Reaction time premature initiation rate1.31.72.2-1.0-1.3-1.41.31.3-1.41.50.71.5
Reaction time premature initiations1.52.13.7-0.7-1.3-1.51.41.4-1.91.91.01.4
Std. dev. reaction times0.71.03.4-1.8-0.7-0.10.10.11.5-1.5-0.50.2
Reaction time trials completed0.20.20.60.70.1-0.20.10.1-0.80.80.4-0.1
Reaction time trials AUC0.10.20.60.80.2-0.20.10.1-0.70.70.3-0.2
Run reversals in cocaine runway, females0.40.41.20.60.1-0.10.10.1-0.80.91.1-0.4
Run reversals in cocaine runway, males0.80.83.4-1.8-1.3-0.70.60.60.2-0.10.40.8
Latency to leave start box in cocaine runway0.10.10.9-0.1-0.2-0.20.10.1-0.2-0.0-0.51.0
Latency to leave start box in cocaine runway, F0.30.30.70.30.50.5-0.6-0.60.5-0.6-0.80.2
Latency to leave start box in cocaine runway, M1.21.11.6-0.6-1.1-1.31.21.2-1.31.01.01.0
Std. dev. time between licks in bursts1.11.34.9-1.5-0.7-0.30.30.31.1-1.0-2.21.2
Total sessions with >9 infusions0.10.10.4-0.1-0.10.0-0.2-0.2-0.50.50.10.6
Short access day 1 total inactive lever presses0.40.41.5-1.2-0.6-0.30.30.30.4-0.5-0.90.8
Short access day 10 total inactive lever presses0.10.20.6-0.5-0.2-0.20.30.30.4-0.3-0.80.0
Short access day 1 total infusions0.40.50.90.50.60.8-0.9-0.90.4-0.4-0.90.4
Short access day 10 total infusions0.10.10.4-0.1-0.2-0.1-0.0-0.0-0.60.7-0.00.6
Short access total infusions0.10.20.6-0.1-0.2-0.0-0.1-0.1-0.60.6-0.20.8
Short access day 1 locomotion3.43.64.71.62.02.2-2.1-2.11.8-1.8-2.0-1.3
Short access day 10 total locomotion0.60.61.8-1.0-0.5-0.20.20.30.5-0.5-1.41.3
Short access total locomotion0.30.31.30.00.30.5-0.6-0.60.4-0.4-1.10.5
One hour access (0.3 mA shock)0.60.71.50.80.91.1-1.2-1.20.5-0.5-0.2-0.7
Compulsive drug intake3.63.66.21.51.92.0-2.1-2.11.9-1.8-2.5-1.0
One hour access (shock baseline)0.60.72.2-0.9-0.9-0.70.60.7-0.80.71.50.3
Social response proportion0.30.31.5-0.7-0.4-0.30.10.10.1-0.1-0.71.2
Social responses0.30.42.1-0.5-0.5-0.60.50.5-0.30.4-0.51.5
Social time0.81.12.9-1.7-0.8-0.20.20.31.0-1.0-1.41.4
Soleus weight0.92.67.7-2.8-1.6-0.90.90.91.0-1.0-2.31.7
Bone: stiffness1.32.14.0-0.7-1.3-1.41.41.4-1.81.82.00.5
Tibialis anterior weight0.10.40.90.90.30.0-0.0-0.0-0.80.81.0-1.0
Time to tail flick, vehicle, before self-admin0.10.10.4-0.10.10.2-0.1-0.10.6-0.6-0.4-0.3
Time to tail flick, vehicle, after self-admin1.01.03.2-0.10.50.7-0.7-0.71.5-1.4-1.8-0.3
Time to tail flick, test, before self-admin0.10.10.40.2-0.0-0.20.20.2-0.50.60.4-0.0
Time to tail flick, test, after self-admin1.01.02.80.10.70.9-0.8-0.81.4-1.20.3-1.7
Delta time to tail flick, vehicle, before/after SA0.80.80.90.60.80.9-1.0-1.00.9-1.0-0.9-0.8
Delta time to tail flick, test, before/after SA1.21.12.80.71.01.0-1.0-1.01.2-1.20.2-1.7
Tibia length2.67.314.6-3.8-3.3-2.93.03.0-1.31.20.13.2
Ambulatory time before self-admin0.00.00.1-0.3-0.2-0.20.40.4-0.10.1-0.10.1
Ambulatory time after self-admin0.30.30.7-0.8-0.6-0.60.70.70.10.00.20.5
Bone: tissue strength4.44.35.0-1.5-2.1-2.22.22.2-2.22.22.01.9
Total heroin consumption0.00.10.30.10.10.0-0.1-0.10.2-0.10.5-0.4
Bone: trabecular number1.72.75.92.11.91.7-1.7-1.70.8-0.80.4-2.4
Bone: trabecular spacing4.15.48.8-2.6-2.6-2.52.52.6-1.71.70.63.0
Bone: trabecular thickness1.31.63.71.51.41.3-1.3-1.30.7-0.80.3-1.9
Bone: trabecular tissue density1.92.73.5-1.4-1.7-1.81.81.8-1.71.71.11.9
Water consumed over 24 hours0.10.10.3-0.3-0.1-0.10.10.10.2-0.2-0.50.5
Number of responses in last shaping day0.40.41.4-0.7-0.5-0.30.30.3-0.40.4-0.81.2