Best TWAS P=1.59285e-07 · Best GWAS P=6.987793e-06 conditioned to 0.8634357
| # | Tissue | Gene | Modality | RNA phenotype | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | Brain | Rasgrf1 | gene expression | ENSRNOG00000014025 | 0.14 | 0.04 | blup | 1301 | 0.04 | 0.00012 | -3.7 | 5.2 | 1.6e-07 | -0.84 | 0.25 | 0.66 | TRUE |
h2: Heritability estimate for the given transcriptomic model. PP3: Posterior probability of two distinct causal variants. PP4: Posterior probability of a single shared causal variant. joint: Whether the RNA phenotype is in the joint model.