Hub : Genes

G4

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose mRNA stability G4 0.03 0.02 4.4e-04 0.03 0.02 0.01 0.02 7.6e-04 3.8e-03 1.3e-02 2.8e-03
2 IL gene expression G4 0.14 0.09 4.0e-03 0.05 0.05 0.01 0.01 2.3e-02 2.6e-02 1.5e-01 2.3e-01
3 PL mRNA stability G4 0.07 0.05 4.3e-07 0.05 0.06 0.05 0.06 2.7e-06 1.7e-07 1.3e-06 3.1e-07
4 Adipose gene expression G4 0.09 0.05 6.3e-12 0.1 0.1 0.08 0.1 1.2e-10 4.7e-11 1.4e-09 8.9e-11
5 NAcc isoform ratio XM_039098956.1 0.05 0.03 4.0e-07 0.06 0.06 0.06 0.06 3.2e-07 1.9e-07 4.3e-07 3.8e-07
6 NAcc mRNA stability G4 0.06 0.03 5.2e-09 0.08 0.08 0.07 0.09 2.4e-09 1.4e-09 2.5e-08 3.1e-10
7 BLA gene expression G4 0.2 0.1 4.6e-09 0.07 0.12 0.12 0.12 9.2e-05 7.4e-07 4.2e-07 7.4e-07
8 pVTA isoform ratio NM_001003975.3 0.07 0.05 9.4e-03 0.03 0 -0.01 0 2.4e-02 2.0e-01 9.5e-01 2.8e-01
9 pVTA isoform ratio XM_039098956.1 0.07 0.05 8.8e-03 0.03 0.01 -0.01 0 1.8e-02 1.4e-01 9.3e-01 2.2e-01
10 Liver isoform ratio NM_001003975.3 0.07 0.04 4.0e-10 0.1 0.05 0.09 0.02 2.7e-11 7.0e-06 8.1e-10 1.6e-03
11 Liver isoform ratio XM_039098956.1 0.07 0.04 2.1e-10 0.1 0.05 0.09 0.02 1.6e-11 5.0e-06 6.1e-10 1.6e-03
12 NAcc isoform ratio NM_001003975.3 0.06 0.03 2.2e-07 0.06 0.06 0.06 0.06 1.2e-07 1.2e-07 4.0e-07 2.0e-07
13 Brain gene expression G4 0.09 0.06 6.0e-06 0.06 0.06 0.06 0.07 1.4e-06 5.4e-06 2.4e-06 7.6e-07
14 Brain isoform ratio NM_001003975.3 0.05 0.04 1.1e-04 0.05 0.03 0.01 0.04 2.4e-05 1.7e-03 1.3e-02 2.1e-04
15 Brain isoform ratio XM_039098956.1 0.06 0.04 7.7e-05 0.05 0.03 0.02 0.04 1.7e-05 1.3e-03 1.0e-02 1.7e-04
16 Brain mRNA stability G4 0.04 0.02 4.5e-04 0.01 0.03 0.02 0.02 1.4e-02 4.5e-04 6.6e-03 4.9e-03
17 OFC gene expression G4 0.19 0.1 8.8e-04 0.14 0.1 0.05 0.11 3.2e-04 2.4e-03 3.0e-02 1.3e-03
18 PL gene expression G4 0.25 0.17 1.9e-13 0.12 0.09 0.11 0.12 5.0e-13 3.0e-10 6.2e-12 1.3e-13
19 PL isoform ratio NM_001003975.3 0.11 0.06 1.5e-09 0.07 0.09 0.09 0.09 2.0e-08 1.8e-10 7.6e-10 1.1e-09
20 PL isoform ratio XM_039098956.1 0.12 0.07 6.6e-10 0.09 0.1 0.09 0.09 8.1e-10 8.3e-11 2.8e-10 4.3e-10
21 NAcc gene expression G4 0.08 0.04 8.8e-10 0.08 0.08 0.06 0.08 1.6e-09 1.3e-09 1.1e-07 1.9e-09
22 pVTA gene expression G4 0.14 0.08 4.4e-04 -0 0.04 0.03 0.01 5.2e-01 6.8e-03 2.6e-02 9.2e-02
23 BLA mRNA stability G4 0.06 0.04 3.6e-03 0.03 0.03 0.01 0.03 1.2e-02 1.3e-02 5.9e-02 1.5e-02
24 Liver gene expression G4 0.07 0.04 5.2e-05 0.04 0.05 0.06 0.06 9.5e-06 3.7e-06 1.7e-07 7.8e-07

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24
Bone: apparent density1.93.25.6-1.70.61.2-2.4-2.21.61.6-1.91.9-2.02.0-1.8-2.0-2.12.11.52.1-1.81.5-1.5-1.9-2.1-1.41.1
Area under the delay curve0.30.31.71.00.3-0.30.60.5-0.2-0.31.3-1.30.3-0.30.50.40.3-0.3-0.1-0.3-0.2-0.00.00.20.30.10.5
BMI with tail1.65.28.72.6-2.2-2.41.81.9-2.1-2.92.0-2.01.9-1.92.12.72.3-2.3-2.8-2.22.6-2.72.72.31.72.5-1.2
BMI without tail3.26.510.72.9-2.5-2.63.33.2-2.7-2.81.9-1.92.8-2.82.82.72.6-2.6-2.5-2.82.1-2.42.42.31.92.70.2
Body weight5.020.832.45.7-3.4-4.24.34.4-4.4-5.44.5-4.54.5-4.54.75.14.5-4.5-5.0-4.45.6-4.84.84.84.23.9-2.5
Weight adjusted by age5.56.28.62.1-1.0-2.32.72.8-2.7-2.52.3-2.32.9-2.92.72.52.7-2.7-2.6-2.62.8-2.32.32.82.62.4-1.7
Bone surface0.00.00.20.5-0.20.3-0.1-0.20.0-0.20.2-0.20.1-0.10.10.0-0.20.2-0.10.20.3-0.20.20.10.3-0.1-0.3
Bone volume0.00.10.30.3-0.50.1-0.5-0.50.1-0.0-0.00.0-0.30.3-0.2-0.4-0.40.40.00.4-0.00.0-0.0-0.3-0.4-0.10.2
Breakpoint value in progressive ratio session0.60.61.6-1.30.61.0-0.7-0.80.91.0-0.80.8-0.70.7-0.4-0.6-0.90.90.81.0-1.00.6-0.6-0.6-0.3-0.7-0.1
Number of licking bursts0.40.52.8-0.41.31.3-0.4-0.60.90.7-0.10.1-0.60.6-0.6-0.4-0.40.40.90.5-0.30.6-0.6-0.30.4-1.7-0.7
Context. condit. distance diff. score4.04.89.0-2.52.83.0-2.3-2.42.62.4-2.32.3-2.32.3-2.1-2.1-2.22.22.32.0-1.22.1-2.0-1.4-0.3-2.4-1.6
Locomotion velocity, session 10.40.51.7-0.31.30.7-0.2-0.30.70.8-0.50.5-0.60.6-0.6-1.1-0.50.50.90.4-0.61.1-1.1-0.7-0.3-0.40.3
Locomotion distance, session 11.41.82.6-0.80.91.1-1.6-1.61.41.1-1.01.0-1.51.5-1.6-1.5-1.51.51.31.4-1.41.4-1.4-1.5-1.5-1.50.8
Locomotion velocity, session 20.50.61.40.01.21.1-0.6-0.70.90.70.1-0.1-0.70.7-1.0-0.7-0.90.91.00.8-0.51.0-1.0-0.8-0.3-1.1-0.1
Locomotion distance, session 21.62.23.7-0.71.81.6-1.9-1.91.91.4-1.01.0-1.81.8-1.9-1.3-1.61.61.51.7-1.01.6-1.6-1.4-1.1-1.1-0.2
Locomotion velocity, session 30.10.11.30.1-0.6-0.70.40.5-0.3-0.2-0.00.00.2-0.20.10.10.4-0.4-0.2-0.4-0.3-0.00.0-0.1-0.50.11.2
Locomotion distance, session 32.72.94.6-1.51.51.4-1.8-1.71.91.8-1.61.6-2.02.0-2.2-1.9-1.61.61.71.8-1.61.9-1.9-1.9-1.7-1.20.9
Stereotopy head waving bouts, day 31.21.42.61.6-0.5-0.41.31.2-0.9-1.21.5-1.51.2-1.21.51.41.1-1.1-0.8-1.11.4-1.01.01.21.60.1-0.9
Stereotopy head waving duration, day 31.82.24.21.4-0.9-1.22.01.9-1.7-1.41.2-1.21.9-1.92.01.51.6-1.6-1.2-1.71.3-1.31.31.51.60.5-0.3
Locomotion velocity, session 76.06.610.0-2.42.62.5-3.2-3.12.92.6-2.52.5-3.03.0-3.1-2.6-2.72.72.42.7-2.02.5-2.5-2.4-2.0-1.7-0.0
Locomotion distance, session 77.19.011.7-2.52.82.8-3.4-3.33.33.2-2.62.6-3.43.4-3.3-3.4-3.23.23.13.3-2.83.2-3.2-3.2-2.8-2.00.7
Stereotopy head waving bouts, day 70.50.62.91.7-0.4-0.51.00.9-0.5-0.61.7-1.70.5-0.50.60.20.4-0.4-0.1-0.50.30.1-0.1-0.1-0.1-0.41.1
Stereotopy head waving duration, day 70.91.14.02.0-0.7-0.91.31.2-0.9-1.11.9-1.91.0-1.01.00.70.9-0.9-0.6-0.90.9-0.50.50.50.40.00.6
Locomotion velocity, session 80.70.95.10.22.31.8-0.3-0.51.10.80.3-0.3-0.60.6-0.6-0.5-0.40.41.10.40.51.0-0.9-0.11.1-1.0-1.7
Locomotion distance, session 84.76.912.3-2.13.43.5-3.2-3.33.32.6-2.12.1-3.03.0-2.9-2.4-2.72.72.62.6-1.22.5-2.5-1.9-0.8-2.5-1.8
Degree of sensitization distance0.20.21.2-0.50.70.8-0.3-0.40.40.4-0.30.3-0.20.2-0.1-0.2-0.40.40.40.2-0.00.2-0.20.00.5-0.3-1.1
Degree of sensitization stereotypy0.40.41.91.30.00.00.30.20.20.01.4-1.4-0.20.2-0.1-0.5-0.20.20.50.2-0.30.7-0.7-0.7-0.7-0.61.3
Conditioned locomotion0.80.92.51.0-0.6-0.30.50.5-0.6-1.10.4-0.40.8-0.81.01.21.0-1.0-0.9-0.81.5-1.01.01.21.40.5-1.6
Cocaine response after cond. corrected0.80.92.4-0.80.71.3-1.6-1.51.00.6-0.80.8-0.90.9-1.1-0.3-1.31.30.61.1-0.40.4-0.4-0.5-0.1-1.1-1.2
Cocaine response after cond. not corrected0.20.21.70.40.20.50.0-0.1-0.1-0.40.5-0.50.3-0.30.20.7-0.00.0-0.2-0.10.6-0.50.50.61.0-0.1-1.3
Cocaine response before conditioning4.95.910.82.7-1.5-2.03.33.1-2.3-2.22.9-2.92.6-2.62.72.12.8-2.8-1.9-2.62.2-1.91.92.22.22.6-0.1
Saline control response3.14.19.31.2-3.1-2.82.02.2-2.9-2.10.7-0.72.5-2.52.31.82.1-2.1-2.2-1.91.1-2.22.11.50.42.21.3
Bone: connectivity density1.72.65.9-2.20.71.4-2.2-2.11.31.6-2.42.4-1.51.5-1.5-1.6-1.91.91.21.8-1.41.0-1.0-1.3-1.3-1.30.1
Bone: cortical apparent density0.60.83.90.5-2.0-1.50.50.7-1.0-1.10.4-0.40.7-0.71.00.90.7-0.7-1.2-0.70.4-1.21.10.6-0.20.90.5
Bone: cortical area0.50.84.02.0-0.8-0.50.70.6-0.4-1.11.7-1.70.4-0.40.60.80.6-0.6-0.7-0.71.2-0.70.70.60.60.5-0.3
Bone: cortical porosity0.40.53.30.8-0.0-0.81.21.1-0.4-0.00.9-0.90.4-0.40.5-0.30.6-0.60.1-0.5-0.50.4-0.4-0.3-0.50.21.8
Bone: cortical porosity0.40.51.71.00.4-0.41.31.1-0.4-0.01.1-1.10.6-0.60.6-0.20.6-0.60.2-0.6-0.10.4-0.3-0.00.1-0.11.2
Bone: cortical thickness0.61.04.52.1-1.8-1.30.40.5-0.6-1.31.9-1.90.2-0.20.50.60.3-0.3-0.9-0.60.5-0.70.60.0-0.70.91.1
Bone: cortical thickness0.40.53.10.5-1.8-1.20.20.3-0.7-0.90.4-0.40.3-0.30.30.80.3-0.3-0.9-0.60.0-0.90.80.1-0.60.70.9
Bone: cortical tissue density0.70.93.70.4-1.9-1.50.70.8-1.1-1.20.3-0.30.8-0.81.11.00.8-0.8-1.2-0.80.5-1.21.20.7-0.00.90.4
Condit. Reinf. active minus inactive responses0.91.01.9-1.01.10.6-0.5-0.51.01.3-1.41.4-1.01.0-1.0-1.1-0.80.81.10.7-1.21.2-1.2-1.1-1.0-0.41.3
Condit. Reinf. active-inactive response ratio0.10.11.50.0-0.3-0.60.50.5-0.10.0-0.10.1-0.00.00.00.10.1-0.1-0.1-0.2-0.4-0.10.1-0.2-0.50.41.2
Condit. Reinf. active responses1.31.63.6-1.41.10.8-1.1-1.11.31.5-1.91.9-1.41.4-1.4-1.4-1.11.11.21.1-1.31.3-1.3-1.3-1.4-0.21.0
Condit. Reinf. inactive responses2.52.94.9-1.81.01.2-2.1-1.91.61.7-2.22.2-1.81.8-1.9-1.9-1.71.71.51.8-1.61.6-1.7-1.8-2.0-0.30.7
Incentive salience index mean2.42.95.6-1.22.42.0-1.6-1.72.11.9-1.81.8-2.02.0-1.9-1.7-1.61.61.91.6-1.11.8-1.8-1.5-0.8-1.3-0.0
Condit. Reinf. lever presses3.44.58.3-1.72.82.9-2.4-2.52.62.2-2.22.2-2.32.3-2.3-1.9-2.22.22.22.2-1.02.0-2.0-1.5-0.5-1.7-1.3
Condit. Reinf. active minus inactive responses1.21.52.91.4-0.9-1.11.71.6-1.1-1.21.4-1.41.2-1.21.41.11.4-1.4-1.0-1.21.0-0.90.91.11.01.50.2
Condit. Reinf. active-inactive response ratio1.92.04.01.9-0.7-1.01.91.8-1.2-1.42.0-2.01.5-1.51.61.21.5-1.5-1.1-1.51.4-1.01.01.41.51.0-0.4
Condit. Reinf. active responses0.30.41.5-0.0-0.7-0.70.90.9-0.6-0.4-0.00.00.6-0.60.70.40.8-0.8-0.5-0.60.2-0.40.40.50.31.20.5
Condit. Reinf. inactive responses0.30.42.7-1.5-0.5-0.3-0.2-0.10.00.4-1.61.6-0.20.2-0.10.00.0-0.0-0.00.1-0.6-0.20.1-0.2-0.60.70.6
Condit. Reinf. lever presses0.20.21.1-0.70.0-0.20.20.20.10.5-0.80.8-0.20.2-0.2-0.6-0.10.10.30.0-0.60.4-0.4-0.4-0.61.10.9
Condit. Reinf. lever reinforcers received0.20.21.2-0.1-0.4-0.50.80.8-0.4-0.2-0.10.10.4-0.40.60.20.6-0.6-0.2-0.5-0.0-0.20.20.30.21.10.6
Conditioned reinforcement - actives0.30.31.30.6-0.0-0.50.60.6-0.6-0.60.6-0.60.6-0.60.30.40.6-0.6-0.6-0.30.4-0.40.40.60.61.1-0.5
Conditioned reinforcement - inactives0.40.51.31.2-0.5-1.10.80.9-0.9-0.70.7-0.70.7-0.70.70.30.7-0.7-0.7-0.60.2-0.40.40.3-0.10.90.8
Conditioned locomotion0.10.10.50.20.7-0.20.30.4-0.4-0.00.0-0.00.4-0.40.3-0.10.4-0.4-0.3-0.20.1-0.10.10.50.50.5-0.4
Patch foraging indifference point 0 sec1.72.76.20.6-2.1-2.51.92.0-2.4-1.60.4-0.42.1-2.11.61.71.6-1.6-1.9-1.70.6-1.81.71.40.41.81.0
Patch foraging indifference point AUC0.40.53.61.9-0.3-0.40.90.7-0.5-0.81.3-1.30.6-0.60.60.50.4-0.4-0.2-0.50.5-0.10.10.10.2-0.40.6
Delay disc. indifference point, 0s delay0.20.21.60.41.30.7-0.1-0.20.30.20.6-0.6-0.00.0-0.00.1-0.10.10.30.10.30.2-0.20.10.6-0.3-1.0
Delay disc. indifference point, 16s delay0.20.21.30.6-0.2-0.40.20.2-0.0-0.00.7-0.7-0.10.10.1-0.0-0.00.0-0.0-0.4-0.80.1-0.2-0.3-0.50.31.2
Delay disc. indifference point, 2s delay1.01.14.11.60.5-0.51.41.3-0.7-0.82.0-2.01.0-1.01.20.91.0-1.0-0.5-0.40.8-0.40.40.81.20.3-0.5
Delay disc. indifference point, 24s delay0.70.61.90.4-0.4-1.01.21.2-0.8-0.30.8-0.80.9-0.90.90.60.9-0.9-0.6-1.4-0.3-0.40.40.50.31.10.8
Delay disc. indifference point, 4s delay1.21.32.41.5-0.4-0.91.51.4-1.1-1.11.4-1.41.3-1.31.31.31.3-1.3-0.9-1.00.9-1.01.01.11.20.9-0.0
Delay disc. indifference point, 8s delay0.10.10.60.20.80.2-0.1-0.20.40.40.4-0.4-0.30.3-0.1-0.1-0.30.30.40.3-0.70.4-0.4-0.4-0.2-0.30.6
Indifference point function ln k0.20.31.0-0.71.00.9-0.3-0.40.70.8-0.40.4-0.50.5-0.4-0.5-0.50.50.70.5-0.50.7-0.6-0.40.1-0.4-0.3
Indifference point function log k0.20.31.0-0.71.00.9-0.3-0.40.70.8-0.40.4-0.50.5-0.4-0.5-0.50.50.70.5-0.50.7-0.6-0.40.1-0.4-0.3
Patch foraging total patch changes 0 sec1.82.96.60.8-2.2-2.61.92.0-2.5-1.60.5-0.52.1-2.11.71.71.6-1.6-1.9-1.80.5-1.81.71.30.32.01.2
Patch foraging total patch changes 12 sec1.21.63.60.9-1.8-1.81.31.4-1.9-1.21.0-1.01.6-1.61.11.11.1-1.1-1.2-1.20.3-1.21.20.7-0.01.31.2
Patch foraging total patch changes 18 sec0.50.74.10.2-2.0-1.50.10.3-1.0-0.8-0.30.30.5-0.50.20.70.2-0.2-0.9-0.2-0.4-0.90.90.0-1.00.51.6
Patch foraging total patch changes 24 sec0.40.53.0-0.7-0.6-0.7-0.6-0.5-0.00.3-0.50.5-0.40.4-0.7-0.6-0.60.60.10.3-1.20.3-0.3-0.9-1.70.21.7
Patch foraging total patch changes 6 sec1.11.74.60.8-1.8-2.11.41.5-1.9-1.30.2-0.21.6-1.61.21.21.2-1.2-1.5-1.30.2-1.31.30.9-0.11.11.3
Patch foraging time to switch 0 sec0.20.31.0-0.6-1.0-0.6-0.5-0.3-0.3-0.6-0.40.4-0.00.00.00.70.2-0.2-0.9-0.10.2-1.00.90.50.10.8-0.6
Patch foraging water rate 0 sec0.20.30.80.80.0-0.40.60.5-0.5-0.40.9-0.90.6-0.60.70.50.4-0.4-0.4-0.40.5-0.30.30.50.5-0.1-0.2
Patch foraging water rate 12 sec0.30.51.2-0.4-0.10.2-0.8-0.70.70.5-0.30.3-0.80.8-0.5-0.7-0.80.80.50.8-0.90.5-0.6-0.9-1.1-1.00.9
Patch foraging water rate 18 sec0.10.10.40.3-0.4-0.60.40.4-0.4-0.2-0.10.10.3-0.30.70.30.5-0.5-0.4-0.30.4-0.40.40.30.1-0.20.2
Patch foraging water rate 24 sec0.20.32.21.5-0.9-0.40.10.1-0.1-0.61.2-1.20.0-0.00.50.1-0.10.1-0.30.10.4-0.20.2-0.1-0.20.40.3
Patch foraging water rate 6 sec0.10.11.3-0.1-0.00.0-0.3-0.30.20.10.0-0.0-0.30.3-0.2-0.1-0.40.40.20.3-0.40.2-0.2-0.4-0.5-1.10.5
Seeking ratio, delayed vs. immediate footshock0.81.03.40.7-1.8-1.01.31.2-1.1-0.90.6-0.61.0-1.01.11.30.9-0.9-0.8-0.70.1-1.11.10.60.41.11.0
Distance traveled before self-admin0.20.32.1-0.0-0.20.4-0.4-0.40.2-0.5-0.30.3-0.10.1-0.20.60.1-0.1-0.30.20.9-0.60.60.50.8-0.1-1.5
Distance traveled after self-admin1.71.83.30.5-1.6-1.01.51.5-1.4-1.30.6-0.61.5-1.51.51.61.5-1.5-1.3-1.81.4-1.61.61.51.40.7-0.5
Extensor digitorum longus weight0.10.42.40.50.40.20.40.4-0.4-0.40.1-0.10.6-0.60.40.40.5-0.5-0.4-0.61.1-0.50.50.91.30.6-1.6
Bone: elastic displacement0.20.32.40.20.1-0.50.10.20.00.10.3-0.3-0.20.2-0.2-0.6-0.20.20.20.1-0.50.6-0.6-0.6-1.0-0.61.5
Bone: elastic work0.40.52.71.6-0.2-0.60.50.5-0.4-0.81.5-1.50.3-0.30.40.30.3-0.3-0.4-0.60.7-0.20.20.20.10.00.4
Bone: endosteal estimation3.57.715.62.4-1.0-1.43.33.1-2.4-2.52.2-2.23.0-3.03.02.93.2-3.2-2.3-2.93.5-2.52.63.33.92.2-2.6
Bone: endosteal perimeter0.71.46.70.50.70.51.20.9-0.5-0.50.4-0.41.1-1.11.01.21.2-1.2-0.5-1.01.8-0.91.01.62.60.5-2.5
Epididymis fat weight1.63.813.51.2-3.7-3.41.11.5-2.1-2.31.4-1.41.3-1.31.51.71.4-1.4-2.5-1.30.0-2.22.10.9-0.93.51.9
Delta time in closed arm before/after self-admin1.11.12.00.4-0.5-0.60.90.9-1.0-0.90.8-0.81.1-1.11.31.21.1-1.1-1.1-1.01.2-1.21.21.41.40.4-1.3
Delta time in open arm before/after self-admin0.10.11.10.1-0.1-0.50.10.2-0.10.1-0.40.4-0.20.2-0.6-0.6-0.00.00.0-0.1-0.20.3-0.3-0.4-0.80.01.0
Diff in mean of infusions in LGA sessions4.14.67.6-2.32.12.3-2.6-2.62.32.1-2.12.1-2.32.3-2.0-1.8-2.52.52.12.8-2.11.9-1.9-2.0-1.5-1.50.0
Delay discount exponential model param0.30.31.8-1.0-0.20.4-0.8-0.70.30.3-1.31.3-0.40.4-0.6-0.5-0.50.50.20.40.20.1-0.1-0.2-0.3-0.2-0.6
Extinction: sum of active levers before priming0.30.30.9-0.80.90.7-0.4-0.40.60.7-0.40.4-0.40.4-0.4-0.4-0.50.50.60.3-0.80.5-0.5-0.30.0-1.0-0.3
Active lever presses in extinction session 60.00.00.3-0.40.2-0.50.10.2-0.3-0.00.1-0.10.2-0.20.3-0.20.1-0.1-0.3-0.2-0.1-0.10.10.2-0.1-0.10.1
Bone: final force2.64.310.73.3-2.4-2.01.41.5-1.9-2.72.9-2.91.8-1.81.82.31.5-1.5-2.2-1.82.3-2.12.11.71.22.0-0.7
Bone: final moment2.43.89.73.1-2.2-1.91.51.6-1.9-2.52.6-2.61.8-1.81.72.01.5-1.5-2.1-1.82.2-2.01.91.61.11.9-0.6
Food consumed during 24 hour testing period0.60.72.71.1-0.10.00.30.2-0.4-0.90.5-0.50.6-0.60.61.10.6-0.6-0.7-0.71.6-0.80.91.01.30.3-1.7
Glucose1.11.69.0-0.62.82.2-0.4-0.61.51.1-0.80.8-0.80.8-0.3-0.7-0.40.41.10.30.70.9-0.90.31.7-1.6-3.0
Heart weight0.91.22.90.4-0.3-0.91.71.6-1.1-0.71.4-1.41.3-1.31.51.01.3-1.3-0.8-1.00.4-0.80.81.01.11.30.2
Delay discount hyperbolic model param0.40.42.2-1.1-0.20.4-1.0-0.80.40.4-1.51.5-0.50.5-0.7-0.5-0.60.60.20.50.10.1-0.1-0.3-0.4-0.2-0.6
Intermittent access intake day 1-15 change0.30.32.70.8-0.9-0.30.10.0-0.1-0.2-0.00.0-0.10.1-0.3-0.2-0.20.20.10.3-0.40.2-0.2-0.6-0.9-0.41.6
Intermittent access intake escalation0.20.21.00.5-0.40.2-0.3-0.40.20.1-0.20.2-0.30.3-0.6-0.2-0.50.50.40.5-0.20.3-0.3-0.5-0.6-1.00.9
Intermittent access intake escalation 21.11.14.20.01.11.5-0.9-1.11.20.9-0.50.5-1.01.0-1.1-1.0-1.11.11.31.1-0.21.2-1.2-1.0-0.4-2.0-0.0
Intermitt. access day 1 inactive lever presses0.70.72.50.5-0.40.10.60.5-0.4-0.70.8-0.80.7-0.70.81.20.8-0.8-0.6-0.71.0-0.91.01.11.60.1-1.5
Intermitt. access day 15 inactive lever presses1.71.94.12.0-1.1-1.31.51.5-1.3-1.61.7-1.71.3-1.31.51.31.5-1.5-1.3-1.51.4-1.11.21.10.91.0-0.0
Intermitt. access escalation Index2.11.83.6-1.91.31.7-1.5-1.61.41.4-1.11.1-1.31.3-1.5-0.9-1.41.41.31.5-1.61.1-1.0-1.1-0.6-1.7-0.1
Intermittent access day 1 total infusions0.80.92.3-0.91.50.6-0.9-0.80.91.1-0.80.8-0.90.9-0.9-1.4-0.90.90.91.1-1.11.2-1.2-1.0-1.0-0.30.4
Intermittent access day 15 total infusions0.40.50.8-0.40.40.3-0.7-0.60.50.6-0.70.7-0.60.6-0.9-0.9-0.70.70.60.9-0.80.7-0.7-0.8-0.9-0.50.8
Intermittent access terminal intake (last 3 days)0.00.00.20.00.4-0.20.20.2-0.10.10.0-0.00.0-0.0-0.1-0.40.1-0.10.1-0.0-0.30.3-0.3-0.2-0.30.30.4
Intermittent access total infusions0.10.10.5-0.10.6-0.2-0.10.00.00.3-0.30.3-0.10.1-0.3-0.7-0.10.10.10.3-0.50.5-0.5-0.3-0.50.30.5
Intermittent access day 1 locomotion0.10.10.5-0.50.0-0.20.00.1-0.20.2-0.70.70.2-0.20.3-0.10.3-0.3-0.20.0-0.0-0.10.10.30.20.4-0.2
Intermittent access day 15 total locomotion0.40.51.00.9-0.9-0.70.60.6-0.7-0.80.1-0.10.7-0.70.90.70.7-0.7-0.7-0.61.0-0.80.80.70.60.2-0.1
Intermittent access total locomotion0.10.20.70.7-0.5-0.60.20.3-0.4-0.5-0.20.20.3-0.30.40.20.4-0.4-0.5-0.10.8-0.40.40.40.10.4-0.0
Intermittent access standard deviation2.32.53.81.5-1.9-2.01.61.7-1.8-1.81.4-1.41.7-1.71.61.61.6-1.6-1.7-1.61.0-1.71.61.40.81.90.4
Left kidney weight2.98.114.73.8-2.1-2.62.62.7-2.8-3.33.6-3.62.8-2.82.82.92.7-2.7-3.0-2.63.2-2.72.72.72.32.4-1.1
Right kidney weight2.57.212.43.5-2.1-2.32.62.6-2.8-3.12.6-2.62.9-2.92.62.82.5-2.5-2.8-2.63.4-2.72.72.72.42.0-1.4
Cocaine induced anxiety1.51.84.3-1.50.91.6-1.7-1.71.51.1-2.12.1-1.41.4-1.5-0.7-1.41.41.11.2-0.40.7-0.7-0.9-0.5-1.7-0.6
Post-drug Anxiety0.20.21.2-0.60.30.6-0.3-0.30.30.0-0.80.8-0.20.2-0.40.3-0.10.10.0-0.20.4-0.30.30.30.6-0.5-1.1
Baseline Anxiety1.11.12.30.2-0.4-1.01.51.5-1.2-0.71.0-1.01.3-1.31.21.01.3-1.3-0.9-1.50.4-0.90.91.11.01.3-0.4
Tail length2.68.015.94.0-0.9-1.73.93.5-2.8-2.73.0-3.03.5-3.53.52.62.8-2.8-2.0-2.93.3-2.02.02.83.31.3-1.1
Length with tail2.48.718.94.3-0.9-2.03.23.0-2.7-3.13.8-3.83.1-3.13.33.02.8-2.8-2.6-2.53.9-2.42.43.03.21.5-1.8
Length without tail1.94.19.52.9-0.6-1.31.21.2-1.6-2.43.1-3.11.7-1.71.82.11.7-1.7-2.1-1.33.1-1.91.92.12.21.1-2.3
Times rat made contact with spout1.51.86.4-1.4-0.10.1-0.9-0.80.91.3-1.71.7-1.21.2-1.1-1.2-1.01.01.10.9-1.91.2-1.2-1.7-2.2-1.02.5
Lifetime Intake0.10.10.6-0.10.8-0.20.10.2-0.10.2-0.20.20.1-0.1-0.1-0.50.1-0.10.00.2-0.30.3-0.4-0.1-0.20.40.1
Liver weight, left0.91.53.10.9-1.1-0.91.21.2-1.1-1.30.2-0.21.2-1.21.41.41.3-1.3-1.3-1.21.8-1.41.41.51.50.8-1.2
Liver weight, right1.22.07.12.7-0.10.01.51.2-0.8-1.32.3-2.31.3-1.31.41.21.0-1.0-0.6-1.22.2-0.70.81.32.1-0.2-1.5
Locomotor activity1.32.13.71.5-0.9-0.91.91.8-1.4-1.41.1-1.11.6-1.61.31.61.7-1.7-1.0-1.91.9-1.11.21.31.51.5-0.4
Locomotor testing distance0.71.22.20.7-0.7-0.81.41.3-1.2-1.00.4-0.41.3-1.30.81.31.2-1.2-0.9-1.51.2-1.01.01.21.21.5-0.6
Locomotor testing rearing1.21.83.41.2-0.8-0.91.31.2-1.4-1.41.0-1.01.6-1.61.21.51.4-1.4-1.3-1.61.8-1.31.31.51.61.2-1.2
Locomotion in novel chamber0.10.10.50.7-0.3-0.30.30.3-0.3-0.50.6-0.60.3-0.30.20.20.3-0.3-0.2-0.30.3-0.10.10.10.00.00.2
Locomotion in novel chamber post-restriction1.01.21.90.6-1.2-1.31.01.1-1.4-1.10.9-0.91.3-1.31.21.21.2-1.2-1.3-0.40.3-1.31.21.20.81.40.1
Fecal boli incidents, locomotor time 10.10.10.5-0.70.1-0.3-0.10.1-0.20.1-0.70.70.0-0.0-0.1-0.30.1-0.1-0.20.4-0.4-0.0-0.00.1-0.10.4-0.0
Change in fecal boli incidents, locomotor task0.60.62.40.70.30.50.50.3-0.1-0.41.5-1.50.5-0.50.80.80.4-0.4-0.1-0.60.4-0.30.30.71.3-0.9-1.3
Time >=10cm from walls, locomotor time 12.32.35.31.1-0.8-0.61.01.0-1.1-1.61.2-1.21.3-1.31.52.01.5-1.5-1.6-1.32.1-1.81.92.02.31.0-2.3
Bouts of movement, locomotor time 11.41.53.1-1.60.81.3-1.2-1.31.51.3-1.81.8-1.51.5-1.3-1.0-1.31.31.30.8-0.61.0-1.0-1.1-0.8-0.70.0
Total resting periods, locomotor time 10.91.02.0-1.30.81.2-1.0-1.11.31.1-1.41.4-1.21.2-1.1-0.9-1.01.01.10.6-0.40.9-0.9-0.9-0.5-0.7-0.1
Rest time, locomotor task time 10.10.10.90.10.1-0.10.50.4-0.2-0.2-0.20.20.3-0.30.4-0.10.3-0.3-0.0-0.90.90.0-0.00.20.3-0.4-0.1
Distance moved, locomotor task time 10.30.30.70.8-0.8-0.60.30.4-0.5-0.60.9-0.90.5-0.50.50.80.4-0.4-0.6-0.60.4-0.60.60.40.30.8-0.1
Vertical activity count, locomotor time 10.40.41.20.6-1.1-0.80.30.3-0.7-0.80.6-0.60.6-0.60.51.10.3-0.3-0.8-0.20.1-0.90.90.50.20.50.2
Time >=10cm from walls, locomotor time 21.92.04.70.5-0.1-0.81.31.3-1.3-1.21.0-1.01.6-1.61.21.81.6-1.6-1.4-1.51.1-1.61.62.02.21.0-1.7
Bouts of movement, locomotor time 20.10.10.60.8-0.3-0.20.70.6-0.2-0.30.5-0.50.3-0.30.20.20.3-0.3-0.0-0.00.6-0.10.10.00.1-0.00.6
Total resting periods, locomotor time 20.10.10.50.50.00.10.70.50.0-0.10.3-0.30.2-0.20.10.10.2-0.20.2-0.10.40.1-0.1-0.00.2-0.40.6
Rest time, locomotor task time 20.50.63.4-0.30.81.3-0.6-0.70.70.2-0.60.6-0.50.5-0.4-0.1-0.40.40.50.11.20.2-0.20.10.8-1.8-1.7
Distance moved, locomotor task time 20.50.62.80.6-0.6-1.20.40.6-0.9-0.70.9-0.90.7-0.70.40.70.6-0.6-1.0-1.20.4-0.70.70.60.11.7-0.1
Vertical activity count, locomotor time 20.60.62.70.0-0.6-1.10.60.7-1.0-0.60.3-0.30.9-0.90.90.90.7-0.7-1.0-0.90.1-0.90.90.80.41.7-0.2
Light reinforcement 10.20.31.00.3-1.0-0.2-0.3-0.2-0.3-0.80.5-0.50.2-0.20.11.00.1-0.1-0.7-0.30.4-0.90.90.50.3-0.5-0.5
Light reinforcement 20.30.42.20.9-0.3-0.0-0.1-0.0-0.2-0.80.5-0.50.2-0.20.10.90.5-0.5-0.7-0.61.5-0.80.70.70.8-0.1-1.2
Bone: marrow area3.98.416.22.4-1.2-1.53.43.2-2.6-2.62.2-2.23.2-3.23.23.03.4-3.4-2.5-3.13.6-2.72.83.54.02.4-2.6
Bone: maximum diameter0.30.52.71.10.91.00.20.00.5-0.10.9-0.9-0.00.00.00.20.1-0.10.3-0.11.20.1-0.10.51.3-0.7-1.6
Bone: maximum force1.93.310.03.2-1.9-1.71.41.4-1.6-2.42.6-2.61.5-1.51.61.81.4-1.4-1.9-1.62.2-1.81.71.51.11.7-0.6
Bone: maximum moment1.83.19.13.0-1.7-1.71.51.5-1.5-2.22.4-2.41.5-1.51.61.61.4-1.4-1.8-1.72.2-1.61.61.41.11.6-0.5
Mean time between licks in bursts0.30.52.3-0.01.51.4-0.2-0.40.80.6-0.10.1-0.30.3-0.4-0.5-0.50.50.80.30.40.7-0.60.00.9-0.5-1.5
Mean num. licks in bursts0.50.53.8-0.3-1.4-1.30.10.3-0.5-0.2-0.80.80.0-0.00.1-0.10.1-0.1-0.4-0.2-0.6-0.10.1-0.5-1.41.02.0
Cd content in liver0.10.10.40.6-0.5-0.5-0.6-0.3-0.3-0.50.2-0.20.0-0.0-0.0-0.0-0.00.0-0.5-0.10.5-0.30.20.1-0.40.1-0.2
Co content in liver2.22.63.81.1-1.8-1.91.41.6-1.8-1.81.5-1.51.7-1.71.61.71.7-1.7-1.9-1.60.9-1.91.81.50.91.9-0.0
Cu content in liver3.23.87.2-2.01.01.0-2.0-1.91.91.9-1.61.6-2.22.2-2.0-1.9-2.02.01.82.0-2.51.9-1.9-2.4-2.7-1.42.0
Fe content in liver0.81.02.50.7-1.2-1.60.80.9-1.6-1.10.8-0.81.3-1.31.40.50.8-0.8-1.2-0.70.5-1.00.90.7-0.11.10.7
K content in liver0.90.91.8-0.51.11.4-1.0-1.11.40.9-0.10.1-1.21.2-0.9-1.0-1.11.11.11.0-0.61.0-1.0-0.8-0.3-1.2-0.4
Mg content in liver2.82.96.8-1.52.52.6-1.3-1.52.12.0-1.21.2-1.71.7-1.6-1.7-1.71.72.01.3-1.11.8-1.8-1.10.1-2.3-1.0
Mn content in liver0.80.95.0-0.82.01.9-0.2-0.51.10.9-0.60.6-0.60.6-0.6-0.1-0.30.30.90.20.50.5-0.50.31.6-0.9-2.2
Na content in liver0.60.61.00.20.40.9-0.9-0.91.00.60.2-0.2-1.01.0-0.7-0.7-1.01.00.90.9-0.70.8-0.8-0.9-0.7-1.00.2
Rb content in liver0.40.41.4-1.20.60.8-0.9-0.90.40.6-1.01.0-0.30.3-0.4-0.5-0.60.60.30.4-0.20.2-0.20.00.2-1.0-1.0
Se content in liver1.41.76.2-0.72.52.2-0.4-0.71.61.7-0.60.6-1.21.2-1.3-1.3-1.01.02.00.8-0.81.9-1.8-1.00.1-1.6-0.2
Sr content in liver0.70.61.90.8-0.1-0.40.60.7-0.5-0.70.7-0.70.6-0.60.80.50.6-0.6-0.8-0.71.4-0.70.71.01.20.7-1.4
Zn content in liver0.10.11.3-0.00.70.3-0.0-0.00.1-0.00.5-0.50.0-0.00.10.10.1-0.1-0.1-0.10.3-0.10.10.50.80.1-1.1
Bone: minimum diameter0.81.45.01.20.30.11.11.0-0.5-0.91.0-1.00.9-0.91.01.21.2-1.2-0.7-1.11.9-1.01.01.52.20.9-2.2
Time in familiar zone, hab. session 12.52.36.2-2.00.00.1-1.3-1.10.91.5-1.91.9-1.41.4-1.4-1.7-1.31.31.11.4-2.21.3-1.3-1.8-2.5-0.12.3
Time in novel zone, hab. session 12.52.55.61.4-0.4-0.61.71.5-1.4-1.51.4-1.41.8-1.81.71.81.6-1.6-1.4-1.72.0-1.51.62.02.40.2-1.7
Total zone transitions, hab. session 10.50.71.1-1.00.51.0-1.0-1.00.80.9-1.01.0-0.70.7-0.9-0.8-0.90.90.90.9-0.90.8-0.8-0.8-0.6-0.8-0.1
Total locomotion distance, hab. session 10.60.81.3-0.90.61.0-1.2-1.10.90.9-1.01.0-0.90.9-1.0-0.9-1.01.00.91.0-0.90.9-0.9-0.8-0.6-0.5-0.2
Locomotion velocity, hab. session 10.30.50.7-0.60.40.8-0.8-0.80.70.7-0.60.6-0.70.7-0.7-0.7-0.70.70.70.8-0.80.7-0.7-0.7-0.5-0.2-0.1
Time in familiar zone, hab. session 20.20.21.1-0.6-1.0-0.3-0.2-0.20.10.1-0.50.5-0.40.4-0.20.0-0.20.20.00.3-0.7-0.10.1-0.4-0.80.80.9
Time in novel zone, hab. session 20.40.40.70.60.2-0.60.80.8-0.8-0.50.4-0.40.8-0.80.80.30.7-0.7-0.5-0.70.7-0.30.30.60.6-0.70.0
Total zone transitions, hab. session 20.20.31.0-0.1-0.00.7-1.0-0.90.60.2-0.10.1-0.60.6-0.7-0.2-0.70.70.40.8-0.30.3-0.3-0.4-0.3-0.6-0.4
Total locomotion distance, hab. session 21.41.94.1-1.30.71.6-2.0-2.01.51.2-1.41.4-1.51.5-1.6-1.1-1.51.51.21.6-1.11.0-1.0-1.2-0.9-1.5-0.4
Locomotion velocity, hab. session 21.92.65.1-1.41.12.0-2.3-2.21.81.5-1.41.4-1.81.8-1.9-1.4-1.81.81.51.9-1.31.4-1.4-1.4-1.0-1.7-0.4
Novel to familiar place preference ratio0.20.21.60.00.40.3-0.3-0.30.30.40.1-0.1-0.30.3-0.2-0.5-0.60.60.50.4-0.70.6-0.6-0.6-0.5-1.30.7
Novelty place preference0.20.21.30.30.30.20.0-0.00.00.30.3-0.3-0.00.0-0.0-0.4-0.40.40.40.1-0.50.5-0.5-0.4-0.3-1.10.7
Time in novel zone, NPP test0.10.10.90.40.2-0.00.30.2-0.20.10.4-0.40.2-0.20.2-0.2-0.10.10.2-0.1-0.30.3-0.3-0.2-0.2-1.00.7
Total zone transitions, NPP test1.62.33.5-1.41.41.6-1.9-1.81.61.5-1.61.6-1.61.6-1.7-1.6-1.51.51.41.7-1.11.4-1.5-1.3-1.0-1.6-0.3
Total locomotion distance, NPP test1.62.14.4-1.41.41.4-2.1-2.01.41.4-1.61.6-1.51.5-1.8-1.5-1.51.51.21.6-1.01.3-1.3-1.2-1.0-1.5-0.6
Locomotion velocity, NPP test2.53.56.9-1.91.71.9-2.6-2.51.91.8-1.91.9-2.02.0-2.3-1.8-2.02.01.62.1-1.41.6-1.7-1.6-1.3-2.0-0.7
Intraocular pressure0.60.83.0-1.3-0.20.1-1.1-0.90.40.7-1.71.7-0.70.7-0.9-0.7-0.90.90.31.2-0.80.3-0.3-0.7-1.10.10.7
Delta distance traveled before/after self-admin1.61.84.11.2-1.3-1.62.02.0-1.6-1.01.3-1.31.6-1.61.60.81.4-1.4-1.0-1.90.5-0.80.80.80.50.91.3
Delta ambulatory time before/after self-admin0.91.02.40.9-1.0-1.01.51.4-1.1-0.71.0-1.01.2-1.21.20.71.0-1.0-0.6-1.40.5-0.60.60.70.60.40.7
Parametrial fat weight0.71.44.92.2-1.6-1.30.30.5-0.9-1.81.6-1.60.6-0.60.71.30.9-0.9-1.4-0.81.7-1.31.30.80.41.1-0.4
Pavlov. Cond. lever latency3.34.211.00.7-3.3-2.91.81.9-2.5-2.21.1-1.12.1-2.12.12.42.1-2.1-2.5-2.00.9-2.62.61.80.62.10.7
Pavlov. Cond. magazine entry latency1.31.74.3-0.92.11.7-0.6-0.81.61.7-1.31.3-1.31.3-1.1-1.4-1.01.01.81.1-0.91.7-1.6-1.2-0.4-1.30.2
Pavlov. Cond. change in total contacts0.50.51.90.81.41.0-0.1-0.31.00.70.3-0.3-0.80.8-0.6-0.8-0.50.51.10.7-0.11.2-1.1-0.7-0.1-0.2-0.0
Pavlov. Cond. index score2.73.59.3-0.93.12.6-1.4-1.62.42.2-1.21.2-2.02.0-1.8-2.0-1.81.82.41.8-1.02.3-2.3-1.6-0.5-1.7-0.5
Pavlov. Cond. latency score2.83.69.6-0.53.12.7-1.5-1.72.42.1-0.90.9-2.02.0-1.8-2.1-1.91.92.51.8-0.92.4-2.4-1.7-0.5-1.9-0.5
Pavlov. Cond. lever contacts2.52.99.5-0.23.12.5-1.5-1.72.21.7-0.60.6-1.81.8-1.7-1.9-1.71.72.01.7-0.42.1-2.1-1.3-0.1-1.5-1.3
Pavlov. Cond. magazine entry number1.01.22.81.3-1.6-1.30.50.7-1.3-1.51.7-1.71.1-1.10.91.20.8-0.8-1.4-0.80.9-1.21.20.90.40.6-0.2
Pavlov. Cond. intertrial magazine entries0.20.31.0-0.8-0.8-0.8-0.4-0.2-0.1-0.1-1.01.0-0.30.3-0.1-0.10.1-0.1-0.40.0-0.3-0.30.2-0.1-0.80.40.5
Pavlov. Cond. lever-magazine prob. diff.2.83.59.1-1.03.02.6-1.4-1.62.52.2-1.31.3-2.12.1-1.8-2.0-1.81.82.41.8-1.02.3-2.3-1.6-0.5-1.6-0.4
Pavlov. Cond. response bias1.82.26.3-1.12.51.9-0.9-1.11.91.8-1.61.6-1.61.6-1.4-1.6-1.21.21.81.3-0.81.8-1.7-1.1-0.3-1.2-0.4
Pavlov. Cond. lever latency0.20.21.10.6-0.10.2-0.0-0.1-0.2-0.40.7-0.70.3-0.30.30.50.2-0.2-0.3-0.10.6-0.40.50.50.8-0.6-1.0
Pavlov. Cond. magazine entry latency0.20.20.91.00.70.3-0.1-0.10.40.00.9-0.9-0.30.3-0.2-0.5-0.20.20.30.20.30.6-0.6-0.3-0.0-0.0-0.0
Pavlov. Cond. change in total contacts0.20.21.70.5-0.3-0.70.60.6-0.3-0.10.3-0.30.2-0.20.2-0.20.3-0.3-0.1-0.3-0.20.2-0.2-0.2-0.50.91.3
Pavlov. Cond. index score0.10.10.60.20.2-0.20.10.10.20.2-0.00.0-0.20.2-0.1-0.5-0.10.10.30.1-0.20.4-0.5-0.4-0.50.50.7
Pavlov. Cond. latency score0.10.10.50.40.0-0.40.30.3-0.1-0.00.2-0.20.0-0.00.1-0.30.1-0.10.0-0.1-0.10.2-0.2-0.2-0.30.70.7
Pavlov. Cond. lever contacts0.20.32.4-0.3-0.4-0.60.00.1-0.00.2-0.50.5-0.30.3-0.2-0.4-0.20.20.10.1-0.60.2-0.3-0.6-1.10.61.6
Pavlov. Cond. magazine entry number0.10.10.6-0.7-0.2-0.10.20.2-0.30.0-0.50.50.3-0.30.20.40.3-0.3-0.2-0.3-0.1-0.40.40.30.3-0.1-0.2
Pavlov. Cond. intertrial magazine entries0.50.61.6-1.21.01.3-0.5-0.60.81.1-1.21.2-0.60.6-0.8-0.6-0.60.61.00.6-0.70.7-0.7-0.50.1-0.5-0.3
Pavlov. Cond. lever-magazine prob. diff.0.10.10.50.20.1-0.20.20.20.10.1-0.00.0-0.20.2-0.1-0.4-0.10.10.20.0-0.20.3-0.4-0.3-0.50.60.7
Pavlov. Cond. response bias0.40.51.9-0.20.30.1-0.4-0.40.60.6-0.50.5-0.70.7-0.7-0.8-0.70.70.70.6-0.80.8-0.8-1.0-1.20.11.4
Time in closed arm before self-admin0.10.10.30.10.0-0.20.30.3-0.2-0.10.2-0.20.3-0.30.30.10.4-0.4-0.1-0.50.1-0.00.00.20.20.2-0.2
Time in closed arm after self-admin0.30.30.90.7-0.3-0.40.40.4-0.5-0.61.0-1.00.5-0.50.80.40.6-0.6-0.5-0.60.4-0.40.40.40.30.2-0.2
Time in open arm before self-admin0.50.61.0-0.70.80.7-0.3-0.40.71.0-0.80.8-0.60.6-0.3-0.9-0.60.61.00.8-0.81.0-1.0-0.8-0.6-0.20.9
Time in open arm after self-admin0.40.41.4-1.00.5-0.00.20.20.10.8-1.01.0-0.20.2-0.5-0.9-0.30.30.60.0-0.70.7-0.7-0.6-0.70.21.2
Bone: periosteal estimation2.85.89.32.6-1.5-1.42.72.5-2.0-2.42.4-2.42.4-2.42.52.52.6-2.6-2.2-2.53.1-2.32.42.73.02.0-1.9
Bone: periosteal perimeter0.71.23.11.50.1-0.01.10.9-0.6-0.91.4-1.41.0-1.00.91.21.0-1.0-0.6-0.81.6-0.80.91.21.80.6-1.4
Bone: post-yield work0.40.62.60.0-0.20.10.50.4-0.4-0.4-0.70.70.6-0.60.90.70.7-0.7-0.6-0.61.2-0.80.81.11.40.5-1.6
Progressive ratio test 1 active lever presses0.10.10.8-0.50.90.10.00.00.10.4-0.20.2-0.10.1-0.1-0.5-0.00.00.20.3-0.40.4-0.4-0.1-0.10.2-0.1
Progressive ratio test 1 breakpoint0.10.10.5-0.50.7-0.00.20.20.00.3-0.10.10.0-0.00.2-0.30.2-0.20.10.1-0.30.2-0.20.10.10.4-0.3
Progressive ratio test 1 inactive lever presses0.10.10.5-0.1-0.7-0.3-0.1-0.0-0.1-0.1-0.50.5-0.00.00.30.20.2-0.2-0.2-0.3-0.1-0.30.30.0-0.20.40.1
Progressive ratio test 2 active lever presses0.70.81.5-1.00.30.5-0.9-0.90.70.8-1.11.1-0.90.9-0.9-0.9-0.90.90.81.2-1.00.8-0.8-0.9-1.0-0.50.6
Progressive ratio test 2 breakpoint1.21.42.3-1.30.30.7-1.2-1.11.01.1-1.51.5-1.21.2-1.2-1.2-1.21.21.01.5-1.31.0-1.0-1.3-1.4-0.70.9
Progressive ratio test 2 inactive lever presses0.10.10.90.61.00.10.10.10.10.10.3-0.3-0.10.1-0.2-0.60.0-0.00.30.10.30.6-0.6-0.2-0.1-0.40.1
Incentive Sensitization - Responses1.31.32.1-1.0-0.10.9-1.2-1.21.11.0-1.11.1-1.21.2-1.3-1.0-1.31.31.11.5-1.40.9-0.9-1.4-1.4-1.01.1
Incentive Sensitization - Breakpoint1.51.52.6-1.1-0.11.0-1.4-1.41.21.0-1.31.3-1.41.4-1.4-1.0-1.41.41.21.6-1.30.9-0.9-1.4-1.4-1.11.0
Sum of active levers in priming session hrs 5-60.10.10.6-0.60.70.10.30.3-0.00.4-0.20.20.2-0.20.3-0.3-0.00.00.2-0.2-0.40.3-0.30.10.2-0.1-0.0
Progressive ratio4.85.512.02.6-3.5-2.62.22.2-2.5-2.92.1-2.12.3-2.32.42.82.0-2.0-2.6-2.02.1-2.82.82.01.32.40.3
Food seeking constrained by brief footshock0.10.10.40.1-0.4-0.50.30.4-0.3-0.10.1-0.10.2-0.20.40.00.1-0.1-0.2-0.40.3-0.20.10.1-0.20.60.4
Seeking ratio, punishment vs. effort2.73.36.7-2.42.61.9-1.5-1.61.92.4-1.81.8-1.71.7-1.6-2.2-1.41.42.11.3-1.82.1-2.1-1.6-1.0-1.7-0.1
Retroperitoneal fat weight0.41.32.01.1-0.9-1.41.11.2-1.2-1.30.8-0.81.1-1.11.21.31.4-1.4-1.4-1.21.2-1.21.21.20.81.4-0.4
Reaction time number correct0.91.23.8-0.1-1.9-1.81.11.2-1.4-1.10.2-0.21.1-1.11.31.11.1-1.1-1.4-0.90.2-1.41.41.00.21.00.6
Reaction time mean minus median1.21.63.6-0.11.81.9-1.3-1.41.81.3-0.70.7-1.51.5-1.3-1.3-1.41.41.61.10.01.5-1.5-1.1-0.3-0.8-0.4
Reaction time mean minus median AUC1.62.04.8-0.32.21.9-1.4-1.51.91.5-0.90.9-1.71.7-1.5-1.7-1.61.61.61.2-0.11.8-1.8-1.2-0.5-0.8-0.5
Reaction time num false alarms0.10.20.70.80.30.7-0.0-0.20.30.10.8-0.8-0.10.1-0.1-0.1-0.30.30.50.20.20.4-0.3-0.20.2-0.8-0.2
Reaction time num false alarms AUC0.20.21.51.1-0.00.50.40.20.1-0.11.2-1.20.2-0.20.20.2-0.00.00.3-0.10.20.2-0.1-0.10.4-0.6-0.1
Reaction time trials correct on left0.91.23.8-0.1-1.9-1.81.11.2-1.4-1.10.2-0.21.1-1.11.31.11.1-1.1-1.4-0.90.2-1.41.41.00.21.00.6
Reaction time trials on left0.91.33.7-0.0-1.9-1.81.11.2-1.4-1.10.2-0.21.2-1.21.41.11.2-1.2-1.4-0.90.2-1.41.41.00.31.10.5
Reaction time mean1.31.85.7-0.62.42.2-1.5-1.61.71.3-1.11.1-1.31.3-1.2-1.0-1.31.31.41.10.31.3-1.3-0.60.4-1.3-1.7
Reaction time mean AUC1.31.75.7-0.52.42.0-1.4-1.51.71.3-1.11.1-1.31.3-1.3-1.1-1.31.31.31.00.31.3-1.2-0.60.3-1.1-1.6
Median of all reaction times0.81.13.8-0.52.01.7-1.2-1.31.30.9-1.01.0-0.90.9-0.9-0.6-0.90.90.90.80.40.8-0.8-0.20.6-1.2-1.8
Reaction time omissions0.70.92.5-0.21.41.6-1.1-1.21.30.9-0.80.8-1.01.0-1.1-0.9-0.90.91.10.90.21.0-1.0-0.60.0-0.7-0.9
Reaction time false alarm rate0.40.62.10.91.21.4-0.2-0.40.80.61.0-1.0-0.40.4-0.6-0.5-0.60.61.10.40.10.9-0.9-0.50.3-1.0-0.4
Reaction time premature initiation rate0.91.22.81.7-0.6-0.90.91.0-1.1-1.21.4-1.41.2-1.21.20.81.1-1.1-1.1-0.71.4-0.80.81.11.00.6-1.0
Reaction time premature initiations2.02.83.91.7-1.7-1.91.61.7-2.0-1.91.5-1.51.9-1.92.01.61.9-1.9-2.0-1.41.5-1.71.71.71.21.3-0.7
Std. dev. reaction times0.91.24.30.02.11.9-0.8-1.01.51.2-0.50.5-1.11.1-1.0-1.1-1.01.01.50.70.31.4-1.4-0.70.2-0.8-0.8
Reaction time trials completed0.91.33.7-0.0-1.9-1.81.11.2-1.4-1.10.2-0.21.2-1.21.41.11.2-1.2-1.4-0.90.2-1.41.41.00.31.10.5
Reaction time trials AUC0.81.13.4-0.1-1.8-1.71.01.1-1.4-1.10.1-0.11.1-1.11.31.11.1-1.1-1.4-0.80.1-1.41.31.00.31.00.5
Run reversals in cocaine runway, females0.10.10.60.0-0.6-0.7-0.00.1-0.3-0.1-0.30.30.0-0.00.2-0.20.1-0.1-0.30.1-0.4-0.10.1-0.1-0.70.60.8
Run reversals in cocaine runway, males0.30.31.51.20.70.7-0.3-0.40.50.10.6-0.6-0.40.4-0.3-0.5-0.40.40.50.40.60.7-0.7-0.30.1-1.2-0.2
Latency to leave start box in cocaine runway0.50.61.60.71.31.2-0.7-0.80.90.21.0-1.0-0.60.6-0.6-0.4-0.60.60.70.90.10.7-0.7-0.40.2-0.6-1.0
Latency to leave start box in cocaine runway, F0.80.82.0-0.11.31.4-1.0-1.11.20.7-0.00.0-1.01.0-0.9-0.8-1.11.11.01.4-0.30.9-0.9-0.7-0.2-0.8-0.8
Latency to leave start box in cocaine runway, M0.30.32.31.2-0.10.10.0-0.00.0-0.61.5-1.50.0-0.0-0.00.30.1-0.1-0.1-0.20.4-0.10.10.10.2-0.1-0.3
Std. dev. time between licks in bursts0.50.63.80.31.41.10.50.30.10.10.7-0.70.4-0.40.30.20.4-0.40.3-0.40.90.1-0.00.71.7-0.3-2.0
Total sessions with >9 infusions0.10.11.20.11.1-0.00.00.1-0.00.10.0-0.00.1-0.1-0.0-0.40.3-0.3-0.00.0-0.10.3-0.30.10.20.4-0.4
Short access day 1 total inactive lever presses0.40.54.80.42.20.8-0.0-0.10.50.40.1-0.1-0.10.1-0.1-0.60.2-0.20.4-0.30.80.6-0.60.20.9-0.5-1.6
Short access day 10 total inactive lever presses0.10.20.80.1-0.40.8-0.4-0.50.5-0.0-0.00.0-0.40.4-0.10.4-0.30.30.30.50.1-0.10.2-0.00.4-0.9-0.4
Short access day 1 total infusions0.30.33.3-0.61.80.20.20.20.10.7-0.20.20.1-0.1-0.1-0.90.1-0.10.4-0.0-0.30.8-0.8-0.10.10.3-0.4
Short access day 10 total infusions0.00.00.30.20.5-0.10.20.2-0.1-0.00.2-0.20.1-0.10.0-0.10.3-0.3-0.1-0.20.00.1-0.10.20.20.5-0.3
Short access total infusions0.20.21.30.21.2-0.30.60.6-0.30.10.4-0.40.4-0.40.3-0.30.5-0.5-0.1-0.3-0.00.3-0.30.20.30.7-0.3
Short access day 1 locomotion1.51.74.5-2.11.31.5-1.2-1.31.41.5-1.81.8-1.31.3-1.2-1.1-1.11.11.21.1-1.51.0-1.0-0.8-0.4-1.1-0.4
Short access day 10 total locomotion1.51.74.70.2-0.6-0.41.61.5-1.1-0.80.8-0.81.5-1.51.71.61.6-1.6-1.0-1.20.9-1.31.41.72.21.1-1.4
Short access total locomotion0.60.61.9-0.4-0.1-0.30.80.8-0.6-0.30.0-0.00.8-0.81.00.81.0-1.0-0.7-0.80.4-0.80.81.21.40.9-1.2
One hour access (0.3 mA shock)2.22.66.0-0.91.11.8-1.9-2.01.81.4-1.01.0-1.81.8-1.8-1.4-1.91.91.62.5-1.41.4-1.4-1.6-1.2-1.70.2
Compulsive drug intake1.81.94.9-1.91.12.2-1.5-1.71.71.4-1.01.0-1.41.4-1.5-0.6-1.51.51.51.7-1.40.9-0.8-0.9-0.1-1.6-0.8
One hour access (shock baseline)0.10.10.80.90.1-0.60.10.2-0.4-0.30.1-0.10.2-0.20.2-0.20.1-0.1-0.30.00.50.1-0.1-0.1-0.4-0.00.5
Social response proportion1.21.32.70.10.1-0.71.41.3-1.1-0.81.2-1.21.3-1.31.21.31.3-1.3-1.1-1.21.0-1.11.11.51.60.6-1.2
Social responses0.91.22.30.4-0.2-0.81.51.4-1.0-0.81.5-1.51.2-1.21.11.31.3-1.3-0.9-1.20.6-0.91.01.11.20.8-0.5
Social time0.70.93.70.41.51.9-0.8-1.01.30.50.9-0.9-0.80.8-0.8-0.3-0.60.61.00.70.60.7-0.7-0.30.7-1.2-1.7
Soleus weight0.72.012.91.01.61.30.90.6-0.3-0.50.8-0.81.1-1.10.81.10.7-0.7-0.3-1.02.1-0.70.81.93.3-0.6-3.6
Bone: stiffness0.60.92.91.4-1.7-1.00.40.5-0.9-1.30.8-0.80.7-0.70.91.20.6-0.6-1.2-0.70.9-1.31.30.70.31.2-0.2
Tibialis anterior weight0.00.10.60.1-0.7-0.3-0.3-0.20.0-0.1-0.50.5-0.20.2-0.4-0.0-0.10.1-0.10.1-0.4-0.00.0-0.4-0.70.30.7
Time to tail flick, vehicle, before self-admin1.21.33.2-0.10.11.5-1.7-1.81.40.5-0.80.8-1.41.4-1.4-0.4-1.61.61.01.6-0.30.7-0.7-1.1-0.7-0.7-0.2
Time to tail flick, vehicle, after self-admin0.50.61.5-0.71.11.2-0.8-0.90.90.8-0.90.9-0.70.7-0.6-0.4-0.70.70.80.8-0.20.6-0.6-0.40.1-1.0-0.6
Time to tail flick, test, before self-admin0.40.40.80.0-0.30.3-0.6-0.70.50.1-0.00.0-0.70.7-0.8-0.2-0.90.90.50.8-0.60.4-0.4-0.8-0.90.20.9
Time to tail flick, test, after self-admin2.82.94.2-1.11.21.5-1.7-1.71.71.8-2.02.0-1.91.9-1.5-2.0-1.81.81.81.5-1.21.9-1.9-1.9-1.8-0.91.3
Delta time to tail flick, vehicle, before/after SA0.40.41.4-0.81.20.3-0.2-0.20.40.9-0.60.6-0.30.3-0.1-1.0-0.30.30.60.3-0.60.8-0.8-0.4-0.4-0.80.4
Delta time to tail flick, test, before/after SA0.80.72.5-1.00.50.6-1.1-1.00.80.9-1.61.6-0.90.9-0.7-1.0-0.70.70.60.7-0.40.7-0.7-0.7-0.8-0.30.1
Tibia length2.67.413.32.8-1.4-1.52.82.7-2.0-2.82.7-2.72.4-2.42.62.83.0-3.0-2.5-2.93.6-2.62.63.23.72.6-2.8
Ambulatory time before self-admin0.10.10.5-0.10.00.5-0.6-0.60.40.0-0.40.4-0.40.4-0.7-0.1-0.40.40.10.50.10.0-0.0-0.10.0-0.6-0.2
Ambulatory time after self-admin0.70.81.90.6-1.0-0.71.11.1-1.0-0.80.5-0.51.1-1.10.80.91.0-1.0-0.8-1.41.0-0.91.00.90.90.0-0.1
Bone: tissue strength0.80.85.12.3-0.2-0.60.30.3-0.4-1.12.0-2.00.3-0.30.50.30.3-0.3-0.7-0.41.3-0.30.30.40.30.7-0.3
Total heroin consumption0.10.10.5-0.10.10.1-0.1-0.10.10.2-0.40.4-0.10.10.0-0.1-0.10.10.10.7-0.60.1-0.1-0.1-0.1-0.00.6
Bone: trabecular number2.94.67.8-1.70.81.5-2.8-2.61.91.9-2.02.0-2.42.4-2.2-2.4-2.52.51.82.5-2.11.9-1.9-2.4-2.6-1.81.5
Bone: trabecular spacing3.85.07.52.6-0.9-1.62.62.5-1.8-2.22.7-2.72.1-2.12.22.52.5-2.5-2.0-2.52.4-1.91.92.32.42.0-1.4
Bone: trabecular thickness1.51.93.6-1.30.30.9-1.9-1.81.01.2-1.51.5-1.31.3-1.5-1.6-1.61.61.11.5-1.31.2-1.2-1.5-1.7-1.10.7
Bone: trabecular tissue density0.70.93.71.7-0.9-0.81.31.2-0.9-0.81.9-1.91.0-1.01.10.30.8-0.8-0.4-0.60.4-0.20.20.30.20.20.9
Water consumed over 24 hours0.10.10.50.10.70.6-0.1-0.20.40.20.3-0.3-0.20.2-0.10.0-0.10.10.2-0.10.20.2-0.20.10.4-0.7-0.7
Number of responses in last shaping day0.60.61.70.41.00.11.11.0-0.4-0.21.0-1.00.8-0.80.80.41.0-1.0-0.1-1.30.50.00.00.81.30.2-1.0