Hub : Genes

Atp1b3

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Liver mRNA stability Atp1b3 0.06 0.03 4.4e-05 0.05 0.03 0.02 0.03 5.0e-06 1.6e-04 1.0e-03 2.2e-04
2 IC mRNA stability Atp1b3 0.13 0.06 5.1e-05 0.09 0.09 0.08 0.11 1.2e-04 1.3e-04 2.7e-04 1.8e-05
3 Brain intron excision ratio chr8_105802082_105820898 0.05 0.03 3.7e-05 0.03 0.05 0.04 0.04 3.6e-04 1.8e-05 3.0e-04 2.3e-04
4 Brain mRNA stability Atp1b3 0.46 0.11 0.0e+00 0.37 0.39 0.42 0.42 2.2e-36 6.9e-39 2.2e-42 1.0e-42
5 pVTA intron excision ratio chr8_105802082_105820898 0.03 0.02 4.7e-03 0.02 0.01 0.01 0.01 4.3e-03 2.0e-02 8.8e-02 3.1e-02
6 Brain gene expression Atp1b3 0.07 0.04 3.1e-04 0.04 0.05 0.05 0.05 3.2e-04 3.5e-05 1.4e-05 1.4e-05
7 pVTA mRNA stability Atp1b3 0.14 0.06 2.1e-13 0.17 0.17 0.16 0.18 6.6e-14 6.1e-14 4.9e-13 8.8e-15
8 PL mRNA stability Atp1b3 0.16 0.07 0.0e+00 0.2 0.19 0.19 0.19 7.0e-22 2.9e-20 1.6e-20 1.8e-20
9 BLA mRNA stability Atp1b3 0.07 0.04 5.1e-04 0.07 0.06 0.07 0.07 2.0e-04 3.0e-04 1.2e-04 1.1e-04
10 OFC mRNA stability Atp1b3 0.38 0.12 2.7e-07 0.27 0.27 0.25 0.28 4.1e-07 3.5e-07 1.3e-06 2.5e-07
11 IL mRNA stability Atp1b3 0.27 0.12 8.3e-04 0.07 0.09 0.07 0.07 7.5e-03 3.1e-03 1.1e-02 9.4e-03
12 Brain intron excision ratio chr8_105802082_105803352 0.04 0.02 3.2e-04 0.04 0.04 0.02 0.03 1.1e-04 1.5e-04 7.7e-03 5.3e-04
13 pVTA gene expression Atp1b3 0.04 0.03 1.6e-03 0.02 0.02 0.02 0.02 4.5e-03 5.2e-03 5.5e-03 1.2e-02
14 NAcc mRNA stability Atp1b3 0.12 0.05 0.0e+00 0.15 0.14 0.15 0.15 7.8e-22 3.2e-21 2.0e-22 1.3e-22
15 Liver gene expression Atp1b3 0.29 0.09 0.0e+00 0.19 0.19 0.17 0.19 1.1e-20 2.1e-20 3.4e-18 9.9e-21
16 Adipose gene expression Atp1b3 0.1 0.05 2.1e-10 0.09 0.08 0.08 0.08 6.0e-10 3.7e-09 8.7e-09 3.9e-09
17 BLA gene expression Atp1b3 0.14 0.07 3.9e-05 0.08 0.09 0.09 0.09 3.1e-05 2.6e-05 2.3e-05 2.4e-05
18 IL gene expression Atp1b3 0.16 0.09 5.3e-03 0.12 0.05 0.04 0.06 7.6e-04 2.1e-02 4.1e-02 1.7e-02
19 PL gene expression Atp1b3 0.16 0.06 0.0e+00 0.18 0.19 0.17 0.19 4.9e-19 3.1e-20 1.5e-18 5.3e-20
20 IC gene expression Atp1b3 0.11 0.06 5.9e-03 0.04 0.02 0.02 0.04 7.2e-03 3.3e-02 3.5e-02 1.0e-02

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20
Bone: apparent density0.71.22.1-1.5-1.51.4-1.41.3-1.1-1.5-1.2-1.2-1.2-1.2-1.1-1.1-1.20.30.5-0.10.10.3-0.8
Area under the delay curve0.30.30.8-0.6-0.60.6-0.50.9-0.5-0.8-0.6-0.5-0.6-0.5-0.5-0.4-0.80.40.10.40.60.2-0.3
BMI with tail6.622.636.55.25.2-5.85.8-6.05.75.36.05.85.65.45.25.25.1-1.9-2.4-1.5-1.8-2.41.5
BMI without tail3.911.828.23.73.7-4.34.4-4.45.33.84.44.13.93.83.33.23.60.2-0.40.50.1-0.42.8
Body weight3.816.633.54.54.5-5.35.2-5.15.84.94.94.84.64.64.03.94.4-0.4-1.10.4-0.2-0.63.6
Weight adjusted by age1.11.73.41.51.5-1.51.6-1.51.81.71.51.51.31.51.00.91.5-0.2-0.20.3-0.10.11.7
Bone surface1.32.33.6-1.8-1.81.7-1.81.9-1.3-1.7-1.9-1.8-1.6-1.4-1.4-1.4-1.91.21.40.91.01.10.4
Bone volume0.91.62.6-1.6-1.61.5-1.61.5-1.2-1.5-1.5-1.5-1.4-1.3-1.2-1.2-1.50.70.90.50.50.7-0.1
Breakpoint value in progressive ratio session0.30.31.2-0.7-0.70.7-0.70.4-1.1-0.7-0.4-0.5-0.4-0.4-0.2-0.1-0.6-0.3-0.3-0.3-0.3-0.3-0.8
Number of licking bursts0.50.82.4-0.6-0.60.4-0.40.70.3-0.5-0.7-0.6-0.6-0.5-0.6-0.5-0.81.51.31.61.41.21.3
Context. condit. distance diff. score0.70.92.80.30.3-0.3-0.1-0.2-1.00.30.10.10.50.30.80.90.5-1.7-1.7-1.5-1.6-1.5-1.2
Locomotion velocity, session 11.92.03.11.71.7-1.21.6-1.51.31.51.61.61.51.81.41.51.5-1.2-1.4-1.0-0.8-1.3-0.6
Locomotion distance, session 13.94.96.72.32.3-2.32.3-2.61.72.22.62.52.62.42.52.62.4-1.9-2.0-1.7-1.8-2.1-0.8
Locomotion velocity, session 25.96.913.13.63.6-2.63.0-2.61.93.12.62.92.73.32.62.72.6-2.1-2.3-1.7-1.5-2.4-0.5
Locomotion distance, session 25.67.812.43.13.1-3.13.1-3.22.73.03.33.33.23.53.13.13.0-1.7-2.0-1.6-1.6-2.3-0.1
Locomotion velocity, session 30.80.92.41.11.1-0.81.0-0.51.50.60.50.70.80.91.21.2-0.11.10.71.21.3-0.10.6
Locomotion distance, session 30.10.10.50.50.5-0.40.3-0.10.20.40.00.20.20.50.40.40.10.30.20.40.2-0.10.7
Stereotopy head waving bouts, day 32.83.314.1-0.1-0.1-0.40.50.32.10.0-0.3-0.2-0.20.3-0.1-0.2-0.83.12.83.53.32.33.7
Stereotopy head waving duration, day 31.82.17.30.40.3-0.61.0-0.42.40.40.50.50.50.70.40.3-0.22.32.02.62.61.52.7
Locomotion velocity, session 74.14.46.52.52.5-1.92.4-2.31.82.12.32.42.31.82.12.12.1-1.8-2.1-1.8-1.7-2.0-1.5
Locomotion distance, session 71.01.33.41.81.8-0.81.3-0.90.61.50.91.20.70.90.30.31.3-1.4-1.5-1.2-1.2-0.9-0.6
Stereotopy head waving bouts, day 71.72.05.7-2.4-2.41.5-1.81.5-1.1-2.2-1.4-1.7-0.9-0.9-0.2-0.2-1.71.21.11.01.20.3-0.2
Stereotopy head waving duration, day 72.53.07.0-2.6-2.61.8-2.01.6-0.9-2.5-1.6-1.9-1.2-1.5-0.6-0.5-2.11.91.81.71.80.9-0.0
Locomotion velocity, session 82.83.36.22.42.4-1.01.6-1.50.71.61.51.61.71.61.92.01.3-1.9-2.0-2.1-1.7-2.5-2.4
Locomotion distance, session 82.43.55.22.12.1-1.71.6-1.70.61.81.71.71.91.72.12.21.8-2.1-2.2-2.0-2.0-2.3-1.2
Degree of sensitization distance1.01.02.51.11.1-0.30.8-0.70.10.90.80.90.40.1-0.0-0.01.0-1.6-1.6-1.6-1.5-0.9-1.4
Degree of sensitization stereotypy1.21.33.6-1.9-1.91.1-1.50.8-1.6-1.6-0.7-1.1-0.3-0.40.40.5-0.8-0.5-0.6-0.8-0.6-1.2-1.9
Conditioned locomotion0.81.05.0-0.9-0.91.2-0.90.4-1.4-0.9-0.5-0.6-0.6-0.7-0.6-0.7-0.2-1.1-0.9-1.3-1.1-0.8-2.2
Cocaine response after cond. corrected0.30.41.7-0.2-0.2-0.20.4-0.11.0-0.10.10.1-0.0-0.0-0.00.0-0.11.31.11.21.10.80.9
Cocaine response after cond. not corrected0.60.72.70.00.0-0.30.5-0.11.40.00.20.1-0.10.1-0.2-0.0-0.01.61.31.71.51.21.3
Cocaine response before conditioning0.30.31.30.20.2-0.20.2-0.00.70.10.10.1-0.20.2-0.2-0.10.00.90.91.11.10.81.0
Saline control response1.41.92.91.31.3-1.61.5-1.71.31.41.71.51.61.61.61.61.7-0.9-1.0-1.1-1.2-1.10.2
Bone: connectivity density1.11.73.1-1.7-1.71.7-1.61.6-1.6-1.6-1.5-1.4-1.4-1.4-1.2-1.2-1.40.10.3-0.3-0.10.1-1.1
Bone: cortical apparent density0.20.31.7-0.0-0.00.4-0.2-0.0-0.7-0.10.1-0.0-0.1-0.1-0.1-0.00.2-0.9-0.8-0.9-0.9-0.7-1.3
Bone: cortical area1.92.95.61.31.3-1.61.5-1.91.21.41.81.72.21.82.42.41.6-1.5-1.7-1.6-1.7-2.1-1.0
Bone: cortical porosity1.92.15.20.90.9-0.90.7-1.0-0.40.91.01.01.31.21.31.21.2-2.3-2.2-2.2-2.1-2.1-1.7
Bone: cortical porosity3.03.28.80.80.8-0.90.7-1.2-0.80.81.11.11.51.31.61.51.5-3.0-2.9-2.9-2.8-2.7-2.5
Bone: cortical thickness1.01.62.91.21.2-1.31.4-1.51.31.11.51.41.61.31.71.71.2-0.9-1.1-0.9-1.0-1.4-0.6
Bone: cortical thickness0.20.31.60.10.10.00.2-0.30.00.10.40.30.30.40.30.20.3-0.8-1.0-0.6-0.6-0.9-1.3
Bone: cortical tissue density0.20.31.7-0.0-0.00.4-0.20.0-0.7-0.10.0-0.0-0.1-0.2-0.1-0.00.1-0.8-0.8-0.8-0.9-0.7-1.3
Condit. Reinf. active minus inactive responses0.10.10.80.60.6-0.30.5-0.30.90.40.40.40.30.40.20.20.10.20.20.20.3-0.10.2
Condit. Reinf. active-inactive response ratio2.62.84.52.12.1-1.72.0-1.92.11.82.02.01.91.91.81.81.6-0.8-0.9-0.8-0.8-1.3-0.3
Condit. Reinf. active responses0.00.10.2-0.1-0.10.20.00.10.3-0.3-0.1-0.1-0.1-0.1-0.2-0.2-0.40.40.40.30.50.1-0.1
Condit. Reinf. inactive responses1.92.43.5-1.8-1.81.6-1.61.6-1.4-1.9-1.7-1.7-1.7-1.6-1.7-1.8-1.71.11.21.11.21.30.1
Incentive salience index mean0.70.91.81.21.2-1.11.1-1.01.31.11.01.11.11.31.11.10.7-0.4-0.4-0.1-0.1-0.70.1
Condit. Reinf. lever presses2.02.85.11.81.8-2.01.8-1.91.71.71.91.82.02.32.22.11.6-1.0-1.2-0.6-0.7-1.40.0
Condit. Reinf. active minus inactive responses0.70.92.9-0.8-0.80.3-0.30.30.5-0.8-0.3-0.5-0.4-0.5-0.6-0.5-0.81.51.51.71.71.30.9
Condit. Reinf. active-inactive response ratio1.11.34.90.00.0-0.50.7-0.51.8-0.10.50.30.20.0-0.10.0-0.31.91.72.22.21.51.4
Condit. Reinf. active responses0.91.21.9-1.4-1.40.8-1.21.0-0.5-1.3-0.9-1.1-0.9-1.0-0.9-0.9-1.21.31.41.31.31.10.6
Condit. Reinf. inactive responses0.60.82.5-0.8-0.81.0-1.31.2-1.6-0.8-1.1-1.1-1.0-1.0-0.8-0.7-0.8-0.3-0.0-0.6-0.6-0.1-0.6
Condit. Reinf. lever presses0.60.82.7-0.3-0.3-0.1-0.20.50.5-0.4-0.5-0.4-0.3-0.6-0.2-0.1-0.81.61.51.61.51.31.4
Condit. Reinf. lever reinforcers received0.60.81.3-1.2-1.20.6-1.00.8-0.4-1.1-0.7-1.0-0.7-0.9-0.7-0.6-1.01.01.11.11.00.90.4
Conditioned reinforcement - actives0.50.92.8-0.7-0.70.4-0.30.90.1-0.7-0.9-0.8-0.9-0.7-0.6-0.7-0.71.51.71.51.41.31.2
Conditioned reinforcement - inactives0.00.00.1-0.3-0.3-0.3-0.1-0.10.1-0.10.1-0.00.20.10.30.3-0.00.20.30.20.20.10.4
Conditioned locomotion0.20.20.6-0.4-0.40.6-0.40.7-0.6-0.5-0.8-0.6-0.5-0.4-0.4-0.4-0.50.00.2-0.3-0.1-0.1-0.7
Patch foraging indifference point 0 sec0.00.00.10.20.2-0.00.2-0.10.10.20.20.1-0.1-0.1-0.1-0.10.3-0.2-0.2-0.3-0.20.1-0.1
Patch foraging indifference point AUC0.40.52.30.30.30.00.2-0.3-0.70.20.40.50.3-0.10.10.10.4-1.3-1.1-1.2-1.3-1.1-1.5
Delay disc. indifference point, 0s delay1.21.32.3-1.1-1.11.2-1.21.3-0.9-1.3-1.3-1.3-1.2-1.3-1.0-0.9-1.51.01.01.01.21.00.1
Delay disc. indifference point, 16s delay0.10.20.50.30.3-0.40.6-0.30.70.10.60.60.50.30.60.50.00.40.10.30.4-0.10.1
Delay disc. indifference point, 2s delay0.40.41.20.60.6-0.70.8-0.31.10.40.20.40.50.50.40.50.10.70.30.81.00.41.0
Delay disc. indifference point, 24s delay0.40.51.6-0.3-0.30.5-0.30.5-1.0-0.3-0.1-0.1-0.3-0.2-0.4-0.30.2-1.1-1.2-1.1-1.0-0.8-1.2
Delay disc. indifference point, 4s delay2.12.24.2-1.5-1.51.5-1.41.4-0.8-1.8-1.6-1.6-1.3-1.4-1.3-1.3-2.01.61.31.82.01.40.1
Delay disc. indifference point, 8s delay0.20.20.7-0.6-0.60.5-0.50.8-0.8-0.6-0.4-0.4-0.7-0.4-0.4-0.4-0.5-0.1-0.1-0.10.0-0.0-0.4
Indifference point function ln k0.50.84.50.10.1-0.40.4-0.11.20.30.10.00.00.5-0.0-0.00.01.41.11.61.61.32.1
Indifference point function log k0.50.84.50.10.1-0.40.4-0.11.20.30.10.00.00.5-0.0-0.00.01.41.11.61.61.32.1
Patch foraging total patch changes 0 sec0.10.10.20.40.4-0.40.5-0.40.40.40.50.40.30.20.20.30.5-0.2-0.3-0.2-0.2-0.00.0
Patch foraging total patch changes 12 sec1.41.86.20.70.7-0.30.3-0.5-1.10.70.70.60.70.40.50.51.0-2.5-2.3-2.4-2.4-1.8-1.9
Patch foraging total patch changes 18 sec0.20.31.10.40.40.10.2-0.2-0.40.30.30.4-0.0-0.2-0.2-0.20.3-1.0-0.8-1.0-1.0-0.5-0.9
Patch foraging total patch changes 24 sec0.10.20.7-0.1-0.10.4-0.40.3-0.5-0.3-0.2-0.2-0.4-0.9-0.4-0.5-0.4-0.4-0.2-0.4-0.40.0-0.6
Patch foraging total patch changes 6 sec0.10.21.3-0.1-0.10.7-0.20.2-0.4-0.2-0.3-0.3-0.3-0.7-0.4-0.5-0.1-0.4-0.3-0.7-0.6-0.3-1.1
Patch foraging time to switch 0 sec1.22.45.2-1.5-1.52.1-2.11.9-2.3-1.8-1.9-1.8-1.8-1.6-1.6-1.5-1.6-0.10.0-0.5-0.20.1-1.6
Patch foraging water rate 0 sec0.81.64.81.21.2-1.61.7-1.52.21.41.51.51.31.01.00.91.20.60.61.00.70.51.8
Patch foraging water rate 12 sec0.91.95.61.41.4-1.71.7-1.42.41.51.21.21.31.31.31.21.11.10.91.00.80.62.1
Patch foraging water rate 18 sec2.23.47.31.91.9-2.52.4-2.32.72.12.22.12.11.82.01.92.10.0-0.10.3-0.1-0.11.7
Patch foraging water rate 24 sec0.71.03.40.50.5-1.01.0-0.91.80.50.80.70.80.30.60.50.41.31.21.31.11.01.9
Patch foraging water rate 6 sec1.31.96.20.80.8-1.81.5-1.22.31.01.21.11.20.91.21.10.71.31.11.71.51.02.5
Seeking ratio, delayed vs. immediate footshock1.72.112.2-0.2-0.21.0-0.60.1-1.6-0.5-0.2-0.20.2-0.30.30.20.1-2.2-1.9-2.6-2.4-2.2-3.5
Distance traveled before self-admin1.01.32.51.11.1-0.80.8-1.10.31.01.00.91.10.91.11.21.0-1.5-1.4-1.5-1.6-1.4-1.1
Distance traveled after self-admin0.10.10.40.20.20.1-0.10.0-0.20.2-0.1-0.1-0.10.2-0.1-0.00.2-0.6-0.7-0.6-0.6-0.3-0.2
Extensor digitorum longus weight1.97.412.32.52.5-3.53.2-3.33.32.83.33.23.43.33.43.52.8-1.0-1.5-0.9-1.0-1.61.1
Bone: elastic displacement2.63.04.31.71.7-1.81.7-1.81.01.81.91.81.81.71.71.82.1-1.8-1.9-1.7-1.9-1.6-0.4
Bone: elastic work1.41.82.71.21.2-1.41.4-1.51.01.31.51.41.51.41.61.71.5-1.1-1.3-1.1-1.2-1.2-0.3
Bone: endosteal estimation0.20.51.30.50.5-0.80.6-0.90.70.60.70.71.01.21.11.10.6-0.2-0.2-0.2-0.1-0.60.1
Bone: endosteal perimeter1.12.34.51.11.1-1.61.3-1.70.91.31.51.51.91.82.12.11.5-1.4-1.5-1.4-1.4-1.7-0.4
Epididymis fat weight0.62.14.51.61.6-1.51.7-2.01.81.62.11.91.81.21.41.21.5-0.7-0.8-0.7-0.7-0.8-0.2
Delta time in closed arm before/after self-admin0.60.51.9-0.1-0.10.1-0.30.1-1.20.0-0.3-0.20.2-0.00.60.5-0.0-1.1-0.9-1.1-1.2-1.3-1.4
Delta time in open arm before/after self-admin0.30.30.9-0.4-0.40.6-0.50.8-0.7-0.3-0.8-0.7-0.8-0.5-0.9-0.80.0-0.4-0.2-0.5-0.60.1-0.2
Diff in mean of infusions in LGA sessions0.30.40.9-0.9-0.90.7-0.70.7-0.7-0.9-0.7-0.7-0.4-0.4-0.10.1-0.80.70.60.40.50.0-0.3
Delay discount exponential model param0.20.30.70.50.5-0.50.4-0.90.50.70.50.40.60.40.50.50.7-0.30.0-0.4-0.6-0.20.2
Extinction: sum of active levers before priming1.11.24.30.70.7-0.60.4-0.9-0.40.90.90.70.80.50.81.01.1-1.9-1.7-1.9-2.1-1.2-0.7
Active lever presses in extinction session 60.70.73.40.10.10.0-0.1-0.2-1.10.10.30.20.20.20.20.30.4-1.7-1.8-1.5-1.3-1.0-1.1
Bone: final force0.30.41.80.30.3-0.40.6-0.41.30.20.30.30.50.50.70.7-0.11.00.81.00.90.10.7
Bone: final moment0.40.73.00.50.5-0.60.8-0.61.70.40.50.50.70.70.80.80.01.20.91.11.10.30.9
Food consumed during 24 hour testing period1.01.42.4-1.4-1.40.7-1.01.2-0.4-1.2-1.2-1.2-1.2-1.5-1.0-1.0-1.21.41.41.21.11.51.0
Glucose0.40.61.30.70.7-0.91.0-1.11.10.61.11.11.00.51.01.00.7-0.0-0.2-0.2-0.1-0.4-0.1
Heart weight0.71.11.91.31.3-1.41.3-1.41.41.31.21.11.21.01.01.11.2-0.0-0.30.50.2-0.00.8
Delay discount hyperbolic model param0.30.30.80.60.6-0.50.4-0.90.40.70.60.50.60.50.60.50.8-0.5-0.2-0.7-0.9-0.5-0.1
Intermittent access intake day 1-15 change0.10.10.3-0.1-0.10.4-0.50.3-0.4-0.4-0.3-0.3-0.4-0.5-0.3-0.3-0.4-0.10.2-0.1-0.10.0-0.5
Intermittent access intake escalation0.00.10.3-0.1-0.10.4-0.40.3-0.3-0.3-0.3-0.3-0.4-0.6-0.4-0.3-0.40.10.3-0.10.00.1-0.3
Intermittent access intake escalation 20.91.01.7-1.1-1.11.3-1.31.2-1.3-1.1-1.3-1.3-1.3-1.1-1.0-1.0-1.10.40.80.30.30.5-0.1
Intermitt. access day 1 inactive lever presses0.20.62.00.20.2-0.3-0.1-0.7-0.10.20.70.50.60.60.70.70.5-1.3-1.1-1.4-1.2-1.1-1.0
Intermitt. access day 15 inactive lever presses0.30.62.0-1.0-1.00.8-1.20.5-1.4-0.9-0.6-0.7-0.4-0.00.0-0.1-0.8-0.6-0.6-0.5-0.3-0.7-1.1
Intermitt. access escalation Index1.11.62.9-1.4-1.41.3-1.30.9-0.6-1.4-0.9-1.1-1.1-1.2-1.2-1.2-1.61.51.31.61.71.40.3
Intermittent access day 1 total infusions0.10.21.0-0.1-0.1-0.40.30.10.70.0-0.0-0.00.10.30.20.20.00.90.50.80.80.51.0
Intermittent access day 15 total infusions0.30.51.90.00.0-0.40.30.11.00.0-0.1-0.0-0.0-0.10.00.1-0.11.41.11.21.20.91.3
Intermittent access terminal intake (last 3 days)0.40.53.0-0.1-0.1-0.50.20.20.80.0-0.2-0.2-0.10.00.00.1-0.11.31.11.21.21.01.7
Intermittent access total infusions0.20.31.50.10.1-0.60.40.00.80.20.00.00.30.30.40.40.10.90.60.80.80.51.2
Intermittent access day 1 locomotion0.30.40.90.70.7-0.80.8-0.50.80.70.60.70.60.90.50.70.9-0.3-0.5-0.4-0.3-0.50.2
Intermittent access day 15 total locomotion0.20.30.70.70.7-0.60.6-0.40.60.50.60.60.70.70.80.90.5-0.3-0.3-0.4-0.4-0.7-0.3
Intermittent access total locomotion0.20.20.50.40.4-0.50.4-0.40.40.40.50.50.50.60.50.60.5-0.5-0.4-0.7-0.5-0.5-0.0
Intermittent access standard deviation0.00.10.6-0.1-0.1-0.40.1-0.00.3-0.00.0-0.00.30.50.80.7-0.10.20.00.20.3-0.30.4
Left kidney weight2.611.919.74.44.4-3.94.1-4.23.54.44.04.13.74.13.33.23.9-1.9-2.1-1.3-1.6-1.71.2
Right kidney weight2.511.518.44.14.1-4.14.1-4.13.64.33.93.93.73.93.53.44.0-1.6-2.0-1.2-1.5-1.61.5
Cocaine induced anxiety0.40.61.1-1.0-1.00.9-1.00.9-1.0-1.0-0.8-0.8-0.9-0.7-0.8-0.8-0.80.10.10.10.20.3-0.4
Post-drug Anxiety0.50.51.3-1.1-1.10.6-1.00.8-0.8-1.0-0.6-0.8-0.6-0.8-0.5-0.5-1.00.40.40.50.40.5-0.1
Baseline Anxiety0.30.40.90.60.6-0.80.5-0.60.40.60.60.50.80.30.90.90.4-0.5-0.4-0.4-0.6-0.6-0.0
Tail length0.62.211.30.20.2-0.40.40.11.70.5-0.2-0.1-0.5-0.0-0.9-1.10.02.21.82.62.22.43.4
Length with tail0.41.58.40.70.7-1.31.1-0.81.91.10.70.70.71.00.30.20.61.30.81.91.51.42.9
Length without tail0.61.86.00.90.9-1.81.4-1.42.11.41.31.21.41.51.21.20.90.80.51.31.00.62.5
Times rat made contact with spout0.40.51.50.70.7-1.20.7-0.50.50.80.40.60.80.71.21.20.50.1-0.00.0-0.3-0.21.1
Lifetime Intake0.30.31.60.10.1-0.60.40.10.80.2-0.0-0.00.20.30.20.30.01.00.71.01.00.61.3
Liver weight, left0.81.32.41.21.2-1.51.3-1.51.51.41.31.21.41.31.41.41.2-0.1-0.30.1-0.2-0.31.0
Liver weight, right0.61.11.81.21.2-1.31.3-1.31.31.21.31.31.21.31.01.21.2-0.3-0.40.10.0-0.30.6
Locomotor activity0.50.82.61.11.1-1.01.3-1.11.61.10.91.00.50.40.20.21.10.60.30.70.50.80.9
Locomotor testing distance0.10.20.80.40.4-0.30.7-0.40.90.40.30.40.10.0-0.0-0.00.50.50.20.40.40.60.2
Locomotor testing rearing0.30.51.00.60.6-0.91.0-1.01.00.80.90.90.90.70.80.80.90.1-0.20.1-0.1-0.00.3
Locomotion in novel chamber2.22.94.7-1.6-1.62.2-1.61.8-0.7-2.0-1.8-1.8-1.9-2.1-1.8-1.8-2.21.81.71.11.41.2-0.9
Locomotion in novel chamber post-restriction0.81.42.2-1.1-1.11.1-1.11.0-0.4-1.1-1.1-1.1-1.2-1.2-1.4-1.4-1.21.21.21.31.51.50.6
Fecal boli incidents, locomotor time 10.30.51.90.70.7-0.91.0-0.91.40.60.80.90.80.30.80.70.50.30.1-0.0-0.1-0.2-0.1
Change in fecal boli incidents, locomotor task0.60.61.41.11.1-0.70.9-0.70.71.10.80.80.51.00.20.21.2-0.6-0.4-0.6-0.7-0.40.3
Time >=10cm from walls, locomotor time 10.60.61.30.70.7-0.70.3-0.9-0.30.60.60.60.91.01.01.10.7-1.1-1.0-0.7-0.8-1.1-0.6
Bouts of movement, locomotor time 10.40.51.7-0.9-0.9-0.0-0.20.20.1-0.60.1-0.1-0.20.1-0.2-0.3-0.40.90.81.31.30.81.2
Total resting periods, locomotor time 10.40.41.8-0.5-0.5-0.30.10.00.5-0.30.20.10.10.40.00.0-0.20.90.81.21.20.71.3
Rest time, locomotor task time 11.51.93.91.01.0-1.91.5-1.41.11.21.71.51.71.92.01.91.5-1.0-0.9-0.5-0.6-1.30.3
Distance moved, locomotor task time 10.40.61.5-0.3-0.31.2-0.60.8-0.3-0.6-0.9-0.8-1.0-1.1-1.2-1.1-0.80.70.70.30.50.7-0.5
Vertical activity count, locomotor time 10.51.22.5-1.1-1.11.5-1.41.3-1.1-1.3-1.3-1.2-1.3-1.6-1.2-1.2-1.30.50.70.00.10.5-0.9
Time >=10cm from walls, locomotor time 20.20.21.1-0.2-0.20.3-0.40.3-0.8-0.4-0.4-0.30.10.20.30.4-0.3-0.7-0.6-0.3-0.2-0.9-1.0
Bouts of movement, locomotor time 20.50.81.51.01.0-1.00.9-0.80.71.01.21.20.80.90.80.81.0-0.8-1.0-0.6-0.6-0.80.2
Total resting periods, locomotor time 20.50.91.51.01.0-1.21.0-0.80.61.11.21.20.91.00.90.81.1-0.8-1.0-0.5-0.6-0.70.5
Rest time, locomotor task time 20.10.20.60.10.1-0.50.1-0.2-0.40.20.30.30.30.30.40.40.4-0.7-0.8-0.4-0.4-0.4-0.2
Distance moved, locomotor task time 20.60.71.3-0.6-0.61.1-0.71.0-0.4-0.9-1.0-1.0-0.9-0.7-0.8-0.7-1.11.00.90.70.90.4-0.5
Vertical activity count, locomotor time 20.40.51.0-0.8-0.81.0-1.00.9-0.9-0.8-0.9-0.9-0.7-0.8-0.5-0.5-0.90.10.3-0.2-0.2-0.1-0.8
Light reinforcement 10.20.41.40.20.2-0.40.20.20.60.2-0.10.0-0.2-0.2-0.2-0.1-0.31.11.11.21.11.01.2
Light reinforcement 20.20.41.10.40.4-0.60.4-0.20.80.40.20.20.40.70.50.6-0.11.00.71.01.00.30.9
Bone: marrow area0.30.61.60.60.6-0.90.6-1.00.80.60.80.71.11.21.21.20.7-0.2-0.3-0.3-0.2-0.60.2
Bone: maximum diameter3.05.68.82.12.1-2.22.2-2.61.52.12.52.42.82.43.03.02.3-2.3-2.5-2.3-2.3-2.8-1.4
Bone: maximum force0.10.20.90.40.4-0.50.4-0.50.50.40.30.30.60.80.90.90.3-0.2-0.3-0.2-0.2-0.60.0
Bone: maximum moment0.30.51.20.70.7-0.80.7-0.70.90.70.60.60.81.01.11.10.5-0.0-0.2-0.0-0.1-0.50.3
Mean time between licks in bursts0.30.61.60.80.8-0.40.5-0.60.20.70.50.60.90.91.10.90.6-0.9-1.0-0.7-0.7-1.3-0.9
Mean num. licks in bursts1.21.82.91.31.3-1.51.1-1.30.31.41.31.31.41.11.51.61.4-1.5-1.4-1.6-1.7-1.4-0.5
Cd content in liver0.60.72.1-0.5-0.50.9-1.01.2-1.5-0.7-1.2-1.0-0.9-0.9-0.6-0.5-0.8-0.4-0.2-0.8-0.8-0.3-0.9
Co content in liver0.70.81.90.90.9-0.40.6-0.5-0.30.60.40.60.70.60.91.00.6-1.2-1.3-1.1-1.0-1.3-1.4
Cu content in liver1.01.22.5-1.1-1.10.9-0.91.1-0.2-1.2-1.3-1.2-0.9-0.9-0.6-0.8-1.41.51.51.51.61.00.5
Fe content in liver0.60.72.5-0.5-0.50.3-0.30.70.4-0.6-0.6-0.6-0.5-0.4-0.3-0.2-0.91.41.21.61.51.01.3
K content in liver0.60.61.91.41.4-0.51.0-0.90.70.90.81.00.80.90.60.60.5-0.4-0.3-0.4-0.1-0.6-0.5
Mg content in liver0.10.10.20.30.3-0.30.2-0.30.00.20.30.30.40.40.40.20.1-0.3-0.2-0.2-0.1-0.4-0.2
Mn content in liver2.52.74.71.51.5-1.81.6-1.81.11.51.81.72.02.02.22.21.6-1.4-1.4-1.4-1.4-1.9-0.5
Na content in liver0.10.11.0-0.1-0.10.5-0.10.2-0.4-0.4-0.1-0.1-0.1-0.2-0.1-0.2-0.4-0.2-0.0-0.20.0-0.3-1.0
Rb content in liver0.10.10.4-0.2-0.2-0.50.1-0.40.3-0.00.40.10.50.30.50.60.20.1-0.10.30.2-0.00.2
Se content in liver1.01.22.0-0.8-0.81.1-0.91.3-0.7-0.9-1.2-1.1-1.2-1.1-1.3-1.4-1.31.11.20.91.11.10.5
Sr content in liver0.30.20.6-0.7-0.70.5-0.40.5-0.3-0.8-0.5-0.5-0.3-0.4-0.1-0.1-0.60.50.40.40.50.1-0.3
Zn content in liver0.60.71.6-0.5-0.50.8-0.80.9-0.9-0.5-1.1-0.9-1.1-0.9-1.1-1.3-0.80.40.70.50.50.90.5
Bone: minimum diameter0.10.20.7-0.4-0.4-0.40.1-0.30.3-0.10.30.20.70.60.90.80.3-0.2-0.2-0.4-0.5-0.60.1
Time in familiar zone, hab. session 15.35.17.4-2.7-2.72.6-2.22.2-1.2-2.5-2.1-2.3-2.4-2.2-2.6-2.6-2.32.12.12.12.22.20.6
Time in novel zone, hab. session 14.44.46.82.62.6-2.52.2-2.01.42.62.12.22.22.12.22.22.3-1.7-1.8-1.9-2.1-1.70.2
Total zone transitions, hab. session 13.54.97.02.12.1-2.02.3-2.61.81.92.62.52.62.32.52.52.3-1.9-2.0-1.9-1.8-2.4-1.6
Total locomotion distance, hab. session 12.53.55.22.22.2-1.62.1-2.11.72.02.32.32.01.81.61.62.2-1.7-1.6-1.6-1.6-1.7-0.9
Locomotion velocity, hab. session 13.24.56.32.22.2-1.72.2-2.41.51.92.52.42.31.92.02.02.3-2.2-2.2-2.1-2.0-2.3-1.7
Time in familiar zone, hab. session 20.60.62.2-1.1-1.10.7-1.20.7-1.5-0.7-0.7-0.9-0.7-1.1-0.8-0.8-0.3-0.4-0.2-0.4-0.60.3-0.1
Time in novel zone, hab. session 21.92.03.51.81.8-1.41.9-1.51.91.41.51.61.51.71.61.71.2-0.4-0.7-0.5-0.4-1.1-0.1
Total zone transitions, hab. session 23.64.66.72.42.4-2.22.3-2.52.02.22.52.42.62.32.62.52.2-1.5-1.5-1.3-1.3-2.0-0.8
Total locomotion distance, hab. session 22.12.74.82.22.2-1.61.9-1.91.61.91.91.91.71.61.41.51.8-1.3-1.3-1.1-1.1-1.3-0.6
Locomotion velocity, hab. session 22.12.85.22.32.3-1.51.9-1.91.51.91.92.01.71.71.51.51.8-1.4-1.4-1.2-1.2-1.4-0.8
Novel to familiar place preference ratio0.40.41.6-0.1-0.1-0.20.1-0.4-0.40.10.40.40.30.20.30.20.7-1.1-1.0-1.3-1.2-0.8-0.7
Novelty place preference0.40.41.10.30.3-0.50.5-0.70.00.50.70.60.60.50.40.40.9-1.0-0.9-1.1-1.0-0.7-0.3
Time in novel zone, NPP test0.60.71.50.40.4-0.80.7-1.00.30.71.00.90.90.80.70.71.2-1.0-1.0-1.0-1.0-0.7-0.0
Total zone transitions, NPP test8.011.517.14.14.1-3.83.9-4.03.63.93.94.03.93.93.63.73.6-2.1-2.2-1.8-1.9-2.50.0
Total locomotion distance, NPP test5.17.011.33.43.4-2.93.2-3.23.13.13.23.22.92.92.62.52.9-1.4-1.5-1.0-1.2-1.70.3
Locomotion velocity, NPP test4.05.711.53.43.4-2.52.9-2.72.72.92.72.92.52.52.22.12.5-1.3-1.4-1.1-1.1-1.6-0.0
Intraocular pressure0.91.32.71.71.7-1.41.5-1.11.61.51.11.21.11.11.11.20.90.30.00.40.20.01.3
Delta distance traveled before/after self-admin0.60.61.4-0.8-0.80.9-0.80.9-0.8-0.8-0.9-0.9-1.1-0.9-1.2-1.2-0.60.40.40.40.30.80.5
Delta ambulatory time before/after self-admin0.60.71.7-0.7-0.70.9-0.70.8-0.4-0.7-0.7-0.8-1.0-0.8-1.3-1.3-0.60.80.80.70.71.10.7
Parametrial fat weight0.30.82.60.90.9-1.01.0-0.81.60.70.70.70.70.40.60.60.20.90.61.21.00.61.2
Pavlov. Cond. lever latency2.02.55.0-2.2-2.21.4-1.61.4-0.8-1.9-1.4-1.7-1.5-1.9-1.6-1.5-1.41.61.71.31.31.70.6
Pavlov. Cond. magazine entry latency2.83.65.62.22.2-2.01.8-1.81.22.21.92.02.12.42.22.21.9-1.7-1.9-1.4-1.5-2.0-0.4
Pavlov. Cond. change in total contacts0.80.91.41.21.2-0.90.7-0.70.21.10.70.80.91.11.11.10.8-1.1-1.1-0.9-0.9-1.1-0.4
Pavlov. Cond. index score2.63.35.42.32.3-1.71.7-1.60.82.11.71.91.82.12.01.91.7-1.9-2.0-1.6-1.6-2.1-0.9
Pavlov. Cond. latency score2.93.66.42.52.5-1.91.9-1.81.12.31.82.11.92.22.01.91.8-1.9-1.9-1.5-1.6-2.0-0.6
Pavlov. Cond. lever contacts2.73.35.52.42.4-1.51.6-1.60.62.11.61.81.72.11.91.81.7-2.1-2.1-1.7-1.7-2.1-1.0
Pavlov. Cond. magazine entry number1.31.62.5-1.5-1.51.1-1.11.1-0.5-1.4-1.1-1.2-1.3-1.6-1.5-1.5-1.11.41.41.11.01.60.7
Pavlov. Cond. intertrial magazine entries3.34.05.7-1.9-1.92.0-1.92.4-1.5-1.9-2.4-2.3-2.3-2.1-2.3-2.2-2.21.92.11.51.52.01.1
Pavlov. Cond. lever-magazine prob. diff.2.42.94.72.22.2-1.51.4-1.40.51.91.41.61.62.01.91.81.5-2.0-2.0-1.6-1.6-2.1-1.0
Pavlov. Cond. response bias1.11.42.61.51.5-1.01.0-1.00.51.31.01.11.21.61.51.50.9-1.2-1.2-0.9-0.9-1.5-0.6
Pavlov. Cond. lever latency0.30.41.1-1.0-1.01.0-0.90.7-0.7-0.9-0.7-0.8-0.7-0.3-0.6-0.5-0.60.30.30.30.40.1-0.3
Pavlov. Cond. magazine entry latency1.82.23.91.81.8-2.01.7-1.41.32.01.51.61.71.71.51.41.6-1.0-1.2-0.9-1.2-1.00.7
Pavlov. Cond. change in total contacts1.32.04.51.61.6-2.11.8-1.71.81.71.81.71.71.21.31.41.7-0.6-0.6-0.2-0.5-0.40.9
Pavlov. Cond. index score0.70.92.11.21.2-1.51.2-0.91.01.41.01.11.01.00.90.91.0-0.4-0.4-0.3-0.5-0.30.9
Pavlov. Cond. latency score0.81.02.21.21.2-1.51.2-1.01.11.41.01.11.11.00.90.91.1-0.5-0.5-0.3-0.5-0.30.9
Pavlov. Cond. lever contacts0.60.91.91.41.4-1.41.2-0.90.91.31.01.11.00.80.90.90.9-0.4-0.4-0.4-0.5-0.30.5
Pavlov. Cond. magazine entry number0.70.91.8-1.0-1.01.3-1.10.9-0.8-1.2-1.0-1.0-1.2-1.2-1.1-1.0-0.90.60.70.40.60.7-0.5
Pavlov. Cond. intertrial magazine entries4.16.211.0-3.0-3.03.3-3.12.8-2.7-3.1-2.7-2.8-2.9-2.9-2.8-2.7-2.81.21.40.71.01.3-1.3
Pavlov. Cond. lever-magazine prob. diff.0.81.02.31.21.2-1.51.2-1.01.01.41.01.21.11.01.00.91.1-0.5-0.5-0.3-0.5-0.30.9
Pavlov. Cond. response bias0.91.22.41.41.4-1.61.2-1.10.91.41.11.21.31.01.21.11.1-0.8-0.7-0.8-0.9-0.80.1
Time in closed arm before self-admin0.50.72.40.00.0-0.00.5-0.21.20.00.30.3-0.20.1-0.6-0.6-0.11.20.81.41.51.41.5
Time in closed arm after self-admin0.10.10.40.30.3-0.40.6-0.50.40.40.50.60.50.40.40.10.2-0.0-0.40.30.40.10.3
Time in open arm before self-admin0.10.10.30.00.00.0-0.20.0-0.1-0.2-0.1-0.10.1-0.40.40.3-0.30.10.3-0.2-0.3-0.3-0.6
Time in open arm after self-admin1.01.13.2-0.8-0.81.2-1.31.3-1.8-0.8-1.3-1.2-1.2-1.0-1.0-0.9-0.5-0.8-0.4-1.0-1.1-0.5-1.4
Bone: periosteal estimation0.92.04.51.01.0-1.41.2-1.61.21.11.51.41.91.72.12.11.2-1.0-1.2-1.1-1.1-1.7-0.7
Bone: periosteal perimeter1.93.36.51.11.1-1.51.2-1.80.51.21.61.52.11.72.42.51.7-2.1-2.3-2.2-2.2-2.5-1.5
Bone: post-yield work0.30.41.1-0.7-0.70.5-0.80.7-0.4-0.8-0.8-0.7-0.5-0.3-0.1-0.2-1.00.70.70.81.00.40.2
Progressive ratio test 1 active lever presses0.10.10.6-0.1-0.10.00.10.20.5-0.2-0.1-0.1-0.2-0.1-0.4-0.30.00.70.50.60.70.60.5
Progressive ratio test 1 breakpoint0.10.10.3-0.1-0.10.00.10.20.4-0.1-0.0-0.0-0.2-0.1-0.4-0.20.10.50.30.40.60.50.3
Progressive ratio test 1 inactive lever presses0.60.81.6-1.3-1.31.0-1.20.9-0.9-1.2-0.8-0.9-1.0-1.0-0.9-0.9-1.00.50.40.40.70.7-0.3
Progressive ratio test 2 active lever presses0.30.31.10.20.2-0.50.4-0.21.00.20.30.20.30.20.40.40.01.00.70.90.90.50.9
Progressive ratio test 2 breakpoint0.20.31.00.10.1-0.40.3-0.10.90.00.10.10.20.10.20.3-0.11.00.70.90.90.50.9
Progressive ratio test 2 inactive lever presses0.30.51.4-0.7-0.70.3-0.70.50.2-0.6-0.4-0.6-0.5-0.4-0.3-0.3-0.71.21.11.11.10.91.0
Incentive Sensitization - Responses0.40.61.60.40.4-1.00.5-0.51.10.40.60.40.90.71.21.30.00.90.50.80.7-0.11.0
Incentive Sensitization - Breakpoint0.40.51.60.40.4-1.00.5-0.61.10.40.60.50.90.71.21.20.00.80.50.80.7-0.10.9
Sum of active levers in priming session hrs 5-60.90.82.20.50.5-0.70.4-0.6-0.50.70.60.50.80.71.01.10.9-1.4-1.2-1.3-1.5-1.2-0.4
Progressive ratio1.92.94.62.22.2-1.72.0-1.71.61.91.81.82.11.91.81.91.6-1.3-1.2-1.3-1.3-1.7-0.2
Food seeking constrained by brief footshock0.40.51.70.40.4-0.40.3-0.3-0.30.30.30.40.60.80.80.90.4-0.9-1.2-0.8-0.7-1.3-0.9
Seeking ratio, punishment vs. effort0.60.82.1-1.4-1.40.8-1.31.0-1.4-1.3-1.0-1.0-0.9-0.7-0.5-0.5-0.90.50.20.60.70.4-0.3
Retroperitoneal fat weight1.04.49.52.52.5-2.62.8-2.73.12.32.72.62.42.02.22.12.1-0.4-0.7-0.2-0.4-0.70.6
Reaction time number correct0.10.10.7-0.8-0.80.1-0.40.0-0.3-0.4-0.0-0.2-0.2-0.3-0.3-0.30.20.20.20.1-0.00.40.3
Reaction time mean minus median0.10.41.20.70.7-0.50.2-0.3-0.30.70.30.40.40.50.30.40.6-1.1-1.0-0.9-1.0-0.6-0.2
Reaction time mean minus median AUC0.20.50.80.90.9-0.90.6-0.60.30.90.60.60.80.80.70.80.8-0.8-0.8-0.6-0.7-0.50.4
Reaction time num false alarms0.60.91.6-0.8-0.81.1-1.01.1-1.0-0.8-1.2-1.1-1.3-1.1-1.2-1.2-1.00.60.50.50.50.90.3
Reaction time num false alarms AUC0.91.42.6-1.1-1.11.4-1.31.5-1.5-1.1-1.6-1.4-1.6-1.4-1.6-1.5-1.20.50.50.40.50.90.1
Reaction time trials correct on left0.10.10.7-0.8-0.80.1-0.40.0-0.3-0.4-0.0-0.2-0.2-0.3-0.3-0.30.20.20.20.1-0.00.40.3
Reaction time trials on left0.10.10.7-0.8-0.80.1-0.40.0-0.3-0.4-0.0-0.2-0.2-0.3-0.3-0.30.20.10.20.0-0.10.40.3
Reaction time mean0.10.10.40.60.6-0.50.10.1-0.20.5-0.10.10.20.40.60.60.0-0.2-0.2-0.0-0.2-0.30.5
Reaction time mean AUC0.00.10.20.30.3-0.1-0.20.4-0.40.1-0.4-0.2-0.10.00.20.3-0.30.10.10.20.10.00.5
Median of all reaction times0.10.10.30.30.3-0.2-0.10.4-0.30.1-0.4-0.2-0.00.10.40.4-0.40.30.20.40.2-0.10.5
Reaction time omissions0.20.41.5-0.1-0.10.6-0.40.3-0.9-0.3-0.5-0.4-0.4-0.8-0.6-0.5-0.3-0.6-0.5-1.0-0.8-0.2-1.2
Reaction time false alarm rate0.50.71.4-0.4-0.41.0-0.81.2-0.8-0.6-1.2-1.0-1.2-0.9-1.1-1.1-1.10.60.60.60.70.80.3
Reaction time premature initiation rate0.30.41.3-0.3-0.30.6-0.50.7-0.2-0.4-0.7-0.6-0.6-0.2-0.4-0.5-0.80.70.71.11.10.60.5
Reaction time premature initiations0.10.20.4-0.5-0.50.5-0.50.5-0.4-0.5-0.5-0.5-0.4-0.2-0.3-0.4-0.40.30.30.60.60.40.2
Std. dev. reaction times0.10.20.50.60.6-0.20.1-0.0-0.30.4-0.00.10.20.20.30.30.3-0.7-0.7-0.6-0.7-0.4-0.1
Reaction time trials completed0.10.10.7-0.8-0.80.1-0.40.0-0.3-0.4-0.0-0.2-0.2-0.3-0.3-0.30.20.10.20.0-0.10.40.3
Reaction time trials AUC0.10.21.0-1.0-1.00.2-0.60.2-0.5-0.6-0.2-0.4-0.3-0.5-0.4-0.40.00.10.20.1-0.10.50.3
Run reversals in cocaine runway, females0.10.10.40.60.6-0.10.6-0.40.60.30.30.4-0.10.3-0.4-0.20.40.0-0.10.30.50.30.2
Run reversals in cocaine runway, males0.80.82.30.60.6-1.20.6-0.60.71.00.60.61.11.51.41.40.9-0.3-0.40.1-0.2-0.61.2
Latency to leave start box in cocaine runway1.82.14.1-1.9-1.91.7-2.01.6-1.8-1.8-1.6-1.6-1.4-1.5-1.3-1.4-1.70.50.90.40.60.6-0.8
Latency to leave start box in cocaine runway, F1.21.42.3-1.4-1.41.4-1.51.1-1.3-1.3-1.1-1.2-1.2-1.4-1.4-1.5-1.30.61.00.70.81.0-0.1
Latency to leave start box in cocaine runway, M1.11.01.9-1.4-1.41.1-1.41.3-1.1-1.4-1.3-1.2-0.9-0.7-0.5-0.5-1.30.60.50.30.50.0-0.8
Std. dev. time between licks in bursts0.60.85.6-0.4-0.40.7-0.50.1-1.0-0.6-0.2-0.20.1-0.20.10.1-0.1-1.3-1.1-1.3-1.1-1.4-2.4
Total sessions with >9 infusions0.20.30.6-0.4-0.40.4-0.20.6-0.1-0.4-0.5-0.4-0.5-0.5-0.7-0.5-0.40.80.70.60.70.70.2
Short access day 1 total inactive lever presses0.20.21.0-0.4-0.40.4-0.50.1-0.8-0.3-0.1-0.2-0.20.3-0.2-0.2-0.0-0.8-0.6-0.6-0.4-0.6-1.0
Short access day 10 total inactive lever presses0.40.92.20.20.2-0.40.1-0.9-0.10.30.80.60.90.91.31.10.4-1.3-1.3-1.5-1.4-1.5-1.0
Short access day 1 total infusions0.60.81.4-1.1-1.10.9-0.81.2-1.0-0.9-1.1-1.0-1.1-0.8-1.2-1.1-0.80.40.30.60.60.70.1
Short access day 10 total infusions0.20.20.60.40.4-0.80.8-0.40.60.60.40.50.60.50.50.50.60.1-0.10.20.30.10.6
Short access total infusions0.10.20.5-0.3-0.30.2-0.10.5-0.1-0.3-0.4-0.4-0.4-0.3-0.4-0.3-0.40.60.40.60.70.50.2
Short access day 1 locomotion0.10.20.6-0.3-0.30.7-0.20.4-0.4-0.4-0.3-0.3-0.5-0.7-0.7-0.7-0.3-0.1-0.1-0.00.10.3-0.6
Short access day 10 total locomotion0.81.54.10.50.5-0.50.4-0.9-0.30.50.90.81.00.81.11.20.8-1.9-1.9-2.0-1.9-1.9-1.7
Short access total locomotion0.50.61.20.70.7-0.50.8-0.70.40.60.80.80.70.50.50.60.8-1.0-1.0-1.1-1.0-0.9-0.9
One hour access (0.3 mA shock)0.91.02.2-1.0-1.00.4-0.70.9-0.1-0.8-0.7-0.8-0.9-0.9-0.9-0.8-0.81.51.51.31.31.51.4
Compulsive drug intake3.13.76.9-1.9-1.92.3-2.01.9-1.5-2.0-2.0-2.0-2.3-2.6-2.5-2.5-2.11.41.51.01.21.8-0.2
One hour access (shock baseline)0.30.52.7-0.4-0.4-0.5-0.10.20.4-0.1-0.1-0.20.10.40.40.5-0.21.10.91.21.10.61.6
Social response proportion0.20.20.80.10.10.5-0.50.6-0.9-0.1-0.7-0.5-0.5-0.2-0.5-0.4-0.3-0.3-0.2-0.3-0.2-0.1-0.4
Social responses0.00.00.1-0.2-0.2-0.0-0.20.3-0.3-0.3-0.3-0.3-0.1-0.10.10.2-0.10.20.20.40.40.00.1
Social time0.20.20.6-0.5-0.50.2-0.60.8-0.8-0.4-0.8-0.7-0.5-0.6-0.2-0.1-0.40.20.30.30.20.30.4
Soleus weight1.02.99.51.81.8-2.12.2-2.13.11.72.02.02.01.71.81.61.30.90.60.80.7-0.01.4
Bone: stiffness0.10.10.3-0.2-0.20.2-0.50.4-0.4-0.3-0.5-0.5-0.10.10.30.3-0.50.0-0.10.10.1-0.4-0.3
Tibialis anterior weight0.93.16.92.22.2-2.32.3-1.92.62.22.02.11.71.91.41.51.80.2-0.30.40.20.11.7
Time to tail flick, vehicle, before self-admin0.00.00.1-0.0-0.0-0.0-0.0-0.0-0.0-0.10.10.10.1-0.20.20.2-0.2-0.1-0.20.0-0.0-0.0-0.2
Time to tail flick, vehicle, after self-admin1.41.82.71.61.6-1.41.2-1.40.51.61.31.31.31.61.21.11.6-1.5-1.5-1.3-1.4-1.2-0.1
Time to tail flick, test, before self-admin0.30.30.7-0.6-0.60.5-0.50.6-0.3-0.8-0.6-0.5-0.4-0.3-0.10.0-0.60.70.30.60.80.1-0.4
Time to tail flick, test, after self-admin0.80.82.50.60.6-0.91.0-0.71.60.60.70.80.80.60.90.70.31.00.91.21.20.51.3
Delta time to tail flick, vehicle, before/after SA0.90.81.71.01.0-0.70.6-0.80.01.00.80.80.71.10.50.41.0-1.3-1.3-1.2-1.1-1.0-0.5
Delta time to tail flick, test, before/after SA0.50.62.00.70.7-0.80.8-0.81.30.80.70.70.60.30.40.20.40.60.80.70.50.61.4
Tibia length1.13.09.60.90.9-1.21.3-1.12.90.90.90.80.81.10.40.40.12.52.03.02.91.93.1
Ambulatory time before self-admin0.81.32.11.01.0-0.80.8-1.20.51.01.11.01.20.91.21.21.0-1.3-1.3-1.4-1.4-1.4-1.2
Ambulatory time after self-admin0.10.20.80.10.10.3-0.1-0.0-0.20.0-0.0-0.1-0.2-0.0-0.3-0.30.2-0.7-0.7-0.9-0.9-0.3-0.6
Bone: tissue strength1.11.14.00.30.3-0.70.5-0.31.50.20.20.20.20.00.10.1-0.21.71.61.91.81.42.0
Total heroin consumption0.50.63.40.50.5-1.20.7-0.40.50.80.30.40.71.11.01.20.6-0.1-0.40.30.20.01.9
Bone: trabecular number1.32.13.8-1.9-1.91.9-1.91.7-1.9-1.9-1.7-1.6-1.5-1.4-1.2-1.2-1.60.20.5-0.20.10.1-1.3
Bone: trabecular spacing0.10.10.3-0.0-0.0-0.30.5-0.60.6-0.10.40.30.3-0.30.10.10.30.30.20.30.30.3-0.2
Bone: trabecular thickness0.10.10.4-0.0-0.00.00.2-0.50.60.10.40.30.10.2-0.3-0.30.30.20.30.20.20.30.2
Bone: trabecular tissue density1.82.74.11.91.9-1.71.6-1.80.82.01.81.71.71.81.31.41.9-1.7-1.7-1.6-1.7-1.3-0.2
Water consumed over 24 hours0.30.31.7-0.5-0.5-0.1-0.20.50.1-0.2-0.5-0.4-0.3-0.2-0.00.1-0.41.10.90.90.70.71.3
Number of responses in last shaping day0.10.10.20.10.1-0.20.1-0.2-0.20.20.30.20.30.20.10.20.3-0.5-0.4-0.2-0.2-0.3-0.4